TBK1_HUMAN
Evidence for PS localization
Functions
Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as DDX3X (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). This activity allows subsequent homodimerization and nuclear translocation of the IRFs leading to transcriptional activation of pro-inflammatory and antiviral genes including IFNA and IFNB (PubMed, PubMed, PubMed, PubMed). In order to establish such an antiviral state, TBK1 form several different complexes whose composition depends on the type of cell and cellular stimuli (PubMed, PubMed, PubMed). Plays a key role in IRF3 activation: acts by first phosphorylating innate adapter proteins MAVS, STING1 and TICAM1 on their pLxIS motif, leading to recruitment of IRF3, thereby licensing IRF3 for phosphorylation by TBK1 (PubMed, PubMed). Phosphorylated IRF3 dissociates from the adapter proteins, dimerizes, and then enters the nucleus to induce expression of interferons (PubMed). Thus, several scaffolding molecules including FADD, TRADD, MAVS, AZI2, TANK or TBKBP1/SINTBAD can be recruited to the TBK1-containing-complexes (PubMed). Under particular conditions, functions as a NF-kappa-B effector by phosphorylating NF-kappa-B inhibitor alpha/NFKBIA, IKBKB or RELA to translocate NF-Kappa-B to the nucleus (PubMed, PubMed). Restricts bacterial proliferation by phosphorylating the autophagy receptor OPTN/Optineurin on Ser-177, thus enhancing LC3 binding affinity and antibacterial autophagy (PubMed). Phosphorylates SMCR8 component of the C9orf72-SMCR8 complex, promoting autophagosome maturation (PubMed). Phosphorylates and activates AKT1 (PubMed). Seems to play a role in energy balance regulation by sustaining a state of chronic, low-grade inflammation in obesity, wich leads to a negative impact on insulin sensitivity . Attenuates retroviral budding by phosphorylating the endosomal sorting complex required for transport-I (ESCRT-I) subunit VPS37C (PubMed). Phosphorylates Borna disease virus (BDV) P protein (PubMed). Plays an essential role in the TLR3- and IFN-dependent control of herpes virus HSV-1 and HSV-2 infections in the central nervous system (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TBK1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 29.8387 | 4 | yes |
| GO:0003723 | RNA binding | 29.8387 | 4 | no |
| GO:0000166 | nucleotide binding | 28.2258 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 28.2258 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 27.4194 | 6 | yes |
| GO:0032555 | purine ribonucleotide binding | 25.8065 | 4 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | yes |
| GO:0005524 | ATP binding | 24.1935 | 5 | yes |
| GO:0043169 | cation binding | 21.7742 | 4 | no |
| GO:0046872 | metal ion binding | 21.7742 | 5 | no |
| GO:0016301 | kinase activity | 8.8710 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 8.8710 | 4 | yes |
| GO:0019902 | phosphatase binding | 7.2581 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 6.4516 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 6.4516 | 5 | yes |
| GO:0106310 | protein serine kinase activity | 6.4516 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TBK1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.0968 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 59.6774 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 56.4516 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 55.6452 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 49.1935 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.9677 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 45.9677 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 45.9677 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 45.9677 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 45.9677 | 4 | yes |
| GO:0010646 | regulation of cell communication | 41.9355 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 41.9355 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 39.5161 | 5 | yes |
| GO:0010468 | regulation of gene expression | 38.7097 | 6 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 37.0968 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 37.0968 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 36.2903 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 36.2903 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 36.2903 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 35.4839 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 34.6774 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.8710 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 31.4516 | 5 | yes |
| GO:0022607 | cellular component assembly | 31.4516 | 4 | no |
| GO:0008104 | protein localization | 30.6452 | 4 | no |
| GO:0006996 | organelle organization | 29.8387 | 4 | no |
| GO:0043412 | macromolecule modification | 29.0323 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 29.0323 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 29.0323 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 28.2258 | 4 | yes |
| GO:0036211 | protein modification process | 28.2258 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 28.2258 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 27.4194 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 27.4194 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 27.4194 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 26.6129 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 25.8065 | 6 | yes |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 24.1935 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 24.1935 | 6 | yes |
| GO:0071702 | organic substance transport | 24.1935 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.1935 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 24.1935 | 5 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 23.3871 | 6 | yes |
| GO:0032880 | regulation of protein localization | 23.3871 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.3871 | 7 | yes |
| GO:0009967 | positive regulation of signal transduction | 22.5806 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 22.5806 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 22.5806 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 22.5806 | 5 | no |
| GO:0071705 | nitrogen compound transport | 22.5806 | 4 | no |
| GO:0080134 | regulation of response to stress | 21.7742 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 21.7742 | 5 | no |
| GO:0051049 | regulation of transport | 21.7742 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 20.1613 | 7 | yes |
| GO:0042325 | regulation of phosphorylation | 20.1613 | 7 | yes |
| GO:0048585 | negative regulation of response to stimulus | 20.1613 | 4 | yes |
| GO:0015031 | protein transport | 20.1613 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 20.1613 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 19.3548 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 19.3548 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 19.3548 | 7 | yes |
| GO:0009968 | negative regulation of signal transduction | 18.5484 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 18.5484 | 7 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 18.5484 | 6 | yes |
| GO:0009896 | positive regulation of catabolic process | 18.5484 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 17.7419 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 17.7419 | 6 | yes |
| GO:0032101 | regulation of response to external stimulus | 16.9355 | 4 | yes |
| GO:0010629 | negative regulation of gene expression | 16.1290 | 7 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 16.1290 | 8 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 16.1290 | 7 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 16.1290 | 8 | yes |
| GO:0050776 | regulation of immune response | 15.3226 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 15.3226 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 14.5161 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 14.5161 | 5 | yes |
| GO:0042327 | positive regulation of phosphorylation | 14.5161 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 14.5161 | 7 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 14.5161 | 8 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 14.5161 | 4 | yes |
| GO:0010506 | regulation of autophagy | 13.7097 | 6 | yes |
| GO:0031347 | regulation of defense response | 13.7097 | 5 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 13.7097 | 5 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 13.7097 | 9 | yes |
| GO:0140546 | defense response to symbiont | 12.9032 | 4 | yes |
| GO:0141124 | intracellular signaling cassette | 12.9032 | 4 | yes |
| GO:0001817 | regulation of cytokine production | 12.9032 | 4 | yes |
| GO:0050778 | positive regulation of immune response | 12.0968 | 5 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 12.0968 | 6 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 12.0968 | 4 | yes |
| GO:0018193 | peptidyl-amino acid modification | 11.2903 | 5 | yes |
| GO:0045088 | regulation of innate immune response | 11.2903 | 5 | yes |
| GO:0031349 | positive regulation of defense response | 10.4839 | 5 | yes |
| GO:0001819 | positive regulation of cytokine production | 10.4839 | 5 | yes |
| GO:0002833 | positive regulation of response to biotic stimulus | 10.4839 | 5 | yes |
| GO:0016310 | phosphorylation | 9.6774 | 5 | yes |
| GO:0045089 | positive regulation of innate immune response | 9.6774 | 6 | yes |
| GO:0006468 | protein phosphorylation | 9.6774 | 5 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 8.0645 | 6 | yes |
| GO:0032479 | regulation of type I interferon production | 8.0645 | 5 | yes |
| GO:0016241 | regulation of macroautophagy | 7.2581 | 7 | yes |
| GO:0019221 | cytokine-mediated signaling pathway | 7.2581 | 4 | yes |
| GO:0032006 | regulation of TOR signaling | 7.2581 | 6 | yes |
| GO:0043122 | regulation of canonical NF-kappaB signal transduction | 7.2581 | 6 | yes |
| GO:1903432 | regulation of TORC1 signaling | 7.2581 | 7 | yes |
| GO:0010508 | positive regulation of autophagy | 6.4516 | 7 | yes |
| GO:0032481 | positive regulation of type I interferon production | 6.4516 | 6 | yes |
| GO:0043123 | positive regulation of canonical NF-kappaB signal transduction | 6.4516 | 7 | yes |
| GO:0051607 | defense response to virus | 6.4516 | 4 | yes |
| GO:0002758 | innate immune response-activating signaling pathway | 6.4516 | 4 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 5.6452 | 6 | yes |
| GO:0018209 | peptidyl-serine modification | 5.6452 | 6 | yes |
| GO:0002221 | pattern recognition receptor signaling pathway | 5.6452 | 5 | yes |
| GO:0006954 | inflammatory response | 5.6452 | 4 | yes |
| GO:0032008 | positive regulation of TOR signaling | 4.8387 | 7 | yes |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 4.8387 | 8 | yes |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 4.8387 | 9 | yes |
| GO:0060759 | regulation of response to cytokine stimulus | 4.8387 | 4 | yes |
| GO:1904263 | positive regulation of TORC1 signaling | 4.8387 | 8 | yes |
| GO:0001959 | regulation of cytokine-mediated signaling pathway | 4.8387 | 5 | yes |
| GO:0007249 | canonical NF-kappaB signal transduction | 4.8387 | 5 | yes |
| GO:0032648 | regulation of interferon-beta production | 4.0323 | 6 | yes |
| GO:0140888 | interferon-mediated signaling pathway | 4.0323 | 5 | yes |
| GO:0002753 | cytoplasmic pattern recognition receptor signaling pathway | 4.0323 | 4 | yes |
| GO:0016239 | positive regulation of macroautophagy | 3.2258 | 8 | yes |
| GO:0018107 | peptidyl-threonine phosphorylation | 3.2258 | 6 | yes |
| GO:0018210 | peptidyl-threonine modification | 3.2258 | 6 | yes |
| GO:0032007 | negative regulation of TOR signaling | 3.2258 | 7 | yes |
| GO:0032647 | regulation of interferon-alpha production | 3.2258 | 6 | yes |
| GO:0032727 | positive regulation of interferon-alpha production | 3.2258 | 7 | yes |
| GO:0032728 | positive regulation of interferon-beta production | 3.2258 | 7 | yes |
| GO:0032943 | mononuclear cell proliferation | 3.2258 | 4 | yes |
| GO:0060337 | type I interferon-mediated signaling pathway | 3.2258 | 6 | yes |
| GO:1904262 | negative regulation of TORC1 signaling | 3.2258 | 8 | yes |
| GO:0044565 | dendritic cell proliferation | 2.4194 | 5 | yes |
| GO:0060338 | regulation of type I interferon-mediated signaling pathway | 2.4194 | 6 | yes |
| GO:0060760 | positive regulation of response to cytokine stimulus | 2.4194 | 5 | yes |
| GO:0140374 | antiviral innate immune response | 2.4194 | 4 | yes |
| GO:0001961 | positive regulation of cytokine-mediated signaling pathway | 2.4194 | 6 | yes |
| GO:0042742 | defense response to bacterium | 1.6129 | 4 | yes |
| GO:0050830 | defense response to Gram-positive bacterium | 1.6129 | 5 | yes |
| GO:0060340 | positive regulation of type I interferon-mediated signaling pathway | 1.6129 | 7 | yes |
| GO:1904415 | regulation of xenophagy | 1.6129 | 5 | yes |
| GO:1904417 | positive regulation of xenophagy | 1.6129 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ZBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDX41_HUMAN | [view interactions] | Low throughput | no | yes |
| ICOS_HUMAN | [view interactions] | Low throughput | no | no |
| TTC4_HUMAN | [view interactions] | Low throughput | no | yes |
| T3JAM_HUMAN | [view interactions] | Low throughput | no | no |
| XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
| CI072_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | Low throughput | no | yes |
| CEP63_HUMAN | [view interactions] | Low throughput | no | yes |
| TNAP3_HUMAN | [view interactions] | Low throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | Low throughput | no | yes |
| PBIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOA2_HUMAN | [view interactions] | Low throughput | no | no |
| NALP4_HUMAN | [view interactions] | Low throughput | no | no |
| DTX4_HUMAN | [view interactions] | Low throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAIP_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI27_HUMAN | [view interactions] | Low throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RNF11_HUMAN | [view interactions] | Low throughput | no | yes |
| CIKS_HUMAN | [view interactions] | Low throughput | no | yes |
| RIGI_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI11_HUMAN | [view interactions] | Low throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SOCS3_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| PELI1_HUMAN | [view interactions] | Low throughput | no | yes |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| TRI26_HUMAN | [view interactions] | Low throughput | no | yes |
| DYRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI14_HUMAN | [view interactions] | Low throughput | no | yes |
| CTBL1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RN128_HUMAN | [view interactions] | Low throughput | no | yes |
| HERP1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF5_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI23_HUMAN | [view interactions] | Low throughput | no | yes |
| YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| WDR48_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| ZC12A_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| R144B_HUMAN | [view interactions] | Low throughput | no | yes |
| TFG_HUMAN | [view interactions] | Low throughput | no | yes |
| NACC1_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMF1_HUMAN | [view interactions] | Low throughput | no | yes |
| SC16A_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE2S_HUMAN | [view interactions] | Low throughput | no | no |
| UBP15_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | Low throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PPM1B_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TANK_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF7_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC20_HUMAN | [view interactions] | Low throughput | no | no |
| DAPK3_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP19_HUMAN | [view interactions] | Low throughput | no | no |
| TBKB1_HUMAN | [view interactions] | Low throughput | no | no |
| OPTN_HUMAN | [view interactions] | Low throughput | no | yes |
| RN19A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| M4K1_HUMAN | [view interactions] | Low throughput | no | no |
| RBCC1_HUMAN | [view interactions] | Low throughput | no | no |
| IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI46_HUMAN | [view interactions] | Low throughput | no | no |
| TCAM1_HUMAN | [view interactions] | Low throughput | no | yes |
| STAT6_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP24_HUMAN | [view interactions] | Low throughput | no | yes |
| CACO2_HUMAN | [view interactions] | Low throughput | no | yes |
| AZI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STING_HUMAN | [view interactions] | Low throughput | no | yes |
| MIB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MSRE_HUMAN | [view interactions] | Low throughput | no | no |
| MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
| IKKE_HUMAN | [view interactions] | Low throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRF1_HUMAN | [view interactions] | Low throughput | no | yes |
| MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| TXLNA_HUMAN | [view interactions] | Low throughput | no | yes |
| SMCR8_HUMAN | [view interactions] | Low throughput | no | yes |
| RO52_HUMAN | [view interactions] | Low throughput | no | yes |
| MIB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RIPK1_HUMAN | [view interactions] | Low throughput | no | yes |
| M3K14_HUMAN | [view interactions] | Low throughput | no | yes |
| CRTC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | Low throughput | no | no |
| LMO7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RIOK3_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF5_HUMAN | [view interactions] | Low throughput | no | no |
| LEG3_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| TXLNB_HUMAN | [view interactions] | High throughput | no | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| BODG_HUMAN | [view interactions] | High throughput | no | no |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3B_HUMAN | [view interactions] | High throughput | no | no |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| PATL1_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OBI1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAG2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| RARA_HUMAN | [view interactions] | High throughput | no | no |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PXK_HUMAN | [view interactions] | High throughput | no | yes |
| DPCD_HUMAN | [view interactions] | High throughput | no | yes |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA3_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6A_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6C_HUMAN | [view interactions] | High throughput | no | no |
| TTP_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| DCP1A_HUMAN | [view interactions] | High throughput | no | yes |
| ABR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARF1_HUMAN | [view interactions] | High throughput | no | yes |
| CASL_HUMAN | [view interactions] | High throughput | no | yes |
| RN214_HUMAN | [view interactions] | High throughput | no | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXJ3_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| FMNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K4_HUMAN | [view interactions] | High throughput | no | yes |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OSBL3_HUMAN | [view interactions] | High throughput | no | yes |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PF21A_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| NUP98_HUMAN | [view interactions] | High throughput | no | no |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| DCTN5_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOB_HUMAN | [view interactions] | High throughput | no | no |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| ARGI1_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| NCOA5_HUMAN | [view interactions] | High throughput | no | yes |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| HMGA1_HUMAN | [view interactions] | High throughput | no | yes |
| RLA0L_HUMAN | [view interactions] | High throughput | no | no |
| HMGN2_HUMAN | [view interactions] | High throughput | no | no |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASCC2_HUMAN | [view interactions] | High throughput | no | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C9_HUMAN | [view interactions] | High throughput | no | no |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCOF_HUMAN | [view interactions] | High throughput | no | yes |
| ATRX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA3D_HUMAN | [view interactions] | High throughput | no | no |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGFR_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM24_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDF1_HUMAN | [view interactions] | High throughput | no | yes |
| RPC5_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| ATLA3_HUMAN | [view interactions] | High throughput | no | no |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RNZ2_HUMAN | [view interactions] | High throughput | no | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| ICAL_HUMAN | [view interactions] | High throughput | no | yes |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| RNPS1_HUMAN | [view interactions] | High throughput | no | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| MAP7_HUMAN | [view interactions] | High throughput | no | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| NUCKS_HUMAN | [view interactions] | High throughput | no | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| K22E_HUMAN | [view interactions] | High throughput | no | no |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| RALB_HUMAN | [view interactions] | High throughput | no | no |
| ADIP_HUMAN | [view interactions] | High throughput | no | yes |
| MRM3_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| RU1C_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA8_HUMAN | [view interactions] | High throughput | no | no |
| I2BPL_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| SCAM3_HUMAN | [view interactions] | High throughput | no | no |
| WHRN_HUMAN | [view interactions] | High throughput | no | no |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| NKAP_HUMAN | [view interactions] | High throughput | no | yes |
| AGFG1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| MANBL_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| REL_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| TB10B_HUMAN | [view interactions] | High throughput | no | no |
| PP6R2_HUMAN | [view interactions] | High throughput | no | no |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| SR140_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB2_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| LYRM2_HUMAN | [view interactions] | High throughput | no | no |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| MRP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PININ_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| TLR4_HUMAN | [view interactions] | High throughput | no | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| TLR9_HUMAN | [view interactions] | High throughput | no | no |
| ARC1B_HUMAN | [view interactions] | High throughput | no | no |
| TLR3_HUMAN | [view interactions] | High throughput | no | yes |
| K1143_HUMAN | [view interactions] | High throughput | no | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHP14_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSRAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HBA_HUMAN | [view interactions] | High throughput | no | no |
| DDX23_HUMAN | [view interactions] | High throughput | no | yes |
| CP51A_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LC7L3_HUMAN | [view interactions] | High throughput | no | yes |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP1_HUMAN | [view interactions] | High throughput | no | yes |
| TM263_HUMAN | [view interactions] | High throughput | no | yes |
| KSYK_HUMAN | [view interactions] | High throughput | no | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| IPO4_HUMAN | [view interactions] | High throughput | no | no |
| ENAH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| CC124_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTF3_HUMAN | [view interactions] | High throughput | no | yes |
| STX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI10_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIT3_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PHF23_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| PFKAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REN3B_HUMAN | [view interactions] | High throughput | no | yes |
| ARK72_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COP1_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| CLC14_HUMAN | [view interactions] | High throughput | no | yes |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| MYD88_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ULK1_HUMAN | [view interactions] | High throughput | no | no |
| RRAGD_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| PHIP_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LR10B_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| FLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IRAK3_HUMAN | [view interactions] | High throughput | no | yes |
| HVCN1_HUMAN | [view interactions] | High throughput | no | yes |
| PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KR197_HUMAN | [view interactions] | High throughput | no | no |
| S100P_HUMAN | [view interactions] | High throughput | no | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| PIP_HUMAN | [view interactions] | High throughput | no | no |
| NAA10_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| D2HDH_HUMAN | [view interactions] | High throughput | no | no |
| CRBB3_HUMAN | [view interactions] | High throughput | no | no |
| ARL4D_HUMAN | [view interactions] | High throughput | no | no |
| ST1C4_HUMAN | [view interactions] | High throughput | no | no |
| GROA_HUMAN | [view interactions] | High throughput | no | no |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| PROS_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP3_HUMAN | [view interactions] | High throughput | no | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RE114_HUMAN | [view interactions] | High throughput | no | no |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAPD1_HUMAN | [view interactions] | High throughput | no | yes |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| LETM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| ATG10_HUMAN | [view interactions] | High throughput | no | yes |
| MRCKG_HUMAN | [view interactions] | High throughput | no | no |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| HMMR_HUMAN | [view interactions] | High throughput | no | yes |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBBP5_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| TXLNG_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APBA3_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| STX19_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |