COF1_HUMAN
Evidence for PS localization
Functions
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed). Required for the centralization of the mitotic spindle and symmetric division of zygotes . Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (PubMed). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed). Required for neural tube morphogenesis and neural crest cell migration . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in COF1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 34.2857 | 4 | no |
| GO:0000166 | nucleotide binding | 30.7143 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.7143 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 28.5714 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.1429 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 26.4286 | 6 | no |
| GO:0043169 | cation binding | 25.7143 | 4 | no |
| GO:0046872 | metal ion binding | 25.7143 | 5 | no |
| GO:0003723 | RNA binding | 25.7143 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 24.2857 | 5 | no |
| GO:0019900 | kinase binding | 23.5714 | 4 | no |
| GO:0003779 | actin binding | 22.8571 | 4 | yes |
| GO:0005524 | ATP binding | 22.8571 | 5 | no |
| GO:0019901 | protein kinase binding | 21.4286 | 5 | no |
| GO:0045296 | cadherin binding | 20.7143 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in COF1_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 60.7143 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 59.2857 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 56.4286 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.7143 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 52.8571 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 52.1429 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 47.8571 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 46.4286 | 5 | no |
| GO:0006996 | organelle organization | 45.7143 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.7143 | 5 | no |
| GO:0010646 | regulation of cell communication | 45.7143 | 4 | no |
| GO:0010468 | regulation of gene expression | 45.0000 | 6 | no |
| GO:0009893 | positive regulation of metabolic process | 42.1429 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.1429 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 38.5714 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 37.8571 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 37.1429 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 37.1429 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 35.0000 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 34.2857 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 34.2857 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 33.5714 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 33.5714 | 4 | yes |
| GO:0022607 | cellular component assembly | 33.5714 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.8571 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 31.4286 | 7 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.4286 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 31.4286 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.7143 | 5 | no |
| GO:0033043 | regulation of organelle organization | 30.7143 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.0000 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 29.2857 | 6 | no |
| GO:0031399 | regulation of protein modification process | 29.2857 | 6 | no |
| GO:0023056 | positive regulation of signaling | 28.5714 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 27.8571 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 27.8571 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.8571 | 5 | no |
| GO:0008104 | protein localization | 27.1429 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 27.1429 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.1429 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.1429 | 6 | no |
| GO:0051049 | regulation of transport | 27.1429 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 26.4286 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 26.4286 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 26.4286 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 26.4286 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.4286 | 4 | no |
| GO:0036211 | protein modification process | 26.4286 | 4 | no |
| GO:0043412 | macromolecule modification | 26.4286 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 25.7143 | 5 | no |
| GO:0007010 | cytoskeleton organization | 25.0000 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 25.0000 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 25.0000 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 25.0000 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 24.2857 | 5 | no |
| GO:0043933 | protein-containing complex organization | 23.5714 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 23.5714 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.8571 | 6 | no |
| GO:0060341 | regulation of cellular localization | 22.8571 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 22.1429 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 22.1429 | 7 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.1429 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.1429 | 6 | no |
| GO:0032880 | regulation of protein localization | 22.1429 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 21.4286 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 20.7143 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 20.7143 | 8 | no |
| GO:0031401 | positive regulation of protein modification process | 20.7143 | 7 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.7143 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 20.7143 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 20.0000 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 18.5714 | 5 | yes |
| GO:0007015 | actin filament organization | 17.8571 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 17.8571 | 6 | yes |
| GO:0141124 | intracellular signaling cassette | 17.8571 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 17.8571 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 11.4286 | 7 | yes |
| GO:0022604 | regulation of cell morphogenesis | 10.0000 | 5 | yes |
| GO:0022411 | cellular component disassembly | 9.2857 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 9.2857 | 5 | yes |
| GO:0007264 | small GTPase-mediated signal transduction | 7.8571 | 5 | yes |
| GO:0032984 | protein-containing complex disassembly | 7.1429 | 5 | yes |
| GO:0008154 | actin polymerization or depolymerization | 5.7143 | 6 | yes |
| GO:0051261 | protein depolymerization | 5.0000 | 6 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 5.0000 | 4 | yes |
| GO:0000281 | mitotic cytokinesis | 4.2857 | 4 | yes |
| GO:0030042 | actin filament depolymerization | 4.2857 | 7 | yes |
| GO:0099175 | regulation of postsynapse organization | 4.2857 | 6 | yes |
| GO:0007266 | Rho protein signal transduction | 3.5714 | 6 | yes |
| GO:0030043 | actin filament fragmentation | 3.5714 | 8 | yes |
| GO:0044788 | modulation by host of viral process | 3.5714 | 5 | yes |
| GO:0051851 | modulation by host of symbiont process | 3.5714 | 4 | yes |
| GO:0045995 | regulation of embryonic development | 2.8571 | 5 | yes |
| GO:0051293 | establishment of spindle localization | 2.8571 | 4 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 2.8571 | 5 | yes |
| GO:0040019 | positive regulation of embryonic development | 2.1429 | 5 | yes |
| GO:0044794 | positive regulation by host of viral process | 2.1429 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FBX31_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| H2AX_HUMAN | [view interactions] | Low throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SSH2_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HUNK_HUMAN | [view interactions] | Low throughput | no | yes |
| IPO9_HUMAN | [view interactions] | Low throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| 1433G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLD1_HUMAN | [view interactions] | Low throughput | no | no |
| PLD2_HUMAN | [view interactions] | Low throughput | no | yes |
| SSH1_HUMAN | [view interactions] | Low throughput | no | yes |
| LIMK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TXD17_HUMAN | [view interactions] | Low throughput | no | yes |
| CAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTS_HUMAN | [view interactions] | Low throughput | no | no |
| ROCK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LIMK2_HUMAN | [view interactions] | Low throughput | no | yes |
| TPIS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UBC12_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF2B1_HUMAN | [view interactions] | Low throughput | no | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI31_HUMAN | [view interactions] | High throughput | no | no |
| FOLR1_HUMAN | [view interactions] | High throughput | no | no |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| TP8L1_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TAB1_HUMAN | [view interactions] | High throughput | no | yes |
| MBD5_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| MBD6_HUMAN | [view interactions] | High throughput | no | yes |
| JIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG10_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN2_HUMAN | [view interactions] | High throughput | no | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FND3B_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI15_HUMAN | [view interactions] | High throughput | no | no |
| SESD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GABT_HUMAN | [view interactions] | High throughput | no | yes |
| CAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AL4A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| CAPG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| CKS2_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| COTL1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CASP9_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| ALAT1_HUMAN | [view interactions] | High throughput | no | no |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| ALAT2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| KYNU_HUMAN | [view interactions] | High throughput | no | no |
| ZN724_HUMAN | [view interactions] | High throughput | no | no |
| NU214_HUMAN | [view interactions] | High throughput | no | no |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| PTGR1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DXO_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| RAIN_HUMAN | [view interactions] | High throughput | no | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| SSX1_HUMAN | [view interactions] | High throughput | no | no |
| SRXN1_HUMAN | [view interactions] | High throughput | no | no |
| T10IP_HUMAN | [view interactions] | High throughput | no | no |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3D_HUMAN | [view interactions] | High throughput | no | yes |
| COX17_HUMAN | [view interactions] | High throughput | no | yes |
| IRGM_HUMAN | [view interactions] | High throughput | no | no |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPH1_HUMAN | [view interactions] | High throughput | no | yes |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAHD1_HUMAN | [view interactions] | High throughput | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDHD1_HUMAN | [view interactions] | High throughput | no | yes |
| JUPI1_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LDH6A_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| LYPA2_HUMAN | [view interactions] | High throughput | no | no |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SATB2_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| TNG2_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFM1_HUMAN | [view interactions] | High throughput | no | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| KAD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCBP_HUMAN | [view interactions] | High throughput | no | yes |
| ISOC2_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACOT1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYCM_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| FAH2A_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| AL7A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POTE1_HUMAN | [view interactions] | High throughput | no | no |
| AATM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| R113A_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP45_HUMAN | [view interactions] | High throughput | no | yes |
| SNRPA_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| HNRH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| FBX25_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| STYX_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| DC4L2_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPRL2_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2L6_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| TISD_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCD15_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| VRK3_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| RHG31_HUMAN | [view interactions] | High throughput | no | yes |
| ARGAL_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGI_HUMAN | [view interactions] | High throughput | no | no |
| SYDE2_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAISO_HUMAN | [view interactions] | High throughput | no | yes |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTA_HUMAN | [view interactions] | High throughput | no | no |
| EMAL4_HUMAN | [view interactions] | High throughput | no | yes |