Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HCD2_HUMAN

In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5-ends (PubMed, PubMed, PubMed, PubMed, PubMed). Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity (PubMed, PubMed). The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit (PubMed, PubMed, PubMed). The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme (PubMed). Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in HCD2_HUMAN
GO:0043168 anion binding 32.6531 4 no
GO:0000166 nucleotide binding 31.1224 4 no
GO:0017076 purine nucleotide binding 28.5714 5 no
GO:0003723 RNA binding 27.5510 4 yes
GO:0032555 purine ribonucleotide binding 24.4898 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.9592 4 no
GO:0030554 adenyl nucleotide binding 21.4286 6 no
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5.6122 4 yes
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity 2.5510 5 yes
GO:0000049 tRNA binding 1.5306 5 yes
GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)] activity 1.0204 5 yes
GO:0008709 cholate 7-alpha-dehydrogenase activity 1.0204 5 yes
GO:0030283 testosterone dehydrogenase [NAD(P)] activity 1.0204 5 yes
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.0204 4 yes
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 1.0204 5 yes
GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 1.0204 5 yes
GO:0047035 testosterone dehydrogenase (NAD+) activity 1.0204 6 yes
GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity 1.0204 5 yes
GO:0106281 chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity 1.0204 5 yes
GO:0106282 isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1.0204 5 yes
GO:0106283 ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1.0204 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in HCD2_HUMAN
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0031323 regulation of cellular metabolic process 38.2653 4 no
GO:0060255 regulation of macromolecule metabolic process 38.2653 4 no
GO:0080090 regulation of primary metabolic process 37.2449 4 no
GO:0048523 negative regulation of cellular process 32.1429 4 no
GO:0009889 regulation of biosynthetic process 31.6327 4 no
GO:0031326 regulation of cellular biosynthetic process 31.6327 5 no
GO:0010556 regulation of macromolecule biosynthetic process 31.1224 5 no
GO:0009893 positive regulation of metabolic process 30.6122 4 no
GO:0022607 cellular component assembly 29.5918 4 yes
GO:0010468 regulation of gene expression 29.0816 6 no
GO:0006996 organelle organization 28.5714 4 yes
GO:0010646 regulation of cell communication 27.5510 4 no
GO:0006796 phosphate-containing compound metabolic process 26.5306 4 no
GO:0010604 positive regulation of macromolecule metabolic process 26.5306 5 no
GO:0043436 oxoacid metabolic process 26.5306 4 yes
GO:0019752 carboxylic acid metabolic process 26.0204 5 yes
GO:0051128 regulation of cellular component organization 25.5102 4 no
GO:0051246 regulation of protein metabolic process 25.5102 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0009966 regulation of signal transduction 23.9796 4 no
GO:0031325 positive regulation of cellular metabolic process 23.9796 5 no
GO:0009891 positive regulation of biosynthetic process 20.9184 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.4082 6 no
GO:0031328 positive regulation of cellular biosynthetic process 20.4082 6 no
GO:0032787 monocarboxylic acid metabolic process 19.8980 6 yes
GO:1901565 organonitrogen compound catabolic process 18.3673 4 yes
GO:0043933 protein-containing complex organization 16.8367 4 yes
GO:0043412 macromolecule modification 16.3265 4 yes
GO:0065003 protein-containing complex assembly 14.7959 5 yes
GO:0090304 nucleic acid metabolic process 14.2857 4 yes
GO:1901362 organic cyclic compound biosynthetic process 11.7347 4 yes
GO:0009059 macromolecule biosynthetic process 10.7143 4 yes
GO:0016054 organic acid catabolic process 9.6939 4 yes
GO:0016070 RNA metabolic process 9.6939 5 yes
GO:0046395 carboxylic acid catabolic process 9.6939 5 yes
GO:0006631 fatty acid metabolic process 9.1837 4 yes
GO:0007005 mitochondrion organization 7.6531 5 yes
GO:0009063 amino acid catabolic process 6.6327 4 yes
GO:0016042 lipid catabolic process 6.6327 4 yes
GO:0044242 cellular lipid catabolic process 6.1224 4 yes
GO:0072329 monocarboxylic acid catabolic process 5.6122 6 yes
GO:0008610 lipid biosynthetic process 5.6122 4 yes
GO:0009062 fatty acid catabolic process 5.6122 5 yes
GO:0016053 organic acid biosynthetic process 5.6122 4 yes
GO:0030258 lipid modification 5.6122 4 yes
GO:0046394 carboxylic acid biosynthetic process 5.6122 5 yes
GO:0141188 nucleic acid catabolic process 5.1020 5 yes
GO:1901605 alpha-amino acid metabolic process 5.1020 4 yes
GO:1901606 alpha-amino acid catabolic process 5.1020 5 yes
GO:0006396 RNA processing 5.1020 6 yes
GO:0006635 fatty acid beta-oxidation 5.1020 6 yes
GO:0019395 fatty acid oxidation 5.1020 5 yes
GO:0034440 lipid oxidation 5.1020 5 yes
GO:0009081 branched-chain amino acid metabolic process 4.5918 4 yes
GO:0072330 monocarboxylic acid biosynthetic process 4.0816 6 yes
GO:0009083 branched-chain amino acid catabolic process 4.0816 5 yes
GO:0051259 protein complex oligomerization 4.0816 6 yes
GO:0051260 protein homooligomerization 3.5714 7 yes
GO:0010467 gene expression 3.0612 5 yes
GO:0008202 steroid metabolic process 2.5510 4 yes
GO:1901617 organic hydroxy compound biosynthetic process 2.0408 4 yes
GO:0000959 mitochondrial RNA metabolic process 2.0408 6 yes
GO:0051262 protein tetramerization 2.0408 7 yes
GO:0051289 protein homotetramerization 2.0408 8 yes
GO:0006549 isoleucine metabolic process 1.5306 5 yes
GO:0006550 isoleucine catabolic process 1.5306 6 yes
GO:0009451 RNA modification 1.5306 5 yes
GO:0070901 mitochondrial tRNA methylation 1.0204 6 yes
GO:0090646 mitochondrial tRNA processing 1.0204 7 yes
GO:0097745 mitochondrial tRNA 5-end processing 1.0204 8 yes
GO:0099116 tRNA 5-end processing 1.0204 7 yes
GO:0140053 mitochondrial gene expression 1.0204 6 yes
GO:1900864 mitochondrial RNA modification 1.0204 6 yes
GO:1990180 mitochondrial tRNA 3-end processing 1.0204 8 yes
GO:0000963 mitochondrial RNA processing 1.0204 7 yes
GO:0000964 mitochondrial RNA 5-end processing 1.0204 8 yes
GO:0000965 mitochondrial RNA 3-end processing 1.0204 8 yes
GO:0000966 RNA 5-end processing 1.0204 7 yes
GO:0001510 RNA methylation 1.0204 4 yes
GO:0006399 tRNA metabolic process 1.0204 6 yes
GO:0006400 tRNA modification 1.0204 6 yes
GO:0006694 steroid biosynthetic process 1.0204 5 yes
GO:0006699 bile acid biosynthetic process 1.0204 5 yes
GO:0008033 tRNA processing 1.0204 6 yes
GO:0008206 bile acid metabolic process 1.0204 4 yes
GO:0030488 tRNA methylation 1.0204 5 yes
GO:0031123 RNA 3-end processing 1.0204 7 yes
GO:0042780 tRNA 3-end processing 1.0204 7 yes
GO:0062173 brexanolone metabolic process 1.0204 4 yes
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process 1.0204 7 yes
GO:0070900 mitochondrial tRNA modification 1.0204 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TM10C_HUMAN [view interactions] Low throughput no yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
EF2_HUMAN [view entry] [view interactions] Low throughput yes yes
PINK1_HUMAN [view interactions] Low throughput no yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
HTRA2_HUMAN [view interactions] Low throughput no yes
TOM20_HUMAN [view entry] [view interactions] Low throughput yes yes
TOM40_HUMAN [view interactions] Low throughput no yes
TOM22_HUMAN [view interactions] Low throughput no yes
SUMF1_HUMAN [view interactions] Low throughput no yes
MRPP3_HUMAN [view interactions] Low throughput no yes
HCD2_HUMAN [view entry] [view interactions] Low throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
MRES1_HUMAN [view interactions] High throughput no yes
CYTC_HUMAN [view entry] [view interactions] High throughput yes yes
EFGM_HUMAN [view interactions] High throughput no yes
ODPAT_HUMAN [view interactions] High throughput no no
HINT2_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
A2MG_HUMAN [view interactions] High throughput no yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
ALDOC_HUMAN [view entry] [view interactions] High throughput yes yes
MET17_HUMAN [view interactions] High throughput no yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
RT26_HUMAN [view interactions] High throughput no yes
AL3A1_HUMAN [view interactions] High throughput no no
RRFM_HUMAN [view interactions] High throughput no yes
FUMH_HUMAN [view entry] [view interactions] High throughput yes yes
MTEF3_HUMAN [view interactions] High throughput no no
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
MTG2_HUMAN [view interactions] High throughput no yes
IDHC_HUMAN [view interactions] High throughput no no
IF2M_HUMAN [view interactions] High throughput no yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
RF1ML_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
KCRM_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
FAF1_HUMAN [view interactions] High throughput no yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
RUSD4_HUMAN [view interactions] High throughput no yes
UB2D1_HUMAN [view interactions] High throughput no yes
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
NDUV2_HUMAN [view entry] [view interactions] High throughput yes yes
TACO1_HUMAN [view interactions] High throughput no yes
H2AX_HUMAN [view interactions] High throughput no yes
NDUS2_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD4_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
VATL_HUMAN [view interactions] High throughput no no
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
TMM70_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
VA0E1_HUMAN [view interactions] High throughput no no
TRUB2_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
VATF_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
ICT1_HUMAN [view interactions] High throughput no yes
LDHC_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
OTUB1_HUMAN [view interactions] High throughput no yes
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
CLPP_HUMAN [view interactions] High throughput no yes
SIR4_HUMAN [view interactions] High throughput no yes
GSTM1_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
GSTA1_HUMAN [view interactions] High throughput no no
DJC15_HUMAN [view interactions] High throughput no no
NAA11_HUMAN [view interactions] High throughput no no
GSTA2_HUMAN [view interactions] High throughput no no
HSC20_HUMAN [view interactions] High throughput no yes
EIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
GSTA5_HUMAN [view interactions] High throughput no no
ATG5_HUMAN [view entry] [view interactions] High throughput yes no
SRP72_HUMAN [view interactions] High throughput no yes
GSTA3_HUMAN [view interactions] High throughput no no
SYAM_HUMAN [view interactions] High throughput no yes
NOP56_HUMAN [view interactions] High throughput no yes
IPYR2_HUMAN [view interactions] High throughput no yes
COIL_HUMAN [view interactions] High throughput no yes
IGHG1_HUMAN [view interactions] High throughput no no
GATM_HUMAN [view interactions] High throughput no no
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
IGHG2_HUMAN [view interactions] High throughput no no
OAT_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
FL2D_HUMAN [view interactions] High throughput no yes
ACS2A_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
NEK4_HUMAN [view interactions] High throughput no yes
ACS2B_HUMAN [view interactions] High throughput no no
PER2_HUMAN [view interactions] High throughput no yes
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
ACADV_HUMAN [view interactions] High throughput no yes
HROB_HUMAN [view interactions] High throughput no yes
RHG09_HUMAN [view interactions] High throughput no no
CPT2_HUMAN [view entry] [view interactions] High throughput yes yes
ARL11_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
HCDH_HUMAN [view entry] [view interactions] High throughput yes yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
ACADL_HUMAN [view interactions] High throughput no no
PCDH7_HUMAN [view entry] [view interactions] High throughput yes no
TAGL_HUMAN [view interactions] High throughput no no
ACOX1_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
ACADM_HUMAN [view interactions] High throughput no yes
DCAF4_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
ACD10_HUMAN [view interactions] High throughput no no
DET1_HUMAN [view interactions] High throughput no no
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
ACS2L_HUMAN [view interactions] High throughput no yes
SMU1_HUMAN [view interactions] High throughput no yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
ECH1_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
ARGI2_HUMAN [view interactions] High throughput no yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
SUCHY_HUMAN [view interactions] High throughput no yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
ODB2_HUMAN [view entry] [view interactions] High throughput yes yes
H2A1B_HUMAN [view interactions] High throughput no yes
DHTK1_HUMAN [view interactions] High throughput no no
3HIDH_HUMAN [view interactions] High throughput no yes
HBA_HUMAN [view interactions] High throughput no no
HGD_HUMAN [view interactions] High throughput no no
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
MCCB_HUMAN [view entry] [view interactions] High throughput yes yes
PIMT_HUMAN [view entry] [view interactions] High throughput yes yes
MCCA_HUMAN [view entry] [view interactions] High throughput yes yes
UB2V1_HUMAN [view entry] [view interactions] High throughput yes no
SUOX_HUMAN [view interactions] High throughput no no
PRDX6_HUMAN [view entry] [view interactions] High throughput yes yes
PCCA_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
FAAA_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
PGK1_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3I_HUMAN [view interactions] High throughput no yes
PGAM1_HUMAN [view entry] [view interactions] High throughput yes yes
ML12A_HUMAN [view interactions] High throughput no no
PGAM2_HUMAN [view entry] [view interactions] High throughput yes no
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
SDHB_HUMAN [view interactions] High throughput no yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
BAX_HUMAN [view interactions] High throughput no yes
SUCB2_HUMAN [view interactions] High throughput no no
NOP10_HUMAN [view interactions] High throughput no yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
RUVB2_HUMAN [view interactions] High throughput no yes
ETFA_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD7_HUMAN [view interactions] High throughput no yes
ACY1_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
ACMSD_HUMAN [view interactions] High throughput no no
PTBP1_HUMAN [view interactions] High throughput no no
EST3_HUMAN [view interactions] High throughput no yes
GDIR1_HUMAN [view entry] [view interactions] High throughput yes yes
LRP2_HUMAN [view interactions] High throughput no no
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
LPP60_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
ARLY_HUMAN [view interactions] High throughput no no
PSD11_HUMAN [view entry] [view interactions] High throughput yes yes
ASSY_HUMAN [view interactions] High throughput no yes
PSME2_HUMAN [view interactions] High throughput no no
GPX1_HUMAN [view entry] [view interactions] High throughput yes yes
NH2L1_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
ILF2_HUMAN [view interactions] High throughput no yes
PRDX5_HUMAN [view entry] [view interactions] High throughput yes yes
MCA3_HUMAN [view interactions] High throughput no yes
LDHA_HUMAN [view entry] [view interactions] High throughput yes yes
PDIA6_HUMAN [view entry] [view interactions] High throughput yes yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
XRCC6_HUMAN [view interactions] High throughput no yes
ENOG_HUMAN [view entry] [view interactions] High throughput yes yes
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
KPYM_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
GSTA4_HUMAN [view interactions] High throughput no yes
PRDX3_HUMAN [view interactions] High throughput no yes
GSTM2_HUMAN [view entry] [view interactions] High throughput yes yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
PRS10_HUMAN [view interactions] High throughput no yes
GSTM5_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
HBB_HUMAN [view interactions] High throughput no no
GSTT1_HUMAN [view interactions] High throughput no no
CDK1_HUMAN [view interactions] High throughput no no
FABPL_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
HSPB2_HUMAN [view interactions] High throughput no yes
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB6_HUMAN [view interactions] High throughput no no
HGB1A_HUMAN [view interactions] High throughput no no
IVD_HUMAN [view interactions] High throughput no yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
MYH4_HUMAN [view interactions] High throughput no no
MOB1B_HUMAN [view interactions] High throughput no yes
PUR6_HUMAN [view entry] [view interactions] High throughput yes yes
PIPNB_HUMAN [view interactions] High throughput no no
ADH4_HUMAN [view interactions] High throughput no no
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] High throughput yes yes
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
CAH3_HUMAN [view interactions] High throughput no no
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
PYGB_HUMAN [view entry] [view interactions] High throughput yes no
HPRT_HUMAN [view interactions] High throughput no yes
THIM_HUMAN [view interactions] High throughput no yes
PRS8_HUMAN [view interactions] High throughput no yes
GSTO1_HUMAN [view entry] [view interactions] High throughput yes yes
SYDC_HUMAN [view interactions] High throughput no yes
ACADS_HUMAN [view interactions] High throughput no yes
THIL_HUMAN [view entry] [view interactions] High throughput yes yes
HMCS1_HUMAN [view interactions] High throughput no yes
ACTBM_HUMAN [view interactions] High throughput no no
DUS26_HUMAN [view interactions] High throughput no yes
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
NACAM_HUMAN [view interactions] High throughput no no
RA1L2_HUMAN [view interactions] High throughput no no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
SYK_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
PRP8_HUMAN [view interactions] High throughput no yes
H2A1D_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
AAR2_HUMAN [view interactions] High throughput no no
SPIN1_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
H90B3_HUMAN [view interactions] High throughput no no
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
RALY_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HNRH3_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
RPAB1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
HNRDL_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
TMEDA_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
RECQ4_HUMAN [view interactions] High throughput no yes
PRP19_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
RC3H1_HUMAN [view interactions] High throughput no yes
MCM3_HUMAN [view interactions] High throughput no no
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
RPAB3_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
EF1B_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
ANO7_HUMAN [view interactions] High throughput no no
RNPS1_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
PSMD3_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
HDAC1_HUMAN [view interactions] High throughput no no
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
CPVL_HUMAN [view interactions] High throughput no no
SIR3_HUMAN [view interactions] High throughput no yes
CHTOP_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
XRCC5_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SF3B6_HUMAN [view interactions] High throughput no yes
SERB1_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
MYL1_HUMAN [view interactions] High throughput no no
RHG36_HUMAN [view interactions] High throughput no yes
NAA50_HUMAN [view interactions] High throughput no yes
ARHGF_HUMAN [view entry] [view interactions] High throughput yes no
RMXL2_HUMAN [view interactions] High throughput no no
MYO9A_HUMAN [view entry] [view interactions] High throughput yes yes
SYAC_HUMAN [view interactions] High throughput no yes
STA13_HUMAN [view interactions] High throughput no yes
PSD12_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
EIF3D_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
M4K1_HUMAN [view interactions] High throughput no no
CHM4C_HUMAN [view interactions] High throughput no yes
BACH_HUMAN [view entry] [view interactions] High throughput yes yes
ECT2_HUMAN [view interactions] High throughput no no
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
METK2_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
PLP2_HUMAN [view interactions] High throughput no yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
COPE_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
WDR76_HUMAN [view interactions] High throughput no no
RTCB_HUMAN [view interactions] High throughput no yes
PO2F1_HUMAN [view interactions] High throughput no yes
CH10_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
CSN8_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
SERPH_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
MCM4_HUMAN [view interactions] High throughput no yes
LA_HUMAN [view interactions] High throughput no yes
BUB3_HUMAN [view interactions] High throughput no yes
FGD5_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
ZN363_HUMAN [view interactions] High throughput no yes
PSME3_HUMAN [view interactions] High throughput no yes
BAG1_HUMAN [view interactions] High throughput no yes
RBBP7_HUMAN [view interactions] High throughput no yes
HERC5_HUMAN [view interactions] High throughput no yes
CD2B2_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
HS905_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SAE2_HUMAN [view interactions] High throughput no yes
RHOJ_HUMAN [view interactions] High throughput no yes
FEN1_HUMAN [view interactions] High throughput no yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
BID_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
NAMPT_HUMAN [view interactions] High throughput no no
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
THOC4_HUMAN [view interactions] High throughput no no
ANM1_HUMAN [view interactions] High throughput no yes
PSMD6_HUMAN [view interactions] High throughput no yes
TLS1_HUMAN [view interactions] High throughput no yes
ENPLL_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
PERI_HUMAN [view entry] [view interactions] High throughput yes no
ZRAN1_HUMAN [view interactions] High throughput no yes
ROAA_HUMAN [view entry] [view interactions] High throughput yes yes
BAP1_HUMAN [view interactions] High throughput no yes
CPSF6_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
PRS6B_HUMAN [view interactions] High throughput no yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
ENOB_HUMAN [view entry] [view interactions] High throughput yes no
ACE2_HUMAN [view interactions] High throughput no no
PI42C_HUMAN [view interactions] High throughput no yes
PARPT_HUMAN [view interactions] High throughput no no
DKC1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
NOP58_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL2_HUMAN [view interactions] High throughput no yes
ASXL2_HUMAN [view interactions] High throughput no no
PYRG1_HUMAN [view interactions] High throughput no no
ASXL3_HUMAN [view interactions] High throughput no no
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
PIAS1_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP1_HUMAN [view interactions] High throughput no yes
TET5C_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
RICTR_HUMAN [view interactions] High throughput no yes
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
SMC5_HUMAN [view interactions] High throughput no yes
PDC6I_HUMAN [view entry] [view interactions] High throughput yes yes
RECQ1_HUMAN [view interactions] High throughput no yes
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2H_HUMAN [view interactions] High throughput no yes
CCAR2_HUMAN [view interactions] High throughput no yes
SPRNG_HUMAN [view interactions] High throughput no yes
DD19A_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
B2L14_HUMAN [view interactions] High throughput no yes
TGDS_HUMAN [view interactions] High throughput no yes
NCF1_HUMAN [view interactions] High throughput no no
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
TF7L2_HUMAN [view interactions] High throughput no yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
M3K7_HUMAN [view interactions] High throughput no yes
ALDR_HUMAN [view interactions] High throughput no no
KSYK_HUMAN [view interactions] High throughput no no
AK1BF_HUMAN [view interactions] High throughput no no
ARFG2_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
ARFG3_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
GDIR3_HUMAN [view interactions] High throughput no no
GGYF1_HUMAN [view interactions] High throughput no yes
ARPC3_HUMAN [view entry] [view interactions] High throughput yes yes
TLK2_HUMAN [view interactions] High throughput no no
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
CP135_HUMAN [view interactions] High throughput no no
5MP2_HUMAN [view interactions] High throughput no yes
5MP1_HUMAN [view interactions] High throughput no no
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
CALU_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CLIC1_HUMAN [view interactions] High throughput no no
CSN5_HUMAN [view interactions] High throughput no yes
FABP5_HUMAN [view entry] [view interactions] High throughput yes no
CUL4B_HUMAN [view interactions] High throughput no yes
FKBP2_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
GPX4_HUMAN [view entry] [view interactions] High throughput yes no
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD3_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
PURA2_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
AT1B3_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
VATH_HUMAN [view entry] [view interactions] High throughput yes yes
AKIP_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
RNZ2_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
PDK1_HUMAN [view interactions] High throughput no yes
FKB1A_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
FKB1B_HUMAN [view entry] [view interactions] High throughput yes yes
TR61B_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
DDR2_HUMAN [view interactions] High throughput no no
MOES_HUMAN [view entry] [view interactions] High throughput yes no
RET_HUMAN [view interactions] High throughput no yes
PDIA1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
PSB1_HUMAN [view interactions] High throughput no yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
AL3B1_HUMAN [view interactions] High throughput no yes
RAB8B_HUMAN [view entry] [view interactions] High throughput yes no
ATPA_HUMAN [view interactions] High throughput no yes
RCN1_HUMAN [view interactions] High throughput no yes
CPSM_HUMAN [view interactions] High throughput no no
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
TPD54_HUMAN [view interactions] High throughput no yes
ETFD_HUMAN [view entry] [view interactions] High throughput yes yes
INO1_HUMAN [view interactions] High throughput no no
DHE3_HUMAN [view entry] [view interactions] High throughput yes yes
MYL6_HUMAN [view entry] [view interactions] High throughput yes no
HMGCL_HUMAN [view interactions] High throughput no yes
PPIB_HUMAN [view entry] [view interactions] High throughput yes yes
HMCS2_HUMAN [view interactions] High throughput no no
DHPR_HUMAN [view entry] [view interactions] High throughput yes no
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
SC31A_HUMAN [view entry] [view interactions] High throughput yes yes
ODPX_HUMAN [view entry] [view interactions] High throughput yes yes
S12A4_HUMAN [view interactions] High throughput no yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
TAGL3_HUMAN [view entry] [view interactions] High throughput yes yes
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
GLNA_HUMAN [view entry] [view interactions] High throughput yes yes
TRIP6_HUMAN [view interactions] High throughput no yes
MDHC_HUMAN [view entry] [view interactions] High throughput yes yes
UCHL3_HUMAN [view interactions] High throughput no yes
PYGL_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
CIKS_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
TRAF5_HUMAN [view interactions] High throughput no yes
RINI_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view entry] [view interactions] High throughput yes yes
FLNC_HUMAN [view entry] [view interactions] High throughput yes no
CATA_HUMAN [view entry] [view interactions] High throughput yes no
KGUA_HUMAN [view entry] [view interactions] High throughput yes yes
CUBN_HUMAN [view interactions] High throughput no no
SCYL2_HUMAN [view interactions] High throughput no yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
AGR3_HUMAN [view interactions] High throughput no no
HEM2_HUMAN [view interactions] High throughput no no
FUBP1_HUMAN [view interactions] High throughput no yes
HDAC5_HUMAN [view interactions] High throughput no yes
MTND_HUMAN [view interactions] High throughput no yes
HDGF_HUMAN [view interactions] High throughput no yes
GLTP_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
MRM1_HUMAN [view interactions] High throughput no no
WWOX_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
ASB1_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
MTRFR_HUMAN [view interactions] High throughput no yes
GRSF1_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
HUWE1_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
GAL3A_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no