ITAX_HUMAN
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
No data found.
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in ITAX_HUMAN |
---|---|---|---|---|
GO:0009889 | regulation of biosynthetic process | 100.0000 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 100.0000 | 5 | yes |
GO:0009893 | positive regulation of metabolic process | 100.0000 | 4 | yes |
GO:0010468 | regulation of gene expression | 100.0000 | 6 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 100.0000 | 5 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 100.0000 | 6 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 100.0000 | 5 | yes |
GO:0010628 | positive regulation of gene expression | 100.0000 | 7 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 100.0000 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 100.0000 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 100.0000 | 5 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 100.0000 | 5 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 100.0000 | 6 | yes |
GO:0045765 | regulation of angiogenesis | 100.0000 | 5 | yes |
GO:0045766 | positive regulation of angiogenesis | 100.0000 | 6 | yes |
GO:0048522 | positive regulation of cellular process | 100.0000 | 4 | yes |
GO:0051094 | positive regulation of developmental process | 100.0000 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 100.0000 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 100.0000 | 4 | yes |
GO:0140546 | defense response to symbiont | 100.0000 | 4 | yes |
GO:1901342 | regulation of vasculature development | 100.0000 | 5 | yes |
GO:1904018 | positive regulation of vasculature development | 100.0000 | 5 | yes |
GO:2000026 | regulation of multicellular organismal development | 100.0000 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
TGO1_HUMAN | [view interactions] | Low throughput | no | yes |
CO3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NHLC2_HUMAN | [view interactions] | High throughput | no | yes |