PSMD1_HUMAN
Evidence for PS localization
Functions
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PSMD1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 29.8077 | 4 | no |
| GO:0017076 | purine nucleotide binding | 26.9231 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 26.9231 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.9615 | 4 | no |
| GO:0019900 | kinase binding | 25.0000 | 4 | no |
| GO:0019901 | protein kinase binding | 23.0769 | 5 | no |
| GO:0031625 | ubiquitin protein ligase binding | 22.1154 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 22.1154 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PSMD1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.8077 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.9231 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 50.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 44.2308 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 43.2692 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 42.3077 | 4 | no |
| GO:0010646 | regulation of cell communication | 41.3462 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.3846 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.4615 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.5769 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 34.6154 | 4 | no |
| GO:0022607 | cellular component assembly | 34.6154 | 4 | no |
| GO:0010941 | regulation of cell death | 33.6538 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 31.7308 | 5 | no |
| GO:0006996 | organelle organization | 31.7308 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 31.7308 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 31.7308 | 5 | no |
| GO:0009894 | regulation of catabolic process | 30.7692 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 28.8462 | 4 | no |
| GO:0010468 | regulation of gene expression | 28.8462 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.8462 | 5 | no |
| GO:0031399 | regulation of protein modification process | 28.8462 | 6 | no |
| GO:0043412 | macromolecule modification | 28.8462 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.8462 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 28.8462 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.8462 | 4 | no |
| GO:0036211 | protein modification process | 27.8846 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.8846 | 5 | no |
| GO:0023056 | positive regulation of signaling | 27.8846 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 26.9231 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.9231 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.9231 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.9231 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.9231 | 5 | no |
| GO:0009057 | macromolecule catabolic process | 25.9615 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.9615 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.9615 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.9615 | 4 | no |
| GO:0008104 | protein localization | 25.9615 | 4 | no |
| GO:0006508 | proteolysis | 25.0000 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 25.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0044265 | cellular macromolecule catabolic process | 24.0385 | 4 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 24.0385 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 24.0385 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.0385 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.0385 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 24.0385 | 5 | no |
| GO:0019941 | modification-dependent protein catabolic process | 23.0769 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 23.0769 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 22.1154 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.1154 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 22.1154 | 4 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 22.1154 | 4 | no |
| GO:0060548 | negative regulation of cell death | 21.1538 | 5 | no |
| GO:0042176 | regulation of protein catabolic process | 20.1923 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 20.1923 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 20.1923 | 7 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.1923 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 20.1923 | 5 | no |
| GO:0071702 | organic substance transport | 20.1923 | 4 | no |
| GO:0071705 | nitrogen compound transport | 20.1923 | 4 | no |
| GO:0032880 | regulation of protein localization | 20.1923 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.1923 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 20.1923 | 5 | no |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 19.2308 | 7 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 18.2692 | 4 | yes |
| GO:0030163 | protein catabolic process | 16.3462 | 4 | yes |
| GO:0010498 | proteasomal protein catabolic process | 15.3846 | 5 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 13.4615 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PSMD1_HUMAN |
|---|---|---|---|---|
| DOID:10595 | Charcot-Marie-Tooth disease | 2.8846 | 6 | no |
| DOID:440 | neuromuscular disease | 2.8846 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.8846 | 3 | no |
| DOID:870 | neuropathy | 2.8846 | 4 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.9231 | 7 | no |
| DOID:1289 | neurodegenerative disease | 1.9231 | 4 | no |
| DOID:331 | central nervous system disease | 1.9231 | 3 | no |
| DOID:0050686 | organ system cancer | 1.9231 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ADRM1_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMD4_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMD5_HUMAN | [view interactions] | Low throughput | no | yes |
| PRS8_HUMAN | [view interactions] | Low throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRS4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | Low throughput | no | yes |
| ZFAN1_HUMAN | [view interactions] | Low throughput | no | yes |
| MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
| PRS6B_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB7_HUMAN | [view interactions] | Low throughput | no | yes |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| PGH2_HUMAN | [view interactions] | Low throughput | no | no |
| PRS7_HUMAN | [view interactions] | Low throughput | no | yes |
| ZFN2A_HUMAN | [view interactions] | Low throughput | no | yes |
| RBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAG1_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERCC8_HUMAN | [view interactions] | Low throughput | no | no |
| ERCC6_HUMAN | [view interactions] | Low throughput | no | no |
| PSA3_HUMAN | [view interactions] | Low throughput | no | no |
| PSA6_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA7_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| CDK12_HUMAN | [view interactions] | High throughput | no | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| HBS1L_HUMAN | [view interactions] | High throughput | no | yes |
| INT5_HUMAN | [view interactions] | High throughput | no | no |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| MED28_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT63_HUMAN | [view interactions] | High throughput | no | yes |
| RM16_HUMAN | [view interactions] | High throughput | no | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| RM46_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| RT25_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| RT05_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| PELO_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| PPIE_HUMAN | [view interactions] | High throughput | no | yes |
| PSB5_HUMAN | [view interactions] | High throughput | no | yes |
| PPWD1_HUMAN | [view interactions] | High throughput | no | yes |
| ROMO1_HUMAN | [view interactions] | High throughput | no | yes |
| PSB4_HUMAN | [view interactions] | High throughput | no | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| RL27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBCP1_HUMAN | [view interactions] | High throughput | no | yes |
| RTF1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| ALPK3_HUMAN | [view interactions] | High throughput | no | yes |
| SEH1_HUMAN | [view interactions] | High throughput | no | no |
| MBD4_HUMAN | [view interactions] | High throughput | no | yes |
| TGIF2_HUMAN | [view interactions] | High throughput | no | no |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| SAE2_HUMAN | [view interactions] | High throughput | no | yes |
| VPS4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS72_HUMAN | [view interactions] | High throughput | no | no |
| TP4A1_HUMAN | [view interactions] | High throughput | no | no |
| WDR61_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLI2_HUMAN | [view interactions] | High throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLF15_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| TAL1_HUMAN | [view interactions] | High throughput | no | no |
| PSME2_HUMAN | [view interactions] | High throughput | no | no |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECD_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TR10D_HUMAN | [view interactions] | High throughput | no | no |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| PAAF1_HUMAN | [view interactions] | High throughput | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAR3_HUMAN | [view interactions] | High throughput | no | yes |
| RBM12_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RO52_HUMAN | [view interactions] | High throughput | no | yes |
| LIPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RS12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| RS15A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSMA8_HUMAN | [view interactions] | High throughput | no | no |
| ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
| PSB8_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK20_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| CILK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF24_HUMAN | [view interactions] | High throughput | no | yes |
| CD11A_HUMAN | [view interactions] | High throughput | no | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| AKA10_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| CAN3_HUMAN | [view interactions] | High throughput | no | no |
| SYMPK_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXOSX_HUMAN | [view interactions] | High throughput | no | yes |
| PPARG_HUMAN | [view interactions] | High throughput | no | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MKS3_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| CP2C9_HUMAN | [view interactions] | High throughput | no | no |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| NANP8_HUMAN | [view interactions] | High throughput | no | no |
| RPA49_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| ACK1_HUMAN | [view interactions] | High throughput | no | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBLB_HUMAN | [view interactions] | High throughput | no | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| PSA2_HUMAN | [view interactions] | High throughput | no | yes |
| EPAS1_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| SNAI2_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| CC74B_HUMAN | [view interactions] | High throughput | no | no |
| PSB9_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN2_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| PSB3_HUMAN | [view interactions] | High throughput | no | yes |
| CCD92_HUMAN | [view interactions] | High throughput | no | yes |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| PTN6_HUMAN | [view interactions] | High throughput | no | no |
| DUS15_HUMAN | [view interactions] | High throughput | no | no |
| PTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| DCA11_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| TRI11_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| AL1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL4_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| BMAL1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| DUS1_HUMAN | [view interactions] | High throughput | no | no |
| DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EYA3_HUMAN | [view interactions] | High throughput | no | no |
| MTM1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| SMC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAG2_HUMAN | [view interactions] | High throughput | no | yes |
| PDS5A_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| MAF_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| TMM31_HUMAN | [view interactions] | High throughput | no | no |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD9_HUMAN | [view interactions] | High throughput | no | yes |
| CC74A_HUMAN | [view interactions] | High throughput | no | no |
| DRB3_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT1_HUMAN | [view interactions] | High throughput | no | yes |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| COPZ1_HUMAN | [view interactions] | High throughput | no | no |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA5_HUMAN | [view interactions] | High throughput | no | yes |
| PSB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME4_HUMAN | [view interactions] | High throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMF1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMG1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMG3_HUMAN | [view interactions] | High throughput | no | yes |
| SEML_HUMAN | [view interactions] | High throughput | no | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| BLM_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| BDP1_HUMAN | [view interactions] | High throughput | no | no |
| BD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| SYCC_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE1_HUMAN | [view interactions] | Computational | no | yes |
| RUNX2_HUMAN | [view interactions] | Computational | no | no |
| SPA5L_HUMAN | [view interactions] | Computational | no | yes |
| AFG2H_HUMAN | [view interactions] | Computational | no | yes |
| M3K14_HUMAN | [view interactions] | Computational | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBFD1_HUMAN | [view interactions] | Computational | no | no |
| RACK1_HUMAN | [view interactions] | Computational | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COP1_HUMAN | [view interactions] | Computational | no | no |
| CCND1_HUMAN | [view interactions] | Computational | no | yes |
| PSB10_HUMAN | [view interactions] | Computational | no | no |
| GEMI_HUMAN | [view interactions] | Computational | no | no |
| OAZ2_HUMAN | [view interactions] | Computational | no | no |
| PSB11_HUMAN | [view interactions] | Computational | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ATD2B_HUMAN | [view interactions] | Computational | no | yes |
| IKBA_HUMAN | [view interactions] | Computational | no | yes |
| GLI1_HUMAN | [view interactions] | Computational | no | no |
| SPRE2_HUMAN | [view interactions] | Computational | no | yes |
| MPIP1_HUMAN | [view interactions] | Computational | no | no |
| SUFU_HUMAN | [view interactions] | Computational | no | yes |
| FBXL7_HUMAN | [view interactions] | Computational | no | no |
| PRIC1_HUMAN | [view interactions] | Computational | no | yes |
| MYSM1_HUMAN | [view interactions] | Computational | no | yes |
| ORC1_HUMAN | [view interactions] | Computational | no | yes |
| NFKB1_HUMAN | [view interactions] | Computational | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NOTC4_HUMAN | [view interactions] | Computational | no | no |
| DCOR_HUMAN | [view interactions] | Computational | no | yes |
| ANR42_HUMAN | [view interactions] | Computational | no | yes |
| NUMB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CDC6_HUMAN | [view interactions] | Computational | no | yes |
| SPRE3_HUMAN | [view interactions] | Computational | no | no |
| IF2B_HUMAN | [view interactions] | Computational | no | yes |
| PAK2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RUNX3_HUMAN | [view interactions] | Computational | no | no |
| SHH_HUMAN | [view interactions] | Computational | no | no |
| RS2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLI3_HUMAN | [view interactions] | Computational | no | yes |
| BRCC3_HUMAN | [view interactions] | Computational | no | no |
| P73_HUMAN | [view interactions] | Computational | no | no |
| TCPD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| OAZ1_HUMAN | [view interactions] | Computational | no | yes |