TRAF3_HUMAN
Evidence for PS localization
Functions
Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote Lys-63-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 118 | Arg | Trp | Encephalopathy,acute,infection-induced,5,herpes-specific(IIAE5) | - |
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI003831 | MOD_CK1_1 | MOD | 349 | 355 | - |
| ELMI003831 | MOD_CK1_1 | MOD | 349 | 355 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TRAF3_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 35.3659 | 4 | yes |
| GO:0046872 | metal ion binding | 35.3659 | 5 | yes |
| GO:0000166 | nucleotide binding | 26.8293 | 4 | no |
| GO:0043168 | anion binding | 26.8293 | 4 | no |
| GO:0019900 | kinase binding | 24.3902 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 24.3902 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 24.3902 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.3902 | 4 | no |
| GO:0019901 | protein kinase binding | 21.9512 | 5 | yes |
| GO:0005524 | ATP binding | 20.7317 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 20.7317 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.7317 | 5 | no |
| GO:0031625 | ubiquitin protein ligase binding | 19.5122 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 19.5122 | 4 | yes |
| GO:0016755 | aminoacyltransferase activity | 18.2927 | 4 | yes |
| GO:0004842 | ubiquitin-protein transferase activity | 17.0732 | 4 | yes |
| GO:0061630 | ubiquitin protein ligase activity | 14.6341 | 5 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 14.6341 | 4 | yes |
| GO:0008270 | zinc ion binding | 10.9756 | 7 | yes |
| GO:0046914 | transition metal ion binding | 10.9756 | 6 | yes |
| GO:0019902 | phosphatase binding | 8.5366 | 4 | yes |
| GO:0005126 | cytokine receptor binding | 7.3171 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 7.3171 | 5 | yes |
| GO:0032813 | tumor necrosis factor receptor superfamily binding | 6.0976 | 5 | yes |
| GO:0005164 | tumor necrosis factor receptor binding | 4.8780 | 6 | yes |
| GO:0031996 | thioesterase binding | 3.6585 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TRAF3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 59.7561 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 58.5366 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 56.0976 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 53.6585 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 52.4390 | 4 | yes |
| GO:0010646 | regulation of cell communication | 48.7805 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 46.3415 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 43.9024 | 5 | yes |
| GO:0043412 | macromolecule modification | 42.6829 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 42.6829 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 41.4634 | 4 | yes |
| GO:0010468 | regulation of gene expression | 41.4634 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 41.4634 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 41.4634 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 41.4634 | 5 | yes |
| GO:0036211 | protein modification process | 41.4634 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 37.8049 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 35.3659 | 4 | yes |
| GO:0006996 | organelle organization | 34.1463 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.9268 | 5 | yes |
| GO:0008104 | protein localization | 31.7073 | 4 | no |
| GO:0022607 | cellular component assembly | 30.4878 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.4878 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 29.2683 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 29.2683 | 5 | no |
| GO:0023056 | positive regulation of signaling | 29.2683 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.2683 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.2683 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 28.0488 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.0488 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 28.0488 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.8293 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 26.8293 | 4 | yes |
| GO:0043687 | post-translational protein modification | 25.6098 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 25.6098 | 4 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 25.6098 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 25.6098 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.6098 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.6098 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.6098 | 6 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.6098 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.6098 | 6 | yes |
| GO:0009894 | regulation of catabolic process | 24.3902 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.3902 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 24.3902 | 4 | no |
| GO:0031399 | regulation of protein modification process | 24.3902 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 24.3902 | 5 | no |
| GO:0006508 | proteolysis | 23.1707 | 4 | no |
| GO:0051049 | regulation of transport | 23.1707 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.1707 | 4 | no |
| GO:0032446 | protein modification by small protein conjugation | 23.1707 | 7 | yes |
| GO:0051252 | regulation of RNA metabolic process | 21.9512 | 5 | yes |
| GO:0009057 | macromolecule catabolic process | 21.9512 | 4 | no |
| GO:0032880 | regulation of protein localization | 21.9512 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 21.9512 | 7 | yes |
| GO:0016567 | protein ubiquitination | 21.9512 | 8 | yes |
| GO:0080134 | regulation of response to stress | 20.7317 | 4 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 20.7317 | 6 | yes |
| GO:0033043 | regulation of organelle organization | 20.7317 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 20.7317 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 20.7317 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.7317 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.7317 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.7317 | 7 | yes |
| GO:0001817 | regulation of cytokine production | 19.5122 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 18.2927 | 4 | yes |
| GO:0140546 | defense response to symbiont | 15.8537 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 15.8537 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 14.6341 | 6 | yes |
| GO:0031347 | regulation of defense response | 14.6341 | 5 | yes |
| GO:0050776 | regulation of immune response | 13.4146 | 4 | yes |
| GO:0006915 | apoptotic process | 13.4146 | 4 | yes |
| GO:0050778 | positive regulation of immune response | 12.1951 | 5 | yes |
| GO:0000209 | protein polyubiquitination | 12.1951 | 9 | yes |
| GO:0001819 | positive regulation of cytokine production | 10.9756 | 5 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 10.9756 | 5 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 9.7561 | 4 | yes |
| GO:0032479 | regulation of type I interferon production | 9.7561 | 5 | yes |
| GO:0043122 | regulation of canonical NF-kappaB signal transduction | 8.5366 | 6 | yes |
| GO:0045088 | regulation of innate immune response | 8.5366 | 5 | yes |
| GO:0045089 | positive regulation of innate immune response | 8.5366 | 6 | yes |
| GO:0051607 | defense response to virus | 8.5366 | 4 | yes |
| GO:0002833 | positive regulation of response to biotic stimulus | 8.5366 | 5 | yes |
| GO:0019221 | cytokine-mediated signaling pathway | 8.5366 | 4 | yes |
| GO:0031349 | positive regulation of defense response | 8.5366 | 5 | yes |
| GO:0070534 | protein K63-linked ubiquitination | 7.3171 | 10 | yes |
| GO:0002758 | innate immune response-activating signaling pathway | 6.0976 | 4 | yes |
| GO:0032481 | positive regulation of type I interferon production | 6.0976 | 6 | yes |
| GO:0032648 | regulation of interferon-beta production | 6.0976 | 6 | yes |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | 4.8780 | 4 | yes |
| GO:0060337 | type I interferon-mediated signaling pathway | 4.8780 | 6 | yes |
| GO:0140888 | interferon-mediated signaling pathway | 4.8780 | 5 | yes |
| GO:0002221 | pattern recognition receptor signaling pathway | 4.8780 | 5 | yes |
| GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 4.8780 | 5 | yes |
| GO:0050688 | regulation of defense response to virus | 3.6585 | 5 | yes |
| GO:0002224 | toll-like receptor signaling pathway | 3.6585 | 6 | yes |
| GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 3.6585 | 7 | yes |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | 3.6585 | 5 | yes |
| GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 3.6585 | 8 | yes |
| GO:0008063 | Toll signaling pathway | 2.4390 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
| MYSM1_HUMAN | [view interactions] | Low throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASC_HUMAN | [view interactions] | Low throughput | no | no |
| M3K7_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI14_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FOSL1_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OSTP_HUMAN | [view interactions] | Low throughput | no | yes |
| STK38_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| I17RA_HUMAN | [view interactions] | Low throughput | no | yes |
| KAPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| WDR82_HUMAN | [view interactions] | Low throughput | no | no |
| ZC12A_HUMAN | [view interactions] | Low throughput | no | yes |
| U17L2_HUMAN | [view interactions] | Low throughput | no | no |
| DHX58_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP25_HUMAN | [view interactions] | Low throughput | no | yes |
| ABCF1_HUMAN | [view interactions] | Low throughput | no | yes |
| PINK1_HUMAN | [view interactions] | Low throughput | no | yes |
| MSRE_HUMAN | [view interactions] | Low throughput | no | no |
| R144B_HUMAN | [view interactions] | Low throughput | no | yes |
| CRTC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TIF1A_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN6_HUMAN | [view interactions] | Low throughput | no | no |
| BLK_HUMAN | [view interactions] | Low throughput | no | no |
| MFN1_HUMAN | [view interactions] | Low throughput | no | yes |
| FOXO1_HUMAN | [view interactions] | Low throughput | no | yes |
| NED4L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MFF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RN126_HUMAN | [view interactions] | Low throughput | no | yes |
| TIFA_HUMAN | [view interactions] | Low throughput | no | yes |
| ULK1_HUMAN | [view interactions] | Low throughput | no | no |
| CAR19_HUMAN | [view interactions] | Low throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | Low throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR6_HUMAN | [view interactions] | Low throughput | no | no |
| CASP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CELF2_HUMAN | [view interactions] | Low throughput | no | yes |
| HNRPC_HUMAN | [view interactions] | Low throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TRADD_HUMAN | [view interactions] | Low throughput | no | yes |
| RIPK1_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR4_HUMAN | [view interactions] | Low throughput | no | no |
| TNR9_HUMAN | [view interactions] | Low throughput | no | no |
| TNR5_HUMAN | [view interactions] | Low throughput | no | no |
| TNR11_HUMAN | [view interactions] | Low throughput | no | yes |
| MIPT3_HUMAN | [view interactions] | Low throughput | no | yes |
| RIPK2_HUMAN | [view interactions] | Low throughput | no | yes |
| GMEB1_HUMAN | [view interactions] | Low throughput | no | yes |
| EDAR_HUMAN | [view interactions] | Low throughput | no | yes |
| ZMY11_HUMAN | [view interactions] | Low throughput | no | no |
| TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TNR3_HUMAN | [view interactions] | Low throughput | no | yes |
| TANK_HUMAN | [view interactions] | Low throughput | no | yes |
| TLR4_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF5_HUMAN | [view interactions] | Low throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | Low throughput | no | no |
| BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN22_HUMAN | [view interactions] | Low throughput | no | yes |
| M3K14_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR8_HUMAN | [view interactions] | Low throughput | no | no |
| TNR27_HUMAN | [view interactions] | Low throughput | no | no |
| E2AK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRAK1_HUMAN | [view interactions] | Low throughput | no | yes |
| MYD88_HUMAN | [view interactions] | Low throughput | no | yes |
| WDR5_HUMAN | [view interactions] | Low throughput | no | no |
| TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IKKE_HUMAN | [view interactions] | Low throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | Low throughput | no | yes |
| TFG_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR14_HUMAN | [view interactions] | Low throughput | no | no |
| MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
| UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRAF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TCAM1_HUMAN | [view interactions] | Low throughput | no | yes |
| IL1AP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RIGI_HUMAN | [view interactions] | Low throughput | no | yes |
| OTU7B_HUMAN | [view interactions] | Low throughput | no | yes |
| MALT1_HUMAN | [view interactions] | Low throughput | no | no |
| T3JAM_HUMAN | [view interactions] | Low throughput | no | no |
| TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NUP62_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR18_HUMAN | [view interactions] | Low throughput | no | no |
| TNR12_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
| TNF14_HUMAN | [view interactions] | Low throughput | no | yes |
| TYDP2_HUMAN | [view interactions] | Low throughput | no | no |
| CD27_HUMAN | [view interactions] | Low throughput | no | no |
| CFLAR_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR17_HUMAN | [view interactions] | Low throughput | no | no |
| CIKS_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR19_HUMAN | [view interactions] | Low throughput | no | no |
| OTUD5_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAIP_HUMAN | [view interactions] | Low throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | Low throughput | no | yes |
| OTUB2_HUMAN | [view interactions] | Low throughput | no | no |
| RN216_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NLRX1_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
| OPTN_HUMAN | [view interactions] | Low throughput | no | yes |
| CBLB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TNR1B_HUMAN | [view interactions] | Low throughput | no | no |
| TR13C_HUMAN | [view interactions] | Low throughput | no | no |
| TR13B_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
| NF2IP_HUMAN | [view interactions] | Low throughput | no | no |
| PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CANB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STING_HUMAN | [view interactions] | Low throughput | no | yes |
| RN166_HUMAN | [view interactions] | Low throughput | no | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV3_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| CASP2_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| EYA3_HUMAN | [view interactions] | High throughput | no | no |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCKP5_HUMAN | [view interactions] | High throughput | no | no |
| DAZL_HUMAN | [view interactions] | High throughput | no | no |
| KRT38_HUMAN | [view interactions] | High throughput | no | no |
| PCD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECD3_HUMAN | [view interactions] | High throughput | no | yes |
| GSTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCRU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PISD_HUMAN | [view interactions] | High throughput | no | yes |
| S2540_HUMAN | [view interactions] | High throughput | no | no |
| HDHD3_HUMAN | [view interactions] | High throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDS2_HUMAN | [view interactions] | High throughput | no | yes |
| ACBP_HUMAN | [view interactions] | High throughput | no | yes |
| THIC_HUMAN | [view interactions] | High throughput | no | yes |
| RETST_HUMAN | [view interactions] | High throughput | no | yes |
| PDE9A_HUMAN | [view interactions] | High throughput | no | yes |
| S4A7_HUMAN | [view interactions] | High throughput | no | no |
| KGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A1_HUMAN | [view interactions] | High throughput | no | no |
| MAOX_HUMAN | [view interactions] | High throughput | no | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGM2_HUMAN | [view interactions] | High throughput | no | no |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| GSTO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACPH_HUMAN | [view interactions] | High throughput | no | yes |
| SERC_HUMAN | [view interactions] | High throughput | no | yes |
| UGPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCYB1_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PXDC2_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| IL1B_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTK_HUMAN | [view interactions] | High throughput | no | no |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIFCL_HUMAN | [view interactions] | High throughput | no | yes |
| EP15R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAXX_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MRP1_HUMAN | [view interactions] | High throughput | no | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABC3C_HUMAN | [view interactions] | High throughput | no | no |
| H14_HUMAN | [view interactions] | High throughput | no | yes |
| KDSR_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| KPRP_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KRT36_HUMAN | [view interactions] | High throughput | no | no |
| KRT86_HUMAN | [view interactions] | High throughput | no | no |
| IRF1_HUMAN | [view interactions] | High throughput | no | yes |
| KRT81_HUMAN | [view interactions] | High throughput | no | no |
| AZI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRT83_HUMAN | [view interactions] | High throughput | no | no |
| MEF2C_HUMAN | [view interactions] | High throughput | no | yes |
| TLR3_HUMAN | [view interactions] | High throughput | no | yes |
| RT07_HUMAN | [view interactions] | High throughput | no | yes |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |
| TLR9_HUMAN | [view interactions] | High throughput | no | no |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCID2_HUMAN | [view interactions] | High throughput | no | yes |
| PELO_HUMAN | [view interactions] | High throughput | no | yes |
| PGAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB39A_HUMAN | [view interactions] | High throughput | no | no |
| TSKS_HUMAN | [view interactions] | High throughput | no | no |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| SAMC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| S27A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMCA4_HUMAN | [view interactions] | High throughput | no | yes |
| SHPK_HUMAN | [view interactions] | High throughput | no | no |
| SWP70_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TEX30_HUMAN | [view interactions] | High throughput | no | no |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| VCIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPOLA_HUMAN | [view interactions] | High throughput | no | yes |
| ORC3_HUMAN | [view interactions] | High throughput | no | yes |
| CPVL_HUMAN | [view interactions] | High throughput | no | no |
| ASCC3_HUMAN | [view interactions] | High throughput | no | yes |
| DDB2_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP1_HUMAN | [view interactions] | High throughput | no | yes |
| STAG2_HUMAN | [view interactions] | High throughput | no | yes |
| PARP9_HUMAN | [view interactions] | High throughput | no | no |
| NFIL3_HUMAN | [view interactions] | High throughput | no | no |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX60_HUMAN | [view interactions] | High throughput | no | no |
| ETV6_HUMAN | [view interactions] | High throughput | no | no |
| WDR62_HUMAN | [view interactions] | High throughput | no | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| FA53C_HUMAN | [view interactions] | High throughput | no | yes |
| K0232_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IL15_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIVM_HUMAN | [view interactions] | High throughput | no | yes |
| RIPP1_HUMAN | [view interactions] | High throughput | no | no |
| GMEB2_HUMAN | [view interactions] | High throughput | no | yes |
| IFT25_HUMAN | [view interactions] | High throughput | no | yes |
| CJ062_HUMAN | [view interactions] | High throughput | no | no |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CC184_HUMAN | [view interactions] | High throughput | no | no |
| ZBT49_HUMAN | [view interactions] | High throughput | no | yes |
| IP6K3_HUMAN | [view interactions] | High throughput | no | no |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| ZSCA4_HUMAN | [view interactions] | High throughput | no | no |
| CCD13_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDZD4_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS2_HUMAN | [view interactions] | High throughput | no | yes |
| HEMGN_HUMAN | [view interactions] | High throughput | no | no |
| ASCC1_HUMAN | [view interactions] | High throughput | no | yes |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| PSB8_HUMAN | [view interactions] | High throughput | no | yes |
| ZBP1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| GALC_HUMAN | [view interactions] | High throughput | no | yes |
| TROAP_HUMAN | [view interactions] | High throughput | no | yes |
| MYT1_HUMAN | [view interactions] | High throughput | no | yes |
| KSYK_HUMAN | [view interactions] | High throughput | no | no |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
| IFIT3_HUMAN | [view interactions] | High throughput | no | yes |