SH2D5_HUMAN
May be involved in synaptic plasticity regulation through the control of Rac-GTP levels. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SH2D5_HUMAN |
---|---|---|---|---|
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 40.0000 | 4 | no |
GO:0004713 | protein tyrosine kinase activity | 40.0000 | 4 | no |
GO:0005524 | ATP binding | 40.0000 | 5 | no |
GO:0016301 | kinase activity | 40.0000 | 4 | no |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 40.0000 | 4 | no |
GO:0017076 | purine nucleotide binding | 40.0000 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 40.0000 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 40.0000 | 4 | no |
GO:0032559 | adenyl ribonucleotide binding | 40.0000 | 5 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 40.0000 | 4 | no |
GO:0019902 | phosphatase binding | 40.0000 | 4 | no |
GO:0019903 | protein phosphatase binding | 40.0000 | 5 | no |
GO:0003723 | RNA binding | 40.0000 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SH2D5_HUMAN |
---|---|---|---|---|
GO:0009966 | regulation of signal transduction | 80.0000 | 4 | no |
GO:0010646 | regulation of cell communication | 80.0000 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 80.0000 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 60.0000 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 60.0000 | 4 | no |
GO:0043087 | regulation of GTPase activity | 60.0000 | 5 | no |
GO:0048523 | negative regulation of cellular process | 60.0000 | 4 | no |
GO:0051049 | regulation of transport | 60.0000 | 4 | no |
GO:0051050 | positive regulation of transport | 60.0000 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 60.0000 | 4 | no |
GO:0051336 | regulation of hydrolase activity | 60.0000 | 4 | no |
GO:0071310 | cellular response to organic substance | 60.0000 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 60.0000 | 4 | no |
GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | no |
GO:0051128 | regulation of cellular component organization | 60.0000 | 4 | no |
GO:0002683 | negative regulation of immune system process | 40.0000 | 4 | no |
GO:0002694 | regulation of leukocyte activation | 40.0000 | 4 | no |
GO:0002695 | negative regulation of leukocyte activation | 40.0000 | 5 | no |
GO:0006468 | protein phosphorylation | 40.0000 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 40.0000 | 4 | no |
GO:0006996 | organelle organization | 40.0000 | 4 | no |
GO:0007010 | cytoskeleton organization | 40.0000 | 5 | no |
GO:0007264 | small GTPase mediated signal transduction | 40.0000 | 4 | no |
GO:0008104 | protein localization | 40.0000 | 4 | no |
GO:0016310 | phosphorylation | 40.0000 | 5 | no |
GO:0030334 | regulation of cell migration | 40.0000 | 5 | no |
GO:0034330 | cell junction organization | 40.0000 | 4 | no |
GO:0036211 | protein modification process | 40.0000 | 4 | no |
GO:0043085 | positive regulation of catalytic activity | 40.0000 | 4 | no |
GO:0043412 | macromolecule modification | 40.0000 | 4 | no |
GO:0043547 | positive regulation of GTPase activity | 40.0000 | 6 | no |
GO:0046578 | regulation of Ras protein signal transduction | 40.0000 | 7 | no |
GO:0050865 | regulation of cell activation | 40.0000 | 4 | no |
GO:0050866 | negative regulation of cell activation | 40.0000 | 5 | no |
GO:0051056 | regulation of small GTPase mediated signal transduction | 40.0000 | 6 | no |
GO:0051093 | negative regulation of developmental process | 40.0000 | 4 | no |
GO:0051241 | negative regulation of multicellular organismal process | 40.0000 | 4 | no |
GO:0051345 | positive regulation of hydrolase activity | 40.0000 | 5 | no |
GO:0051726 | regulation of cell cycle | 40.0000 | 4 | no |
GO:0060627 | regulation of vesicle-mediated transport | 40.0000 | 4 | no |
GO:2000145 | regulation of cell motility | 40.0000 | 4 | no |
GO:2000377 | regulation of reactive oxygen species metabolic process | 40.0000 | 5 | no |
GO:0007162 | negative regulation of cell adhesion | 40.0000 | 5 | no |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 40.0000 | 4 | no |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 40.0000 | 5 | no |
GO:0010468 | regulation of gene expression | 40.0000 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
GO:0010628 | positive regulation of gene expression | 40.0000 | 6 | no |
GO:0022407 | regulation of cell-cell adhesion | 40.0000 | 5 | no |
GO:0022408 | negative regulation of cell-cell adhesion | 40.0000 | 6 | no |
GO:0030155 | regulation of cell adhesion | 40.0000 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 40.0000 | 5 | no |
GO:0032386 | regulation of intracellular transport | 40.0000 | 5 | no |
GO:0032388 | positive regulation of intracellular transport | 40.0000 | 5 | no |
GO:0032880 | regulation of protein localization | 40.0000 | 5 | no |
GO:0043408 | regulation of MAPK cascade | 40.0000 | 6 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 40.0000 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 40.0000 | 6 | no |
GO:0060255 | regulation of macromolecule metabolic process | 40.0000 | 4 | no |
GO:0060341 | regulation of cellular localization | 40.0000 | 4 | no |
GO:0070848 | response to growth factor | 40.0000 | 4 | no |
GO:0071363 | cellular response to growth factor stimulus | 40.0000 | 5 | no |
GO:0080090 | regulation of primary metabolic process | 40.0000 | 4 | no |
GO:1903829 | positive regulation of protein localization | 40.0000 | 5 | no |
GO:0008064 | regulation of actin polymerization or depolymerization | 40.0000 | 6 | no |
GO:0030832 | regulation of actin filament length | 40.0000 | 5 | no |
GO:0030833 | regulation of actin filament polymerization | 40.0000 | 7 | no |
GO:0032271 | regulation of protein polymerization | 40.0000 | 6 | no |
GO:0032535 | regulation of cellular component size | 40.0000 | 4 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 40.0000 | 5 | no |
GO:0032970 | regulation of actin filament-based process | 40.0000 | 4 | no |
GO:0033043 | regulation of organelle organization | 40.0000 | 5 | no |
GO:0043254 | regulation of protein-containing complex assembly | 40.0000 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 40.0000 | 4 | no |
GO:0051493 | regulation of cytoskeleton organization | 40.0000 | 6 | no |
GO:0110053 | regulation of actin filament organization | 40.0000 | 6 | no |
GO:1902903 | regulation of supramolecular fiber organization | 40.0000 | 5 | no |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
BCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDZ1P_HUMAN | [view interactions] | High throughput | no | no |
NHRF3_HUMAN | [view interactions] | High throughput | no | no |
RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |