YES_HUMAN
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI000133 | MOD_TYR_CSK | MOD | 533 | 541 | - |
ELMI000133 | MOD_TYR_CSK | MOD | 533 | 541 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in YES_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 41.3534 | 4 | yes |
GO:0000166 | nucleotide binding | 39.0977 | 4 | yes |
GO:0017076 | purine nucleotide binding | 39.0977 | 5 | yes |
GO:0032555 | purine ribonucleotide binding | 39.0977 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 39.0977 | 4 | yes |
GO:0019900 | kinase binding | 30.0752 | 4 | no |
GO:0019901 | protein kinase binding | 27.8195 | 5 | no |
GO:0005524 | ATP binding | 26.3158 | 5 | yes |
GO:0030554 | adenyl nucleotide binding | 26.3158 | 6 | yes |
GO:0032559 | adenyl ribonucleotide binding | 26.3158 | 5 | yes |
GO:0043169 | cation binding | 25.5639 | 4 | no |
GO:0046872 | metal ion binding | 25.5639 | 5 | no |
GO:0016462 | pyrophosphatase activity | 21.8045 | 5 | no |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 21.8045 | 4 | no |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 21.0526 | 6 | no |
GO:0016301 | kinase activity | 15.0376 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 15.0376 | 4 | yes |
GO:0004713 | protein tyrosine kinase activity | 11.2782 | 4 | yes |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 7.5188 | 5 | yes |
GO:0045309 | protein phosphorylated amino acid binding | 6.7669 | 4 | yes |
GO:0001784 | phosphotyrosine residue binding | 6.0150 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in YES_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 72.9323 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 61.6541 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 60.9023 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 54.1353 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 53.3835 | 4 | no |
GO:0051128 | regulation of cellular component organization | 53.3835 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 51.8797 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 50.3759 | 5 | yes |
GO:0010646 | regulation of cell communication | 47.3684 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 47.3684 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 47.3684 | 5 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 47.3684 | 5 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 46.6165 | 5 | yes |
GO:0022607 | cellular component assembly | 45.1128 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 44.3609 | 5 | yes |
GO:0010468 | regulation of gene expression | 42.8571 | 6 | yes |
GO:0051049 | regulation of transport | 40.6015 | 4 | yes |
GO:0008104 | protein localization | 40.6015 | 4 | no |
GO:0009966 | regulation of signal transduction | 40.6015 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 39.8496 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 38.3459 | 6 | yes |
GO:0006996 | organelle organization | 38.3459 | 4 | no |
GO:0031399 | regulation of protein modification process | 34.5865 | 6 | yes |
GO:0010647 | positive regulation of cell communication | 33.8346 | 5 | no |
GO:0023056 | positive regulation of signaling | 33.8346 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 33.0827 | 5 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 33.0827 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 32.3308 | 5 | yes |
GO:0060341 | regulation of cellular localization | 32.3308 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 32.3308 | 6 | yes |
GO:0044087 | regulation of cellular component biogenesis | 31.5789 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 31.5789 | 6 | yes |
GO:0042325 | regulation of phosphorylation | 30.8271 | 7 | yes |
GO:0032880 | regulation of protein localization | 30.8271 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 30.8271 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 30.8271 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 30.8271 | 7 | yes |
GO:0009892 | negative regulation of metabolic process | 30.0752 | 4 | no |
GO:0033043 | regulation of organelle organization | 29.3233 | 5 | no |
GO:0051130 | positive regulation of cellular component organization | 29.3233 | 5 | no |
GO:0071702 | organic substance transport | 29.3233 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 29.3233 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.3233 | 5 | yes |
GO:0031401 | positive regulation of protein modification process | 29.3233 | 7 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 28.5714 | 5 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 27.8195 | 7 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 27.8195 | 4 | yes |
GO:0030030 | cell projection organization | 27.8195 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 27.8195 | 6 | yes |
GO:0042327 | positive regulation of phosphorylation | 27.0677 | 8 | yes |
GO:0071705 | nitrogen compound transport | 27.0677 | 4 | no |
GO:0043067 | regulation of programmed cell death | 27.0677 | 4 | no |
GO:0001934 | positive regulation of protein phosphorylation | 27.0677 | 8 | yes |
GO:0042981 | regulation of apoptotic process | 25.5639 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 25.5639 | 5 | no |
GO:0042127 | regulation of cell population proliferation | 24.8120 | 4 | no |
GO:0030334 | regulation of cell migration | 24.0602 | 5 | no |
GO:2000145 | regulation of cell motility | 24.0602 | 4 | no |
GO:0043085 | positive regulation of catalytic activity | 24.0602 | 4 | no |
GO:0030155 | regulation of cell adhesion | 24.0602 | 4 | yes |
GO:0036211 | protein modification process | 23.3083 | 4 | yes |
GO:0043412 | macromolecule modification | 23.3083 | 4 | yes |
GO:0051252 | regulation of RNA metabolic process | 23.3083 | 5 | yes |
GO:0071310 | cellular response to organic substance | 23.3083 | 4 | yes |
GO:0043933 | protein-containing complex organization | 23.3083 | 4 | no |
GO:0031344 | regulation of cell projection organization | 23.3083 | 5 | no |
GO:0002684 | positive regulation of immune system process | 23.3083 | 4 | yes |
GO:0015031 | protein transport | 22.5564 | 4 | no |
GO:0010628 | positive regulation of gene expression | 22.5564 | 7 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 22.5564 | 6 | no |
GO:0009890 | negative regulation of biosynthetic process | 22.5564 | 5 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.5564 | 6 | no |
GO:0032101 | regulation of response to external stimulus | 22.5564 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.8045 | 4 | no |
GO:0051094 | positive regulation of developmental process | 21.8045 | 4 | no |
GO:1903829 | positive regulation of protein localization | 21.8045 | 5 | no |
GO:0051050 | positive regulation of transport | 21.8045 | 4 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.8045 | 6 | no |
GO:0031327 | negative regulation of cellular biosynthetic process | 21.8045 | 6 | no |
GO:0006796 | phosphate-containing compound metabolic process | 21.8045 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 21.0526 | 4 | no |
GO:2001141 | regulation of RNA biosynthetic process | 20.3008 | 6 | yes |
GO:0065003 | protein-containing complex assembly | 20.3008 | 5 | no |
GO:2000026 | regulation of multicellular organismal development | 20.3008 | 4 | no |
GO:0051493 | regulation of cytoskeleton organization | 20.3008 | 6 | no |
GO:0060627 | regulation of vesicle-mediated transport | 20.3008 | 4 | no |
GO:0051338 | regulation of transferase activity | 20.3008 | 4 | no |
GO:0061024 | membrane organization | 20.3008 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 20.3008 | 7 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 19.5489 | 5 | yes |
GO:0050776 | regulation of immune response | 19.5489 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 18.7970 | 4 | yes |
GO:0080134 | regulation of response to stress | 18.7970 | 4 | yes |
GO:0050778 | positive regulation of immune response | 17.2932 | 5 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 17.2932 | 4 | yes |
GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 17.2932 | 5 | yes |
GO:0045785 | positive regulation of cell adhesion | 15.7895 | 5 | yes |
GO:0031347 | regulation of defense response | 15.7895 | 5 | yes |
GO:0016310 | phosphorylation | 15.0376 | 5 | yes |
GO:0022407 | regulation of cell-cell adhesion | 14.2857 | 5 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 13.5338 | 6 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 13.5338 | 4 | yes |
GO:0050865 | regulation of cell activation | 12.7820 | 4 | yes |
GO:0002694 | regulation of leukocyte activation | 12.7820 | 4 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 12.7820 | 8 | yes |
GO:0051249 | regulation of lymphocyte activation | 12.0301 | 5 | yes |
GO:0071363 | cellular response to growth factor stimulus | 12.0301 | 4 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 11.2782 | 8 | yes |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 11.2782 | 8 | yes |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 11.2782 | 9 | yes |
GO:0050863 | regulation of T cell activation | 11.2782 | 6 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 11.2782 | 7 | yes |
GO:0033993 | response to lipid | 10.5263 | 4 | yes |
GO:0034762 | regulation of transmembrane transport | 10.5263 | 4 | yes |
GO:0022409 | positive regulation of cell-cell adhesion | 10.5263 | 6 | yes |
GO:0140546 | defense response to symbiont | 9.7744 | 4 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 9.7744 | 6 | yes |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 9.7744 | 4 | yes |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 9.7744 | 4 | yes |
GO:0050867 | positive regulation of cell activation | 9.0226 | 5 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 9.0226 | 6 | yes |
GO:0071396 | cellular response to lipid | 9.0226 | 5 | yes |
GO:0002683 | negative regulation of immune system process | 9.0226 | 4 | yes |
GO:0002696 | positive regulation of leukocyte activation | 9.0226 | 5 | yes |
GO:0050870 | positive regulation of T cell activation | 8.2707 | 7 | yes |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 8.2707 | 7 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 7.5188 | 9 | yes |
GO:0050727 | regulation of inflammatory response | 7.5188 | 5 | yes |
GO:0038093 | Fc receptor signaling pathway | 6.7669 | 5 | yes |
GO:0032102 | negative regulation of response to external stimulus | 6.7669 | 5 | yes |
GO:0038094 | Fc-gamma receptor signaling pathway | 6.0150 | 6 | yes |
GO:0048013 | ephrin receptor signaling pathway | 6.0150 | 6 | yes |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.2632 | 4 | yes |
GO:0050728 | negative regulation of inflammatory response | 5.2632 | 6 | yes |
GO:0002431 | Fc receptor mediated stimulatory signaling pathway | 5.2632 | 5 | yes |
GO:0031348 | negative regulation of defense response | 5.2632 | 5 | yes |
GO:0050777 | negative regulation of immune response | 4.5113 | 5 | yes |
GO:0002861 | regulation of inflammatory response to antigenic stimulus | 4.5113 | 5 | yes |
GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 4.5113 | 6 | yes |
GO:0003018 | vascular process in circulatory system | 4.5113 | 4 | yes |
GO:0071559 | response to transforming growth factor beta | 3.7594 | 4 | yes |
GO:0071560 | cellular response to transforming growth factor beta stimulus | 3.7594 | 5 | yes |
GO:0032526 | response to retinoic acid | 3.0075 | 4 | yes |
GO:0036119 | response to platelet-derived growth factor | 3.0075 | 4 | yes |
GO:0036120 | cellular response to platelet-derived growth factor stimulus | 3.0075 | 5 | yes |
GO:0071300 | cellular response to retinoic acid | 3.0075 | 5 | yes |
GO:0010827 | regulation of glucose transmembrane transport | 2.2556 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NPHN_HUMAN | [view interactions] | Low throughput | no | no |
CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
OCLN_HUMAN | [view interactions] | Low throughput | no | no |
RASA1_HUMAN | [view interactions] | Low throughput | no | yes |
CD36_HUMAN | [view interactions] | Low throughput | no | no |
PECA1_HUMAN | [view interactions] | Low throughput | no | no |
TRPV4_HUMAN | [view interactions] | Low throughput | no | yes |
MCP_HUMAN | [view interactions] | Low throughput | no | no |
DIAP1_HUMAN | [view interactions] | Low throughput | no | yes |
EDNRA_HUMAN | [view interactions] | Low throughput | no | yes |
DAB1_HUMAN | [view interactions] | Low throughput | no | yes |
ACSL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P85A_HUMAN | [view interactions] | Low throughput | no | yes |
IL1R1_HUMAN | [view interactions] | Low throughput | no | no |
GPVI_HUMAN | [view interactions] | Low throughput | no | no |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
ACK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SOCS1_HUMAN | [view interactions] | Low throughput | no | yes |
MED28_HUMAN | [view interactions] | Low throughput | no | yes |
ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PTPRE_HUMAN | [view interactions] | Low throughput | no | no |
FLOT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSF1R_HUMAN | [view interactions] | Low throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
RL10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
FGFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
EPHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
OGT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TNR6_HUMAN | [view interactions] | Low throughput | no | no |
NCOA2_HUMAN | [view interactions] | Low throughput | no | no |
CDCP1_HUMAN | [view interactions] | Low throughput | no | yes |
YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
VGFR1_HUMAN | [view interactions] | Low throughput | no | no |
CDN1B_HUMAN | [view interactions] | Low throughput | no | yes |
LOX5_HUMAN | [view interactions] | Low throughput | no | no |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SPR2A_HUMAN | [view interactions] | Low throughput | no | no |
KHDR1_HUMAN | [view interactions] | Low throughput | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRIM5_HUMAN | [view interactions] | High throughput | no | yes |
CCD33_HUMAN | [view interactions] | High throughput | no | no |
FACC1_HUMAN | [view interactions] | High throughput | no | no |
CEP83_HUMAN | [view interactions] | High throughput | no | yes |
DEN2C_HUMAN | [view interactions] | High throughput | no | no |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
CARD9_HUMAN | [view interactions] | High throughput | no | no |
TRI69_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAN2_HUMAN | [view interactions] | High throughput | no | no |
CUL7_HUMAN | [view interactions] | High throughput | no | yes |
GPR35_HUMAN | [view interactions] | High throughput | no | no |
GRPE2_HUMAN | [view interactions] | High throughput | no | yes |
LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UIF_HUMAN | [view interactions] | High throughput | no | yes |
IKBA_HUMAN | [view interactions] | High throughput | no | yes |
ANR12_HUMAN | [view interactions] | High throughput | no | yes |
ZNT4_HUMAN | [view interactions] | High throughput | no | no |
JSPR1_HUMAN | [view interactions] | High throughput | no | no |
MOT14_HUMAN | [view interactions] | High throughput | no | yes |
CP51A_HUMAN | [view interactions] | High throughput | no | no |
CMAP3_HUMAN | [view interactions] | High throughput | no | no |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
BMR1A_HUMAN | [view interactions] | High throughput | no | no |
CALL3_HUMAN | [view interactions] | High throughput | no | yes |
RAD18_HUMAN | [view interactions] | High throughput | no | yes |
CP2S1_HUMAN | [view interactions] | High throughput | no | no |
DUS22_HUMAN | [view interactions] | High throughput | no | yes |
NICA_HUMAN | [view interactions] | High throughput | no | yes |
G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
CDK9_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
LARP7_HUMAN | [view interactions] | High throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNFL6_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IRS4_HUMAN | [view interactions] | High throughput | no | no |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASAP2_HUMAN | [view interactions] | High throughput | no | yes |
YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
DEN2B_HUMAN | [view interactions] | High throughput | no | yes |
KIF23_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAMD1_HUMAN | [view interactions] | High throughput | no | no |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
PEAR1_HUMAN | [view interactions] | High throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYPN_HUMAN | [view interactions] | High throughput | no | no |
SHIP1_HUMAN | [view interactions] | High throughput | no | no |
FA20C_HUMAN | [view interactions] | High throughput | no | no |
RBM33_HUMAN | [view interactions] | High throughput | no | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
DMRTB_HUMAN | [view interactions] | High throughput | no | no |
MALL_HUMAN | [view interactions] | High throughput | no | no |
SAM11_HUMAN | [view interactions] | High throughput | no | no |
CENPM_HUMAN | [view interactions] | High throughput | no | yes |
RBM15_HUMAN | [view interactions] | High throughput | no | yes |
RF1M_HUMAN | [view interactions] | High throughput | no | yes |
TEN1_HUMAN | [view interactions] | High throughput | no | no |
FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IFT52_HUMAN | [view interactions] | High throughput | no | no |
FA13A_HUMAN | [view interactions] | High throughput | no | yes |
ZPBP2_HUMAN | [view interactions] | High throughput | no | no |
Z512B_HUMAN | [view interactions] | High throughput | no | yes |
CEP15_HUMAN | [view interactions] | High throughput | no | yes |
DVL2_HUMAN | [view interactions] | High throughput | no | yes |
CENPK_HUMAN | [view interactions] | High throughput | no | no |
UT1_HUMAN | [view interactions] | High throughput | no | no |
OPALI_HUMAN | [view interactions] | High throughput | no | yes |
PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDR36_HUMAN | [view interactions] | High throughput | no | no |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FFAR1_HUMAN | [view interactions] | High throughput | no | no |
FLNB_HUMAN | [view interactions] | High throughput | no | no |
CEP43_HUMAN | [view interactions] | High throughput | no | no |
LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZDH23_HUMAN | [view interactions] | High throughput | no | no |
SIDT2_HUMAN | [view interactions] | High throughput | no | yes |
STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCDB3_HUMAN | [view interactions] | High throughput | no | no |
SODC_HUMAN | [view interactions] | High throughput | no | yes |
CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KSR1_HUMAN | [view interactions] | High throughput | no | yes |
XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MED21_HUMAN | [view interactions] | High throughput | no | yes |
ZCHC9_HUMAN | [view interactions] | High throughput | no | yes |
HXB5_HUMAN | [view interactions] | High throughput | no | no |
TMM59_HUMAN | [view interactions] | High throughput | no | yes |
CXB7_HUMAN | [view interactions] | High throughput | no | no |
CDK20_HUMAN | [view interactions] | High throughput | no | yes |
S2541_HUMAN | [view interactions] | High throughput | no | no |
PAL4C_HUMAN | [view interactions] | High throughput | no | no |
AIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAL4G_HUMAN | [view interactions] | High throughput | no | no |
PAI2_HUMAN | [view interactions] | High throughput | no | no |
SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FGR_HUMAN | [view interactions] | High throughput | no | no |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
ZFY27_HUMAN | [view interactions] | High throughput | no | yes |
H90B4_HUMAN | [view interactions] | High throughput | no | no |
PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H90B3_HUMAN | [view interactions] | High throughput | no | no |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
HS905_HUMAN | [view interactions] | High throughput | no | no |
GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS904_HUMAN | [view interactions] | High throughput | no | no |
RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
CC186_HUMAN | [view interactions] | High throughput | no | yes |
ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TGFR2_HUMAN | [view interactions] | High throughput | no | no |
CCNL2_HUMAN | [view interactions] | High throughput | no | yes |
NAT10_HUMAN | [view interactions] | High throughput | no | yes |
T185A_HUMAN | [view interactions] | High throughput | no | no |
BLMH_HUMAN | [view interactions] | High throughput | no | yes |
C1QL4_HUMAN | [view interactions] | High throughput | no | no |
SNG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCDGK_HUMAN | [view interactions] | High throughput | no | yes |
KC1G2_HUMAN | [view interactions] | High throughput | no | yes |
PRUN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VA0D2_HUMAN | [view interactions] | High throughput | no | no |
ACBD7_HUMAN | [view interactions] | High throughput | no | no |
TBD_HUMAN | [view interactions] | High throughput | no | yes |
CCR1_HUMAN | [view interactions] | High throughput | no | no |
NPC2_HUMAN | [view interactions] | High throughput | no | yes |
M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PIGM_HUMAN | [view interactions] | High throughput | no | no |
OCRL_HUMAN | [view interactions] | High throughput | no | yes |
FRIH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLRT1_HUMAN | [view interactions] | High throughput | no | no |
TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERLEC_HUMAN | [view interactions] | High throughput | no | yes |
RSMN_HUMAN | [view interactions] | High throughput | no | yes |
LTOR2_HUMAN | [view interactions] | High throughput | no | yes |
RSMB_HUMAN | [view interactions] | High throughput | no | yes |
KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPIN1_HUMAN | [view interactions] | High throughput | no | no |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
KPCD1_HUMAN | [view interactions] | High throughput | no | yes |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
IFM1_HUMAN | [view interactions] | High throughput | no | no |
SPF45_HUMAN | [view interactions] | High throughput | no | yes |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
CHERP_HUMAN | [view interactions] | High throughput | no | no |
SIK2_HUMAN | [view interactions] | High throughput | no | yes |
SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SF3B3_HUMAN | [view interactions] | High throughput | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SF3B2_HUMAN | [view interactions] | High throughput | no | yes |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERH_HUMAN | [view interactions] | High throughput | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
HNRC1_HUMAN | [view interactions] | High throughput | no | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CDK1_HUMAN | [view interactions] | High throughput | no | no |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
SF3B1_HUMAN | [view interactions] | High throughput | no | yes |
RHOD_HUMAN | [view interactions] | High throughput | no | no |
DHX15_HUMAN | [view interactions] | High throughput | no | yes |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
SR140_HUMAN | [view interactions] | High throughput | no | yes |
RHOU_HUMAN | [view interactions] | High throughput | no | no |
ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
NF2L2_HUMAN | [view interactions] | High throughput | no | yes |
RND1_HUMAN | [view interactions] | High throughput | no | no |
RND3_HUMAN | [view interactions] | High throughput | no | no |
VCAM1_HUMAN | [view interactions] | High throughput | no | no |
RHOV_HUMAN | [view interactions] | High throughput | no | no |
FINC_HUMAN | [view interactions] | High throughput | no | yes |
RND2_HUMAN | [view interactions] | High throughput | no | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
SOX2_HUMAN | [view interactions] | High throughput | no | yes |
RCBT2_HUMAN | [view interactions] | High throughput | no | yes |
STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYCN_HUMAN | [view interactions] | High throughput | no | no |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
DDR1_HUMAN | [view interactions] | High throughput | no | yes |
CLD4_HUMAN | [view interactions] | High throughput | no | yes |
RB27A_HUMAN | [view interactions] | High throughput | no | yes |
GBRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
EHD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KMT2A_HUMAN | [view interactions] | High throughput | no | yes |
PGM1_HUMAN | [view interactions] | High throughput | no | no |
ANR54_HUMAN | [view interactions] | High throughput | no | yes |
PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TUTLB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MSI2H_HUMAN | [view interactions] | High throughput | no | yes |
ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
PEX2_HUMAN | [view interactions] | High throughput | no | yes |
ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RPA1_HUMAN | [view interactions] | High throughput | no | yes |
GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLT3_HUMAN | [view interactions] | High throughput | no | no |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGFRA_HUMAN | [view interactions] | High throughput | no | no |
CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
LTOR3_HUMAN | [view interactions] | High throughput | no | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
SNX9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
SPRE_HUMAN | [view interactions] | High throughput | no | yes |
SHC2_HUMAN | [view interactions] | High throughput | no | yes |
MIDN_HUMAN | [view interactions] | High throughput | no | no |
SHF_HUMAN | [view interactions] | High throughput | no | no |
HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
SLAP1_HUMAN | [view interactions] | High throughput | no | yes |
DOK1_HUMAN | [view interactions] | High throughput | no | yes |
SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STAP2_HUMAN | [view interactions] | High throughput | no | yes |
NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TENS3_HUMAN | [view interactions] | High throughput | no | no |
PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TXK_HUMAN | [view interactions] | High throughput | no | no |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MBP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SKAP2_HUMAN | [view interactions] | High throughput | no | no |
LEG7_HUMAN | [view interactions] | High throughput | no | no |
DYLT1_HUMAN | [view interactions] | High throughput | no | no |
SPB4_HUMAN | [view interactions] | High throughput | no | no |
SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FAF2_HUMAN | [view interactions] | High throughput | no | yes |
DSC3_HUMAN | [view interactions] | High throughput | no | no |
TSR1_HUMAN | [view interactions] | High throughput | no | no |
ECM1_HUMAN | [view interactions] | High throughput | no | no |
ILF2_HUMAN | [view interactions] | High throughput | no | yes |
SYT6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
VATE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
POF1B_HUMAN | [view interactions] | High throughput | no | no |
NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGM1_HUMAN | [view interactions] | High throughput | no | no |
PIM3_HUMAN | [view interactions] | High throughput | no | no |
GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HASP_HUMAN | [view interactions] | High throughput | no | yes |
STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
OLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADA15_HUMAN | [view interactions] | High throughput | no | yes |
ERAP1_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
CK052_HUMAN | [view interactions] | High throughput | no | no |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
CXAR_HUMAN | [view interactions] | High throughput | no | yes |
DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
OLIG1_HUMAN | [view interactions] | High throughput | no | no |
EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BECN1_HUMAN | [view interactions] | High throughput | no | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOCS3_HUMAN | [view interactions] | High throughput | no | yes |
CXD3_HUMAN | [view interactions] | High throughput | no | no |
FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
LAMP3_HUMAN | [view interactions] | High throughput | no | no |
CA094_HUMAN | [view interactions] | High throughput | no | no |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FUND1_HUMAN | [view interactions] | High throughput | no | yes |
LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT8A_HUMAN | [view interactions] | High throughput | no | yes |
MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SSBP3_HUMAN | [view interactions] | High throughput | no | no |
AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THAP1_HUMAN | [view interactions] | High throughput | no | no |
RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRTP1_HUMAN | [view interactions] | High throughput | no | yes |
RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IKZF3_HUMAN | [view interactions] | High throughput | no | no |
RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STX6_HUMAN | [view interactions] | High throughput | no | yes |
BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AMOL2_HUMAN | [view interactions] | High throughput | no | no |
ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
CBLB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DPP4_HUMAN | [view interactions] | High throughput | no | no |
DESM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CHM1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
SOCS7_HUMAN | [view interactions] | High throughput | no | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SLN11_HUMAN | [view interactions] | High throughput | no | yes |
T10IP_HUMAN | [view interactions] | High throughput | no | no |
DTX2_HUMAN | [view interactions] | High throughput | no | yes |
DRC4_HUMAN | [view interactions] | High throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DDT4L_HUMAN | [view interactions] | High throughput | no | no |
RAB25_HUMAN | [view interactions] | High throughput | no | no |
CE57L_HUMAN | [view interactions] | High throughput | no | yes |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
JKIP1_HUMAN | [view interactions] | High throughput | no | no |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
ZC21A_HUMAN | [view interactions] | High throughput | no | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
DTX3_HUMAN | [view interactions] | High throughput | no | yes |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
ZN438_HUMAN | [view interactions] | High throughput | no | no |
SSR3_HUMAN | [view interactions] | High throughput | no | yes |
LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DOK2_HUMAN | [view interactions] | High throughput | no | no |
P55G_HUMAN | [view interactions] | High throughput | no | yes |
CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CBLC_HUMAN | [view interactions] | High throughput | no | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
GAB1_HUMAN | [view interactions] | High throughput | no | yes |
KIT_HUMAN | [view interactions] | High throughput | no | no |
MET_HUMAN | [view interactions] | High throughput | no | yes |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA1_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
LASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAXI_HUMAN | [view interactions] | High throughput | no | yes |
EFS_HUMAN | [view interactions] | High throughput | no | no |