Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IF4A3_HUMAN

ATP-dependent RNA helicase (PubMed). Involved in pre-mRNA splicing as component of the spliceosome (PubMed, PubMed, PubMed, PubMed, PubMed). Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Its RNA-dependent ATPase and RNA-helicase activities are induced by CASC3, but abolished in presence of the MAGOH-RBM8A heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The inhibition of ATPase activity by the MAGOH-RBM8A heterodimer increases the RNA-binding affinity of the EJC. Involved in translational enhancement of spliced mRNAs after formation of the 80S ribosome complex. Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions. Shows higher affinity for single-stranded RNA in an ATP-bound core EJC complex than after the ATP is hydrolyzed. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the function is different from the established EJC assembly (PubMed). Involved in craniofacial development (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in IF4A3_HUMAN
GO:0003723 RNA binding 61.7886 4 yes
GO:0017076 purine nucleotide binding 24.3902 4 yes
GO:0032555 purine ribonucleotide binding 24.3902 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 24.3902 4 yes
GO:0045296 cadherin binding 21.1382 4 no
GO:0005524 ATP binding 19.5122 5 yes
GO:0030554 adenyl nucleotide binding 19.5122 5 yes
GO:0032559 adenyl ribonucleotide binding 19.5122 5 yes
GO:0003729 mRNA binding 18.6992 5 yes
GO:0016462 pyrophosphatase activity 13.8211 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 13.8211 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 13.8211 6 yes
GO:0016887 ATP hydrolysis activity 8.9431 7 yes
GO:0003727 single-stranded RNA binding 6.5041 5 yes
GO:0035613 RNA stem-loop binding 4.0650 5 yes
GO:0070717 poly-purine tract binding 4.0650 6 yes
GO:0008143 poly(A) binding 3.2520 7 yes
GO:0035368 selenocysteine insertion sequence binding 1.6260 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IF4A3_HUMAN
GO:0060255 regulation of macromolecule metabolic process 53.6585 4 yes
GO:0080090 regulation of primary metabolic process 52.0325 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 52.0325 4 yes
GO:0031323 regulation of cellular metabolic process 51.2195 4 yes
GO:0048522 positive regulation of cellular process 51.2195 4 yes
GO:0048523 negative regulation of cellular process 49.5935 4 yes
GO:0010468 regulation of gene expression 44.7154 5 yes
GO:0051128 regulation of cellular component organization 42.2764 4 no
GO:0009889 regulation of biosynthetic process 37.3984 4 yes
GO:0009893 positive regulation of metabolic process 37.3984 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 37.3984 5 yes
GO:0031326 regulation of cellular biosynthetic process 37.3984 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 36.5854 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 35.7724 5 yes
GO:0051246 regulation of protein metabolic process 34.9593 5 yes
GO:0006996 organelle organization 34.1463 4 no
GO:0009892 negative regulation of metabolic process 34.1463 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 34.1463 5 yes
GO:0051252 regulation of RNA metabolic process 33.3333 5 yes
GO:0031325 positive regulation of cellular metabolic process 32.5203 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 31.7073 5 yes
GO:0010646 regulation of cell communication 31.7073 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 30.8943 5 yes
GO:0090304 nucleic acid metabolic process 30.0813 4 yes
GO:0031324 negative regulation of cellular metabolic process 30.0813 5 yes
GO:0009059 macromolecule biosynthetic process 28.4553 4 no
GO:0044271 cellular nitrogen compound biosynthetic process 28.4553 4 no
GO:0009966 regulation of signal transduction 28.4553 4 yes
GO:0022607 cellular component assembly 26.8293 4 no
GO:0043603 cellular amide metabolic process 26.8293 4 no
GO:0033043 regulation of organelle organization 26.0163 5 no
GO:0006518 peptide metabolic process 25.2033 4 no
GO:0034645 cellular macromolecule biosynthetic process 25.2033 4 no
GO:0043604 amide biosynthetic process 25.2033 5 no
GO:1901566 organonitrogen compound biosynthetic process 25.2033 4 no
GO:0016070 RNA metabolic process 25.2033 5 yes
GO:0071310 cellular response to organic substance 24.3902 4 yes
GO:0006412 translation 24.3902 4 no
GO:0043043 peptide biosynthetic process 24.3902 5 no
GO:0043412 macromolecule modification 24.3902 4 no
GO:0051130 positive regulation of cellular component organization 24.3902 5 no
GO:0002181 cytoplasmic translation 22.7642 5 no
GO:1903506 regulation of nucleic acid-templated transcription 22.7642 7 no
GO:2001141 regulation of RNA biosynthetic process 22.7642 6 no
GO:0006355 regulation of DNA-templated transcription 21.9512 6 no
GO:0036211 protein modification process 21.9512 4 no
GO:0006396 RNA processing 21.9512 6 yes
GO:0010628 positive regulation of gene expression 21.9512 6 yes
GO:0051247 positive regulation of protein metabolic process 21.9512 6 yes
GO:0009890 negative regulation of biosynthetic process 21.1382 5 yes
GO:0010941 regulation of cell death 20.3252 4 no
GO:1902531 regulation of intracellular signal transduction 20.3252 5 no
GO:0009891 positive regulation of biosynthetic process 20.3252 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 20.3252 6 yes
GO:0071702 organic substance transport 19.5122 4 yes
GO:0071705 nitrogen compound transport 19.5122 4 yes
GO:0009894 regulation of catabolic process 19.5122 4 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 19.5122 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 19.5122 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 19.5122 6 yes
GO:0051248 negative regulation of protein metabolic process 18.6992 6 yes
GO:0010629 negative regulation of gene expression 17.8862 6 yes
GO:0010608 post-transcriptional regulation of gene expression 17.0732 6 yes
GO:0031329 regulation of cellular catabolic process 17.0732 5 yes
GO:0010648 negative regulation of cell communication 16.2602 5 yes
GO:0023057 negative regulation of signaling 16.2602 4 yes
GO:2000112 regulation of cellular macromolecule biosynthetic process 15.4472 6 yes
GO:0016071 mRNA metabolic process 15.4472 6 yes
GO:0048585 negative regulation of response to stimulus 15.4472 4 yes
GO:0006417 regulation of translation 14.6341 6 yes
GO:0009968 negative regulation of signal transduction 14.6341 5 yes
GO:0034248 regulation of cellular amide metabolic process 14.6341 5 yes
GO:1903311 regulation of mRNA metabolic process 13.8211 6 yes
GO:0008380 RNA splicing 13.8211 7 yes
GO:0006397 mRNA processing 12.1951 7 yes
GO:0034660 ncRNA metabolic process 12.1951 6 yes
GO:0014070 response to organic cyclic compound 11.3821 4 yes
GO:0034470 ncRNA processing 11.3821 7 yes
GO:0000375 RNA splicing, via transesterification reactions 10.5691 8 yes
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 10.5691 9 yes
GO:0000398 mRNA splicing, via spliceosome 10.5691 8 yes
GO:0009057 macromolecule catabolic process 8.9431 4 yes
GO:0034250 positive regulation of cellular amide metabolic process 8.9431 6 yes
GO:0045727 positive regulation of translation 8.9431 7 yes
GO:0099177 regulation of trans-synaptic signaling 8.1301 4 yes
GO:0006364 rRNA processing 8.1301 8 yes
GO:0016072 rRNA metabolic process 8.1301 7 yes
GO:0044265 cellular macromolecule catabolic process 8.1301 4 yes
GO:0050804 modulation of chemical synaptic transmission 8.1301 5 yes
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 7.3171 7 yes
GO:0015931 nucleobase-containing compound transport 7.3171 5 yes
GO:0017148 negative regulation of translation 7.3171 7 yes
GO:0034249 negative regulation of cellular amide metabolic process 7.3171 6 yes
GO:0061013 regulation of mRNA catabolic process 7.3171 6 yes
GO:0070848 response to growth factor 7.3171 4 yes
GO:0071363 cellular response to growth factor stimulus 6.5041 5 yes
GO:1901361 organic cyclic compound catabolic process 6.5041 4 yes
GO:0006401 RNA catabolic process 6.5041 5 yes
GO:0006402 mRNA catabolic process 6.5041 6 yes
GO:0019439 aromatic compound catabolic process 6.5041 4 yes
GO:0034655 nucleobase-containing compound catabolic process 6.5041 4 yes
GO:0044270 cellular nitrogen compound catabolic process 6.5041 4 yes
GO:0046700 heterocycle catabolic process 6.5041 4 yes
GO:0050657 nucleic acid transport 6.5041 6 yes
GO:0050658 RNA transport 6.5041 4 yes
GO:0071241 cellular response to inorganic substance 5.6911 4 yes
GO:0051028 mRNA transport 5.6911 5 yes
GO:0000956 nuclear-transcribed mRNA catabolic process 4.8780 7 yes
GO:0044057 regulation of system process 4.8780 4 yes
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 4.0650 8 yes
GO:0050890 cognition 4.0650 4 yes
GO:0051100 negative regulation of binding 4.0650 4 yes
GO:1902415 regulation of mRNA binding 3.2520 5 yes
GO:1905214 regulation of RNA binding 3.2520 4 yes
GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.2520 7 yes
GO:0050805 negative regulation of synaptic transmission 3.2520 5 yes
GO:1990090 cellular response to nerve growth factor stimulus 2.4390 4 yes
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus 2.4390 5 yes
GO:0007612 learning 2.4390 4 yes
GO:0008306 associative learning 2.4390 5 yes
GO:0031644 regulation of nervous system process 2.4390 5 yes
GO:0048562 embryonic organ morphogenesis 2.4390 4 yes
GO:0048704 embryonic skeletal system morphogenesis 2.4390 5 yes
GO:0048705 skeletal system morphogenesis 2.4390 4 yes
GO:0072714 response to selenite ion 1.6260 4 yes
GO:0072715 cellular response to selenite ion 1.6260 5 yes
GO:0090394 negative regulation of excitatory postsynaptic potential 1.6260 5 yes
GO:0098815 modulation of excitatory postsynaptic potential 1.6260 4 yes
GO:0099170 postsynaptic modulation of chemical synaptic transmission 1.6260 6 yes
GO:0099547 regulation of translation at synapse, modulating synaptic transmission 1.6260 6 yes
GO:0099578 regulation of translation at postsynapse, modulating synaptic transmission 1.6260 7 yes
GO:0140243 regulation of translation at synapse 1.6260 7 yes
GO:0140245 regulation of translation at postsynapse 1.6260 8 yes
GO:1904569 regulation of selenocysteine incorporation 1.6260 8 yes
GO:1904570 negative regulation of selenocysteine incorporation 1.6260 9 yes
GO:1904572 negative regulation of mRNA binding 1.6260 6 yes
GO:1904573 regulation of selenocysteine insertion sequence binding 1.6260 6 yes
GO:1904574 negative regulation of selenocysteine insertion sequence binding 1.6260 7 yes
GO:1905215 negative regulation of RNA binding 1.6260 5 yes
GO:0006448 regulation of translational elongation 1.6260 7 yes
GO:0045900 negative regulation of translational elongation 1.6260 8 yes
GO:0048701 embryonic cranial skeleton morphogenesis 1.6260 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in IF4A3_HUMAN
DOID:1289 neurodegenerative disease 1.6260 4 no
DOID:331 central nervous system disease 1.6260 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NOM1_HUMAN [view interactions] Low throughput no yes
NCBP1_HUMAN [view interactions] Low throughput no yes
IF4G1_HUMAN [view entry] [view interactions] Low throughput yes yes
NXF1_HUMAN [view interactions] Low throughput no yes
PARK7_HUMAN [view entry] [view interactions] Low throughput yes yes
ACADV_HUMAN [view interactions] Low throughput no yes
CWC27_HUMAN [view interactions] Low throughput no yes
IF4A3_HUMAN [view entry] [view interactions] Low throughput yes yes
CWC22_HUMAN [view interactions] Low throughput no yes
RBM8A_HUMAN [view interactions] Low throughput no yes
MGN_HUMAN [view interactions] Low throughput no yes
AGO2_HUMAN [view interactions] Low throughput no yes
CASC3_HUMAN [view interactions] Low throughput no yes
REN3B_HUMAN [view interactions] Low throughput no yes
SRSF1_HUMAN [view interactions] Low throughput no yes
SAP18_HUMAN [view interactions] Low throughput no yes
RNPS1_HUMAN [view interactions] Low throughput no yes
PDIP3_HUMAN [view interactions] Low throughput no no
ROA1_HUMAN [view entry] [view interactions] Low throughput yes yes
THOC4_HUMAN [view interactions] Low throughput no no
EF2K_HUMAN [view entry] [view interactions] Low throughput yes no
HNRPC_HUMAN [view interactions] Low throughput no yes
SRSF7_HUMAN [view interactions] Low throughput no yes
UIF_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
SRRM1_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
RL13A_HUMAN [view entry] [view interactions] High throughput yes yes
DOC11_HUMAN [view interactions] High throughput no yes
K1C14_HUMAN [view interactions] High throughput no no
UBR5_HUMAN [view interactions] High throughput no no
K1C16_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
RL24_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
KI20A_HUMAN [view interactions] High throughput no yes
K1C9_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
PRC1_HUMAN [view interactions] High throughput no yes
SRSF3_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
PGAM5_HUMAN [view entry] [view interactions] High throughput yes yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
PPIE_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
TRA2A_HUMAN [view interactions] High throughput no yes
RBM45_HUMAN [view interactions] High throughput no yes
DHX15_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
RALY_HUMAN [view interactions] High throughput no yes
RBBP6_HUMAN [view interactions] High throughput no yes
SF3B3_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
PLRG1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
DX39A_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
ZC11A_HUMAN [view interactions] High throughput no yes
SC23B_HUMAN [view interactions] High throughput no yes
PRP17_HUMAN [view interactions] High throughput no no
SC23A_HUMAN [view entry] [view interactions] High throughput yes yes
SPF27_HUMAN [view interactions] High throughput no yes
SNX12_HUMAN [view entry] [view interactions] High throughput yes yes
ZC3HE_HUMAN [view interactions] High throughput no yes
AASD1_HUMAN [view interactions] High throughput no yes
THOC2_HUMAN [view interactions] High throughput no yes
MDC1_HUMAN [view interactions] High throughput no yes
SART3_HUMAN [view interactions] High throughput no yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
THOC1_HUMAN [view interactions] High throughput no yes
CUL9_HUMAN [view interactions] High throughput no no
THOC5_HUMAN [view interactions] High throughput no no
NALP7_HUMAN [view interactions] High throughput no no
THOC7_HUMAN [view interactions] High throughput no yes
DDB1_HUMAN [view interactions] High throughput no yes
TZAP_HUMAN [view interactions] High throughput no no
RBCC1_HUMAN [view interactions] High throughput no no
UBA6_HUMAN [view interactions] High throughput no no
BAG1_HUMAN [view interactions] High throughput no yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
DDX41_HUMAN [view interactions] High throughput no yes
CPSF6_HUMAN [view interactions] High throughput no yes
VTI1B_HUMAN [view entry] [view interactions] High throughput yes yes
DDX21_HUMAN [view interactions] High throughput no yes
IF4A1_HUMAN [view interactions] High throughput no no
RENT2_HUMAN [view interactions] High throughput no no
LZTR1_HUMAN [view interactions] High throughput no no
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
SNIP1_HUMAN [view interactions] High throughput no no
PSPC1_HUMAN [view interactions] High throughput no yes
SARNP_HUMAN [view interactions] High throughput no yes
RBM33_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
RS16_HUMAN [view entry] [view interactions] High throughput yes yes
RRP1B_HUMAN [view interactions] High throughput no yes
SF3A2_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
RU2B_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
RU1C_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
RUXF_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
SRP09_HUMAN [view interactions] High throughput no no
SH2D3_HUMAN [view interactions] High throughput no no
SSRP1_HUMAN [view interactions] High throughput no yes
SPT5H_HUMAN [view interactions] High throughput no yes
NCBP3_HUMAN [view interactions] High throughput no yes
TOP1_HUMAN [view interactions] High throughput no yes
NCBP2_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
RIT1_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
OTUD4_HUMAN [view interactions] High throughput no yes
COQ2_HUMAN [view interactions] High throughput no yes
ERCC6_HUMAN [view interactions] High throughput no no
COX15_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
RL37A_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
PRP6_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPR_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
SNUT1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
PRPF3_HUMAN [view interactions] High throughput no yes
IF4B_HUMAN [view entry] [view interactions] High throughput yes yes
PR40A_HUMAN [view interactions] High throughput no yes
TFR1_HUMAN [view interactions] High throughput no yes
WDR18_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
GNL3_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
SRP19_HUMAN [view interactions] High throughput no yes
S10A9_HUMAN [view entry] [view interactions] High throughput yes no
HMGA2_HUMAN [view interactions] High throughput no yes
WIPF2_HUMAN [view entry] [view interactions] High throughput yes yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
SMCA5_HUMAN [view interactions] High throughput no yes
HTRA4_HUMAN [view interactions] High throughput no no
NUP62_HUMAN [view interactions] High throughput no yes
TBX5_HUMAN [view interactions] High throughput no no
SNF5_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
ROA0_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
LBR_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
MIRO2_HUMAN [view entry] [view interactions] High throughput yes yes
MEIKN_HUMAN [view interactions] High throughput no no
PSIP1_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
SYAC_HUMAN [view interactions] High throughput no yes
HMGB1_HUMAN [view interactions] High throughput no yes
AN32A_HUMAN [view interactions] High throughput no yes
IPO11_HUMAN [view interactions] High throughput no yes
BMI1_HUMAN [view interactions] High throughput no yes
NPL4_HUMAN [view interactions] High throughput no yes
RYBP_HUMAN [view interactions] High throughput no no
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
PDCD4_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
CDA7L_HUMAN [view interactions] High throughput no yes
PLIN3_HUMAN [view interactions] High throughput no yes
ZXDB_HUMAN [view interactions] High throughput no yes
SRP14_HUMAN [view interactions] High throughput no no
TRI27_HUMAN [view interactions] High throughput no yes
RD23B_HUMAN [view interactions] High throughput no yes
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
KCRM_HUMAN [view interactions] High throughput no no
NIF3L_HUMAN [view interactions] High throughput no yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
IF4A2_HUMAN [view entry] [view interactions] High throughput yes yes
MEOX1_HUMAN [view interactions] High throughput no no
MTREX_HUMAN [view interactions] High throughput no yes
EHMT2_HUMAN [view entry] [view interactions] High throughput yes yes
PP6R3_HUMAN [view interactions] High throughput no yes
CC174_HUMAN [view interactions] High throughput no yes
RRS1_HUMAN [view interactions] High throughput no yes
DDT4L_HUMAN [view interactions] High throughput no no
STK25_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
TIPRL_HUMAN [view interactions] High throughput no yes
DDX56_HUMAN [view interactions] High throughput no yes
PYRG2_HUMAN [view interactions] High throughput no yes
DRG2_HUMAN [view interactions] High throughput no yes
IF2A_HUMAN [view entry] [view interactions] High throughput yes yes
VRTN_HUMAN [view interactions] High throughput no no
LSM2_HUMAN [view interactions] High throughput no yes
PSA1_HUMAN [view interactions] High throughput no yes
LSM3_HUMAN [view interactions] High throughput no yes
CNKR3_HUMAN [view interactions] High throughput no yes
RUXE_HUMAN [view interactions] High throughput no no
RPB7_HUMAN [view interactions] High throughput no yes
DENR_HUMAN [view interactions] High throughput no yes
RPAC1_HUMAN [view interactions] High throughput no no
5HT6R_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
KIF1C_HUMAN [view interactions] High throughput no yes
FRG1_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
CK068_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
PPWD1_HUMAN [view interactions] High throughput no yes
SRPK1_HUMAN [view interactions] High throughput no yes
PPIL3_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
SF3A3_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CS047_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CATIN_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
ESF1_HUMAN [view interactions] High throughput no yes
ZN335_HUMAN [view interactions] High throughput no no
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
NECD_HUMAN [view interactions] High throughput no no
GCFC2_HUMAN [view interactions] High throughput no no
PAX4_HUMAN [view interactions] High throughput no no
HNRL1_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
NOL10_HUMAN [view interactions] High throughput no yes
REL_HUMAN [view interactions] High throughput no yes
PARN_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
PR38A_HUMAN [view interactions] High throughput no no
CARD9_HUMAN [view interactions] High throughput no no
RBM26_HUMAN [view interactions] High throughput no yes
ANKH1_HUMAN [view interactions] High throughput no yes
SLU7_HUMAN [view interactions] High throughput no yes
CTND1_HUMAN [view entry] [view interactions] High throughput yes no
WRN_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
AK17A_HUMAN [view interactions] High throughput no no
CPSF5_HUMAN [view interactions] High throughput no yes
BTAF1_HUMAN [view interactions] High throughput no no
EIF3G_HUMAN [view interactions] High throughput no yes
DACH1_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
RED_HUMAN [view interactions] High throughput no yes
TCEA2_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
HDAC5_HUMAN [view interactions] High throughput no yes
GWL_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
MYBB_HUMAN [view interactions] High throughput no yes
STF1_HUMAN [view interactions] High throughput no no
PTBP3_HUMAN [view interactions] High throughput no no
SMAD4_HUMAN [view interactions] High throughput no yes
WDR36_HUMAN [view interactions] High throughput no yes
GRK5_HUMAN [view interactions] High throughput no yes
TDRD3_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
BMS1_HUMAN [view interactions] High throughput no yes
RENT1_HUMAN [view entry] [view interactions] High throughput yes yes
RT29_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
GPTC8_HUMAN [view interactions] High throughput no yes
SRSF5_HUMAN [view interactions] High throughput no yes
INT1_HUMAN [view interactions] High throughput no yes
TSN_HUMAN [view interactions] High throughput no yes
MTA70_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
PCF11_HUMAN [view interactions] High throughput no no
ACTC_HUMAN [view interactions] High throughput no no
SUGP1_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
TCF20_HUMAN [view interactions] High throughput no yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
UT14A_HUMAN [view interactions] High throughput no yes
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
ZN451_HUMAN [view entry] [view interactions] High throughput yes no
K1C10_HUMAN [view interactions] High throughput no no
ZN629_HUMAN [view interactions] High throughput no no
K1C19_HUMAN [view interactions] High throughput no no
CCAR2_HUMAN [view interactions] High throughput no yes
K22E_HUMAN [view interactions] High throughput no no
MFAP1_HUMAN [view interactions] High throughput no yes
K2C5_HUMAN [view entry] [view interactions] High throughput yes no
NOP14_HUMAN [view interactions] High throughput no yes
K2C6B_HUMAN [view interactions] High throughput no no
RBM20_HUMAN [view interactions] High throughput no no
K2C71_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
K2C75_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
SPI2A_HUMAN [view interactions] High throughput no no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
SPIN1_HUMAN [view interactions] High throughput no no
SPTN1_HUMAN [view entry] [view interactions] High throughput yes yes
SPTB2_HUMAN [view entry] [view interactions] High throughput yes yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
MYH10_HUMAN [view entry] [view interactions] High throughput yes yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
POTEJ_HUMAN [view interactions] High throughput no no
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
ICLN_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
ADT2_HUMAN [view entry] [view interactions] High throughput yes yes
BLM_HUMAN [view interactions] High throughput no yes
BOLA2_HUMAN [view interactions] High throughput no yes
AGO1_HUMAN [view interactions] High throughput no no
DOCK4_HUMAN [view entry] [view interactions] High throughput yes no
F263_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
REN3A_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
SMG1_HUMAN [view interactions] High throughput no yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
FTM_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
TR150_HUMAN [view interactions] High throughput no yes
JAK1_HUMAN [view interactions] High throughput no yes
MOB2_HUMAN [view interactions] High throughput no no
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
PPM1B_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
RAN_HUMAN [view entry] [view interactions] High throughput yes no
REST_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
ST38L_HUMAN [view entry] [view interactions] High throughput yes yes
SNR40_HUMAN [view interactions] High throughput no yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
CWC15_HUMAN [view interactions] High throughput no yes
FBRL_HUMAN [view interactions] High throughput no yes
RL17_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
H12_HUMAN [view interactions] High throughput no yes
RL21_HUMAN [view entry] [view interactions] High throughput yes yes
RL26_HUMAN [view entry] [view interactions] High throughput yes yes
H2A1D_HUMAN [view interactions] High throughput no yes
RL27A_HUMAN [view entry] [view interactions] High throughput yes yes
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
ERH_HUMAN [view interactions] High throughput no yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
SRSF9_HUMAN [view interactions] High throughput no yes
SMD1_HUMAN [view interactions] High throughput no yes
SRS12_HUMAN [view interactions] High throughput no no
SMD2_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
RBM10_HUMAN [view interactions] High throughput no yes
SFR19_HUMAN [view interactions] High throughput no yes
SCYL2_HUMAN [view interactions] High throughput no yes
AQR_HUMAN [view interactions] High throughput no no
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
DDX17_HUMAN [view entry] [view interactions] High throughput yes yes
RL3_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
YTDC1_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
MATR3_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
LN28B_HUMAN [view interactions] High throughput no no
PRP4B_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
SON_HUMAN [view interactions] High throughput no yes
HAUS1_HUMAN [view interactions] High throughput no yes
CRNL1_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
K2C1_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
SUZ12_HUMAN [view interactions] High throughput no no
RL13_HUMAN [view entry] [view interactions] High throughput yes yes
EED_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
RING2_HUMAN [view interactions] High throughput no yes
H31T_HUMAN [view interactions] High throughput no yes
LUZP4_HUMAN [view interactions] High throughput no no
YBOX3_HUMAN [view interactions] High throughput no yes
ABCE1_HUMAN [view interactions] High throughput no yes
ZC3HD_HUMAN [view interactions] High throughput no yes
EDA_HUMAN [view interactions] High throughput no no
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
SF3B1_HUMAN [view interactions] High throughput no yes
CEBPA_HUMAN [view interactions] High throughput no yes
ILF2_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
SRS10_HUMAN [view interactions] High throughput no yes
NKAP1_HUMAN [view interactions] High throughput no yes
TRA2B_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
UBE2A_HUMAN [view interactions] High throughput no no
SRSF2_HUMAN [view interactions] High throughput no yes
CLC14_HUMAN [view interactions] High throughput no yes
SF3A1_HUMAN [view interactions] High throughput no yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
RBM22_HUMAN [view interactions] High throughput no yes
API5_HUMAN [view interactions] High throughput no no
SYF1_HUMAN [view interactions] High throughput no no
HNF1B_HUMAN [view interactions] High throughput no no
PININ_HUMAN [view interactions] High throughput no yes
TBX3_HUMAN [view interactions] High throughput no no
CDC5L_HUMAN [view interactions] High throughput no yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
PURA2_HUMAN [view interactions] High throughput no yes
ANM1_HUMAN [view interactions] High throughput no yes
BMP4_HUMAN [view interactions] High throughput no no
H2B1C_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
YBOX1_HUMAN [view interactions] High throughput no yes
TGFB1_HUMAN [view interactions] High throughput no no
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
LAP2A_HUMAN [view interactions] High throughput no yes
SF3B2_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
ILF3_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
CCDC9_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
SRSF4_HUMAN [view interactions] High throughput no yes
CHD4_HUMAN [view interactions] High throughput no yes
CHTOP_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
PYM1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
HNRH2_HUMAN [view entry] [view interactions] High throughput yes yes
HERC2_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
H2A1A_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
HNRPF_HUMAN [view interactions] High throughput no yes
WDR76_HUMAN [view interactions] High throughput no no
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1B_HUMAN [view interactions] High throughput no yes
BCLF1_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT7A_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
NR2C2_HUMAN [view interactions] High throughput no yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
UCHL3_HUMAN [view interactions] High throughput no yes
SRSF8_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
PRP19_HUMAN [view interactions] High throughput no yes
OTUB2_HUMAN [view interactions] High throughput no no
MGN2_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
SNW1_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
U520_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
SRSF6_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
CMTR1_HUMAN [view interactions] High throughput no yes
SMD3_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
RSMB_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes