IF4G1_HUMAN
Evidence for PS localization
Functions
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002090 | LIG_eIF4E_1 | LIG | 612 | 618 | - |
| ELMI002090 | LIG_eIF4E_1 | LIG | 612 | 618 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IF4G1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 50.7692 | 4 | yes |
| GO:0043168 | anion binding | 26.9231 | 4 | yes |
| GO:0000166 | nucleotide binding | 26.1538 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 25.3846 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 25.3846 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.3846 | 4 | yes |
| GO:0003729 | mRNA binding | 22.3077 | 5 | yes |
| GO:0005524 | ATP binding | 22.3077 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.3077 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.3077 | 5 | yes |
| GO:0045296 | cadherin binding | 22.3077 | 4 | no |
| GO:0003743 | translation initiation factor activity | 7.6923 | 4 | yes |
| GO:0008190 | eukaryotic initiation factor 4E binding | 3.8462 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IF4G1_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 61.5385 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 58.4615 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 56.9231 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 56.9231 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 53.0769 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 51.5385 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 51.5385 | 5 | yes |
| GO:0010468 | regulation of gene expression | 50.0000 | 6 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 46.9231 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 39.2308 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 38.4615 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.4615 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 37.6923 | 4 | yes |
| GO:0010646 | regulation of cell communication | 35.3846 | 4 | no |
| GO:0022607 | cellular component assembly | 35.3846 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 35.3846 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 35.3846 | 5 | yes |
| GO:0006996 | organelle organization | 34.6154 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 33.8462 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.3077 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 32.3077 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 31.5385 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.5385 | 6 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 31.5385 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 30.7692 | 5 | no |
| GO:0009966 | regulation of signal transduction | 28.4615 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 28.4615 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 27.6923 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 27.6923 | 6 | yes |
| GO:0008104 | protein localization | 26.9231 | 4 | no |
| GO:0009894 | regulation of catabolic process | 26.1538 | 4 | yes |
| GO:0090304 | nucleic acid metabolic process | 25.3846 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 24.6154 | 7 | yes |
| GO:0031399 | regulation of protein modification process | 24.6154 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 23.8462 | 4 | no |
| GO:0009059 | macromolecule biosynthetic process | 23.8462 | 4 | yes |
| GO:0010608 | post-transcriptional regulation of gene expression | 23.8462 | 7 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 23.0769 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.0769 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.0769 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 23.0769 | 6 | yes |
| GO:0071702 | organic substance transport | 22.3077 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 22.3077 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 21.5385 | 4 | no |
| GO:0006417 | regulation of translation | 21.5385 | 6 | yes |
| GO:0023056 | positive regulation of signaling | 20.7692 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 20.7692 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 20.7692 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.7692 | 5 | no |
| GO:0010629 | negative regulation of gene expression | 20.7692 | 7 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 20.7692 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.7692 | 5 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 20.7692 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 19.2308 | 7 | yes |
| GO:0042325 | regulation of phosphorylation | 18.4615 | 7 | yes |
| GO:0045595 | regulation of cell differentiation | 18.4615 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 17.6923 | 7 | yes |
| GO:0006412 | translation | 17.6923 | 4 | yes |
| GO:0032880 | regulation of protein localization | 16.9231 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 16.9231 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 14.6154 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 13.8462 | 6 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 13.8462 | 7 | yes |
| GO:0051094 | positive regulation of developmental process | 13.8462 | 4 | yes |
| GO:0080134 | regulation of response to stress | 13.8462 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 13.0769 | 8 | yes |
| GO:0042327 | positive regulation of phosphorylation | 13.0769 | 8 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 13.0769 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 13.0769 | 5 | yes |
| GO:0045727 | positive regulation of translation | 13.0769 | 7 | yes |
| GO:1903829 | positive regulation of protein localization | 12.3077 | 5 | yes |
| GO:0017148 | negative regulation of translation | 11.5385 | 7 | yes |
| GO:0031400 | negative regulation of protein modification process | 11.5385 | 7 | yes |
| GO:0001558 | regulation of cell growth | 10.7692 | 4 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 10.7692 | 6 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 10.7692 | 7 | yes |
| GO:0006446 | regulation of translational initiation | 10.0000 | 7 | yes |
| GO:0045597 | positive regulation of cell differentiation | 10.0000 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 9.2308 | 5 | yes |
| GO:0010564 | regulation of cell cycle process | 9.2308 | 5 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 8.4615 | 6 | yes |
| GO:0042326 | negative regulation of phosphorylation | 8.4615 | 8 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 7.6923 | 8 | yes |
| GO:0045787 | positive regulation of cell cycle | 7.6923 | 5 | yes |
| GO:0050807 | regulation of synapse organization | 7.6923 | 5 | yes |
| GO:0007346 | regulation of mitotic cell cycle | 6.9231 | 5 | yes |
| GO:0051099 | positive regulation of binding | 6.9231 | 4 | yes |
| GO:0080135 | regulation of cellular response to stress | 6.9231 | 4 | yes |
| GO:0030307 | positive regulation of cell growth | 6.1538 | 5 | yes |
| GO:0031047 | regulatory ncRNA-mediated gene silencing | 6.1538 | 8 | yes |
| GO:0045664 | regulation of neuron differentiation | 6.1538 | 5 | yes |
| GO:0045927 | positive regulation of growth | 6.1538 | 4 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 5.3846 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 5.3846 | 5 | yes |
| GO:0097305 | response to alcohol | 5.3846 | 4 | yes |
| GO:1904377 | positive regulation of protein localization to cell periphery | 4.6154 | 6 | yes |
| GO:0010506 | regulation of autophagy | 4.6154 | 6 | yes |
| GO:0016441 | post-transcriptional gene silencing | 4.6154 | 8 | yes |
| GO:0030182 | neuron differentiation | 4.6154 | 4 | yes |
| GO:0045931 | positive regulation of mitotic cell cycle | 4.6154 | 6 | yes |
| GO:0090068 | positive regulation of cell cycle process | 4.6154 | 6 | yes |
| GO:1901987 | regulation of cell cycle phase transition | 4.6154 | 6 | yes |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 3.8462 | 6 | yes |
| GO:0035194 | regulatory ncRNA-mediated post-transcriptional gene silencing | 3.8462 | 9 | yes |
| GO:1901989 | positive regulation of cell cycle phase transition | 3.8462 | 7 | yes |
| GO:1901992 | positive regulation of mitotic cell cycle phase transition | 3.0769 | 7 | yes |
| GO:1902415 | regulation of mRNA binding | 3.0769 | 5 | yes |
| GO:1902416 | positive regulation of mRNA binding | 3.0769 | 6 | yes |
| GO:1905214 | regulation of RNA binding | 3.0769 | 4 | yes |
| GO:1905216 | positive regulation of RNA binding | 3.0769 | 5 | yes |
| GO:0002183 | cytoplasmic translational initiation | 3.0769 | 4 | yes |
| GO:0035195 | miRNA-mediated post-transcriptional gene silencing | 3.0769 | 10 | yes |
| GO:0035278 | miRNA-mediated gene silencing by inhibition of translation | 3.0769 | 8 | yes |
| GO:1901888 | regulation of cell junction assembly | 3.0769 | 5 | yes |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 2.3077 | 7 | yes |
| GO:1902808 | positive regulation of cell cycle G1/S phase transition | 2.3077 | 8 | yes |
| GO:1905606 | regulation of presynapse assembly | 2.3077 | 7 | yes |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 2.3077 | 7 | yes |
| GO:0001662 | behavioral fear response | 2.3077 | 4 | yes |
| GO:0010507 | negative regulation of autophagy | 2.3077 | 7 | yes |
| GO:0031330 | negative regulation of cellular catabolic process | 2.3077 | 6 | yes |
| GO:0032056 | positive regulation of translation in response to stress | 2.3077 | 8 | yes |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 2.3077 | 8 | yes |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 2.3077 | 9 | yes |
| GO:0036490 | regulation of translation in response to endoplasmic reticulum stress | 2.3077 | 8 | yes |
| GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress | 2.3077 | 9 | yes |
| GO:0043555 | regulation of translation in response to stress | 2.3077 | 7 | yes |
| GO:0045471 | response to ethanol | 2.3077 | 5 | yes |
| GO:0051963 | regulation of synapse assembly | 2.3077 | 6 | yes |
| GO:0099174 | regulation of presynapse organization | 2.3077 | 6 | yes |
| GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | 2.3077 | 8 | yes |
| GO:1905535 | regulation of eukaryotic translation initiation factor 4F complex assembly | 1.5385 | 6 | yes |
| GO:1905537 | positive regulation of eukaryotic translation initiation factor 4F complex assembly | 1.5385 | 7 | yes |
| GO:1905610 | regulation of mRNA cap binding | 1.5385 | 6 | yes |
| GO:1905612 | positive regulation of mRNA cap binding | 1.5385 | 7 | yes |
| GO:0002191 | cap-dependent translational initiation | 1.5385 | 5 | yes |
| GO:0010799 | regulation of peptidyl-threonine phosphorylation | 1.5385 | 8 | yes |
| GO:0010801 | negative regulation of peptidyl-threonine phosphorylation | 1.5385 | 9 | yes |
| GO:0030324 | lung development | 1.5385 | 4 | yes |
| GO:0045666 | positive regulation of neuron differentiation | 1.5385 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NCBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| MKNK1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RENT2_HUMAN | [view interactions] | Low throughput | no | no |
| REN3B_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4E2_HUMAN | [view interactions] | Low throughput | no | no |
| PDCD4_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR6C_HUMAN | [view interactions] | Low throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HTRA2_HUMAN | [view interactions] | Low throughput | no | yes |
| INT6_HUMAN | [view interactions] | Low throughput | no | yes |
| SF3B3_HUMAN | [view interactions] | Low throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FXR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PUF60_HUMAN | [view interactions] | Low throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| G3BP1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| MKNK2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP10_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3F_HUMAN | [view interactions] | Low throughput | no | yes |
| PDIP3_HUMAN | [view interactions] | Low throughput | no | no |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OTU6B_HUMAN | [view interactions] | Low throughput | no | yes |
| SRSF3_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF1_HUMAN | [view interactions] | Low throughput | no | no |
| EIF3C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3G_HUMAN | [view interactions] | Low throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | Low throughput | no | no |
| EIF3J_HUMAN | [view interactions] | Low throughput | no | yes |
| Z3H7B_HUMAN | [view interactions] | Low throughput | no | no |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3B_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBM4_HUMAN | [view interactions] | Low throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BUB1_HUMAN | [view interactions] | High throughput | no | no |
| GCSP_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD1_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOS2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED28_HUMAN | [view interactions] | High throughput | no | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| YLPM1_HUMAN | [view interactions] | High throughput | no | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM32_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PTTG1_HUMAN | [view interactions] | High throughput | no | no |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAF2_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRN2_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HG2A_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| DDX60_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCH1_HUMAN | [view interactions] | High throughput | no | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB31_HUMAN | [view interactions] | High throughput | no | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| MCA3_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB8_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP1_HUMAN | [view interactions] | High throughput | no | no |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUM3_HUMAN | [view interactions] | High throughput | no | yes |
| NAT10_HUMAN | [view interactions] | High throughput | no | yes |
| PUS7_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| MTREX_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| DPOE1_HUMAN | [view interactions] | High throughput | no | no |
| LN28A_HUMAN | [view interactions] | High throughput | no | no |
| TB182_HUMAN | [view interactions] | High throughput | no | yes |
| CHD8_HUMAN | [view interactions] | High throughput | no | no |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAF1B_HUMAN | [view interactions] | High throughput | no | no |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXB1_HUMAN | [view interactions] | High throughput | no | no |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| FOXL1_HUMAN | [view interactions] | High throughput | no | no |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| NBEL2_HUMAN | [view interactions] | High throughput | no | no |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUNK_HUMAN | [view interactions] | High throughput | no | yes |
| HAT1_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| JIP4_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| PYRG1_HUMAN | [view interactions] | High throughput | no | no |
| CDN2D_HUMAN | [view interactions] | High throughput | no | no |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| A1CF_HUMAN | [view interactions] | High throughput | no | no |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEF1_HUMAN | [view interactions] | High throughput | no | no |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTBP2_HUMAN | [view interactions] | High throughput | no | no |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIB1_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NELFD_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| UBP3_HUMAN | [view interactions] | High throughput | no | no |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| PRI1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| LRBA_HUMAN | [view interactions] | High throughput | no | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| SPSY_HUMAN | [view interactions] | High throughput | no | no |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAMC2_HUMAN | [view interactions] | High throughput | no | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MKRN1_HUMAN | [view interactions] | High throughput | no | no |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLBP_HUMAN | [view interactions] | High throughput | no | yes |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GFRP_HUMAN | [view interactions] | High throughput | no | no |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NF2IP_HUMAN | [view interactions] | High throughput | no | no |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMIL1_HUMAN | [view interactions] | High throughput | no | no |
| GOGA4_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| GAPD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA35_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| LARP4_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| TOPK_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| NADAP_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| RRAGC_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| VPS18_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NRBP_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| Z3H7A_HUMAN | [view interactions] | High throughput | no | no |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| SND1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| CMTR1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| 4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4EBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3D_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3K_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| ANGE1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| IFT22_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC26_HUMAN | [view interactions] | High throughput | no | yes |
| CE350_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CND2_HUMAN | [view interactions] | High throughput | no | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP19_HUMAN | [view interactions] | High throughput | no | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| TOP2A_HUMAN | [view interactions] | High throughput | no | no |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| MSX2_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| IF1AX_HUMAN | [view interactions] | High throughput | no | yes |
| ZFYV9_HUMAN | [view interactions] | High throughput | no | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLPK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CENPU_HUMAN | [view interactions] | High throughput | no | no |
| RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX21_HUMAN | [view interactions] | High throughput | no | yes |
| ASCC2_HUMAN | [view interactions] | High throughput | no | yes |
| GSE1_HUMAN | [view interactions] | High throughput | no | yes |
| EI2BA_HUMAN | [view interactions] | High throughput | no | yes |
| IPO8_HUMAN | [view interactions] | High throughput | no | no |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAMH1_HUMAN | [view interactions] | High throughput | no | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| SRP14_HUMAN | [view interactions] | High throughput | no | no |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLCN2_HUMAN | [view interactions] | High throughput | no | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX50_HUMAN | [view interactions] | High throughput | no | yes |
| SGTB_HUMAN | [view interactions] | High throughput | no | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| RM09_HUMAN | [view interactions] | High throughput | no | yes |
| RS9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| ARP5_HUMAN | [view interactions] | High throughput | no | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H31_HUMAN | [view interactions] | High throughput | no | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DICER_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |