M2OM_HUMAN
Evidence for PS localization
Functions
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed). Involved in the regulation of apoptosis . Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in M2OM_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 35.2273 | 4 | no |
| GO:0043169 | cation binding | 32.9545 | 4 | no |
| GO:0043168 | anion binding | 32.9545 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.6818 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.6818 | 4 | no |
| GO:0046872 | metal ion binding | 29.5455 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.4091 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 22.7273 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.7273 | 5 | no |
| GO:0005524 | ATP binding | 20.4545 | 5 | no |
| GO:0019900 | kinase binding | 20.4545 | 4 | no |
| GO:0003723 | RNA binding | 13.6364 | 4 | yes |
| GO:0015291 | secondary active transmembrane transporter activity | 4.5455 | 4 | yes |
| GO:0015297 | antiporter activity | 4.5455 | 5 | yes |
| GO:0015103 | inorganic anion transmembrane transporter activity | 3.4091 | 4 | yes |
| GO:0046943 | carboxylic acid transmembrane transporter activity | 3.4091 | 4 | yes |
| GO:0005310 | dicarboxylic acid transmembrane transporter activity | 2.2727 | 5 | yes |
| GO:0015116 | sulfate transmembrane transporter activity | 2.2727 | 4 | yes |
| GO:0015117 | thiosulfate transmembrane transporter activity | 2.2727 | 4 | yes |
| GO:0015131 | oxaloacetate transmembrane transporter activity | 2.2727 | 6 | yes |
| GO:0015139 | alpha-ketoglutarate transmembrane transporter activity | 2.2727 | 6 | yes |
| GO:0015140 | malate transmembrane transporter activity | 2.2727 | 6 | yes |
| GO:0015141 | succinate transmembrane transporter activity | 2.2727 | 6 | yes |
| GO:0015367 | oxoglutarate:malate antiporter activity | 2.2727 | 6 | yes |
| GO:0015556 | C4-dicarboxylate transmembrane transporter activity | 2.2727 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in M2OM_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 65.9091 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 54.5455 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 52.2727 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 51.1364 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 48.8636 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 44.3182 | 4 | no |
| GO:0006996 | organelle organization | 43.1818 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.0455 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 42.0455 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 40.9091 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.9091 | 5 | no |
| GO:0010468 | regulation of gene expression | 39.7727 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 39.7727 | 5 | no |
| GO:0022607 | cellular component assembly | 39.7727 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 39.7727 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 39.7727 | 5 | no |
| GO:0051049 | regulation of transport | 38.6364 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 38.6364 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 36.3636 | 5 | no |
| GO:0023056 | positive regulation of signaling | 36.3636 | 4 | no |
| GO:0008104 | protein localization | 35.2273 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 35.2273 | 5 | no |
| GO:0031399 | regulation of protein modification process | 35.2273 | 6 | no |
| GO:0033043 | regulation of organelle organization | 34.0909 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.9545 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.9545 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 32.9545 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 31.8182 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 31.8182 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 30.6818 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 30.6818 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.6818 | 5 | no |
| GO:0071702 | organic substance transport | 29.5455 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 29.5455 | 7 | no |
| GO:0042981 | regulation of apoptotic process | 29.5455 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 29.5455 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 28.4091 | 6 | no |
| GO:0060341 | regulation of cellular localization | 28.4091 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 28.4091 | 7 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 28.4091 | 4 | no |
| GO:0071310 | cellular response to organic substance | 27.2727 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 27.2727 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 27.2727 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.2727 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 27.2727 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 27.2727 | 6 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.1364 | 4 | no |
| GO:0009894 | regulation of catabolic process | 26.1364 | 4 | no |
| GO:0032880 | regulation of protein localization | 26.1364 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.1364 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 26.1364 | 4 | no |
| GO:0043933 | protein-containing complex organization | 26.1364 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.0000 | 6 | no |
| GO:0071705 | nitrogen compound transport | 25.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 23.8636 | 5 | no |
| GO:0051050 | positive regulation of transport | 23.8636 | 4 | no |
| GO:0080134 | regulation of response to stress | 23.8636 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.8636 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.8636 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 23.8636 | 7 | no |
| GO:0010243 | response to organonitrogen compound | 22.7273 | 4 | no |
| GO:0030030 | cell projection organization | 22.7273 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 22.7273 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.7273 | 6 | no |
| GO:0007010 | cytoskeleton organization | 22.7273 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.7273 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 22.7273 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.7273 | 4 | no |
| GO:0036211 | protein modification process | 22.7273 | 4 | no |
| GO:0043412 | macromolecule modification | 22.7273 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 22.7273 | 4 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.7273 | 7 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.5909 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 21.5909 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 21.5909 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.5909 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.5909 | 6 | no |
| GO:1903829 | positive regulation of protein localization | 21.5909 | 5 | no |
| GO:0042327 | positive regulation of phosphorylation | 21.5909 | 8 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.5909 | 5 | no |
| GO:0002684 | positive regulation of immune system process | 20.4545 | 4 | no |
| GO:0014070 | response to organic cyclic compound | 20.4545 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 20.4545 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 20.4545 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.4545 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 20.4545 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 20.4545 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 20.4545 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.4545 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.4545 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.4545 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 20.4545 | 5 | no |
| GO:0006006 | glucose metabolic process | 5.6818 | 5 | yes |
| GO:0015711 | organic anion transport | 5.6818 | 5 | yes |
| GO:0015849 | organic acid transport | 5.6818 | 5 | yes |
| GO:0019318 | hexose metabolic process | 5.6818 | 4 | yes |
| GO:0046942 | carboxylic acid transport | 5.6818 | 6 | yes |
| GO:0006835 | dicarboxylic acid transport | 4.5455 | 7 | yes |
| GO:1905039 | carboxylic acid transmembrane transport | 4.5455 | 4 | yes |
| GO:0006094 | gluconeogenesis | 3.4091 | 6 | yes |
| GO:0006869 | lipid transport | 3.4091 | 5 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 3.4091 | 4 | yes |
| GO:0019319 | hexose biosynthetic process | 3.4091 | 5 | yes |
| GO:0046364 | monosaccharide biosynthetic process | 3.4091 | 4 | yes |
| GO:0006817 | phosphate ion transport | 2.2727 | 5 | yes |
| GO:0008272 | sulfate transport | 2.2727 | 5 | yes |
| GO:0015698 | inorganic anion transport | 2.2727 | 4 | yes |
| GO:0015709 | thiosulfate transport | 2.2727 | 5 | yes |
| GO:0015729 | oxaloacetate transport | 2.2727 | 9 | yes |
| GO:0015740 | C4-dicarboxylate transport | 2.2727 | 8 | yes |
| GO:0015743 | malate transport | 2.2727 | 9 | yes |
| GO:0015744 | succinate transport | 2.2727 | 9 | yes |
| GO:0035435 | phosphate ion transmembrane transport | 2.2727 | 5 | yes |
| GO:0071422 | succinate transmembrane transport | 2.2727 | 5 | yes |
| GO:0071423 | malate transmembrane transport | 2.2727 | 5 | yes |
| GO:0072348 | sulfur compound transport | 2.2727 | 4 | yes |
| GO:0098661 | inorganic anion transmembrane transport | 2.2727 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| M2OM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SIM26_HUMAN | [view interactions] | Low throughput | no | no |
| AGK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RECQ1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| S22A1_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM65_HUMAN | [view interactions] | High throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| COA3_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| HEM6_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEMH_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPOX_HUMAN | [view interactions] | High throughput | no | no |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| POTEI_HUMAN | [view interactions] | High throughput | no | no |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| PRG2_HUMAN | [view interactions] | High throughput | no | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| PPR1A_HUMAN | [view interactions] | High throughput | no | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD1_HUMAN | [view interactions] | High throughput | no | no |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| ZN703_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHC10_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| BOLA3_HUMAN | [view interactions] | High throughput | no | yes |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| ELK1_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| GRHL1_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4A4A_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| ELF4_HUMAN | [view interactions] | High throughput | no | no |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UD2B7_HUMAN | [view interactions] | High throughput | no | no |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| C5AR2_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KKCC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| CLN5_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW4_HUMAN | [view interactions] | High throughput | no | no |
| FBX46_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| REN3B_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIPI4_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| AP4AT_HUMAN | [view interactions] | High throughput | no | no |
| KRBX4_HUMAN | [view interactions] | High throughput | no | no |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| TXTP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD9_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| KDF1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| MAGBA_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| KCNA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| GRAM4_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| IF2B3_HUMAN | [view interactions] | High throughput | no | no |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| R113A_HUMAN | [view interactions] | High throughput | no | yes |
| GATA4_HUMAN | [view interactions] | High throughput | no | no |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| FBX42_HUMAN | [view interactions] | High throughput | no | yes |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |