CADM2_HUMAN
Evidence for PS localization
Functions
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CADM2_HUMAN |
|---|---|---|---|---|
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules | 50.0000 | 5 | yes |
| GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 50.0000 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CADM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |