LRRK2_HUMAN

GO
G2C
SynGO
SynaptomeDB

HPA (protein expression in neurons)

Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S007
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 20642453
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S007
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 20642453
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21390248
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21390248
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-293
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 20642453
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: mouse-brain
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 21390248
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-brain
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 21390248
Interaction type: association
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: multidimensional protein identification technology
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: multidimensional protein identification technology
PMID: 23075850
Interaction type: association
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-sh_sy5y
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 24947832
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: far western blotting
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 24351927
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-293t
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 20642453
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: tag visualisation
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: competitor
Participant detection method: tag visualisation
PMID: 24351927
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: tag visualisation
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: tag visualisation
PMID: 24351927
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: tag visualisation
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: tag visualisation
PMID: 24351927
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: affinity chromatography technology
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: affinity chromatography technology
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: neutral component
Biological role participant: competitor
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: affinity chromatography technology
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 21390248
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: surface plasmon resonance
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 24351927
Interaction type: direct interaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61982
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-astrocyte
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q5S006
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 31046837
Interaction type: association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 24351927
Interaction type: direct interaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P61983
Taxonomy: rat
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 24351927
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: unspecified role
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: unspecified role
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: fluorescence polarization spectroscopy
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: -
Interaction detection method: isothermal titration calorimetry
Source: Intact
Original protein 2: Q5S007
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 28202711
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P61981
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: -
Source: STRING [LRRK2_HUMAN] [1433G_HUMAN]
Original protein 2: Q5S007
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: -
Interaction type: -
Evidence: Computational