TRAF3_HUMAN
Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote Lys-63-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Position | Amino acid | Mutation | Disease | Overlap with binding region |
---|---|---|---|---|
118 | Arg | Trp | Encephalopathy,acute,infection-induced,5,herpes-specific(IIAE5) | - |
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI003711 | LIG_SH2_STAP1 | LIG | 482 | 486 | - |
ELMI003831 | MOD_CK1_1 | MOD | 349 | 355 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in TRAF3_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 31.4815 | 4 | yes |
GO:0017076 | purine nucleotide binding | 29.6296 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 29.6296 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 29.6296 | 4 | no |
GO:0019900 | kinase binding | 27.7778 | 4 | yes |
GO:0031625 | ubiquitin protein ligase binding | 27.7778 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 27.7778 | 4 | yes |
GO:0019901 | protein kinase binding | 25.9259 | 5 | yes |
GO:0005524 | ATP binding | 22.2222 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 22.2222 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 22.2222 | 5 | no |
GO:0004842 | ubiquitin-protein transferase activity | 18.5185 | 4 | yes |
GO:0019902 | phosphatase binding | 12.9630 | 4 | yes |
GO:0019903 | protein phosphatase binding | 11.1111 | 5 | yes |
GO:0005126 | cytokine receptor binding | 9.2593 | 4 | yes |
GO:0008270 | zinc ion binding | 9.2593 | 6 | yes |
GO:0046914 | transition metal ion binding | 9.2593 | 5 | yes |
GO:0032813 | tumor necrosis factor receptor superfamily binding | 7.4074 | 5 | yes |
GO:0005164 | tumor necrosis factor receptor binding | 5.5556 | 6 | yes |
GO:0031996 | thioesterase binding | 5.5556 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in TRAF3_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 72.2222 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 70.3704 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 62.9630 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 62.9630 | 4 | yes |
GO:0010646 | regulation of cell communication | 59.2593 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 57.4074 | 4 | yes |
GO:0009966 | regulation of signal transduction | 53.7037 | 4 | yes |
GO:0010468 | regulation of gene expression | 51.8519 | 5 | yes |
GO:0009893 | positive regulation of metabolic process | 51.8519 | 4 | no |
GO:0036211 | protein modification process | 50.0000 | 4 | yes |
GO:0043412 | macromolecule modification | 50.0000 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 50.0000 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
GO:0048523 | negative regulation of cellular process | 48.1481 | 4 | no |
GO:0051128 | regulation of cellular component organization | 44.4444 | 4 | no |
GO:0010647 | positive regulation of cell communication | 44.4444 | 5 | yes |
GO:0023056 | positive regulation of signaling | 44.4444 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 44.4444 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 42.5926 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 40.7407 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 38.8889 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 38.8889 | 5 | no |
GO:0051049 | regulation of transport | 37.0370 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 37.0370 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 37.0370 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 37.0370 | 5 | yes |
GO:0006355 | regulation of DNA-templated transcription | 35.1852 | 6 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 35.1852 | 5 | yes |
GO:0051252 | regulation of RNA metabolic process | 35.1852 | 5 | yes |
GO:1903506 | regulation of nucleic acid-templated transcription | 35.1852 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 35.1852 | 6 | yes |
GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 33.3333 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0051130 | positive regulation of cellular component organization | 31.4815 | 5 | no |
GO:0031399 | regulation of protein modification process | 31.4815 | 6 | no |
GO:0080134 | regulation of response to stress | 31.4815 | 4 | yes |
GO:0060341 | regulation of cellular localization | 29.6296 | 4 | no |
GO:0010941 | regulation of cell death | 29.6296 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 29.6296 | 4 | no |
GO:0008104 | protein localization | 29.6296 | 4 | no |
GO:0010648 | negative regulation of cell communication | 29.6296 | 5 | no |
GO:0023057 | negative regulation of signaling | 29.6296 | 4 | no |
GO:0051050 | positive regulation of transport | 27.7778 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.7778 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 27.7778 | 4 | no |
GO:0051094 | positive regulation of developmental process | 27.7778 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 27.7778 | 6 | no |
GO:0042325 | regulation of phosphorylation | 27.7778 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 27.7778 | 5 | no |
GO:0042981 | regulation of apoptotic process | 27.7778 | 6 | yes |
GO:0043067 | regulation of programmed cell death | 27.7778 | 5 | yes |
GO:0043408 | regulation of MAPK cascade | 27.7778 | 6 | yes |
GO:0070647 | protein modification by small protein conjugation or removal | 27.7778 | 5 | yes |
GO:0032880 | regulation of protein localization | 25.9259 | 5 | no |
GO:0006996 | organelle organization | 25.9259 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 25.9259 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 25.9259 | 7 | no |
GO:0001932 | regulation of protein phosphorylation | 25.9259 | 7 | no |
GO:0051338 | regulation of transferase activity | 25.9259 | 4 | no |
GO:0016567 | protein ubiquitination | 25.9259 | 7 | yes |
GO:0030162 | regulation of proteolysis | 25.9259 | 6 | yes |
GO:0032446 | protein modification by small protein conjugation | 25.9259 | 6 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 25.9259 | 5 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.0741 | 6 | no |
GO:0048585 | negative regulation of response to stimulus | 24.0741 | 4 | no |
GO:0016192 | vesicle-mediated transport | 24.0741 | 4 | no |
GO:0001817 | regulation of cytokine production | 24.0741 | 4 | yes |
GO:0010628 | positive regulation of gene expression | 24.0741 | 6 | no |
GO:0045595 | regulation of cell differentiation | 22.2222 | 4 | no |
GO:0071310 | cellular response to organic substance | 22.2222 | 4 | no |
GO:0006508 | proteolysis | 22.2222 | 4 | no |
GO:0009057 | macromolecule catabolic process | 22.2222 | 4 | no |
GO:0019941 | modification-dependent protein catabolic process | 22.2222 | 6 | no |
GO:0043632 | modification-dependent macromolecule catabolic process | 22.2222 | 5 | no |
GO:0044265 | cellular macromolecule catabolic process | 22.2222 | 4 | no |
GO:0051603 | proteolysis involved in protein catabolic process | 22.2222 | 5 | no |
GO:0033043 | regulation of organelle organization | 22.2222 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 22.2222 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 22.2222 | 4 | no |
GO:0043549 | regulation of kinase activity | 22.2222 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 20.3704 | 6 | no |
GO:0031344 | regulation of cell projection organization | 20.3704 | 5 | no |
GO:0050804 | modulation of chemical synaptic transmission | 20.3704 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 20.3704 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 20.3704 | 6 | no |
GO:0022607 | cellular component assembly | 20.3704 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 20.3704 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 20.3704 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 20.3704 | 7 | no |
GO:0043410 | positive regulation of MAPK cascade | 20.3704 | 7 | yes |
GO:0050776 | regulation of immune response | 20.3704 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 20.3704 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.3704 | 6 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.3704 | 4 | no |
GO:0031347 | regulation of defense response | 18.5185 | 5 | yes |
GO:0032101 | regulation of response to external stimulus | 18.5185 | 4 | yes |
GO:0080135 | regulation of cellular response to stress | 18.5185 | 4 | yes |
GO:0032872 | regulation of stress-activated MAPK cascade | 16.6667 | 6 | yes |
GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 16.6667 | 5 | yes |
GO:0000209 | protein polyubiquitination | 14.8148 | 8 | yes |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 14.8148 | 6 | yes |
GO:0046328 | regulation of JNK cascade | 14.8148 | 7 | yes |
GO:0002831 | regulation of response to biotic stimulus | 12.9630 | 4 | yes |
GO:0006915 | apoptotic process | 12.9630 | 4 | yes |
GO:0032479 | regulation of type I interferon production | 12.9630 | 5 | yes |
GO:0032874 | positive regulation of stress-activated MAPK cascade | 12.9630 | 7 | yes |
GO:0070304 | positive regulation of stress-activated protein kinase signaling cascade | 12.9630 | 6 | yes |
GO:0032648 | regulation of interferon-beta production | 11.1111 | 6 | yes |
GO:0046330 | positive regulation of JNK cascade | 11.1111 | 8 | yes |
GO:0070534 | protein K63-linked ubiquitination | 11.1111 | 9 | yes |
GO:0019221 | cytokine-mediated signaling pathway | 9.2593 | 4 | yes |
GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 7.4074 | 5 | yes |
GO:0043433 | negative regulation of DNA-binding transcription factor activity | 7.4074 | 4 | yes |
GO:0002221 | pattern recognition receptor signaling pathway | 5.5556 | 4 | yes |
GO:0002224 | toll-like receptor signaling pathway | 5.5556 | 5 | yes |
GO:0008063 | Toll signaling pathway | 5.5556 | 4 | yes |
GO:0050688 | regulation of defense response to virus | 5.5556 | 5 | yes |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 3.7037 | 6 | yes |
GO:0033209 | tumor necrosis factor-mediated signaling pathway | 3.7037 | 5 | yes |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 3.7037 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in TRAF3_HUMAN |
---|---|---|---|---|
DOID:331 | central nervous system disease | 5.5556 | 3 | no |
DOID:1289 | neurodegenerative disease | 3.7037 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
TRAIP_HUMAN | [view interactions] | Low throughput | no | yes |
OTUB1_HUMAN | [view interactions] | Low throughput | no | yes |
OTUB2_HUMAN | [view interactions] | Low throughput | no | no |
RN216_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NLRX1_HUMAN | [view interactions] | Low throughput | no | yes |
RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
OPTN_HUMAN | [view interactions] | Low throughput | no | yes |
CBLB_HUMAN | [view interactions] | Low throughput | no | yes |
TNR1B_HUMAN | [view interactions] | Low throughput | no | no |
TR13C_HUMAN | [view interactions] | Low throughput | no | no |
TR13B_HUMAN | [view interactions] | Low throughput | no | yes |
IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
NF2IP_HUMAN | [view interactions] | Low throughput | no | no |
PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CANB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TFG_HUMAN | [view interactions] | Low throughput | no | yes |
UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STING_HUMAN | [view interactions] | Low throughput | no | yes |
RN166_HUMAN | [view interactions] | Low throughput | no | no |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
MYSM1_HUMAN | [view interactions] | Low throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ASC_HUMAN | [view interactions] | Low throughput | no | no |
M3K7_HUMAN | [view interactions] | Low throughput | no | yes |
TRI14_HUMAN | [view interactions] | Low throughput | no | yes |
KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FOSL1_HUMAN | [view interactions] | Low throughput | no | yes |
DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
OSTP_HUMAN | [view interactions] | Low throughput | no | yes |
STK38_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
I17RA_HUMAN | [view interactions] | Low throughput | no | yes |
KAPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP1_HUMAN | [view interactions] | Low throughput | no | yes |
WDR82_HUMAN | [view interactions] | Low throughput | no | no |
ZC12A_HUMAN | [view interactions] | Low throughput | no | yes |
U17L2_HUMAN | [view interactions] | Low throughput | no | no |
DHX58_HUMAN | [view interactions] | Low throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP25_HUMAN | [view interactions] | Low throughput | no | yes |
ABCF1_HUMAN | [view interactions] | Low throughput | no | yes |
PINK1_HUMAN | [view interactions] | Low throughput | no | yes |
MSRE_HUMAN | [view interactions] | Low throughput | no | no |
R144B_HUMAN | [view interactions] | Low throughput | no | yes |
CRTC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TIF1A_HUMAN | [view interactions] | Low throughput | no | yes |
PTN6_HUMAN | [view interactions] | Low throughput | no | no |
BLK_HUMAN | [view interactions] | Low throughput | no | no |
MFN1_HUMAN | [view interactions] | Low throughput | no | yes |
FOXO1_HUMAN | [view interactions] | Low throughput | no | yes |
NED4L_HUMAN | [view interactions] | Low throughput | no | yes |
AT1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MFF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SMUF1_HUMAN | [view interactions] | Low throughput | no | yes |
TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
TNR6_HUMAN | [view interactions] | Low throughput | no | no |
CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
CELF2_HUMAN | [view interactions] | Low throughput | no | yes |
HNRPC_HUMAN | [view interactions] | Low throughput | no | yes |
PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TRADD_HUMAN | [view interactions] | Low throughput | no | yes |
RIPK1_HUMAN | [view interactions] | Low throughput | no | yes |
TNR4_HUMAN | [view interactions] | Low throughput | no | no |
TNR9_HUMAN | [view interactions] | Low throughput | no | no |
TNR5_HUMAN | [view interactions] | Low throughput | no | no |
TNR11_HUMAN | [view interactions] | Low throughput | no | yes |
MIPT3_HUMAN | [view interactions] | Low throughput | no | yes |
RIPK2_HUMAN | [view interactions] | Low throughput | no | yes |
GMEB1_HUMAN | [view interactions] | Low throughput | no | yes |
EDAR_HUMAN | [view interactions] | Low throughput | no | yes |
ZMY11_HUMAN | [view interactions] | Low throughput | no | no |
TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TNR3_HUMAN | [view interactions] | Low throughput | no | yes |
PPBT_HUMAN | [view interactions] | Low throughput | no | yes |
TANK_HUMAN | [view interactions] | Low throughput | no | yes |
TLR4_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF5_HUMAN | [view interactions] | Low throughput | no | yes |
BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
BIRC3_HUMAN | [view interactions] | Low throughput | no | no |
PTN22_HUMAN | [view interactions] | Low throughput | no | yes |
M3K14_HUMAN | [view interactions] | Low throughput | no | yes |
TNR8_HUMAN | [view interactions] | Low throughput | no | no |
TNR27_HUMAN | [view interactions] | Low throughput | no | no |
E2AK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRAK1_HUMAN | [view interactions] | Low throughput | no | yes |
MYD88_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WDR5_HUMAN | [view interactions] | Low throughput | no | no |
TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IKKE_HUMAN | [view interactions] | Low throughput | no | yes |
TNR14_HUMAN | [view interactions] | Low throughput | no | no |
MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RL40_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BRAF_HUMAN | [view interactions] | Low throughput | no | yes |
TCAM1_HUMAN | [view interactions] | Low throughput | no | yes |
IL1AP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DDX58_HUMAN | [view interactions] | Low throughput | no | yes |
OTU7B_HUMAN | [view interactions] | Low throughput | no | yes |
MALT1_HUMAN | [view interactions] | Low throughput | no | no |
T3JAM_HUMAN | [view interactions] | Low throughput | no | no |
TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NUP62_HUMAN | [view interactions] | Low throughput | no | yes |
TNR18_HUMAN | [view interactions] | Low throughput | no | no |
TNR12_HUMAN | [view interactions] | Low throughput | no | yes |
UBC9_HUMAN | [view interactions] | Low throughput | no | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
TNF14_HUMAN | [view interactions] | Low throughput | no | yes |
TYDP2_HUMAN | [view interactions] | Low throughput | no | no |
CD27_HUMAN | [view interactions] | Low throughput | no | no |
CFLAR_HUMAN | [view interactions] | Low throughput | no | yes |
TNR17_HUMAN | [view interactions] | Low throughput | no | no |
CIKS_HUMAN | [view interactions] | Low throughput | no | yes |
TNR19_HUMAN | [view interactions] | Low throughput | no | no |
OTUD5_HUMAN | [view interactions] | Low throughput | no | yes |
ZBP1_HUMAN | [view interactions] | High throughput | no | yes |
TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
TRAF1_HUMAN | [view interactions] | High throughput | no | no |
UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
GALC_HUMAN | [view interactions] | High throughput | no | yes |
DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
TROAP_HUMAN | [view interactions] | High throughput | no | yes |
MYT1_HUMAN | [view interactions] | High throughput | no | yes |
KSYK_HUMAN | [view interactions] | High throughput | no | no |
NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
FA53C_HUMAN | [view interactions] | High throughput | no | yes |
IFIT3_HUMAN | [view interactions] | High throughput | no | yes |
TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
VAV3_HUMAN | [view interactions] | High throughput | no | yes |
TNFA_HUMAN | [view interactions] | High throughput | no | no |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
CASP2_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
EYA3_HUMAN | [view interactions] | High throughput | no | no |
LG3BP_HUMAN | [view interactions] | High throughput | no | no |
UBP7_HUMAN | [view interactions] | High throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DX39A_HUMAN | [view interactions] | High throughput | no | yes |
NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCKP5_HUMAN | [view interactions] | High throughput | no | no |
DAZL_HUMAN | [view interactions] | High throughput | no | no |
KRT38_HUMAN | [view interactions] | High throughput | no | no |
PCD10_HUMAN | [view interactions] | High throughput | no | yes |
HECD3_HUMAN | [view interactions] | High throughput | no | yes |
GSTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCRU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PISD_HUMAN | [view interactions] | High throughput | no | yes |
S2540_HUMAN | [view interactions] | High throughput | no | no |
HDHD3_HUMAN | [view interactions] | High throughput | no | yes |
G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDS2_HUMAN | [view interactions] | High throughput | no | yes |
ACBP_HUMAN | [view interactions] | High throughput | no | yes |
THIC_HUMAN | [view interactions] | High throughput | no | yes |
RETST_HUMAN | [view interactions] | High throughput | no | yes |
PDE9A_HUMAN | [view interactions] | High throughput | no | yes |
S4A7_HUMAN | [view interactions] | High throughput | no | no |
KGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AL3A1_HUMAN | [view interactions] | High throughput | no | no |
MAOX_HUMAN | [view interactions] | High throughput | no | yes |
CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGM2_HUMAN | [view interactions] | High throughput | no | no |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
GSTO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACPH_HUMAN | [view interactions] | High throughput | no | yes |
SERC_HUMAN | [view interactions] | High throughput | no | yes |
UGPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GCYB1_HUMAN | [view interactions] | High throughput | no | yes |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PXDC2_HUMAN | [view interactions] | High throughput | no | yes |
SEC63_HUMAN | [view interactions] | High throughput | no | yes |
IL1B_HUMAN | [view interactions] | High throughput | no | no |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
DAXX_HUMAN | [view interactions] | High throughput | no | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
MRP1_HUMAN | [view interactions] | High throughput | no | no |
ABC3C_HUMAN | [view interactions] | High throughput | no | no |
IRF1_HUMAN | [view interactions] | High throughput | no | yes |
AZI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TLR3_HUMAN | [view interactions] | High throughput | no | yes |
TLR9_HUMAN | [view interactions] | High throughput | no | no |
USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSKS_HUMAN | [view interactions] | High throughput | no | no |
SNP29_HUMAN | [view interactions] | High throughput | no | yes |
ECH1_HUMAN | [view interactions] | High throughput | no | yes |
SHPK_HUMAN | [view interactions] | High throughput | no | no |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ETV6_HUMAN | [view interactions] | High throughput | no | no |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IL15_HUMAN | [view interactions] | High throughput | no | yes |
SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIVM_HUMAN | [view interactions] | High throughput | no | yes |
RIPP1_HUMAN | [view interactions] | High throughput | no | no |
GMEB2_HUMAN | [view interactions] | High throughput | no | yes |
IFT25_HUMAN | [view interactions] | High throughput | no | yes |
CJ062_HUMAN | [view interactions] | High throughput | no | no |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
CC184_HUMAN | [view interactions] | High throughput | no | no |
ZBT49_HUMAN | [view interactions] | High throughput | no | yes |
IP6K3_HUMAN | [view interactions] | High throughput | no | no |
LNX1_HUMAN | [view interactions] | High throughput | no | yes |
RD23A_HUMAN | [view interactions] | High throughput | no | yes |
ZSCA4_HUMAN | [view interactions] | High throughput | no | no |
CCD13_HUMAN | [view interactions] | High throughput | no | no |
RNF4_HUMAN | [view interactions] | High throughput | no | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDZD4_HUMAN | [view interactions] | High throughput | no | yes |
PIAS2_HUMAN | [view interactions] | High throughput | no | yes |
HEMGN_HUMAN | [view interactions] | High throughput | no | no |
ASCC1_HUMAN | [view interactions] | High throughput | no | yes |
P121A_HUMAN | [view interactions] | High throughput | no | yes |
PSB8_HUMAN | [view interactions] | High throughput | no | yes |
M3K1_HUMAN | [view interactions] | Computational | no | yes |
IKKB_HUMAN | [view interactions] | Computational | no | yes |
TCAM2_HUMAN | [view interactions] | Computational | no | no |
BTK_HUMAN | [view interactions] | Computational | no | no |
IRF7_HUMAN | [view interactions] | Computational | no | yes |
M4K4_HUMAN | [view interactions] | Computational | no | yes |
IKKA_HUMAN | [view interactions] | Computational | no | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TN13B_HUMAN | [view interactions] | Computational | no | no |
PTN11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TNF13_HUMAN | [view interactions] | Computational | no | yes |
RAP1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MP2K7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TRI25_HUMAN | [view interactions] | Computational | no | yes |
TAB3_HUMAN | [view interactions] | Computational | no | yes |
MYOM2_HUMAN | [view interactions] | Computational | no | yes |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CD40L_HUMAN | [view interactions] | Computational | no | no |
SARM1_HUMAN | [view interactions] | Computational | no | yes |
TAB1_HUMAN | [view interactions] | Computational | no | yes |
TAB2_HUMAN | [view interactions] | Computational | no | yes |
NAL12_HUMAN | [view interactions] | Computational | no | yes |
MK08_HUMAN | [view interactions] | Computational | no | yes |
MK09_HUMAN | [view interactions] | Computational | no | yes |
UBE2N_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TNFB_HUMAN | [view interactions] | Computational | no | no |