Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HCD2_HUMAN

In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5-ends (PubMed, PubMed, PubMed, PubMed, PubMed). Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity (PubMed, PubMed). The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit (PubMed, PubMed, PubMed). The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme (PubMed). Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in HCD2_HUMAN
GO:0003723 RNA binding 27.5676 4 yes
GO:0017076 purine nucleotide binding 24.3243 4 no
GO:0032555 purine ribonucleotide binding 24.3243 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.7027 4 no
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5.9459 4 yes
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity 2.7027 5 yes
GO:0000049 tRNA binding 1.6216 5 yes
GO:0004303 estradiol 17-beta-dehydrogenase activity 1.0811 5 yes
GO:0008709 cholate 7-alpha-dehydrogenase activity 1.0811 5 yes
GO:0030283 testosterone dehydrogenase [NAD(P)] activity 1.0811 5 yes
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.0811 4 yes
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 1.0811 6 yes
GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 1.0811 5 yes
GO:0047035 testosterone dehydrogenase (NAD+) activity 1.0811 6 yes
GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity 1.0811 5 yes
GO:0106281 chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity 1.0811 5 yes
GO:0106282 isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1.0811 5 yes
GO:0106283 ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1.0811 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in HCD2_HUMAN
GO:0048522 positive regulation of cellular process 42.1622 4 no
GO:0060255 regulation of macromolecule metabolic process 37.2973 4 no
GO:0080090 regulation of primary metabolic process 36.7568 4 no
GO:0051171 regulation of nitrogen compound metabolic process 36.2162 4 no
GO:0031323 regulation of cellular metabolic process 35.1351 4 no
GO:0048523 negative regulation of cellular process 33.5135 4 no
GO:0022607 cellular component assembly 29.7297 4 yes
GO:0009893 positive regulation of metabolic process 28.6486 4 no
GO:0006996 organelle organization 28.1081 4 yes
GO:0019752 carboxylic acid metabolic process 28.1081 5 yes
GO:0043436 oxoacid metabolic process 28.1081 4 yes
GO:0010468 regulation of gene expression 28.1081 5 no
GO:0010646 regulation of cell communication 26.4865 4 no
GO:0051128 regulation of cellular component organization 25.9459 4 no
GO:0010604 positive regulation of macromolecule metabolic process 24.3243 5 no
GO:0009889 regulation of biosynthetic process 23.7838 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.7838 5 no
GO:0051246 regulation of protein metabolic process 23.7838 5 no
GO:0031326 regulation of cellular biosynthetic process 23.2432 5 no
GO:0009966 regulation of signal transduction 23.2432 4 no
GO:0010556 regulation of macromolecule biosynthetic process 22.7027 5 no
GO:0006796 phosphate-containing compound metabolic process 22.7027 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 22.1622 5 no
GO:0032787 monocarboxylic acid metabolic process 21.0811 6 yes
GO:0010941 regulation of cell death 21.0811 4 no
GO:0031325 positive regulation of cellular metabolic process 20.5405 5 no
GO:0043412 macromolecule modification 17.2973 4 yes
GO:0043933 protein-containing complex organization 16.7568 4 yes
GO:0065003 protein-containing complex assembly 16.2162 5 yes
GO:0090304 nucleic acid metabolic process 12.9730 4 yes
GO:1901565 organonitrogen compound catabolic process 11.3514 4 yes
GO:0016054 organic acid catabolic process 10.8108 4 yes
GO:0046395 carboxylic acid catabolic process 10.8108 5 yes
GO:0006631 fatty acid metabolic process 9.7297 4 yes
GO:1901362 organic cyclic compound biosynthetic process 8.6486 4 yes
GO:0016070 RNA metabolic process 8.1081 5 yes
GO:0016042 lipid catabolic process 7.5676 4 yes
GO:0006396 RNA processing 7.0270 6 yes
GO:0009063 cellular amino acid catabolic process 7.0270 4 yes
GO:0044242 cellular lipid catabolic process 7.0270 4 yes
GO:0007005 mitochondrion organization 6.4865 5 yes
GO:0009062 fatty acid catabolic process 6.4865 5 yes
GO:0030258 lipid modification 6.4865 4 yes
GO:0072329 monocarboxylic acid catabolic process 6.4865 6 yes
GO:0006635 fatty acid beta-oxidation 5.9459 6 yes
GO:0016053 organic acid biosynthetic process 5.9459 4 yes
GO:0019395 fatty acid oxidation 5.9459 5 yes
GO:0034440 lipid oxidation 5.9459 5 yes
GO:0046394 carboxylic acid biosynthetic process 5.9459 5 yes
GO:0008610 lipid biosynthetic process 5.4054 4 yes
GO:1901605 alpha-amino acid metabolic process 5.4054 4 yes
GO:1901606 alpha-amino acid catabolic process 5.4054 5 yes
GO:0051259 protein complex oligomerization 4.8649 6 yes
GO:0009081 branched-chain amino acid metabolic process 4.3243 4 yes
GO:0009083 branched-chain amino acid catabolic process 4.3243 5 yes
GO:0034470 ncRNA processing 4.3243 7 yes
GO:0034660 ncRNA metabolic process 4.3243 6 yes
GO:0051260 protein homooligomerization 4.3243 7 yes
GO:0072330 monocarboxylic acid biosynthetic process 4.3243 6 yes
GO:0008202 steroid metabolic process 3.2432 4 yes
GO:0051262 protein tetramerization 2.7027 7 yes
GO:0006399 tRNA metabolic process 2.1622 7 yes
GO:0031123 RNA 3-end processing 2.1622 7 yes
GO:0051289 protein homotetramerization 2.1622 8 yes
GO:1901617 organic hydroxy compound biosynthetic process 2.1622 4 yes
GO:0000959 mitochondrial RNA metabolic process 1.6216 6 yes
GO:0000966 RNA 5-end processing 1.6216 7 yes
GO:0006549 isoleucine metabolic process 1.6216 5 yes
GO:0006550 isoleucine catabolic process 1.6216 6 yes
GO:0008033 tRNA processing 1.6216 8 yes
GO:0008206 bile acid metabolic process 1.6216 4 yes
GO:0099116 tRNA 5-end processing 1.6216 8 yes
GO:0000963 mitochondrial RNA processing 1.0811 6 yes
GO:0000964 mitochondrial RNA 5-end processing 1.0811 7 yes
GO:0000965 mitochondrial RNA 3-end processing 1.0811 7 yes
GO:0001510 RNA methylation 1.0811 4 yes
GO:0006400 tRNA modification 1.0811 6 yes
GO:0006694 steroid biosynthetic process 1.0811 5 yes
GO:0006699 bile acid biosynthetic process 1.0811 5 yes
GO:0008207 C21-steroid hormone metabolic process 1.0811 4 yes
GO:0008209 androgen metabolic process 1.0811 4 yes
GO:0008210 estrogen metabolic process 1.0811 4 yes
GO:0009451 RNA modification 1.0811 5 yes
GO:0010467 gene expression 1.0811 4 yes
GO:0030488 tRNA methylation 1.0811 5 yes
GO:0042780 tRNA 3-end processing 1.0811 8 yes
GO:0062173 brexanolone metabolic process 1.0811 4 yes
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process 1.0811 6 yes
GO:0070900 mitochondrial tRNA modification 1.0811 7 yes
GO:0070901 mitochondrial tRNA methylation 1.0811 6 yes
GO:0090646 mitochondrial tRNA processing 1.0811 7 yes
GO:0097745 mitochondrial tRNA 5-end processing 1.0811 8 yes
GO:0140053 mitochondrial gene expression 1.0811 5 yes
GO:1900864 mitochondrial RNA modification 1.0811 6 yes
GO:1990180 mitochondrial tRNA 3-end processing 1.0811 8 yes

Disease

Term Name % Distance from top the of the tree Annotated in HCD2_HUMAN
DOID:1289 neurodegenerative disease 1.6216 4 no
DOID:331 central nervous system disease 1.6216 3 no
DOID:700 mitochondrial metabolism disease 1.6216 3 no
DOID:0050155 sensory system disease 1.0811 3 no
DOID:574 peripheral nervous system disease 1.0811 3 no
DOID:870 neuropathy 1.0811 4 no
DOID:0060286 combined oxidative phosphorylation deficiency 1.0811 4 no
DOID:0050890 synucleinopathy 1.0811 5 no
DOID:0060894 early-onset Parkinsons disease 1.0811 7 no
DOID:14330 Parkinsons disease 1.0811 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PINK1_HUMAN [view interactions] Low throughput no yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
HTRA2_HUMAN [view interactions] Low throughput no yes
TOM20_HUMAN [view entry] [view interactions] Low throughput yes yes
TOM40_HUMAN [view interactions] Low throughput no yes
TOM22_HUMAN [view interactions] Low throughput no yes
EF2_HUMAN [view entry] [view interactions] Low throughput yes yes
SUMF1_HUMAN [view interactions] Low throughput no yes
MRPP3_HUMAN [view interactions] Low throughput no yes
HCD2_HUMAN [view entry] [view interactions] Low throughput yes yes
TM10C_HUMAN [view interactions] Low throughput no yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC1_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
PSMD3_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
RNPS1_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
EF1B_HUMAN [view entry] [view interactions] High throughput yes yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
RPAB3_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM3_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
ANO7_HUMAN [view interactions] High throughput no no
PRP19_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
WWP2_HUMAN [view interactions] High throughput no no
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
TMEDA_HUMAN [view interactions] High throughput no yes
SIR3_HUMAN [view interactions] High throughput no yes
HNRDL_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
RPAB1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
HNRH3_HUMAN [view interactions] High throughput no no
RALY_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
H90B3_HUMAN [view interactions] High throughput no no
RHG36_HUMAN [view interactions] High throughput no yes
SPIN1_HUMAN [view interactions] High throughput no no
ARHGF_HUMAN [view entry] [view interactions] High throughput yes no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
MYO9A_HUMAN [view entry] [view interactions] High throughput yes yes
H2A1D_HUMAN [view interactions] High throughput no yes
STA13_HUMAN [view interactions] High throughput no yes
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
ANLN_HUMAN [view interactions] High throughput no yes
SYK_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
RA1L2_HUMAN [view interactions] High throughput no no
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
CHM4C_HUMAN [view interactions] High throughput no yes
ACTBM_HUMAN [view interactions] High throughput no no
ECT2_HUMAN [view interactions] High throughput no no
THIL_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
SYDC_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
PRS8_HUMAN [view interactions] High throughput no yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
HPRT_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
RBM39_HUMAN [view interactions] High throughput no yes
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
WDR76_HUMAN [view interactions] High throughput no no
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
PO2F1_HUMAN [view interactions] High throughput no yes
PIPNB_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
MOB1B_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
HGB1A_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
LA_HUMAN [view interactions] High throughput no yes
CDK1_HUMAN [view interactions] High throughput no no
FGD5_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
ZN363_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
PRS10_HUMAN [view interactions] High throughput no yes
HERC5_HUMAN [view interactions] High throughput no yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
PRDX3_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SUMO2_HUMAN [view interactions] High throughput no yes
RHOJ_HUMAN [view interactions] High throughput no yes
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
XRCC6_HUMAN [view interactions] High throughput no yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
PDIA6_HUMAN [view entry] [view interactions] High throughput yes yes
RHOH_HUMAN [view interactions] High throughput no yes
MCA3_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
ILF2_HUMAN [view interactions] High throughput no yes
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
NH2L1_HUMAN [view interactions] High throughput no yes
SPRNG_HUMAN [view interactions] High throughput no yes
PSME2_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
PSD11_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
GDIR1_HUMAN [view entry] [view interactions] High throughput yes yes
PTBP1_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD7_HUMAN [view interactions] High throughput no yes
TGDS_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view interactions] High throughput no yes
RUVB2_HUMAN [view interactions] High throughput no yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
NOP10_HUMAN [view interactions] High throughput no yes
ALDR_HUMAN [view interactions] High throughput no no
BAX_HUMAN [view interactions] High throughput no yes
AK1BF_HUMAN [view interactions] High throughput no no
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
ARFG2_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
ARFG3_HUMAN [view entry] [view interactions] High throughput yes no
ML12A_HUMAN [view interactions] High throughput no no
GDIR3_HUMAN [view interactions] High throughput no no
EIF3I_HUMAN [view interactions] High throughput no yes
ARPC3_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
5MP2_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
5MP1_HUMAN [view interactions] High throughput no no
PRDX6_HUMAN [view entry] [view interactions] High throughput yes yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
UB2V1_HUMAN [view entry] [view interactions] High throughput yes no
CALU_HUMAN [view interactions] High throughput no yes
PIMT_HUMAN [view entry] [view interactions] High throughput yes yes
CLIC1_HUMAN [view interactions] High throughput no no
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
FABP5_HUMAN [view entry] [view interactions] High throughput yes no
HBA_HUMAN [view interactions] High throughput no no
FKBP2_HUMAN [view interactions] High throughput no yes
GPX4_HUMAN [view entry] [view interactions] High throughput yes no
H2A1B_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
PURA2_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
AT1B3_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
VATH_HUMAN [view entry] [view interactions] High throughput yes yes
B2L14_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
NCF1_HUMAN [view interactions] High throughput no no
RNZ2_HUMAN [view interactions] High throughput no yes
TF7L2_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
M3K7_HUMAN [view interactions] High throughput no yes
FKB1A_HUMAN [view interactions] High throughput no yes
KSYK_HUMAN [view interactions] High throughput no no
FKB1B_HUMAN [view entry] [view interactions] High throughput yes yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
MOES_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
PDIA1_HUMAN [view interactions] High throughput no yes
PSB1_HUMAN [view interactions] High throughput no yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
RAB8B_HUMAN [view entry] [view interactions] High throughput yes no
CUL1_HUMAN [view interactions] High throughput no yes
RCN1_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
CUL4B_HUMAN [view interactions] High throughput no yes
TPD54_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
INO1_HUMAN [view interactions] High throughput no no
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
MYL6_HUMAN [view entry] [view interactions] High throughput yes no
FAKD3_HUMAN [view interactions] High throughput no yes
PPIB_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
DHPR_HUMAN [view entry] [view interactions] High throughput yes no
PCNA_HUMAN [view interactions] High throughput no no
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
SC31A_HUMAN [view entry] [view interactions] High throughput yes yes
AKIP_HUMAN [view interactions] High throughput no yes
S12A4_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
TAGL3_HUMAN [view entry] [view interactions] High throughput yes yes
PDK1_HUMAN [view interactions] High throughput no yes
TADBP_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
TR61B_HUMAN [view interactions] High throughput no yes
TRIP6_HUMAN [view interactions] High throughput no yes
DDR2_HUMAN [view interactions] High throughput no no
UCHL3_HUMAN [view interactions] High throughput no yes
RET_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
MPPB_HUMAN [view interactions] High throughput no yes
AL3B1_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
ATPA_HUMAN [view interactions] High throughput no yes
MRM1_HUMAN [view interactions] High throughput no no
CPSM_HUMAN [view interactions] High throughput no no
ACAD9_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
ETFD_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
DHE3_HUMAN [view entry] [view interactions] High throughput yes yes
CQ080_HUMAN [view interactions] High throughput no yes
HMGCL_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
HMCS2_HUMAN [view interactions] High throughput no no
GAL3A_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3B_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
MRES1_HUMAN [view interactions] High throughput no yes
ODPX_HUMAN [view entry] [view interactions] High throughput yes yes
EFGM_HUMAN [view interactions] High throughput no yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
HINT2_HUMAN [view interactions] High throughput no yes
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
GLNA_HUMAN [view entry] [view interactions] High throughput yes yes
MET17_HUMAN [view interactions] High throughput no yes
MDHC_HUMAN [view entry] [view interactions] High throughput yes yes
RT26_HUMAN [view interactions] High throughput no yes
PYGL_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
CIKS_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
TRAF5_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
CATA_HUMAN [view entry] [view interactions] High throughput yes no
RF1ML_HUMAN [view interactions] High throughput no yes
CUBN_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
RUSD4_HUMAN [view interactions] High throughput no yes
HEM2_HUMAN [view interactions] High throughput no no
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
TACO1_HUMAN [view interactions] High throughput no yes
HDGF_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
TMM70_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
ASB1_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
GRSF1_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
HUWE1_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
DJC15_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
ATG5_HUMAN [view interactions] High throughput no no
CYTC_HUMAN [view entry] [view interactions] High throughput yes yes
SYAM_HUMAN [view interactions] High throughput no yes
ODPAT_HUMAN [view interactions] High throughput no no
COIL_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
A2MG_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
ALDOC_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
PER2_HUMAN [view interactions] High throughput no yes
AL3A1_HUMAN [view interactions] High throughput no no
HROB_HUMAN [view interactions] High throughput no yes
FUMH_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
IDHC_HUMAN [view interactions] High throughput no no
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
KCRM_HUMAN [view interactions] High throughput no no
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV2_HUMAN [view entry] [view interactions] High throughput yes yes
CHD3_HUMAN [view interactions] High throughput no yes
NDUS2_HUMAN [view entry] [view interactions] High throughput yes yes
FAF1_HUMAN [view interactions] High throughput no yes
VATL_HUMAN [view interactions] High throughput no no
UB2D1_HUMAN [view interactions] High throughput no yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
VA0E1_HUMAN [view interactions] High throughput no no
H2AX_HUMAN [view interactions] High throughput no yes
VATF_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
LDHC_HUMAN [view interactions] High throughput no no
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL1_HUMAN [view interactions] High throughput no yes
GSTM1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
GSTA1_HUMAN [view interactions] High throughput no no
ICT1_HUMAN [view interactions] High throughput no yes
GSTA2_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
GSTA5_HUMAN [view interactions] High throughput no no
SIR4_HUMAN [view interactions] High throughput no yes
GSTA3_HUMAN [view interactions] High throughput no no
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
IPYR2_HUMAN [view interactions] High throughput no yes
NAA11_HUMAN [view interactions] High throughput no no
GATM_HUMAN [view interactions] High throughput no no
EIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
OAT_HUMAN [view interactions] High throughput no yes
SRP72_HUMAN [view interactions] High throughput no yes
ACS2A_HUMAN [view interactions] High throughput no no
NOP56_HUMAN [view interactions] High throughput no yes
ACS2B_HUMAN [view interactions] High throughput no no
IGHG2_HUMAN [view interactions] High throughput no no
ACADV_HUMAN [view interactions] High throughput no yes
IGHG1_HUMAN [view interactions] High throughput no no
CPT2_HUMAN [view entry] [view interactions] High throughput yes yes
FL2D_HUMAN [view interactions] High throughput no yes
HCDH_HUMAN [view entry] [view interactions] High throughput yes yes
NEK4_HUMAN [view interactions] High throughput no yes
ACADL_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
ACOX1_HUMAN [view interactions] High throughput no yes
RHG09_HUMAN [view interactions] High throughput no no
ACADM_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
ACD10_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
ACS2L_HUMAN [view interactions] High throughput no yes
TAGL_HUMAN [view interactions] High throughput no no
ECH1_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
ARGI2_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
SUCHY_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
ODB2_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
DHTK1_HUMAN [view interactions] High throughput no no
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
3HIDH_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
HGD_HUMAN [view interactions] High throughput no no
HS905_HUMAN [view interactions] High throughput no no
MCCB_HUMAN [view entry] [view interactions] High throughput yes yes
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
MCCA_HUMAN [view entry] [view interactions] High throughput yes yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
SUOX_HUMAN [view interactions] High throughput no no
DD19A_HUMAN [view interactions] High throughput no yes
PCCA_HUMAN [view entry] [view interactions] High throughput yes yes
CCAR2_HUMAN [view interactions] High throughput no yes
FAAA_HUMAN [view interactions] High throughput no no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
PDC6I_HUMAN [view entry] [view interactions] High throughput yes yes
PGK1_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
PGAM1_HUMAN [view entry] [view interactions] High throughput yes yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
PGAM2_HUMAN [view entry] [view interactions] High throughput yes no
NCBP1_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
PYRG1_HUMAN [view interactions] High throughput no no
SUCB2_HUMAN [view interactions] High throughput no no
HNRL2_HUMAN [view interactions] High throughput no yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
NOP58_HUMAN [view interactions] High throughput no yes
ETFA_HUMAN [view interactions] High throughput no yes
DKC1_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
PI42C_HUMAN [view interactions] High throughput no yes
ACY1_HUMAN [view interactions] High throughput no no
ENOB_HUMAN [view entry] [view interactions] High throughput yes no
ACMSD_HUMAN [view interactions] High throughput no no
PRS6B_HUMAN [view interactions] High throughput no yes
EST3_HUMAN [view interactions] High throughput no yes
CPSF6_HUMAN [view interactions] High throughput no yes
LRP2_HUMAN [view interactions] High throughput no no
ROAA_HUMAN [view interactions] High throughput no yes
LPP60_HUMAN [view interactions] High throughput no yes
PERI_HUMAN [view entry] [view interactions] High throughput yes no
ARLY_HUMAN [view interactions] High throughput no no
ASSY_HUMAN [view interactions] High throughput no yes
ENPLL_HUMAN [view interactions] High throughput no no
GPX1_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD6_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
THOC4_HUMAN [view interactions] High throughput no no
PRDX5_HUMAN [view entry] [view interactions] High throughput yes yes
NAMPT_HUMAN [view interactions] High throughput no no
LDHA_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
BID_HUMAN [view interactions] High throughput no no
ENOG_HUMAN [view entry] [view interactions] High throughput yes yes
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
KPYM_HUMAN [view interactions] High throughput no yes
FEN1_HUMAN [view interactions] High throughput no yes
GSTA4_HUMAN [view interactions] High throughput no yes
SAE2_HUMAN [view interactions] High throughput no yes
GSTM2_HUMAN [view entry] [view interactions] High throughput yes yes
CD2B2_HUMAN [view interactions] High throughput no yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
RBBP7_HUMAN [view interactions] High throughput no yes
GSTM5_HUMAN [view interactions] High throughput no yes
PSME3_HUMAN [view interactions] High throughput no yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
GSTT1_HUMAN [view interactions] High throughput no no
BUB3_HUMAN [view interactions] High throughput no yes
FABPL_HUMAN [view interactions] High throughput no no
MCM4_HUMAN [view interactions] High throughput no yes
HSPB2_HUMAN [view interactions] High throughput no yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB6_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
IVD_HUMAN [view interactions] High throughput no yes
SERPH_HUMAN [view interactions] High throughput no no
MYH4_HUMAN [view interactions] High throughput no no
CSN8_HUMAN [view interactions] High throughput no yes
PUR6_HUMAN [view entry] [view interactions] High throughput yes yes
CH10_HUMAN [view interactions] High throughput no yes
ADH4_HUMAN [view interactions] High throughput no no
RTCB_HUMAN [view interactions] High throughput no yes
NDUA7_HUMAN [view entry] [view interactions] High throughput yes yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
CAH3_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
PYGB_HUMAN [view entry] [view interactions] High throughput yes no
COPE_HUMAN [view interactions] High throughput no yes
THIM_HUMAN [view interactions] High throughput no yes
PLP2_HUMAN [view interactions] High throughput no yes
GSTO1_HUMAN [view entry] [view interactions] High throughput yes yes
METK2_HUMAN [view interactions] High throughput no no
ACADS_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
HMCS1_HUMAN [view interactions] High throughput no yes
BACH_HUMAN [view entry] [view interactions] High throughput yes yes
DUS26_HUMAN [view interactions] High throughput no yes
M4K1_HUMAN [view interactions] High throughput no no
NACAM_HUMAN [view interactions] High throughput no no
VINC_HUMAN [view entry] [view interactions] High throughput yes no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3D_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
PSD12_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
SYAC_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
RMXL2_HUMAN [view interactions] High throughput no no
AAR2_HUMAN [view interactions] High throughput no no
NAA50_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
MYL1_HUMAN [view interactions] High throughput no no
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
PAIRB_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
SF3B6_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
XRCC5_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
CHTOP_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
CPVL_HUMAN [view interactions] High throughput no no
SNAI1_HUMAN [view interactions] High throughput no yes
AGO2_HUMAN [view interactions] Computational no yes
ECHP_HUMAN [view interactions] Computational no no
SODC_HUMAN [view interactions] Computational no yes
POP1_HUMAN [view interactions] Computational no no
DICER_HUMAN [view entry] [view interactions] Computational yes yes
THIK_HUMAN [view entry] [view interactions] Computational yes yes
TRBP2_HUMAN [view interactions] Computational no yes
SCP2_HUMAN [view interactions] Computational no no
RPP14_HUMAN [view interactions] Computational no no
ECHM_HUMAN [view interactions] Computational no yes
RPP30_HUMAN [view interactions] Computational no yes
RPP40_HUMAN [view interactions] Computational no no
RPP25_HUMAN [view interactions] Computational no yes
CLP1_HUMAN [view interactions] Computational no yes
POP5_HUMAN [view interactions] Computational no no
POP7_HUMAN [view interactions] Computational no yes
RPP29_HUMAN [view entry] [view interactions] Computational yes yes
FSIP1_HUMAN [view interactions] Computational no no
THIC_HUMAN [view interactions] Computational no yes
RPP21_HUMAN [view interactions] Computational no no
RPP38_HUMAN [view interactions] Computational no yes