Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CATA_HUMAN

GO
G2C
SynGO

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI000007 TRG_PTS1 TRG 524 527 -

Molecular function

Term Name % Distance from the top of the tree Annotated in CATA_HUMAN
GO:0046872 metal ion binding 29.7297 4 yes
GO:0042803 protein homodimerization activity 17.5676 4 yes
GO:0020037 heme binding 5.4054 4 yes
GO:0050661 NADP binding 4.0541 4 yes
GO:0000268 peroxisome targeting sequence binding 2.7027 5 yes
GO:0004046 aminoacylase activity 2.7027 5 yes
GO:0005048 signal sequence binding 2.7027 4 yes
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2.7027 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CATA_HUMAN
GO:0031323 regulation of cellular metabolic process 44.5946 4 yes
GO:0048523 negative regulation of cellular process 44.5946 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 44.5946 4 yes
GO:0060255 regulation of macromolecule metabolic process 44.5946 4 yes
GO:0080090 regulation of primary metabolic process 44.5946 4 yes
GO:0048522 positive regulation of cellular process 43.2432 4 yes
GO:0010646 regulation of cell communication 36.4865 4 yes
GO:0009893 positive regulation of metabolic process 36.4865 4 no
GO:0009966 regulation of signal transduction 35.1351 4 yes
GO:0010468 regulation of gene expression 33.7838 5 yes
GO:0043436 oxoacid metabolic process 32.4324 4 no
GO:0009889 regulation of biosynthetic process 31.0811 4 yes
GO:0031326 regulation of cellular biosynthetic process 31.0811 5 yes
GO:0019752 carboxylic acid metabolic process 31.0811 5 no
GO:0010556 regulation of macromolecule biosynthetic process 29.7297 5 yes
GO:0010941 regulation of cell death 29.7297 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 29.7297 5 yes
GO:0043067 regulation of programmed cell death 29.7297 5 yes
GO:1902531 regulation of intracellular signal transduction 29.7297 5 yes
GO:0006796 phosphate-containing compound metabolic process 29.7297 4 no
GO:0051252 regulation of RNA metabolic process 28.3784 5 yes
GO:0051128 regulation of cellular component organization 28.3784 4 no
GO:0031325 positive regulation of cellular metabolic process 28.3784 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 28.3784 5 no
GO:0006355 regulation of DNA-templated transcription 27.0270 6 yes
GO:0042981 regulation of apoptotic process 27.0270 6 yes
GO:1903506 regulation of nucleic acid-templated transcription 27.0270 7 yes
GO:2001141 regulation of RNA biosynthetic process 27.0270 6 yes
GO:0032787 monocarboxylic acid metabolic process 27.0270 6 no
GO:0051246 regulation of protein metabolic process 27.0270 5 no
GO:0010604 positive regulation of macromolecule metabolic process 27.0270 5 no
GO:0071310 cellular response to organic substance 25.6757 4 yes
GO:0006996 organelle organization 25.6757 4 no
GO:0010648 negative regulation of cell communication 25.6757 5 no
GO:0023057 negative regulation of signaling 25.6757 4 no
GO:0060548 negative regulation of cell death 24.3243 5 yes
GO:0009892 negative regulation of metabolic process 24.3243 4 no
GO:0010605 negative regulation of macromolecule metabolic process 24.3243 5 no
GO:0048585 negative regulation of response to stimulus 24.3243 4 no
GO:0051240 positive regulation of multicellular organismal process 24.3243 4 no
GO:0043069 negative regulation of programmed cell death 22.9730 6 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 22.9730 5 no
GO:0009968 negative regulation of signal transduction 22.9730 5 no
GO:0080134 regulation of response to stress 22.9730 4 no
GO:0022607 cellular component assembly 22.9730 4 no
GO:0033993 response to lipid 21.6216 4 yes
GO:0043066 negative regulation of apoptotic process 21.6216 7 yes
GO:0031324 negative regulation of cellular metabolic process 21.6216 5 no
GO:0051049 regulation of transport 21.6216 4 no
GO:0048584 positive regulation of response to stimulus 20.2703 4 yes
GO:0045595 regulation of cell differentiation 20.2703 4 no
GO:1901701 cellular response to oxygen-containing compound 20.2703 4 no
GO:0009967 positive regulation of signal transduction 18.9189 5 yes
GO:0010243 response to organonitrogen compound 18.9189 4 yes
GO:0010647 positive regulation of cell communication 18.9189 5 yes
GO:0014070 response to organic cyclic compound 18.9189 4 yes
GO:0023056 positive regulation of signaling 18.9189 4 yes
GO:0031667 response to nutrient levels 14.8649 4 yes
GO:0008202 steroid metabolic process 13.5135 4 yes
GO:1902533 positive regulation of intracellular signal transduction 13.5135 6 yes
GO:0042743 hydrogen peroxide metabolic process 12.1622 4 yes
GO:0097305 response to alcohol 12.1622 4 yes
GO:1901652 response to peptide 12.1622 4 yes
GO:0000302 response to reactive oxygen species 10.8108 4 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 10.8108 4 yes
GO:0070848 response to growth factor 10.8108 4 yes
GO:0071363 cellular response to growth factor stimulus 10.8108 5 yes
GO:0042744 hydrogen peroxide catabolic process 9.4595 4 yes
GO:0046486 glycerolipid metabolic process 9.4595 4 yes
GO:0010038 response to metal ion 8.1081 4 yes
GO:0015980 energy derivation by oxidation of organic compounds 8.1081 4 yes
GO:0032355 response to estradiol 8.1081 4 yes
GO:0036293 response to decreased oxygen levels 8.1081 4 yes
GO:0042542 response to hydrogen peroxide 8.1081 4 yes
GO:0043434 response to peptide hormone 8.1081 4 yes
GO:1902652 secondary alcohol metabolic process 8.1081 4 yes
GO:0001649 osteoblast differentiation 6.7568 4 yes
GO:0008203 cholesterol metabolic process 6.7568 5 yes
GO:0009416 response to light stimulus 6.7568 4 yes
GO:0016125 sterol metabolic process 6.7568 4 yes
GO:0045471 response to ethanol 6.7568 5 yes
GO:0006638 neutral lipid metabolic process 5.4054 4 yes
GO:0006639 acylglycerol metabolic process 5.4054 5 yes
GO:0006641 triglyceride metabolic process 5.4054 6 yes
GO:0009411 response to UV 5.4054 5 yes
GO:0009743 response to carbohydrate 5.4054 4 yes
GO:0032088 negative regulation of NF-kappaB transcription factor activity 5.4054 5 yes
GO:0032868 response to insulin 5.4054 5 yes
GO:0033273 response to vitamin 5.4054 4 yes
GO:0034284 response to monosaccharide 5.4054 5 yes
GO:0043433 negative regulation of DNA-binding transcription factor activity 5.4054 4 yes
GO:0046686 response to cadmium ion 5.4054 5 yes
GO:0009060 aerobic respiration 4.0541 6 yes
GO:0009650 UV protection 4.0541 6 yes
GO:0010288 response to lead ion 4.0541 5 yes
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 4.0541 6 yes
GO:0033591 response to L-ascorbic acid 4.0541 5 yes
GO:0036296 response to increased oxygen levels 4.0541 4 yes
GO:0045333 cellular respiration 4.0541 5 yes
GO:0051092 positive regulation of NF-kappaB transcription factor activity 4.0541 5 yes
GO:0060429 epithelium development 4.0541 4 yes
GO:0070542 response to fatty acid 4.0541 4 yes
GO:0001657 ureteric bud development 2.7027 5 yes
GO:0009642 response to light intensity 2.7027 5 yes
GO:0010193 response to ozone 2.7027 4 yes
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 2.7027 7 yes
GO:0020027 hemoglobin metabolic process 2.7027 4 yes
GO:0033189 response to vitamin A 2.7027 5 yes
GO:0033197 response to vitamin E 2.7027 4 yes
GO:0051302 regulation of cell division 2.7027 4 yes
GO:0051781 positive regulation of cell division 2.7027 5 yes
GO:0061692 cellular detoxification of hydrogen peroxide 2.7027 4 yes
GO:0072073 kidney epithelium development 2.7027 5 yes
GO:0072163 mesonephric epithelium development 2.7027 6 yes
GO:0072164 mesonephric tubule development 2.7027 4 yes
GO:0080184 response to phenylpropanoid 2.7027 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in CATA_HUMAN
DOID:0050686 organ system cancer 2.7027 3 no
DOID:6457 Cowden syndrome 2.7027 3 no
DOID:0080000 muscular disease 2.7027 3 no
DOID:423 myopathy 2.7027 5 no
DOID:66 muscle tissue disease 2.7027 4 no
DOID:9884 muscular dystrophy 2.7027 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CATA_HUMAN [view entry] [view interactions] Low throughput yes no
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
TYSD1_HUMAN [view interactions] Low throughput no yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB18_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB6A_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB14_HUMAN [view entry] [view interactions] Low throughput yes yes
FAS_HUMAN [view entry] [view interactions] Low throughput yes no
LACC1_HUMAN [view interactions] Low throughput no yes
ECHP_HUMAN [view interactions] Low throughput no no
PEX5_HUMAN [view interactions] Low throughput no yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
ABL2_HUMAN [view entry] [view interactions] Low throughput yes yes
PD1L1_HUMAN [view interactions] High throughput no no
DX39B_HUMAN [view interactions] High throughput no no
NALP7_HUMAN [view interactions] High throughput no no
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
ITA2B_HUMAN [view interactions] High throughput no no
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
STIM1_HUMAN [view interactions] High throughput no yes
MECP2_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
GDE_HUMAN [view entry] [view interactions] High throughput yes no
AL7A1_HUMAN [view entry] [view interactions] High throughput yes no
ATIF1_HUMAN [view interactions] High throughput no yes
BCAT2_HUMAN [view interactions] High throughput no no
COF1_HUMAN [view entry] [view interactions] High throughput yes no
COF2_HUMAN [view entry] [view interactions] High throughput yes yes
ENOB_HUMAN [view entry] [view interactions] High throughput yes no
CH10_HUMAN [view interactions] High throughput no yes
LDHA_HUMAN [view entry] [view interactions] High throughput yes yes
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
PGM1_HUMAN [view interactions] High throughput no no
IPYR2_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
SODM_HUMAN [view entry] [view interactions] High throughput yes no
DHSO_HUMAN [view interactions] High throughput no no
UFC1_HUMAN [view interactions] High throughput no yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
FAHD1_HUMAN [view interactions] High throughput no yes
FAH2A_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX5_HUMAN [view entry] [view interactions] High throughput yes yes
TNG2_HUMAN [view interactions] High throughput no yes
UTRN_HUMAN [view entry] [view interactions] High throughput yes yes
PERM_HUMAN [view entry] [view interactions] High throughput yes no
ACSL6_HUMAN [view entry] [view interactions] High throughput yes yes
CPT2_HUMAN [view entry] [view interactions] High throughput yes yes
GATB_HUMAN [view interactions] High throughput no yes
ACSL1_HUMAN [view interactions] High throughput no no
PEX7_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
KEAP1_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
UBP53_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
MIS12_HUMAN [view interactions] High throughput no yes
SMCA4_HUMAN [view interactions] High throughput no yes
GNAS1_HUMAN [view entry] [view interactions] High throughput yes yes
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
MET14_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
SH2D3_HUMAN [view interactions] High throughput no no
ITSN1_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
NTM2F_HUMAN [view interactions] High throughput no no
DAG1_HUMAN [view entry] [view interactions] High throughput yes no
SOST_HUMAN [view interactions] High throughput no no
LIMA1_HUMAN [view entry] [view interactions] High throughput yes no
GBG12_HUMAN [view entry] [view interactions] High throughput yes yes
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
DHB4_HUMAN [view entry] [view interactions] High throughput yes yes
POTEJ_HUMAN [view interactions] High throughput no no
MYO1B_HUMAN [view entry] [view interactions] High throughput yes no
NUD19_HUMAN [view interactions] High throughput no no
LONP2_HUMAN [view interactions] High throughput no yes
ACOX1_HUMAN [view interactions] High throughput no yes
ADAS_HUMAN [view interactions] High throughput no yes
PEAK1_HUMAN [view interactions] High throughput no yes
DMD_HUMAN [view entry] [view interactions] High throughput yes no
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC4_HUMAN [view interactions] High throughput no yes
HDAC5_HUMAN [view interactions] High throughput no yes
ASF1A_HUMAN [view interactions] High throughput no no
NFKB1_HUMAN [view interactions] High throughput no yes
PF21B_HUMAN [view interactions] High throughput no no
AMY1B_HUMAN [view interactions] High throughput no no
AMY2B_HUMAN [view interactions] High throughput no no
AMYP_HUMAN [view interactions] High throughput no no
PCNA_HUMAN [view interactions] High throughput no no
GRPE1_HUMAN [view interactions] High throughput no yes
DHX40_HUMAN [view interactions] High throughput no yes
ECH1_HUMAN [view interactions] High throughput no yes
GSTK1_HUMAN [view entry] [view interactions] High throughput yes yes
OCTC_HUMAN [view interactions] High throughput no yes
HACL1_HUMAN [view interactions] High throughput no no
DECR2_HUMAN [view entry] [view interactions] High throughput yes no
PLPL8_HUMAN [view interactions] High throughput no yes
PECR_HUMAN [view interactions] High throughput no yes
DHRS4_HUMAN [view entry] [view interactions] High throughput yes no
NUD12_HUMAN [view interactions] High throughput no yes
ISOC1_HUMAN [view interactions] High throughput no no
PTGR3_HUMAN [view interactions] High throughput no yes
ACD11_HUMAN [view interactions] High throughput no yes
HSDL2_HUMAN [view entry] [view interactions] High throughput yes yes
HMGCL_HUMAN [view interactions] High throughput no yes
HYES_HUMAN [view interactions] High throughput no no
SCP2_HUMAN [view interactions] High throughput no no
G6PD_HUMAN [view entry] [view interactions] High throughput yes no
THIK_HUMAN [view entry] [view interactions] High throughput yes yes
ECI2_HUMAN [view entry] [view interactions] High throughput yes yes
PEX14_HUMAN [view interactions] High throughput no yes
ACOX3_HUMAN [view interactions] High throughput no yes
GNPAT_HUMAN [view entry] [view interactions] High throughput yes no
PAHX_HUMAN [view interactions] High throughput no yes
ACOT8_HUMAN [view entry] [view interactions] High throughput yes yes
VWA8_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
SNX5_HUMAN [view entry] [view interactions] High throughput yes yes
SNX6_HUMAN [view entry] [view interactions] High throughput yes no
TBC19_HUMAN [view interactions] High throughput no yes
K1841_HUMAN [view interactions] High throughput no yes
DPOD1_HUMAN [view interactions] High throughput no yes
5NTD_HUMAN [view entry] [view interactions] High throughput yes yes
FETUA_HUMAN [view interactions] High throughput no no
NDK8_HUMAN [view interactions] High throughput no no
ORC4_HUMAN [view interactions] High throughput no yes
PSD12_HUMAN [view interactions] High throughput no yes
SCML2_HUMAN [view interactions] High throughput no no
YETS2_HUMAN [view interactions] High throughput no no
ORC3_HUMAN [view interactions] High throughput no yes
CK049_HUMAN [view interactions] High throughput no yes
KAISO_HUMAN [view interactions] High throughput no yes
ZCHC8_HUMAN [view interactions] High throughput no yes
MTA1_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view interactions] High throughput no yes
FHI2A_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
RD23B_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
CCDC8_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
WDTC1_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
ZUP1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
REST_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CATB_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
NEK2_HUMAN [view interactions] High throughput no no
BRCA2_HUMAN [view interactions] High throughput no no
HDAC2_HUMAN [view interactions] High throughput no yes
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
DYR1A_HUMAN [view interactions] High throughput no yes
RBP56_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CIC_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
XP32_HUMAN [view interactions] High throughput no no
FA20C_HUMAN [view interactions] High throughput no no
GPX8_HUMAN [view interactions] Computational no no
TRXR1_HUMAN [view interactions] Computational no yes
AATM_HUMAN [view entry] [view interactions] Computational yes yes
S27A2_HUMAN [view interactions] Computational no no
ALDH2_HUMAN [view entry] [view interactions] Computational yes no
DCMC_HUMAN [view interactions] Computational no no
KYNU_HUMAN [view interactions] Computational no no
AKT1_HUMAN [view entry] [view interactions] Computational yes yes
ACOX2_HUMAN [view interactions] Computational no yes
PRDX3_HUMAN [view interactions] Computational no yes
HMOX1_HUMAN [view interactions] Computational no no
HPGDS_HUMAN [view interactions] Computational no no
INS_HUMAN [view interactions] Computational no no
GSHR_HUMAN [view interactions] Computational no yes
HAOX2_HUMAN [view interactions] Computational no no
GPX5_HUMAN [view interactions] Computational no no
TALDO_HUMAN [view entry] [view interactions] Computational yes no
NF2L2_HUMAN [view interactions] Computational no yes
TPIS_HUMAN [view entry] [view interactions] Computational yes yes
NOS2_HUMAN [view interactions] Computational no yes
PRDX6_HUMAN [view entry] [view interactions] Computational yes yes
ACOT4_HUMAN [view interactions] Computational no yes
ACOT2_HUMAN [view interactions] Computational no yes
BAAT_HUMAN [view interactions] Computational no no
3HAO_HUMAN [view interactions] Computational no no
GPX2_HUMAN [view interactions] Computational no no
FOXO1_HUMAN [view interactions] Computational no yes
AMACR_HUMAN [view interactions] Computational no yes
SODE_HUMAN [view interactions] Computational no yes
GPX3_HUMAN [view interactions] Computational no no
GPX1_HUMAN [view entry] [view interactions] Computational yes yes
MPV17_HUMAN [view interactions] Computational no no
NUDT7_HUMAN [view interactions] Computational no yes
FUMH_HUMAN [view entry] [view interactions] Computational yes yes
THIO_HUMAN [view interactions] Computational no yes
IDE_HUMAN [view interactions] Computational no yes
SPYA_HUMAN [view interactions] Computational no no
HAOX1_HUMAN [view interactions] Computational no no
ALAT1_HUMAN [view interactions] Computational no no
OXDA_HUMAN [view interactions] Computational no no
SRXN1_HUMAN [view interactions] Computational no no
FOXO3_HUMAN [view interactions] Computational no yes
CACP_HUMAN [view entry] [view interactions] Computational yes yes
GPX6_HUMAN [view interactions] Computational no no
GRB2_HUMAN [view entry] [view interactions] Computational yes yes
PAOX_HUMAN [view interactions] Computational no no
GPX4_HUMAN [view entry] [view interactions] Computational yes no
IDHC_HUMAN [view interactions] Computational no no
AL3A2_HUMAN [view entry] [view interactions] Computational yes yes
ALBU_HUMAN [view interactions] Computational no no
GPX7_HUMAN [view interactions] Computational no no
OXDD_HUMAN [view interactions] Computational no yes
ACON_HUMAN [view entry] [view interactions] Computational yes yes
SOX_HUMAN [view interactions] Computational no no
PEX13_HUMAN [view interactions] Computational no yes