M2OM_HUMAN
Evidence for PS localization
Functions
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed). Involved in the regulation of apoptosis . Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in M2OM_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 27.2727 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 27.2727 | 4 | no |
| GO:0046872 | metal ion binding | 25.9740 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.6753 | 4 | no |
| GO:0019900 | kinase binding | 22.0779 | 4 | no |
| GO:0003723 | RNA binding | 10.3896 | 4 | yes |
| GO:0008509 | anion transmembrane transporter activity | 9.0909 | 4 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 9.0909 | 4 | yes |
| GO:0015103 | inorganic anion transmembrane transporter activity | 7.7922 | 4 | yes |
| GO:0015291 | secondary active transmembrane transporter activity | 5.1948 | 4 | yes |
| GO:0008514 | organic anion transmembrane transporter activity | 3.8961 | 5 | yes |
| GO:0046943 | carboxylic acid transmembrane transporter activity | 3.8961 | 4 | yes |
| GO:0005310 | dicarboxylic acid transmembrane transporter activity | 2.5974 | 5 | yes |
| GO:0015116 | sulfate transmembrane transporter activity | 2.5974 | 4 | yes |
| GO:0015117 | thiosulfate transmembrane transporter activity | 2.5974 | 4 | yes |
| GO:0015131 | oxaloacetate transmembrane transporter activity | 2.5974 | 6 | yes |
| GO:0015139 | alpha-ketoglutarate transmembrane transporter activity | 2.5974 | 6 | yes |
| GO:0015140 | malate transmembrane transporter activity | 2.5974 | 6 | yes |
| GO:0015141 | succinate transmembrane transporter activity | 2.5974 | 6 | yes |
| GO:0015297 | antiporter activity | 2.5974 | 5 | yes |
| GO:0015367 | oxoglutarate:malate antiporter activity | 2.5974 | 5 | yes |
| GO:0015556 | C4-dicarboxylate transmembrane transporter activity | 2.5974 | 6 | yes |
| GO:0140323 | solute:anion antiporter activity | 2.5974 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in M2OM_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.0390 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 53.2468 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.6494 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.0519 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 46.7532 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.7532 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 44.1558 | 4 | no |
| GO:0010646 | regulation of cell communication | 44.1558 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 41.5584 | 4 | no |
| GO:0006996 | organelle organization | 41.5584 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 40.2597 | 5 | no |
| GO:0022607 | cellular component assembly | 38.9610 | 4 | no |
| GO:0009966 | regulation of signal transduction | 38.9610 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.9610 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.9610 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 36.3636 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 36.3636 | 5 | no |
| GO:0051049 | regulation of transport | 36.3636 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 36.3636 | 6 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.0649 | 5 | no |
| GO:0010468 | regulation of gene expression | 35.0649 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.7662 | 4 | no |
| GO:0031399 | regulation of protein modification process | 33.7662 | 6 | no |
| GO:0036211 | protein modification process | 32.4675 | 4 | no |
| GO:0043412 | macromolecule modification | 32.4675 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.4675 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.1688 | 5 | no |
| GO:0033043 | regulation of organelle organization | 31.1688 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 31.1688 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 31.1688 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.1688 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 31.1688 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 29.8701 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 29.8701 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.5714 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 28.5714 | 5 | no |
| GO:0071310 | cellular response to organic substance | 28.5714 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 28.5714 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.5714 | 5 | no |
| GO:0010941 | regulation of cell death | 28.5714 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 25.9740 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 25.9740 | 7 | no |
| GO:0051338 | regulation of transferase activity | 25.9740 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 25.9740 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.9740 | 6 | no |
| GO:0030030 | cell projection organization | 25.9740 | 4 | no |
| GO:0051050 | positive regulation of transport | 25.9740 | 4 | no |
| GO:0008104 | protein localization | 25.9740 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.9740 | 6 | no |
| GO:0009894 | regulation of catabolic process | 25.9740 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.9740 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 25.9740 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 24.6753 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 24.6753 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 24.6753 | 4 | no |
| GO:0043549 | regulation of kinase activity | 24.6753 | 5 | no |
| GO:0060341 | regulation of cellular localization | 24.6753 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 24.6753 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 24.6753 | 4 | no |
| GO:0071702 | organic substance transport | 24.6753 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 24.6753 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.6753 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 23.3766 | 7 | no |
| GO:0042127 | regulation of cell population proliferation | 23.3766 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.3766 | 6 | no |
| GO:0007010 | cytoskeleton organization | 23.3766 | 5 | no |
| GO:0010638 | positive regulation of organelle organization | 23.3766 | 6 | no |
| GO:0032880 | regulation of protein localization | 23.3766 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.3766 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.0779 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.0779 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.0779 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.0779 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.7792 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.7792 | 5 | no |
| GO:0031329 | regulation of cellular catabolic process | 20.7792 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 20.7792 | 5 | no |
| GO:0080134 | regulation of response to stress | 20.7792 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.7792 | 6 | no |
| GO:1903829 | positive regulation of protein localization | 20.7792 | 5 | no |
| GO:0043933 | protein-containing complex organization | 20.7792 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.7792 | 6 | no |
| GO:0006811 | ion transport | 16.8831 | 4 | yes |
| GO:0006820 | anion transport | 7.7922 | 5 | yes |
| GO:0098660 | inorganic ion transmembrane transport | 6.4935 | 4 | yes |
| GO:0015711 | organic anion transport | 5.1948 | 5 | yes |
| GO:0015849 | organic acid transport | 5.1948 | 5 | yes |
| GO:0046942 | carboxylic acid transport | 5.1948 | 6 | yes |
| GO:0098656 | anion transmembrane transport | 5.1948 | 4 | yes |
| GO:1905039 | carboxylic acid transmembrane transport | 5.1948 | 4 | yes |
| GO:0006835 | dicarboxylic acid transport | 3.8961 | 7 | yes |
| GO:0006817 | phosphate ion transport | 2.5974 | 7 | yes |
| GO:0008272 | sulfate transport | 2.5974 | 5 | yes |
| GO:0015698 | inorganic anion transport | 2.5974 | 6 | yes |
| GO:0015709 | thiosulfate transport | 2.5974 | 5 | yes |
| GO:0015729 | oxaloacetate transport | 2.5974 | 6 | yes |
| GO:0015740 | C4-dicarboxylate transport | 2.5974 | 8 | yes |
| GO:0015743 | malate transport | 2.5974 | 6 | yes |
| GO:0015744 | succinate transport | 2.5974 | 6 | yes |
| GO:0035435 | phosphate ion transmembrane transport | 2.5974 | 6 | yes |
| GO:0071422 | succinate transmembrane transport | 2.5974 | 5 | yes |
| GO:0071423 | malate transmembrane transport | 2.5974 | 5 | yes |
| GO:0072348 | sulfur compound transport | 2.5974 | 4 | yes |
| GO:0098661 | inorganic anion transmembrane transport | 2.5974 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in M2OM_HUMAN |
|---|---|---|---|---|
| DOID:0050890 | synucleinopathy | 2.5974 | 5 | no |
| DOID:0060892 | late onset Parkinsons disease | 2.5974 | 7 | no |
| DOID:1289 | neurodegenerative disease | 2.5974 | 4 | no |
| DOID:14330 | Parkinsons disease | 2.5974 | 6 | no |
| DOID:331 | central nervous system disease | 2.5974 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| M2OM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD9_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| KDF1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| MAGBA_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| KCNA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| GRAM4_HUMAN | [view interactions] | High throughput | no | no |
| S22A1_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM65_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| COA3_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| HEM6_HUMAN | [view interactions] | High throughput | no | no |
| HEMH_HUMAN | [view interactions] | High throughput | no | yes |
| PPOX_HUMAN | [view interactions] | High throughput | no | no |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN703_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD1_HUMAN | [view interactions] | High throughput | no | no |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| PPR1A_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRG2_HUMAN | [view interactions] | High throughput | no | no |
| POTEI_HUMAN | [view interactions] | High throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| CHC10_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH2_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| BOLA3_HUMAN | [view interactions] | High throughput | no | yes |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| ELK1_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view interactions] | High throughput | no | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4A4A_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| ELF4_HUMAN | [view interactions] | High throughput | no | no |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALR_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| C5AR2_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KKCC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| CLN5_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW4_HUMAN | [view interactions] | High throughput | no | no |
| FBX46_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| REN3B_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIPI4_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| AP4AT_HUMAN | [view interactions] | High throughput | no | no |
| KRBX4_HUMAN | [view interactions] | High throughput | no | no |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| TXTP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |