BACE1_HUMAN

GO
G2C
SynGO
SynaptomeDB

HPA (protein expression in neurons)

Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: P56817
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 19251705
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: P56817
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 28869759
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: P56817
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 31996371
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: yeasx
Interaction detection method: two hybrid
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 12901838
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: human-293
Interaction detection method: fluorescent resonance energy transfer
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 30538620
Interaction type: proximity
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: human-293
Interaction detection method: fluorescent resonance energy transfer
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 30538620
Interaction type: proximity
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: human-293
Interaction detection method: fluorescent resonance energy transfer
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 30538620
Interaction type: proximity
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
Host: mouse-neuro_2_a
Interaction detection method: fluorescent resonance energy transfer
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: tag visualisation by fluorescence
PMID: 30538620
Interaction type: proximity
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
Host: human-293
Interaction detection method: fluorescence microscopy
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunostaining
PMID: 10531052
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: yeasx
Interaction detection method: two hybrid array
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 32814053
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: yeasx
Interaction detection method: two hybrid pooling approach
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 32814053
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: predetermined participant
Host: -
Interaction detection method: protease assay
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 10531052
Interaction type: protein cleavage
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: unspecified role
Biological role participant: enzyme target
Participant detection method: predetermined participant
Host: -
Interaction detection method: protease assay
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: unspecified role
Biological role participant: enzyme
Participant detection method: predetermined participant
PMID: 10677483
Interaction type: protein cleavage
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunocytochemistry
Host: human-hela
Interaction detection method: confocal microscopy
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: immunocytochemistry
PMID: 10677483
Interaction type: colocalization
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: P12023
Taxonomy: mouse
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: western blot
Host: -
Interaction detection method: cosedimentation through density gradient
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 25957769
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme target
Participant detection method: sequence tag identification
Host: -
Interaction detection method: cleavage assay
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: enzyme
Participant detection method: sequence tag identification
PMID: 22801501
Interaction type: cleavage reaction
Evidence: LT
Inferred: -
Original protein 1: P05067
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
Host: yeasx
Interaction detection method: validated two hybrid
Source: Intact
Original protein 2: P56817
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: predetermined participant
PMID: 32814053
Interaction type: physical association
Evidence: HT