IPO5_HUMAN
Evidence for PS localization
Functions
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus . Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation . In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IPO5_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 38.0531 | 4 | yes |
| GO:0000166 | nucleotide binding | 25.6637 | 4 | no |
| GO:0017076 | purine nucleotide binding | 25.6637 | 5 | no |
| GO:0043168 | anion binding | 25.6637 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 24.7788 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.7788 | 4 | no |
| GO:0043169 | cation binding | 23.8938 | 4 | no |
| GO:0046872 | metal ion binding | 23.8938 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 20.3540 | 6 | no |
| GO:0051020 | GTPase binding | 7.0796 | 4 | yes |
| GO:0031267 | small GTPase binding | 6.1947 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 4.4248 | 4 | yes |
| GO:0008139 | nuclear localization sequence binding | 3.5398 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IPO5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.7522 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 51.3274 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 48.6726 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 48.6726 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 41.5929 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 40.7080 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 40.7080 | 4 | no |
| GO:0010646 | regulation of cell communication | 40.7080 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 39.8230 | 5 | no |
| GO:0006996 | organelle organization | 39.8230 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.9381 | 5 | no |
| GO:0009966 | regulation of signal transduction | 38.9381 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.0531 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 37.1681 | 5 | yes |
| GO:0010468 | regulation of gene expression | 36.2832 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.5133 | 5 | no |
| GO:0008104 | protein localization | 31.8584 | 4 | yes |
| GO:0022607 | cellular component assembly | 31.8584 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.8584 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 30.9735 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 30.9735 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.2035 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 29.2035 | 5 | no |
| GO:0032880 | regulation of protein localization | 28.3186 | 5 | yes |
| GO:0051049 | regulation of transport | 28.3186 | 4 | yes |
| GO:0036211 | protein modification process | 28.3186 | 4 | no |
| GO:0043412 | macromolecule modification | 28.3186 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.4336 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.4336 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.4336 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.5487 | 5 | no |
| GO:0031399 | regulation of protein modification process | 25.6637 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 25.6637 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 25.6637 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.6637 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.7788 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.7788 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.7788 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.8938 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 23.8938 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.8938 | 6 | no |
| GO:0009894 | regulation of catabolic process | 23.8938 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.0088 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 23.0088 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 23.0088 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.0088 | 5 | no |
| GO:0023057 | negative regulation of signaling | 23.0088 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.0088 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.0088 | 4 | no |
| GO:0071702 | organic substance transport | 22.1239 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.1239 | 6 | no |
| GO:0071705 | nitrogen compound transport | 21.2389 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 21.2389 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 21.2389 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.2389 | 6 | no |
| GO:0071310 | cellular response to organic substance | 21.2389 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.2389 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 18.5841 | 7 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 18.5841 | 6 | yes |
| GO:0001932 | regulation of protein phosphorylation | 17.6991 | 7 | yes |
| GO:0015031 | protein transport | 17.6991 | 4 | yes |
| GO:0051050 | positive regulation of transport | 17.6991 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 17.6991 | 4 | yes |
| GO:0006886 | intracellular protein transport | 15.0442 | 4 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 15.0442 | 6 | yes |
| GO:0031400 | negative regulation of protein modification process | 15.0442 | 7 | yes |
| GO:0033365 | protein localization to organelle | 15.0442 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 15.0442 | 7 | yes |
| GO:0080134 | regulation of response to stress | 15.0442 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 14.1593 | 4 | yes |
| GO:0070201 | regulation of establishment of protein localization | 14.1593 | 6 | yes |
| GO:0032386 | regulation of intracellular transport | 13.2743 | 5 | yes |
| GO:0043086 | negative regulation of catalytic activity | 12.3894 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 12.3894 | 5 | yes |
| GO:0006913 | nucleocytoplasmic transport | 11.5044 | 5 | yes |
| GO:0042326 | negative regulation of phosphorylation | 11.5044 | 8 | yes |
| GO:0051169 | nuclear transport | 11.5044 | 4 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 10.6195 | 8 | yes |
| GO:0045859 | regulation of protein kinase activity | 10.6195 | 6 | yes |
| GO:0051223 | regulation of protein transport | 10.6195 | 5 | yes |
| GO:0051348 | negative regulation of transferase activity | 10.6195 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 9.7345 | 4 | yes |
| GO:0032388 | positive regulation of intracellular transport | 9.7345 | 5 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 9.7345 | 6 | yes |
| GO:0033673 | negative regulation of kinase activity | 8.8496 | 6 | yes |
| GO:0072594 | establishment of protein localization to organelle | 8.8496 | 4 | yes |
| GO:0033157 | regulation of intracellular protein transport | 7.9646 | 6 | yes |
| GO:0034504 | protein localization to nucleus | 7.9646 | 6 | yes |
| GO:0050776 | regulation of immune response | 7.9646 | 4 | yes |
| GO:0006469 | negative regulation of protein kinase activity | 7.0796 | 7 | yes |
| GO:0006606 | protein import into nucleus | 7.0796 | 5 | yes |
| GO:0051170 | import into nucleus | 7.0796 | 6 | yes |
| GO:0051222 | positive regulation of protein transport | 7.0796 | 5 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 7.0796 | 7 | yes |
| GO:0002684 | positive regulation of immune system process | 6.1947 | 4 | yes |
| GO:0031347 | regulation of defense response | 6.1947 | 5 | yes |
| GO:0046822 | regulation of nucleocytoplasmic transport | 6.1947 | 6 | yes |
| GO:1900180 | regulation of protein localization to nucleus | 6.1947 | 6 | yes |
| GO:0090316 | positive regulation of intracellular protein transport | 5.3097 | 6 | yes |
| GO:1900182 | positive regulation of protein localization to nucleus | 5.3097 | 6 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 4.4248 | 4 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 4.4248 | 5 | yes |
| GO:0045088 | regulation of innate immune response | 4.4248 | 5 | yes |
| GO:0046824 | positive regulation of nucleocytoplasmic transport | 4.4248 | 6 | yes |
| GO:0050778 | positive regulation of immune response | 4.4248 | 5 | yes |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 4.4248 | 8 | yes |
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 3.5398 | 6 | yes |
| GO:0031349 | positive regulation of defense response | 3.5398 | 5 | yes |
| GO:0045786 | negative regulation of cell cycle | 3.5398 | 5 | yes |
| GO:1904029 | regulation of cyclin-dependent protein kinase activity | 3.5398 | 5 | yes |
| GO:0002833 | positive regulation of response to biotic stimulus | 2.6549 | 5 | yes |
| GO:0006607 | NLS-bearing protein import into nucleus | 2.6549 | 6 | yes |
| GO:0043200 | response to amino acid | 2.6549 | 4 | yes |
| GO:0045089 | positive regulation of innate immune response | 2.6549 | 6 | yes |
| GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 2.6549 | 6 | yes |
| GO:1904030 | negative regulation of cyclin-dependent protein kinase activity | 2.6549 | 6 | yes |
| GO:0002221 | pattern recognition receptor signaling pathway | 1.7699 | 5 | yes |
| GO:0002758 | innate immune response-activating signaling pathway | 1.7699 | 4 | yes |
| GO:0006610 | ribosomal protein import into nucleus | 1.7699 | 6 | yes |
| GO:0042306 | regulation of protein import into nucleus | 1.7699 | 7 | yes |
| GO:0042307 | positive regulation of protein import into nucleus | 1.7699 | 7 | yes |
| GO:0071229 | cellular response to acid chemical | 1.7699 | 4 | yes |
| GO:0071230 | cellular response to amino acid stimulus | 1.7699 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NU214_HUMAN | [view interactions] | Low throughput | no | no |
| NU153_HUMAN | [view interactions] | Low throughput | no | yes |
| NOSIP_HUMAN | [view interactions] | Low throughput | no | yes |
| RL7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GASP3_HUMAN | [view interactions] | Low throughput | no | no |
| SRP19_HUMAN | [view interactions] | Low throughput | no | yes |
| RL23A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PELP1_HUMAN | [view interactions] | Low throughput | no | yes |
| MUC1_HUMAN | [view interactions] | Low throughput | no | no |
| RAG2_HUMAN | [view interactions] | Low throughput | no | no |
| IMA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LLPH_HUMAN | [view interactions] | High throughput | no | no |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SRFB1_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| DDX10_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBIS_HUMAN | [view interactions] | High throughput | no | no |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| NOM1_HUMAN | [view interactions] | High throughput | no | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| CRBG3_HUMAN | [view interactions] | High throughput | no | no |
| RPAC2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| KCTD9_HUMAN | [view interactions] | High throughput | no | no |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| WASP_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX33_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAF1D_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP50_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PR15A_HUMAN | [view interactions] | High throughput | no | yes |
| IPO4_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| HEXB_HUMAN | [view interactions] | High throughput | no | no |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| MCTS1_HUMAN | [view interactions] | High throughput | no | no |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| TFIP8_HUMAN | [view interactions] | High throughput | no | no |
| SPICE_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX56_HUMAN | [view interactions] | High throughput | no | yes |
| RHG29_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| IPO9_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| IMA6_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3C_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACD_HUMAN | [view interactions] | High throughput | no | no |
| SCAM3_HUMAN | [view interactions] | High throughput | no | no |
| H31_HUMAN | [view interactions] | High throughput | no | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| M3K14_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAB2_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| RS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIH_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| OGA_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| ANM3_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| PSD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| CP131_HUMAN | [view interactions] | High throughput | no | no |
| RO60_HUMAN | [view interactions] | High throughput | no | yes |
| NH2L1_HUMAN | [view interactions] | High throughput | no | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TINF2_HUMAN | [view interactions] | High throughput | no | no |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGR1_HUMAN | [view interactions] | High throughput | no | no |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| PSB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRC2B_HUMAN | [view interactions] | High throughput | no | no |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS10_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPCE_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| RN146_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| NBN_HUMAN | [view interactions] | High throughput | no | yes |
| SPSY_HUMAN | [view interactions] | High throughput | no | no |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAS1L_HUMAN | [view interactions] | High throughput | no | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF3_HUMAN | [view interactions] | High throughput | no | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| ASB15_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ZMYM3_HUMAN | [view interactions] | High throughput | no | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| FLNC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| CND1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| MPIP1_HUMAN | [view interactions] | High throughput | no | no |
| CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR3_HUMAN | [view interactions] | High throughput | no | no |
| HEAT6_HUMAN | [view interactions] | High throughput | no | no |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP2_HUMAN | [view interactions] | High throughput | no | yes |
| RM34_HUMAN | [view interactions] | High throughput | no | yes |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| NOL9_HUMAN | [view interactions] | High throughput | no | no |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| NOL7_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI5_HUMAN | [view interactions] | High throughput | no | yes |
| RM35_HUMAN | [view interactions] | High throughput | no | no |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAP26_HUMAN | [view interactions] | High throughput | no | yes |
| RAD50_HUMAN | [view interactions] | High throughput | no | yes |
| ZN414_HUMAN | [view interactions] | High throughput | no | yes |
| PAWR_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| TOPK_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| TSNAX_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| MCMBP_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LS14B_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| PAR6B_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| TBC23_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| ASF1B_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| ASH2L_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | High throughput | no | no |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP1_HUMAN | [view interactions] | High throughput | no | no |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| S23IP_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| CHCH1_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD1_HUMAN | [view interactions] | High throughput | no | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| MGDP1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPA_HUMAN | [view interactions] | High throughput | no | no |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| ZN330_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| H33_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| DET1_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRM2_HUMAN | [view interactions] | High throughput | no | no |
| RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AVPI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMTA1_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| NOP16_HUMAN | [view interactions] | High throughput | no | yes |
| S27A2_HUMAN | [view interactions] | High throughput | no | no |
| NOC3L_HUMAN | [view interactions] | High throughput | no | no |
| NOC4L_HUMAN | [view interactions] | High throughput | no | no |
| WDR18_HUMAN | [view interactions] | High throughput | no | yes |
| RM20_HUMAN | [view interactions] | High throughput | no | yes |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBG_HUMAN | [view interactions] | High throughput | no | no |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| MACIR_HUMAN | [view interactions] | High throughput | no | no |
| MIRO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNBP6_HUMAN | [view interactions] | High throughput | no | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| REXO4_HUMAN | [view interactions] | High throughput | no | yes |
| TEX10_HUMAN | [view interactions] | High throughput | no | no |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| NOP14_HUMAN | [view interactions] | High throughput | no | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| L10K_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| GNL3_HUMAN | [view interactions] | High throughput | no | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| PO2F1_HUMAN | [view interactions] | High throughput | no | yes |
| NFYA_HUMAN | [view interactions] | High throughput | no | yes |
| PWP1_HUMAN | [view interactions] | High throughput | no | no |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| CENPE_HUMAN | [view interactions] | High throughput | no | no |
| CEP78_HUMAN | [view interactions] | High throughput | no | yes |
| RL29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |