Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PRKDC_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (PubMed, PubMed, PubMed). Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C) (PubMed). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step (PubMed, PubMed, PubMed, PubMed). Required to protect and align broken ends of DNA (PubMed, PubMed, PubMed, PubMed). May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage (PubMed, PubMed, PubMed, PubMed). Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription (PubMed, PubMed, PubMed, PubMed). As part of the DNA-PK complex, involved in the early steps of ribosome assembly by promoting the processing of precursor rRNA into mature 18S rRNA in the small-subunit processome (PubMed). Binding to U3 small nucleolar RNA, recruits PRKDC and XRCC5/Ku86 to the small-subunit processome (PubMed). Recognizes the substrate consensus sequence [ST]-Q (PubMed, PubMed, PubMed, PubMed). Phosphorylates Ser-139 of histone variant H2AX, thereby regulating DNA damage response mechanism (PubMed, PubMed). Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, FH, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2 (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA (PubMed). Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D (PubMed). Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 Ser-588 and increasing CRY1 protein stability, most likely through an indirect mechanism . Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
3062 Leu Arg Immunodeficiency26withorwithoutneurologicabnormalities(IMD26) -
3574 Ala Val Immunodeficiency26withorwithoutneurologicabnormalities(IMD26) -

Linear motifs

ELM instance Name Type Start End Partner
ELMI001906 CLV_C14_Caspase3-7 CLV 2710 2714 -
ELMI001906 CLV_C14_Caspase3-7 CLV 2710 2714 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PRKDC_HUMAN
GO:0043168 anion binding 34.7222 4 yes
GO:0000166 nucleotide binding 34.0278 4 yes
GO:0017076 purine nucleotide binding 34.0278 5 yes
GO:0032555 purine ribonucleotide binding 32.6389 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 32.6389 4 yes
GO:0030554 adenyl nucleotide binding 30.5556 6 yes
GO:0043169 cation binding 30.5556 4 no
GO:0005524 ATP binding 29.1667 5 yes
GO:0032559 adenyl ribonucleotide binding 29.1667 5 yes
GO:0046872 metal ion binding 29.1667 5 no
GO:0003723 RNA binding 26.3889 4 yes
GO:0019900 kinase binding 22.9167 4 no
GO:0019901 protein kinase binding 22.2222 5 no
GO:0016301 kinase activity 19.4444 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 19.4444 4 yes
GO:0003677 DNA binding 14.5833 4 yes
GO:0004674 protein serine/threonine kinase activity 14.5833 4 yes
GO:0106310 protein serine kinase activity 13.8889 4 yes
GO:0140297 DNA-binding transcription factor binding 13.1944 4 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9.0278 5 yes
GO:0003690 double-stranded DNA binding 8.3333 5 yes
GO:0035173 histone kinase activity 2.7778 4 yes
GO:0035979 histone H2AXS139 kinase activity 2.0833 5 yes
GO:0141003 histone H2AX kinase activity 2.0833 5 yes
GO:0004677 DNA-dependent protein kinase activity 1.3889 5 yes
GO:0030515 snoRNA binding 1.3889 5 yes
GO:0034511 U3 snoRNA binding 1.3889 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PRKDC_HUMAN
GO:0048522 positive regulation of cellular process 69.4444 4 yes
GO:0060255 regulation of macromolecule metabolic process 67.3611 4 yes
GO:0080090 regulation of primary metabolic process 66.6667 4 yes
GO:0031323 regulation of cellular metabolic process 63.8889 4 yes
GO:0048523 negative regulation of cellular process 61.1111 4 yes
GO:0009889 regulation of biosynthetic process 56.9444 4 yes
GO:0031326 regulation of cellular biosynthetic process 56.2500 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 54.8611 5 yes
GO:0010468 regulation of gene expression 53.4722 6 yes
GO:0009893 positive regulation of metabolic process 52.7778 4 yes
GO:0010646 regulation of cell communication 52.7778 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 yes
GO:0009966 regulation of signal transduction 48.6111 4 yes
GO:0051246 regulation of protein metabolic process 46.5278 5 yes
GO:0051128 regulation of cellular component organization 46.5278 4 no
GO:0009892 negative regulation of metabolic process 45.8333 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 43.7500 5 yes
GO:0031325 positive regulation of cellular metabolic process 43.7500 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 43.0556 5 yes
GO:0031324 negative regulation of cellular metabolic process 41.6667 5 yes
GO:0009891 positive regulation of biosynthetic process 38.8889 5 yes
GO:0006996 organelle organization 38.1944 4 yes
GO:0022607 cellular component assembly 38.1944 4 yes
GO:0031328 positive regulation of cellular biosynthetic process 38.1944 6 yes
GO:0048584 positive regulation of response to stimulus 36.8056 4 yes
GO:0051252 regulation of RNA metabolic process 36.1111 5 yes
GO:0023056 positive regulation of signaling 36.1111 4 no
GO:1902531 regulation of intracellular signal transduction 36.1111 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 36.1111 6 yes
GO:0010647 positive regulation of cell communication 35.4167 5 no
GO:0043067 regulation of programmed cell death 34.7222 4 yes
GO:0042981 regulation of apoptotic process 34.7222 5 yes
GO:0008104 protein localization 34.0278 4 no
GO:0043412 macromolecule modification 32.6389 4 yes
GO:0048585 negative regulation of response to stimulus 31.9444 4 yes
GO:0009894 regulation of catabolic process 31.9444 4 no
GO:0036211 protein modification process 31.9444 4 yes
GO:0051247 positive regulation of protein metabolic process 31.2500 6 yes
GO:2001141 regulation of RNA biosynthetic process 31.2500 6 yes
GO:0009967 positive regulation of signal transduction 31.2500 5 no
GO:0006355 regulation of DNA-templated transcription 31.2500 7 yes
GO:0031399 regulation of protein modification process 30.5556 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 29.8611 5 yes
GO:0010648 negative regulation of cell communication 29.8611 5 yes
GO:0023057 negative regulation of signaling 29.8611 4 yes
GO:0009968 negative regulation of signal transduction 29.1667 5 yes
GO:0033043 regulation of organelle organization 28.4722 5 no
GO:0009890 negative regulation of biosynthetic process 28.4722 5 no
GO:0031327 negative regulation of cellular biosynthetic process 27.7778 6 no
GO:0006796 phosphate-containing compound metabolic process 27.7778 4 yes
GO:0071310 cellular response to organic substance 27.0833 4 yes
GO:0051049 regulation of transport 27.0833 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 27.0833 6 no
GO:0051174 regulation of phosphorus metabolic process 26.3889 5 yes
GO:0080134 regulation of response to stress 26.3889 4 yes
GO:0060341 regulation of cellular localization 26.3889 4 no
GO:0019220 regulation of phosphate metabolic process 26.3889 6 yes
GO:0042127 regulation of cell population proliferation 25.0000 4 yes
GO:0051240 positive regulation of multicellular organismal process 24.3056 4 yes
GO:0051248 negative regulation of protein metabolic process 24.3056 6 yes
GO:0051130 positive regulation of cellular component organization 24.3056 5 no
GO:0044087 regulation of cellular component biogenesis 24.3056 4 no
GO:0043066 negative regulation of apoptotic process 23.6111 6 yes
GO:0043069 negative regulation of programmed cell death 23.6111 5 yes
GO:0043933 protein-containing complex organization 23.6111 4 yes
GO:0090304 nucleic acid metabolic process 23.6111 4 yes
GO:0032880 regulation of protein localization 23.6111 5 no
GO:0071702 organic substance transport 23.6111 4 no
GO:0010628 positive regulation of gene expression 23.6111 7 yes
GO:0051254 positive regulation of RNA metabolic process 22.9167 6 yes
GO:0010243 response to organonitrogen compound 22.9167 4 yes
GO:0045595 regulation of cell differentiation 22.2222 4 yes
GO:1902533 positive regulation of intracellular signal transduction 22.2222 6 no
GO:0042325 regulation of phosphorylation 22.2222 7 yes
GO:0045893 positive regulation of DNA-templated transcription 20.8333 8 yes
GO:0051094 positive regulation of developmental process 20.8333 4 yes
GO:1901701 cellular response to oxygen-containing compound 20.8333 4 yes
GO:1902680 positive regulation of RNA biosynthetic process 20.8333 7 yes
GO:0031401 positive regulation of protein modification process 20.8333 7 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 20.8333 5 no
GO:0001932 regulation of protein phosphorylation 20.8333 7 yes
GO:0006357 regulation of transcription by RNA polymerase II 20.8333 8 yes
GO:0016310 phosphorylation 20.8333 5 yes
GO:0051726 regulation of cell cycle 20.1389 4 yes
GO:2000026 regulation of multicellular organismal development 20.1389 4 yes
GO:0051338 regulation of transferase activity 20.1389 4 no
GO:0051129 negative regulation of cellular component organization 20.1389 5 no
GO:0071705 nitrogen compound transport 20.1389 4 no
GO:0032101 regulation of response to external stimulus 18.0556 4 yes
GO:1901699 cellular response to nitrogen compound 16.6667 4 yes
GO:0060284 regulation of cell development 15.9722 5 yes
GO:0071417 cellular response to organonitrogen compound 15.9722 4 yes
GO:0006468 protein phosphorylation 15.9722 5 yes
GO:0031400 negative regulation of protein modification process 15.9722 7 yes
GO:0045936 negative regulation of phosphate metabolic process 15.2778 7 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 15.2778 9 yes
GO:0051052 regulation of DNA metabolic process 15.2778 5 yes
GO:0065003 protein-containing complex assembly 15.2778 5 yes
GO:0006974 DNA damage response 15.2778 4 yes
GO:0010563 negative regulation of phosphorus metabolic process 15.2778 6 yes
GO:0080135 regulation of cellular response to stress 14.5833 4 yes
GO:0010564 regulation of cell cycle process 14.5833 5 yes
GO:0016070 RNA metabolic process 14.5833 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 14.5833 4 yes
GO:0045597 positive regulation of cell differentiation 13.1944 5 yes
GO:0002684 positive regulation of immune system process 13.1944 4 yes
GO:0006259 DNA metabolic process 13.1944 5 yes
GO:0010608 post-transcriptional regulation of gene expression 13.1944 7 yes
GO:0018193 peptidyl-amino acid modification 13.1944 5 yes
GO:0043068 positive regulation of programmed cell death 12.5000 5 yes
GO:0050776 regulation of immune response 12.5000 4 yes
GO:0042326 negative regulation of phosphorylation 12.5000 8 yes
GO:0043065 positive regulation of apoptotic process 11.8056 6 yes
GO:0001933 negative regulation of protein phosphorylation 11.8056 8 yes
GO:0032870 cellular response to hormone stimulus 11.8056 4 yes
GO:0051054 positive regulation of DNA metabolic process 11.1111 6 yes
GO:0006281 DNA repair 11.1111 5 yes
GO:0006417 regulation of translation 11.1111 6 yes
GO:0031347 regulation of defense response 11.1111 5 yes
GO:0043434 response to peptide hormone 10.4167 4 yes
GO:0050865 regulation of cell activation 10.4167 4 yes
GO:0051249 regulation of lymphocyte activation 9.0278 5 yes
GO:0071375 cellular response to peptide hormone stimulus 9.0278 5 yes
GO:0140546 defense response to symbiont 9.0278 4 yes
GO:0002694 regulation of leukocyte activation 9.0278 4 yes
GO:0010720 positive regulation of cell development 9.0278 6 yes
GO:0032103 positive regulation of response to external stimulus 9.0278 5 yes
GO:0045088 regulation of innate immune response 8.3333 5 yes
GO:0050778 positive regulation of immune response 8.3333 5 yes
GO:0002831 regulation of response to biotic stimulus 8.3333 4 yes
GO:0018105 peptidyl-serine phosphorylation 8.3333 6 yes
GO:0018209 peptidyl-serine modification 8.3333 6 yes
GO:0050867 positive regulation of cell activation 7.6389 5 yes
GO:0051276 chromosome organization 7.6389 5 yes
GO:1903706 regulation of hemopoiesis 7.6389 4 yes
GO:0006396 RNA processing 7.6389 6 yes
GO:0007346 regulation of mitotic cell cycle 7.6389 5 yes
GO:0045786 negative regulation of cell cycle 6.9444 5 yes
GO:0050678 regulation of epithelial cell proliferation 6.9444 5 yes
GO:0051251 positive regulation of lymphocyte activation 6.9444 6 yes
GO:1902105 regulation of leukocyte differentiation 6.9444 5 yes
GO:0002683 negative regulation of immune system process 6.9444 4 yes
GO:0002696 positive regulation of leukocyte activation 6.9444 5 yes
GO:0097193 intrinsic apoptotic signaling pathway 6.2500 4 yes
GO:1901987 regulation of cell cycle phase transition 6.2500 6 yes
GO:1903131 mononuclear cell differentiation 6.2500 5 yes
GO:0002521 leukocyte differentiation 6.2500 4 yes
GO:0006302 double-strand break repair 6.2500 6 yes
GO:0007507 heart development 6.2500 4 yes
GO:0032868 response to insulin 6.2500 5 yes
GO:0045089 positive regulation of innate immune response 5.5556 6 yes
GO:0048660 regulation of smooth muscle cell proliferation 5.5556 5 yes
GO:0000723 telomere maintenance 5.5556 6 yes
GO:0002833 positive regulation of response to biotic stimulus 5.5556 5 yes
GO:0031349 positive regulation of defense response 5.5556 5 yes
GO:0032200 telomere organization 5.5556 6 yes
GO:0045619 regulation of lymphocyte differentiation 4.8611 6 yes
GO:0045727 positive regulation of translation 4.8611 7 yes
GO:0006282 regulation of DNA repair 4.8611 5 yes
GO:0010948 negative regulation of cell cycle process 4.8611 6 yes
GO:0018107 peptidyl-threonine phosphorylation 4.8611 6 yes
GO:0018210 peptidyl-threonine modification 4.8611 6 yes
GO:0032869 cellular response to insulin stimulus 4.8611 6 yes
GO:0042113 B cell activation 4.8611 4 yes
GO:0045637 regulation of myeloid cell differentiation 4.1667 5 yes
GO:0062207 regulation of pattern recognition receptor signaling pathway 4.1667 5 yes
GO:0071826 protein-RNA complex organization 4.1667 5 yes
GO:1901990 regulation of mitotic cell cycle phase transition 4.1667 6 yes
GO:1902806 regulation of cell cycle G1/S phase transition 4.1667 7 yes
GO:2000779 regulation of double-strand break repair 4.1667 6 yes
GO:0010212 response to ionizing radiation 4.1667 4 yes
GO:0042110 T cell activation 4.1667 4 yes
GO:0042770 signal transduction in response to DNA damage 4.1667 4 yes
GO:0045621 positive regulation of lymphocyte differentiation 3.4722 7 yes
GO:0045739 positive regulation of DNA repair 3.4722 5 yes
GO:0045930 negative regulation of mitotic cell cycle 3.4722 6 yes
GO:1902107 positive regulation of leukocyte differentiation 3.4722 6 yes
GO:1903708 positive regulation of hemopoiesis 3.4722 5 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 3.4722 7 yes
GO:2000736 regulation of stem cell differentiation 3.4722 5 yes
GO:0002360 T cell lineage commitment 3.4722 4 yes
GO:0022618 protein-RNA complex assembly 3.4722 6 yes
GO:0030098 lymphocyte differentiation 3.4722 4 yes
GO:0031648 protein destabilization 3.4722 4 yes
GO:0045646 regulation of erythrocyte differentiation 2.7778 6 yes
GO:0141188 nucleic acid catabolic process 2.7778 5 yes
GO:0160049 negative regulation of cGAS/STING signaling pathway 2.7778 6 yes
GO:1901532 regulation of hematopoietic progenitor cell differentiation 2.7778 5 yes
GO:1901988 negative regulation of cell cycle phase transition 2.7778 7 yes
GO:2000781 positive regulation of double-strand break repair 2.7778 6 yes
GO:0002244 hematopoietic progenitor cell differentiation 2.7778 4 yes
GO:0006310 DNA recombination 2.7778 6 yes
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 2.7778 5 yes
GO:0010332 response to gamma radiation 2.7778 5 yes
GO:0022604 regulation of cell morphogenesis 2.7778 5 yes
GO:0030183 B cell differentiation 2.7778 5 yes
GO:0030217 T cell differentiation 2.7778 5 yes
GO:0033077 T cell differentiation in thymus 2.7778 6 yes
GO:0039531 regulation of cytoplasmic pattern recognition receptor signaling pathway 2.7778 6 yes
GO:0039532 negative regulation of cytoplasmic pattern recognition receptor signaling pathway 2.7778 5 yes
GO:0045639 positive regulation of myeloid cell differentiation 2.0833 6 yes
GO:0045648 positive regulation of erythrocyte differentiation 2.0833 7 yes
GO:1901991 negative regulation of mitotic cell cycle phase transition 2.0833 7 yes
GO:1902036 regulation of hematopoietic stem cell differentiation 2.0833 6 yes
GO:1902807 negative regulation of cell cycle G1/S phase transition 2.0833 8 yes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2.0833 8 yes
GO:2001032 regulation of double-strand break repair via nonhomologous end joining 2.0833 7 yes
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 2.0833 7 yes
GO:0000075 cell cycle checkpoint signaling 2.0833 4 yes
GO:0000077 DNA damage checkpoint signaling 2.0833 5 yes
GO:0002327 immature B cell differentiation 2.0833 6 yes
GO:0006303 double-strand break repair via nonhomologous end joining 2.0833 7 yes
GO:0007420 brain development 2.0833 4 yes
GO:0009952 anterior/posterior pattern specification 2.0833 4 yes
GO:0010770 positive regulation of cell morphogenesis 2.0833 6 yes
GO:0031570 DNA integrity checkpoint signaling 2.0833 5 yes
GO:0044773 mitotic DNA damage checkpoint signaling 1.3889 6 yes
GO:0044774 mitotic DNA integrity checkpoint signaling 1.3889 5 yes
GO:0044819 mitotic G1/S transition checkpoint signaling 1.3889 5 yes
GO:0097681 double-strand break repair via alternative nonhomologous end joining 1.3889 8 yes
GO:1905219 regulation of platelet formation 1.3889 6 yes
GO:1905221 positive regulation of platelet formation 1.3889 7 yes
GO:0000460 maturation of 5.8S rRNA 1.3889 7 yes
GO:0002320 lymphoid progenitor cell differentiation 1.3889 5 yes
GO:0002326 B cell lineage commitment 1.3889 4 yes
GO:0002328 pro-B cell differentiation 1.3889 6 yes
GO:0002681 somatic recombination of T cell receptor gene segments 1.3889 4 yes
GO:0006364 rRNA processing 1.3889 6 yes
GO:0007093 mitotic cell cycle checkpoint signaling 1.3889 4 yes
GO:0016072 rRNA metabolic process 1.3889 6 yes
GO:0016233 telomere capping 1.3889 7 yes
GO:0016444 somatic cell DNA recombination 1.3889 7 yes
GO:0016447 somatic recombination of immunoglobulin gene segments 1.3889 4 yes
GO:0031571 mitotic G1 DNA damage checkpoint signaling 1.3889 6 yes
GO:0033151 V(D)J recombination 1.3889 4 yes
GO:0033152 immunoglobulin V(D)J recombination 1.3889 5 yes
GO:0033153 T cell receptor V(D)J recombination 1.3889 5 yes
GO:0034462 small-subunit processome assembly 1.3889 7 yes
GO:0035282 segmentation 1.3889 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
H2AX_HUMAN [view interactions] Low throughput no yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
SIN1_HUMAN [view interactions] Low throughput no yes
IBP3_HUMAN [view interactions] Low throughput no no
CDK8_HUMAN [view interactions] Low throughput no no
MED13_HUMAN [view interactions] Low throughput no no
JUN_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
DNLI4_HUMAN [view interactions] Low throughput no yes
IFFO1_HUMAN [view interactions] Low throughput no yes
ZIC2_HUMAN [view interactions] Low throughput no no
GOLP3_HUMAN [view interactions] Low throughput no no
NEMO_HUMAN [view interactions] Low throughput no yes
MYC_HUMAN [view interactions] Low throughput no yes
H31_HUMAN [view interactions] Low throughput no yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
C1D_HUMAN [view interactions] Low throughput no yes
CIB1_HUMAN [view interactions] Low throughput no no
NCOA6_HUMAN [view interactions] Low throughput no yes
RFA2_HUMAN [view interactions] Low throughput no yes
WRN_HUMAN [view interactions] Low throughput no yes
ILF3_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
VIGLN_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR6_HUMAN [view interactions] Low throughput no yes
NR1H4_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
HDAC6_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
AICDA_HUMAN [view interactions] Low throughput no no
DHX9_HUMAN [view interactions] Low throughput no yes
XRCC4_HUMAN [view interactions] Low throughput no yes
THA_HUMAN [view interactions] Low throughput no yes
THB_HUMAN [view interactions] Low throughput no no
BIRC5_HUMAN [view interactions] Low throughput no no
BMI1_HUMAN [view interactions] Low throughput no yes
PP6R2_HUMAN [view interactions] Low throughput no no
PP6R3_HUMAN [view interactions] Low throughput no yes
PIDD1_HUMAN [view interactions] Low throughput no yes
USF1_HUMAN [view interactions] Low throughput no yes
MSH6_HUMAN [view interactions] Low throughput no yes
MDC1_HUMAN [view interactions] Low throughput no yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
ARHG6_HUMAN [view interactions] Low throughput no no
RFA1_HUMAN [view interactions] Low throughput no yes
ETS1_HUMAN [view interactions] Low throughput no no
ETV1_HUMAN [view interactions] Low throughput no no
PRGR_HUMAN [view interactions] Low throughput no no
SPI1_HUMAN [view interactions] Low throughput no no
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
TTI1_HUMAN [view interactions] Low throughput no yes
LRRK2_HUMAN [view interactions] Low throughput no yes
PPP6_HUMAN [view interactions] Low throughput no yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
DPOLL_HUMAN [view interactions] Low throughput no no
RUVB2_HUMAN [view interactions] Low throughput no yes
XRCC5_HUMAN [view interactions] Low throughput no yes
XRCC6_HUMAN [view interactions] Low throughput no yes
PP6R1_HUMAN [view interactions] Low throughput no no
R144A_HUMAN [view interactions] Low throughput no yes
MRE11_HUMAN [view interactions] Low throughput no yes
CHK1_HUMAN [view interactions] Low throughput no no
DCR1C_HUMAN [view interactions] Low throughput no no
ANC2_HUMAN [view interactions] Low throughput no no
FZR1_HUMAN [view interactions] Low throughput no no
CCNB1_HUMAN [view interactions] Low throughput no no
XPA_HUMAN [view interactions] Low throughput no yes
LMNA_HUMAN [view entry] [view interactions] Low throughput yes yes
LOX15_HUMAN [view interactions] Low throughput no no
XRCC1_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT2_HUMAN [view entry] [view interactions] Low throughput yes yes
AKTIP_HUMAN [view interactions] Low throughput no yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKA_HUMAN [view interactions] Low throughput no yes
LYN_HUMAN [view entry] [view interactions] Low throughput yes no
HSF1_HUMAN [view interactions] Low throughput no yes
HIF1A_HUMAN [view interactions] Low throughput no no
NHEJ1_HUMAN [view interactions] Low throughput no yes
KAT2A_HUMAN [view interactions] Low throughput no no
IKKB_HUMAN [view interactions] Low throughput no yes
SRF_HUMAN [view interactions] Low throughput no yes
NCF1_HUMAN [view interactions] Low throughput no no
NCF2_HUMAN [view interactions] Low throughput no no
NCF4_HUMAN [view interactions] Low throughput no no
MK08_HUMAN [view interactions] Low throughput no yes
PO2F1_HUMAN [view interactions] Low throughput no yes
PDX1_HUMAN [view interactions] Low throughput no no
HDAC3_HUMAN [view interactions] Low throughput no yes
H11_HUMAN [view interactions] Low throughput no no
PRKDC_HUMAN [view entry] [view interactions] Low throughput yes yes
SP1_HUMAN [view interactions] Low throughput no yes
CTDP1_HUMAN [view interactions] Low throughput no yes
ROA1_HUMAN [view entry] [view interactions] Low throughput yes yes
HNRPC_HUMAN [view interactions] Low throughput no yes
DCAF1_HUMAN [view interactions] Low throughput no yes
MBP_HUMAN [view entry] [view interactions] Low throughput yes no
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
GSK3A_HUMAN [view interactions] Low throughput no yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
GRAB_HUMAN [view interactions] Low throughput no no
CASP3_HUMAN [view entry] [view interactions] Low throughput yes yes
4EBP1_HUMAN [view entry] [view interactions] Low throughput yes yes
TOP1_HUMAN [view interactions] Low throughput no yes
CHK2_HUMAN [view interactions] Low throughput no yes
HXB7_HUMAN [view interactions] Low throughput no yes
TYY1_HUMAN [view interactions] Low throughput no yes
FUMH_HUMAN [view entry] [view interactions] Low throughput yes yes
ERG_HUMAN [view interactions] Low throughput no yes
AAKG1_HUMAN [view interactions] Low throughput no no
HDGF_HUMAN [view interactions] Low throughput no yes
FLNA_HUMAN [view entry] [view interactions] Low throughput yes no
ATR_HUMAN [view entry] [view interactions] Low throughput yes no
DEAF1_HUMAN [view interactions] Low throughput no yes
IF2B_HUMAN [view interactions] Low throughput no yes
ZBT7A_HUMAN [view interactions] Low throughput no yes
RN146_HUMAN [view interactions] Low throughput no yes
BRCA1_HUMAN [view interactions] Low throughput no yes
PELI1_HUMAN [view interactions] Low throughput no yes
AAPK2_HUMAN [view interactions] Low throughput no yes
TELO2_HUMAN [view interactions] Low throughput no yes
FACD2_HUMAN [view interactions] Low throughput no no
ESR1_HUMAN [view interactions] Low throughput no no
ILF2_HUMAN [view interactions] Low throughput no yes
EGFR_HUMAN [view interactions] Low throughput no no
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
PDS5A_HUMAN [view interactions] High throughput no yes
YBOX3_HUMAN [view interactions] High throughput no yes
PGFRB_HUMAN [view interactions] High throughput no yes
CDCA5_HUMAN [view interactions] High throughput no yes
NFYA_HUMAN [view interactions] High throughput no yes
TYRO3_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
NFYB_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
UBR5_HUMAN [view interactions] High throughput no no
CALR_HUMAN [view entry] [view interactions] High throughput yes yes
NEK4_HUMAN [view interactions] High throughput no yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
LRC31_HUMAN [view interactions] High throughput no no
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
SNW1_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
IF2G_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
MATR3_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
UBP5_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
RPAB3_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
HMGA2_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
TCP4_HUMAN [view interactions] High throughput no yes
KI20A_HUMAN [view interactions] High throughput no yes
IF5_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
DSRAD_HUMAN [view entry] [view interactions] High throughput yes yes
PRC1_HUMAN [view interactions] High throughput no yes
MAX_HUMAN [view interactions] High throughput no yes
CD81_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
NINL_HUMAN [view interactions] High throughput no yes
SMD1_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
SMD2_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
CIC_HUMAN [view interactions] High throughput no yes
SMD3_HUMAN [view interactions] High throughput no yes
RYBP_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
SMAD3_HUMAN [view interactions] High throughput no yes
LN28A_HUMAN [view interactions] High throughput no no
F16P1_HUMAN [view interactions] High throughput no no
SRSF2_HUMAN [view interactions] High throughput no yes
HAKAI_HUMAN [view interactions] High throughput no yes
CTIP_HUMAN [view interactions] High throughput no no
SRSF1_HUMAN [view interactions] High throughput no yes
KDF1_HUMAN [view interactions] High throughput no yes
NSUN2_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
SF3B2_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
ROCK1_HUMAN [view entry] [view interactions] High throughput yes yes
MKNK1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
NFYC_HUMAN [view interactions] High throughput no no
IKBE_HUMAN [view entry] [view interactions] High throughput yes yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
IL18_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
M3K3_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
SF3B4_HUMAN [view interactions] High throughput no yes
NFKB2_HUMAN [view interactions] High throughput no yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD2_HUMAN [view interactions] High throughput no yes
RELB_HUMAN [view interactions] High throughput no yes
PBIP1_HUMAN [view entry] [view interactions] High throughput yes no
BRE1A_HUMAN [view interactions] High throughput no yes
RIPK3_HUMAN [view interactions] High throughput no no
PTH2R_HUMAN [view interactions] High throughput no no
T2H2L_HUMAN [view interactions] High throughput no no
TNR1A_HUMAN [view interactions] High throughput no yes
LRC25_HUMAN [view interactions] High throughput no yes
5MP2_HUMAN [view interactions] High throughput no yes
TNR1B_HUMAN [view interactions] High throughput no no
MAS_HUMAN [view interactions] High throughput no no
SRRM1_HUMAN [view interactions] High throughput no yes
TRADD_HUMAN [view interactions] High throughput no yes
ACM4_HUMAN [view entry] [view interactions] High throughput yes yes
GCN1_HUMAN [view interactions] High throughput no yes
DRD4_HUMAN [view entry] [view interactions] High throughput yes no
RENT1_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
CD80_HUMAN [view interactions] High throughput no no
SNF8_HUMAN [view interactions] High throughput no yes
CBX3_HUMAN [view interactions] High throughput no yes
HUMMR_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
TTI2_HUMAN [view interactions] High throughput no yes
KI2L4_HUMAN [view interactions] High throughput no no
THUM3_HUMAN [view interactions] High throughput no yes
PHKG2_HUMAN [view interactions] High throughput no no
VASN_HUMAN [view interactions] High throughput no yes
NAA15_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
NKG2D_HUMAN [view interactions] High throughput no no
UN45A_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
CRLF2_HUMAN [view interactions] High throughput no no
CWC15_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
FPR1_HUMAN [view interactions] High throughput no no
PUF60_HUMAN [view interactions] High throughput no yes
JMY_HUMAN [view interactions] High throughput no yes
HIDE1_HUMAN [view interactions] High throughput no no
NUDT5_HUMAN [view interactions] High throughput no no
RAB1A_HUMAN [view entry] [view interactions] High throughput yes yes
ADA11_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
RAB9B_HUMAN [view interactions] High throughput no yes
GPR17_HUMAN [view interactions] High throughput no no
PRP19_HUMAN [view interactions] High throughput no yes
CENPA_HUMAN [view interactions] High throughput no no
MAGA8_HUMAN [view interactions] High throughput no no
NUP85_HUMAN [view interactions] High throughput no yes
MTLR_HUMAN [view interactions] High throughput no no
NU107_HUMAN [view interactions] High throughput no no
H2A1_HUMAN [view interactions] High throughput no yes
CC018_HUMAN [view interactions] High throughput no yes
NUP35_HUMAN [view interactions] High throughput no yes
H2AZ_HUMAN [view interactions] High throughput no yes
IDD_HUMAN [view interactions] High throughput no no
WWP1_HUMAN [view interactions] High throughput no yes
TIFAB_HUMAN [view interactions] High throughput no no
GP182_HUMAN [view interactions] High throughput no no
Z3H7A_HUMAN [view interactions] High throughput no no
KATIP_HUMAN [view interactions] High throughput no yes
EFNA4_HUMAN [view interactions] High throughput no no
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
CCNC_HUMAN [view interactions] High throughput no yes
P2Y10_HUMAN [view interactions] High throughput no no
RN183_HUMAN [view interactions] High throughput no no
AN32E_HUMAN [view entry] [view interactions] High throughput yes yes
I13R2_HUMAN [view interactions] High throughput no no
NAA40_HUMAN [view interactions] High throughput no no
TTC3_HUMAN [view interactions] High throughput no yes
CSTN1_HUMAN [view entry] [view interactions] High throughput yes yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
ACM3_HUMAN [view entry] [view interactions] High throughput yes yes
PHLP1_HUMAN [view interactions] High throughput no yes
DYRK2_HUMAN [view interactions] High throughput no yes
S22AF_HUMAN [view interactions] High throughput no yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
UFO_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR3_HUMAN [view interactions] High throughput no yes
GPC5D_HUMAN [view interactions] High throughput no yes
SAR1B_HUMAN [view interactions] High throughput no yes
VGFR1_HUMAN [view interactions] High throughput no no
NK3R_HUMAN [view interactions] High throughput no no
ARL10_HUMAN [view interactions] High throughput no yes
FLT3_HUMAN [view interactions] High throughput no no
NPY2R_HUMAN [view interactions] High throughput no no
KBTB4_HUMAN [view interactions] High throughput no yes
VGFR2_HUMAN [view interactions] High throughput no no
F234A_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
LMTK1_HUMAN [view interactions] High throughput no yes
S15A1_HUMAN [view interactions] High throughput no no
LMTK2_HUMAN [view entry] [view interactions] High throughput yes yes
OPALI_HUMAN [view interactions] High throughput no yes
MERTK_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
RON_HUMAN [view interactions] High throughput no yes
DTX3_HUMAN [view interactions] High throughput no yes
ROS1_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
TIE2_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
TMPS2_HUMAN [view interactions] High throughput no no
TOP3B_HUMAN [view interactions] High throughput no no
CATL1_HUMAN [view interactions] High throughput no yes
CATB_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
CATS_HUMAN [view interactions] High throughput no no
DPP4_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
RECQ5_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
MLH1_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
PMS2_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
CLC4E_HUMAN [view interactions] High throughput no no
UHRF2_HUMAN [view interactions] High throughput no no
MGMT_HUMAN [view interactions] High throughput no no
CUL1_HUMAN [view interactions] High throughput no yes
DGCR8_HUMAN [view entry] [view interactions] High throughput yes yes
ZEB1_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
H12_HUMAN [view interactions] High throughput no yes
RHOF_HUMAN [view interactions] High throughput no no
ANR28_HUMAN [view interactions] High throughput no no
KAT8_HUMAN [view interactions] High throughput no no
FKBP5_HUMAN [view interactions] High throughput no yes
MS3L1_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
H2B2E_HUMAN [view interactions] High throughput no yes
HMGA1_HUMAN [view interactions] High throughput no yes
MAP4_HUMAN [view entry] [view interactions] High throughput yes no
NUCKS_HUMAN [view interactions] High throughput no yes
CAF1A_HUMAN [view interactions] High throughput no yes
SP16H_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
TEBP_HUMAN [view interactions] High throughput no yes
SC61B_HUMAN [view interactions] High throughput no yes
SSRP1_HUMAN [view interactions] High throughput no yes
H33_HUMAN [view interactions] High throughput no yes
ANM1_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view entry] [view interactions] High throughput yes no
FOXC1_HUMAN [view interactions] High throughput no no
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
SHCAF_HUMAN [view interactions] High throughput no yes
THEM6_HUMAN [view interactions] High throughput no no
MYCN_HUMAN [view interactions] High throughput no no
TP8L1_HUMAN [view interactions] High throughput no no
MTR1B_HUMAN [view interactions] High throughput no yes
RAD21_HUMAN [view interactions] High throughput no yes
EPAS1_HUMAN [view interactions] High throughput no no
SAP25_HUMAN [view interactions] High throughput no no
SMRCD_HUMAN [view interactions] High throughput no yes
CREM_HUMAN [view interactions] High throughput no no
NBN_HUMAN [view interactions] High throughput no yes
UBP22_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
AIMP2_HUMAN [view interactions] High throughput no yes
TOP2A_HUMAN [view interactions] High throughput no no
CYREN_HUMAN [view interactions] High throughput no yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
MLP3B_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
CEBPB_HUMAN [view interactions] High throughput no no
BAP1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
PINK1_HUMAN [view interactions] High throughput no yes
DOT1L_HUMAN [view interactions] High throughput no yes
AAKB2_HUMAN [view interactions] High throughput no yes
LOXL2_HUMAN [view interactions] High throughput no yes
NIPS2_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
SBDS_HUMAN [view interactions] High throughput no yes
CLN3_HUMAN [view interactions] High throughput no no
R113A_HUMAN [view interactions] High throughput no yes
KKCC2_HUMAN [view entry] [view interactions] High throughput yes yes
GRK5_HUMAN [view interactions] High throughput no yes
GATA4_HUMAN [view interactions] High throughput no no
DDA1_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
ATGA1_HUMAN [view interactions] High throughput no yes
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
GBRA1_HUMAN [view entry] [view interactions] High throughput yes yes
BECN1_HUMAN [view interactions] High throughput no yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
ATG4C_HUMAN [view interactions] High throughput no yes
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
RUFY1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
ELP1_HUMAN [view interactions] High throughput no yes
TRI33_HUMAN [view interactions] High throughput no yes
NPHP4_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
IQCB1_HUMAN [view interactions] High throughput no no
PNKP_HUMAN [view interactions] High throughput no yes
MBD6_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
ASXL1_HUMAN [view interactions] High throughput no no
TF2L1_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
ASXL2_HUMAN [view interactions] High throughput no no
NOS2_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
HDA11_HUMAN [view interactions] High throughput no no
ITA4_HUMAN [view interactions] High throughput no no
SRS10_HUMAN [view interactions] High throughput no yes
PAN2_HUMAN [view interactions] High throughput no no
MOB3C_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
STF1_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
RICTR_HUMAN [view interactions] High throughput no yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
SMC5_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
RFA3_HUMAN [view interactions] High throughput no yes
GRM2_HUMAN [view entry] [view interactions] High throughput yes yes
RUVB1_HUMAN [view interactions] High throughput no yes
ASB5_HUMAN [view interactions] High throughput no no
LGR4_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
UBP36_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
B3GN2_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
TF65_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP1_HUMAN [view interactions] High throughput no yes
POTE1_HUMAN [view interactions] High throughput no no
TERF1_HUMAN [view interactions] High throughput no no
CUL7_HUMAN [view interactions] High throughput no yes
RIR2_HUMAN [view interactions] High throughput no no
TINF2_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
DNJC7_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
DCR1B_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
CDK4_HUMAN [view interactions] High throughput no no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
SKI_HUMAN [view interactions] High throughput no yes
TSPO_HUMAN [view interactions] High throughput no yes
CRY1_HUMAN [view interactions] High throughput no yes
MPIP1_HUMAN [view interactions] High throughput no no
NOTC1_HUMAN [view entry] [view interactions] High throughput yes yes
CRY2_HUMAN [view interactions] High throughput no yes
LTC4S_HUMAN [view interactions] High throughput no no
LPAR4_HUMAN [view interactions] High throughput no no
EDA_HUMAN [view interactions] High throughput no no
EPHA1_HUMAN [view interactions] High throughput no yes
DCK_HUMAN [view interactions] High throughput no no
CHD1L_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
MCM2_HUMAN [view interactions] High throughput no no
KS6A2_HUMAN [view interactions] High throughput no yes
MEX3C_HUMAN [view interactions] High throughput no yes
BCAT2_HUMAN [view interactions] High throughput no no
MTG8R_HUMAN [view interactions] High throughput no yes
PO5F1_HUMAN [view interactions] High throughput no yes
MPIP2_HUMAN [view interactions] High throughput no no
RRP1B_HUMAN [view interactions] High throughput no yes
SSR4_HUMAN [view interactions] High throughput no no
MTA70_HUMAN [view interactions] High throughput no no
AHSA1_HUMAN [view entry] [view interactions] High throughput yes yes
DCXR_HUMAN [view interactions] High throughput no no
MET14_HUMAN [view interactions] High throughput no yes
NFAC2_HUMAN [view interactions] High throughput no yes
PIM1_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
PA24C_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
ATOH1_HUMAN [view interactions] High throughput no no
JAK3_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
NKX21_HUMAN [view interactions] High throughput no no
SOCS1_HUMAN [view interactions] High throughput no yes
F264_HUMAN [view interactions] High throughput no no
PTN12_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
CHD1_HUMAN [view interactions] High throughput no yes
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
ZN746_HUMAN [view interactions] High throughput no no
ELK1_HUMAN [view interactions] High throughput no yes
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
TES_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
MTF1_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP3_HUMAN [view interactions] High throughput no yes
LNX1_HUMAN [view entry] [view interactions] High throughput yes yes
ATRIP_HUMAN [view interactions] High throughput no yes
NCBP1_HUMAN [view interactions] High throughput no yes
ITB1_HUMAN [view entry] [view interactions] High throughput yes no
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
ZN598_HUMAN [view interactions] High throughput no no
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
BMR1A_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
PAXX_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
DPOD1_HUMAN [view interactions] High throughput no yes
TXTP_HUMAN [view entry] [view interactions] High throughput yes no
SIM26_HUMAN [view interactions] High throughput no no
KC1A_HUMAN [view interactions] High throughput no yes
CLC4G_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
B2CL1_HUMAN [view interactions] High throughput no yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
COPE_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
TIAM2_HUMAN [view interactions] High throughput no yes
TGFB1_HUMAN [view interactions] High throughput no no
PWP2B_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
RMD5A_HUMAN [view interactions] High throughput no yes
F161A_HUMAN [view interactions] High throughput no no
LAP2A_HUMAN [view interactions] High throughput no yes
SYNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
TPTE_HUMAN [view interactions] High throughput no no
CBPN_HUMAN [view interactions] High throughput no no
PRP8_HUMAN [view interactions] High throughput no yes
ZN840_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
AAR2_HUMAN [view interactions] High throughput no no
LAMC3_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
SYNE2_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
TBC28_HUMAN [view interactions] High throughput no no
CHD3_HUMAN [view interactions] High throughput no yes
RNF8_HUMAN [view interactions] High throughput no yes
CHD4_HUMAN [view interactions] High throughput no yes
GTPB4_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
SPDLY_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
RIOK1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
APLF_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
CLK1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
AP1B1_HUMAN [view entry] [view interactions] High throughput yes yes
E2F3_HUMAN [view interactions] High throughput no no
DCPS_HUMAN [view interactions] High throughput no yes
E4F1_HUMAN [view interactions] High throughput no yes
RARA_HUMAN [view interactions] High throughput no no
WDR76_HUMAN [view interactions] High throughput no no
RAD17_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
H4_HUMAN [view interactions] High throughput no yes
RASF1_HUMAN [view interactions] High throughput no yes
PPE1_HUMAN [view interactions] High throughput no no
H2B1B_HUMAN [view interactions] High throughput no yes
NEIL3_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
H2A1B_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
CK5P2_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
B2L14_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
M4A4A_HUMAN [view interactions] High throughput no no
UBP18_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
TF7L2_HUMAN [view interactions] High throughput no yes
SF3B6_HUMAN [view interactions] High throughput no yes
TN13B_HUMAN [view interactions] High throughput no no
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
CWC27_HUMAN [view interactions] High throughput no yes
UN93B_HUMAN [view interactions] High throughput no yes
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
THOC6_HUMAN [view interactions] High throughput no yes
P2RY6_HUMAN [view interactions] High throughput no no
TCTP_HUMAN [view entry] [view interactions] High throughput yes yes
YBOX1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
TM41B_HUMAN [view interactions] High throughput no yes
TRA2B_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
AUP1_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
RBM25_HUMAN [view interactions] High throughput no yes
FAF2_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
PRP16_HUMAN [view interactions] High throughput no yes
FXRD2_HUMAN [view interactions] High throughput no yes
UCHL3_HUMAN [view interactions] High throughput no yes
SRP14_HUMAN [view interactions] High throughput no no
UBAC2_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
TRI29_HUMAN [view interactions] High throughput no no
SMCA5_HUMAN [view interactions] High throughput no yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC2_HUMAN [view interactions] High throughput no yes
SRP54_HUMAN [view interactions] High throughput no yes
KAPCG_HUMAN [view interactions] High throughput no no
CTCF_HUMAN [view interactions] High throughput no yes
SERA_HUMAN [view entry] [view interactions] High throughput yes yes
MK04_HUMAN [view interactions] High throughput no no
ATX3_HUMAN [view interactions] High throughput no yes
RBP2_HUMAN [view interactions] High throughput no yes
GRK6_HUMAN [view interactions] High throughput no yes
VRK1_HUMAN [view interactions] High throughput no yes
PTER_HUMAN [view interactions] High throughput no yes
IRAK1_HUMAN [view interactions] High throughput no yes
S15A3_HUMAN [view interactions] High throughput no yes
THYN1_HUMAN [view interactions] High throughput no yes
PLK1_HUMAN [view interactions] High throughput no yes
TPR_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
PYRG2_HUMAN [view interactions] High throughput no yes
KC1G2_HUMAN [view interactions] High throughput no yes
DUS2_HUMAN [view interactions] High throughput no no
GTF2I_HUMAN [view interactions] High throughput no yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRU_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
MYLK_HUMAN [view entry] [view interactions] High throughput yes no
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
RTRAF_HUMAN [view interactions] High throughput no yes
STYK1_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
ADCK2_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
EHD1_HUMAN [view entry] [view interactions] High throughput yes no
ST32C_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
COQ8A_HUMAN [view interactions] High throughput no no
NFX1_HUMAN [view interactions] High throughput no yes
LRRF1_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
TRMB_HUMAN [view interactions] High throughput no yes
PSKH2_HUMAN [view interactions] High throughput no no
BRD7_HUMAN [view interactions] High throughput no yes
NUCB1_HUMAN [view interactions] High throughput no yes
PMYT1_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
RFC2_HUMAN [view interactions] High throughput no yes
LATS2_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
NRBP2_HUMAN [view interactions] High throughput no yes
SET1A_HUMAN [view interactions] High throughput no yes
THADA_HUMAN [view interactions] High throughput no yes
RPKL1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
UBA6_HUMAN [view interactions] High throughput no no
SG196_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
DFFA_HUMAN [view interactions] High throughput no yes
PLRG1_HUMAN [view interactions] High throughput no yes
HELLS_HUMAN [view interactions] High throughput no yes
DIAP1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
EMC1_HUMAN [view interactions] High throughput no yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
APEX1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
SF3B1_HUMAN [view interactions] High throughput no yes
EMC5_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
DDR2_HUMAN [view interactions] High throughput no no
MN1_HUMAN [view interactions] High throughput no yes
ACL6A_HUMAN [view interactions] High throughput no yes
SNIP1_HUMAN [view interactions] High throughput no no
IF2A_HUMAN [view entry] [view interactions] High throughput yes yes
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
ANR55_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR2_HUMAN [view interactions] High throughput no yes
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
VGFR3_HUMAN [view interactions] High throughput no yes
SMC1A_HUMAN [view interactions] High throughput no yes
RU2A_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
STAG2_HUMAN [view interactions] High throughput no yes
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes