Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IGS11_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in IGS11_HUMAN
GO:0035254 glutamate receptor binding 100.0000 4 yes
GO:0035255 ionotropic glutamate receptor binding 100.0000 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IGS11_HUMAN
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 100.0000 5 yes
GO:0009966 regulation of signal transduction 100.0000 4 yes
GO:0009967 positive regulation of signal transduction 100.0000 5 yes
GO:0010646 regulation of cell communication 100.0000 4 yes
GO:0010647 positive regulation of cell communication 100.0000 5 yes
GO:0023056 positive regulation of signaling 100.0000 4 yes
GO:0031644 regulation of nervous system process 100.0000 5 yes
GO:0044057 regulation of system process 100.0000 4 yes
GO:0048522 positive regulation of cellular process 100.0000 4 yes
GO:0048584 positive regulation of response to stimulus 100.0000 4 yes
GO:0050804 modulation of chemical synaptic transmission 100.0000 5 yes
GO:0050806 positive regulation of synaptic transmission 100.0000 5 yes
GO:0061884 regulation of mini excitatory postsynaptic potential 100.0000 5 yes
GO:0061885 positive regulation of mini excitatory postsynaptic potential 100.0000 6 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 100.0000 4 yes
GO:0098815 modulation of excitatory postsynaptic potential 100.0000 4 yes
GO:0099177 regulation of trans-synaptic signaling 100.0000 4 yes
GO:1900271 regulation of long-term synaptic potentiation 100.0000 4 yes
GO:1900273 positive regulation of long-term synaptic potentiation 100.0000 5 yes
GO:2000463 positive regulation of excitatory postsynaptic potential 100.0000 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
IGS11_HUMAN [view entry] [view interactions] High throughput yes yes
LXN_HUMAN [view interactions] High throughput no yes