Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

5NT1B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Dephosphorylates the 5 and 2(3)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in 5NT1B_HUMAN
GO:0046872 metal ion binding 37.5000 4 yes
GO:0005524 ATP binding 37.5000 5 no
GO:0017076 purine nucleotide binding 37.5000 4 no
GO:0030554 adenyl nucleotide binding 37.5000 5 no
GO:0032555 purine ribonucleotide binding 37.5000 4 no
GO:0032559 adenyl ribonucleotide binding 37.5000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 37.5000 4 no
GO:0008252 nucleotidase activity 25.0000 6 yes
GO:0008253 5-nucleotidase activity 25.0000 7 yes
GO:0016791 phosphatase activity 25.0000 5 yes
GO:0042578 phosphoric ester hydrolase activity 25.0000 4 yes
GO:0016301 kinase activity 25.0000 4 no
GO:0016776 phosphotransferase activity, phosphate group as acceptor 25.0000 4 no
GO:0019205 nucleobase-containing compound kinase activity 25.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in 5NT1B_HUMAN
GO:0006163 purine nucleotide metabolic process 62.5000 5 yes
GO:0006753 nucleoside phosphate metabolic process 62.5000 4 yes
GO:0006796 phosphate-containing compound metabolic process 62.5000 4 yes
GO:0009117 nucleotide metabolic process 62.5000 5 yes
GO:0072521 purine-containing compound metabolic process 62.5000 4 yes
GO:0018130 heterocycle biosynthetic process 50.0000 4 no
GO:0019438 aromatic compound biosynthetic process 50.0000 4 no
GO:0034654 nucleobase-containing compound biosynthetic process 50.0000 4 no
GO:0044271 cellular nitrogen compound biosynthetic process 50.0000 4 no
GO:0072522 purine-containing compound biosynthetic process 50.0000 5 no
GO:1901137 carbohydrate derivative biosynthetic process 50.0000 4 no
GO:1901362 organic cyclic compound biosynthetic process 50.0000 4 no
GO:1901566 organonitrogen compound biosynthetic process 50.0000 4 no
GO:0009116 nucleoside metabolic process 37.5000 4 yes
GO:1901657 glycosyl compound metabolic process 37.5000 4 yes
GO:0006164 purine nucleotide biosynthetic process 37.5000 6 no
GO:0009123 nucleoside monophosphate metabolic process 37.5000 5 no
GO:0009126 purine nucleoside monophosphate metabolic process 37.5000 6 no
GO:0009150 purine ribonucleotide metabolic process 37.5000 6 no
GO:0009161 ribonucleoside monophosphate metabolic process 37.5000 6 no
GO:0009165 nucleotide biosynthetic process 37.5000 6 no
GO:0009167 purine ribonucleoside monophosphate metabolic process 37.5000 7 no
GO:0009259 ribonucleotide metabolic process 37.5000 5 no
GO:0019693 ribose phosphate metabolic process 37.5000 4 no
GO:0046033 AMP metabolic process 37.5000 7 no
GO:0090407 organophosphate biosynthetic process 37.5000 4 no
GO:1901293 nucleoside phosphate biosynthetic process 37.5000 5 no
GO:0009132 nucleoside diphosphate metabolic process 37.5000 5 no
GO:0009135 purine nucleoside diphosphate metabolic process 37.5000 6 no
GO:0009179 purine ribonucleoside diphosphate metabolic process 25.0000 7 no
GO:0009185 ribonucleoside diphosphate metabolic process 25.0000 6 no
GO:0046031 ADP metabolic process 25.0000 7 no
GO:0009133 nucleoside diphosphate biosynthetic process 25.0000 6 no
GO:0009136 purine nucleoside diphosphate biosynthetic process 25.0000 7 no
GO:0006195 purine nucleotide catabolic process 25.0000 6 yes
GO:0009119 ribonucleoside metabolic process 25.0000 5 yes
GO:0009166 nucleotide catabolic process 25.0000 6 yes
GO:0019439 aromatic compound catabolic process 25.0000 4 yes
GO:0034655 nucleobase-containing compound catabolic process 25.0000 4 yes
GO:0042278 purine nucleoside metabolic process 25.0000 5 yes
GO:0044270 cellular nitrogen compound catabolic process 25.0000 4 yes
GO:0046085 adenosine metabolic process 25.0000 7 yes
GO:0046128 purine ribonucleoside metabolic process 25.0000 6 yes
GO:0046434 organophosphate catabolic process 25.0000 4 yes
GO:0046700 heterocycle catabolic process 25.0000 4 yes
GO:0072523 purine-containing compound catabolic process 25.0000 5 yes
GO:1901292 nucleoside phosphate catabolic process 25.0000 5 yes
GO:1901361 organic cyclic compound catabolic process 25.0000 4 yes
GO:1901565 organonitrogen compound catabolic process 25.0000 4 yes
GO:0009152 purine ribonucleotide biosynthetic process 25.0000 7 no
GO:0009260 ribonucleotide biosynthetic process 25.0000 6 no
GO:0046390 ribose phosphate biosynthetic process 25.0000 5 no
GO:0032446 protein modification by small protein conjugation 25.0000 6 no
GO:0036211 protein modification process 25.0000 4 no
GO:0043412 macromolecule modification 25.0000 4 no
GO:0048522 positive regulation of cellular process 25.0000 4 no
GO:0070647 protein modification by small protein conjugation or removal 25.0000 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
AGRIN_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
NADC_HUMAN [view interactions] Computational no yes
ENTP4_HUMAN [view interactions] Computational no yes
KITH_HUMAN [view interactions] Computational no yes
NT5M_HUMAN [view interactions] Computational no yes
GMPR1_HUMAN [view interactions] Computational no yes
UPP_HUMAN [view interactions] Computational no no
5NT1A_HUMAN [view interactions] Computational no yes
DUT_HUMAN [view interactions] Computational no yes
NUD16_HUMAN [view interactions] Computational no yes
NAMPT_HUMAN [view interactions] Computational no no
CMPK2_HUMAN [view interactions] Computational no yes
HPRT_HUMAN [view interactions] Computational no yes
APT_HUMAN [view interactions] Computational no yes
5NTC_HUMAN [view interactions] Computational no yes
KGUA_HUMAN [view entry] [view interactions] Computational yes yes
DGUOK_HUMAN [view interactions] Computational no yes
TYPH_HUMAN [view interactions] Computational no no
5NT3B_HUMAN [view interactions] Computational no yes
ITPA_HUMAN [view interactions] Computational no yes
5NTD_HUMAN [view entry] [view interactions] Computational yes yes
DCK_HUMAN [view interactions] Computational no no
NUD12_HUMAN [view interactions] Computational no yes
PUR9_HUMAN [view entry] [view interactions] Computational yes yes
TYSY_HUMAN [view interactions] Computational no yes
KAD3_HUMAN [view entry] [view interactions] Computational yes yes
ADA_HUMAN [view interactions] Computational no no
GUAA_HUMAN [view interactions] Computational no no
NT5C_HUMAN [view interactions] Computational no yes
DCTD_HUMAN [view interactions] Computational no yes
PNPH_HUMAN [view interactions] Computational no no
CDD_HUMAN [view interactions] Computational no no
PNCB_HUMAN [view interactions] Computational no no
KTHY_HUMAN [view interactions] Computational no yes
DCTP1_HUMAN [view interactions] Computational no no
UMPS_HUMAN [view interactions] Computational no no
PUR8_HUMAN [view interactions] Computational no yes
ENTP8_HUMAN [view interactions] Computational no no