IPO5_HUMAN
Evidence for PS localization
Functions
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus . Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation . In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IPO5_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 38.8889 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 23.6111 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 23.6111 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.6111 | 4 | no |
| GO:0046872 | metal ion binding | 22.2222 | 4 | no |
| GO:0031267 | small GTPase binding | 9.7222 | 5 | yes |
| GO:0051020 | GTPase binding | 9.7222 | 4 | yes |
| GO:0005048 | signal sequence binding | 6.9444 | 4 | yes |
| GO:0008139 | nuclear localization sequence binding | 6.9444 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 6.9444 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IPO5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 56.9444 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 48.6111 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 47.2222 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 44.4444 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 41.6667 | 4 | no |
| GO:0010646 | regulation of cell communication | 40.2778 | 4 | no |
| GO:0006996 | organelle organization | 38.8889 | 4 | no |
| GO:0009966 | regulation of signal transduction | 38.8889 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.5000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 36.1111 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.1111 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 34.7222 | 4 | yes |
| GO:0051049 | regulation of transport | 33.3333 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 33.3333 | 5 | no |
| GO:0036211 | protein modification process | 31.9444 | 4 | no |
| GO:0043412 | macromolecule modification | 31.9444 | 4 | no |
| GO:0010468 | regulation of gene expression | 31.9444 | 5 | no |
| GO:0010941 | regulation of cell death | 31.9444 | 4 | no |
| GO:0008104 | protein localization | 31.9444 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.9444 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 30.5556 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 30.5556 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 29.1667 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 29.1667 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 29.1667 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 29.1667 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.7778 | 5 | yes |
| GO:0022607 | cellular component assembly | 27.7778 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 27.7778 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 27.7778 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 27.7778 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 26.3889 | 4 | no |
| GO:0033043 | regulation of organelle organization | 26.3889 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.3889 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.3889 | 6 | no |
| GO:0032880 | regulation of protein localization | 26.3889 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 25.0000 | 7 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 23.6111 | 6 | yes |
| GO:0071702 | organic substance transport | 23.6111 | 4 | yes |
| GO:0051050 | positive regulation of transport | 22.2222 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 22.2222 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 22.2222 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.2222 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.2222 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.2222 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.2222 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 22.2222 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.2222 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.2222 | 7 | yes |
| GO:0033365 | protein localization to organelle | 22.2222 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 20.8333 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 20.8333 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 19.4444 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 19.4444 | 5 | yes |
| GO:0015031 | protein transport | 19.4444 | 4 | yes |
| GO:0051223 | regulation of protein transport | 18.0556 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 18.0556 | 6 | yes |
| GO:0006886 | intracellular protein transport | 18.0556 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 18.0556 | 4 | yes |
| GO:0031400 | negative regulation of protein modification process | 18.0556 | 7 | yes |
| GO:0032386 | regulation of intracellular transport | 18.0556 | 5 | yes |
| GO:0043086 | negative regulation of catalytic activity | 18.0556 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 18.0556 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 16.6667 | 7 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 16.6667 | 6 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 15.2778 | 4 | yes |
| GO:0045859 | regulation of protein kinase activity | 15.2778 | 6 | yes |
| GO:0051169 | nuclear transport | 13.8889 | 4 | yes |
| GO:0051222 | positive regulation of protein transport | 13.8889 | 5 | yes |
| GO:0051348 | negative regulation of transferase activity | 13.8889 | 5 | yes |
| GO:0072594 | establishment of protein localization to organelle | 13.8889 | 4 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 13.8889 | 6 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 13.8889 | 8 | yes |
| GO:0006913 | nucleocytoplasmic transport | 13.8889 | 5 | yes |
| GO:0032388 | positive regulation of intracellular transport | 13.8889 | 5 | yes |
| GO:0033157 | regulation of intracellular protein transport | 13.8889 | 6 | yes |
| GO:0042326 | negative regulation of phosphorylation | 13.8889 | 8 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 12.5000 | 4 | yes |
| GO:1901699 | cellular response to nitrogen compound | 12.5000 | 4 | yes |
| GO:0034504 | protein localization to nucleus | 12.5000 | 6 | yes |
| GO:0051170 | import into nucleus | 11.1111 | 6 | yes |
| GO:0006606 | protein import into nucleus | 11.1111 | 5 | yes |
| GO:0033673 | negative regulation of kinase activity | 11.1111 | 6 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 9.7222 | 7 | yes |
| GO:0090316 | positive regulation of intracellular protein transport | 9.7222 | 6 | yes |
| GO:0006469 | negative regulation of protein kinase activity | 9.7222 | 7 | yes |
| GO:0046822 | regulation of nucleocytoplasmic transport | 8.3333 | 6 | yes |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 6.9444 | 8 | yes |
| GO:0046824 | positive regulation of nucleocytoplasmic transport | 5.5556 | 6 | yes |
| GO:1900180 | regulation of protein localization to nucleus | 5.5556 | 6 | yes |
| GO:1904029 | regulation of cyclin-dependent protein kinase activity | 5.5556 | 5 | yes |
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 5.5556 | 6 | yes |
| GO:0006607 | NLS-bearing protein import into nucleus | 5.5556 | 6 | yes |
| GO:0045786 | negative regulation of cell cycle | 5.5556 | 5 | yes |
| GO:1900182 | positive regulation of protein localization to nucleus | 4.1667 | 6 | yes |
| GO:1904030 | negative regulation of cyclin-dependent protein kinase activity | 4.1667 | 6 | yes |
| GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 4.1667 | 6 | yes |
| GO:0006610 | ribosomal protein import into nucleus | 2.7778 | 6 | yes |
| GO:0042306 | regulation of protein import into nucleus | 2.7778 | 7 | yes |
| GO:0042307 | positive regulation of protein import into nucleus | 2.7778 | 7 | yes |
| GO:0043200 | response to amino acid | 2.7778 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in IPO5_HUMAN |
|---|---|---|---|---|
| DOID:1289 | neurodegenerative disease | 2.7778 | 4 | no |
| DOID:331 | central nervous system disease | 2.7778 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RL7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BHLH9_HUMAN | [view interactions] | Low throughput | no | no |
| SRP19_HUMAN | [view interactions] | Low throughput | no | yes |
| RL23A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PELP1_HUMAN | [view interactions] | Low throughput | no | yes |
| MUC1_HUMAN | [view interactions] | Low throughput | no | no |
| RAG2_HUMAN | [view interactions] | Low throughput | no | no |
| IMA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
| NU214_HUMAN | [view interactions] | Low throughput | no | no |
| NU153_HUMAN | [view interactions] | Low throughput | no | yes |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| CHCH1_HUMAN | [view interactions] | High throughput | no | yes |
| SPICE_HUMAN | [view interactions] | High throughput | no | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| RHG29_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| CENPA_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3C_HUMAN | [view interactions] | High throughput | no | no |
| ZN330_HUMAN | [view interactions] | High throughput | no | yes |
| ACD_HUMAN | [view interactions] | High throughput | no | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| H31_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| M3K14_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| GAB2_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| CP131_HUMAN | [view interactions] | High throughput | no | no |
| NH2L1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC1_HUMAN | [view interactions] | High throughput | no | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| TINF2_HUMAN | [view interactions] | High throughput | no | no |
| RPGR1_HUMAN | [view interactions] | High throughput | no | no |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2B_HUMAN | [view interactions] | High throughput | no | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS10_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| RN146_HUMAN | [view interactions] | High throughput | no | yes |
| NBN_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| LAS1L_HUMAN | [view interactions] | High throughput | no | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ASB15_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MPIP1_HUMAN | [view interactions] | High throughput | no | no |
| MTMR3_HUMAN | [view interactions] | High throughput | no | no |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| RM34_HUMAN | [view interactions] | High throughput | no | yes |
| NOL9_HUMAN | [view interactions] | High throughput | no | no |
| NOL7_HUMAN | [view interactions] | High throughput | no | yes |
| RM35_HUMAN | [view interactions] | High throughput | no | no |
| TAP26_HUMAN | [view interactions] | High throughput | no | yes |
| ZN414_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD1_HUMAN | [view interactions] | High throughput | no | no |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| MGDP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRM2_HUMAN | [view interactions] | High throughput | no | no |
| RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AVPI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMTA1_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| NOP16_HUMAN | [view interactions] | High throughput | no | yes |
| S27A2_HUMAN | [view interactions] | High throughput | no | no |
| NOC3L_HUMAN | [view interactions] | High throughput | no | no |
| NOC4L_HUMAN | [view interactions] | High throughput | no | no |
| WDR18_HUMAN | [view interactions] | High throughput | no | yes |
| RM20_HUMAN | [view interactions] | High throughput | no | yes |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBG_HUMAN | [view interactions] | High throughput | no | no |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| MACIR_HUMAN | [view interactions] | High throughput | no | no |
| MIRO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNBP6_HUMAN | [view interactions] | High throughput | no | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| REXO4_HUMAN | [view interactions] | High throughput | no | yes |
| TEX10_HUMAN | [view interactions] | High throughput | no | no |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| NOP14_HUMAN | [view interactions] | High throughput | no | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| L10K_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| GNL3_HUMAN | [view interactions] | High throughput | no | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| PO2F1_HUMAN | [view interactions] | High throughput | no | yes |
| NFYA_HUMAN | [view interactions] | High throughput | no | yes |
| PWP1_HUMAN | [view interactions] | High throughput | no | no |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| CENPE_HUMAN | [view interactions] | High throughput | no | no |
| CEP78_HUMAN | [view interactions] | High throughput | no | yes |
| RL29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LLPH_HUMAN | [view interactions] | High throughput | no | no |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SRFB1_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| DDX10_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBIS_HUMAN | [view interactions] | High throughput | no | no |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| NOM1_HUMAN | [view interactions] | High throughput | no | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| CRBG3_HUMAN | [view interactions] | High throughput | no | no |
| RPAC2_HUMAN | [view interactions] | High throughput | no | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO4_HUMAN | [view interactions] | High throughput | no | no |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HEXB_HUMAN | [view interactions] | High throughput | no | no |
| MCTS1_HUMAN | [view interactions] | High throughput | no | no |
| TFIP8_HUMAN | [view interactions] | High throughput | no | no |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX56_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASP_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX33_HUMAN | [view interactions] | High throughput | no | yes |
| IPO9_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| IMA6_HUMAN | [view interactions] | High throughput | no | yes |
| TAF1D_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| UBP50_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCAM3_HUMAN | [view interactions] | High throughput | no | no |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PR15A_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| RS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3B_HUMAN | [view interactions] | Computational | no | yes |
| NUP98_HUMAN | [view interactions] | Computational | no | no |
| ABCE1_HUMAN | [view interactions] | Computational | no | yes |
| IPO8_HUMAN | [view interactions] | Computational | no | no |
| IMA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IPO11_HUMAN | [view interactions] | Computational | no | yes |
| SENP1_HUMAN | [view interactions] | Computational | no | no |
| RPA2_HUMAN | [view interactions] | Computational | no | no |