LRRK2_HUMAN

GO
G2C
SynGO
SynaptomeDB

HPA (protein expression in neurons)

Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S007
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 22228096
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S007
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 22228096
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S007
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 24282027
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 24282027
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 24282027
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 29541021
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: mouse-n2a
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: unspecified role
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 29541021
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 29541021
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-brain
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-brain
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 22639965
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-sh_sy5y
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 22228096
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-sh_sy5y
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 22228096
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-sh_sy5y
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 22228096
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-293t
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 23813973
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-brain
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 24282027
Interaction type: association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-brain
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 29541021
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: human-hela
Interaction detection method: confocal microscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 22639965
Interaction type: colocalization
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K1M6
Taxonomy: mouse
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
Host: mouse-cerebral_cortical_neuron
Interaction detection method: confocal microscopy
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
PMID: 22639965
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation
Host: mouse-cerebral_cortical_neuron
Interaction detection method: confocal microscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation
PMID: 22639965
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunocytochemistry
Host: rat-cortical_neuron
Interaction detection method: confocal microscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunocytochemistry
PMID: 24282027
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: O00429
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: -
Source: STRING [LRRK2_HUMAN] [DNM1L_HUMAN]
Original protein 2: Q5S007
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: -
Interaction type: -
Evidence: Computational