Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PP2AA_HUMAN

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I . Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at Ser-259 (PubMed). Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in PP2AA_HUMAN
GO:0017076 purine nucleotide binding 33.8129 4 no
GO:0032555 purine ribonucleotide binding 33.0935 4 no
GO:0035639 purine ribonucleoside triphosphate binding 33.0935 4 no
GO:0030554 adenyl nucleotide binding 28.0576 5 no
GO:0005524 ATP binding 27.3381 5 no
GO:0032559 adenyl ribonucleotide binding 27.3381 5 no
GO:0019900 kinase binding 23.7410 4 no
GO:0019901 protein kinase binding 21.5827 5 no
GO:0046872 metal ion binding 20.8633 4 yes
GO:0016791 phosphatase activity 10.0719 5 yes
GO:0042578 phosphoric ester hydrolase activity 10.0719 4 yes
GO:0004722 protein serine/threonine phosphatase activity 8.6331 4 yes
GO:0046982 protein heterodimerization activity 5.0360 4 yes
GO:0048156 tau protein binding 4.3165 4 yes
GO:0004725 protein tyrosine phosphatase activity 2.8777 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PP2AA_HUMAN
GO:0060255 regulation of macromolecule metabolic process 71.2230 4 yes
GO:0048522 positive regulation of cellular process 69.0647 4 yes
GO:0080090 regulation of primary metabolic process 68.3453 4 yes
GO:0031323 regulation of cellular metabolic process 66.9065 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 66.9065 4 yes
GO:0009893 positive regulation of metabolic process 56.1151 4 yes
GO:0048523 negative regulation of cellular process 55.3957 4 yes
GO:0051128 regulation of cellular component organization 54.6763 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 53.2374 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 51.7986 5 yes
GO:0051246 regulation of protein metabolic process 51.7986 5 yes
GO:0010646 regulation of cell communication 51.0791 4 yes
GO:0031325 positive regulation of cellular metabolic process 50.3597 5 yes
GO:0010468 regulation of gene expression 49.6403 5 yes
GO:0009889 regulation of biosynthetic process 48.2014 4 yes
GO:0031326 regulation of cellular biosynthetic process 48.2014 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 46.0432 5 yes
GO:0009966 regulation of signal transduction 43.1655 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 42.4460 5 yes
GO:0019220 regulation of phosphate metabolic process 41.7266 6 yes
GO:0051174 regulation of phosphorus metabolic process 41.7266 5 yes
GO:0051247 positive regulation of protein metabolic process 40.2878 6 yes
GO:0031399 regulation of protein modification process 39.5683 6 yes
GO:0051049 regulation of transport 37.4101 4 no
GO:0009892 negative regulation of metabolic process 36.6906 4 yes
GO:0042325 regulation of phosphorylation 35.9712 7 yes
GO:0010605 negative regulation of macromolecule metabolic process 35.2518 5 yes
GO:0036211 protein modification process 34.5324 4 yes
GO:0043412 macromolecule modification 34.5324 4 yes
GO:0051252 regulation of RNA metabolic process 34.5324 5 yes
GO:0009891 positive regulation of biosynthetic process 33.0935 5 no
GO:0031328 positive regulation of cellular biosynthetic process 33.0935 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 33.0935 6 no
GO:0048584 positive regulation of response to stimulus 33.0935 4 no
GO:0060341 regulation of cellular localization 33.0935 4 no
GO:0033043 regulation of organelle organization 32.3741 5 no
GO:0006996 organelle organization 32.3741 4 no
GO:0010647 positive regulation of cell communication 32.3741 5 no
GO:0023056 positive regulation of signaling 32.3741 4 no
GO:0001932 regulation of protein phosphorylation 31.6547 7 yes
GO:0006796 phosphate-containing compound metabolic process 31.6547 4 yes
GO:0031324 negative regulation of cellular metabolic process 31.6547 5 yes
GO:0043085 positive regulation of catalytic activity 31.6547 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 31.6547 5 yes
GO:0022607 cellular component assembly 31.6547 4 no
GO:0006355 regulation of DNA-templated transcription 30.9353 6 yes
GO:1903506 regulation of nucleic acid-templated transcription 30.9353 7 yes
GO:2001141 regulation of RNA biosynthetic process 30.9353 6 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 30.9353 6 no
GO:0051130 positive regulation of cellular component organization 30.9353 5 no
GO:1902531 regulation of intracellular signal transduction 30.2158 5 yes
GO:0008104 protein localization 30.2158 4 no
GO:0010941 regulation of cell death 30.2158 4 no
GO:0010562 positive regulation of phosphorus metabolic process 29.4964 6 yes
GO:0045937 positive regulation of phosphate metabolic process 29.4964 7 yes
GO:0051338 regulation of transferase activity 29.4964 4 yes
GO:0071310 cellular response to organic substance 29.4964 4 no
GO:0031401 positive regulation of protein modification process 28.7770 7 yes
GO:0045595 regulation of cell differentiation 28.7770 4 yes
GO:0032880 regulation of protein localization 28.0576 5 no
GO:0042327 positive regulation of phosphorylation 27.3381 8 yes
GO:0009967 positive regulation of signal transduction 27.3381 5 no
GO:0042981 regulation of apoptotic process 26.6187 6 no
GO:0043067 regulation of programmed cell death 26.6187 5 no
GO:1901701 cellular response to oxygen-containing compound 25.8993 4 no
GO:0042127 regulation of cell population proliferation 25.8993 4 no
GO:0048585 negative regulation of response to stimulus 25.1799 4 yes
GO:0001934 positive regulation of protein phosphorylation 24.4604 8 yes
GO:0051248 negative regulation of protein metabolic process 24.4604 6 yes
GO:0051336 regulation of hydrolase activity 24.4604 4 no
GO:0051254 positive regulation of RNA metabolic process 23.7410 6 no
GO:0051094 positive regulation of developmental process 23.7410 4 no
GO:0010648 negative regulation of cell communication 23.0216 5 yes
GO:0023057 negative regulation of signaling 23.0216 4 yes
GO:0050804 modulation of chemical synaptic transmission 23.0216 5 no
GO:0080134 regulation of response to stress 23.0216 4 no
GO:0099177 regulation of trans-synaptic signaling 23.0216 4 no
GO:0043549 regulation of kinase activity 22.3022 5 yes
GO:0010243 response to organonitrogen compound 22.3022 4 no
GO:0071702 organic substance transport 22.3022 4 no
GO:1903829 positive regulation of protein localization 22.3022 5 no
GO:0051347 positive regulation of transferase activity 21.5827 5 yes
GO:0010628 positive regulation of gene expression 21.5827 6 no
GO:0031344 regulation of cell projection organization 21.5827 5 no
GO:0045893 positive regulation of DNA-templated transcription 21.5827 7 no
GO:0051050 positive regulation of transport 21.5827 4 no
GO:0071705 nitrogen compound transport 21.5827 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.5827 6 no
GO:1902680 positive regulation of RNA biosynthetic process 21.5827 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 21.5827 8 no
GO:0060548 negative regulation of cell death 21.5827 5 no
GO:0043933 protein-containing complex organization 21.5827 4 no
GO:0009894 regulation of catabolic process 21.5827 4 no
GO:0070201 regulation of establishment of protein localization 20.8633 6 no
GO:0009968 negative regulation of signal transduction 20.1439 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 20.1439 7 no
GO:0051240 positive regulation of multicellular organismal process 20.1439 4 no
GO:0030030 cell projection organization 20.1439 4 no
GO:0044087 regulation of cellular component biogenesis 20.1439 4 no
GO:0045859 regulation of protein kinase activity 19.4245 6 yes
GO:0031400 negative regulation of protein modification process 18.7050 7 yes
GO:0010563 negative regulation of phosphorus metabolic process 17.2662 6 yes
GO:0030155 regulation of cell adhesion 17.2662 4 yes
GO:0045936 negative regulation of phosphate metabolic process 17.2662 7 yes
GO:0051726 regulation of cell cycle 17.2662 4 yes
GO:0051241 negative regulation of multicellular organismal process 16.5468 4 yes
GO:0006915 apoptotic process 15.8273 4 yes
GO:0033674 positive regulation of kinase activity 15.1079 6 yes
GO:0051052 regulation of DNA metabolic process 15.1079 5 yes
GO:0051093 negative regulation of developmental process 15.1079 4 yes
GO:0090304 nucleic acid metabolic process 15.1079 4 yes
GO:0042326 negative regulation of phosphorylation 13.6691 8 yes
GO:0071900 regulation of protein serine/threonine kinase activity 13.6691 7 yes
GO:0016070 RNA metabolic process 12.9496 5 yes
GO:0045596 negative regulation of cell differentiation 12.9496 5 yes
GO:0045860 positive regulation of protein kinase activity 12.2302 7 yes
GO:0001933 negative regulation of protein phosphorylation 11.5108 8 yes
GO:1902532 negative regulation of intracellular signal transduction 11.5108 6 yes
GO:0043393 regulation of protein binding 10.7914 4 yes
GO:0007346 regulation of mitotic cell cycle 10.0719 5 yes
GO:0010038 response to metal ion 10.0719 4 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 10.0719 8 yes
GO:0006470 protein dephosphorylation 9.3525 5 yes
GO:0016311 dephosphorylation 9.3525 5 yes
GO:0001558 regulation of cell growth 8.6331 4 yes
GO:0010564 regulation of cell cycle process 8.6331 5 yes
GO:0030111 regulation of Wnt signaling pathway 8.6331 5 yes
GO:0006396 RNA processing 7.9137 6 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 7.9137 8 yes
GO:1901987 regulation of cell cycle phase transition 6.4748 6 yes
GO:0045926 negative regulation of growth 5.7554 4 yes
GO:0008380 RNA splicing 5.0360 7 yes
GO:0019932 second-messenger-mediated signaling 5.0360 4 yes
GO:0051099 positive regulation of binding 5.0360 4 yes
GO:1901990 regulation of mitotic cell cycle phase transition 5.0360 6 yes
GO:0032092 positive regulation of protein binding 4.3165 5 yes
GO:0051896 regulation of protein kinase B signaling 4.3165 6 yes
GO:0010288 response to lead ion 3.5971 5 yes
GO:0010717 regulation of epithelial to mesenchymal transition 3.5971 5 yes
GO:0030308 negative regulation of cell growth 3.5971 5 yes
GO:0070262 peptidyl-serine dephosphorylation 3.5971 6 yes
GO:0035970 peptidyl-threonine dephosphorylation 2.8777 6 yes
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2.8777 9 yes
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2.8777 9 yes
GO:1902806 regulation of cell cycle G1/S phase transition 2.8777 7 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 2.8777 7 yes
GO:0043603 cellular amide metabolic process 2.1583 4 yes
GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2.1583 6 yes
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 2.1583 7 yes
GO:0051898 negative regulation of protein kinase B signaling 2.1583 7 yes
GO:1904892 regulation of receptor signaling pathway via STAT 2.1583 5 yes
GO:1904893 negative regulation of receptor signaling pathway via STAT 2.1583 6 yes
GO:0006275 regulation of DNA replication 1.4388 6 yes
GO:0006643 membrane lipid metabolic process 1.4388 4 yes
GO:0006665 sphingolipid metabolic process 1.4388 4 yes
GO:0006672 ceramide metabolic process 1.4388 5 yes
GO:0010719 negative regulation of epithelial to mesenchymal transition 1.4388 5 yes
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1.4388 8 yes

Disease

Term Name % Distance from top the of the tree Annotated in PP2AA_HUMAN
DOID:0050686 organ system cancer 2.8777 3 no
DOID:0060038 specific developmental disorder 1.4388 3 no
DOID:0060307 autosomal dominant intellectual developmental disorder 1.4388 5 no
DOID:1059 intellectual disability 1.4388 4 no
DOID:2978 carbohydrate metabolic disorder 1.4388 3 no
DOID:120 female reproductive organ cancer 1.4388 5 no
DOID:193 reproductive organ cancer 1.4388 4 no
DOID:0111962 combined immunodeficiency 1.4388 4 no
DOID:612 primary immunodeficiency disease 1.4388 3 no
DOID:627 severe combined immunodeficiency 1.4388 5 no
DOID:6457 Cowden syndrome 1.4388 3 no
DOID:0050700 cardiomyopathy 1.4388 4 no
DOID:0060036 intrinsic cardiomyopathy 1.4388 5 no
DOID:114 heart disease 1.4388 3 no
DOID:12930 dilated cardiomyopathy 1.4388 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
M3K3_HUMAN [view interactions] Low throughput no no
CCNG1_HUMAN [view interactions] Low throughput no yes
BTBDA_HUMAN [view interactions] Low throughput no no
AKT3_HUMAN [view interactions] Low throughput no yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
AURKB_HUMAN [view interactions] Low throughput no yes
NR1I3_HUMAN [view interactions] Low throughput no no
ADCY8_HUMAN [view entry] [view interactions] Low throughput yes yes
2AAA_HUMAN [view entry] [view interactions] Low throughput yes no
IGBP1_HUMAN [view interactions] Low throughput no yes
KISSR_HUMAN [view interactions] Low throughput no yes
PPP5_HUMAN [view entry] [view interactions] Low throughput yes yes
CTDP1_HUMAN [view interactions] Low throughput no yes
2A5B_HUMAN [view interactions] Low throughput no yes
ID1_HUMAN [view interactions] Low throughput no yes
2A5G_HUMAN [view interactions] Low throughput no yes
CAV1_HUMAN [view interactions] Low throughput no no
2A5A_HUMAN [view interactions] Low throughput no yes
DPOLA_HUMAN [view interactions] Low throughput no yes
ERN2_HUMAN [view interactions] Low throughput no yes
AMRA1_HUMAN [view interactions] Low throughput no yes
NXN_HUMAN [view interactions] Low throughput no no
2ABA_HUMAN [view interactions] Low throughput no yes
IEX1_HUMAN [view interactions] Low throughput no yes
2AAB_HUMAN [view interactions] Low throughput no yes
NKD1_HUMAN [view interactions] Low throughput no no
TTP_HUMAN [view interactions] Low throughput no yes
PPME1_HUMAN [view interactions] Low throughput no yes
SETBP_HUMAN [view interactions] Low throughput no yes
EP300_HUMAN [view interactions] Low throughput no yes
DAPK1_HUMAN [view entry] [view interactions] Low throughput yes yes
PHOCN_HUMAN [view interactions] Low throughput no yes
STRP1_HUMAN [view interactions] Low throughput no yes
2A5D_HUMAN [view entry] [view interactions] Low throughput yes yes
2A5E_HUMAN [view interactions] Low throughput no yes
2ABG_HUMAN [view interactions] Low throughput no yes
2ABD_HUMAN [view interactions] Low throughput no yes
PTPA_HUMAN [view interactions] Low throughput no yes
AXIN1_HUMAN [view interactions] Low throughput no yes
UBP7_HUMAN [view interactions] Low throughput no yes
MYC_HUMAN [view interactions] Low throughput no yes
CDC20_HUMAN [view interactions] Low throughput no no
NOSIP_HUMAN [view interactions] Low throughput no yes
P2R3B_HUMAN [view interactions] Low throughput no no
BCL10_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
STRN3_HUMAN [view interactions] Low throughput no yes
BRCA2_HUMAN [view interactions] Low throughput no no
CEBPA_HUMAN [view interactions] Low throughput no yes
AN32A_HUMAN [view interactions] Low throughput no yes
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
TIPRL_HUMAN [view interactions] Low throughput no yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
CASP8_HUMAN [view interactions] Low throughput no yes
ESPL1_HUMAN [view interactions] Low throughput no yes
TNF10_HUMAN [view interactions] Low throughput no no
P53_HUMAN [view interactions] Low throughput no no
FBX17_HUMAN [view interactions] Low throughput no no
RACK1_HUMAN [view interactions] Low throughput no yes
MDM2_HUMAN [view interactions] Low throughput no yes
BUB1B_HUMAN [view interactions] Low throughput no no
AKAP6_HUMAN [view interactions] Low throughput no no
STRP2_HUMAN [view interactions] Low throughput no yes
BRAF_HUMAN [view interactions] Low throughput no yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
NMD3A_HUMAN [view entry] [view interactions] Low throughput yes no
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
P2R3A_HUMAN [view interactions] Low throughput no yes
SET_HUMAN [view interactions] Low throughput no yes
CDC16_HUMAN [view interactions] Low throughput no yes
YDJC_HUMAN [view interactions] Low throughput no no
NCAM1_HUMAN [view entry] [view interactions] Low throughput yes no
NLRP3_HUMAN [view interactions] Low throughput no yes
LCMT1_HUMAN [view interactions] Low throughput no yes
IRF3_HUMAN [view interactions] Low throughput no yes
SGO1_HUMAN [view interactions] Low throughput no no
RBL2_HUMAN [view interactions] Low throughput no yes
RBL1_HUMAN [view interactions] Low throughput no yes
IKKB_HUMAN [view interactions] Low throughput no yes
NEMO_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
TWST1_HUMAN [view interactions] Low throughput no no
IER5_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
PSME3_HUMAN [view interactions] Low throughput no yes
AKTS1_HUMAN [view interactions] Low throughput no yes
BCL2_HUMAN [view interactions] Low throughput no no
SGO2_HUMAN [view interactions] Low throughput no no
KIF23_HUMAN [view interactions] Low throughput no yes
IF4E_HUMAN [view entry] [view interactions] Low throughput yes yes
DPYL2_HUMAN [view entry] [view interactions] Low throughput yes yes
AAPK1_HUMAN [view interactions] Low throughput no no
HUNK_HUMAN [view interactions] Low throughput no yes
COF1_HUMAN [view entry] [view interactions] Low throughput yes no
HDAC5_HUMAN [view interactions] Low throughput no yes
IKKA_HUMAN [view interactions] Low throughput no yes
SGK1_HUMAN [view interactions] Low throughput no yes
KCD20_HUMAN [view interactions] Low throughput no yes
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
AMOL2_HUMAN [view interactions] Low throughput no no
SIK2_HUMAN [view interactions] Low throughput no yes
CDK2_HUMAN [view interactions] Low throughput no yes
CDK6_HUMAN [view interactions] Low throughput no yes
FOXO3_HUMAN [view interactions] Low throughput no yes
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
H11_HUMAN [view interactions] Low throughput no no
PYGM_HUMAN [view entry] [view interactions] Low throughput yes no
KCC1A_HUMAN [view entry] [view interactions] Low throughput yes yes
PIM1_HUMAN [view interactions] Low throughput no yes
CAR11_HUMAN [view interactions] Low throughput no no
CHK2_HUMAN [view interactions] Low throughput no yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
TIF1B_HUMAN [view interactions] Low throughput no yes
MRCKB_HUMAN [view entry] [view interactions] Low throughput yes yes
TIAM1_HUMAN [view entry] [view interactions] Low throughput yes yes
RGAP1_HUMAN [view interactions] Low throughput no no
HD_HUMAN [view entry] [view interactions] Low throughput yes yes
M3K7_HUMAN [view interactions] Low throughput no yes
ARL2_HUMAN [view interactions] Low throughput no yes
H2AX_HUMAN [view interactions] Low throughput no yes
PPM1B_HUMAN [view interactions] Low throughput no yes
MK03_HUMAN [view entry] [view interactions] Low throughput yes yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
MKNK1_HUMAN [view interactions] Low throughput no yes
RYR1_HUMAN [view interactions] Low throughput no no
TLX1_HUMAN [view interactions] Low throughput no no
ERF1_HUMAN [view interactions] Low throughput no yes
TBCD_HUMAN [view entry] [view interactions] Low throughput yes no
KC1A_HUMAN [view interactions] Low throughput no yes
CCNG2_HUMAN [view entry] [view interactions] Low throughput yes yes
PAXI_HUMAN [view interactions] Low throughput no yes
BEST1_HUMAN [view interactions] Low throughput no no
SPY2_HUMAN [view interactions] Low throughput no yes
ROA2_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC7_HUMAN [view interactions] Low throughput no no
HDAC4_HUMAN [view interactions] Low throughput no yes
RAC1_HUMAN [view entry] [view interactions] Low throughput yes no
TRI18_HUMAN [view interactions] Low throughput no no
IRAK1_HUMAN [view interactions] Low throughput no yes
PABP1_HUMAN [view entry] [view interactions] Low throughput yes yes
BRCA1_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
MDC1_HUMAN [view interactions] High throughput no yes
PAXI1_HUMAN [view interactions] High throughput no no
KLH15_HUMAN [view interactions] High throughput no yes
SMUF1_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
BHE40_HUMAN [view interactions] High throughput no yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
RORG_HUMAN [view interactions] High throughput no no
RFA3_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
ERR2_HUMAN [view interactions] High throughput no no
ZN346_HUMAN [view interactions] High throughput no yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
UNC5B_HUMAN [view interactions] High throughput no yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
GRN_HUMAN [view interactions] High throughput no no
KNG1_HUMAN [view interactions] High throughput no no
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
FX4L6_HUMAN [view interactions] High throughput no no
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
LACC1_HUMAN [view interactions] High throughput no yes
PR14L_HUMAN [view interactions] High throughput no no
KS6B2_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
CP131_HUMAN [view interactions] High throughput no no
LIPA1_HUMAN [view entry] [view interactions] High throughput yes yes
HELLS_HUMAN [view interactions] High throughput no yes
SIKE1_HUMAN [view interactions] High throughput no yes
PRIC3_HUMAN [view interactions] High throughput no yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SSRG_HUMAN [view interactions] High throughput no yes
ATPK_HUMAN [view interactions] High throughput no yes
DOCK5_HUMAN [view entry] [view interactions] High throughput yes no
ZMY11_HUMAN [view interactions] High throughput no no
2ABB_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
SENP6_HUMAN [view interactions] High throughput no yes
ZFP91_HUMAN [view interactions] High throughput no yes
ING5_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
STRN_HUMAN [view entry] [view interactions] High throughput yes yes
LIPA3_HUMAN [view entry] [view interactions] High throughput yes yes
CDC27_HUMAN [view interactions] High throughput no yes
CEP43_HUMAN [view interactions] High throughput no no
CT2NL_HUMAN [view interactions] High throughput no yes
CTTB2_HUMAN [view entry] [view interactions] High throughput yes yes
TAFA3_HUMAN [view interactions] High throughput no no
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
COP1_HUMAN [view interactions] High throughput no no
SLMAP_HUMAN [view entry] [view interactions] High throughput yes yes
ZN785_HUMAN [view interactions] High throughput no no
LIPA2_HUMAN [view entry] [view interactions] High throughput yes no
TINAG_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
PDC10_HUMAN [view interactions] High throughput no yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
STK26_HUMAN [view interactions] High throughput no no
AKT2_HUMAN [view entry] [view interactions] High throughput yes yes
STK24_HUMAN [view interactions] High throughput no yes
STK25_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
T3JAM_HUMAN [view interactions] High throughput no no
CCND2_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
RMP_HUMAN [view interactions] High throughput no yes
FTM_HUMAN [view interactions] High throughput no yes
MAX_HUMAN [view interactions] High throughput no yes
EP400_HUMAN [view interactions] High throughput no yes
CBX5_HUMAN [view interactions] High throughput no yes
EPC1_HUMAN [view interactions] High throughput no no
VPS72_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
LRFN4_HUMAN [view entry] [view interactions] High throughput yes yes
US6NL_HUMAN [view interactions] High throughput no yes
FANCM_HUMAN [view interactions] High throughput no no
LSM11_HUMAN [view interactions] High throughput no yes
RM22_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
KEAP1_HUMAN [view interactions] High throughput no yes
COPE_HUMAN [view interactions] High throughput no yes
CA131_HUMAN [view interactions] High throughput no yes
GSK3A_HUMAN [view interactions] High throughput no yes
INT4_HUMAN [view interactions] High throughput no yes
DPOD1_HUMAN [view interactions] High throughput no yes
RT07_HUMAN [view interactions] High throughput no yes
ZN217_HUMAN [view interactions] High throughput no yes
ERI1_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
S18L2_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
RPP29_HUMAN [view entry] [view interactions] High throughput yes yes
AAR2_HUMAN [view interactions] High throughput no no
TFB2M_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
ZCHC9_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
INT12_HUMAN [view interactions] High throughput no yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
CCDC6_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
REQU_HUMAN [view interactions] High throughput no yes
TRIM5_HUMAN [view interactions] High throughput no yes
TM109_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
PP4R1_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
INT5_HUMAN [view interactions] High throughput no no
PP4C_HUMAN [view interactions] High throughput no yes
APC1_HUMAN [view interactions] High throughput no no
INT10_HUMAN [view interactions] High throughput no yes
APC4_HUMAN [view interactions] High throughput no yes
HEMH_HUMAN [view interactions] High throughput no yes
APC7_HUMAN [view interactions] High throughput no yes
FGOP2_HUMAN [view interactions] High throughput no yes
PKN3_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
NPTX1_HUMAN [view entry] [view interactions] High throughput yes yes
NHLC2_HUMAN [view interactions] High throughput no yes
VATD_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
RP9_HUMAN [view interactions] High throughput no yes
INT6_HUMAN [view interactions] High throughput no yes
PCM1_HUMAN [view interactions] High throughput no yes
DUS10_HUMAN [view entry] [view interactions] High throughput yes yes
NHSL1_HUMAN [view interactions] High throughput no yes
DUS9_HUMAN [view interactions] High throughput no no
ZN764_HUMAN [view interactions] High throughput no no
PTN7_HUMAN [view interactions] High throughput no no
ZN550_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
SRTD4_HUMAN [view interactions] High throughput no yes
FOXD4_HUMAN [view interactions] High throughput no no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
ZC3H1_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
CNDD3_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
ZN331_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
KLD8A_HUMAN [view interactions] High throughput no no
WDR86_HUMAN [view interactions] High throughput no no
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
TBCC1_HUMAN [view interactions] High throughput no no
FA13A_HUMAN [view interactions] High throughput no yes
ZN517_HUMAN [view interactions] High throughput no no
RHG31_HUMAN [view interactions] High throughput no yes
WNT7A_HUMAN [view entry] [view interactions] High throughput yes no
STA13_HUMAN [view interactions] High throughput no yes
LRC56_HUMAN [view interactions] High throughput no no
CHM4C_HUMAN [view interactions] High throughput no yes
ZN114_HUMAN [view interactions] High throughput no no
PRR14_HUMAN [view interactions] High throughput no no
NMRL1_HUMAN [view interactions] High throughput no yes
CDCA4_HUMAN [view interactions] High throughput no no
CUL4A_HUMAN [view interactions] High throughput no no
FOXS1_HUMAN [view interactions] High throughput no yes
NMDE1_HUMAN [view entry] [view interactions] High throughput yes yes
ANR39_HUMAN [view interactions] High throughput no no
NUDC1_HUMAN [view interactions] High throughput no no
S10A2_HUMAN [view interactions] High throughput no no
PRD16_HUMAN [view interactions] High throughput no no
COKA1_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
SRTD2_HUMAN [view interactions] High throughput no yes
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
ZSC18_HUMAN [view interactions] High throughput no yes
GRB10_HUMAN [view entry] [view interactions] High throughput yes yes
GREM2_HUMAN [view interactions] High throughput no no
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
VATG2_HUMAN [view entry] [view interactions] High throughput yes yes
FA13B_HUMAN [view interactions] High throughput no yes
FSP1_HUMAN [view interactions] High throughput no yes
CRBG1_HUMAN [view interactions] High throughput no no
DUS19_HUMAN [view interactions] High throughput no yes
RDH8_HUMAN [view interactions] High throughput no no
IBP5_HUMAN [view interactions] High throughput no no
FXL16_HUMAN [view interactions] High throughput no yes
CC142_HUMAN [view interactions] High throughput no no
WDR61_HUMAN [view interactions] High throughput no yes
CX066_HUMAN [view interactions] High throughput no no
UNG_HUMAN [view interactions] High throughput no yes
SRTD1_HUMAN [view interactions] High throughput no no
TTC33_HUMAN [view interactions] High throughput no yes
CA021_HUMAN [view interactions] High throughput no yes
TBCD4_HUMAN [view interactions] High throughput no yes
CI170_HUMAN [view interactions] High throughput no no
PBIR2_HUMAN [view interactions] High throughput no yes
AT7L1_HUMAN [view interactions] High throughput no yes
PBIR1_HUMAN [view interactions] High throughput no yes
IBP6_HUMAN [view interactions] High throughput no yes
ENSA_HUMAN [view interactions] High throughput no yes
E41L5_HUMAN [view interactions] High throughput no no
ARHG2_HUMAN [view entry] [view interactions] High throughput yes yes
TFPT_HUMAN [view interactions] High throughput no yes
ANKL2_HUMAN [view interactions] High throughput no yes
IER2_HUMAN [view interactions] High throughput no no
PP2AB_HUMAN [view interactions] High throughput no yes
WN10A_HUMAN [view interactions] High throughput no no
PTPC1_HUMAN [view interactions] High throughput no yes
F133A_HUMAN [view interactions] High throughput no no
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
PAAT_HUMAN [view interactions] High throughput no yes
TMM69_HUMAN [view interactions] High throughput no no
ISCA2_HUMAN [view interactions] High throughput no yes
PPR21_HUMAN [view interactions] High throughput no yes
MRM1_HUMAN [view interactions] High throughput no no
APLP2_HUMAN [view interactions] High throughput no yes
CGAT1_HUMAN [view interactions] High throughput no no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
DMAP1_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
PER1_HUMAN [view interactions] High throughput no no
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
STAM1_HUMAN [view interactions] High throughput no yes
INT2_HUMAN [view interactions] High throughput no yes
FA43A_HUMAN [view interactions] High throughput no no
SMCO3_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
INT14_HUMAN [view interactions] High throughput no yes
PTTG1_HUMAN [view interactions] High throughput no no
INT3_HUMAN [view interactions] High throughput no yes
INT7_HUMAN [view interactions] High throughput no no
ZN363_HUMAN [view interactions] High throughput no yes
INT9_HUMAN [view interactions] High throughput no no
INT1_HUMAN [view interactions] High throughput no yes
INT8_HUMAN [view interactions] High throughput no yes
NELFD_HUMAN [view interactions] High throughput no yes
INT11_HUMAN [view interactions] High throughput no yes
SPT5H_HUMAN [view interactions] High throughput no yes
B2L14_HUMAN [view interactions] High throughput no yes
RPAB4_HUMAN [view interactions] High throughput no no
HTRA4_HUMAN [view interactions] High throughput no no
RPAB1_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
RPB3_HUMAN [view interactions] High throughput no yes
KSYK_HUMAN [view interactions] High throughput no no
RPB1_HUMAN [view interactions] High throughput no no
MAST1_HUMAN [view interactions] High throughput no yes
LPP_HUMAN [view interactions] High throughput no yes
RPB2_HUMAN [view interactions] High throughput no yes
CEP78_HUMAN [view interactions] High throughput no yes
SOGA1_HUMAN [view interactions] High throughput no yes
INT13_HUMAN [view interactions] High throughput no no
RPB4_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
NELFA_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
P2R3C_HUMAN [view interactions] High throughput no yes
NELFB_HUMAN [view interactions] High throughput no no
CG026_HUMAN [view interactions] High throughput no yes
NCKP1_HUMAN [view entry] [view interactions] High throughput yes yes
ANGI_HUMAN [view interactions] High throughput no no
SOSSC_HUMAN [view interactions] High throughput no yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
LIPB1_HUMAN [view interactions] High throughput no yes
CYTSB_HUMAN [view entry] [view interactions] High throughput yes yes
PCH2_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
CDN2C_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
VAC14_HUMAN [view entry] [view interactions] High throughput yes yes
CC036_HUMAN [view interactions] High throughput no no
CLPP_HUMAN [view interactions] High throughput no yes
UBAP2_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
PTN_HUMAN [view entry] [view interactions] High throughput yes yes
M4K1_HUMAN [view interactions] High throughput no no
INO1_HUMAN [view interactions] High throughput no no
M4K4_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
M4K3_HUMAN [view interactions] High throughput no no
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
CUL1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
NOTC1_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
KATIP_HUMAN [view interactions] High throughput no yes
PRS10_HUMAN [view interactions] High throughput no yes
NUBP2_HUMAN [view interactions] High throughput no yes
ICLN_HUMAN [view interactions] High throughput no yes
PIN1_HUMAN [view entry] [view interactions] High throughput yes yes
SCHI1_HUMAN [view interactions] High throughput no yes
DOPD_HUMAN [view interactions] High throughput no yes
AHI1_HUMAN [view interactions] High throughput no yes
PIR_HUMAN [view interactions] High throughput no no
GLI2_HUMAN [view interactions] High throughput no yes
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
XRN1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
PSMD3_HUMAN [view interactions] High throughput no yes
NRDC_HUMAN [view interactions] High throughput no no
DEC1_HUMAN [view interactions] High throughput no no
SAHH2_HUMAN [view entry] [view interactions] High throughput yes yes
YPEL3_HUMAN [view interactions] High throughput no yes
ARPC4_HUMAN [view entry] [view interactions] High throughput yes no
TRI35_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBL3_HUMAN [view interactions] High throughput no yes
NIF3L_HUMAN [view interactions] High throughput no yes
BMR1B_HUMAN [view interactions] High throughput no no
PFD1_HUMAN [view interactions] High throughput no yes
LA_HUMAN [view interactions] High throughput no yes
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
TNPO3_HUMAN [view interactions] High throughput no yes
FNBP1_HUMAN [view interactions] High throughput no yes
PUR1_HUMAN [view interactions] High throughput no yes
PACS1_HUMAN [view entry] [view interactions] High throughput yes yes
PMS2_HUMAN [view interactions] High throughput no yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
NAA40_HUMAN [view interactions] High throughput no no
PRKDC_HUMAN [view entry] [view interactions] High throughput yes yes
TERF1_HUMAN [view interactions] High throughput no no
TBA8_HUMAN [view interactions] High throughput no yes
CE350_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
RALA_HUMAN [view entry] [view interactions] High throughput yes yes
SUMO2_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
NMDE2_HUMAN [view entry] [view interactions] High throughput yes no
CANB1_HUMAN [view entry] [view interactions] Computational yes yes
PP4R4_HUMAN [view interactions] Computational no yes
ULK1_HUMAN [view interactions] Computational no no
PP2BB_HUMAN [view entry] [view interactions] Computational yes yes
SC6A4_HUMAN [view entry] [view interactions] Computational yes no
MP2K1_HUMAN [view entry] [view interactions] Computational yes yes
CXCR2_HUMAN [view interactions] Computational no no
MYPT1_HUMAN [view entry] [view interactions] Computational yes yes
FRAT2_HUMAN [view interactions] Computational no no
FOXM1_HUMAN [view interactions] Computational no yes
CHK1_HUMAN [view interactions] Computational no no
NEPR1_HUMAN [view interactions] Computational no yes
ULK2_HUMAN [view interactions] Computational no yes
DVL3_HUMAN [view interactions] Computational no yes
LCK_HUMAN [view entry] [view interactions] Computational yes no
INSR_HUMAN [view interactions] Computational no yes
INS_HUMAN [view interactions] Computational no no
MARK3_HUMAN [view interactions] Computational no yes
TOX4_HUMAN [view interactions] Computational no yes
1433G_HUMAN [view entry] [view interactions] Computational yes yes
SMG5_HUMAN [view interactions] Computational no no
MLXPL_HUMAN [view interactions] Computational no no
PP1RA_HUMAN [view interactions] Computational no yes
PP4R2_HUMAN [view interactions] Computational no yes
SHOC2_HUMAN [view interactions] Computational no yes
PP6R3_HUMAN [view interactions] Computational no yes
FRAT1_HUMAN [view interactions] Computational no yes
1433T_HUMAN [view entry] [view interactions] Computational yes yes
LRP6_HUMAN [view interactions] Computational no yes
SMG7_HUMAN [view interactions] Computational no no
MP2K2_HUMAN [view entry] [view interactions] Computational yes yes
YES_HUMAN [view entry] [view interactions] Computational yes yes
4EBP1_HUMAN [view entry] [view interactions] Computational yes yes
PP2BA_HUMAN [view entry] [view interactions] Computational yes yes
PTN11_HUMAN [view entry] [view interactions] Computational yes yes
RASN_HUMAN [view entry] [view interactions] Computational yes no
1433S_HUMAN [view entry] [view interactions] Computational yes yes
FBX43_HUMAN [view interactions] Computational no no
1433F_HUMAN [view entry] [view interactions] Computational yes yes
MK07_HUMAN [view interactions] Computational no yes
PR15B_HUMAN [view interactions] Computational no no
TGFR2_HUMAN [view interactions] Computational no no
WNT3A_HUMAN [view entry] [view interactions] Computational yes no
PP1A_HUMAN [view entry] [view interactions] Computational yes yes
LYN_HUMAN [view entry] [view interactions] Computational yes no
DVL1_HUMAN [view entry] [view interactions] Computational yes yes
PPR1B_HUMAN [view entry] [view interactions] Computational yes yes
FZD2_HUMAN [view interactions] Computational no no
LRP5_HUMAN [view interactions] Computational no yes
PP1G_HUMAN [view entry] [view interactions] Computational yes yes
RASH_HUMAN [view entry] [view interactions] Computational yes no
CTNB1_HUMAN [view entry] [view interactions] Computational yes yes
IL8_HUMAN [view interactions] Computational no no
OCLN_HUMAN [view interactions] Computational no no
MTOR_HUMAN [view entry] [view interactions] Computational yes yes
BUB1_HUMAN [view interactions] Computational no no
FZD1_HUMAN [view interactions] Computational no yes
FYN_HUMAN [view entry] [view interactions] Computational yes no
PPR17_HUMAN [view interactions] Computational no no
WDR82_HUMAN [view interactions] Computational no no
REC8_HUMAN [view interactions] Computational no yes
PP1B_HUMAN [view entry] [view interactions] Computational yes yes
WNT1_HUMAN [view interactions] Computational no no
CYC_HUMAN [view entry] [view interactions] Computational yes yes
EGF_HUMAN [view interactions] Computational no no
WNT8B_HUMAN [view interactions] Computational no no
DVL2_HUMAN [view interactions] Computational no yes
CDK1_HUMAN [view interactions] Computational no no
KS6B1_HUMAN [view entry] [view interactions] Computational yes yes
STK3_HUMAN [view interactions] Computational no yes
RB_HUMAN [view interactions] Computational no yes
ARP19_HUMAN [view interactions] Computational no yes
SRC_HUMAN [view entry] [view interactions] Computational yes no
1433B_HUMAN [view entry] [view interactions] Computational yes yes
F261_HUMAN [view interactions] Computational no no
CNEP1_HUMAN [view interactions] Computational no yes
RENT1_HUMAN [view entry] [view interactions] Computational yes yes
ARRB1_HUMAN [view entry] [view interactions] Computational yes yes
BAF_HUMAN [view entry] [view interactions] Computational yes yes
ATGA1_HUMAN [view interactions] Computational no yes
GWL_HUMAN [view interactions] Computational no yes