DTBP1_HUMAN
Evidence for PS localization
Functions
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DTBP1_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 22.0588 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DTBP1_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 47.0588 | 4 | yes |
| GO:0071702 | organic substance transport | 44.1176 | 4 | no |
| GO:0071705 | nitrogen compound transport | 44.1176 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 42.6471 | 4 | yes |
| GO:0006996 | organelle organization | 42.6471 | 4 | yes |
| GO:0015031 | protein transport | 39.7059 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 36.7647 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 36.7647 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.3529 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 32.3529 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 29.4118 | 4 | yes |
| GO:0022607 | cellular component assembly | 29.4118 | 4 | yes |
| GO:0030030 | cell projection organization | 27.9412 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 26.4706 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 26.4706 | 4 | yes |
| GO:0010646 | regulation of cell communication | 26.4706 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.0000 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 25.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 23.5294 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 22.0588 | 5 | yes |
| GO:0051049 | regulation of transport | 22.0588 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 22.0588 | 5 | yes |
| GO:0006886 | intracellular protein transport | 22.0588 | 4 | no |
| GO:0010468 | regulation of gene expression | 22.0588 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.5882 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 20.5882 | 4 | no |
| GO:0048193 | Golgi vesicle transport | 20.5882 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 20.5882 | 5 | yes |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 19.1176 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 19.1176 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 19.1176 | 5 | yes |
| GO:0051650 | establishment of vesicle localization | 17.6471 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 17.6471 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 17.6471 | 4 | yes |
| GO:0030031 | cell projection assembly | 17.6471 | 5 | yes |
| GO:0099111 | microtubule-based transport | 16.1765 | 4 | yes |
| GO:0099518 | vesicle cytoskeletal trafficking | 16.1765 | 5 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 16.1765 | 6 | yes |
| GO:0010970 | transport along microtubule | 16.1765 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 14.7059 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 14.7059 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 14.7059 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 14.7059 | 6 | yes |
| GO:0070925 | organelle assembly | 14.7059 | 5 | yes |
| GO:0072384 | organelle transport along microtubule | 14.7059 | 4 | yes |
| GO:0072657 | protein localization to membrane | 14.7059 | 4 | yes |
| GO:0098930 | axonal transport | 14.7059 | 6 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 14.7059 | 6 | yes |
| GO:0008088 | axo-dendritic transport | 14.7059 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 14.7059 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 14.7059 | 5 | yes |
| GO:0033365 | protein localization to organelle | 13.2353 | 5 | yes |
| GO:0047496 | vesicle transport along microtubule | 13.2353 | 5 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 13.2353 | 5 | yes |
| GO:0008089 | anterograde axonal transport | 13.2353 | 7 | yes |
| GO:0010941 | regulation of cell death | 13.2353 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 13.2353 | 6 | yes |
| GO:0044782 | cilium organization | 11.7647 | 5 | yes |
| GO:0048489 | synaptic vesicle transport | 11.7647 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 11.7647 | 6 | yes |
| GO:0060271 | cilium assembly | 11.7647 | 6 | yes |
| GO:0097479 | synaptic vesicle localization | 11.7647 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 11.7647 | 4 | yes |
| GO:0031175 | neuron projection development | 10.2941 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 10.2941 | 6 | yes |
| GO:0042325 | regulation of phosphorylation | 10.2941 | 7 | yes |
| GO:0051050 | positive regulation of transport | 10.2941 | 4 | yes |
| GO:1990778 | protein localization to cell periphery | 10.2941 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 10.2941 | 7 | yes |
| GO:0010975 | regulation of neuron projection development | 10.2941 | 7 | yes |
| GO:0016050 | vesicle organization | 10.2941 | 5 | yes |
| GO:0043269 | regulation of ion transport | 8.8235 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 8.8235 | 7 | yes |
| GO:0048490 | anterograde synaptic vesicle transport | 8.8235 | 7 | yes |
| GO:0060548 | negative regulation of cell death | 8.8235 | 5 | yes |
| GO:0099514 | synaptic vesicle cytoskeletal transport | 8.8235 | 5 | yes |
| GO:0099517 | synaptic vesicle transport along microtubule | 8.8235 | 6 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 8.8235 | 6 | yes |
| GO:0031400 | negative regulation of protein modification process | 7.3529 | 7 | yes |
| GO:0032990 | cell part morphogenesis | 7.3529 | 4 | yes |
| GO:0042326 | negative regulation of phosphorylation | 7.3529 | 8 | yes |
| GO:0048858 | cell projection morphogenesis | 7.3529 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 7.3529 | 5 | yes |
| GO:0050807 | regulation of synapse organization | 7.3529 | 5 | yes |
| GO:0051046 | regulation of secretion | 7.3529 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 7.3529 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 7.3529 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 7.3529 | 4 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 7.3529 | 6 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 7.3529 | 8 | yes |
| GO:0010628 | positive regulation of gene expression | 7.3529 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 5.8824 | 7 | yes |
| GO:0042327 | positive regulation of phosphorylation | 5.8824 | 8 | yes |
| GO:0043270 | positive regulation of ion transport | 5.8824 | 5 | yes |
| GO:0043393 | regulation of protein binding | 5.8824 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 5.8824 | 5 | yes |
| GO:0045859 | regulation of protein kinase activity | 5.8824 | 6 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 5.8824 | 7 | yes |
| GO:0048812 | neuron projection morphogenesis | 5.8824 | 7 | yes |
| GO:0051338 | regulation of transferase activity | 5.8824 | 4 | yes |
| GO:1903530 | regulation of secretion by cell | 5.8824 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 5.8824 | 8 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 5.8824 | 6 | yes |
| GO:0030100 | regulation of endocytosis | 4.4118 | 5 | yes |
| GO:0032091 | negative regulation of protein binding | 4.4118 | 5 | yes |
| GO:0032438 | melanosome organization | 4.4118 | 7 | yes |
| GO:0048259 | regulation of receptor-mediated endocytosis | 4.4118 | 6 | yes |
| GO:0048753 | pigment granule organization | 4.4118 | 6 | yes |
| GO:0051047 | positive regulation of secretion | 4.4118 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 4.4118 | 4 | yes |
| GO:0051100 | negative regulation of binding | 4.4118 | 4 | yes |
| GO:0060998 | regulation of dendritic spine development | 4.4118 | 4 | yes |
| GO:0061512 | protein localization to cilium | 4.4118 | 6 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 4.4118 | 7 | yes |
| GO:1901214 | regulation of neuron death | 4.4118 | 5 | yes |
| GO:1903441 | protein localization to ciliary membrane | 4.4118 | 5 | yes |
| GO:1903532 | positive regulation of secretion by cell | 4.4118 | 5 | yes |
| GO:0002090 | regulation of receptor internalization | 4.4118 | 7 | yes |
| GO:0007420 | brain development | 4.4118 | 4 | yes |
| GO:0017157 | regulation of exocytosis | 4.4118 | 5 | yes |
| GO:0031345 | negative regulation of cell projection organization | 2.9412 | 6 | yes |
| GO:0033363 | secretory granule organization | 2.9412 | 6 | yes |
| GO:0033673 | negative regulation of kinase activity | 2.9412 | 6 | yes |
| GO:0043086 | negative regulation of catalytic activity | 2.9412 | 4 | yes |
| GO:0046928 | regulation of neurotransmitter secretion | 2.9412 | 4 | yes |
| GO:0048813 | dendrite morphogenesis | 2.9412 | 8 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 2.9412 | 5 | yes |
| GO:0050890 | cognition | 2.9412 | 4 | yes |
| GO:0051348 | negative regulation of transferase activity | 2.9412 | 5 | yes |
| GO:0051588 | regulation of neurotransmitter transport | 2.9412 | 5 | yes |
| GO:0051966 | regulation of synaptic transmission, glutamatergic | 2.9412 | 6 | yes |
| GO:0060155 | platelet dense granule organization | 2.9412 | 7 | yes |
| GO:0061000 | negative regulation of dendritic spine development | 2.9412 | 5 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 2.9412 | 5 | yes |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 2.9412 | 8 | yes |
| GO:0099175 | regulation of postsynapse organization | 2.9412 | 6 | yes |
| GO:1903305 | regulation of regulated secretory pathway | 2.9412 | 6 | yes |
| GO:2000300 | regulation of synaptic vesicle exocytosis | 2.9412 | 5 | yes |
| GO:0006469 | negative regulation of protein kinase activity | 2.9412 | 7 | yes |
| GO:0007599 | hemostasis | 2.9412 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DTBP1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 5.8824 | 3 | no |
| DOID:1289 | neurodegenerative disease | 4.4118 | 4 | no |
| DOID:12377 | spinal muscular atrophy | 2.9412 | 6 | no |
| DOID:231 | motor neuron disease | 2.9412 | 5 | no |
| DOID:0050700 | cardiomyopathy | 2.9412 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 2.9412 | 5 | no |
| DOID:0080000 | muscular disease | 2.9412 | 3 | no |
| DOID:114 | heart disease | 2.9412 | 3 | no |
| DOID:423 | myopathy | 2.9412 | 5 | no |
| DOID:66 | muscle tissue disease | 2.9412 | 4 | no |
| DOID:9884 | muscular dystrophy | 2.9412 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BL1S6_HUMAN | [view interactions] | Low throughput | no | yes |
| BL1S5_HUMAN | [view interactions] | Low throughput | no | yes |
| SNAPN_HUMAN | [view interactions] | Low throughput | no | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DTNB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DTNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CMYA5_HUMAN | [view interactions] | Low throughput | no | no |
| XRCC6_HUMAN | [view interactions] | Low throughput | no | yes |
| XRCC5_HUMAN | [view interactions] | Low throughput | no | yes |
| DOPO_HUMAN | [view interactions] | Low throughput | no | no |
| ATP7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BL1S2_HUMAN | [view interactions] | Low throughput | no | yes |
| BL1S1_HUMAN | [view interactions] | Low throughput | no | yes |
| DMD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NECD_HUMAN | [view interactions] | Low throughput | no | no |
| CCND3_HUMAN | [view interactions] | Low throughput | no | no |
| TRI32_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| THIO_HUMAN | [view interactions] | Low throughput | no | yes |
| CCND2_HUMAN | [view interactions] | Low throughput | no | yes |
| CCND1_HUMAN | [view interactions] | Low throughput | no | yes |
| TIF1A_HUMAN | [view interactions] | Low throughput | no | yes |
| RN151_HUMAN | [view interactions] | Low throughput | no | no |
| VRK2_HUMAN | [view interactions] | Low throughput | no | no |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| PWP2_HUMAN | [view interactions] | High throughput | no | no |
| TTC27_HUMAN | [view interactions] | High throughput | no | yes |
| LYG2_HUMAN | [view interactions] | High throughput | no | no |
| DUS14_HUMAN | [view interactions] | High throughput | no | yes |
| IF1AX_HUMAN | [view interactions] | High throughput | no | yes |
| LRC15_HUMAN | [view interactions] | High throughput | no | no |
| DSG4_HUMAN | [view interactions] | High throughput | no | no |
| VSIG8_HUMAN | [view interactions] | High throughput | no | no |
| SNH28_HUMAN | [view interactions] | High throughput | no | no |
| HPHL1_HUMAN | [view interactions] | High throughput | no | no |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SBP1_HUMAN | [view interactions] | High throughput | no | no |
| COPZ1_HUMAN | [view interactions] | High throughput | no | no |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNKS1_HUMAN | [view interactions] | High throughput | no | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP6_HUMAN | [view interactions] | High throughput | no | no |
| TF3B_HUMAN | [view interactions] | High throughput | no | yes |
| SFR1_HUMAN | [view interactions] | High throughput | no | no |
| CCNA2_HUMAN | [view interactions] | High throughput | no | no |
| SYBU_HUMAN | [view interactions] | High throughput | no | yes |
| BICRL_HUMAN | [view interactions] | High throughput | no | yes |
| K0408_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBNS5_HUMAN | [view interactions] | High throughput | no | yes |
| ZN490_HUMAN | [view interactions] | High throughput | no | no |
| OSBL9_HUMAN | [view interactions] | High throughput | no | yes |
| TXLNB_HUMAN | [view interactions] | High throughput | no | no |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S4_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S3_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3B2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCRL_HUMAN | [view interactions] | High throughput | no | yes |
| KANL1_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| CC153_HUMAN | [view interactions] | High throughput | no | no |
| P4HA3_HUMAN | [view interactions] | High throughput | no | no |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV7_HUMAN | [view interactions] | High throughput | no | no |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| SHFL_HUMAN | [view interactions] | High throughput | no | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| K2C75_HUMAN | [view interactions] | High throughput | no | no |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARFP2_HUMAN | [view interactions] | High throughput | no | no |
| DGC6L_HUMAN | [view interactions] | High throughput | no | no |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUF2_HUMAN | [view interactions] | High throughput | no | no |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| CC146_HUMAN | [view interactions] | High throughput | no | yes |
| NECA2_HUMAN | [view interactions] | High throughput | no | yes |
| TEX35_HUMAN | [view interactions] | High throughput | no | no |
| TRI74_HUMAN | [view interactions] | High throughput | no | no |
| BBLN_HUMAN | [view interactions] | High throughput | no | yes |
| VPS53_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M1_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA2_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASPM_HUMAN | [view interactions] | High throughput | no | no |
| PCNT_HUMAN | [view interactions] | High throughput | no | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| AP3D1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| TACC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRCA2_HUMAN | [view interactions] | High throughput | no | no |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS50_HUMAN | [view interactions] | High throughput | no | yes |
| KIF5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMC2_HUMAN | [view interactions] | High throughput | no | no |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS51_HUMAN | [view interactions] | High throughput | no | yes |
| AP3B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAV1_HUMAN | [view interactions] | High throughput | no | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CETN3_HUMAN | [view interactions] | High throughput | no | yes |
| COG5_HUMAN | [view interactions] | High throughput | no | yes |
| ALMS1_HUMAN | [view interactions] | High throughput | no | no |
| CE290_HUMAN | [view interactions] | High throughput | no | no |
| GDC_HUMAN | [view interactions] | High throughput | no | no |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| FA83H_HUMAN | [view interactions] | High throughput | no | yes |
| BCAS4_HUMAN | [view interactions] | High throughput | no | yes |
| BORC8_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP3S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| COG7_HUMAN | [view interactions] | High throughput | no | yes |
| STX8_HUMAN | [view interactions] | High throughput | no | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP8_HUMAN | [view interactions] | High throughput | no | no |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF7_HUMAN | [view interactions] | High throughput | no | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3S2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX7_HUMAN | [view interactions] | High throughput | no | yes |
| TRI69_HUMAN | [view interactions] | High throughput | no | no |
| TSKS_HUMAN | [view interactions] | High throughput | no | no |
| GGA1_HUMAN | [view interactions] | High throughput | no | yes |
| AKND1_HUMAN | [view interactions] | High throughput | no | no |
| TRAK2_HUMAN | [view interactions] | High throughput | no | yes |
| TRIMM_HUMAN | [view interactions] | High throughput | no | no |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| ANGP4_HUMAN | [view interactions] | High throughput | no | no |
| KLC3_HUMAN | [view interactions] | High throughput | no | no |
| HPS6_HUMAN | [view interactions] | Computational | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| HPS5_HUMAN | [view interactions] | Computational | no | yes |
| NRG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DAOA_HUMAN | [view interactions] | Computational | no | no |
| TXND5_HUMAN | [view interactions] | Computational | no | yes |
| HPS3_HUMAN | [view interactions] | Computational | no | yes |
| SNAA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HPS4_HUMAN | [view interactions] | Computational | no | yes |