Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ACON_HUMAN

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ACON_HUMAN
GO:0003723 RNA binding 35.3741 4 no
GO:0046872 metal ion binding 27.2109 4 yes
GO:0046914 transition metal ion binding 4.0816 5 yes
GO:0016836 hydro-lyase activity 3.4014 4 yes
GO:0051539 4 iron, 4 sulfur cluster binding 2.7211 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ACON_HUMAN
GO:0060255 regulation of macromolecule metabolic process 34.6939 4 no
GO:0048522 positive regulation of cellular process 31.9728 4 no
GO:0080090 regulation of primary metabolic process 31.2925 4 no
GO:0031323 regulation of cellular metabolic process 30.6122 4 no
GO:0048523 negative regulation of cellular process 30.6122 4 no
GO:0051171 regulation of nitrogen compound metabolic process 30.6122 4 no
GO:0010468 regulation of gene expression 27.8912 5 no
GO:1901566 organonitrogen compound biosynthetic process 27.2109 4 no
GO:0043603 cellular amide metabolic process 26.5306 4 no
GO:0022607 cellular component assembly 26.5306 4 no
GO:0009893 positive regulation of metabolic process 25.8503 4 no
GO:0044271 cellular nitrogen compound biosynthetic process 25.8503 4 no
GO:0006796 phosphate-containing compound metabolic process 25.1701 4 no
GO:0019752 carboxylic acid metabolic process 23.8095 5 yes
GO:0043436 oxoacid metabolic process 23.8095 4 yes
GO:0010646 regulation of cell communication 23.8095 4 no
GO:0009966 regulation of signal transduction 22.4490 4 no
GO:0010604 positive regulation of macromolecule metabolic process 22.4490 5 no
GO:0043933 protein-containing complex organization 21.7687 4 no
GO:0043604 amide biosynthetic process 21.0884 5 no
GO:0009889 regulation of biosynthetic process 20.4082 4 no
GO:0010556 regulation of macromolecule biosynthetic process 20.4082 5 no
GO:1902652 secondary alcohol metabolic process 5.4422 4 yes
GO:0072350 tricarboxylic acid metabolic process 4.7619 6 yes
GO:0048732 gland development 4.0816 4 yes
GO:0006102 isocitrate metabolic process 3.4014 5 yes
GO:0001889 liver development 2.7211 5 yes
GO:0006101 citrate metabolic process 2.0408 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in ACON_HUMAN
DOID:331 central nervous system disease 2.0408 3 no
DOID:0050155 sensory system disease 1.3605 3 no
DOID:10584 retinitis pigmentosa 1.3605 7 no
DOID:5614 eye disease 1.3605 4 no
DOID:8466 retinal degeneration 1.3605 6 no
DOID:9799 eye degenerative disease 1.3605 5 no
DOID:1289 neurodegenerative disease 1.3605 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ITPR1_HUMAN [view entry] [view interactions] Low throughput yes yes
EMD_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
H31_HUMAN [view interactions] High throughput no yes
BUB3_HUMAN [view interactions] High throughput no yes
NFU1_HUMAN [view interactions] High throughput no yes
PUR8_HUMAN [view interactions] High throughput no yes
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
RUVB2_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TFE3_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
COMP_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
IDHP_HUMAN [view entry] [view interactions] High throughput yes yes
ERP44_HUMAN [view interactions] High throughput no yes
ACTN4_HUMAN [view entry] [view interactions] High throughput yes yes
GGH_HUMAN [view interactions] High throughput no yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
WDR5_HUMAN [view interactions] High throughput no no
THB_HUMAN [view interactions] High throughput no no
CLU_HUMAN [view interactions] High throughput no yes
LDLR_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
KAD3_HUMAN [view entry] [view interactions] High throughput yes yes
THIL_HUMAN [view entry] [view interactions] High throughput yes yes
SIN3A_HUMAN [view interactions] High throughput no yes
THIM_HUMAN [view interactions] High throughput no yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3G_HUMAN [view entry] [view interactions] High throughput yes yes
MYH7B_HUMAN [view interactions] High throughput no no
SODM_HUMAN [view entry] [view interactions] High throughput yes no
SSDH_HUMAN [view entry] [view interactions] High throughput yes yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
ALDOC_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
AT5F1_HUMAN [view interactions] High throughput no yes
ATP5J_HUMAN [view interactions] High throughput no yes
ESTD_HUMAN [view interactions] High throughput no yes
GPDA_HUMAN [view interactions] High throughput no yes
GPD1L_HUMAN [view interactions] High throughput no no
GPDM_HUMAN [view entry] [view interactions] High throughput yes yes
PIPNB_HUMAN [view interactions] High throughput no no
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
HINT2_HUMAN [view interactions] High throughput no yes
NENF_HUMAN [view interactions] High throughput no yes
KAD2_HUMAN [view interactions] High throughput no no
ACPM_HUMAN [view interactions] High throughput no yes
THTM_HUMAN [view interactions] High throughput no yes
GRHPR_HUMAN [view entry] [view interactions] High throughput yes no
THEM4_HUMAN [view interactions] High throughput no no
KCY_HUMAN [view entry] [view interactions] High throughput yes yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
PDIP2_HUMAN [view interactions] High throughput no no
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
NIT2_HUMAN [view interactions] High throughput no yes
HDHD3_HUMAN [view interactions] High throughput no yes
CLIC4_HUMAN [view interactions] High throughput no no
ETHE1_HUMAN [view interactions] High throughput no yes
GLRX5_HUMAN [view interactions] High throughput no yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no yes
ADPRS_HUMAN [view interactions] High throughput no yes
GLOD4_HUMAN [view entry] [view interactions] High throughput yes yes
PDP1_HUMAN [view interactions] High throughput no yes
AL4A1_HUMAN [view entry] [view interactions] High throughput yes yes
COPD_HUMAN [view entry] [view interactions] High throughput yes yes
CLIC1_HUMAN [view interactions] High throughput no no
COA7_HUMAN [view interactions] High throughput no yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
ADX_HUMAN [view interactions] High throughput no no
GCSH_HUMAN [view interactions] High throughput no yes
GSTO1_HUMAN [view entry] [view interactions] High throughput yes yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
6PGL_HUMAN [view interactions] High throughput no yes
PGM1_HUMAN [view interactions] High throughput no no
PRDX6_HUMAN [view entry] [view interactions] High throughput yes yes
SCP2_HUMAN [view interactions] High throughput no no
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5H_HUMAN [view interactions] High throughput no yes
LETM1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA3_HUMAN [view interactions] High throughput no yes
NDUA6_HUMAN [view interactions] High throughput no no
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV2_HUMAN [view entry] [view interactions] High throughput yes yes
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
ATPG_HUMAN [view interactions] High throughput no yes
ATP5I_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
COQ9_HUMAN [view interactions] High throughput no yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
NDUS2_HUMAN [view entry] [view interactions] High throughput yes yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
PFKAM_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
QCR9_HUMAN [view interactions] High throughput no no
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA5_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS4_HUMAN [view interactions] High throughput no yes
NDUS7_HUMAN [view entry] [view interactions] High throughput yes no
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
SDHB_HUMAN [view interactions] High throughput no yes
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
FUMH_HUMAN [view entry] [view interactions] High throughput yes yes
AATM_HUMAN [view entry] [view interactions] High throughput yes yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAC_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS6_HUMAN [view entry] [view interactions] High throughput yes yes
SDHF3_HUMAN [view interactions] High throughput no yes
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
ATPD_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
ATP5L_HUMAN [view interactions] High throughput no yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
MLH1_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
EFTS_HUMAN [view interactions] High throughput no no
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
SODC_HUMAN [view interactions] High throughput no yes
TCIM_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
TRI63_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
NEK7_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
CAV3_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
C5AR2_HUMAN [view interactions] High throughput no yes
KDM4C_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
CLPP_HUMAN [view interactions] High throughput no yes
PDK1_HUMAN [view interactions] High throughput no yes
ATX1L_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
PSMD4_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
ASB9_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
ABCG1_HUMAN [view interactions] High throughput no yes
P85A_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
RS27A_HUMAN [view entry] [view interactions] High throughput yes yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
TBB5_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
MYL6_HUMAN [view entry] [view interactions] High throughput yes no
IF6_HUMAN [view interactions] High throughput no yes
SPTB2_HUMAN [view entry] [view interactions] High throughput yes yes
OLA1_HUMAN [view entry] [view interactions] High throughput yes yes
PYR1_HUMAN [view entry] [view interactions] High throughput yes yes
OAT_HUMAN [view interactions] High throughput no yes
RS12_HUMAN [view entry] [view interactions] High throughput yes yes
HMCS1_HUMAN [view interactions] High throughput no yes
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
SYDC_HUMAN [view interactions] High throughput no yes
PRDX5_HUMAN [view entry] [view interactions] High throughput yes yes
GDIA_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
RS18_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
RL23A_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
RS15A_HUMAN [view entry] [view interactions] High throughput yes yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
SYEP_HUMAN [view interactions] High throughput no yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
RS5_HUMAN [view entry] [view interactions] High throughput yes yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
XPO2_HUMAN [view entry] [view interactions] High throughput yes no
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
RL12_HUMAN [view entry] [view interactions] High throughput yes yes
DHX15_HUMAN [view interactions] High throughput no yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
NHRF1_HUMAN [view interactions] High throughput no no
RS14_HUMAN [view entry] [view interactions] High throughput yes yes
API5_HUMAN [view interactions] High throughput no no
YAF2_HUMAN [view interactions] High throughput no yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
RACK1_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3I_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
RS13_HUMAN [view entry] [view interactions] High throughput yes yes
MIC19_HUMAN [view entry] [view interactions] High throughput yes yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
AR6P4_HUMAN [view interactions] High throughput no yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
XRCC6_HUMAN [view interactions] High throughput no yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
MPCP_HUMAN [view entry] [view interactions] High throughput yes no
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
LAP2A_HUMAN [view interactions] High throughput no yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
RHOQ_HUMAN [view interactions] High throughput no no
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
ACLY_HUMAN [view entry] [view interactions] Computational yes yes
TOM20_HUMAN [view entry] [view interactions] Computational yes yes
TOM5_HUMAN [view interactions] Computational no yes
IDH3B_HUMAN [view entry] [view interactions] Computational yes yes
CATA_HUMAN [view entry] [view interactions] Computational yes no
AT5G1_HUMAN [view interactions] Computational no no
TKT_HUMAN [view entry] [view interactions] Computational yes yes
ACOHC_HUMAN [view interactions] Computational no yes
PEPD_HUMAN [view interactions] Computational no yes
LONM_HUMAN [view entry] [view interactions] Computational yes yes
GABT_HUMAN [view interactions] Computational no yes
OGDHL_HUMAN [view entry] [view interactions] Computational yes yes
TALDO_HUMAN [view entry] [view interactions] Computational yes no
AGT2_HUMAN [view interactions] Computational no no
ATPB_HUMAN [view interactions] Computational no yes
BCS1_HUMAN [view interactions] Computational no yes
TOM40_HUMAN [view interactions] Computational no yes
MMSA_HUMAN [view entry] [view interactions] Computational yes no
ISCU_HUMAN [view interactions] Computational no yes
SPYA_HUMAN [view interactions] Computational no no
TOM70_HUMAN [view interactions] Computational no yes
TOM22_HUMAN [view interactions] Computational no yes
TOM7_HUMAN [view interactions] Computational no no
TIM22_HUMAN [view interactions] Computational no no
TOM6_HUMAN [view interactions] Computational no yes
ALAT2_HUMAN [view interactions] Computational no yes
IDHC_HUMAN [view interactions] Computational no no
3HIDH_HUMAN [view interactions] Computational no yes