KPCI_HUMAN
Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process at a very early step. In glioblastoma cells, may function downstream of phosphatidylinositol 3-kinase (PI(3)K) and PDPK1 in the promotion of cell survival by phosphorylating and inhibiting the pro-apoptotic factor BAD. Can form a protein complex in non-small cell lung cancer (NSCLC) cells with PARD6A and ECT2 and regulate ECT2 oncogenic activity by phosphorylation, which in turn promotes transformed growth and invasion. In response to nerve growth factor (NGF), acts downstream of SRC to phosphorylate and activate IRAK1, allowing the subsequent activation of NF-kappa-B and neuronal cell survival. Functions in the organization of the apical domain in epithelial cells by phosphorylating EZR. This step is crucial for activation and normal distribution of EZR at the early stages of intestinal epithelial cell differentiation. Forms a protein complex with LLGL1 and PARD6B independently of PARD3 to regulate epithelial cell polarity. Plays a role in microtubule dynamics in the early secretory pathway through interaction with RAB2A and GAPDH and recruitment to vesicular tubular clusters (VTCs). In human coronary artery endothelial cells (HCAEC), is activated by saturated fatty acids and mediates lipid-induced apoptosis. Involved in early synaptic long term potentiation phase in CA1 hippocampal cells and short term memory formation . [View more on UniProt]
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No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001635 | DOC_AGCK_PIF_2 | DOC | 579 | 584 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in KPCI_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 42.1569 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 41.1765 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 39.2157 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 25.4902 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 24.5098 | 5 | yes |
GO:0019900 | kinase binding | 24.5098 | 4 | no |
GO:0019901 | protein kinase binding | 23.5294 | 5 | no |
GO:0005524 | ATP binding | 22.5490 | 5 | yes |
GO:0016462 | pyrophosphatase activity | 22.5490 | 5 | no |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 22.5490 | 4 | no |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 22.5490 | 6 | no |
GO:0003723 | RNA binding | 21.5686 | 4 | no |
GO:0044389 | ubiquitin-like protein ligase binding | 20.5882 | 4 | no |
GO:0016301 | kinase activity | 15.6863 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 15.6863 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 14.7059 | 4 | yes |
GO:0046872 | metal ion binding | 13.7255 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 9.8039 | 4 | yes |
GO:0106310 | protein serine kinase activity | 8.8235 | 4 | yes |
GO:0004697 | protein kinase C activity | 3.9216 | 5 | yes |
GO:0004698 | calcium-dependent protein kinase C activity | 3.9216 | 6 | yes |
GO:0009931 | calcium-dependent protein serine/threonine kinase activity | 3.9216 | 5 | yes |
GO:0010857 | calcium-dependent protein kinase activity | 3.9216 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in KPCI_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 70.5882 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 61.7647 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 61.7647 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 60.7843 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 60.7843 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 60.7843 | 4 | yes |
GO:0010646 | regulation of cell communication | 57.8431 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 52.9412 | 4 | no |
GO:0009966 | regulation of signal transduction | 49.0196 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 48.0392 | 5 | no |
GO:0051128 | regulation of cellular component organization | 47.0588 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 46.0784 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 45.0980 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 44.1176 | 5 | no |
GO:0010468 | regulation of gene expression | 42.1569 | 5 | yes |
GO:0010941 | regulation of cell death | 41.1765 | 4 | yes |
GO:0006996 | organelle organization | 40.1961 | 4 | yes |
GO:0043067 | regulation of programmed cell death | 38.2353 | 5 | yes |
GO:0042981 | regulation of apoptotic process | 37.2549 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 37.2549 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 36.2745 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 36.2745 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 36.2745 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 36.2745 | 5 | no |
GO:0010647 | positive regulation of cell communication | 35.2941 | 5 | yes |
GO:0023056 | positive regulation of signaling | 35.2941 | 4 | yes |
GO:0042127 | regulation of cell population proliferation | 35.2941 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 35.2941 | 5 | no |
GO:0031399 | regulation of protein modification process | 35.2941 | 6 | no |
GO:0008104 | protein localization | 34.3137 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.3137 | 5 | yes |
GO:0051049 | regulation of transport | 34.3137 | 4 | yes |
GO:0071310 | cellular response to organic substance | 34.3137 | 4 | yes |
GO:0022607 | cellular component assembly | 34.3137 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 34.3137 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 33.3333 | 5 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 32.3529 | 5 | no |
GO:0032880 | regulation of protein localization | 31.3725 | 5 | yes |
GO:0060341 | regulation of cellular localization | 31.3725 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 30.3922 | 4 | yes |
GO:0051094 | positive regulation of developmental process | 30.3922 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 30.3922 | 5 | no |
GO:0051130 | positive regulation of cellular component organization | 29.4118 | 5 | yes |
GO:0051252 | regulation of RNA metabolic process | 29.4118 | 5 | yes |
GO:0060548 | negative regulation of cell death | 29.4118 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 29.4118 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 29.4118 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 28.4314 | 6 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 28.4314 | 4 | yes |
GO:0071702 | organic substance transport | 28.4314 | 4 | yes |
GO:1903506 | regulation of nucleic acid-templated transcription | 28.4314 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 28.4314 | 6 | yes |
GO:0010648 | negative regulation of cell communication | 28.4314 | 5 | no |
GO:0023057 | negative regulation of signaling | 28.4314 | 4 | no |
GO:0043085 | positive regulation of catalytic activity | 28.4314 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 27.4510 | 4 | yes |
GO:0071705 | nitrogen compound transport | 27.4510 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 27.4510 | 4 | no |
GO:0042325 | regulation of phosphorylation | 27.4510 | 7 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 27.4510 | 6 | no |
GO:0033043 | regulation of organelle organization | 27.4510 | 5 | no |
GO:0036211 | protein modification process | 26.4706 | 4 | yes |
GO:0043069 | negative regulation of programmed cell death | 26.4706 | 6 | yes |
GO:0043412 | macromolecule modification | 26.4706 | 4 | yes |
GO:0051336 | regulation of hydrolase activity | 26.4706 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 25.4902 | 7 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 25.4902 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 25.4902 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 25.4902 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 25.4902 | 6 | no |
GO:0008284 | positive regulation of cell population proliferation | 24.5098 | 5 | yes |
GO:0010243 | response to organonitrogen compound | 24.5098 | 4 | yes |
GO:0009894 | regulation of catabolic process | 24.5098 | 4 | no |
GO:0009968 | negative regulation of signal transduction | 24.5098 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 24.5098 | 7 | no |
GO:0015031 | protein transport | 23.5294 | 4 | yes |
GO:0045597 | positive regulation of cell differentiation | 23.5294 | 5 | yes |
GO:2000026 | regulation of multicellular organismal development | 23.5294 | 4 | yes |
GO:0051338 | regulation of transferase activity | 23.5294 | 4 | no |
GO:0031344 | regulation of cell projection organization | 22.5490 | 5 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.5490 | 6 | yes |
GO:0030030 | cell projection organization | 22.5490 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 22.5490 | 6 | no |
GO:0010628 | positive regulation of gene expression | 22.5490 | 6 | no |
GO:0031401 | positive regulation of protein modification process | 22.5490 | 7 | no |
GO:0042327 | positive regulation of phosphorylation | 22.5490 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 22.5490 | 7 | no |
GO:0080134 | regulation of response to stress | 22.5490 | 4 | no |
GO:0007010 | cytoskeleton organization | 21.5686 | 5 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.5686 | 6 | no |
GO:2000145 | regulation of cell motility | 21.5686 | 4 | no |
GO:0043549 | regulation of kinase activity | 21.5686 | 5 | no |
GO:0016310 | phosphorylation | 20.5882 | 5 | yes |
GO:1903829 | positive regulation of protein localization | 20.5882 | 5 | yes |
GO:0043933 | protein-containing complex organization | 20.5882 | 4 | no |
GO:0030334 | regulation of cell migration | 20.5882 | 5 | no |
GO:0030155 | regulation of cell adhesion | 20.5882 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 20.5882 | 5 | no |
GO:0010942 | positive regulation of cell death | 19.6078 | 5 | yes |
GO:0051050 | positive regulation of transport | 19.6078 | 4 | yes |
GO:0060284 | regulation of cell development | 19.6078 | 5 | yes |
GO:1901699 | cellular response to nitrogen compound | 18.6275 | 4 | yes |
GO:0006468 | protein phosphorylation | 17.6471 | 5 | yes |
GO:0006886 | intracellular protein transport | 17.6471 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 17.6471 | 4 | yes |
GO:0043065 | positive regulation of apoptotic process | 17.6471 | 7 | yes |
GO:0043068 | positive regulation of programmed cell death | 17.6471 | 6 | yes |
GO:0061024 | membrane organization | 17.6471 | 4 | yes |
GO:0071417 | cellular response to organonitrogen compound | 17.6471 | 4 | yes |
GO:0031346 | positive regulation of cell projection organization | 15.6863 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 14.7059 | 7 | yes |
GO:0034330 | cell junction organization | 14.7059 | 4 | yes |
GO:0010720 | positive regulation of cell development | 13.7255 | 6 | yes |
GO:0051960 | regulation of nervous system development | 13.7255 | 5 | yes |
GO:0097435 | supramolecular fiber organization | 13.7255 | 4 | yes |
GO:1901214 | regulation of neuron death | 13.7255 | 5 | yes |
GO:0034097 | response to cytokine | 12.7451 | 4 | yes |
GO:0050767 | regulation of neurogenesis | 12.7451 | 6 | yes |
GO:0018193 | peptidyl-amino acid modification | 11.7647 | 5 | yes |
GO:0032870 | cellular response to hormone stimulus | 11.7647 | 4 | yes |
GO:0051091 | positive regulation of DNA-binding transcription factor activity | 11.7647 | 4 | yes |
GO:0007015 | actin filament organization | 10.7843 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 10.7843 | 4 | yes |
GO:0043523 | regulation of neuron apoptotic process | 10.7843 | 6 | yes |
GO:0045216 | cell-cell junction organization | 10.7843 | 5 | yes |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 10.7843 | 5 | yes |
GO:1901652 | response to peptide | 10.7843 | 4 | yes |
GO:1905475 | regulation of protein localization to membrane | 10.7843 | 6 | yes |
GO:0072657 | protein localization to membrane | 9.8039 | 4 | yes |
GO:1901653 | cellular response to peptide | 9.8039 | 5 | yes |
GO:0006605 | protein targeting | 8.8235 | 5 | yes |
GO:0010976 | positive regulation of neuron projection development | 8.8235 | 7 | yes |
GO:1901215 | negative regulation of neuron death | 8.8235 | 6 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 8.8235 | 6 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 7.8431 | 6 | yes |
GO:0018209 | peptidyl-serine modification | 7.8431 | 6 | yes |
GO:0051962 | positive regulation of nervous system development | 7.8431 | 5 | yes |
GO:0043434 | response to peptide hormone | 6.8627 | 4 | yes |
GO:0043524 | negative regulation of neuron apoptotic process | 6.8627 | 7 | yes |
GO:0050769 | positive regulation of neurogenesis | 6.8627 | 6 | yes |
GO:0071375 | cellular response to peptide hormone stimulus | 6.8627 | 5 | yes |
GO:1905477 | positive regulation of protein localization to membrane | 6.8627 | 6 | yes |
GO:0032868 | response to insulin | 5.8824 | 5 | yes |
GO:0032869 | cellular response to insulin stimulus | 5.8824 | 6 | yes |
GO:0035088 | establishment or maintenance of apical/basal cell polarity | 5.8824 | 4 | yes |
GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 5.8824 | 5 | yes |
GO:0046903 | secretion | 5.8824 | 4 | yes |
GO:0048666 | neuron development | 5.8824 | 4 | yes |
GO:0070555 | response to interleukin-1 | 5.8824 | 5 | yes |
GO:1903076 | regulation of protein localization to plasma membrane | 5.8824 | 7 | yes |
GO:0034764 | positive regulation of transmembrane transport | 4.9020 | 5 | yes |
GO:0090150 | establishment of protein localization to membrane | 4.9020 | 4 | yes |
GO:1903078 | positive regulation of protein localization to plasma membrane | 4.9020 | 7 | yes |
GO:1904035 | regulation of epithelial cell apoptotic process | 4.9020 | 7 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 4.9020 | 6 | yes |
GO:0008593 | regulation of Notch signaling pathway | 3.9216 | 5 | yes |
GO:0014013 | regulation of gliogenesis | 3.9216 | 7 | yes |
GO:0035089 | establishment of apical/basal cell polarity | 3.9216 | 5 | yes |
GO:0061162 | establishment of monopolar cell polarity | 3.9216 | 4 | yes |
GO:2000351 | regulation of endothelial cell apoptotic process | 3.9216 | 8 | yes |
GO:0006612 | protein targeting to membrane | 2.9412 | 5 | yes |
GO:0016050 | vesicle organization | 2.9412 | 5 | yes |
GO:0042461 | photoreceptor cell development | 2.9412 | 5 | yes |
GO:0042462 | eye photoreceptor cell development | 2.9412 | 6 | yes |
GO:0045747 | positive regulation of Notch signaling pathway | 2.9412 | 6 | yes |
GO:1904037 | positive regulation of epithelial cell apoptotic process | 2.9412 | 8 | yes |
GO:0006900 | vesicle budding from membrane | 1.9608 | 5 | yes |
GO:0010827 | regulation of glucose transmembrane transport | 1.9608 | 5 | yes |
GO:0010828 | positive regulation of glucose transmembrane transport | 1.9608 | 6 | yes |
GO:0014015 | positive regulation of gliogenesis | 1.9608 | 7 | yes |
GO:0034350 | regulation of glial cell apoptotic process | 1.9608 | 7 | yes |
GO:0034351 | negative regulation of glial cell apoptotic process | 1.9608 | 8 | yes |
GO:0046324 | regulation of glucose import | 1.9608 | 6 | yes |
GO:0046326 | positive regulation of glucose import | 1.9608 | 7 | yes |
GO:0048194 | Golgi vesicle budding | 1.9608 | 6 | yes |
GO:0060251 | regulation of glial cell proliferation | 1.9608 | 5 | yes |
GO:0060252 | positive regulation of glial cell proliferation | 1.9608 | 6 | yes |
GO:2000353 | positive regulation of endothelial cell apoptotic process | 1.9608 | 9 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in KPCI_HUMAN |
---|---|---|---|---|
DOID:331 | central nervous system disease | 2.9412 | 3 | no |
DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.9608 | 7 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 1.9608 | 6 | no |
DOID:440 | neuromuscular disease | 1.9608 | 5 | no |
DOID:574 | peripheral nervous system disease | 1.9608 | 3 | no |
DOID:870 | neuropathy | 1.9608 | 4 | no |
DOID:1289 | neurodegenerative disease | 1.9608 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ASPP2_HUMAN | [view interactions] | Low throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CDK7_HUMAN | [view interactions] | Low throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DIDO1_HUMAN | [view interactions] | Low throughput | no | yes |
FCG3A_HUMAN | [view interactions] | Low throughput | no | no |
ZO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PAR6A_HUMAN | [view interactions] | Low throughput | no | yes |
PAR6B_HUMAN | [view interactions] | Low throughput | no | no |
RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
MARK4_HUMAN | [view interactions] | Low throughput | no | yes |
SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GLI1_HUMAN | [view interactions] | Low throughput | no | no |
PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ELF3_HUMAN | [view interactions] | Low throughput | no | no |
EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MTSS1_HUMAN | [view interactions] | Low throughput | no | no |
SOX2_HUMAN | [view interactions] | Low throughput | no | yes |
SMG1_HUMAN | [view interactions] | Low throughput | no | yes |
FRS2_HUMAN | [view interactions] | Low throughput | no | no |
ADAP1_HUMAN | [view interactions] | Low throughput | no | yes |
RAB4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SFPQ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
GAB1_HUMAN | [view interactions] | Low throughput | no | yes |
CCNT1_HUMAN | [view interactions] | Low throughput | no | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAFB_HUMAN | [view interactions] | High throughput | no | yes |
KDF1_HUMAN | [view interactions] | High throughput | no | yes |
DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
C2C4A_HUMAN | [view interactions] | High throughput | no | no |
ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPXN4_HUMAN | [view interactions] | High throughput | no | no |
IL17F_HUMAN | [view interactions] | High throughput | no | no |
S66AL_HUMAN | [view interactions] | High throughput | no | no |
GNLY_HUMAN | [view interactions] | High throughput | no | no |
EP3B_HUMAN | [view interactions] | High throughput | no | no |
LRC17_HUMAN | [view interactions] | High throughput | no | no |
IL7RA_HUMAN | [view interactions] | High throughput | no | no |
RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRC2_HUMAN | [view interactions] | High throughput | no | no |
GREM2_HUMAN | [view interactions] | High throughput | no | no |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
RHOU_HUMAN | [view interactions] | High throughput | no | no |
RHOV_HUMAN | [view interactions] | High throughput | no | no |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
RND1_HUMAN | [view interactions] | High throughput | no | no |
RND3_HUMAN | [view interactions] | High throughput | no | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATG7_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
KIF23_HUMAN | [view interactions] | High throughput | no | yes |
PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
UBP20_HUMAN | [view interactions] | High throughput | no | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
OPTN_HUMAN | [view interactions] | High throughput | no | yes |
PAR6G_HUMAN | [view interactions] | High throughput | no | no |
CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
FABP4_HUMAN | [view interactions] | High throughput | no | no |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
T22D1_HUMAN | [view interactions] | High throughput | no | no |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
TTHY_HUMAN | [view interactions] | High throughput | no | no |
CXD3_HUMAN | [view interactions] | High throughput | no | no |
LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PXMP2_HUMAN | [view interactions] | High throughput | no | no |
DPP4_HUMAN | [view interactions] | High throughput | no | no |
MYO10_HUMAN | [view interactions] | High throughput | no | no |
NBR1_HUMAN | [view interactions] | High throughput | no | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
L2GL2_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
L2GL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PNMA1_HUMAN | [view interactions] | High throughput | no | yes |
SLX4_HUMAN | [view interactions] | High throughput | no | yes |
UBP21_HUMAN | [view interactions] | High throughput | no | no |
MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRAP_HUMAN | [view interactions] | High throughput | no | no |
GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
HAKAI_HUMAN | [view interactions] | High throughput | no | yes |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LAMA1_HUMAN | [view interactions] | High throughput | no | no |
AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PYGB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
XRCC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CENPV_HUMAN | [view interactions] | High throughput | no | yes |
LSG1_HUMAN | [view interactions] | High throughput | no | yes |
KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
RT18B_HUMAN | [view interactions] | High throughput | no | yes |
MBD4_HUMAN | [view interactions] | High throughput | no | yes |
AT5EL_HUMAN | [view interactions] | High throughput | no | no |
TM160_HUMAN | [view interactions] | High throughput | no | no |
ZNF3_HUMAN | [view interactions] | High throughput | no | yes |
TM165_HUMAN | [view interactions] | High throughput | no | yes |
TIM23_HUMAN | [view interactions] | High throughput | no | yes |
RM11_HUMAN | [view interactions] | High throughput | no | yes |
4ET_HUMAN | [view interactions] | High throughput | no | yes |
MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
ZN609_HUMAN | [view interactions] | High throughput | no | yes |
LA_HUMAN | [view interactions] | High throughput | no | yes |
KERA_HUMAN | [view interactions] | High throughput | no | no |
KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
GP156_HUMAN | [view interactions] | High throughput | no | no |
FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
RPOM_HUMAN | [view interactions] | High throughput | no | yes |
DPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL1D1_HUMAN | [view interactions] | High throughput | no | yes |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD44_HUMAN | [view interactions] | High throughput | no | yes |
HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP77_HUMAN | [view interactions] | High throughput | no | no |
FBRL_HUMAN | [view interactions] | High throughput | no | yes |
KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10A7_HUMAN | [view interactions] | High throughput | no | no |
S1A7A_HUMAN | [view interactions] | High throughput | no | no |
DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RT29_HUMAN | [view interactions] | High throughput | no | yes |
RM12_HUMAN | [view interactions] | High throughput | no | yes |
CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK23_HUMAN | [view interactions] | High throughput | no | no |
RT22_HUMAN | [view interactions] | High throughput | no | yes |
RT25_HUMAN | [view interactions] | High throughput | no | yes |
RT10_HUMAN | [view interactions] | High throughput | no | yes |
RT35_HUMAN | [view interactions] | High throughput | no | yes |
RT34_HUMAN | [view interactions] | High throughput | no | yes |
RT09_HUMAN | [view interactions] | High throughput | no | yes |
MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LAT1_HUMAN | [view interactions] | High throughput | no | yes |
SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPH_HUMAN | [view interactions] | High throughput | no | yes |
MOGS_HUMAN | [view interactions] | High throughput | no | yes |
RCN2_HUMAN | [view interactions] | High throughput | no | yes |
S35G1_HUMAN | [view interactions] | High throughput | no | no |
TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RM10_HUMAN | [view interactions] | High throughput | no | yes |
BRX1_HUMAN | [view interactions] | High throughput | no | no |
UBP7_HUMAN | [view interactions] | High throughput | no | yes |
RM53_HUMAN | [view interactions] | High throughput | no | yes |
ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCF25_HUMAN | [view interactions] | High throughput | no | yes |
MBB1A_HUMAN | [view interactions] | High throughput | no | yes |
TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ABHDA_HUMAN | [view interactions] | High throughput | no | yes |
DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
RT02_HUMAN | [view interactions] | High throughput | no | no |
RT18C_HUMAN | [view interactions] | High throughput | no | yes |
NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
TF3C5_HUMAN | [view interactions] | High throughput | no | yes |
HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
RT18A_HUMAN | [view interactions] | High throughput | no | yes |
RM28_HUMAN | [view interactions] | High throughput | no | yes |
DDX10_HUMAN | [view interactions] | High throughput | no | yes |
RM23_HUMAN | [view interactions] | High throughput | no | yes |
RM02_HUMAN | [view interactions] | High throughput | no | yes |
RM43_HUMAN | [view interactions] | High throughput | no | no |
PRP16_HUMAN | [view interactions] | High throughput | no | yes |
RM38_HUMAN | [view interactions] | High throughput | no | yes |
RM45_HUMAN | [view interactions] | High throughput | no | no |
RM47_HUMAN | [view interactions] | High throughput | no | yes |
RM39_HUMAN | [view interactions] | High throughput | no | yes |
RM15_HUMAN | [view interactions] | High throughput | no | yes |
CAMP3_HUMAN | [view interactions] | High throughput | no | no |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
CASP8_HUMAN | [view interactions] | High throughput | no | yes |
IL1AP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEMO_HUMAN | [view interactions] | High throughput | no | yes |
NACC1_HUMAN | [view interactions] | High throughput | no | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AMOT_HUMAN | [view interactions] | High throughput | no | no |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
CP135_HUMAN | [view interactions] | High throughput | no | no |
KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTMR4_HUMAN | [view interactions] | High throughput | no | no |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
EPHA5_HUMAN | [view interactions] | High throughput | no | no |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MEOX2_HUMAN | [view interactions] | High throughput | no | no |
DUS1_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHG17_HUMAN | [view interactions] | High throughput | no | no |
MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRX_HUMAN | [view interactions] | High throughput | no | no |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
RASF8_HUMAN | [view interactions] | High throughput | no | yes |
TM208_HUMAN | [view interactions] | High throughput | no | yes |
TPC13_HUMAN | [view interactions] | High throughput | no | yes |
GWL_HUMAN | [view interactions] | High throughput | no | yes |
ATP5E_HUMAN | [view interactions] | High throughput | no | no |
DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOL8_HUMAN | [view interactions] | High throughput | no | yes |
PRR3_HUMAN | [view interactions] | High throughput | no | no |
INT14_HUMAN | [view interactions] | High throughput | no | yes |
FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FARP2_HUMAN | [view interactions] | High throughput | no | yes |
ARHGG_HUMAN | [view interactions] | High throughput | no | yes |
PDGFD_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
KIBRA_HUMAN | [view interactions] | High throughput | no | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRD7_HUMAN | [view interactions] | High throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
E41LB_HUMAN | [view interactions] | Computational | no | yes |
VAMP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RIPK2_HUMAN | [view interactions] | Computational | no | yes |
INS_HUMAN | [view interactions] | Computational | no | no |
PAR3_HUMAN | [view interactions] | Computational | no | no |
INSR_HUMAN | [view interactions] | Computational | no | yes |
TNR1A_HUMAN | [view interactions] | Computational | no | yes |
RAP1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
AMOL1_HUMAN | [view interactions] | Computational | no | no |
LCAP_HUMAN | [view interactions] | Computational | no | yes |
TRAF2_HUMAN | [view interactions] | Computational | no | yes |
GRB14_HUMAN | [view interactions] | Computational | no | yes |
TNR16_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KIRR1_HUMAN | [view interactions] | Computational | no | no |
CIP4_HUMAN | [view interactions] | Computational | no | no |
RIPK1_HUMAN | [view interactions] | Computational | no | yes |
SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TNFA_HUMAN | [view interactions] | Computational | no | no |
NUMBL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RB6I2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TRADD_HUMAN | [view interactions] | Computational | no | yes |
CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAP1B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
NUMB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TRAF6_HUMAN | [view interactions] | Computational | no | yes |
PAR3L_HUMAN | [view interactions] | Computational | no | yes |
NPHN_HUMAN | [view interactions] | Computational | no | no |
CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NFKB1_HUMAN | [view interactions] | Computational | no | yes |
STK11_HUMAN | [view interactions] | Computational | no | yes |
IRAK1_HUMAN | [view interactions] | Computational | no | yes |
CTNA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AMOL2_HUMAN | [view interactions] | Computational | no | no |
GLUT4_HUMAN | [view interactions] | Computational | no | no |
NGF_HUMAN | [view interactions] | Computational | no | no |