Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

BCAS1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Required for myelination. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in BCAS1_HUMAN
GO:0046872 metal ion binding 50.0000 4 no
GO:0005509 calcium ion binding 41.6667 5 no
GO:0019900 kinase binding 41.6667 4 no
GO:0019887 protein kinase regulator activity 33.3333 4 no
GO:0019888 protein phosphatase regulator activity 33.3333 4 no
GO:0019901 protein kinase binding 33.3333 5 no
GO:0003779 actin binding 33.3333 4 no
GO:0001664 G protein-coupled receptor binding 25.0000 4 no
GO:0008179 adenylate cyclase binding 25.0000 4 no
GO:0010856 adenylate cyclase activator activity 25.0000 4 no
GO:0019209 kinase activator activity 25.0000 4 no
GO:0019211 phosphatase activator activity 25.0000 4 no
GO:0030295 protein kinase activator activity 25.0000 5 no
GO:0031432 titin binding 25.0000 4 no
GO:0031997 N-terminal myristoylation domain binding 25.0000 4 no
GO:0035254 glutamate receptor binding 25.0000 4 no
GO:0043539 protein serine/threonine kinase activator activity 25.0000 6 no
GO:0072542 protein phosphatase activator activity 25.0000 5 no
GO:0097718 disordered domain specific binding 25.0000 4 no
GO:0015631 tubulin binding 25.0000 4 no
GO:0046914 transition metal ion binding 25.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in BCAS1_HUMAN
GO:0048523 negative regulation of cellular process 75.0000 4 no
GO:0009892 negative regulation of metabolic process 66.6667 4 no
GO:0009966 regulation of signal transduction 66.6667 4 no
GO:0010563 negative regulation of phosphorus metabolic process 66.6667 6 no
GO:0010646 regulation of cell communication 66.6667 4 no
GO:0019220 regulation of phosphate metabolic process 66.6667 6 no
GO:0031323 regulation of cellular metabolic process 66.6667 4 no
GO:0031324 negative regulation of cellular metabolic process 66.6667 5 no
GO:0042325 regulation of phosphorylation 66.6667 7 no
GO:0045936 negative regulation of phosphate metabolic process 66.6667 7 no
GO:0048522 positive regulation of cellular process 66.6667 4 no
GO:0051174 regulation of phosphorus metabolic process 66.6667 5 no
GO:0080090 regulation of primary metabolic process 58.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 58.3333 5 no
GO:0031399 regulation of protein modification process 58.3333 6 no
GO:0031400 negative regulation of protein modification process 58.3333 7 no
GO:0042326 negative regulation of phosphorylation 58.3333 8 no
GO:0051171 regulation of nitrogen compound metabolic process 58.3333 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 58.3333 5 no
GO:0051246 regulation of protein metabolic process 58.3333 5 no
GO:0051248 negative regulation of protein metabolic process 58.3333 6 no
GO:0060255 regulation of macromolecule metabolic process 58.3333 4 no
GO:0099177 regulation of trans-synaptic signaling 50.0000 4 no
GO:1904062 regulation of cation transmembrane transport 50.0000 6 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0001932 regulation of protein phosphorylation 50.0000 7 no
GO:0006996 organelle organization 50.0000 4 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0010038 response to metal ion 50.0000 4 no
GO:0010562 positive regulation of phosphorus metabolic process 50.0000 6 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0022898 regulation of transmembrane transporter activity 50.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0033674 positive regulation of kinase activity 50.0000 6 no
GO:0034762 regulation of transmembrane transport 50.0000 4 no
GO:0034765 regulation of ion transmembrane transport 50.0000 5 no
GO:0042327 positive regulation of phosphorylation 50.0000 8 no
GO:0043085 positive regulation of catalytic activity 50.0000 4 no
GO:0043269 regulation of ion transport 50.0000 5 no
GO:0043549 regulation of kinase activity 50.0000 5 no
GO:0045937 positive regulation of phosphate metabolic process 50.0000 7 no
GO:0050804 modulation of chemical synaptic transmission 50.0000 5 no
GO:0051049 regulation of transport 50.0000 4 no
GO:0051050 positive regulation of transport 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 50.0000 5 no
GO:0051247 positive regulation of protein metabolic process 50.0000 6 no
GO:0051336 regulation of hydrolase activity 50.0000 4 no
GO:0051338 regulation of transferase activity 50.0000 4 no
GO:0051347 positive regulation of transferase activity 50.0000 5 no
GO:1902531 regulation of intracellular signal transduction 41.6667 5 no
GO:1903169 regulation of calcium ion transmembrane transport 41.6667 7 no
GO:1904064 positive regulation of cation transmembrane transport 41.6667 7 no
GO:0030030 cell projection organization 41.6667 4 no
GO:0120036 plasma membrane bounded cell projection organization 41.6667 5 no
GO:0001933 negative regulation of protein phosphorylation 41.6667 8 no
GO:0001934 positive regulation of protein phosphorylation 41.6667 8 no
GO:0010959 regulation of metal ion transport 41.6667 6 no
GO:0019722 calcium-mediated signaling 41.6667 5 no
GO:0019932 second-messenger-mediated signaling 41.6667 4 no
GO:0031401 positive regulation of protein modification process 41.6667 7 no
GO:0032412 regulation of ion transmembrane transporter activity 41.6667 5 no
GO:0034764 positive regulation of transmembrane transport 41.6667 5 no
GO:0034767 positive regulation of ion transmembrane transport 41.6667 6 no
GO:0043270 positive regulation of ion transport 41.6667 5 no
GO:0045859 regulation of protein kinase activity 41.6667 6 no
GO:0045860 positive regulation of protein kinase activity 41.6667 7 no
GO:0050848 regulation of calcium-mediated signaling 41.6667 6 no
GO:0051345 positive regulation of hydrolase activity 41.6667 5 no
GO:0051924 regulation of calcium ion transport 41.6667 7 no
GO:0071900 regulation of protein serine/threonine kinase activity 33.3333 7 no
GO:0071902 positive regulation of protein serine/threonine kinase activity 33.3333 8 no
GO:1904427 positive regulation of calcium ion transmembrane transport 33.3333 7 no
GO:2001257 regulation of cation channel activity 33.3333 6 no
GO:2001259 positive regulation of cation channel activity 33.3333 6 no
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0050890 cognition 33.3333 4 no
GO:0051129 negative regulation of cellular component organization 33.3333 5 no
GO:0071310 cellular response to organic substance 33.3333 4 no
GO:1901701 cellular response to oxygen-containing compound 33.3333 4 no
GO:0007005 mitochondrion organization 33.3333 5 no
GO:0010243 response to organonitrogen compound 33.3333 4 no
GO:0010564 regulation of cell cycle process 33.3333 5 no
GO:0010921 regulation of phosphatase activity 33.3333 5 no
GO:0010941 regulation of cell death 33.3333 4 no
GO:0010942 positive regulation of cell death 33.3333 5 no
GO:0021762 substantia nigra development 33.3333 4 no
GO:0032410 negative regulation of transporter activity 33.3333 4 no
GO:0032411 positive regulation of transporter activity 33.3333 4 no
GO:0032414 positive regulation of ion transmembrane transporter activity 33.3333 5 no
GO:0035303 regulation of dephosphorylation 33.3333 7 no
GO:0035304 regulation of protein dephosphorylation 33.3333 7 no
GO:0043271 negative regulation of ion transport 33.3333 5 no
GO:0043666 regulation of phosphoprotein phosphatase activity 33.3333 6 no
GO:0044057 regulation of system process 33.3333 4 no
GO:0051051 negative regulation of transport 33.3333 4 no
GO:0051279 regulation of release of sequestered calcium ion into cytosol 33.3333 5 no
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 33.3333 6 no
GO:0051282 regulation of sequestering of calcium ion 33.3333 4 no
GO:0051726 regulation of cell cycle 33.3333 4 no
GO:0051928 positive regulation of calcium ion transport 33.3333 6 no
GO:0061024 membrane organization 25.0000 4 no
GO:0090257 regulation of muscle system process 25.0000 5 no
GO:1901019 regulation of calcium ion transmembrane transporter activity 25.0000 6 no
GO:1901020 negative regulation of calcium ion transmembrane transporter activity 25.0000 6 no
GO:1901021 positive regulation of calcium ion transmembrane transporter activity 25.0000 6 no
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 25.0000 6 no
GO:1903170 negative regulation of calcium ion transmembrane transport 25.0000 7 no
GO:1903522 regulation of blood circulation 25.0000 5 no
GO:1904063 negative regulation of cation transmembrane transport 25.0000 7 no
GO:1905912 regulation of calcium ion export across plasma membrane 25.0000 8 no
GO:1905913 negative regulation of calcium ion export across plasma membrane 25.0000 8 no
GO:2001258 negative regulation of cation channel activity 25.0000 6 no
GO:0007613 memory 25.0000 4 no
GO:0010468 regulation of gene expression 25.0000 5 no
GO:0010639 negative regulation of organelle organization 25.0000 6 no
GO:0030162 regulation of proteolysis 25.0000 6 no
GO:0031175 neuron projection development 25.0000 6 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0034330 cell junction organization 25.0000 4 no
GO:0043086 negative regulation of catalytic activity 25.0000 4 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0050808 synapse organization 25.0000 5 no
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:0051259 protein complex oligomerization 25.0000 6 no
GO:0051493 regulation of cytoskeleton organization 25.0000 6 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:0070925 organelle assembly 25.0000 5 no
GO:0097435 supramolecular fiber organization 25.0000 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:1901214 regulation of neuron death 25.0000 5 no
GO:1901216 positive regulation of neuron death 25.0000 6 no
GO:1902903 regulation of supramolecular fiber organization 25.0000 5 no
GO:1903829 positive regulation of protein localization 25.0000 5 no
GO:0050807 regulation of synapse organization 25.0000 5 no
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no
GO:0000086 G2/M transition of mitotic cell cycle 25.0000 5 no
GO:0005513 detection of calcium ion 25.0000 4 no
GO:0006937 regulation of muscle contraction 25.0000 6 no
GO:0006942 regulation of striated muscle contraction 25.0000 7 no
GO:0007006 mitochondrial membrane organization 25.0000 5 no
GO:0008016 regulation of heart contraction 25.0000 6 no
GO:0008104 protein localization 25.0000 4 no
GO:0010649 regulation of cell communication by electrical coupling 25.0000 5 no
GO:0010799 regulation of peptidyl-threonine phosphorylation 25.0000 8 no
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 25.0000 9 no
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 25.0000 9 no
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 25.0000 6 no
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 25.0000 7 no
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 25.0000 6 no
GO:0010922 positive regulation of phosphatase activity 25.0000 6 no
GO:0014070 response to organic cyclic compound 25.0000 4 no
GO:0031952 regulation of protein autophosphorylation 25.0000 8 no
GO:0031954 positive regulation of protein autophosphorylation 25.0000 9 no
GO:0032413 negative regulation of ion transmembrane transporter activity 25.0000 5 no
GO:0032465 regulation of cytokinesis 25.0000 5 no
GO:0032516 positive regulation of phosphoprotein phosphatase activity 25.0000 7 no
GO:0033993 response to lipid 25.0000 4 no
GO:0034763 negative regulation of transmembrane transport 25.0000 5 no
GO:0034766 negative regulation of ion transmembrane transport 25.0000 6 no
GO:0035306 positive regulation of dephosphorylation 25.0000 8 no
GO:0035307 positive regulation of protein dephosphorylation 25.0000 8 no
GO:0042981 regulation of apoptotic process 25.0000 6 no
GO:0043065 positive regulation of apoptotic process 25.0000 7 no
GO:0043067 regulation of programmed cell death 25.0000 5 no
GO:0043068 positive regulation of programmed cell death 25.0000 6 no
GO:0043388 positive regulation of DNA binding 25.0000 5 no
GO:0044772 mitotic cell cycle phase transition 25.0000 4 no
GO:0044839 cell cycle G2/M phase transition 25.0000 4 no
GO:0051099 positive regulation of binding 25.0000 4 no
GO:0051101 regulation of DNA binding 25.0000 4 no
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 25.0000 6 no
GO:0051284 positive regulation of sequestering of calcium ion 25.0000 5 no
GO:0051302 regulation of cell division 25.0000 4 no
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 25.0000 5 no
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 25.0000 6 no
GO:0051592 response to calcium ion 25.0000 5 no
GO:0051926 negative regulation of calcium ion transport 25.0000 6 no
GO:0055117 regulation of cardiac muscle contraction 25.0000 7 no
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 25.0000 6 no
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 25.0000 7 no
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 25.0000 7 no
GO:0042552 myelination 16.6667 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in BCAS1_HUMAN
DOID:0050700 cardiomyopathy 16.6667 4 no
DOID:0060036 intrinsic cardiomyopathy 16.6667 5 no
DOID:114 heart disease 16.6667 3 no
DOID:2843 long QT syndrome 16.6667 6 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DYL1_HUMAN [view entry] [view interactions] Low throughput yes no
BCAS1_HUMAN [view entry] [view interactions] Low throughput yes no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
GGN_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
RUVB2_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes