Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TRAF3_HUMAN

Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote Lys-63-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.
Position Amino acid Mutation Disease Overlap with binding region
118 Arg Trp Encephalopathy,acute,infection-induced,5,herpes-specific(IIAE5) -
ELM instance Name Type Start End Partner
ELMI003711 LIG_SH2_STAP1 LIG 482 486 -
ELMI003831 MOD_CK1_1 MOD 349 355 -

Molecular function

Term Name % Distance from the top of the tree Annotated in TRAF3_HUMAN
GO:0046872 metal ion binding 31.4815 4 yes
GO:0017076 purine nucleotide binding 29.6296 4 no
GO:0032555 purine ribonucleotide binding 29.6296 4 no
GO:0035639 purine ribonucleoside triphosphate binding 29.6296 4 no
GO:0019900 kinase binding 27.7778 4 yes
GO:0031625 ubiquitin protein ligase binding 27.7778 5 yes
GO:0044389 ubiquitin-like protein ligase binding 27.7778 4 yes
GO:0019901 protein kinase binding 25.9259 5 yes
GO:0005524 ATP binding 22.2222 5 no
GO:0030554 adenyl nucleotide binding 22.2222 5 no
GO:0032559 adenyl ribonucleotide binding 22.2222 5 no
GO:0004842 ubiquitin-protein transferase activity 18.5185 4 yes
GO:0019902 phosphatase binding 12.9630 4 yes
GO:0019903 protein phosphatase binding 11.1111 5 yes
GO:0005126 cytokine receptor binding 9.2593 4 yes
GO:0008270 zinc ion binding 9.2593 6 yes
GO:0046914 transition metal ion binding 9.2593 5 yes
GO:0032813 tumor necrosis factor receptor superfamily binding 7.4074 5 yes
GO:0005164 tumor necrosis factor receptor binding 5.5556 6 yes
GO:0031996 thioesterase binding 5.5556 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in TRAF3_HUMAN
GO:0048522 positive regulation of cellular process 72.2222 4 yes
GO:0060255 regulation of macromolecule metabolic process 70.3704 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 62.9630 4 yes
GO:0080090 regulation of primary metabolic process 62.9630 4 yes
GO:0010646 regulation of cell communication 59.2593 4 yes
GO:0031323 regulation of cellular metabolic process 57.4074 4 yes
GO:0009966 regulation of signal transduction 53.7037 4 yes
GO:0010468 regulation of gene expression 51.8519 5 yes
GO:0009893 positive regulation of metabolic process 51.8519 4 no
GO:0036211 protein modification process 50.0000 4 yes
GO:0043412 macromolecule modification 50.0000 4 yes
GO:0051246 regulation of protein metabolic process 50.0000 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0048523 negative regulation of cellular process 48.1481 4 no
GO:0051128 regulation of cellular component organization 44.4444 4 no
GO:0010647 positive regulation of cell communication 44.4444 5 yes
GO:0023056 positive regulation of signaling 44.4444 4 yes
GO:0048584 positive regulation of response to stimulus 44.4444 4 yes
GO:0009967 positive regulation of signal transduction 42.5926 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 40.7407 5 no
GO:1902531 regulation of intracellular signal transduction 38.8889 5 yes
GO:0031325 positive regulation of cellular metabolic process 38.8889 5 no
GO:0051049 regulation of transport 37.0370 4 no
GO:0009889 regulation of biosynthetic process 37.0370 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 37.0370 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 37.0370 5 yes
GO:0006355 regulation of DNA-templated transcription 35.1852 6 yes
GO:0031326 regulation of cellular biosynthetic process 35.1852 5 yes
GO:0051252 regulation of RNA metabolic process 35.1852 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 35.1852 7 yes
GO:2001141 regulation of RNA biosynthetic process 35.1852 6 yes
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:1902533 positive regulation of intracellular signal transduction 33.3333 6 yes
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0051130 positive regulation of cellular component organization 31.4815 5 no
GO:0031399 regulation of protein modification process 31.4815 6 no
GO:0080134 regulation of response to stress 31.4815 4 yes
GO:0060341 regulation of cellular localization 29.6296 4 no
GO:0010941 regulation of cell death 29.6296 4 yes
GO:0006796 phosphate-containing compound metabolic process 29.6296 4 no
GO:0008104 protein localization 29.6296 4 no
GO:0010648 negative regulation of cell communication 29.6296 5 no
GO:0023057 negative regulation of signaling 29.6296 4 no
GO:0051050 positive regulation of transport 27.7778 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 27.7778 5 no
GO:0051240 positive regulation of multicellular organismal process 27.7778 4 no
GO:0051094 positive regulation of developmental process 27.7778 4 no
GO:0019220 regulation of phosphate metabolic process 27.7778 6 no
GO:0042325 regulation of phosphorylation 27.7778 7 no
GO:0051174 regulation of phosphorus metabolic process 27.7778 5 no
GO:0042981 regulation of apoptotic process 27.7778 6 yes
GO:0043067 regulation of programmed cell death 27.7778 5 yes
GO:0043408 regulation of MAPK cascade 27.7778 6 yes
GO:0070647 protein modification by small protein conjugation or removal 27.7778 5 yes
GO:0032880 regulation of protein localization 25.9259 5 no
GO:0006996 organelle organization 25.9259 4 no
GO:0044087 regulation of cellular component biogenesis 25.9259 4 no
GO:0031401 positive regulation of protein modification process 25.9259 7 no
GO:0001932 regulation of protein phosphorylation 25.9259 7 no
GO:0051338 regulation of transferase activity 25.9259 4 no
GO:0016567 protein ubiquitination 25.9259 7 yes
GO:0030162 regulation of proteolysis 25.9259 6 yes
GO:0032446 protein modification by small protein conjugation 25.9259 6 yes
GO:0031324 negative regulation of cellular metabolic process 25.9259 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 24.0741 6 no
GO:0048585 negative regulation of response to stimulus 24.0741 4 no
GO:0016192 vesicle-mediated transport 24.0741 4 no
GO:0001817 regulation of cytokine production 24.0741 4 yes
GO:0010628 positive regulation of gene expression 24.0741 6 no
GO:0045595 regulation of cell differentiation 22.2222 4 no
GO:0071310 cellular response to organic substance 22.2222 4 no
GO:0006508 proteolysis 22.2222 4 no
GO:0009057 macromolecule catabolic process 22.2222 4 no
GO:0019941 modification-dependent protein catabolic process 22.2222 6 no
GO:0043632 modification-dependent macromolecule catabolic process 22.2222 5 no
GO:0044265 cellular macromolecule catabolic process 22.2222 4 no
GO:0051603 proteolysis involved in protein catabolic process 22.2222 5 no
GO:0033043 regulation of organelle organization 22.2222 5 no
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0043085 positive regulation of catalytic activity 22.2222 4 no
GO:0043549 regulation of kinase activity 22.2222 5 no
GO:0031328 positive regulation of cellular biosynthetic process 20.3704 6 no
GO:0031344 regulation of cell projection organization 20.3704 5 no
GO:0050804 modulation of chemical synaptic transmission 20.3704 5 no
GO:0099177 regulation of trans-synaptic signaling 20.3704 4 no
GO:0051248 negative regulation of protein metabolic process 20.3704 6 no
GO:0022607 cellular component assembly 20.3704 4 no
GO:0010562 positive regulation of phosphorus metabolic process 20.3704 6 no
GO:0042327 positive regulation of phosphorylation 20.3704 8 no
GO:0045937 positive regulation of phosphate metabolic process 20.3704 7 no
GO:0043410 positive regulation of MAPK cascade 20.3704 7 yes
GO:0050776 regulation of immune response 20.3704 4 yes
GO:0009891 positive regulation of biosynthetic process 20.3704 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.3704 6 no
GO:0022603 regulation of anatomical structure morphogenesis 20.3704 4 no
GO:0031347 regulation of defense response 18.5185 5 yes
GO:0032101 regulation of response to external stimulus 18.5185 4 yes
GO:0080135 regulation of cellular response to stress 18.5185 4 yes
GO:0032872 regulation of stress-activated MAPK cascade 16.6667 6 yes
GO:0070302 regulation of stress-activated protein kinase signaling cascade 16.6667 5 yes
GO:0000209 protein polyubiquitination 14.8148 8 yes
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 14.8148 6 yes
GO:0046328 regulation of JNK cascade 14.8148 7 yes
GO:0002831 regulation of response to biotic stimulus 12.9630 4 yes
GO:0006915 apoptotic process 12.9630 4 yes
GO:0032479 regulation of type I interferon production 12.9630 5 yes
GO:0032874 positive regulation of stress-activated MAPK cascade 12.9630 7 yes
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 12.9630 6 yes
GO:0032648 regulation of interferon-beta production 11.1111 6 yes
GO:0046330 positive regulation of JNK cascade 11.1111 8 yes
GO:0070534 protein K63-linked ubiquitination 11.1111 9 yes
GO:0019221 cytokine-mediated signaling pathway 9.2593 4 yes
GO:0032088 negative regulation of NF-kappaB transcription factor activity 7.4074 5 yes
GO:0043433 negative regulation of DNA-binding transcription factor activity 7.4074 4 yes
GO:0002221 pattern recognition receptor signaling pathway 5.5556 4 yes
GO:0002224 toll-like receptor signaling pathway 5.5556 5 yes
GO:0008063 Toll signaling pathway 5.5556 4 yes
GO:0050688 regulation of defense response to virus 5.5556 5 yes
GO:0002756 MyD88-independent toll-like receptor signaling pathway 3.7037 6 yes
GO:0033209 tumor necrosis factor-mediated signaling pathway 3.7037 5 yes
GO:0035666 TRIF-dependent toll-like receptor signaling pathway 3.7037 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in TRAF3_HUMAN
DOID:331 central nervous system disease 5.5556 3 no
DOID:1289 neurodegenerative disease 3.7037 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TRAIP_HUMAN [view interactions] Low throughput no yes
OTUB1_HUMAN [view interactions] Low throughput no yes
OTUB2_HUMAN [view interactions] Low throughput no no
RN216_HUMAN [view entry] [view interactions] Low throughput yes yes
NLRX1_HUMAN [view interactions] Low throughput no yes
RNF41_HUMAN [view interactions] Low throughput no yes
OPTN_HUMAN [view interactions] Low throughput no yes
CBLB_HUMAN [view interactions] Low throughput no yes
TNR1B_HUMAN [view interactions] Low throughput no no
TR13C_HUMAN [view interactions] Low throughput no no
TR13B_HUMAN [view interactions] Low throughput no yes
IRF3_HUMAN [view interactions] Low throughput no yes
NF2IP_HUMAN [view interactions] Low throughput no no
PP2BA_HUMAN [view entry] [view interactions] Low throughput yes yes
CANB1_HUMAN [view entry] [view interactions] Low throughput yes yes
TFG_HUMAN [view interactions] Low throughput no yes
UCHL1_HUMAN [view entry] [view interactions] Low throughput yes yes
NEMO_HUMAN [view interactions] Low throughput no yes
PP1G_HUMAN [view entry] [view interactions] Low throughput yes yes
STING_HUMAN [view interactions] Low throughput no yes
RN166_HUMAN [view interactions] Low throughput no no
ESR1_HUMAN [view interactions] Low throughput no no
CREB1_HUMAN [view interactions] Low throughput no yes
MYSM1_HUMAN [view interactions] Low throughput no yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
ASC_HUMAN [view interactions] Low throughput no no
M3K7_HUMAN [view interactions] Low throughput no yes
TRI14_HUMAN [view interactions] Low throughput no yes
KC1E_HUMAN [view entry] [view interactions] Low throughput yes yes
FOSL1_HUMAN [view interactions] Low throughput no yes
DDX3X_HUMAN [view entry] [view interactions] Low throughput yes yes
OSTP_HUMAN [view interactions] Low throughput no yes
STK38_HUMAN [view entry] [view interactions] Low throughput yes yes
I17RA_HUMAN [view interactions] Low throughput no yes
KAPCB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP1_HUMAN [view interactions] Low throughput no yes
WDR82_HUMAN [view interactions] Low throughput no no
ZC12A_HUMAN [view interactions] Low throughput no yes
U17L2_HUMAN [view interactions] Low throughput no no
DHX58_HUMAN [view interactions] Low throughput no yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP25_HUMAN [view interactions] Low throughput no yes
ABCF1_HUMAN [view interactions] Low throughput no yes
PINK1_HUMAN [view interactions] Low throughput no yes
MSRE_HUMAN [view interactions] Low throughput no no
R144B_HUMAN [view interactions] Low throughput no yes
CRTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
TIF1A_HUMAN [view interactions] Low throughput no yes
PTN6_HUMAN [view interactions] Low throughput no no
BLK_HUMAN [view interactions] Low throughput no no
MFN1_HUMAN [view interactions] Low throughput no yes
FOXO1_HUMAN [view interactions] Low throughput no yes
NED4L_HUMAN [view interactions] Low throughput no yes
AT1B1_HUMAN [view entry] [view interactions] Low throughput yes no
MFF_HUMAN [view entry] [view interactions] Low throughput yes yes
SMUF1_HUMAN [view interactions] Low throughput no yes
TNR1A_HUMAN [view interactions] Low throughput no yes
TNR6_HUMAN [view interactions] Low throughput no no
CASP3_HUMAN [view interactions] Low throughput no yes
CELF2_HUMAN [view interactions] Low throughput no yes
HNRPC_HUMAN [view interactions] Low throughput no yes
PDLI7_HUMAN [view entry] [view interactions] Low throughput yes no
TRADD_HUMAN [view interactions] Low throughput no yes
RIPK1_HUMAN [view interactions] Low throughput no yes
TNR4_HUMAN [view interactions] Low throughput no no
TNR9_HUMAN [view interactions] Low throughput no no
TNR5_HUMAN [view interactions] Low throughput no no
TNR11_HUMAN [view interactions] Low throughput no yes
MIPT3_HUMAN [view interactions] Low throughput no yes
RIPK2_HUMAN [view interactions] Low throughput no yes
GMEB1_HUMAN [view interactions] Low throughput no yes
EDAR_HUMAN [view interactions] Low throughput no yes
ZMY11_HUMAN [view interactions] Low throughput no no
TNR16_HUMAN [view entry] [view interactions] Low throughput yes no
TNR3_HUMAN [view interactions] Low throughput no yes
PPBT_HUMAN [view interactions] Low throughput no yes
TANK_HUMAN [view interactions] Low throughput no yes
TLR4_HUMAN [view interactions] Low throughput no yes
TRAF2_HUMAN [view interactions] Low throughput no yes
TRAF5_HUMAN [view interactions] Low throughput no yes
BIRC2_HUMAN [view interactions] Low throughput no yes
BIRC3_HUMAN [view interactions] Low throughput no no
PTN22_HUMAN [view interactions] Low throughput no yes
M3K14_HUMAN [view interactions] Low throughput no yes
TNR8_HUMAN [view interactions] Low throughput no no
TNR27_HUMAN [view interactions] Low throughput no no
E2AK2_HUMAN [view entry] [view interactions] Low throughput yes yes
IRAK1_HUMAN [view interactions] Low throughput no yes
MYD88_HUMAN [view entry] [view interactions] Low throughput yes yes
WDR5_HUMAN [view interactions] Low throughput no no
TBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKE_HUMAN [view interactions] Low throughput no yes
TNR14_HUMAN [view interactions] Low throughput no no
MAVS_HUMAN [view interactions] Low throughput no yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
BRAF_HUMAN [view interactions] Low throughput no yes
TCAM1_HUMAN [view interactions] Low throughput no yes
IL1AP_HUMAN [view entry] [view interactions] Low throughput yes yes
DDX58_HUMAN [view interactions] Low throughput no yes
OTU7B_HUMAN [view interactions] Low throughput no yes
MALT1_HUMAN [view interactions] Low throughput no no
T3JAM_HUMAN [view interactions] Low throughput no no
TRAF3_HUMAN [view entry] [view interactions] Low throughput yes yes
NUP62_HUMAN [view interactions] Low throughput no yes
TNR18_HUMAN [view interactions] Low throughput no no
TNR12_HUMAN [view interactions] Low throughput no yes
UBC9_HUMAN [view interactions] Low throughput no yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
M3K5_HUMAN [view interactions] Low throughput no yes
TNF14_HUMAN [view interactions] Low throughput no yes
TYDP2_HUMAN [view interactions] Low throughput no no
CD27_HUMAN [view interactions] Low throughput no no
CFLAR_HUMAN [view interactions] Low throughput no yes
TNR17_HUMAN [view interactions] Low throughput no no
CIKS_HUMAN [view interactions] Low throughput no yes
TNR19_HUMAN [view interactions] Low throughput no no
OTUD5_HUMAN [view interactions] Low throughput no yes
ZBP1_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
TAXB1_HUMAN [view interactions] High throughput no yes
TRAF1_HUMAN [view interactions] High throughput no no
UBE2O_HUMAN [view interactions] High throughput no yes
SC16A_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
DCAF7_HUMAN [view interactions] High throughput no yes
GALC_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
TROAP_HUMAN [view interactions] High throughput no yes
MYT1_HUMAN [view interactions] High throughput no yes
KSYK_HUMAN [view interactions] High throughput no no
NMRL1_HUMAN [view interactions] High throughput no yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
ASPP1_HUMAN [view interactions] High throughput no yes
FA53C_HUMAN [view interactions] High throughput no yes
IFIT3_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
VAV3_HUMAN [view interactions] High throughput no yes
TNFA_HUMAN [view interactions] High throughput no no
CACO2_HUMAN [view interactions] High throughput no yes
CASP2_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
EYA3_HUMAN [view interactions] High throughput no no
LG3BP_HUMAN [view interactions] High throughput no no
UBP7_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
DX39A_HUMAN [view interactions] High throughput no yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
NCKP5_HUMAN [view interactions] High throughput no no
DAZL_HUMAN [view interactions] High throughput no no
KRT38_HUMAN [view interactions] High throughput no no
PCD10_HUMAN [view interactions] High throughput no yes
HECD3_HUMAN [view interactions] High throughput no yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
KCRU_HUMAN [view entry] [view interactions] High throughput yes yes
PISD_HUMAN [view interactions] High throughput no yes
S2540_HUMAN [view interactions] High throughput no no
HDHD3_HUMAN [view interactions] High throughput no yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
CDS2_HUMAN [view interactions] High throughput no yes
ACBP_HUMAN [view interactions] High throughput no yes
THIC_HUMAN [view interactions] High throughput no yes
RETST_HUMAN [view interactions] High throughput no yes
PDE9A_HUMAN [view interactions] High throughput no yes
S4A7_HUMAN [view interactions] High throughput no no
KGP2_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
AL3A1_HUMAN [view interactions] High throughput no no
MAOX_HUMAN [view interactions] High throughput no yes
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
CAP1_HUMAN [view entry] [view interactions] High throughput yes yes
PGM2_HUMAN [view interactions] High throughput no no
P85B_HUMAN [view interactions] High throughput no yes
GSTO1_HUMAN [view entry] [view interactions] High throughput yes yes
ACPH_HUMAN [view interactions] High throughput no yes
SERC_HUMAN [view interactions] High throughput no yes
UGPA_HUMAN [view entry] [view interactions] High throughput yes no
GCYB1_HUMAN [view interactions] High throughput no yes
ANM1_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
PXDC2_HUMAN [view interactions] High throughput no yes
SEC63_HUMAN [view interactions] High throughput no yes
IL1B_HUMAN [view interactions] High throughput no no
MLP3B_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
DAXX_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
MRP1_HUMAN [view interactions] High throughput no no
ABC3C_HUMAN [view interactions] High throughput no no
IRF1_HUMAN [view interactions] High throughput no yes
AZI2_HUMAN [view entry] [view interactions] High throughput yes yes
TLR3_HUMAN [view interactions] High throughput no yes
TLR9_HUMAN [view interactions] High throughput no no
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
TSKS_HUMAN [view interactions] High throughput no no
SNP29_HUMAN [view interactions] High throughput no yes
ECH1_HUMAN [view interactions] High throughput no yes
SHPK_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
ETV6_HUMAN [view interactions] High throughput no no
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
IL15_HUMAN [view interactions] High throughput no yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
BIVM_HUMAN [view interactions] High throughput no yes
RIPP1_HUMAN [view interactions] High throughput no no
GMEB2_HUMAN [view interactions] High throughput no yes
IFT25_HUMAN [view interactions] High throughput no yes
CJ062_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
NTAQ1_HUMAN [view interactions] High throughput no yes
CC184_HUMAN [view interactions] High throughput no no
ZBT49_HUMAN [view interactions] High throughput no yes
IP6K3_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
RD23A_HUMAN [view interactions] High throughput no yes
ZSCA4_HUMAN [view interactions] High throughput no no
CCD13_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
SHRPN_HUMAN [view entry] [view interactions] High throughput yes yes
PDZD4_HUMAN [view interactions] High throughput no yes
PIAS2_HUMAN [view interactions] High throughput no yes
HEMGN_HUMAN [view interactions] High throughput no no
ASCC1_HUMAN [view interactions] High throughput no yes
P121A_HUMAN [view interactions] High throughput no yes
PSB8_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] Computational no yes
IKKB_HUMAN [view interactions] Computational no yes
TCAM2_HUMAN [view interactions] Computational no no
BTK_HUMAN [view interactions] Computational no no
IRF7_HUMAN [view interactions] Computational no yes
M4K4_HUMAN [view interactions] Computational no yes
IKKA_HUMAN [view interactions] Computational no yes
ARRB2_HUMAN [view entry] [view interactions] Computational yes no
TN13B_HUMAN [view interactions] Computational no no
PTN11_HUMAN [view entry] [view interactions] Computational yes yes
TNF13_HUMAN [view interactions] Computational no yes
RAP1A_HUMAN [view entry] [view interactions] Computational yes no
MP2K7_HUMAN [view entry] [view interactions] Computational yes yes
TRI25_HUMAN [view interactions] Computational no yes
TAB3_HUMAN [view interactions] Computational no yes
MYOM2_HUMAN [view interactions] Computational no yes
RASH_HUMAN [view entry] [view interactions] Computational yes no
CD40L_HUMAN [view interactions] Computational no no
SARM1_HUMAN [view interactions] Computational no yes
TAB1_HUMAN [view interactions] Computational no yes
TAB2_HUMAN [view interactions] Computational no yes
NAL12_HUMAN [view interactions] Computational no yes
MK08_HUMAN [view interactions] Computational no yes
MK09_HUMAN [view interactions] Computational no yes
UBE2N_HUMAN [view entry] [view interactions] Computational yes yes
TNFB_HUMAN [view interactions] Computational no no