PGAM5_HUMAN
Evidence for PS localization
Functions
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002824 | DEG_Kelch_Keap1_1 | DEG | 77 | 82 | - |
| ELMI002824 | DEG_Kelch_Keap1_1 | DEG | 77 | 82 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PGAM5_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 24.5614 | 4 | no |
| GO:0046872 | metal ion binding | 24.5614 | 5 | no |
| GO:0000166 | nucleotide binding | 22.8070 | 4 | no |
| GO:0043168 | anion binding | 22.8070 | 4 | no |
| GO:0003723 | RNA binding | 22.8070 | 4 | no |
| GO:0017076 | purine nucleotide binding | 21.0526 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 21.0526 | 4 | no |
| GO:0004722 | protein serine/threonine phosphatase activity | 5.2632 | 4 | yes |
| GO:0005096 | GTPase activator activity | 5.2632 | 4 | yes |
| GO:0016791 | phosphatase activity | 5.2632 | 5 | yes |
| GO:0017018 | myosin phosphatase activity | 5.2632 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 5.2632 | 4 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 5.2632 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PGAM5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.4035 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 56.1404 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.3684 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.6140 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 45.6140 | 4 | no |
| GO:0006996 | organelle organization | 43.8596 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.8596 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.1053 | 4 | no |
| GO:0008104 | protein localization | 38.5965 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.8421 | 5 | no |
| GO:0009966 | regulation of signal transduction | 36.8421 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 36.8421 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.8421 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.8421 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 36.8421 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.8421 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 35.0877 | 5 | no |
| GO:0022607 | cellular component assembly | 35.0877 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 35.0877 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.5789 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.5789 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 29.8246 | 5 | no |
| GO:0023057 | negative regulation of signaling | 29.8246 | 4 | no |
| GO:0033043 | regulation of organelle organization | 29.8246 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 28.0702 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.0702 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 28.0702 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 28.0702 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.0702 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 28.0702 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.0702 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.3158 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.3158 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.3158 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.3158 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.3158 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.3158 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 26.3158 | 7 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.5614 | 6 | no |
| GO:0080134 | regulation of response to stress | 24.5614 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 24.5614 | 5 | no |
| GO:0023056 | positive regulation of signaling | 24.5614 | 4 | no |
| GO:0043933 | protein-containing complex organization | 24.5614 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.5614 | 5 | no |
| GO:0071702 | organic substance transport | 24.5614 | 4 | no |
| GO:0051049 | regulation of transport | 24.5614 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.5614 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 24.5614 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 24.5614 | 6 | no |
| GO:0007010 | cytoskeleton organization | 22.8070 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 22.8070 | 5 | no |
| GO:0031399 | regulation of protein modification process | 22.8070 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.8070 | 4 | no |
| GO:0071705 | nitrogen compound transport | 22.8070 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.8070 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 22.8070 | 4 | yes |
| GO:0036211 | protein modification process | 21.0526 | 4 | no |
| GO:0043412 | macromolecule modification | 21.0526 | 4 | no |
| GO:0030030 | cell projection organization | 21.0526 | 4 | no |
| GO:0033365 | protein localization to organelle | 21.0526 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 21.0526 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.0526 | 5 | no |
| GO:0009894 | regulation of catabolic process | 21.0526 | 4 | no |
| GO:0071310 | cellular response to organic substance | 21.0526 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 19.2982 | 4 | yes |
| GO:0010638 | positive regulation of organelle organization | 17.5439 | 6 | yes |
| GO:0016236 | macroautophagy | 10.5263 | 4 | yes |
| GO:0010821 | regulation of mitochondrion organization | 8.7719 | 6 | yes |
| GO:0070266 | necroptotic process | 5.2632 | 5 | yes |
| GO:0090140 | regulation of mitochondrial fission | 5.2632 | 5 | yes |
| GO:0090141 | positive regulation of mitochondrial fission | 5.2632 | 5 | yes |
| GO:0097300 | programmed necrotic cell death | 5.2632 | 4 | yes |
| GO:0120161 | regulation of cold-induced thermogenesis | 3.5088 | 4 | yes |
| GO:0120163 | negative regulation of cold-induced thermogenesis | 3.5088 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KEAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| RIPK3_HUMAN | [view interactions] | Low throughput | no | no |
| M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
| MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| RBX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PINK1_HUMAN | [view interactions] | Low throughput | no | yes |
| NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
| XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
| PGAM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RNF5_HUMAN | [view interactions] | Low throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EMC7_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PKP2_HUMAN | [view interactions] | High throughput | no | yes |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COIA1_HUMAN | [view interactions] | High throughput | no | no |
| SLX4_HUMAN | [view interactions] | High throughput | no | yes |
| DJC10_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| GALT2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSB10_HUMAN | [view interactions] | High throughput | no | no |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| RNS10_HUMAN | [view interactions] | High throughput | no | no |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGN2_HUMAN | [view interactions] | High throughput | no | yes |
| MGN_HUMAN | [view interactions] | High throughput | no | yes |
| MLKL_HUMAN | [view interactions] | High throughput | no | no |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXPH5_HUMAN | [view interactions] | High throughput | no | no |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| Z3H7A_HUMAN | [view interactions] | High throughput | no | no |
| TTL12_HUMAN | [view interactions] | High throughput | no | yes |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| CD2AP_HUMAN | [view interactions] | High throughput | no | no |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| MYH7B_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| ZSC26_HUMAN | [view interactions] | High throughput | no | no |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| SMC1A_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| KBTB4_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BLK_HUMAN | [view interactions] | High throughput | no | no |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP3_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| LRC8E_HUMAN | [view interactions] | High throughput | no | no |
| MICA3_HUMAN | [view interactions] | High throughput | no | yes |
| TENS2_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| SOX6_HUMAN | [view interactions] | High throughput | no | yes |
| RNPS1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CNDD3_HUMAN | [view interactions] | High throughput | no | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| CE192_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| POC5_HUMAN | [view interactions] | High throughput | no | yes |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT16_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3A_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| HDGF_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| PHS_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RON_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| BARD1_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASB3_HUMAN | [view interactions] | High throughput | no | yes |
| ASB10_HUMAN | [view interactions] | High throughput | no | no |
| ASB14_HUMAN | [view interactions] | High throughput | no | no |
| ASB18_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| NKX21_HUMAN | [view interactions] | High throughput | no | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CLC14_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| DPOD1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| HABP4_HUMAN | [view interactions] | High throughput | no | yes |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR4_HUMAN | [view interactions] | High throughput | no | no |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD8_HUMAN | [view interactions] | High throughput | no | yes |
| BRD9_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB8_HUMAN | [view interactions] | High throughput | no | no |
| PO2F1_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI31_HUMAN | [view interactions] | High throughput | no | no |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD1_HUMAN | [view interactions] | High throughput | no | yes |
| R113A_HUMAN | [view interactions] | High throughput | no | yes |
| GATA4_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| RECQ1_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
| A16A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |