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YES_HUMAN

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis. [View more on UniProt]

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No data found.

ELM instance Name Type Start End Partner
ELMI000133 MOD_TYR_CSK MOD 533 541 -
ELMI000133 MOD_TYR_CSK MOD 533 541 -

Molecular function

Term Name % Distance from the top of the tree Annotated in YES_HUMAN
GO:0043168 anion binding 41.3534 4 yes
GO:0000166 nucleotide binding 39.0977 4 yes
GO:0017076 purine nucleotide binding 39.0977 5 yes
GO:0032555 purine ribonucleotide binding 39.0977 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 39.0977 4 yes
GO:0019900 kinase binding 30.0752 4 no
GO:0019901 protein kinase binding 27.8195 5 no
GO:0005524 ATP binding 26.3158 5 yes
GO:0030554 adenyl nucleotide binding 26.3158 6 yes
GO:0032559 adenyl ribonucleotide binding 26.3158 5 yes
GO:0043169 cation binding 25.5639 4 no
GO:0046872 metal ion binding 25.5639 5 no
GO:0016462 pyrophosphatase activity 21.8045 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 21.8045 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 21.0526 6 no
GO:0016301 kinase activity 15.0376 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 15.0376 4 yes
GO:0004713 protein tyrosine kinase activity 11.2782 4 yes
GO:0004715 non-membrane spanning protein tyrosine kinase activity 7.5188 5 yes
GO:0045309 protein phosphorylated amino acid binding 6.7669 4 yes
GO:0001784 phosphotyrosine residue binding 6.0150 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in YES_HUMAN
GO:0048522 positive regulation of cellular process 72.9323 4 yes
GO:0031323 regulation of cellular metabolic process 61.6541 4 yes
GO:0060255 regulation of macromolecule metabolic process 60.9023 4 yes
GO:0080090 regulation of primary metabolic process 54.1353 4 yes
GO:0048523 negative regulation of cellular process 53.3835 4 no
GO:0051128 regulation of cellular component organization 53.3835 4 no
GO:0009893 positive regulation of metabolic process 51.8797 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 50.3759 5 yes
GO:0010646 regulation of cell communication 47.3684 4 no
GO:0009889 regulation of biosynthetic process 47.3684 4 yes
GO:0031325 positive regulation of cellular metabolic process 47.3684 5 yes
GO:0031326 regulation of cellular biosynthetic process 47.3684 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 46.6165 5 yes
GO:0022607 cellular component assembly 45.1128 4 no
GO:0051246 regulation of protein metabolic process 44.3609 5 yes
GO:0010468 regulation of gene expression 42.8571 6 yes
GO:0051049 regulation of transport 40.6015 4 yes
GO:0008104 protein localization 40.6015 4 no
GO:0009966 regulation of signal transduction 40.6015 4 no
GO:0048584 positive regulation of response to stimulus 39.8496 4 yes
GO:0051247 positive regulation of protein metabolic process 38.3459 6 yes
GO:0006996 organelle organization 38.3459 4 no
GO:0031399 regulation of protein modification process 34.5865 6 yes
GO:0010647 positive regulation of cell communication 33.8346 5 no
GO:0023056 positive regulation of signaling 33.8346 4 no
GO:0009891 positive regulation of biosynthetic process 33.0827 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 33.0827 6 yes
GO:0051174 regulation of phosphorus metabolic process 32.3308 5 yes
GO:0060341 regulation of cellular localization 32.3308 4 no
GO:0019220 regulation of phosphate metabolic process 32.3308 6 yes
GO:0044087 regulation of cellular component biogenesis 31.5789 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 31.5789 6 yes
GO:0042325 regulation of phosphorylation 30.8271 7 yes
GO:0032880 regulation of protein localization 30.8271 5 no
GO:1902531 regulation of intracellular signal transduction 30.8271 5 no
GO:0009967 positive regulation of signal transduction 30.8271 5 no
GO:0001932 regulation of protein phosphorylation 30.8271 7 yes
GO:0009892 negative regulation of metabolic process 30.0752 4 no
GO:0033043 regulation of organelle organization 29.3233 5 no
GO:0051130 positive regulation of cellular component organization 29.3233 5 no
GO:0071702 organic substance transport 29.3233 4 no
GO:0031324 negative regulation of cellular metabolic process 29.3233 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 29.3233 5 yes
GO:0031401 positive regulation of protein modification process 29.3233 7 yes
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0045937 positive regulation of phosphate metabolic process 27.8195 7 yes
GO:0051240 positive regulation of multicellular organismal process 27.8195 4 yes
GO:0030030 cell projection organization 27.8195 4 no
GO:0010562 positive regulation of phosphorus metabolic process 27.8195 6 yes
GO:0042327 positive regulation of phosphorylation 27.0677 8 yes
GO:0071705 nitrogen compound transport 27.0677 4 no
GO:0043067 regulation of programmed cell death 27.0677 4 no
GO:0001934 positive regulation of protein phosphorylation 27.0677 8 yes
GO:0042981 regulation of apoptotic process 25.5639 5 no
GO:0120036 plasma membrane bounded cell projection organization 25.5639 5 no
GO:0042127 regulation of cell population proliferation 24.8120 4 no
GO:0030334 regulation of cell migration 24.0602 5 no
GO:2000145 regulation of cell motility 24.0602 4 no
GO:0043085 positive regulation of catalytic activity 24.0602 4 no
GO:0030155 regulation of cell adhesion 24.0602 4 yes
GO:0036211 protein modification process 23.3083 4 yes
GO:0043412 macromolecule modification 23.3083 4 yes
GO:0051252 regulation of RNA metabolic process 23.3083 5 yes
GO:0071310 cellular response to organic substance 23.3083 4 yes
GO:0043933 protein-containing complex organization 23.3083 4 no
GO:0031344 regulation of cell projection organization 23.3083 5 no
GO:0002684 positive regulation of immune system process 23.3083 4 yes
GO:0015031 protein transport 22.5564 4 no
GO:0010628 positive regulation of gene expression 22.5564 7 no
GO:1902533 positive regulation of intracellular signal transduction 22.5564 6 no
GO:0009890 negative regulation of biosynthetic process 22.5564 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.5564 6 no
GO:0032101 regulation of response to external stimulus 22.5564 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 21.8045 4 no
GO:0051094 positive regulation of developmental process 21.8045 4 no
GO:1903829 positive regulation of protein localization 21.8045 5 no
GO:0051050 positive regulation of transport 21.8045 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.8045 6 no
GO:0031327 negative regulation of cellular biosynthetic process 21.8045 6 no
GO:0006796 phosphate-containing compound metabolic process 21.8045 4 yes
GO:0045595 regulation of cell differentiation 21.0526 4 no
GO:2001141 regulation of RNA biosynthetic process 20.3008 6 yes
GO:0065003 protein-containing complex assembly 20.3008 5 no
GO:2000026 regulation of multicellular organismal development 20.3008 4 no
GO:0051493 regulation of cytoskeleton organization 20.3008 6 no
GO:0060627 regulation of vesicle-mediated transport 20.3008 4 no
GO:0051338 regulation of transferase activity 20.3008 4 no
GO:0061024 membrane organization 20.3008 4 no
GO:0006355 regulation of DNA-templated transcription 20.3008 7 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 19.5489 5 yes
GO:0050776 regulation of immune response 19.5489 4 yes
GO:0048585 negative regulation of response to stimulus 18.7970 4 yes
GO:0080134 regulation of response to stress 18.7970 4 yes
GO:0050778 positive regulation of immune response 17.2932 5 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 17.2932 4 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 17.2932 5 yes
GO:0045785 positive regulation of cell adhesion 15.7895 5 yes
GO:0031347 regulation of defense response 15.7895 5 yes
GO:0016310 phosphorylation 15.0376 5 yes
GO:0022407 regulation of cell-cell adhesion 14.2857 5 yes
GO:0051254 positive regulation of RNA metabolic process 13.5338 6 yes
GO:1901701 cellular response to oxygen-containing compound 13.5338 4 yes
GO:0050865 regulation of cell activation 12.7820 4 yes
GO:0002694 regulation of leukocyte activation 12.7820 4 yes
GO:0006357 regulation of transcription by RNA polymerase II 12.7820 8 yes
GO:0051249 regulation of lymphocyte activation 12.0301 5 yes
GO:0071363 cellular response to growth factor stimulus 12.0301 4 yes
GO:0045893 positive regulation of DNA-templated transcription 11.2782 8 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 11.2782 8 yes
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 11.2782 9 yes
GO:0050863 regulation of T cell activation 11.2782 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 11.2782 7 yes
GO:0033993 response to lipid 10.5263 4 yes
GO:0034762 regulation of transmembrane transport 10.5263 4 yes
GO:0022409 positive regulation of cell-cell adhesion 10.5263 6 yes
GO:0140546 defense response to symbiont 9.7744 4 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 9.7744 6 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.7744 4 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 9.7744 4 yes
GO:0050867 positive regulation of cell activation 9.0226 5 yes
GO:0051251 positive regulation of lymphocyte activation 9.0226 6 yes
GO:0071396 cellular response to lipid 9.0226 5 yes
GO:0002683 negative regulation of immune system process 9.0226 4 yes
GO:0002696 positive regulation of leukocyte activation 9.0226 5 yes
GO:0050870 positive regulation of T cell activation 8.2707 7 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 8.2707 7 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 7.5188 9 yes
GO:0050727 regulation of inflammatory response 7.5188 5 yes
GO:0038093 Fc receptor signaling pathway 6.7669 5 yes
GO:0032102 negative regulation of response to external stimulus 6.7669 5 yes
GO:0038094 Fc-gamma receptor signaling pathway 6.0150 6 yes
GO:0048013 ephrin receptor signaling pathway 6.0150 6 yes
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 5.2632 4 yes
GO:0050728 negative regulation of inflammatory response 5.2632 6 yes
GO:0002431 Fc receptor mediated stimulatory signaling pathway 5.2632 5 yes
GO:0031348 negative regulation of defense response 5.2632 5 yes
GO:0050777 negative regulation of immune response 4.5113 5 yes
GO:0002861 regulation of inflammatory response to antigenic stimulus 4.5113 5 yes
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 4.5113 6 yes
GO:0003018 vascular process in circulatory system 4.5113 4 yes
GO:0071559 response to transforming growth factor beta 3.7594 4 yes
GO:0071560 cellular response to transforming growth factor beta stimulus 3.7594 5 yes
GO:0032526 response to retinoic acid 3.0075 4 yes
GO:0036119 response to platelet-derived growth factor 3.0075 4 yes
GO:0036120 cellular response to platelet-derived growth factor stimulus 3.0075 5 yes
GO:0071300 cellular response to retinoic acid 3.0075 5 yes
GO:0010827 regulation of glucose transmembrane transport 2.2556 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NPHN_HUMAN [view interactions] Low throughput no no
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
OCLN_HUMAN [view interactions] Low throughput no no
RASA1_HUMAN [view interactions] Low throughput no yes
CD36_HUMAN [view interactions] Low throughput no no
PECA1_HUMAN [view interactions] Low throughput no no
TRPV4_HUMAN [view interactions] Low throughput no yes
MCP_HUMAN [view interactions] Low throughput no no
DIAP1_HUMAN [view interactions] Low throughput no yes
EDNRA_HUMAN [view interactions] Low throughput no yes
DAB1_HUMAN [view interactions] Low throughput no yes
ACSL3_HUMAN [view entry] [view interactions] Low throughput yes yes
JAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
SRC8_HUMAN [view entry] [view interactions] Low throughput yes yes
SHC1_HUMAN [view entry] [view interactions] Low throughput yes yes
P85A_HUMAN [view interactions] Low throughput no yes
IL1R1_HUMAN [view interactions] Low throughput no no
GPVI_HUMAN [view interactions] Low throughput no no
CBL_HUMAN [view interactions] Low throughput no yes
ACK1_HUMAN [view entry] [view interactions] Low throughput yes yes
SOCS1_HUMAN [view interactions] Low throughput no yes
MED28_HUMAN [view interactions] Low throughput no yes
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRE_HUMAN [view interactions] Low throughput no no
FLOT1_HUMAN [view entry] [view interactions] Low throughput yes yes
CSF1R_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
NHRF1_HUMAN [view interactions] Low throughput no no
RL10_HUMAN [view entry] [view interactions] Low throughput yes yes
PGFRB_HUMAN [view interactions] Low throughput no yes
FGFR1_HUMAN [view entry] [view interactions] Low throughput yes yes
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
EPHB2_HUMAN [view entry] [view interactions] Low throughput yes yes
OGT1_HUMAN [view entry] [view interactions] Low throughput yes yes
TNR6_HUMAN [view interactions] Low throughput no no
NCOA2_HUMAN [view interactions] Low throughput no no
CDCP1_HUMAN [view interactions] Low throughput no yes
YAP1_HUMAN [view interactions] Low throughput no yes
VGFR1_HUMAN [view interactions] Low throughput no no
CDN1B_HUMAN [view interactions] Low throughput no yes
LOX5_HUMAN [view interactions] Low throughput no no
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
SPR2A_HUMAN [view interactions] Low throughput no no
KHDR1_HUMAN [view interactions] Low throughput no yes
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
CPSF6_HUMAN [view interactions] High throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
TRIM5_HUMAN [view interactions] High throughput no yes
CCD33_HUMAN [view interactions] High throughput no no
FACC1_HUMAN [view interactions] High throughput no no
CEP83_HUMAN [view interactions] High throughput no yes
DEN2C_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
CARD9_HUMAN [view interactions] High throughput no no
TRI69_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
PAN2_HUMAN [view interactions] High throughput no no
CUL7_HUMAN [view interactions] High throughput no yes
GPR35_HUMAN [view interactions] High throughput no no
GRPE2_HUMAN [view interactions] High throughput no yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
UIF_HUMAN [view interactions] High throughput no yes
IKBA_HUMAN [view interactions] High throughput no yes
ANR12_HUMAN [view interactions] High throughput no yes
ZNT4_HUMAN [view interactions] High throughput no no
JSPR1_HUMAN [view interactions] High throughput no no
MOT14_HUMAN [view interactions] High throughput no yes
CP51A_HUMAN [view interactions] High throughput no no
CMAP3_HUMAN [view interactions] High throughput no no
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
BMR1A_HUMAN [view interactions] High throughput no no
CALL3_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
CP2S1_HUMAN [view interactions] High throughput no no
DUS22_HUMAN [view interactions] High throughput no yes
NICA_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
TNFL6_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
IRS4_HUMAN [view interactions] High throughput no no
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
ASAP2_HUMAN [view interactions] High throughput no yes
YES_HUMAN [view entry] [view interactions] High throughput yes yes
IF4G3_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
DEN2B_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
MAMD1_HUMAN [view interactions] High throughput no no
NUPR1_HUMAN [view interactions] High throughput no no
PEAR1_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
MYPN_HUMAN [view interactions] High throughput no no
SHIP1_HUMAN [view interactions] High throughput no no
FA20C_HUMAN [view interactions] High throughput no no
RBM33_HUMAN [view interactions] High throughput no yes
CERS2_HUMAN [view interactions] High throughput no no
DMRTB_HUMAN [view interactions] High throughput no no
MALL_HUMAN [view interactions] High throughput no no
SAM11_HUMAN [view interactions] High throughput no no
CENPM_HUMAN [view interactions] High throughput no yes
RBM15_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
TEN1_HUMAN [view interactions] High throughput no no
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
IFT52_HUMAN [view interactions] High throughput no no
FA13A_HUMAN [view interactions] High throughput no yes
ZPBP2_HUMAN [view interactions] High throughput no no
Z512B_HUMAN [view interactions] High throughput no yes
CEP15_HUMAN [view interactions] High throughput no yes
DVL2_HUMAN [view interactions] High throughput no yes
CENPK_HUMAN [view interactions] High throughput no no
UT1_HUMAN [view interactions] High throughput no no
OPALI_HUMAN [view interactions] High throughput no yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
WDR36_HUMAN [view interactions] High throughput no no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
FFAR1_HUMAN [view interactions] High throughput no no
FLNB_HUMAN [view interactions] High throughput no no
CEP43_HUMAN [view interactions] High throughput no no
LIMA1_HUMAN [view entry] [view interactions] High throughput yes no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
ZDH23_HUMAN [view interactions] High throughput no no
SIDT2_HUMAN [view interactions] High throughput no yes
STOM_HUMAN [view entry] [view interactions] High throughput yes yes
DREB_HUMAN [view entry] [view interactions] High throughput yes yes
PCDB3_HUMAN [view interactions] High throughput no no
SODC_HUMAN [view interactions] High throughput no yes
CAMKV_HUMAN [view entry] [view interactions] High throughput yes yes
KSR1_HUMAN [view interactions] High throughput no yes
XRP2_HUMAN [view entry] [view interactions] High throughput yes no
MED21_HUMAN [view interactions] High throughput no yes
ZCHC9_HUMAN [view interactions] High throughput no yes
HXB5_HUMAN [view interactions] High throughput no no
TMM59_HUMAN [view interactions] High throughput no yes
CXB7_HUMAN [view interactions] High throughput no no
CDK20_HUMAN [view interactions] High throughput no yes
S2541_HUMAN [view interactions] High throughput no no
PAL4C_HUMAN [view interactions] High throughput no no
AIP_HUMAN [view entry] [view interactions] High throughput yes yes
PAL4G_HUMAN [view interactions] High throughput no no
PAI2_HUMAN [view interactions] High throughput no no
SYT3_HUMAN [view entry] [view interactions] High throughput yes no
FGR_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
ZFY27_HUMAN [view interactions] High throughput no yes
H90B4_HUMAN [view interactions] High throughput no no
PAR2_HUMAN [view entry] [view interactions] High throughput yes yes
H90B3_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
HS905_HUMAN [view interactions] High throughput no no
GPC5B_HUMAN [view entry] [view interactions] High throughput yes no
HS904_HUMAN [view interactions] High throughput no no
RBBP6_HUMAN [view interactions] High throughput no yes
CC186_HUMAN [view interactions] High throughput no yes
ST38L_HUMAN [view entry] [view interactions] High throughput yes yes
KIFA3_HUMAN [view entry] [view interactions] High throughput yes yes
TGFR2_HUMAN [view interactions] High throughput no no
CCNL2_HUMAN [view interactions] High throughput no yes
NAT10_HUMAN [view interactions] High throughput no yes
T185A_HUMAN [view interactions] High throughput no no
BLMH_HUMAN [view interactions] High throughput no yes
C1QL4_HUMAN [view interactions] High throughput no no
SNG1_HUMAN [view entry] [view interactions] High throughput yes yes
PCDGK_HUMAN [view interactions] High throughput no yes
KC1G2_HUMAN [view interactions] High throughput no yes
PRUN2_HUMAN [view entry] [view interactions] High throughput yes yes
VA0D2_HUMAN [view interactions] High throughput no no
ACBD7_HUMAN [view interactions] High throughput no no
TBD_HUMAN [view interactions] High throughput no yes
CCR1_HUMAN [view interactions] High throughput no no
NPC2_HUMAN [view interactions] High throughput no yes
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
PIGM_HUMAN [view interactions] High throughput no no
OCRL_HUMAN [view interactions] High throughput no yes
FRIH_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
FLRT1_HUMAN [view interactions] High throughput no no
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
ERLEC_HUMAN [view interactions] High throughput no yes
RSMN_HUMAN [view interactions] High throughput no yes
LTOR2_HUMAN [view interactions] High throughput no yes
RSMB_HUMAN [view interactions] High throughput no yes
KCNE3_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
SPIN1_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
KC1G3_HUMAN [view interactions] High throughput no yes
KPCD1_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
BCLF1_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
SPF45_HUMAN [view interactions] High throughput no yes
IFM3_HUMAN [view interactions] High throughput no yes
CHERP_HUMAN [view interactions] High throughput no no
SIK2_HUMAN [view interactions] High throughput no yes
SF3A1_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SF3B3_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
SF3B2_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
ERH_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
RHOQ_HUMAN [view interactions] High throughput no no
HNRC1_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPC_HUMAN [view interactions] High throughput no yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
CDK1_HUMAN [view interactions] High throughput no no
RHOC_HUMAN [view interactions] High throughput no no
SF3B1_HUMAN [view interactions] High throughput no yes
RHOD_HUMAN [view interactions] High throughput no no
DHX15_HUMAN [view interactions] High throughput no yes
RHOF_HUMAN [view interactions] High throughput no no
SR140_HUMAN [view interactions] High throughput no yes
RHOU_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
RHOH_HUMAN [view interactions] High throughput no yes
NF2L2_HUMAN [view interactions] High throughput no yes
RND1_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
RCBT2_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
MYCN_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA2_HUMAN [view interactions] High throughput no yes
HDAC6_HUMAN [view interactions] High throughput no yes
DDR1_HUMAN [view interactions] High throughput no yes
CLD4_HUMAN [view interactions] High throughput no yes
RB27A_HUMAN [view interactions] High throughput no yes
GBRA1_HUMAN [view entry] [view interactions] High throughput yes yes
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
EHD4_HUMAN [view entry] [view interactions] High throughput yes no
KMT2A_HUMAN [view interactions] High throughput no yes
PGM1_HUMAN [view interactions] High throughput no no
ANR54_HUMAN [view interactions] High throughput no yes
PRP4B_HUMAN [view interactions] High throughput no yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
PTN11_HUMAN [view entry] [view interactions] High throughput yes yes
TUTLB_HUMAN [view entry] [view interactions] High throughput yes no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
MSI2H_HUMAN [view interactions] High throughput no yes
ERBB3_HUMAN [view interactions] High throughput no yes
PEX2_HUMAN [view interactions] High throughput no yes
ERBB4_HUMAN [view entry] [view interactions] High throughput yes yes
RPA1_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
FLT3_HUMAN [view interactions] High throughput no no
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRA_HUMAN [view interactions] High throughput no no
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
PHAG1_HUMAN [view interactions] High throughput no yes
LTOR3_HUMAN [view interactions] High throughput no yes
M4K4_HUMAN [view interactions] High throughput no yes
SNX9_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC2_HUMAN [view interactions] High throughput no yes
SPRE_HUMAN [view interactions] High throughput no yes
SHC2_HUMAN [view interactions] High throughput no yes
MIDN_HUMAN [view interactions] High throughput no no
SHF_HUMAN [view interactions] High throughput no no
HCK_HUMAN [view entry] [view interactions] High throughput yes no
SHIP2_HUMAN [view interactions] High throughput no yes
SLAP1_HUMAN [view interactions] High throughput no yes
DOK1_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] High throughput yes no
STAP2_HUMAN [view interactions] High throughput no yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
TENS3_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
TXK_HUMAN [view interactions] High throughput no no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
MBP_HUMAN [view entry] [view interactions] High throughput yes no
GELS_HUMAN [view entry] [view interactions] High throughput yes no
SKAP2_HUMAN [view interactions] High throughput no no
LEG7_HUMAN [view interactions] High throughput no no
DYLT1_HUMAN [view interactions] High throughput no no
SPB4_HUMAN [view interactions] High throughput no no
SNP23_HUMAN [view entry] [view interactions] High throughput yes no
KCC2G_HUMAN [view entry] [view interactions] High throughput yes yes
FAF2_HUMAN [view interactions] High throughput no yes
DSC3_HUMAN [view interactions] High throughput no no
TSR1_HUMAN [view interactions] High throughput no no
ECM1_HUMAN [view interactions] High throughput no no
ILF2_HUMAN [view interactions] High throughput no yes
SYT6_HUMAN [view entry] [view interactions] High throughput yes no
VATE1_HUMAN [view entry] [view interactions] High throughput yes yes
POF1B_HUMAN [view interactions] High throughput no no
NSUN2_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
AGM1_HUMAN [view interactions] High throughput no no
PIM3_HUMAN [view interactions] High throughput no no
GLNA_HUMAN [view entry] [view interactions] High throughput yes yes
HASP_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
OLA1_HUMAN [view entry] [view interactions] High throughput yes yes
ADA15_HUMAN [view interactions] High throughput no yes
ERAP1_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
KS6A2_HUMAN [view interactions] High throughput no yes
DNJ5B_HUMAN [view interactions] High throughput no no
DNJC5_HUMAN [view interactions] High throughput no yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
B3GA1_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CXAR_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
OLIG1_HUMAN [view interactions] High throughput no no
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
BECN1_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
SOCS3_HUMAN [view interactions] High throughput no yes
CXD3_HUMAN [view interactions] High throughput no no
FXR2_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
TRAF2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
CA094_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
FUND1_HUMAN [view interactions] High throughput no yes
LMAN1_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT8A_HUMAN [view interactions] High throughput no yes
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
SSBP3_HUMAN [view interactions] High throughput no no
AFAD_HUMAN [view entry] [view interactions] High throughput yes yes
THAP1_HUMAN [view interactions] High throughput no no
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
NIF3L_HUMAN [view interactions] High throughput no yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF6_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
CRTP1_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
IKZF3_HUMAN [view interactions] High throughput no no
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A2_HUMAN [view interactions] High throughput no yes
RAB9A_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
STX6_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
AMOL2_HUMAN [view interactions] High throughput no no
ZFPL1_HUMAN [view interactions] High throughput no yes
CBLB_HUMAN [view entry] [view interactions] High throughput yes yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
SHLB2_HUMAN [view entry] [view interactions] High throughput yes no
DPP4_HUMAN [view interactions] High throughput no no
DESM_HUMAN [view entry] [view interactions] High throughput yes no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CHM1A_HUMAN [view entry] [view interactions] High throughput yes no
MLP3B_HUMAN [view interactions] High throughput no yes
SOCS7_HUMAN [view interactions] High throughput no yes
CACO2_HUMAN [view interactions] High throughput no yes
GFAP_HUMAN [view entry] [view interactions] High throughput yes no
SLN11_HUMAN [view interactions] High throughput no yes
T10IP_HUMAN [view interactions] High throughput no no
DTX2_HUMAN [view interactions] High throughput no yes
DRC4_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
DDT4L_HUMAN [view interactions] High throughput no no
RAB25_HUMAN [view interactions] High throughput no no
CE57L_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
JKIP1_HUMAN [view interactions] High throughput no no
RFA1_HUMAN [view interactions] High throughput no yes
ZC21A_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
DTX3_HUMAN [view interactions] High throughput no yes
MUC18_HUMAN [view interactions] High throughput no yes
ZN438_HUMAN [view interactions] High throughput no no
SSR3_HUMAN [view interactions] High throughput no yes
LIN7C_HUMAN [view entry] [view interactions] High throughput yes yes
SOCS2_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
DOK2_HUMAN [view interactions] High throughput no no
P55G_HUMAN [view interactions] High throughput no yes
CRKL_HUMAN [view entry] [view interactions] High throughput yes yes
CBLC_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
ANDR_HUMAN [view interactions] High throughput no no
GAB1_HUMAN [view interactions] High throughput no yes
KIT_HUMAN [view interactions] High throughput no no
MET_HUMAN [view interactions] High throughput no yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
TMM17_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
PSA1_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
KCNK3_HUMAN [view interactions] High throughput no no
LASP1_HUMAN [view entry] [view interactions] High throughput yes yes
PAXI_HUMAN [view interactions] High throughput no yes
EFS_HUMAN [view interactions] High throughput no no