PRDX1_HUMAN
Evidence for PS localization
Functions
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRDX1_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 32.0388 | 4 | no |
| GO:0019900 | kinase binding | 26.2136 | 4 | no |
| GO:0003723 | RNA binding | 24.2718 | 4 | yes |
| GO:0019901 | protein kinase binding | 24.2718 | 5 | no |
| GO:0017076 | purine nucleotide binding | 21.3592 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 21.3592 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.3883 | 4 | no |
| GO:0045296 | cadherin binding | 15.5340 | 4 | yes |
| GO:0008379 | thioredoxin peroxidase activity | 4.8544 | 5 | yes |
| GO:0140824 | thioredoxin-dependent peroxiredoxin activity | 4.8544 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRDX1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.2816 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 56.3107 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 56.3107 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 56.3107 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 55.3398 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 55.3398 | 4 | no |
| GO:0010646 | regulation of cell communication | 49.5146 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 47.5728 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 47.5728 | 4 | no |
| GO:0010468 | regulation of gene expression | 44.6602 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 44.6602 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 40.7767 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.7767 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 40.7767 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.7767 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 39.8058 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 39.8058 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 39.8058 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 39.8058 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 39.8058 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.8350 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 38.8350 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 38.8350 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 38.8350 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 37.8641 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 35.9223 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 35.9223 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 35.9223 | 6 | no |
| GO:0006996 | organelle organization | 34.9515 | 4 | no |
| GO:0043412 | macromolecule modification | 34.9515 | 4 | no |
| GO:0036211 | protein modification process | 33.9806 | 4 | no |
| GO:0022607 | cellular component assembly | 32.0388 | 4 | no |
| GO:0010941 | regulation of cell death | 32.0388 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 31.0680 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 31.0680 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 29.1262 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.1553 | 6 | no |
| GO:0031399 | regulation of protein modification process | 28.1553 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.1553 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.1553 | 6 | no |
| GO:0071310 | cellular response to organic substance | 28.1553 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.1553 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 26.2136 | 7 | no |
| GO:0008104 | protein localization | 24.2718 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 24.2718 | 5 | no |
| GO:0023057 | negative regulation of signaling | 24.2718 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 24.2718 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 24.2718 | 7 | no |
| GO:0080134 | regulation of response to stress | 23.3010 | 4 | yes |
| GO:0051049 | regulation of transport | 23.3010 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.3010 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 23.3010 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 23.3010 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.3010 | 4 | no |
| GO:0043933 | protein-containing complex organization | 22.3301 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 22.3301 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.3301 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 22.3301 | 5 | no |
| GO:0043408 | regulation of MAPK cascade | 21.3592 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 21.3592 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.3592 | 5 | no |
| GO:0009894 | regulation of catabolic process | 21.3592 | 4 | no |
| GO:0033043 | regulation of organelle organization | 21.3592 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.3883 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.3883 | 6 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 20.3883 | 6 | no |
| GO:0060548 | negative regulation of cell death | 20.3883 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 20.3883 | 7 | no |
| GO:0043549 | regulation of kinase activity | 20.3883 | 5 | no |
| GO:0051338 | regulation of transferase activity | 20.3883 | 4 | no |
| GO:0051726 | regulation of cell cycle | 20.3883 | 4 | no |
| GO:0080135 | regulation of cellular response to stress | 19.4175 | 4 | yes |
| GO:0032872 | regulation of stress-activated MAPK cascade | 7.7670 | 6 | yes |
| GO:0060249 | anatomical structure homeostasis | 7.7670 | 4 | yes |
| GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 7.7670 | 5 | yes |
| GO:0001894 | tissue homeostasis | 5.8252 | 5 | yes |
| GO:0042743 | hydrogen peroxide metabolic process | 5.8252 | 4 | yes |
| GO:0042744 | hydrogen peroxide catabolic process | 4.8544 | 4 | yes |
| GO:0048872 | homeostasis of number of cells | 3.8835 | 4 | yes |
| GO:1901222 | regulation of NIK/NF-kappaB signaling | 3.8835 | 6 | yes |
| GO:0001895 | retina homeostasis | 2.9126 | 6 | yes |
| GO:0002449 | lymphocyte mediated immunity | 2.9126 | 4 | yes |
| GO:0006801 | superoxide metabolic process | 2.9126 | 4 | yes |
| GO:0019430 | removal of superoxide radicals | 2.9126 | 4 | yes |
| GO:0001501 | skeletal system development | 1.9417 | 4 | yes |
| GO:0002228 | natural killer cell mediated immunity | 1.9417 | 4 | yes |
| GO:0030101 | natural killer cell activation | 1.9417 | 4 | yes |
| GO:0042267 | natural killer cell mediated cytotoxicity | 1.9417 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PRDX1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 3.8835 | 3 | no |
| DOID:0050686 | organ system cancer | 2.9126 | 3 | no |
| DOID:1289 | neurodegenerative disease | 2.9126 | 4 | no |
| DOID:0050700 | cardiomyopathy | 1.9417 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.9417 | 5 | no |
| DOID:114 | heart disease | 1.9417 | 3 | no |
| DOID:2843 | long QT syndrome | 1.9417 | 6 | no |
| DOID:0111962 | combined immunodeficiency | 1.9417 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.9417 | 3 | no |
| DOID:0050890 | synucleinopathy | 1.9417 | 5 | no |
| DOID:0060894 | early-onset Parkinsons disease | 1.9417 | 7 | no |
| DOID:14330 | Parkinsons disease | 1.9417 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| THIO_HUMAN | [view interactions] | Low throughput | no | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| TCTP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRXN1_HUMAN | [view interactions] | Low throughput | no | no |
| MOB1A_HUMAN | [view interactions] | Low throughput | no | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HMN1_HUMAN | [view interactions] | Low throughput | no | no |
| SESN2_HUMAN | [view interactions] | Low throughput | no | no |
| SESN1_HUMAN | [view interactions] | Low throughput | no | no |
| UCHL5_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE3A_HUMAN | [view interactions] | Low throughput | no | yes |
| TRIM4_HUMAN | [view interactions] | Low throughput | no | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
| PRDX4_HUMAN | [view interactions] | Low throughput | no | yes |
| STK4_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE2F_HUMAN | [view interactions] | Low throughput | no | yes |
| RBX2_HUMAN | [view interactions] | Low throughput | no | yes |
| MK14_HUMAN | [view interactions] | Low throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STK3_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK1_HUMAN | [view interactions] | Low throughput | no | no |
| CDC26_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSNAX_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC15_HUMAN | [view interactions] | High throughput | no | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH3_HUMAN | [view interactions] | High throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNB1_HUMAN | [view interactions] | High throughput | no | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADX_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMYM1_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAD51_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EM55_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| URP2_HUMAN | [view interactions] | High throughput | no | no |
| URM1_HUMAN | [view interactions] | High throughput | no | yes |
| FL2D_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIPRL_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| DNPH1_HUMAN | [view interactions] | High throughput | no | yes |
| LRSM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFR_HUMAN | [view interactions] | High throughput | no | yes |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| CO1A1_HUMAN | [view interactions] | High throughput | no | yes |
| TRMB_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| MSH6_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAX_HUMAN | [view interactions] | High throughput | no | yes |
| DAB2_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOSB1_HUMAN | [view interactions] | High throughput | no | yes |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| NCF1_HUMAN | [view interactions] | High throughput | no | no |
| TNG2_HUMAN | [view interactions] | High throughput | no | yes |
| ERI1_HUMAN | [view interactions] | High throughput | no | yes |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HTRA3_HUMAN | [view interactions] | High throughput | no | no |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HBA_HUMAN | [view interactions] | High throughput | no | no |
| PDP1_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX17_HUMAN | [view interactions] | High throughput | no | yes |
| RNLS_HUMAN | [view interactions] | High throughput | no | no |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| ADHX_HUMAN | [view interactions] | High throughput | no | yes |
| MYD88_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| SH21B_HUMAN | [view interactions] | High throughput | no | no |
| AXIN2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGB6_HUMAN | [view interactions] | High throughput | no | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNB2_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCR4_HUMAN | [view interactions] | High throughput | no | yes |
| PE2R4_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK3_HUMAN | [view interactions] | High throughput | no | no |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
| CSN6_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| CSAG2_HUMAN | [view interactions] | High throughput | no | no |
| IRF3_HUMAN | [view interactions] | High throughput | no | yes |
| LSM5_HUMAN | [view interactions] | High throughput | no | no |
| PIDD1_HUMAN | [view interactions] | High throughput | no | yes |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGN_HUMAN | [view interactions] | High throughput | no | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| TIPIN_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| TXND5_HUMAN | [view interactions] | High throughput | no | yes |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| SKI_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| DC4L2_HUMAN | [view interactions] | High throughput | no | no |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGF11_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| R144A_HUMAN | [view interactions] | High throughput | no | yes |
| TISD_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| TET2_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| VRK3_HUMAN | [view interactions] | High throughput | no | yes |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| CTBP2_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| CMTR1_HUMAN | [view interactions] | High throughput | no | yes |
| ARI2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| AL3A1_HUMAN | [view interactions] | High throughput | no | no |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| PPR21_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4G_HUMAN | [view interactions] | High throughput | no | no |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| LUC7L_HUMAN | [view interactions] | High throughput | no | yes |
| TRI26_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAB_HUMAN | [view interactions] | High throughput | no | yes |
| ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PIGR_HUMAN | [view interactions] | High throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX43_HUMAN | [view interactions] | High throughput | no | no |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| GRAM4_HUMAN | [view interactions] | High throughput | no | no |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| CDC20_HUMAN | [view interactions] | High throughput | no | no |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| DJC21_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| MED11_HUMAN | [view interactions] | High throughput | no | no |
| MED19_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| MED25_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED31_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| P63_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR1_HUMAN | [view interactions] | Computational | no | yes |
| TLR4_HUMAN | [view interactions] | Computational | no | yes |
| GSHR_HUMAN | [view interactions] | Computational | no | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| M3K5_HUMAN | [view interactions] | Computational | no | yes |
| THIOM_HUMAN | [view interactions] | Computational | no | yes |
| CP2E1_HUMAN | [view interactions] | Computational | no | no |
| GDPD5_HUMAN | [view interactions] | Computational | no | no |
| CDK5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |