Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CPT1C_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May play a role in lipid metabolic process. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
37 Arg Cys Spasticparaplegia73,autosomaldominant(SPG73) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in CPT1C_HUMAN
GO:0004970 glutamate-gated receptor activity 66.6667 4 no
GO:0004971 AMPA glutamate receptor activity 66.6667 5 no
GO:0005216 monoatomic ion channel activity 66.6667 4 no
GO:0005230 extracellular ligand-gated monoatomic ion channel activity 66.6667 6 no
GO:0008066 glutamate receptor activity 66.6667 4 no
GO:0015267 channel activity 66.6667 4 no
GO:0015276 ligand-gated monoatomic ion channel activity 66.6667 5 no
GO:0022824 transmitter-gated monoatomic ion channel activity 66.6667 5 no
GO:0022834 ligand-gated channel activity 66.6667 6 no
GO:0022835 transmitter-gated channel activity 66.6667 4 no
GO:0022836 gated channel activity 66.6667 5 no
GO:0022890 inorganic cation transmembrane transporter activity 66.6667 4 no
GO:0046943 carboxylic acid transmembrane transporter activity 66.6667 4 no
GO:0098960 postsynaptic neurotransmitter receptor activity 66.6667 4 no
GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 66.6667 5 no
GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 66.6667 6 no

Biological process

Term Name % Distance from top the of the tree Annotated in CPT1C_HUMAN
GO:0007268 chemical synaptic transmission 66.6667 7 no
GO:0010646 regulation of cell communication 66.6667 4 no
GO:0035249 synaptic transmission, glutamatergic 66.6667 8 no
GO:0050804 modulation of chemical synaptic transmission 66.6667 5 no
GO:0098916 anterograde trans-synaptic signaling 66.6667 6 no
GO:0099177 regulation of trans-synaptic signaling 66.6667 4 no
GO:0099536 synaptic signaling 66.6667 4 no
GO:0099537 trans-synaptic signaling 66.6667 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
PPM1F_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
GRIA1_HUMAN [view entry] [view interactions] High throughput yes yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes