OX2G_HUMAN
Evidence for PS localization
Functions
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in OX2G_HUMAN |
|---|---|---|---|---|
| GO:0086080 | protein binding involved in heterotypic cell-cell adhesion | 66.6667 | 6 | yes |
| GO:0098631 | cell adhesion mediator activity | 66.6667 | 4 | yes |
| GO:0098632 | cell-cell adhesion mediator activity | 66.6667 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in OX2G_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 66.6667 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 66.6667 | 4 | yes |
| GO:0050708 | regulation of protein secretion | 66.6667 | 5 | yes |
| GO:0050709 | negative regulation of protein secretion | 66.6667 | 6 | yes |
| GO:0050727 | regulation of inflammatory response | 66.6667 | 5 | yes |
| GO:0050728 | negative regulation of inflammatory response | 66.6667 | 6 | yes |
| GO:0050776 | regulation of immune response | 66.6667 | 4 | yes |
| GO:0050865 | regulation of cell activation | 66.6667 | 4 | yes |
| GO:0050866 | negative regulation of cell activation | 66.6667 | 5 | yes |
| GO:0051046 | regulation of secretion | 66.6667 | 5 | yes |
| GO:0051048 | negative regulation of secretion | 66.6667 | 5 | yes |
| GO:0051049 | regulation of transport | 66.6667 | 4 | yes |
| GO:0051051 | negative regulation of transport | 66.6667 | 4 | yes |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 66.6667 | 4 | yes |
| GO:0051223 | regulation of protein transport | 66.6667 | 5 | yes |
| GO:0051224 | negative regulation of protein transport | 66.6667 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 66.6667 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 66.6667 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 66.6667 | 5 | yes |
| GO:0051336 | regulation of hydrolase activity | 66.6667 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 66.6667 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 66.6667 | 5 | yes |
| GO:0051347 | positive regulation of transferase activity | 66.6667 | 5 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 66.6667 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 66.6667 | 4 | yes |
| GO:0070201 | regulation of establishment of protein localization | 66.6667 | 6 | yes |
| GO:0071634 | regulation of transforming growth factor beta production | 66.6667 | 5 | yes |
| GO:0071636 | positive regulation of transforming growth factor beta production | 66.6667 | 6 | yes |
| GO:0071675 | regulation of mononuclear cell migration | 66.6667 | 5 | yes |
| GO:0071676 | negative regulation of mononuclear cell migration | 66.6667 | 6 | yes |
| GO:0080090 | regulation of primary metabolic process | 66.6667 | 4 | yes |
| GO:0080134 | regulation of response to stress | 66.6667 | 4 | yes |
| GO:0150070 | regulation of arginase activity | 66.6667 | 5 | yes |
| GO:0150072 | positive regulation of arginase activity | 66.6667 | 6 | yes |
| GO:0150073 | regulation of protein-glutamine gamma-glutamyltransferase activity | 66.6667 | 5 | yes |
| GO:0150074 | positive regulation of protein-glutamine gamma-glutamyltransferase activity | 66.6667 | 6 | yes |
| GO:0150077 | regulation of neuroinflammatory response | 66.6667 | 6 | yes |
| GO:0150079 | negative regulation of neuroinflammatory response | 66.6667 | 7 | yes |
| GO:1903530 | regulation of secretion by cell | 66.6667 | 4 | yes |
| GO:1903531 | negative regulation of secretion by cell | 66.6667 | 5 | yes |
| GO:1903828 | negative regulation of protein localization | 66.6667 | 5 | yes |
| GO:1904464 | regulation of matrix metallopeptidase secretion | 66.6667 | 6 | yes |
| GO:1904465 | negative regulation of matrix metallopeptidase secretion | 66.6667 | 7 | yes |
| GO:1904950 | negative regulation of establishment of protein localization | 66.6667 | 6 | yes |
| GO:1905521 | regulation of macrophage migration | 66.6667 | 6 | yes |
| GO:1905522 | negative regulation of macrophage migration | 66.6667 | 7 | yes |
| GO:2000145 | regulation of cell motility | 66.6667 | 4 | yes |
| GO:2000146 | negative regulation of cell motility | 66.6667 | 5 | yes |
| GO:2000401 | regulation of lymphocyte migration | 66.6667 | 6 | yes |
| GO:2000402 | negative regulation of lymphocyte migration | 66.6667 | 7 | yes |
| GO:2000404 | regulation of T cell migration | 66.6667 | 7 | yes |
| GO:2000405 | negative regulation of T cell migration | 66.6667 | 8 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 66.6667 | 6 | yes |
| GO:0001817 | regulation of cytokine production | 66.6667 | 4 | yes |
| GO:0001818 | negative regulation of cytokine production | 66.6667 | 5 | yes |
| GO:0001819 | positive regulation of cytokine production | 66.6667 | 5 | yes |
| GO:0002683 | negative regulation of immune system process | 66.6667 | 4 | yes |
| GO:0002685 | regulation of leukocyte migration | 66.6667 | 4 | yes |
| GO:0002686 | negative regulation of leukocyte migration | 66.6667 | 5 | yes |
| GO:0002694 | regulation of leukocyte activation | 66.6667 | 4 | yes |
| GO:0002695 | negative regulation of leukocyte activation | 66.6667 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 66.6667 | 7 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 66.6667 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 66.6667 | 4 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 66.6667 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 66.6667 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 66.6667 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 66.6667 | 4 | yes |
| GO:0010468 | regulation of gene expression | 66.6667 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 66.6667 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 66.6667 | 6 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 66.6667 | 6 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 66.6667 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 66.6667 | 5 | yes |
| GO:0010628 | positive regulation of gene expression | 66.6667 | 7 | yes |
| GO:0010629 | negative regulation of gene expression | 66.6667 | 7 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 66.6667 | 5 | yes |
| GO:0030334 | regulation of cell migration | 66.6667 | 5 | yes |
| GO:0030336 | negative regulation of cell migration | 66.6667 | 6 | yes |
| GO:0031323 | regulation of cellular metabolic process | 66.6667 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 66.6667 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 66.6667 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 66.6667 | 5 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 66.6667 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 66.6667 | 6 | yes |
| GO:0031347 | regulation of defense response | 66.6667 | 5 | yes |
| GO:0031348 | negative regulation of defense response | 66.6667 | 5 | yes |
| GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 66.6667 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 66.6667 | 4 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 66.6667 | 5 | yes |
| GO:0032675 | regulation of interleukin-6 production | 66.6667 | 5 | yes |
| GO:0032715 | negative regulation of interleukin-6 production | 66.6667 | 6 | yes |
| GO:0032793 | positive regulation of CREB transcription factor activity | 66.6667 | 5 | yes |
| GO:0032880 | regulation of protein localization | 66.6667 | 5 | yes |
| GO:0034113 | heterotypic cell-cell adhesion | 66.6667 | 4 | yes |
| GO:0040013 | negative regulation of locomotion | 66.6667 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 66.6667 | 4 | yes |
| GO:0043030 | regulation of macrophage activation | 66.6667 | 5 | yes |
| GO:0043031 | negative regulation of macrophage activation | 66.6667 | 6 | yes |
| GO:0043085 | positive regulation of catalytic activity | 66.6667 | 4 | yes |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | 66.6667 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MO2R1_HUMAN | [view interactions] | Low throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HUS1_HUMAN | [view interactions] | High throughput | no | yes |
| OX2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A4_HUMAN | [view interactions] | High throughput | no | yes |
| ORC4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC7_HUMAN | [view interactions] | High throughput | no | yes |