EGFR_HUMAN

GO
G2C
SynGO
SynaptomeDB

HPA (protein expression in neurons)

Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: two hybrid
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 25402006
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 24658140
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 9355745
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 9050838
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 7693694
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 7693694
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 8621392
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 9355745
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 10889023
Interaction type: association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: protein complementation assay
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 24658140
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: bioid
Source: Biogrid
Original protein 2: P18031
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 35384245
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: chlae-cos_1
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 9050838
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 24658140
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: Q01279
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: Identification by mass spectrometry
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 18515860
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: molecular weight estimation by coomasie staining
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: chlae-cos_1
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 9355745
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: polyclonal antibody immunostaining
Host: chlae-cos_1
Interaction detection method: fluorescence microscopy
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
PMID: 9050838
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
Host: human-mda_mb_436
Interaction detection method: fluorescence microscopy
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
PMID: 25796184
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: western blot
Host: -
Interaction detection method: protein kinase assay
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: western blot
PMID: 9355745
Interaction type: phosphorylation reaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: human-293t
Interaction detection method: ubiquitin reconstruction
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 24658140
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: yeasx
Interaction detection method: ubiquitin reconstruction
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 31980649
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: competition binding
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: peptide synthesis
Host: -
Interaction detection method: competition binding
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: direct interaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: competition binding
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: competition binding
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: competition binding
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 7693694
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: peptide synthesis
Host: -
Interaction detection method: protein cross-linking with a bifunctional reagent
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 8621392
Interaction type: direct interaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: peptide synthesis
Host: -
Interaction detection method: phosphatase assay
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 8621392
Interaction type: dephosphorylation reaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: peptide synthesis
Host: -
Interaction detection method: phosphatase assay
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 8621392
Interaction type: dephosphorylation reaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: peptide synthesis
Host: -
Interaction detection method: phosphatase assay
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 7685104
Interaction type: phosphorylation reaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P00533
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: peptide synthesis
Host: -
Interaction detection method: phosphatase assay
Source: Intact
Original protein 2: P20417
Taxonomy: rat
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 7685104
Interaction type: phosphorylation reaction
Evidence: LT
Inferred: -
Original protein 1: P00533
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-293lp-In T-REx
Interaction detection method: proximity-dependent biotin identification
Source: Intact
Original protein 2: P18031
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 35384245
Interaction type: proximity
Evidence: HT