SGSM1_HUMAN
Evidence for PS localization
Functions
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SGSM1_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 100.0000 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RAB9A_HUMAN | [view interactions] | Low throughput | no | yes |
| RAB9B_HUMAN | [view interactions] | Low throughput | no | yes |
| NR4A2_HUMAN | [view interactions] | Low throughput | no | yes |
| CETN1_HUMAN | [view interactions] | High throughput | no | no |
| CETN2_HUMAN | [view interactions] | High throughput | no | yes |
| CETN3_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| RANB3_HUMAN | [view interactions] | High throughput | no | yes |
| ABCBA_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRL_HUMAN | [view interactions] | High throughput | no | no |
| ACADV_HUMAN | [view interactions] | High throughput | no | yes |
| PP4P2_HUMAN | [view interactions] | High throughput | no | yes |
| FANCI_HUMAN | [view interactions] | High throughput | no | yes |
| SGSM3_HUMAN | [view interactions] | Computational | no | yes |
| RAP2A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |