IF4G1_HUMAN
Evidence for PS localization
Functions
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002090 | LIG_eIF4E_1 | LIG | 612 | 618 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IF4G1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 65.0485 | 4 | yes |
| GO:0003729 | mRNA binding | 25.2427 | 5 | yes |
| GO:0017076 | purine nucleotide binding | 25.2427 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 25.2427 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.2427 | 4 | yes |
| GO:0005524 | ATP binding | 22.3301 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.3301 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.3301 | 5 | yes |
| GO:0003743 | translation initiation factor activity | 9.7087 | 4 | yes |
| GO:0008190 | eukaryotic initiation factor 4E binding | 4.8544 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IF4G1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.1942 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 60.1942 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 59.2233 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 59.2233 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 57.2816 | 4 | yes |
| GO:0010468 | regulation of gene expression | 53.3981 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 53.3981 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 47.5728 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 47.5728 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 46.6019 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 46.6019 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 42.7184 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 40.7767 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.7767 | 5 | yes |
| GO:0009059 | macromolecule biosynthetic process | 38.8350 | 4 | yes |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 38.8350 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.8350 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 37.8641 | 5 | yes |
| GO:0043603 | cellular amide metabolic process | 37.8641 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 36.8932 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 36.8932 | 5 | yes |
| GO:0034645 | cellular macromolecule biosynthetic process | 36.8932 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 36.8932 | 5 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 36.8932 | 4 | yes |
| GO:0043604 | amide biosynthetic process | 35.9223 | 5 | yes |
| GO:0006518 | peptide metabolic process | 34.9515 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 34.9515 | 4 | yes |
| GO:0006412 | translation | 33.9806 | 4 | yes |
| GO:0043043 | peptide biosynthetic process | 33.9806 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 33.9806 | 6 | yes |
| GO:0022607 | cellular component assembly | 33.9806 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.0097 | 4 | no |
| GO:0010608 | post-transcriptional regulation of gene expression | 32.0388 | 6 | yes |
| GO:0090304 | nucleic acid metabolic process | 31.0680 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.0680 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 31.0680 | 5 | no |
| GO:2000112 | regulation of cellular macromolecule biosynthetic process | 30.0971 | 6 | yes |
| GO:0002181 | cytoplasmic translation | 30.0971 | 5 | no |
| GO:0006417 | regulation of translation | 29.1262 | 6 | yes |
| GO:0034248 | regulation of cellular amide metabolic process | 29.1262 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 28.1553 | 4 | no |
| GO:0006996 | organelle organization | 28.1553 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 27.1845 | 6 | yes |
| GO:0016070 | RNA metabolic process | 27.1845 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 26.2136 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 25.2427 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.2427 | 6 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 25.2427 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 25.2427 | 6 | no |
| GO:0010629 | negative regulation of gene expression | 25.2427 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 25.2427 | 6 | no |
| GO:0009894 | regulation of catabolic process | 24.2718 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 24.2718 | 6 | yes |
| GO:0010941 | regulation of cell death | 24.2718 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 23.3010 | 6 | yes |
| GO:0006396 | RNA processing | 23.3010 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.3010 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 22.3301 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 22.3301 | 5 | no |
| GO:0071310 | cellular response to organic substance | 22.3301 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.3592 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 21.3592 | 4 | no |
| GO:0043412 | macromolecule modification | 21.3592 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.3883 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 20.3883 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 20.3883 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.3883 | 6 | no |
| GO:0036211 | protein modification process | 20.3883 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 19.4175 | 5 | yes |
| GO:0051726 | regulation of cell cycle | 18.4466 | 4 | yes |
| GO:0031401 | positive regulation of protein modification process | 17.4757 | 7 | yes |
| GO:0034250 | positive regulation of cellular amide metabolic process | 17.4757 | 6 | yes |
| GO:0045727 | positive regulation of translation | 17.4757 | 7 | yes |
| GO:0060548 | negative regulation of cell death | 17.4757 | 5 | yes |
| GO:0080134 | regulation of response to stress | 17.4757 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 16.5049 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 16.5049 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 14.5631 | 7 | yes |
| GO:0006446 | regulation of translational initiation | 14.5631 | 7 | yes |
| GO:0042325 | regulation of phosphorylation | 14.5631 | 7 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 13.5922 | 6 | yes |
| GO:0010942 | positive regulation of cell death | 13.5922 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 13.5922 | 4 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 13.5922 | 7 | yes |
| GO:0080135 | regulation of cellular response to stress | 13.5922 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 12.6214 | 8 | yes |
| GO:0042327 | positive regulation of phosphorylation | 12.6214 | 8 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 12.6214 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 12.6214 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 12.6214 | 4 | yes |
| GO:0045787 | positive regulation of cell cycle | 11.6505 | 5 | yes |
| GO:0001558 | regulation of cell growth | 10.6796 | 4 | yes |
| GO:0007346 | regulation of mitotic cell cycle | 10.6796 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 10.6796 | 5 | yes |
| GO:0031400 | negative regulation of protein modification process | 10.6796 | 7 | yes |
| GO:0010564 | regulation of cell cycle process | 9.7087 | 5 | yes |
| GO:0051099 | positive regulation of binding | 9.7087 | 4 | yes |
| GO:0031330 | negative regulation of cellular catabolic process | 8.7379 | 6 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 8.7379 | 6 | yes |
| GO:0045597 | positive regulation of cell differentiation | 8.7379 | 5 | yes |
| GO:1901214 | regulation of neuron death | 8.7379 | 5 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 7.7670 | 6 | yes |
| GO:0045931 | positive regulation of mitotic cell cycle | 7.7670 | 6 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 7.7670 | 7 | yes |
| GO:0031667 | response to nutrient levels | 6.7961 | 4 | yes |
| GO:0045927 | positive regulation of growth | 6.7961 | 4 | yes |
| GO:0090068 | positive regulation of cell cycle process | 6.7961 | 6 | yes |
| GO:1901987 | regulation of cell cycle phase transition | 6.7961 | 6 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 5.8252 | 8 | yes |
| GO:0030307 | positive regulation of cell growth | 5.8252 | 5 | yes |
| GO:0031669 | cellular response to nutrient levels | 5.8252 | 4 | yes |
| GO:0042326 | negative regulation of phosphorylation | 5.8252 | 8 | yes |
| GO:0050807 | regulation of synapse organization | 5.8252 | 5 | yes |
| GO:1901989 | positive regulation of cell cycle phase transition | 5.8252 | 7 | yes |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 5.8252 | 6 | yes |
| GO:1902415 | regulation of mRNA binding | 5.8252 | 5 | yes |
| GO:1905214 | regulation of RNA binding | 5.8252 | 4 | yes |
| GO:0010506 | regulation of autophagy | 4.8544 | 6 | yes |
| GO:0045664 | regulation of neuron differentiation | 4.8544 | 5 | yes |
| GO:1901215 | negative regulation of neuron death | 4.8544 | 6 | yes |
| GO:1901992 | positive regulation of mitotic cell cycle phase transition | 4.8544 | 7 | yes |
| GO:1902416 | positive regulation of mRNA binding | 4.8544 | 6 | yes |
| GO:1905216 | positive regulation of RNA binding | 4.8544 | 5 | yes |
| GO:0001662 | behavioral fear response | 3.8835 | 4 | yes |
| GO:0002183 | cytoplasmic translational initiation | 3.8835 | 4 | yes |
| GO:0043555 | regulation of translation in response to stress | 3.8835 | 7 | yes |
| GO:0060147 | regulation of post-transcriptional gene silencing | 3.8835 | 6 | yes |
| GO:0060964 | regulation of miRNA-mediated gene silencing | 3.8835 | 8 | yes |
| GO:0060966 | regulation of gene silencing by RNA | 3.8835 | 6 | yes |
| GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | 3.8835 | 8 | yes |
| GO:1900368 | regulation of post-transcriptional gene silencing by RNA | 3.8835 | 7 | yes |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 3.8835 | 7 | yes |
| GO:1902808 | positive regulation of cell cycle G1/S phase transition | 3.8835 | 8 | yes |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 3.8835 | 7 | yes |
| GO:0010507 | negative regulation of autophagy | 2.9126 | 7 | yes |
| GO:0032056 | positive regulation of translation in response to stress | 2.9126 | 8 | yes |
| GO:0036490 | regulation of translation in response to endoplasmic reticulum stress | 2.9126 | 8 | yes |
| GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress | 2.9126 | 9 | yes |
| GO:0051963 | regulation of synapse assembly | 2.9126 | 6 | yes |
| GO:0099174 | regulation of presynapse organization | 2.9126 | 6 | yes |
| GO:1901888 | regulation of cell junction assembly | 2.9126 | 5 | yes |
| GO:1905606 | regulation of presynapse assembly | 2.9126 | 7 | yes |
| GO:0002191 | cap-dependent translational initiation | 1.9417 | 5 | yes |
| GO:0010799 | regulation of peptidyl-threonine phosphorylation | 1.9417 | 8 | yes |
| GO:0010801 | negative regulation of peptidyl-threonine phosphorylation | 1.9417 | 9 | yes |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 1.9417 | 8 | yes |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 1.9417 | 9 | yes |
| GO:0045666 | positive regulation of neuron differentiation | 1.9417 | 6 | yes |
| GO:1905535 | regulation of eukaryotic translation initiation factor 4F complex assembly | 1.9417 | 6 | yes |
| GO:1905537 | positive regulation of eukaryotic translation initiation factor 4F complex assembly | 1.9417 | 7 | yes |
| GO:1905610 | regulation of mRNA cap binding | 1.9417 | 6 | yes |
| GO:1905612 | positive regulation of mRNA cap binding | 1.9417 | 7 | yes |
| GO:1905696 | regulation of polysome binding | 1.9417 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in IF4G1_HUMAN |
|---|---|---|---|---|
| DOID:12377 | spinal muscular atrophy | 1.9417 | 6 | no |
| DOID:1289 | neurodegenerative disease | 1.9417 | 4 | no |
| DOID:231 | motor neuron disease | 1.9417 | 5 | no |
| DOID:331 | central nervous system disease | 1.9417 | 3 | no |
| DOID:37 | skin disease | 1.9417 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| MKNK2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP10_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3F_HUMAN | [view interactions] | Low throughput | no | yes |
| PDIP3_HUMAN | [view interactions] | Low throughput | no | no |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OTU6B_HUMAN | [view interactions] | Low throughput | no | yes |
| SRSF3_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF1_HUMAN | [view interactions] | Low throughput | no | no |
| EIF3C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3G_HUMAN | [view interactions] | Low throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HTRA2_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | Low throughput | no | no |
| EIF3J_HUMAN | [view interactions] | Low throughput | no | yes |
| Z3H7B_HUMAN | [view interactions] | Low throughput | no | no |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3B_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBM4_HUMAN | [view interactions] | Low throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NCBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| MKNK1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| REN3B_HUMAN | [view interactions] | Low throughput | no | yes |
| RENT2_HUMAN | [view interactions] | Low throughput | no | no |
| IF4G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4E2_HUMAN | [view interactions] | Low throughput | no | no |
| PDCD4_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR6C_HUMAN | [view interactions] | Low throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| INT6_HUMAN | [view interactions] | Low throughput | no | yes |
| SF3B3_HUMAN | [view interactions] | Low throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PUF60_HUMAN | [view interactions] | Low throughput | no | yes |
| FXR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| G3BP1_HUMAN | [view interactions] | Low throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2D_HUMAN | [view interactions] | High throughput | no | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| A1CF_HUMAN | [view interactions] | High throughput | no | no |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| PEF1_HUMAN | [view interactions] | High throughput | no | no |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP2_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| CIB1_HUMAN | [view interactions] | High throughput | no | no |
| NELFD_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| UBP3_HUMAN | [view interactions] | High throughput | no | no |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| MAMC2_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN1_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| SLBP_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| GFRP_HUMAN | [view interactions] | High throughput | no | no |
| NF2IP_HUMAN | [view interactions] | High throughput | no | no |
| EMIL1_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| CMTR1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| 4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4EBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3D_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3K_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| ANGE1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| IFT22_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC26_HUMAN | [view interactions] | High throughput | no | yes |
| CE350_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CND2_HUMAN | [view interactions] | High throughput | no | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP19_HUMAN | [view interactions] | High throughput | no | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| TOP2A_HUMAN | [view interactions] | High throughput | no | no |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS2_HUMAN | [view interactions] | High throughput | no | yes |
| MED28_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| RM32_HUMAN | [view interactions] | High throughput | no | yes |
| PTTG1_HUMAN | [view interactions] | High throughput | no | no |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAF2_HUMAN | [view interactions] | High throughput | no | no |
| XRN2_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| ZFYV9_HUMAN | [view interactions] | High throughput | no | yes |
| RAB31_HUMAN | [view interactions] | High throughput | no | yes |
| GLPK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPU_HUMAN | [view interactions] | High throughput | no | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| MCA3_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSB8_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP1_HUMAN | [view interactions] | High throughput | no | no |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUM3_HUMAN | [view interactions] | High throughput | no | yes |
| NAT10_HUMAN | [view interactions] | High throughput | no | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| PUS7_HUMAN | [view interactions] | High throughput | no | yes |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
| CLCN2_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTREX_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| SGTB_HUMAN | [view interactions] | High throughput | no | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPOE1_HUMAN | [view interactions] | High throughput | no | no |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| TB182_HUMAN | [view interactions] | High throughput | no | yes |
| RM09_HUMAN | [view interactions] | High throughput | no | yes |
| AGO2_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| ARP5_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DICER_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| Z3H7A_HUMAN | [view interactions] | High throughput | no | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| YLPM1_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HG2A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX60_HUMAN | [view interactions] | High throughput | no | no |
| GCH1_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAF1B_HUMAN | [view interactions] | High throughput | no | no |
| FOXB1_HUMAN | [view interactions] | High throughput | no | no |
| FOXL1_HUMAN | [view interactions] | High throughput | no | no |
| NBEL2_HUMAN | [view interactions] | High throughput | no | no |
| EF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF2A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF4H_HUMAN | [view interactions] | Computational | no | yes |
| RS8_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RIR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF2G_HUMAN | [view interactions] | Computational | no | yes |
| PAIP1_HUMAN | [view interactions] | Computational | no | yes |
| RS14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RENT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS15_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNOT3_HUMAN | [view interactions] | Computational | no | yes |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| RS24_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| 4EBP3_HUMAN | [view interactions] | Computational | no | yes |
| RS26_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NGDN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF2P_HUMAN | [view interactions] | Computational | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CNOT9_HUMAN | [view interactions] | Computational | no | yes |
| RL13A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNO6L_HUMAN | [view interactions] | Computational | no | no |
| PABP3_HUMAN | [view interactions] | Computational | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CASP1_HUMAN | [view interactions] | Computational | no | yes |
| XRN1_HUMAN | [view interactions] | Computational | no | yes |
| CNO11_HUMAN | [view interactions] | Computational | no | yes |
| CASP8_HUMAN | [view interactions] | Computational | no | yes |
| SMG5_HUMAN | [view interactions] | Computational | no | no |
| CNOT4_HUMAN | [view interactions] | Computational | no | yes |
| RS12_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNO10_HUMAN | [view interactions] | Computational | no | yes |
| PAN2_HUMAN | [view interactions] | Computational | no | no |
| CASP9_HUMAN | [view interactions] | Computational | no | yes |
| CNOT7_HUMAN | [view interactions] | Computational | no | no |
| CASP2_HUMAN | [view interactions] | Computational | no | yes |
| RS10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNOT6_HUMAN | [view interactions] | Computational | no | yes |
| RS30_HUMAN | [view interactions] | Computational | no | yes |
| RACK1_HUMAN | [view interactions] | Computational | no | yes |
| SMG7_HUMAN | [view interactions] | Computational | no | no |
| UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DDX10_HUMAN | [view interactions] | Computational | no | yes |
| ATP7A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF1AX_HUMAN | [view interactions] | Computational | no | yes |
| RS15A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS21_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIR2_HUMAN | [view interactions] | Computational | no | no |
| CASP4_HUMAN | [view interactions] | Computational | no | yes |
| PRS6B_HUMAN | [view interactions] | Computational | no | yes |
| RSSA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS29_HUMAN | [view interactions] | Computational | no | yes |
| PAN3_HUMAN | [view interactions] | Computational | no | yes |
| RS20_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CASP5_HUMAN | [view interactions] | Computational | no | no |
| I4E1B_HUMAN | [view interactions] | Computational | no | no |
| RS13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EST1A_HUMAN | [view interactions] | Computational | no | yes |
| RS23_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS18_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TIA1_HUMAN | [view interactions] | Computational | no | no |
| CASPA_HUMAN | [view interactions] | Computational | no | yes |
| RS28_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MI4GD_HUMAN | [view interactions] | Computational | no | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LS14A_HUMAN | [view interactions] | Computational | no | yes |
| CNOT2_HUMAN | [view interactions] | Computational | no | yes |
| PAP1L_HUMAN | [view interactions] | Computational | no | no |
| CNOT1_HUMAN | [view interactions] | Computational | no | yes |
| CASP6_HUMAN | [view interactions] | Computational | no | no |
| SH2D3_HUMAN | [view interactions] | Computational | no | no |
| IF4E3_HUMAN | [view interactions] | Computational | no | no |
| TUT7_HUMAN | [view interactions] | Computational | no | yes |
| PARN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PTBP2_HUMAN | [view interactions] | Computational | no | no |
| IF2B_HUMAN | [view interactions] | Computational | no | yes |
| HSPB3_HUMAN | [view interactions] | Computational | no | no |
| CNOT8_HUMAN | [view interactions] | Computational | no | yes |