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LCK_HUMAN

Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway. Once stimulated, the TCR recruits the tyrosine kinase ZAP70, that becomes phosphorylated and activated by LCK. Following this, a large number of signaling molecules are recruited, ultimately leading to lymphokine production. LCK also contributes to signaling by other receptor molecules. Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK. Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response. Binding of IL2 to its receptor results in increased activity of LCK. Is expressed at all stages of thymocyte development and is required for the regulation of maturation events that are governed by both pre-TCR and mature alpha beta TCR. Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, RHOH or TYROBP. Interacts with FYB2 (PubMed). [View more on UniProt]

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Position Amino acid Mutation Disease Overlap with binding region
341 Leu Pro Immunodeficiency22(IMD22) -
ELM instance Name Type Start End Partner
ELMI000316 MOD_SPalmitoyl_4 MOD 1 7 -

Molecular function

Term Name % Distance from the top of the tree Annotated in LCK_HUMAN
GO:0017076 purine nucleotide binding 38.7665 4 yes
GO:0032555 purine ribonucleotide binding 37.8855 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 37.8855 4 yes
GO:0030554 adenyl nucleotide binding 32.1586 5 yes
GO:0005524 ATP binding 31.2775 5 yes
GO:0032559 adenyl ribonucleotide binding 31.2775 5 yes
GO:0019900 kinase binding 24.6696 4 yes
GO:0019901 protein kinase binding 23.3480 5 yes
GO:0046872 metal ion binding 20.7048 4 no
GO:0045296 cadherin binding 20.7048 4 no
GO:0016301 kinase activity 19.3833 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 18.9427 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 17.1806 4 yes
GO:0004713 protein tyrosine kinase activity 9.2511 4 yes
GO:0001784 phosphotyrosine residue binding 6.1674 5 yes
GO:0019902 phosphatase binding 6.1674 4 yes
GO:0042578 phosphoric ester hydrolase activity 6.1674 4 yes
GO:0045309 protein phosphorylated amino acid binding 6.1674 4 yes
GO:0004715 non-membrane spanning protein tyrosine kinase activity 5.2863 5 yes
GO:0016791 phosphatase activity 5.2863 5 yes
GO:0019903 protein phosphatase binding 4.8458 5 yes
GO:0042169 SH2 domain binding 3.9648 4 yes
GO:0043274 phospholipase binding 2.6432 4 yes
GO:0004722 protein serine/threonine phosphatase activity 2.2026 4 yes
GO:0016004 phospholipase activator activity 1.7621 5 yes
GO:0060229 lipase activator activity 1.7621 4 yes
GO:0051117 ATPase binding 1.3216 4 yes
GO:0042609 CD4 receptor binding 0.8811 4 yes
GO:0042610 CD8 receptor binding 0.8811 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in LCK_HUMAN
GO:0048522 positive regulation of cellular process 59.9119 4 yes
GO:0060255 regulation of macromolecule metabolic process 51.5419 4 yes
GO:0080090 regulation of primary metabolic process 49.3392 4 yes
GO:0031323 regulation of cellular metabolic process 48.8987 4 no
GO:0051171 regulation of nitrogen compound metabolic process 48.4581 4 yes
GO:0048523 negative regulation of cellular process 48.0176 4 yes
GO:0009893 positive regulation of metabolic process 44.0529 4 yes
GO:0010646 regulation of cell communication 43.6123 4 yes
GO:0009966 regulation of signal transduction 41.8502 4 yes
GO:0051128 regulation of cellular component organization 41.4097 4 no
GO:0010604 positive regulation of macromolecule metabolic process 40.9692 5 yes
GO:0031325 positive regulation of cellular metabolic process 38.7665 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 37.4449 5 yes
GO:0010468 regulation of gene expression 37.0044 5 no
GO:0051246 regulation of protein metabolic process 34.3612 5 yes
GO:0009889 regulation of biosynthetic process 34.3612 4 no
GO:0031326 regulation of cellular biosynthetic process 33.9207 5 no
GO:0022607 cellular component assembly 33.4802 4 no
GO:0010556 regulation of macromolecule biosynthetic process 33.0396 5 no
GO:0006996 organelle organization 33.0396 4 no
GO:1902531 regulation of intracellular signal transduction 32.5991 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 32.1586 5 no
GO:0048584 positive regulation of response to stimulus 31.2775 4 yes
GO:0008104 protein localization 30.3965 4 no
GO:0031399 regulation of protein modification process 29.5154 6 no
GO:0071310 cellular response to organic substance 29.0749 4 no
GO:0010941 regulation of cell death 28.6344 4 yes
GO:0006796 phosphate-containing compound metabolic process 28.6344 4 yes
GO:0010647 positive regulation of cell communication 27.3128 5 yes
GO:0023056 positive regulation of signaling 27.3128 4 yes
GO:0051247 positive regulation of protein metabolic process 27.3128 6 yes
GO:0019220 regulation of phosphate metabolic process 27.3128 6 no
GO:0051174 regulation of phosphorus metabolic process 27.3128 5 no
GO:0042981 regulation of apoptotic process 26.8722 6 yes
GO:0043067 regulation of programmed cell death 26.8722 5 yes
GO:0043412 macromolecule modification 26.8722 4 yes
GO:0051049 regulation of transport 26.8722 4 no
GO:0036211 protein modification process 26.4317 4 yes
GO:0009892 negative regulation of metabolic process 26.4317 4 no
GO:0042325 regulation of phosphorylation 26.4317 7 no
GO:0043085 positive regulation of catalytic activity 25.5507 4 yes
GO:0051252 regulation of RNA metabolic process 25.1101 5 no
GO:0030030 cell projection organization 25.1101 4 no
GO:0009967 positive regulation of signal transduction 25.1101 5 yes
GO:0006355 regulation of DNA-templated transcription 24.6696 6 no
GO:0010605 negative regulation of macromolecule metabolic process 24.6696 5 no
GO:1903506 regulation of nucleic acid-templated transcription 24.6696 7 no
GO:2001141 regulation of RNA biosynthetic process 24.6696 6 no
GO:0060341 regulation of cellular localization 24.6696 4 no
GO:0033043 regulation of organelle organization 24.2291 5 no
GO:0001932 regulation of protein phosphorylation 23.7885 7 no
GO:0071705 nitrogen compound transport 23.7885 4 no
GO:0044087 regulation of cellular component biogenesis 23.7885 4 no
GO:0051130 positive regulation of cellular component organization 23.7885 5 no
GO:0051338 regulation of transferase activity 23.3480 4 no
GO:0071702 organic substance transport 23.3480 4 no
GO:0042127 regulation of cell population proliferation 23.3480 4 no
GO:0045595 regulation of cell differentiation 22.9075 4 no
GO:0032880 regulation of protein localization 22.9075 5 no
GO:0009891 positive regulation of biosynthetic process 22.9075 5 no
GO:0031328 positive regulation of cellular biosynthetic process 22.9075 6 no
GO:0030155 regulation of cell adhesion 22.4670 4 yes
GO:0016192 vesicle-mediated transport 22.0264 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 22.0264 6 no
GO:0080134 regulation of response to stress 22.0264 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 21.5859 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.5859 6 no
GO:0007167 enzyme-linked receptor protein signaling pathway 21.5859 4 yes
GO:0048585 negative regulation of response to stimulus 21.1454 4 no
GO:2000026 regulation of multicellular organismal development 21.1454 4 no
GO:0007010 cytoskeleton organization 20.7048 5 no
GO:0016310 phosphorylation 20.2643 5 yes
GO:0010562 positive regulation of phosphorus metabolic process 20.2643 6 no
GO:0010648 negative regulation of cell communication 20.2643 5 no
GO:0023057 negative regulation of signaling 20.2643 4 no
GO:0031401 positive regulation of protein modification process 20.2643 7 no
GO:0045937 positive regulation of phosphate metabolic process 20.2643 7 no
GO:0022603 regulation of anatomical structure morphogenesis 20.2643 4 no
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 20.2643 5 yes
GO:1902533 positive regulation of intracellular signal transduction 18.9427 6 yes
GO:0051336 regulation of hydrolase activity 18.0617 4 yes
GO:0002684 positive regulation of immune system process 18.0617 4 yes
GO:0006468 protein phosphorylation 17.1806 5 yes
GO:0050776 regulation of immune response 16.7401 4 yes
GO:0018193 peptidyl-amino acid modification 14.9780 5 yes
GO:0045785 positive regulation of cell adhesion 14.9780 5 yes
GO:0022407 regulation of cell-cell adhesion 13.6564 5 yes
GO:0010942 positive regulation of cell death 13.2159 5 yes
GO:0050865 regulation of cell activation 13.2159 4 yes
GO:0002694 regulation of leukocyte activation 12.3348 4 yes
GO:0030162 regulation of proteolysis 11.8943 6 yes
GO:0051249 regulation of lymphocyte activation 11.8943 5 yes
GO:0051345 positive regulation of hydrolase activity 11.8943 5 yes
GO:0043065 positive regulation of apoptotic process 11.4537 7 yes
GO:0043068 positive regulation of programmed cell death 11.4537 6 yes
GO:0050778 positive regulation of immune response 11.0132 5 yes
GO:0050863 regulation of T cell activation 11.0132 6 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 10.1322 6 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 10.1322 4 yes
GO:0045862 positive regulation of proteolysis 9.6916 7 yes
GO:0022409 positive regulation of cell-cell adhesion 9.2511 6 yes
GO:2001233 regulation of apoptotic signaling pathway 9.2511 5 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.2511 4 yes
GO:0050867 positive regulation of cell activation 8.8106 5 yes
GO:0051251 positive regulation of lymphocyte activation 8.8106 6 yes
GO:0002696 positive regulation of leukocyte activation 8.8106 5 yes
GO:0048878 chemical homeostasis 8.3700 4 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 8.3700 7 yes
GO:0050870 positive regulation of T cell activation 7.9295 7 yes
GO:0052547 regulation of peptidase activity 7.9295 5 yes
GO:0052548 regulation of endopeptidase activity 7.9295 6 yes
GO:0006811 ion transport 7.4890 4 yes
GO:0018108 peptidyl-tyrosine phosphorylation 7.0485 6 yes
GO:0018212 peptidyl-tyrosine modification 7.0485 6 yes
GO:2000116 regulation of cysteine-type endopeptidase activity 6.1674 7 yes
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 5.7269 8 yes
GO:0006812 cation transport 5.7269 5 yes
GO:0010950 positive regulation of endopeptidase activity 5.2863 7 yes
GO:0010952 positive regulation of peptidase activity 5.2863 6 yes
GO:0050851 antigen receptor-mediated signaling pathway 4.8458 5 yes
GO:0030001 metal ion transport 4.4053 6 yes
GO:0050801 ion homeostasis 4.4053 5 yes
GO:2001235 positive regulation of apoptotic signaling pathway 4.4053 6 yes
GO:0048534 hematopoietic or lymphoid organ development 3.9648 4 yes
GO:0050852 T cell receptor signaling pathway 3.9648 6 yes
GO:0051282 regulation of sequestering of calcium ion 3.9648 4 yes
GO:0055080 cation homeostasis 3.9648 6 yes
GO:0098771 inorganic ion homeostasis 3.9648 6 yes
GO:2001242 regulation of intrinsic apoptotic signaling pathway 3.9648 6 yes
GO:0030003 cellular cation homeostasis 3.5242 5 yes
GO:0042110 T cell activation 3.5242 4 yes
GO:2001056 positive regulation of cysteine-type endopeptidase activity 3.5242 8 yes
GO:0002521 leukocyte differentiation 3.5242 4 yes
GO:0006873 cellular ion homeostasis 3.5242 4 yes
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 3.0837 9 yes
GO:0055065 metal ion homeostasis 3.0837 7 yes
GO:1903131 mononuclear cell differentiation 3.0837 5 yes
GO:0030098 lymphocyte differentiation 2.6432 4 yes
GO:0050853 B cell receptor signaling pathway 2.6432 6 yes
GO:0072507 divalent inorganic cation homeostasis 2.6432 7 yes
GO:0098655 cation transmembrane transport 2.6432 4 yes
GO:0006816 calcium ion transport 2.6432 7 yes
GO:0006875 cellular metal ion homeostasis 2.6432 6 yes
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2.6432 10 yes
GO:0034114 regulation of heterotypic cell-cell adhesion 2.2026 6 yes
GO:0050854 regulation of antigen receptor-mediated signaling pathway 2.2026 5 yes
GO:0072503 cellular divalent inorganic cation homeostasis 2.2026 6 yes
GO:0098660 inorganic ion transmembrane transport 2.2026 4 yes
GO:0098662 inorganic cation transmembrane transport 2.2026 5 yes
GO:0030217 T cell differentiation 1.7621 5 yes
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.7621 7 yes
GO:0050856 regulation of T cell receptor signaling pathway 1.7621 6 yes
GO:0070588 calcium ion transmembrane transport 1.7621 6 yes
GO:0030097 hemopoiesis 1.3216 5 yes
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1.3216 6 yes
GO:0050862 positive regulation of T cell receptor signaling pathway 1.3216 7 yes
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 1.3216 7 yes
GO:0046916 cellular transition metal ion homeostasis 0.8811 7 yes
GO:0051209 release of sequestered calcium ion into cytosol 0.8811 6 yes
GO:0051283 negative regulation of sequestering of calcium ion 0.8811 5 yes
GO:0055069 zinc ion homeostasis 0.8811 8 yes
GO:0055076 transition metal ion homeostasis 0.8811 8 yes
GO:0097553 calcium ion transmembrane import into cytosol 0.8811 7 yes
GO:0006882 cellular zinc ion homeostasis 0.8811 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in LCK_HUMAN
DOID:612 primary immunodeficiency disease 1.7621 3 yes
DOID:1289 neurodegenerative disease 1.7621 4 no
DOID:331 central nervous system disease 1.7621 3 no
DOID:0050686 organ system cancer 1.7621 3 no
DOID:0060038 specific developmental disorder 1.3216 3 no
DOID:0060307 autosomal dominant intellectual developmental disorder 1.3216 5 no
DOID:1059 intellectual disability 1.3216 4 no
DOID:0050700 cardiomyopathy 1.3216 4 no
DOID:0060036 intrinsic cardiomyopathy 1.3216 5 no
DOID:114 heart disease 1.3216 3 no
DOID:0111962 combined immunodeficiency 0.8811 4 yes
DOID:627 severe combined immunodeficiency 0.8811 5 yes
DOID:3490 Noonan syndrome 0.8811 3 no
DOID:231 motor neuron disease 0.8811 5 no
DOID:193 reproductive organ cancer 0.8811 4 no
DOID:12930 dilated cardiomyopathy 0.8811 6 no
DOID:0111937 immunodeficiency 22 0.8811 6 yes
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PTCA_HUMAN [view interactions] Low throughput no no
PTPRC_HUMAN [view interactions] Low throughput no no
KHDR1_HUMAN [view interactions] Low throughput no yes
SKAP2_HUMAN [view interactions] Low throughput no no
FYB1_HUMAN [view interactions] Low throughput no no
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
CD3Z_HUMAN [view interactions] Low throughput no no
CD2_HUMAN [view interactions] Low throughput no no
P85A_HUMAN [view interactions] Low throughput no yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
BCAR1_HUMAN [view interactions] Low throughput no yes
PTN22_HUMAN [view interactions] Low throughput no yes
WASP_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
VAV_HUMAN [view interactions] Low throughput no no
3BP2_HUMAN [view interactions] Low throughput no yes
CD3E_HUMAN [view interactions] Low throughput no no
EGFR_HUMAN [view interactions] Low throughput no no
HAVR2_HUMAN [view interactions] Low throughput no no
THMS1_HUMAN [view interactions] Low throughput no no
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
HCLS1_HUMAN [view interactions] Low throughput no no
LAT_HUMAN [view interactions] Low throughput no no
STK11_HUMAN [view interactions] Low throughput no yes
SLAF6_HUMAN [view interactions] Low throughput no no
TNR6_HUMAN [view interactions] Low throughput no no
LCK_HUMAN [view entry] [view interactions] Low throughput yes no
WASL_HUMAN [view entry] [view interactions] Low throughput yes yes
CDC42_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN6_HUMAN [view interactions] Low throughput no no
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
DOK2_HUMAN [view interactions] Low throughput no no
MED25_HUMAN [view interactions] Low throughput no yes
CD44_HUMAN [view interactions] Low throughput no yes
KIT_HUMAN [view interactions] Low throughput no no
UBE3A_HUMAN [view interactions] Low throughput no yes
SOCS6_HUMAN [view interactions] Low throughput no yes
AJUBA_HUMAN [view interactions] Low throughput no yes
U119A_HUMAN [view interactions] Low throughput no no
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
NOTC1_HUMAN [view interactions] Low throughput no yes
FAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
PAXI_HUMAN [view interactions] Low throughput no yes
SH2B3_HUMAN [view interactions] Low throughput no yes
CD20_HUMAN [view interactions] Low throughput no no
CASL_HUMAN [view interactions] Low throughput no yes
CD48_HUMAN [view interactions] Low throughput no no
CD38_HUMAN [view interactions] Low throughput no no
CTLA4_HUMAN [view interactions] Low throughput no no
TRPV4_HUMAN [view interactions] Low throughput no yes
SIT1_HUMAN [view interactions] Low throughput no no
THY1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
CYLD_HUMAN [view entry] [view interactions] Low throughput yes yes
SKAP1_HUMAN [view interactions] Low throughput no no
CBLB_HUMAN [view interactions] Low throughput no yes
CD5_HUMAN [view interactions] Low throughput no no
IL2RB_HUMAN [view interactions] Low throughput no no
SOCS1_HUMAN [view interactions] Low throughput no yes
SOCS2_HUMAN [view interactions] Low throughput no yes
SOCS3_HUMAN [view interactions] Low throughput no yes
CISH_HUMAN [view interactions] Low throughput no yes
1433T_HUMAN [view entry] [view interactions] Low throughput yes yes
BAG6_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRF_HUMAN [view entry] [view interactions] Low throughput yes yes
FCG3A_HUMAN [view interactions] Low throughput no no
RHOH_HUMAN [view interactions] Low throughput no yes
TNFL6_HUMAN [view interactions] Low throughput no yes
SQSTM_HUMAN [view interactions] Low throughput no yes
SMAD2_HUMAN [view interactions] Low throughput no yes
SMAD3_HUMAN [view interactions] Low throughput no yes
CDC45_HUMAN [view interactions] Low throughput no no
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
ADA10_HUMAN [view entry] [view interactions] Low throughput yes yes
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
ADA15_HUMAN [view interactions] Low throughput no yes
PECA1_HUMAN [view interactions] Low throughput no no
CD4_HUMAN [view interactions] Low throughput no no
RASA1_HUMAN [view interactions] Low throughput no yes
CD8A_HUMAN [view interactions] Low throughput no no
SH22A_HUMAN [view interactions] Low throughput no no
UFO_HUMAN [view interactions] Low throughput no no
SH21A_HUMAN [view interactions] Low throughput no no
F174A_HUMAN [view interactions] Low throughput no yes
KSYK_HUMAN [view interactions] Low throughput no no
SOS1_HUMAN [view entry] [view interactions] Low throughput yes yes
MED28_HUMAN [view interactions] Low throughput no yes
CSK_HUMAN [view interactions] Low throughput no yes
CBL_HUMAN [view interactions] Low throughput no yes
G3BP1_HUMAN [view interactions] Low throughput no yes
BCL3_HUMAN [view interactions] Low throughput no yes
ZAP70_HUMAN [view interactions] Low throughput no no
LCP2_HUMAN [view interactions] Low throughput no yes
KPCT_HUMAN [view interactions] Low throughput no no
NF1_HUMAN [view entry] [view interactions] High throughput yes no
DIP2A_HUMAN [view interactions] High throughput no no
EF1B_HUMAN [view entry] [view interactions] High throughput yes yes
DIP2B_HUMAN [view entry] [view interactions] High throughput yes yes
SYVC_HUMAN [view interactions] High throughput no yes
DLG5_HUMAN [view entry] [view interactions] High throughput yes no
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
METK2_HUMAN [view interactions] High throughput no no
DNJC7_HUMAN [view interactions] High throughput no yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
DRG1_HUMAN [view interactions] High throughput no yes
SYIC_HUMAN [view interactions] High throughput no yes
DSC2_HUMAN [view interactions] High throughput no no
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
DSG2_HUMAN [view interactions] High throughput no no
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
DYST_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
DTNA_HUMAN [view entry] [view interactions] High throughput yes yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
EDRF1_HUMAN [view interactions] High throughput no no
BMX_HUMAN [view interactions] High throughput no no
EFNB2_HUMAN [view entry] [view interactions] High throughput yes yes
SYRC_HUMAN [view interactions] High throughput no yes
EFR3A_HUMAN [view entry] [view interactions] High throughput yes yes
IF4A1_HUMAN [view interactions] High throughput no no
EFR3B_HUMAN [view entry] [view interactions] High throughput yes no
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
E41L1_HUMAN [view entry] [view interactions] High throughput yes yes
RBM3_HUMAN [view interactions] High throughput no no
E41L5_HUMAN [view interactions] High throughput no no
PTPS_HUMAN [view interactions] High throughput no yes
EPHA2_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
ERBIN_HUMAN [view entry] [view interactions] High throughput yes yes
RL22L_HUMAN [view interactions] High throughput no no
ETFA_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC3_HUMAN [view entry] [view interactions] High throughput yes no
GHC1_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC5_HUMAN [view entry] [view interactions] High throughput yes yes
GHC2_HUMAN [view entry] [view interactions] High throughput yes no
NIBA2_HUMAN [view interactions] High throughput no no
QCR8_HUMAN [view interactions] High throughput no yes
F1711_HUMAN [view entry] [view interactions] High throughput yes yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
F1712_HUMAN [view interactions] High throughput no no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
F171B_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
FARP1_HUMAN [view entry] [view interactions] High throughput yes no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
FGD1_HUMAN [view interactions] High throughput no no
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP4_HUMAN [view entry] [view interactions] High throughput yes yes
XRCC5_HUMAN [view interactions] High throughput no yes
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
FMN2_HUMAN [view entry] [view interactions] High throughput yes no
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
FRS2_HUMAN [view interactions] High throughput no no
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
GCC2_HUMAN [view interactions] High throughput no yes
RMXL1_HUMAN [view interactions] High throughput no yes
GLMN_HUMAN [view interactions] High throughput no no
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
LAP2A_HUMAN [view interactions] High throughput no yes
GOGA3_HUMAN [view interactions] High throughput no yes
RAN_HUMAN [view entry] [view interactions] High throughput yes no
GOGA4_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
GOGB1_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
GRIN1_HUMAN [view entry] [view interactions] High throughput yes yes
NOLC1_HUMAN [view interactions] High throughput no yes
GRIN3_HUMAN [view interactions] High throughput no yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
IRS4_HUMAN [view interactions] High throughput no no
SAFB1_HUMAN [view interactions] High throughput no yes
KALRN_HUMAN [view entry] [view interactions] High throughput yes yes
RP9_HUMAN [view interactions] High throughput no yes
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1M_HUMAN [view interactions] High throughput no yes
K1522_HUMAN [view interactions] High throughput no yes
H2B1D_HUMAN [view interactions] High throughput no yes
K1549_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1C_HUMAN [view interactions] High throughput no yes
K1671_HUMAN [view interactions] High throughput no yes
H2B2F_HUMAN [view interactions] High throughput no yes
KDIS_HUMAN [view interactions] High throughput no yes
H2B1H_HUMAN [view interactions] High throughput no yes
KI16B_HUMAN [view interactions] High throughput no yes
H2B1N_HUMAN [view interactions] High throughput no yes
L2GL1_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1L_HUMAN [view interactions] High throughput no yes
LMTK2_HUMAN [view entry] [view interactions] High throughput yes yes
CDCP1_HUMAN [view interactions] High throughput no yes
LSR_HUMAN [view interactions] High throughput no yes
MACF1_HUMAN [view entry] [view interactions] High throughput yes yes
MD2L2_HUMAN [view interactions] High throughput no yes
KPCE_HUMAN [view entry] [view interactions] High throughput yes yes
M3K21_HUMAN [view interactions] High throughput no yes
M4K4_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
MARK2_HUMAN [view entry] [view interactions] High throughput yes yes
MARK3_HUMAN [view interactions] High throughput no yes
MINK1_HUMAN [view entry] [view interactions] High throughput yes yes
MPP7_HUMAN [view entry] [view interactions] High throughput yes no
MYO1B_HUMAN [view entry] [view interactions] High throughput yes no
MYO1C_HUMAN [view entry] [view interactions] High throughput yes yes
MYO1D_HUMAN [view entry] [view interactions] High throughput yes yes
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
NAV1_HUMAN [view interactions] High throughput no yes
NCK5L_HUMAN [view interactions] High throughput no yes
NISCH_HUMAN [view interactions] High throughput no yes
CAPON_HUMAN [view entry] [view interactions] High throughput yes yes
NOTC2_HUMAN [view interactions] High throughput no yes
NUDC_HUMAN [view interactions] High throughput no yes
NUDC3_HUMAN [view interactions] High throughput no yes
NUMBL_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
PALM_HUMAN [view entry] [view interactions] High throughput yes yes
EHD4_HUMAN [view entry] [view interactions] High throughput yes no
PALM2_HUMAN [view entry] [view interactions] High throughput yes no
PGM1_HUMAN [view interactions] High throughput no no
PARD3_HUMAN [view interactions] High throughput no yes
PRP4B_HUMAN [view interactions] High throughput no yes
PEAK1_HUMAN [view interactions] High throughput no yes
AP3M1_HUMAN [view interactions] High throughput no yes
PHAR4_HUMAN [view interactions] High throughput no yes
NUMB_HUMAN [view entry] [view interactions] High throughput yes yes
PHLB3_HUMAN [view interactions] High throughput no yes
LIPB1_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
P85B_HUMAN [view interactions] High throughput no yes
UAP1L_HUMAN [view interactions] High throughput no yes
PKN3_HUMAN [view interactions] High throughput no yes
RM45_HUMAN [view interactions] High throughput no no
PKP2_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKP4_HUMAN [view entry] [view interactions] High throughput yes yes
LACB2_HUMAN [view interactions] High throughput no yes
PLCH1_HUMAN [view interactions] High throughput no no
TNS2_HUMAN [view interactions] High throughput no no
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
API5_HUMAN [view interactions] High throughput no no
PKHA6_HUMAN [view entry] [view interactions] High throughput yes no
MA1A2_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
LIPA1_HUMAN [view entry] [view interactions] High throughput yes yes
XRN1_HUMAN [view interactions] High throughput no yes
PPID_HUMAN [view entry] [view interactions] High throughput yes yes
BLK_HUMAN [view interactions] High throughput no no
ASPP1_HUMAN [view interactions] High throughput no yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
PSD3_HUMAN [view entry] [view interactions] High throughput yes yes
HCK_HUMAN [view entry] [view interactions] High throughput yes no
PTN13_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] High throughput yes no
PTN14_HUMAN [view interactions] High throughput no yes
NGAP_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
PHAG1_HUMAN [view interactions] High throughput no yes
ROR2_HUMAN [view entry] [view interactions] High throughput yes yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
STAT3_HUMAN [view entry] [view interactions] High throughput yes yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
SCRIB_HUMAN [view entry] [view interactions] High throughput yes no
S12A2_HUMAN [view entry] [view interactions] High throughput yes yes
ZNT6_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
SNP23_HUMAN [view entry] [view interactions] High throughput yes no
SNTB2_HUMAN [view entry] [view interactions] High throughput yes no
SPTN1_HUMAN [view entry] [view interactions] High throughput yes yes
SPTB2_HUMAN [view entry] [view interactions] High throughput yes yes
SPTN2_HUMAN [view entry] [view interactions] High throughput yes yes
F10A1_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
RIN3_HUMAN [view interactions] High throughput no yes
SGT1_HUMAN [view interactions] High throughput no no
CDKAL_HUMAN [view interactions] High throughput no no
TANC1_HUMAN [view entry] [view interactions] High throughput yes yes
LZTS2_HUMAN [view interactions] High throughput no no
SYTM_HUMAN [view interactions] High throughput no yes
GATA3_HUMAN [view interactions] High throughput no no
TOM22_HUMAN [view interactions] High throughput no yes
TOM34_HUMAN [view entry] [view interactions] High throughput yes yes
NEMO_HUMAN [view interactions] High throughput no yes
TRIPB_HUMAN [view interactions] High throughput no yes
FLT3_HUMAN [view interactions] High throughput no no
TTC1_HUMAN [view interactions] High throughput no yes
TTC4_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
TTC9C_HUMAN [view interactions] High throughput no yes
GAB1_HUMAN [view interactions] High throughput no yes
UN45A_HUMAN [view interactions] High throughput no yes
UBP54_HUMAN [view interactions] High throughput no yes
MET_HUMAN [view interactions] High throughput no yes
US6NL_HUMAN [view interactions] High throughput no yes
PTPRM_HUMAN [view interactions] High throughput no yes
UTRN_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRK_HUMAN [view interactions] High throughput no no
VANG1_HUMAN [view interactions] High throughput no no
PTPRG_HUMAN [view interactions] High throughput no no
WDR6_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRZ_HUMAN [view entry] [view interactions] High throughput yes yes
XPR1_HUMAN [view interactions] High throughput no yes
PTPRB_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRJ_HUMAN [view interactions] High throughput no yes
SEPT7_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRO_HUMAN [view entry] [view interactions] High throughput yes no
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
PTN12_HUMAN [view interactions] High throughput no yes
AHNK2_HUMAN [view interactions] High throughput no yes
UHRF2_HUMAN [view interactions] High throughput no no
AMOT_HUMAN [view interactions] High throughput no no
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
ANK3_HUMAN [view entry] [view interactions] High throughput yes yes
DAF_HUMAN [view interactions] High throughput no no
RHG21_HUMAN [view entry] [view interactions] High throughput yes yes
AURKB_HUMAN [view interactions] High throughput no yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
CARL1_HUMAN [view interactions] High throughput no yes
STAP1_HUMAN [view interactions] High throughput no no
CEP55_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
CHRD1_HUMAN [view interactions] High throughput no yes
FAK1_HUMAN [view entry] [view interactions] High throughput yes yes
CRBG3_HUMAN [view interactions] High throughput no no
ASB9_HUMAN [view interactions] High throughput no no
CSTFT_HUMAN [view interactions] High throughput no yes
TRI35_HUMAN [view interactions] High throughput no yes
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
UBAP2_HUMAN [view interactions] High throughput no yes
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
CTDS1_HUMAN [view interactions] High throughput no no
DEST_HUMAN [view entry] [view interactions] High throughput yes yes
C1QT2_HUMAN [view interactions] High throughput no yes
EGLN1_HUMAN [view entry] [view interactions] High throughput yes yes
IKBD_HUMAN [view interactions] High throughput no no
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
F166B_HUMAN [view interactions] High throughput no no
EXOC4_HUMAN [view entry] [view interactions] High throughput yes yes
FERM2_HUMAN [view interactions] High throughput no yes
GOGA5_HUMAN [view interactions] High throughput no yes
JPH1_HUMAN [view interactions] High throughput no no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
MPRIP_HUMAN [view entry] [view interactions] High throughput yes yes
MYO5A_HUMAN [view entry] [view interactions] High throughput yes yes
OCRL_HUMAN [view interactions] High throughput no yes
AKAP2_HUMAN [view interactions] High throughput no no
PFKAL_HUMAN [view entry] [view interactions] High throughput yes yes
PFKAM_HUMAN [view entry] [view interactions] High throughput yes yes
PFKAP_HUMAN [view entry] [view interactions] High throughput yes yes
RFIP1_HUMAN [view interactions] High throughput no yes
RAI14_HUMAN [view interactions] High throughput no yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
SI1L2_HUMAN [view interactions] High throughput no yes
4F2_HUMAN [view entry] [view interactions] High throughput yes no
SNX6_HUMAN [view entry] [view interactions] High throughput yes no
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
SYNJ1_HUMAN [view entry] [view interactions] High throughput yes yes
TB182_HUMAN [view interactions] High throughput no yes
TRIO_HUMAN [view entry] [view interactions] High throughput yes yes
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
SYYC_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
TLE5_HUMAN [view interactions] High throughput no no
STIM1_HUMAN [view interactions] High throughput no yes
MEN1_HUMAN [view interactions] High throughput no yes
SPAST_HUMAN [view interactions] High throughput no yes
CAMP2_HUMAN [view interactions] High throughput no yes
NELFD_HUMAN [view interactions] High throughput no yes
ESCO1_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
EP300_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
MK12_HUMAN [view interactions] High throughput no no
P3C2B_HUMAN [view interactions] High throughput no no
AMHR2_HUMAN [view interactions] High throughput no no
M3K8_HUMAN [view interactions] High throughput no yes
ITB7_HUMAN [view interactions] High throughput no no
KCC2G_HUMAN [view entry] [view interactions] High throughput yes yes
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
CRBB1_HUMAN [view interactions] High throughput no no
MASP2_HUMAN [view interactions] High throughput no no
PTK6_HUMAN [view interactions] High throughput no yes
NOS2_HUMAN [view interactions] High throughput no yes
LT4R1_HUMAN [view interactions] High throughput no yes
EPHB4_HUMAN [view interactions] High throughput no yes
IFNL1_HUMAN [view interactions] High throughput no no
IL21R_HUMAN [view interactions] High throughput no no
IL6RA_HUMAN [view interactions] High throughput no no
RHG17_HUMAN [view interactions] High throughput no no
TRAT1_HUMAN [view interactions] High throughput no no
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
ERBB3_HUMAN [view interactions] High throughput no yes
ERBB4_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
MBP_HUMAN [view entry] [view interactions] High throughput yes no
MTR1B_HUMAN [view interactions] High throughput no yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
GCP60_HUMAN [view interactions] High throughput no yes
AIP_HUMAN [view entry] [view interactions] High throughput yes yes
ANR26_HUMAN [view interactions] High throughput no yes
AP2A1_HUMAN [view entry] [view interactions] High throughput yes yes
AP3D1_HUMAN [view entry] [view interactions] High throughput yes no
AP3S1_HUMAN [view entry] [view interactions] High throughput yes no
ARAP2_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
RHG32_HUMAN [view entry] [view interactions] High throughput yes yes
ZBED8_HUMAN [view interactions] High throughput no yes
AR13B_HUMAN [view interactions] High throughput no yes
CDK13_HUMAN [view interactions] High throughput no no
AT2B1_HUMAN [view entry] [view interactions] High throughput yes yes
HPS5_HUMAN [view interactions] High throughput no yes
BASP1_HUMAN [view entry] [view interactions] High throughput yes yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
CABL1_HUMAN [view interactions] High throughput no no
YES_HUMAN [view entry] [view interactions] High throughput yes yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
PHF5A_HUMAN [view interactions] High throughput no yes
CSKI2_HUMAN [view interactions] High throughput no yes
NSE2_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
C2CD5_HUMAN [view interactions] High throughput no yes
GRDN_HUMAN [view interactions] High throughput no no
ATP5I_HUMAN [view interactions] High throughput no yes
MRCKA_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
MRCKB_HUMAN [view entry] [view interactions] High throughput yes yes
MECOM_HUMAN [view interactions] High throughput no yes
CDCA3_HUMAN [view interactions] High throughput no no
E2F7_HUMAN [view interactions] High throughput no no
CDK3_HUMAN [view interactions] High throughput no no
CDK1_HUMAN [view interactions] High throughput no no
CEP89_HUMAN [view interactions] High throughput no no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
CNO10_HUMAN [view interactions] High throughput no yes
H90B3_HUMAN [view interactions] High throughput no no
CN37_HUMAN [view entry] [view interactions] High throughput yes no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
COBL1_HUMAN [view interactions] High throughput no yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
COG1_HUMAN [view interactions] High throughput no yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
DDX54_HUMAN [view interactions] High throughput no yes
CAN2_HUMAN [view interactions] Computational no no
SLAF1_HUMAN [view interactions] Computational no no
CRK_HUMAN [view entry] [view interactions] Computational yes no
SYUA_HUMAN [view entry] [view interactions] Computational yes no
DRB1_HUMAN [view interactions] Computational no no
PLCG1_HUMAN [view entry] [view interactions] Computational yes yes
GBG2_HUMAN [view entry] [view interactions] Computational yes yes
CD8B_HUMAN [view interactions] Computational no no
RHOA_HUMAN [view entry] [view interactions] Computational yes yes
CD3D_HUMAN [view interactions] Computational no no
SDF1_HUMAN [view interactions] Computational no no
2A5A_HUMAN [view interactions] Computational no yes
AFAD_HUMAN [view interactions] Computational no yes
I12R2_HUMAN [view interactions] Computational no no
MK09_HUMAN [view interactions] Computational no yes
GRB7_HUMAN [view interactions] Computational no no
RPGF1_HUMAN [view interactions] Computational no yes
IL2RG_HUMAN [view interactions] Computational no no
MP2K1_HUMAN [view entry] [view interactions] Computational yes yes
IKZF3_HUMAN [view interactions] Computational no no
CD80_HUMAN [view interactions] Computational no no
EFNA5_HUMAN [view interactions] Computational no yes
TRAF2_HUMAN [view interactions] Computational no yes
PAK1_HUMAN [view entry] [view interactions] Computational yes yes
FGR_HUMAN [view interactions] Computational no no
NGEF_HUMAN [view entry] [view interactions] Computational yes yes
VAV2_HUMAN [view entry] [view interactions] Computational yes yes
TRPV6_HUMAN [view interactions] Computational no no
DOCK1_HUMAN [view entry] [view interactions] Computational yes yes
PLCG2_HUMAN [view interactions] Computational no yes
STA5A_HUMAN [view interactions] Computational no no
RASK_HUMAN [view entry] [view interactions] Computational yes no
GIT2_HUMAN [view interactions] Computational no yes
IL2_HUMAN [view interactions] Computational no no
MK11_HUMAN [view interactions] Computational no yes
DRA_HUMAN [view interactions] Computational no no
EPHB2_HUMAN [view entry] [view interactions] Computational yes yes
ASM_HUMAN [view interactions] Computational no no
HLAA_HUMAN [view interactions] Computational no no
TNR9_HUMAN [view interactions] Computational no no
SH3G1_HUMAN [view entry] [view interactions] Computational yes no
M4K1_HUMAN [view interactions] Computational no no
ITK_HUMAN [view interactions] Computational no no
EPHA1_HUMAN [view interactions] Computational no yes
IRS1_HUMAN [view entry] [view interactions] Computational yes yes
EPHB1_HUMAN [view interactions] Computational no no
JAK1_HUMAN [view interactions] Computational no yes
AKT1_HUMAN [view entry] [view interactions] Computational yes yes
I12R1_HUMAN [view interactions] Computational no no
NCK2_HUMAN [view entry] [view interactions] Computational yes yes
IRS2_HUMAN [view interactions] Computational no yes
PTN21_HUMAN [view interactions] Computational no yes
JAK3_HUMAN [view interactions] Computational no no
DAPP1_HUMAN [view interactions] Computational no yes
TYK2_HUMAN [view interactions] Computational no no
EPHA7_HUMAN [view entry] [view interactions] Computational yes no
CEGT_HUMAN [view interactions] Computational no yes
SLAP2_HUMAN [view interactions] Computational no no
GRAP2_HUMAN [view interactions] Computational no no
MK03_HUMAN [view entry] [view interactions] Computational yes yes
ITAV_HUMAN [view interactions] Computational no yes
SMS1_HUMAN [view interactions] Computational no yes
GBB1_HUMAN [view entry] [view interactions] Computational yes yes
EPHA4_HUMAN [view entry] [view interactions] Computational yes yes
KPCZ_HUMAN [view entry] [view interactions] Computational yes yes
ELMO1_HUMAN [view interactions] Computational no no
PGFRB_HUMAN [view interactions] Computational no yes
DOK1_HUMAN [view interactions] Computational no yes
2AAB_HUMAN [view interactions] Computational no yes
TYOBP_HUMAN [view interactions] Computational no no
IL12B_HUMAN [view interactions] Computational no yes
TRAF6_HUMAN [view interactions] Computational no yes
GNAZ_HUMAN [view entry] [view interactions] Computational yes yes
EGF_HUMAN [view interactions] Computational no no
MK08_HUMAN [view interactions] Computational no yes
SLAP1_HUMAN [view interactions] Computational no yes
PP2AB_HUMAN [view interactions] Computational no yes
2A5B_HUMAN [view interactions] Computational no yes
TDGF1_HUMAN [view interactions] Computational no no
PDGFB_HUMAN [view interactions] Computational no yes
IL12A_HUMAN [view interactions] Computational no no
IL2RA_HUMAN [view interactions] Computational no no
GAB2_HUMAN [view interactions] Computational no yes
JAK2_HUMAN [view entry] [view interactions] Computational yes yes
2A5D_HUMAN [view entry] [view interactions] Computational yes yes
STAT1_HUMAN [view entry] [view interactions] Computational yes no
CXCR4_HUMAN [view interactions] Computational no no
RRAS_HUMAN [view interactions] Computational no yes
RASH_HUMAN [view entry] [view interactions] Computational yes no
ABL1_HUMAN [view entry] [view interactions] Computational yes yes
TF65_HUMAN [view entry] [view interactions] Computational yes yes
NFKB1_HUMAN [view interactions] Computational no yes
STAM2_HUMAN [view interactions] Computational no yes
EFNB1_HUMAN [view interactions] Computational no yes
PTN11_HUMAN [view entry] [view interactions] Computational yes yes
RASN_HUMAN [view entry] [view interactions] Computational yes no
GNAO_HUMAN [view entry] [view interactions] Computational yes yes
CD86_HUMAN [view interactions] Computational no yes
RHG35_HUMAN [view interactions] Computational no yes
GNAI3_HUMAN [view entry] [view interactions] Computational yes yes
CD28_HUMAN [view interactions] Computational no no
EPHA3_HUMAN [view interactions] Computational no yes
STAM1_HUMAN [view interactions] Computational no yes
NCK1_HUMAN [view interactions] Computational no yes
ITB5_HUMAN [view interactions] Computational no yes
GNAI1_HUMAN [view entry] [view interactions] Computational yes yes
SHC1_HUMAN [view entry] [view interactions] Computational yes yes
ITA2B_HUMAN [view interactions] Computational no no
MK14_HUMAN [view interactions] Computational no yes
IKBA_HUMAN [view interactions] Computational no yes
S1PR1_HUMAN [view interactions] Computational no no
RAC1_HUMAN [view entry] [view interactions] Computational yes no
RGS1_HUMAN [view interactions] Computational no yes
JIP3_HUMAN [view entry] [view interactions] Computational yes yes
2AAA_HUMAN [view entry] [view interactions] Computational yes no
BTK_HUMAN [view interactions] Computational no no
2A5G_HUMAN [view interactions] Computational no yes
VINC_HUMAN [view entry] [view interactions] Computational yes no
GPC1_HUMAN [view entry] [view interactions] Computational yes no
GNAI2_HUMAN [view entry] [view interactions] Computational yes yes
MP2K2_HUMAN [view entry] [view interactions] Computational yes yes
2A5E_HUMAN [view interactions] Computational no yes
EFNA1_HUMAN [view interactions] Computational no no
ARHG7_HUMAN [view entry] [view interactions] Computational yes yes
BLNK_HUMAN [view entry] [view interactions] Computational yes no
ACTN1_HUMAN [view entry] [view interactions] Computational yes yes
PP2AA_HUMAN [view entry] [view interactions] Computational yes yes
DBNL_HUMAN [view entry] [view interactions] Computational yes yes
CD3G_HUMAN [view interactions] Computational no no
KPCD_HUMAN [view entry] [view interactions] Computational yes yes
STA5B_HUMAN [view interactions] Computational no yes
KLRB1_HUMAN [view interactions] Computational no yes