Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PRKDC_HUMAN

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (PubMed, PubMed, PubMed). Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C) (PubMed). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step (PubMed, PubMed, PubMed, PubMed). Required to protect and align broken ends of DNA (PubMed, PubMed, PubMed, PubMed). May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage (PubMed, PubMed, PubMed, PubMed). Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription (PubMed, PubMed, PubMed, PubMed). As part of the DNA-PK complex, involved in the early steps of ribosome assembly by promoting the processing of precursor rRNA into mature 18S rRNA in the small-subunit processome (PubMed). Binding to U3 small nucleolar RNA, recruits PRKDC and XRCC5/Ku86 to the small-subunit processome (PubMed). Recognizes the substrate consensus sequence [ST]-Q (PubMed, PubMed, PubMed, PubMed). Phosphorylates Ser-139 of histone variant H2AX, thereby regulating DNA damage response mechanism (PubMed, PubMed). Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, FH, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2 (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA (PubMed). Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D (PubMed). Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 Ser-588 and increasing CRY1 protein stability, most likely through an indirect mechanism . Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed). [View more on UniProt]

Interacting region for partners were not defined.

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Position Amino acid Mutation Disease Overlap with binding region
3062 Leu Arg Immunodeficiency26withorwithoutneurologicabnormalities(IMD26) -
3574 Ala Val Immunodeficiency26withorwithoutneurologicabnormalities(IMD26) -
ELM instance Name Type Start End Partner
ELMI001906 CLV_C14_Caspase3-7 CLV 2710 2714 -

Molecular function

Term Name % Distance from the top of the tree Annotated in PRKDC_HUMAN
GO:0017076 purine nucleotide binding 34.2342 4 yes
GO:0032555 purine ribonucleotide binding 32.4324 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 32.4324 4 yes
GO:0030554 adenyl nucleotide binding 30.6306 5 yes
GO:0005524 ATP binding 28.8288 5 yes
GO:0032559 adenyl ribonucleotide binding 28.8288 5 yes
GO:0019900 kinase binding 26.1261 4 no
GO:0019901 protein kinase binding 25.2252 5 no
GO:0046872 metal ion binding 24.3243 4 no
GO:0003723 RNA binding 23.4234 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 20.7207 4 yes
GO:0016301 kinase activity 20.7207 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 20.7207 4 yes
GO:0004674 protein serine/threonine kinase activity 15.3153 4 yes
GO:0106310 protein serine kinase activity 15.3153 4 yes
GO:0140297 DNA-binding transcription factor binding 14.4144 4 yes
GO:0003677 DNA binding 11.7117 4 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9.9099 5 yes
GO:0003690 double-stranded DNA binding 7.2072 5 yes
GO:0004677 DNA-dependent protein kinase activity 1.8018 5 yes
GO:0030515 snoRNA binding 1.8018 5 yes
GO:0034511 U3 snoRNA binding 1.8018 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PRKDC_HUMAN
GO:0060255 regulation of macromolecule metabolic process 68.4685 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 67.5676 4 yes
GO:0080090 regulation of primary metabolic process 67.5676 4 yes
GO:0031323 regulation of cellular metabolic process 66.6667 4 yes
GO:0048522 positive regulation of cellular process 66.6667 4 yes
GO:0048523 negative regulation of cellular process 63.9640 4 yes
GO:0009893 positive regulation of metabolic process 54.9550 4 yes
GO:0010646 regulation of cell communication 53.1532 4 no
GO:0010468 regulation of gene expression 52.2523 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 52.2523 5 yes
GO:0009892 negative regulation of metabolic process 51.3514 4 yes
GO:0051246 regulation of protein metabolic process 51.3514 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 50.4505 5 yes
GO:0009966 regulation of signal transduction 50.4505 4 no
GO:0031325 positive regulation of cellular metabolic process 49.5495 5 yes
GO:0051128 regulation of cellular component organization 49.5495 4 no
GO:0010605 negative regulation of macromolecule metabolic process 48.6486 5 yes
GO:0031324 negative regulation of cellular metabolic process 47.7477 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 46.8468 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 45.0450 5 yes
GO:0009889 regulation of biosynthetic process 44.1441 4 yes
GO:0031326 regulation of cellular biosynthetic process 44.1441 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 42.3423 5 yes
GO:0031399 regulation of protein modification process 41.4414 6 yes
GO:0043412 macromolecule modification 39.6396 4 yes
GO:0036211 protein modification process 38.7387 4 yes
GO:0006996 organelle organization 37.8378 4 yes
GO:0010941 regulation of cell death 37.8378 4 yes
GO:0051247 positive regulation of protein metabolic process 37.8378 6 yes
GO:0048584 positive regulation of response to stimulus 36.9369 4 yes
GO:0051252 regulation of RNA metabolic process 36.9369 5 yes
GO:1902531 regulation of intracellular signal transduction 36.0360 5 no
GO:0019220 regulation of phosphate metabolic process 35.1351 6 yes
GO:0051174 regulation of phosphorus metabolic process 35.1351 5 yes
GO:0023056 positive regulation of signaling 35.1351 4 no
GO:0006355 regulation of DNA-templated transcription 34.2342 6 yes
GO:0042981 regulation of apoptotic process 34.2342 6 yes
GO:0043067 regulation of programmed cell death 34.2342 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 34.2342 7 yes
GO:2001141 regulation of RNA biosynthetic process 34.2342 6 yes
GO:0010647 positive regulation of cell communication 34.2342 5 no
GO:0080134 regulation of response to stress 32.4324 4 yes
GO:0022607 cellular component assembly 31.5315 4 yes
GO:0042325 regulation of phosphorylation 31.5315 7 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 31.5315 6 yes
GO:0048585 negative regulation of response to stimulus 31.5315 4 no
GO:0033043 regulation of organelle organization 30.6306 5 no
GO:0051248 negative regulation of protein metabolic process 30.6306 6 yes
GO:0009967 positive regulation of signal transduction 30.6306 5 no
GO:0006796 phosphate-containing compound metabolic process 29.7297 4 yes
GO:0009891 positive regulation of biosynthetic process 29.7297 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 29.7297 6 yes
GO:0010648 negative regulation of cell communication 29.7297 5 no
GO:0023057 negative regulation of signaling 29.7297 4 no
GO:0008104 protein localization 29.7297 4 no
GO:0051130 positive regulation of cellular component organization 28.8288 5 no
GO:0071310 cellular response to organic substance 28.8288 4 yes
GO:0009968 negative regulation of signal transduction 28.8288 5 no
GO:0051338 regulation of transferase activity 28.8288 4 no
GO:0001932 regulation of protein phosphorylation 27.9279 7 yes
GO:0060548 negative regulation of cell death 27.9279 5 yes
GO:0031401 positive regulation of protein modification process 27.9279 7 no
GO:0043085 positive regulation of catalytic activity 27.9279 4 no
GO:0009894 regulation of catabolic process 27.9279 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.0270 6 yes
GO:0051049 regulation of transport 26.1261 4 no
GO:0080135 regulation of cellular response to stress 26.1261 4 yes
GO:0043549 regulation of kinase activity 26.1261 5 no
GO:0071702 organic substance transport 26.1261 4 no
GO:0010628 positive regulation of gene expression 25.2252 6 yes
GO:0043066 negative regulation of apoptotic process 25.2252 7 yes
GO:0043069 negative regulation of programmed cell death 25.2252 6 yes
GO:0060341 regulation of cellular localization 24.3243 4 no
GO:0051240 positive regulation of multicellular organismal process 24.3243 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 24.3243 6 no
GO:0045937 positive regulation of phosphate metabolic process 24.3243 7 no
GO:0044087 regulation of cellular component biogenesis 23.4234 4 no
GO:0010243 response to organonitrogen compound 23.4234 4 yes
GO:0042127 regulation of cell population proliferation 23.4234 4 yes
GO:0051254 positive regulation of RNA metabolic process 23.4234 6 yes
GO:0051726 regulation of cell cycle 23.4234 4 yes
GO:1901701 cellular response to oxygen-containing compound 23.4234 4 yes
GO:0042327 positive regulation of phosphorylation 23.4234 8 no
GO:0071705 nitrogen compound transport 23.4234 4 no
GO:0016192 vesicle-mediated transport 22.5225 4 no
GO:0006357 regulation of transcription by RNA polymerase II 22.5225 7 yes
GO:0045595 regulation of cell differentiation 22.5225 4 yes
GO:0051094 positive regulation of developmental process 22.5225 4 yes
GO:0032880 regulation of protein localization 22.5225 5 no
GO:1902533 positive regulation of intracellular signal transduction 21.6216 6 no
GO:0031329 regulation of cellular catabolic process 21.6216 5 no
GO:0051129 negative regulation of cellular component organization 21.6216 5 no
GO:0016310 phosphorylation 21.6216 5 yes
GO:0045893 positive regulation of DNA-templated transcription 21.6216 7 yes
GO:1902680 positive regulation of RNA biosynthetic process 21.6216 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 21.6216 8 yes
GO:0045859 regulation of protein kinase activity 21.6216 6 no
GO:0009890 negative regulation of biosynthetic process 21.6216 5 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 21.6216 6 no
GO:0006468 protein phosphorylation 20.7207 5 yes
GO:0031400 negative regulation of protein modification process 20.7207 7 yes
GO:0051347 positive regulation of transferase activity 20.7207 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 20.7207 6 no
GO:0031327 negative regulation of cellular biosynthetic process 20.7207 6 no
GO:0015031 protein transport 20.7207 4 no
GO:0018193 peptidyl-amino acid modification 19.8198 5 yes
GO:0090304 nucleic acid metabolic process 18.9189 4 yes
GO:2000026 regulation of multicellular organismal development 18.0180 4 yes
GO:0010563 negative regulation of phosphorus metabolic process 17.1171 6 yes
GO:0010564 regulation of cell cycle process 17.1171 5 yes
GO:0043933 protein-containing complex organization 17.1171 4 yes
GO:0045936 negative regulation of phosphate metabolic process 17.1171 7 yes
GO:0051052 regulation of DNA metabolic process 17.1171 5 yes
GO:1901699 cellular response to nitrogen compound 16.2162 4 yes
GO:0010942 positive regulation of cell death 15.3153 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 15.3153 4 yes
GO:0032101 regulation of response to external stimulus 15.3153 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 15.3153 8 yes
GO:0071417 cellular response to organonitrogen compound 15.3153 4 yes
GO:0001933 negative regulation of protein phosphorylation 14.4144 8 yes
GO:0042326 negative regulation of phosphorylation 14.4144 8 yes
GO:0045597 positive regulation of cell differentiation 14.4144 5 yes
GO:0050776 regulation of immune response 14.4144 4 yes
GO:0051054 positive regulation of DNA metabolic process 14.4144 6 yes
GO:0002684 positive regulation of immune system process 13.5135 4 yes
GO:0006259 DNA metabolic process 13.5135 4 yes
GO:0006974 cellular response to DNA damage stimulus 13.5135 4 yes
GO:0018209 peptidyl-serine modification 13.5135 6 yes
GO:0060284 regulation of cell development 13.5135 5 yes
GO:0065003 protein-containing complex assembly 13.5135 5 yes
GO:0018105 peptidyl-serine phosphorylation 12.6126 6 yes
GO:0043065 positive regulation of apoptotic process 12.6126 7 yes
GO:0043068 positive regulation of programmed cell death 12.6126 6 yes
GO:1901652 response to peptide 12.6126 4 yes
GO:0006281 DNA repair 10.8108 5 yes
GO:0034248 regulation of cellular amide metabolic process 10.8108 5 yes
GO:0050865 regulation of cell activation 10.8108 4 yes
GO:1901653 cellular response to peptide 10.8108 5 yes
GO:2000112 regulation of cellular macromolecule biosynthetic process 10.8108 6 yes
GO:0002694 regulation of leukocyte activation 9.9099 4 yes
GO:0007346 regulation of mitotic cell cycle 9.9099 5 yes
GO:0010608 post-transcriptional regulation of gene expression 9.9099 6 yes
GO:0018107 peptidyl-threonine phosphorylation 9.9099 6 yes
GO:0018210 peptidyl-threonine modification 9.9099 6 yes
GO:0031347 regulation of defense response 9.9099 5 yes
GO:0032870 cellular response to hormone stimulus 9.9099 4 yes
GO:0043434 response to peptide hormone 9.9099 4 yes
GO:0050778 positive regulation of immune response 9.9099 5 yes
GO:0051249 regulation of lymphocyte activation 9.9099 5 yes
GO:0006417 regulation of translation 9.0090 6 yes
GO:0010720 positive regulation of cell development 9.0090 6 yes
GO:0016070 RNA metabolic process 9.0090 5 yes
GO:0032103 positive regulation of response to external stimulus 9.0090 5 yes
GO:0051276 chromosome organization 9.0090 5 yes
GO:2001020 regulation of response to DNA damage stimulus 9.0090 5 yes
GO:0050678 regulation of epithelial cell proliferation 8.1081 5 yes
GO:0071375 cellular response to peptide hormone stimulus 8.1081 5 yes
GO:1902105 regulation of leukocyte differentiation 8.1081 5 yes
GO:1903706 regulation of hemopoiesis 8.1081 4 yes
GO:0002521 leukocyte differentiation 7.2072 4 yes
GO:0002696 positive regulation of leukocyte activation 7.2072 5 yes
GO:0006396 RNA processing 7.2072 6 yes
GO:0022604 regulation of cell morphogenesis 7.2072 5 yes
GO:0032868 response to insulin 7.2072 5 yes
GO:0034250 positive regulation of cellular amide metabolic process 7.2072 6 yes
GO:0045786 negative regulation of cell cycle 7.2072 5 yes
GO:0048660 regulation of smooth muscle cell proliferation 7.2072 5 yes
GO:0050867 positive regulation of cell activation 7.2072 5 yes
GO:0051251 positive regulation of lymphocyte activation 7.2072 6 yes
GO:0097193 intrinsic apoptotic signaling pathway 7.2072 4 yes
GO:1901987 regulation of cell cycle phase transition 7.2072 6 yes
GO:0002831 regulation of response to biotic stimulus 6.3063 4 yes
GO:0006302 double-strand break repair 6.3063 6 yes
GO:0007507 heart development 6.3063 4 yes
GO:0045088 regulation of innate immune response 6.3063 5 yes
GO:2001022 positive regulation of response to DNA damage stimulus 6.3063 5 yes
GO:0000723 telomere maintenance 5.4054 5 yes
GO:0002833 positive regulation of response to biotic stimulus 5.4054 5 yes
GO:0006282 regulation of DNA repair 5.4054 6 yes
GO:0007420 brain development 5.4054 4 yes
GO:0010212 response to ionizing radiation 5.4054 4 yes
GO:0010769 regulation of cell morphogenesis involved in differentiation 5.4054 6 yes
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 5.4054 7 yes
GO:0010948 negative regulation of cell cycle process 5.4054 6 yes
GO:0031349 positive regulation of defense response 5.4054 5 yes
GO:0032200 telomere organization 5.4054 6 yes
GO:0032869 cellular response to insulin stimulus 5.4054 6 yes
GO:0042770 signal transduction in response to DNA damage 5.4054 4 yes
GO:0045089 positive regulation of innate immune response 5.4054 6 yes
GO:0045619 regulation of lymphocyte differentiation 5.4054 6 yes
GO:0045727 positive regulation of translation 5.4054 7 yes
GO:1901990 regulation of mitotic cell cycle phase transition 5.4054 6 yes
GO:1902806 regulation of cell cycle G1/S phase transition 5.4054 7 yes
GO:1903131 mononuclear cell differentiation 5.4054 5 yes
GO:0030098 lymphocyte differentiation 4.5045 4 yes
GO:0045637 regulation of myeloid cell differentiation 4.5045 5 yes
GO:0045739 positive regulation of DNA repair 4.5045 6 yes
GO:0045930 negative regulation of mitotic cell cycle 4.5045 6 yes
GO:0071826 ribonucleoprotein complex subunit organization 4.5045 5 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 4.5045 7 yes
GO:2000779 regulation of double-strand break repair 4.5045 7 yes
GO:0002360 T cell lineage commitment 3.6036 4 yes
GO:0006303 double-strand break repair via nonhomologous end joining 3.6036 7 yes
GO:0006310 DNA recombination 3.6036 5 yes
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 3.6036 5 yes
GO:0010332 response to gamma radiation 3.6036 5 yes
GO:0022618 ribonucleoprotein complex assembly 3.6036 6 yes
GO:0030217 T cell differentiation 3.6036 5 yes
GO:0031648 protein destabilization 3.6036 4 yes
GO:0034660 ncRNA metabolic process 3.6036 6 yes
GO:0042110 T cell activation 3.6036 4 yes
GO:0045621 positive regulation of lymphocyte differentiation 3.6036 7 yes
GO:1901988 negative regulation of cell cycle phase transition 3.6036 7 yes
GO:1902107 positive regulation of leukocyte differentiation 3.6036 6 yes
GO:1903708 positive regulation of hemopoiesis 3.6036 5 yes
GO:2000736 regulation of stem cell differentiation 3.6036 5 yes
GO:2000781 positive regulation of double-strand break repair 3.6036 7 yes
GO:0000075 cell cycle checkpoint signaling 2.7027 4 yes
GO:0000077 DNA damage checkpoint signaling 2.7027 5 yes
GO:0031570 DNA integrity checkpoint signaling 2.7027 5 yes
GO:0033077 T cell differentiation in thymus 2.7027 6 yes
GO:0034470 ncRNA processing 2.7027 7 yes
GO:0045646 regulation of erythrocyte differentiation 2.7027 6 yes
GO:1901532 regulation of hematopoietic progenitor cell differentiation 2.7027 5 yes
GO:1901991 negative regulation of mitotic cell cycle phase transition 2.7027 7 yes
GO:1902036 regulation of hematopoietic stem cell differentiation 2.7027 6 yes
GO:1902807 negative regulation of cell cycle G1/S phase transition 2.7027 8 yes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2.7027 8 yes
GO:2001032 regulation of double-strand break repair via nonhomologous end joining 2.7027 8 yes
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 2.7027 8 yes
GO:0000460 maturation of 5.8S rRNA 1.8018 9 yes
GO:0002244 hematopoietic progenitor cell differentiation 1.8018 4 yes
GO:0002320 lymphoid progenitor cell differentiation 1.8018 5 yes
GO:0002326 B cell lineage commitment 1.8018 4 yes
GO:0002328 pro-B cell differentiation 1.8018 6 yes
GO:0002681 somatic recombination of T cell receptor gene segments 1.8018 4 yes
GO:0006364 rRNA processing 1.8018 8 yes
GO:0007093 mitotic cell cycle checkpoint signaling 1.8018 4 yes
GO:0009952 anterior/posterior pattern specification 1.8018 4 yes
GO:0016072 rRNA metabolic process 1.8018 7 yes
GO:0016233 telomere capping 1.8018 6 yes
GO:0016444 somatic cell DNA recombination 1.8018 6 yes
GO:0016447 somatic recombination of immunoglobulin gene segments 1.8018 4 yes
GO:0031571 mitotic G1 DNA damage checkpoint signaling 1.8018 6 yes
GO:0033151 V(D)J recombination 1.8018 4 yes
GO:0033152 immunoglobulin V(D)J recombination 1.8018 5 yes
GO:0033153 T cell receptor V(D)J recombination 1.8018 5 yes
GO:0034462 small-subunit processome assembly 1.8018 7 yes
GO:0035282 segmentation 1.8018 4 yes
GO:0044773 mitotic DNA damage checkpoint signaling 1.8018 6 yes
GO:0044774 mitotic DNA integrity checkpoint signaling 1.8018 5 yes
GO:0044819 mitotic G1/S transition checkpoint signaling 1.8018 5 yes
GO:0045639 positive regulation of myeloid cell differentiation 1.8018 6 yes
GO:0045648 positive regulation of erythrocyte differentiation 1.8018 7 yes
GO:0097681 double-strand break repair via alternative nonhomologous end joining 1.8018 8 yes
GO:1905219 regulation of platelet formation 1.8018 6 yes
GO:1905221 positive regulation of platelet formation 1.8018 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in PRKDC_HUMAN
DOID:0050686 organ system cancer 4.5045 3 no
DOID:1289 neurodegenerative disease 3.6036 4 no
DOID:331 central nervous system disease 3.6036 3 no
DOID:193 reproductive organ cancer 2.7027 4 no
DOID:114 heart disease 2.7027 3 no
DOID:0111961 immunodeficiency 26 1.8018 6 yes
DOID:0111962 combined immunodeficiency 1.8018 4 yes
DOID:612 primary immunodeficiency disease 1.8018 3 yes
DOID:627 severe combined immunodeficiency 1.8018 5 yes
DOID:231 motor neuron disease 1.8018 5 no
DOID:0050539 Charcot-Marie-Tooth disease type 2 1.8018 7 no
DOID:10595 Charcot-Marie-Tooth disease 1.8018 6 no
DOID:440 neuromuscular disease 1.8018 5 no
DOID:574 peripheral nervous system disease 1.8018 3 no
DOID:870 neuropathy 1.8018 4 no
DOID:120 female reproductive organ cancer 1.8018 5 no
DOID:6457 Cowden syndrome 1.8018 3 no
DOID:0050700 cardiomyopathy 1.8018 4 no
DOID:0060036 intrinsic cardiomyopathy 1.8018 5 no
DOID:0080000 muscular disease 1.8018 3 no
DOID:12930 dilated cardiomyopathy 1.8018 6 no
DOID:423 myopathy 1.8018 5 no
DOID:66 muscle tissue disease 1.8018 4 no
DOID:10283 prostate cancer 1.8018 6 no
DOID:3856 male reproductive organ cancer 1.8018 5 no
DOID:65 connective tissue disease 1.8018 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DEAF1_HUMAN [view interactions] Low throughput no yes
ZBT7A_HUMAN [view interactions] Low throughput no yes
BRCA1_HUMAN [view interactions] Low throughput no yes
RN146_HUMAN [view interactions] Low throughput no yes
PELI1_HUMAN [view interactions] Low throughput no yes
AAPK2_HUMAN [view interactions] Low throughput no yes
FACD2_HUMAN [view interactions] Low throughput no no
TELO2_HUMAN [view interactions] Low throughput no yes
ESR1_HUMAN [view interactions] Low throughput no no
ILF2_HUMAN [view interactions] Low throughput no yes
EGFR_HUMAN [view interactions] Low throughput no no
H2AX_HUMAN [view interactions] Low throughput no yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
SIN1_HUMAN [view interactions] Low throughput no yes
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
IBP3_HUMAN [view interactions] Low throughput no no
MED13_HUMAN [view interactions] Low throughput no no
CDK8_HUMAN [view interactions] Low throughput no no
JUN_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
DNLI4_HUMAN [view interactions] Low throughput no yes
IFFO1_HUMAN [view interactions] Low throughput no yes
ZIC2_HUMAN [view interactions] Low throughput no no
GOLP3_HUMAN [view interactions] Low throughput no no
NEMO_HUMAN [view interactions] Low throughput no yes
MYC_HUMAN [view interactions] Low throughput no yes
H31_HUMAN [view interactions] Low throughput no yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
C1D_HUMAN [view interactions] Low throughput no yes
CIB1_HUMAN [view interactions] Low throughput no no
NCOA6_HUMAN [view interactions] Low throughput no yes
RFA2_HUMAN [view interactions] Low throughput no yes
WRN_HUMAN [view interactions] Low throughput no yes
ILF3_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
VIGLN_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR6_HUMAN [view interactions] Low throughput no yes
NR1H4_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
HDAC6_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
AICDA_HUMAN [view interactions] Low throughput no no
DHX9_HUMAN [view interactions] Low throughput no yes
XRCC4_HUMAN [view interactions] Low throughput no yes
THA_HUMAN [view interactions] Low throughput no yes
THB_HUMAN [view interactions] Low throughput no no
BIRC5_HUMAN [view interactions] Low throughput no no
BMI1_HUMAN [view interactions] Low throughput no yes
PP6R2_HUMAN [view interactions] Low throughput no no
PP6R3_HUMAN [view interactions] Low throughput no yes
MRE11_HUMAN [view interactions] Low throughput no yes
CHK1_HUMAN [view interactions] Low throughput no no
MSH6_HUMAN [view interactions] Low throughput no yes
MDC1_HUMAN [view interactions] Low throughput no yes
USF1_HUMAN [view interactions] Low throughput no yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
ARHG6_HUMAN [view interactions] Low throughput no no
AKT2_HUMAN [view entry] [view interactions] Low throughput yes yes
RFA1_HUMAN [view interactions] Low throughput no yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKA_HUMAN [view interactions] Low throughput no yes
LYN_HUMAN [view entry] [view interactions] Low throughput yes no
PRGR_HUMAN [view interactions] Low throughput no no
HSF1_HUMAN [view interactions] Low throughput no yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
ETS1_HUMAN [view interactions] Low throughput no no
SPI1_HUMAN [view interactions] Low throughput no no
ETV1_HUMAN [view interactions] Low throughput no no
KAT2A_HUMAN [view interactions] Low throughput no no
IKKB_HUMAN [view interactions] Low throughput no yes
NCF1_HUMAN [view interactions] Low throughput no no
TTI1_HUMAN [view interactions] Low throughput no yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
NCF2_HUMAN [view interactions] Low throughput no no
NCF4_HUMAN [view interactions] Low throughput no no
LRRK2_HUMAN [view interactions] Low throughput no yes
MK08_HUMAN [view interactions] Low throughput no yes
PO2F1_HUMAN [view interactions] Low throughput no yes
PPP6_HUMAN [view interactions] Low throughput no yes
PDX1_HUMAN [view interactions] Low throughput no no
HDAC3_HUMAN [view interactions] Low throughput no yes
H11_HUMAN [view interactions] Low throughput no no
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
PRKDC_HUMAN [view entry] [view interactions] Low throughput yes yes
SP1_HUMAN [view interactions] Low throughput no yes
CTDP1_HUMAN [view interactions] Low throughput no yes
RUVB2_HUMAN [view interactions] Low throughput no yes
R144A_HUMAN [view interactions] Low throughput no yes
ROA1_HUMAN [view entry] [view interactions] Low throughput yes yes
HNRPC_HUMAN [view interactions] Low throughput no yes
XRCC5_HUMAN [view interactions] Low throughput no yes
DCAF1_HUMAN [view interactions] Low throughput no yes
XRCC6_HUMAN [view interactions] Low throughput no yes
MBP_HUMAN [view entry] [view interactions] Low throughput yes no
PP6R1_HUMAN [view interactions] Low throughput no no
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
GSK3A_HUMAN [view interactions] Low throughput no yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
GRAB_HUMAN [view interactions] Low throughput no no
ANC2_HUMAN [view interactions] Low throughput no no
CASP3_HUMAN [view interactions] Low throughput no yes
FZR1_HUMAN [view interactions] Low throughput no no
4EBP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CCNB1_HUMAN [view interactions] Low throughput no no
CHK2_HUMAN [view interactions] Low throughput no yes
DCR1C_HUMAN [view interactions] Low throughput no no
FUMH_HUMAN [view entry] [view interactions] Low throughput yes yes
LOX15_HUMAN [view interactions] Low throughput no no
AAKG1_HUMAN [view interactions] Low throughput no no
XPA_HUMAN [view interactions] Low throughput no yes
LMNA_HUMAN [view entry] [view interactions] Low throughput yes yes
XRCC1_HUMAN [view entry] [view interactions] Low throughput yes yes
FLNA_HUMAN [view entry] [view interactions] Low throughput yes no
AKTIP_HUMAN [view interactions] Low throughput no yes
IF2B_HUMAN [view interactions] Low throughput no yes
HIF1A_HUMAN [view interactions] Low throughput no no
NHEJ1_HUMAN [view interactions] Low throughput no yes
SRF_HUMAN [view interactions] Low throughput no yes
TOP1_HUMAN [view interactions] Low throughput no yes
HXB7_HUMAN [view interactions] Low throughput no yes
TYY1_HUMAN [view interactions] Low throughput no yes
ERG_HUMAN [view interactions] Low throughput no yes
HDGF_HUMAN [view interactions] Low throughput no yes
PPE1_HUMAN [view interactions] High throughput no no
GRWD1_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP18_HUMAN [view interactions] High throughput no yes
B2L14_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
M4A4A_HUMAN [view interactions] High throughput no no
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
TF7L2_HUMAN [view interactions] High throughput no yes
TCTP_HUMAN [view entry] [view interactions] High throughput yes yes
TN13B_HUMAN [view interactions] High throughput no no
TM41B_HUMAN [view interactions] High throughput no yes
UN93B_HUMAN [view interactions] High throughput no yes
P2RY6_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
UCHL3_HUMAN [view interactions] High throughput no yes
AUP1_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
FAF2_HUMAN [view interactions] High throughput no yes
TRI29_HUMAN [view interactions] High throughput no no
FXRD2_HUMAN [view interactions] High throughput no yes
HDAC2_HUMAN [view interactions] High throughput no yes
UBAC2_HUMAN [view interactions] High throughput no yes
CTCF_HUMAN [view interactions] High throughput no yes
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
ATX3_HUMAN [view interactions] High throughput no yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
VRK1_HUMAN [view interactions] High throughput no yes
KAPCG_HUMAN [view interactions] High throughput no no
S15A3_HUMAN [view interactions] High throughput no yes
MK04_HUMAN [view interactions] High throughput no no
GRK6_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
IRAK1_HUMAN [view interactions] High throughput no yes
DUS2_HUMAN [view interactions] High throughput no no
PLK1_HUMAN [view interactions] High throughput no yes
PTPRU_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
KC1G2_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
MYLK_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
STYK1_HUMAN [view interactions] High throughput no yes
NFX1_HUMAN [view interactions] High throughput no yes
ADCK2_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
ST32C_HUMAN [view entry] [view interactions] High throughput yes yes
BRD7_HUMAN [view interactions] High throughput no yes
COQ8A_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
KPSH2_HUMAN [view interactions] High throughput no no
SET1A_HUMAN [view interactions] High throughput no yes
PMYT1_HUMAN [view interactions] High throughput no no
YAP1_HUMAN [view interactions] High throughput no yes
LATS2_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
NRBP2_HUMAN [view interactions] High throughput no yes
RPKL1_HUMAN [view interactions] High throughput no yes
HELLS_HUMAN [view interactions] High throughput no yes
SG196_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
EMC5_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
MN1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
SNIP1_HUMAN [view interactions] High throughput no no
ANR55_HUMAN [view interactions] High throughput no yes
DDR2_HUMAN [view interactions] High throughput no no
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SMC1A_HUMAN [view interactions] High throughput no yes
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR2_HUMAN [view interactions] High throughput no yes
STAG2_HUMAN [view interactions] High throughput no yes
VGFR3_HUMAN [view interactions] High throughput no yes
PDS5A_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
CDCA5_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
UBR5_HUMAN [view interactions] High throughput no no
PGFRB_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
TYRO3_HUMAN [view interactions] High throughput no yes
LRC31_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
SNW1_HUMAN [view interactions] High throughput no yes
CHM4C_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
EP300_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
CIC_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
F16P1_HUMAN [view interactions] High throughput no no
LITD1_HUMAN [view interactions] High throughput no no
CTIP_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
KDF1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
MKNK1_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
IKBE_HUMAN [view entry] [view interactions] High throughput yes yes
WDR5_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
M3K3_HUMAN [view interactions] High throughput no no
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
NFKB2_HUMAN [view interactions] High throughput no yes
PBIP1_HUMAN [view entry] [view interactions] High throughput yes no
RELB_HUMAN [view interactions] High throughput no yes
PTH2R_HUMAN [view interactions] High throughput no no
RIPK3_HUMAN [view interactions] High throughput no no
LRC25_HUMAN [view interactions] High throughput no yes
TNR1A_HUMAN [view interactions] High throughput no yes
MAS_HUMAN [view interactions] High throughput no no
TNR1B_HUMAN [view interactions] High throughput no no
ACM4_HUMAN [view entry] [view interactions] High throughput yes yes
TRADD_HUMAN [view interactions] High throughput no yes
DRD4_HUMAN [view entry] [view interactions] High throughput yes no
CD80_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
HUMMR_HUMAN [view interactions] High throughput no yes
CBX3_HUMAN [view interactions] High throughput no yes
KI2L4_HUMAN [view interactions] High throughput no no
TTI2_HUMAN [view interactions] High throughput no yes
VASN_HUMAN [view interactions] High throughput no yes
PHKG2_HUMAN [view interactions] High throughput no no
NKG2D_HUMAN [view interactions] High throughput no no
CSN5_HUMAN [view interactions] High throughput no yes
CRLF2_HUMAN [view interactions] High throughput no no
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
FPR1_HUMAN [view interactions] High throughput no no
NFKB1_HUMAN [view interactions] High throughput no yes
HIDE1_HUMAN [view interactions] High throughput no no
JMY_HUMAN [view interactions] High throughput no yes
ADA11_HUMAN [view entry] [view interactions] High throughput yes yes
RAB1A_HUMAN [view entry] [view interactions] High throughput yes yes
GPR17_HUMAN [view interactions] High throughput no no
RAB9B_HUMAN [view interactions] High throughput no yes
MAGA8_HUMAN [view interactions] High throughput no no
CENPA_HUMAN [view interactions] High throughput no no
MTLR_HUMAN [view interactions] High throughput no no
CC018_HUMAN [view interactions] High throughput no yes
H2A1_HUMAN [view interactions] High throughput no yes
IDD_HUMAN [view interactions] High throughput no no
H2AZ_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
TIFAB_HUMAN [view interactions] High throughput no no
EFNA4_HUMAN [view interactions] High throughput no no
KATIP_HUMAN [view interactions] High throughput no yes
P2Y10_HUMAN [view interactions] High throughput no no
CCNC_HUMAN [view interactions] High throughput no yes
I13R2_HUMAN [view interactions] High throughput no no
AN32E_HUMAN [view interactions] High throughput no yes
CSTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ACM3_HUMAN [view entry] [view interactions] High throughput yes yes
DYRK2_HUMAN [view interactions] High throughput no yes
S22AF_HUMAN [view interactions] High throughput no yes
UFO_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
FGFR3_HUMAN [view interactions] High throughput no yes
GPC5D_HUMAN [view interactions] High throughput no yes
VGFR1_HUMAN [view interactions] High throughput no no
NK3R_HUMAN [view interactions] High throughput no no
FLT3_HUMAN [view interactions] High throughput no no
NPY2R_HUMAN [view interactions] High throughput no no
VGFR2_HUMAN [view interactions] High throughput no no
F234A_HUMAN [view interactions] High throughput no yes
LMTK1_HUMAN [view interactions] High throughput no yes
S15A1_HUMAN [view interactions] High throughput no no
LMTK2_HUMAN [view entry] [view interactions] High throughput yes yes
OPALI_HUMAN [view interactions] High throughput no yes
MERTK_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
RON_HUMAN [view interactions] High throughput no yes
DTX3_HUMAN [view interactions] High throughput no yes
ROS1_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
TIE2_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
TMPS2_HUMAN [view interactions] High throughput no no
TOP3B_HUMAN [view interactions] High throughput no no
CATL1_HUMAN [view interactions] High throughput no yes
CATB_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
CATS_HUMAN [view interactions] High throughput no no
DPP4_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
RECQ5_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
MLH1_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
PMS2_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
CLC4E_HUMAN [view interactions] High throughput no no
UHRF2_HUMAN [view interactions] High throughput no no
MGMT_HUMAN [view interactions] High throughput no no
CUL1_HUMAN [view interactions] High throughput no yes
DGCR8_HUMAN [view entry] [view interactions] High throughput yes yes
ZEB1_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
H12_HUMAN [view interactions] High throughput no yes
RHOF_HUMAN [view interactions] High throughput no no
ANR28_HUMAN [view interactions] High throughput no no
KAT8_HUMAN [view interactions] High throughput no no
FKBP5_HUMAN [view interactions] High throughput no yes
MS3L1_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
H2B2E_HUMAN [view interactions] High throughput no yes
HMGA1_HUMAN [view interactions] High throughput no yes
MAP4_HUMAN [view entry] [view interactions] High throughput yes no
NUCKS_HUMAN [view interactions] High throughput no yes
CAF1A_HUMAN [view interactions] High throughput no yes
SP16H_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
TEBP_HUMAN [view interactions] High throughput no yes
SC61B_HUMAN [view interactions] High throughput no yes
SSRP1_HUMAN [view interactions] High throughput no yes
H33_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view interactions] High throughput no no
RIR2_HUMAN [view interactions] High throughput no no
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
THEM6_HUMAN [view interactions] High throughput no no
CDK4_HUMAN [view interactions] High throughput no no
PIDD1_HUMAN [view interactions] High throughput no yes
TSPO_HUMAN [view interactions] High throughput no yes
RAD21_HUMAN [view interactions] High throughput no yes
MPIP1_HUMAN [view interactions] High throughput no no
SMRCD_HUMAN [view interactions] High throughput no yes
LTC4S_HUMAN [view interactions] High throughput no no
NBN_HUMAN [view interactions] High throughput no yes
EDA_HUMAN [view interactions] High throughput no no
DCK_HUMAN [view interactions] High throughput no no
UBP7_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
MTR1B_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A2_HUMAN [view interactions] High throughput no yes
SAP25_HUMAN [view interactions] High throughput no no
SIR7_HUMAN [view interactions] High throughput no yes
BCAT2_HUMAN [view interactions] High throughput no no
MPIP2_HUMAN [view interactions] High throughput no no
AIRE_HUMAN [view interactions] High throughput no no
CEBPB_HUMAN [view interactions] High throughput no no
SSR4_HUMAN [view interactions] High throughput no no
TOP2A_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
DCXR_HUMAN [view interactions] High throughput no no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
PIM1_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
PA24C_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
JAK3_HUMAN [view interactions] High throughput no no
GBRL1_HUMAN [view interactions] High throughput no yes
GRK5_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
F264_HUMAN [view interactions] High throughput no no
AAKB2_HUMAN [view interactions] High throughput no yes
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
CHD1_HUMAN [view interactions] High throughput no yes
NIPS2_HUMAN [view interactions] High throughput no yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
CLN3_HUMAN [view interactions] High throughput no no
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
KKCC2_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
DDA1_HUMAN [view interactions] High throughput no yes
ATGA1_HUMAN [view interactions] High throughput no yes
ELP1_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view interactions] High throughput no yes
BECN1_HUMAN [view interactions] High throughput no yes
ATRIP_HUMAN [view interactions] High throughput no yes
ATG4C_HUMAN [view interactions] High throughput no yes
PNKP_HUMAN [view interactions] High throughput no yes
ITB1_HUMAN [view entry] [view interactions] High throughput yes no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
FINC_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
NOS2_HUMAN [view interactions] High throughput no yes
NPHP4_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
IQCB1_HUMAN [view interactions] High throughput no no
PAN2_HUMAN [view interactions] High throughput no no
TF2L1_HUMAN [view interactions] High throughput no yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
HDA11_HUMAN [view interactions] High throughput no no
RFA3_HUMAN [view interactions] High throughput no yes
ASB5_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
LGR4_HUMAN [view interactions] High throughput no yes
STF1_HUMAN [view interactions] High throughput no no
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
ILK_HUMAN [view interactions] High throughput no no
EMD_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
TF65_HUMAN [view entry] [view interactions] High throughput yes yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
POTE1_HUMAN [view interactions] High throughput no no
SKI_HUMAN [view interactions] High throughput no yes
TERF1_HUMAN [view interactions] High throughput no no
CRY1_HUMAN [view interactions] High throughput no yes
TINF2_HUMAN [view interactions] High throughput no no
CRY2_HUMAN [view interactions] High throughput no yes
DNJC7_HUMAN [view interactions] High throughput no yes
DCR1B_HUMAN [view interactions] High throughput no no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
UBC9_HUMAN [view interactions] High throughput no yes
NOTC1_HUMAN [view interactions] High throughput no yes
MEX3C_HUMAN [view interactions] High throughput no yes
CLK1_HUMAN [view interactions] High throughput no yes
LPAR4_HUMAN [view interactions] High throughput no no
PO5F1_HUMAN [view interactions] High throughput no yes
EPHA1_HUMAN [view interactions] High throughput no yes
CHD1L_HUMAN [view interactions] High throughput no yes
AHSA1_HUMAN [view entry] [view interactions] High throughput yes yes
AP1B1_HUMAN [view entry] [view interactions] High throughput yes yes
NFAC2_HUMAN [view interactions] High throughput no yes
E4F1_HUMAN [view interactions] High throughput no yes
RAD17_HUMAN [view interactions] High throughput no yes
MTG8R_HUMAN [view interactions] High throughput no yes
ATOH1_HUMAN [view interactions] High throughput no no
RASF1_HUMAN [view interactions] High throughput no yes
RRP1B_HUMAN [view interactions] High throughput no yes
NKX21_HUMAN [view interactions] High throughput no no
MTA70_HUMAN [view interactions] High throughput no no
MET14_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
CDC73_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
SF3B6_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
CWC27_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
THOC6_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
YBOX1_HUMAN [view interactions] High throughput no yes
PTN12_HUMAN [view interactions] High throughput no yes
MTF1_HUMAN [view interactions] High throughput no no
TRA2B_HUMAN [view interactions] High throughput no yes
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
LNX1_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
ELK1_HUMAN [view interactions] High throughput no yes
RBM25_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
ZN598_HUMAN [view interactions] High throughput no no
PRP16_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
BMR1A_HUMAN [view interactions] High throughput no no
SRP14_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
CDK9_HUMAN [view interactions] High throughput no yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP3_HUMAN [view interactions] High throughput no yes
DPOD1_HUMAN [view interactions] High throughput no yes
SMCA5_HUMAN [view interactions] High throughput no yes
NCBP1_HUMAN [view interactions] High throughput no yes
TXTP_HUMAN [view entry] [view interactions] High throughput yes no
SRS10_HUMAN [view interactions] High throughput no yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
KC1A_HUMAN [view interactions] High throughput no yes
SRP54_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
SERA_HUMAN [view entry] [view interactions] High throughput yes yes
PAXX_HUMAN [view interactions] High throughput no yes
B2CL1_HUMAN [view interactions] High throughput no yes
RBP2_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
COPE_HUMAN [view interactions] High throughput no yes
PTER_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
THYN1_HUMAN [view interactions] High throughput no yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
TGFB1_HUMAN [view interactions] High throughput no no
TPR_HUMAN [view interactions] High throughput no yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
EGLN3_HUMAN [view interactions] High throughput no no
PYRG2_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
RMD5A_HUMAN [view interactions] High throughput no yes
GTF2I_HUMAN [view interactions] High throughput no yes
TIAM2_HUMAN [view interactions] High throughput no yes
LAP2A_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
PWP2B_HUMAN [view interactions] High throughput no yes
TPTE_HUMAN [view interactions] High throughput no no
RTRAF_HUMAN [view interactions] High throughput no yes
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
PRP8_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
F161A_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
EHD1_HUMAN [view entry] [view interactions] High throughput yes no
SYNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
AAR2_HUMAN [view interactions] High throughput no no
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
CBPN_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
LRRF1_HUMAN [view interactions] High throughput no yes
ZN840_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
TRMB_HUMAN [view interactions] High throughput no yes
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
CHD3_HUMAN [view interactions] High throughput no yes
NUCB1_HUMAN [view interactions] High throughput no yes
LAMC3_HUMAN [view interactions] High throughput no no
CHD4_HUMAN [view interactions] High throughput no yes
RFC2_HUMAN [view interactions] High throughput no yes
SYNE2_HUMAN [view interactions] High throughput no no
UB2R1_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
TBC28_HUMAN [view interactions] High throughput no no
SPDLY_HUMAN [view interactions] High throughput no yes
THADA_HUMAN [view interactions] High throughput no yes
RNF8_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
NUP85_HUMAN [view interactions] High throughput no yes
GTPB4_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
LARP7_HUMAN [view interactions] High throughput no yes
NUP35_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
RN123_HUMAN [view interactions] High throughput no yes
WWP1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
Z3H7A_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
APLF_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
RN183_HUMAN [view interactions] High throughput no no
DCPS_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
WDR76_HUMAN [view interactions] High throughput no no
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
H4_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
E2F3_HUMAN [view interactions] High throughput no no
H2B1B_HUMAN [view interactions] High throughput no yes
RARA_HUMAN [view interactions] High throughput no no
H2A1B_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
CK5P2_HUMAN [view interactions] High throughput no yes
SWAP1_HUMAN [view interactions] Computational no no
MSH2_HUMAN [view interactions] Computational no yes
RN168_HUMAN [view interactions] Computational no no
DPOLM_HUMAN [view interactions] Computational no no
DPOLL_HUMAN [view interactions] Computational no no
APTX_HUMAN [view interactions] Computational no yes
RAD50_HUMAN [view interactions] Computational no yes
XPC_HUMAN [view interactions] Computational no yes
PF21A_HUMAN [view interactions] Computational no yes
STING_HUMAN [view interactions] Computational no yes
KDM1A_HUMAN [view interactions] Computational no yes
ATP23_HUMAN [view interactions] Computational no yes
TBK1_HUMAN [view entry] [view interactions] Computational yes yes
ERCC1_HUMAN [view interactions] Computational no yes
RD23B_HUMAN [view interactions] Computational no yes
MSH3_HUMAN [view interactions] Computational no no
TP53B_HUMAN [view entry] [view interactions] Computational yes yes
AKT3_HUMAN [view interactions] Computational no yes
RCOR1_HUMAN [view interactions] Computational no yes
CDN2D_HUMAN [view interactions] Computational no no
MDM2_HUMAN [view interactions] Computational no yes
ZSWM7_HUMAN [view interactions] Computational no no
CETN2_HUMAN [view interactions] Computational no yes
TDT_HUMAN [view interactions] Computational no no
XPF_HUMAN [view interactions] Computational no yes
TYDP1_HUMAN [view interactions] Computational no no
TYDP2_HUMAN [view interactions] Computational no no
BARD1_HUMAN [view interactions] Computational no yes
PAXI1_HUMAN [view interactions] Computational no no
IRF3_HUMAN [view interactions] Computational no yes