OPTN_HUMAN

GO
G2C
SynGO
SynaptomeDB

HPA (protein expression in neurons)

Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: two hybrid
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 18307994
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: two hybrid
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 23414517
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21903422
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21903422
Interaction type: physical association
Evidence: HT
Inferred: from orthologous proteins
Original protein 1: Q8K3K8
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9WUN2
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21862579
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 20174559
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 20174559
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 25803835
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9WUN2
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 26376340
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 26365381
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27035970
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27538435
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27620379
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 30327196
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: affinity chromatography technology
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 31723608
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21903422
Interaction type: direct interaction
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 25803835
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27035970
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: pull down
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K3K8
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: Q9WUN2
Taxonomy: mouse
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 21862579
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 26365381
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 25923723
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: enzymatic study
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27035970
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27620379
Interaction type: association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: imaging technique
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 20174559
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: imaging technique
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 25923723
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: imaging technique
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 27620379
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: imaging technique
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 32556086
Interaction type: colocalization
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: bioid
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 31723608
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: bioid
Source: Biogrid
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: 29395067
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-il-1r
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-293
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 21903422
Interaction type: association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-293
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 21903422
Interaction type: association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-293t
Interaction detection method: anti tag coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 25803835
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: human-il-1r
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 18307994
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 25803835
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: anti tag western blot
Host: -
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: anti tag western blot
PMID: 25803835
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: sequence tag identification
Host: human-Flp-In T-REx 293
Interaction detection method: pull down
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: sequence tag identification
PMID: 32707033
Interaction type: association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
Host: human-293
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 27086836
Interaction type: physical association
Evidence: LT
Inferred: from orthologous proteins
Original protein 1: Q8K3K8
Taxonomy: mouse
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: western blot
Host: mouse-bmdm
Interaction detection method: anti bait coimmunoprecipitation
Source: Intact
Original protein 2: Q9WUN2
Taxonomy: mouse
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: western blot
PMID: 27086836
Interaction type: physical association
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: bait
Biological role participant: unspecified role
Participant detection method: nucleotide sequence identification
Host: yeast
Interaction detection method: two hybrid fragment pooling approach
Source: Intact
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: prey
Biological role participant: unspecified role
Participant detection method: nucleotide sequence identification
PMID: 23414517
Interaction type: physical association
Evidence: HT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
Host: -
Interaction detection method: x-ray crystallography
Source: PDB
Original protein 2: Q9UHD2
Taxonomy: human
Experimental role: neutral component
Biological role participant: unspecified role
Participant detection method: -
PMID: 27620379
Interaction type: direct interaction
Evidence: LT
Inferred: -
Original protein 1: Q96CV9
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
Host: -
Interaction detection method: -
Source: STRING [TBK1_HUMAN] [OPTN_HUMAN]
Original protein 2: Q9UHD2
Taxonomy: -
Experimental role: -
Biological role participant: -
Participant detection method: -
PMID: -
Interaction type: -
Evidence: Computational