SHRPN_HUMAN
Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SHRPN_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 19.2308 | 4 | yes |
GO:0004842 | ubiquitin-protein transferase activity | 9.6154 | 4 | yes |
GO:0031593 | polyubiquitin modification-dependent protein binding | 5.7692 | 4 | yes |
GO:0043130 | ubiquitin binding | 5.7692 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SHRPN_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 63.4615 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 48.0769 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 48.0769 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 48.0769 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 44.2308 | 4 | no |
GO:0048523 | negative regulation of cellular process | 44.2308 | 4 | no |
GO:0010646 | regulation of cell communication | 42.3077 | 4 | yes |
GO:0009966 | regulation of signal transduction | 40.3846 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 40.3846 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 38.4615 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 36.5385 | 4 | no |
GO:0010647 | positive regulation of cell communication | 34.6154 | 5 | yes |
GO:0023056 | positive regulation of signaling | 34.6154 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 34.6154 | 5 | no |
GO:0010468 | regulation of gene expression | 32.6923 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 32.6923 | 5 | no |
GO:0051094 | positive regulation of developmental process | 32.6923 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 32.6923 | 5 | no |
GO:0006996 | organelle organization | 30.7692 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 30.7692 | 5 | yes |
GO:0036211 | protein modification process | 30.7692 | 4 | yes |
GO:0043412 | macromolecule modification | 30.7692 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 30.7692 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 30.7692 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 30.7692 | 5 | no |
GO:0010941 | regulation of cell death | 28.8462 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.8462 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 28.8462 | 5 | no |
GO:0042981 | regulation of apoptotic process | 28.8462 | 6 | no |
GO:0043067 | regulation of programmed cell death | 28.8462 | 5 | no |
GO:0022607 | cellular component assembly | 28.8462 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 26.9231 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 26.9231 | 5 | no |
GO:0009894 | regulation of catabolic process | 26.9231 | 4 | no |
GO:0031344 | regulation of cell projection organization | 26.9231 | 5 | no |
GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
GO:0031399 | regulation of protein modification process | 25.0000 | 6 | no |
GO:0044087 | regulation of cellular component biogenesis | 25.0000 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 25.0000 | 6 | no |
GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 25.0000 | 4 | no |
GO:0006508 | proteolysis | 23.0769 | 4 | yes |
GO:0009057 | macromolecule catabolic process | 23.0769 | 4 | yes |
GO:0080134 | regulation of response to stress | 23.0769 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 23.0769 | 6 | no |
GO:0010648 | negative regulation of cell communication | 23.0769 | 5 | no |
GO:0023057 | negative regulation of signaling | 23.0769 | 4 | no |
GO:0045595 | regulation of cell differentiation | 23.0769 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.0769 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 23.0769 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 23.0769 | 6 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.0769 | 6 | no |
GO:0008104 | protein localization | 23.0769 | 4 | no |
GO:0051049 | regulation of transport | 23.0769 | 4 | no |
GO:0019941 | modification-dependent protein catabolic process | 21.1538 | 6 | yes |
GO:0043632 | modification-dependent macromolecule catabolic process | 21.1538 | 5 | yes |
GO:0044265 | cellular macromolecule catabolic process | 21.1538 | 4 | yes |
GO:0051603 | proteolysis involved in protein catabolic process | 21.1538 | 5 | yes |
GO:0009968 | negative regulation of signal transduction | 21.1538 | 5 | no |
GO:0031324 | negative regulation of cellular metabolic process | 21.1538 | 5 | no |
GO:0043066 | negative regulation of apoptotic process | 21.1538 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 21.1538 | 6 | no |
GO:0060548 | negative regulation of cell death | 21.1538 | 5 | no |
GO:0031329 | regulation of cellular catabolic process | 21.1538 | 5 | no |
GO:0006511 | ubiquitin-dependent protein catabolic process | 19.2308 | 7 | yes |
GO:0030163 | protein catabolic process | 17.3077 | 4 | yes |
GO:0070647 | protein modification by small protein conjugation or removal | 17.3077 | 5 | yes |
GO:1901565 | organonitrogen compound catabolic process | 17.3077 | 4 | yes |
GO:0010498 | proteasomal protein catabolic process | 15.3846 | 5 | yes |
GO:0016567 | protein ubiquitination | 13.4615 | 7 | yes |
GO:0032446 | protein modification by small protein conjugation | 13.4615 | 6 | yes |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 13.4615 | 6 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 13.4615 | 6 | yes |
GO:0022411 | cellular component disassembly | 11.5385 | 4 | yes |
GO:0000209 | protein polyubiquitination | 9.6154 | 8 | yes |
GO:0007420 | brain development | 9.6154 | 4 | yes |
GO:0032101 | regulation of response to external stimulus | 9.6154 | 4 | yes |
GO:0007005 | mitochondrion organization | 7.6923 | 5 | yes |
GO:0031347 | regulation of defense response | 7.6923 | 5 | yes |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 7.6923 | 6 | yes |
GO:0001959 | regulation of cytokine-mediated signaling pathway | 5.7692 | 5 | yes |
GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway | 5.7692 | 6 | yes |
GO:0032102 | negative regulation of response to external stimulus | 5.7692 | 5 | yes |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 5.7692 | 7 | yes |
GO:0050727 | regulation of inflammatory response | 5.7692 | 5 | yes |
GO:0060759 | regulation of response to cytokine stimulus | 5.7692 | 4 | yes |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 3.8462 | 5 | yes |
GO:0030262 | apoptotic nuclear changes | 3.8462 | 6 | yes |
GO:0031348 | negative regulation of defense response | 3.8462 | 5 | yes |
GO:0042742 | defense response to bacterium | 3.8462 | 4 | yes |
GO:0050728 | negative regulation of inflammatory response | 3.8462 | 6 | yes |
GO:0097039 | protein linear polyubiquitination | 3.8462 | 9 | yes |
GO:2000348 | regulation of CD40 signaling pathway | 3.8462 | 5 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in SHRPN_HUMAN |
---|---|---|---|---|
DOID:0050686 | organ system cancer | 3.8462 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
OTUL_HUMAN | [view interactions] | Low throughput | no | yes |
TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
ITAL_HUMAN | [view interactions] | Low throughput | no | no |
TRAF1_HUMAN | [view interactions] | Low throughput | no | no |
PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
ANM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SKI_HUMAN | [view interactions] | Low throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP20_HUMAN | [view interactions] | Low throughput | no | yes |
ITA2B_HUMAN | [view interactions] | Low throughput | no | no |
CASP1_HUMAN | [view interactions] | Low throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
PPIL3_HUMAN | [view interactions] | Low throughput | no | yes |
ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITAM_HUMAN | [view interactions] | Low throughput | no | no |
ITAD_HUMAN | [view interactions] | Low throughput | no | no |
HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHAN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EYA1_HUMAN | [view interactions] | Low throughput | no | no |
EYA2_HUMAN | [view interactions] | Low throughput | no | yes |
RNF31_HUMAN | [view interactions] | Low throughput | no | yes |
SHRPN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TNFA_HUMAN | [view interactions] | Low throughput | no | no |
TNAP3_HUMAN | [view interactions] | Low throughput | no | yes |
HOIL1_HUMAN | [view interactions] | Low throughput | no | no |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
NOD2_HUMAN | [view interactions] | Low throughput | no | yes |
ITA1_HUMAN | [view interactions] | Low throughput | no | yes |
ITA2_HUMAN | [view interactions] | Low throughput | no | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IL1A_HUMAN | [view interactions] | Low throughput | no | no |
SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TEN3_HUMAN | [view interactions] | High throughput | no | yes |
TAB1_HUMAN | [view interactions] | High throughput | no | yes |
NCS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K7_HUMAN | [view interactions] | High throughput | no | yes |
ZCHC3_HUMAN | [view interactions] | High throughput | no | no |
UMAD1_HUMAN | [view interactions] | High throughput | no | yes |
UEVLD_HUMAN | [view interactions] | High throughput | no | yes |
S1PR2_HUMAN | [view interactions] | High throughput | no | no |
CRCM1_HUMAN | [view interactions] | High throughput | no | yes |
FZD7_HUMAN | [view interactions] | High throughput | no | yes |
DNJB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OTU1_HUMAN | [view interactions] | High throughput | no | yes |
ZBT32_HUMAN | [view interactions] | High throughput | no | yes |
PCH2_HUMAN | [view interactions] | High throughput | no | no |
UBP54_HUMAN | [view interactions] | High throughput | no | yes |
KRA62_HUMAN | [view interactions] | High throughput | no | no |
KRA71_HUMAN | [view interactions] | High throughput | no | no |
FYB1_HUMAN | [view interactions] | High throughput | no | no |
SCNBA_HUMAN | [view interactions] | High throughput | no | no |
ZN106_HUMAN | [view interactions] | High throughput | no | no |
STK24_HUMAN | [view interactions] | High throughput | no | yes |
CUX1_HUMAN | [view interactions] | High throughput | no | yes |
TEKT4_HUMAN | [view interactions] | High throughput | no | no |
ASAP2_HUMAN | [view interactions] | High throughput | no | yes |
CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PACA_HUMAN | [view interactions] | High throughput | no | no |
BRE1A_HUMAN | [view interactions] | High throughput | no | yes |
AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SURF6_HUMAN | [view interactions] | High throughput | no | yes |
CAN13_HUMAN | [view interactions] | High throughput | no | yes |
AURKB_HUMAN | [view interactions] | High throughput | no | yes |
CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TLR3_HUMAN | [view interactions] | High throughput | no | yes |
RABX5_HUMAN | [view interactions] | High throughput | no | no |
RBTN2_HUMAN | [view interactions] | High throughput | no | yes |
SPAT2_HUMAN | [view interactions] | High throughput | no | yes |
WDR82_HUMAN | [view interactions] | High throughput | no | no |
UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSNAX_HUMAN | [view interactions] | High throughput | no | yes |
TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIGAR_HUMAN | [view interactions] | High throughput | no | yes |
RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RN114_HUMAN | [view interactions] | High throughput | no | no |
RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
PSD13_HUMAN | [view interactions] | High throughput | no | yes |
PSD12_HUMAN | [view interactions] | High throughput | no | yes |
PSB3_HUMAN | [view interactions] | High throughput | no | yes |
PSB2_HUMAN | [view interactions] | High throughput | no | yes |
PSA7_HUMAN | [view interactions] | High throughput | no | yes |
PSA6_HUMAN | [view interactions] | High throughput | no | yes |
PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA3_HUMAN | [view interactions] | High throughput | no | no |
PSA1_HUMAN | [view interactions] | High throughput | no | yes |
PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRDC1_HUMAN | [view interactions] | High throughput | no | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGTB2_HUMAN | [view interactions] | High throughput | no | yes |
PGAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
NEK7_HUMAN | [view interactions] | High throughput | no | yes |
NANP_HUMAN | [view interactions] | High throughput | no | no |
NAA10_HUMAN | [view interactions] | High throughput | no | yes |
METH_HUMAN | [view interactions] | High throughput | no | yes |
M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GET4_HUMAN | [view interactions] | High throughput | no | yes |
EPN4_HUMAN | [view interactions] | High throughput | no | yes |
EMD_HUMAN | [view interactions] | High throughput | no | yes |
DECR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DCA12_HUMAN | [view interactions] | High throughput | no | yes |
STEEP_HUMAN | [view interactions] | High throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCHL_HUMAN | [view interactions] | High throughput | no | yes |
CBR3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
ADIPO_HUMAN | [view interactions] | High throughput | no | no |
GFRP_HUMAN | [view interactions] | High throughput | no | no |
F91A1_HUMAN | [view interactions] | High throughput | no | yes |
SATB2_HUMAN | [view interactions] | High throughput | no | yes |
TRI65_HUMAN | [view interactions] | High throughput | no | yes |
MIO_HUMAN | [view interactions] | High throughput | no | yes |
O52N5_HUMAN | [view interactions] | High throughput | no | no |
IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
CSRN1_HUMAN | [view interactions] | High throughput | no | no |
MTA70_HUMAN | [view interactions] | High throughput | no | no |
DMWD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZN703_HUMAN | [view interactions] | High throughput | no | yes |
O52N4_HUMAN | [view interactions] | High throughput | no | no |
HIPK1_HUMAN | [view interactions] | High throughput | no | no |
MED12_HUMAN | [view interactions] | High throughput | no | yes |
ZN609_HUMAN | [view interactions] | High throughput | no | yes |
ZN507_HUMAN | [view interactions] | High throughput | no | no |
BCOR_HUMAN | [view interactions] | High throughput | no | no |
TRI33_HUMAN | [view interactions] | High throughput | no | yes |
WDR11_HUMAN | [view interactions] | High throughput | no | yes |
NIT1_HUMAN | [view interactions] | High throughput | no | yes |
SAM11_HUMAN | [view interactions] | High throughput | no | no |
ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATX2_HUMAN | [view interactions] | High throughput | no | yes |
TCAB1_HUMAN | [view interactions] | High throughput | no | yes |
PRI2_HUMAN | [view interactions] | High throughput | no | no |
TCAF1_HUMAN | [view interactions] | High throughput | no | no |
QRIC1_HUMAN | [view interactions] | High throughput | no | yes |
C19L1_HUMAN | [view interactions] | High throughput | no | yes |
EPHA2_HUMAN | [view interactions] | High throughput | no | no |
LAR4B_HUMAN | [view interactions] | High throughput | no | yes |
NISCH_HUMAN | [view interactions] | High throughput | no | yes |
RD23A_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTC1_HUMAN | [view interactions] | High throughput | no | no |
GSE1_HUMAN | [view interactions] | High throughput | no | yes |
TBB8_HUMAN | [view interactions] | High throughput | no | no |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
AGO2_HUMAN | [view interactions] | High throughput | no | yes |
TNR6A_HUMAN | [view interactions] | High throughput | no | yes |
FITM2_HUMAN | [view interactions] | High throughput | no | no |
ATG12_HUMAN | [view interactions] | High throughput | no | yes |
TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
THIOM_HUMAN | [view interactions] | High throughput | no | yes |
AP2C_HUMAN | [view interactions] | High throughput | no | no |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNR3_HUMAN | [view interactions] | High throughput | no | yes |
LIPG_HUMAN | [view interactions] | High throughput | no | no |
GRIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
BIRC3_HUMAN | [view interactions] | High throughput | no | no |
MALT1_HUMAN | [view interactions] | High throughput | no | no |
BCL10_HUMAN | [view interactions] | High throughput | no | yes |
IKKB_HUMAN | [view interactions] | High throughput | no | yes |
IKKA_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VP37D_HUMAN | [view interactions] | High throughput | no | no |
SEM4G_HUMAN | [view interactions] | High throughput | no | yes |
MOXD1_HUMAN | [view interactions] | High throughput | no | no |
MEAK7_HUMAN | [view interactions] | High throughput | no | yes |
PDPN_HUMAN | [view interactions] | High throughput | no | no |
MKRN4_HUMAN | [view interactions] | High throughput | no | no |
MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
RTL6_HUMAN | [view interactions] | High throughput | no | yes |
HPRT_HUMAN | [view interactions] | High throughput | no | yes |
ULBP3_HUMAN | [view interactions] | High throughput | no | yes |
TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
GDIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ULK3_HUMAN | [view interactions] | High throughput | no | yes |
TAB2_HUMAN | [view interactions] | High throughput | no | yes |
DYR_HUMAN | [view interactions] | High throughput | no | yes |
RIPK1_HUMAN | [view interactions] | Computational | no | yes |
XIAP_HUMAN | [view interactions] | Computational | no | yes |
UBP2_HUMAN | [view interactions] | Computational | no | yes |
RIPK2_HUMAN | [view interactions] | Computational | no | yes |
UBP4_HUMAN | [view interactions] | Computational | no | no |
SPA2L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
OTU7B_HUMAN | [view interactions] | Computational | no | yes |
RACK1_HUMAN | [view interactions] | Computational | no | yes |
TRADD_HUMAN | [view interactions] | Computational | no | yes |
UBP21_HUMAN | [view interactions] | Computational | no | no |