Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

STAT3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed). Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes (PubMed). Activated by IL31 through IL31RA (PubMed). Acts as a regulator of inflammatory response by regulating differentiation of naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells (Treg): deacetylation and oxidation of lysine residues by LOXL3, leads to disrupt STAT3 dimerization and inhibit its transcription activity (PubMed). Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed). Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation . May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed). Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity (PubMed). Plays a crucial role in basal beta cell functions, such as regulation of insulin secretion . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
382 Arg Leu Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
382 Arg Gln Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
382 Arg Trp Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
384 Phe Leu Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
384 Phe Ser Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
389 Thr Ile Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
423 Arg Gln Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
437 His Tyr Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
611 Ser Asn Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
621 Phe Val Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
622 Thr Ile Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
637 Val Leu Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
637 Val Met Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
657 Tyr Cys Hyper-IgErecurrentinfectionsyndrome1,autosomaldominant(HIES1) -
392 Lys Arg Autoimmunedisease,multisystem,infantile-onset,1(ADMIO1) -
646 Asn Lys Autoimmunedisease,multisystem,infantile-onset,1(ADMIO1) -
658 Lys Asn Autoimmunedisease,multisystem,infantile-onset,1(ADMIO1) -
716 Thr Met Autoimmunedisease,multisystem,infantile-onset,1(ADMIO1) -
330 Pro Ser Autoimmunedisease,multisystem,infantile-onset,1(ADMIO1) -

Linear motifs

ELM instance Name Type Start End Partner
ELMI002020 DOC_WW_Pin1_4 DOC 724 729 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in STAT3_HUMAN
GO:0017076 purine nucleotide binding 42.0000 4 no
GO:0032555 purine ribonucleotide binding 42.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 42.0000 4 no
GO:0005524 ATP binding 40.0000 5 no
GO:0030554 adenyl nucleotide binding 40.0000 5 no
GO:0032559 adenyl ribonucleotide binding 40.0000 5 no
GO:0016301 kinase activity 32.0000 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 30.0000 4 no
GO:0004712 protein serine/threonine/tyrosine kinase activity 29.0000 4 no
GO:0046872 metal ion binding 25.0000 4 no
GO:0003723 RNA binding 22.0000 4 yes
GO:0019900 kinase binding 22.0000 4 yes
GO:0019901 protein kinase binding 22.0000 5 yes
GO:0004713 protein tyrosine kinase activity 21.0000 4 no
GO:0042803 protein homodimerization activity 18.0000 4 yes
GO:0019902 phosphatase binding 12.0000 4 yes
GO:0140297 DNA-binding transcription factor binding 11.0000 4 yes
GO:0003677 DNA binding 10.0000 4 yes
GO:0019903 protein phosphatase binding 10.0000 5 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9.0000 5 yes
GO:0003690 double-stranded DNA binding 7.0000 5 yes
GO:0043565 sequence-specific DNA binding 7.0000 5 yes
GO:0000976 transcription cis-regulatory region binding 6.0000 5 yes
GO:0000987 cis-regulatory region sequence-specific DNA binding 6.0000 6 yes
GO:0001067 transcription regulatory region nucleic acid binding 6.0000 4 yes
GO:1990837 sequence-specific double-stranded DNA binding 6.0000 6 yes
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding 5.0000 6 yes
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding 5.0000 7 yes
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 4.0000 4 yes
GO:0070878 primary miRNA binding 2.0000 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in STAT3_HUMAN
GO:0048522 positive regulation of cellular process 68.0000 4 yes
GO:0031323 regulation of cellular metabolic process 66.0000 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 63.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 62.0000 4 yes
GO:0080090 regulation of primary metabolic process 62.0000 4 yes
GO:0048523 negative regulation of cellular process 59.0000 4 yes
GO:0010646 regulation of cell communication 57.0000 4 yes
GO:0010468 regulation of gene expression 55.0000 5 yes
GO:0009966 regulation of signal transduction 54.0000 4 yes
GO:0009893 positive regulation of metabolic process 50.0000 4 yes
GO:0009889 regulation of biosynthetic process 48.0000 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 48.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 48.0000 5 yes
GO:0051128 regulation of cellular component organization 47.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 47.0000 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 45.0000 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 44.0000 5 yes
GO:0051246 regulation of protein metabolic process 44.0000 5 yes
GO:0031325 positive regulation of cellular metabolic process 44.0000 5 yes
GO:1902531 regulation of intracellular signal transduction 43.0000 5 no
GO:0048584 positive regulation of response to stimulus 42.0000 4 yes
GO:0051252 regulation of RNA metabolic process 40.0000 5 yes
GO:0023056 positive regulation of signaling 40.0000 4 yes
GO:0071310 cellular response to organic substance 39.0000 4 yes
GO:0010647 positive regulation of cell communication 39.0000 5 yes
GO:0009892 negative regulation of metabolic process 37.0000 4 yes
GO:0006796 phosphate-containing compound metabolic process 36.0000 4 yes
GO:0051247 positive regulation of protein metabolic process 35.0000 6 yes
GO:0036211 protein modification process 35.0000 4 no
GO:0043412 macromolecule modification 35.0000 4 no
GO:0009967 positive regulation of signal transduction 35.0000 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 34.0000 7 yes
GO:2001141 regulation of RNA biosynthetic process 34.0000 6 yes
GO:0051049 regulation of transport 34.0000 4 no
GO:0010941 regulation of cell death 34.0000 4 no
GO:0006355 regulation of DNA-templated transcription 34.0000 6 yes
GO:0051174 regulation of phosphorus metabolic process 32.0000 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 32.0000 5 yes
GO:0019220 regulation of phosphate metabolic process 32.0000 6 yes
GO:0043067 regulation of programmed cell death 31.0000 5 no
GO:0031399 regulation of protein modification process 31.0000 6 no
GO:0080134 regulation of response to stress 31.0000 4 no
GO:0009891 positive regulation of biosynthetic process 31.0000 5 yes
GO:0016310 phosphorylation 31.0000 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 31.0000 6 yes
GO:0042325 regulation of phosphorylation 31.0000 7 yes
GO:0042981 regulation of apoptotic process 30.0000 6 no
GO:0033043 regulation of organelle organization 30.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 30.0000 5 yes
GO:0042127 regulation of cell population proliferation 30.0000 4 yes
GO:0043085 positive regulation of catalytic activity 30.0000 4 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 30.0000 6 yes
GO:0006996 organelle organization 29.0000 4 no
GO:0048585 negative regulation of response to stimulus 29.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 29.0000 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 29.0000 6 yes
GO:0010628 positive regulation of gene expression 29.0000 6 yes
GO:0045595 regulation of cell differentiation 29.0000 4 yes
GO:0022607 cellular component assembly 28.0000 4 no
GO:0051130 positive regulation of cellular component organization 28.0000 5 no
GO:0007167 enzyme-linked receptor protein signaling pathway 28.0000 4 yes
GO:1902533 positive regulation of intracellular signal transduction 28.0000 6 no
GO:0051172 negative regulation of nitrogen compound metabolic process 27.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 27.0000 4 yes
GO:0001932 regulation of protein phosphorylation 27.0000 7 no
GO:0010562 positive regulation of phosphorus metabolic process 27.0000 6 no
GO:0042327 positive regulation of phosphorylation 27.0000 8 no
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 27.0000 5 yes
GO:0045937 positive regulation of phosphate metabolic process 27.0000 7 no
GO:0060548 negative regulation of cell death 26.0000 5 no
GO:0006468 protein phosphorylation 26.0000 5 no
GO:0031401 positive regulation of protein modification process 26.0000 7 no
GO:0032101 regulation of response to external stimulus 26.0000 4 no
GO:0008104 protein localization 26.0000 4 yes
GO:0043408 regulation of MAPK cascade 26.0000 6 no
GO:0071702 organic substance transport 25.0000 4 yes
GO:2000026 regulation of multicellular organismal development 25.0000 4 yes
GO:2000145 regulation of cell motility 25.0000 4 yes
GO:0001934 positive regulation of protein phosphorylation 25.0000 8 no
GO:0051338 regulation of transferase activity 25.0000 4 no
GO:0009894 regulation of catabolic process 25.0000 4 yes
GO:0010243 response to organonitrogen compound 25.0000 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 25.0000 4 yes
GO:0033993 response to lipid 25.0000 4 yes
GO:0051094 positive regulation of developmental process 24.0000 4 yes
GO:0051254 positive regulation of RNA metabolic process 24.0000 6 yes
GO:0071705 nitrogen compound transport 24.0000 4 yes
GO:0010648 negative regulation of cell communication 24.0000 5 no
GO:0023057 negative regulation of signaling 24.0000 4 no
GO:0060341 regulation of cellular localization 24.0000 4 no
GO:0044087 regulation of cellular component biogenesis 24.0000 4 no
GO:0051336 regulation of hydrolase activity 23.0000 4 yes
GO:1902680 positive regulation of RNA biosynthetic process 23.0000 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 23.0000 8 yes
GO:0051241 negative regulation of multicellular organismal process 23.0000 4 no
GO:0009968 negative regulation of signal transduction 23.0000 5 no
GO:0030334 regulation of cell migration 23.0000 5 yes
GO:0045893 positive regulation of DNA-templated transcription 23.0000 7 yes
GO:0043066 negative regulation of apoptotic process 22.0000 7 no
GO:0043069 negative regulation of programmed cell death 22.0000 6 no
GO:0002684 positive regulation of immune system process 22.0000 4 no
GO:0051347 positive regulation of transferase activity 22.0000 5 no
GO:0008284 positive regulation of cell population proliferation 22.0000 5 yes
GO:0043549 regulation of kinase activity 21.0000 5 no
GO:0050776 regulation of immune response 21.0000 4 no
GO:0031344 regulation of cell projection organization 21.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.0000 6 no
GO:0018193 peptidyl-amino acid modification 21.0000 5 no
GO:0051493 regulation of cytoskeleton organization 21.0000 6 no
GO:0030155 regulation of cell adhesion 21.0000 4 no
GO:0015031 protein transport 21.0000 4 yes
GO:2000147 positive regulation of cell motility 20.0000 5 yes
GO:0006886 intracellular protein transport 20.0000 4 yes
GO:0014070 response to organic cyclic compound 20.0000 4 yes
GO:0030335 positive regulation of cell migration 20.0000 6 yes
GO:0031329 regulation of cellular catabolic process 20.0000 5 yes
GO:0040017 positive regulation of locomotion 20.0000 4 yes
GO:0051093 negative regulation of developmental process 18.0000 4 yes
GO:0001817 regulation of cytokine production 18.0000 4 yes
GO:0045597 positive regulation of cell differentiation 18.0000 5 yes
GO:0051345 positive regulation of hydrolase activity 17.0000 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 17.0000 7 yes
GO:0010629 negative regulation of gene expression 17.0000 6 yes
GO:0030162 regulation of proteolysis 16.0000 6 yes
GO:0051726 regulation of cell cycle 15.0000 4 yes
GO:1901652 response to peptide 15.0000 4 yes
GO:0009890 negative regulation of biosynthetic process 15.0000 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 15.0000 6 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 15.0000 8 yes
GO:0051253 negative regulation of RNA metabolic process 14.0000 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 14.0000 6 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 14.0000 6 yes
GO:0048878 chemical homeostasis 13.0000 4 yes
GO:0052547 regulation of peptidase activity 13.0000 5 yes
GO:0052548 regulation of endopeptidase activity 13.0000 6 yes
GO:0008285 negative regulation of cell population proliferation 13.0000 5 yes
GO:0009895 negative regulation of catabolic process 13.0000 5 yes
GO:0045596 negative regulation of cell differentiation 13.0000 5 yes
GO:1902679 negative regulation of RNA biosynthetic process 12.0000 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 12.0000 8 yes
GO:0001819 positive regulation of cytokine production 12.0000 5 yes
GO:0044271 cellular nitrogen compound biosynthetic process 12.0000 4 yes
GO:0045862 positive regulation of proteolysis 12.0000 7 yes
GO:0045892 negative regulation of DNA-templated transcription 12.0000 7 yes
GO:1901342 regulation of vasculature development 11.0000 5 yes
GO:0010506 regulation of autophagy 11.0000 6 yes
GO:0033365 protein localization to organelle 11.0000 5 yes
GO:0043434 response to peptide hormone 11.0000 4 yes
GO:0045765 regulation of angiogenesis 11.0000 5 yes
GO:0050678 regulation of epithelial cell proliferation 10.0000 5 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 10.0000 4 yes
GO:0072594 establishment of protein localization to organelle 10.0000 4 yes
GO:0010001 glial cell differentiation 10.0000 4 yes
GO:0019221 cytokine-mediated signaling pathway 10.0000 4 yes
GO:0031330 negative regulation of cellular catabolic process 10.0000 6 yes
GO:0032870 cellular response to hormone stimulus 10.0000 4 yes
GO:0048638 regulation of developmental growth 9.0000 4 yes
GO:1903706 regulation of hemopoiesis 9.0000 4 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 9.0000 8 yes
GO:0006954 inflammatory response 9.0000 4 yes
GO:0009059 macromolecule biosynthetic process 9.0000 4 yes
GO:0030182 neuron differentiation 9.0000 4 yes
GO:0040013 negative regulation of locomotion 9.0000 4 yes
GO:0090304 nucleic acid metabolic process 8.0000 4 yes
GO:1901362 organic cyclic compound biosynthetic process 8.0000 4 yes
GO:2000146 negative regulation of cell motility 8.0000 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 8.0000 6 yes
GO:0010950 positive regulation of endopeptidase activity 8.0000 7 yes
GO:0010952 positive regulation of peptidase activity 8.0000 6 yes
GO:0018130 heterocycle biosynthetic process 8.0000 4 yes
GO:0030336 negative regulation of cell migration 8.0000 6 yes
GO:0045936 negative regulation of phosphate metabolic process 8.0000 7 yes
GO:0048708 astrocyte differentiation 7.0000 5 yes
GO:0050679 positive regulation of epithelial cell proliferation 7.0000 6 yes
GO:0001936 regulation of endothelial cell proliferation 7.0000 6 yes
GO:0019438 aromatic compound biosynthetic process 7.0000 4 yes
GO:0033500 carbohydrate homeostasis 7.0000 5 yes
GO:0042326 negative regulation of phosphorylation 7.0000 8 yes
GO:0042593 glucose homeostasis 7.0000 6 yes
GO:0045637 regulation of myeloid cell differentiation 7.0000 5 yes
GO:0051092 positive regulation of NF-kappaB transcription factor activity 6.0000 5 yes
GO:0010507 negative regulation of autophagy 6.0000 7 yes
GO:0016070 RNA metabolic process 6.0000 5 yes
GO:0032355 response to estradiol 6.0000 4 yes
GO:0034504 protein localization to nucleus 6.0000 6 yes
GO:0034654 nucleobase-containing compound biosynthetic process 6.0000 4 yes
GO:0051169 nuclear transport 5.0000 4 yes
GO:0051170 import into nucleus 5.0000 6 yes
GO:0060147 regulation of post-transcriptional gene silencing 5.0000 6 yes
GO:0060396 growth hormone receptor signaling pathway 5.0000 6 yes
GO:0060964 regulation of miRNA-mediated gene silencing 5.0000 8 yes
GO:0060966 regulation of gene silencing by RNA 5.0000 6 yes
GO:0062012 regulation of small molecule metabolic process 5.0000 4 yes
GO:1900368 regulation of post-transcriptional gene silencing by RNA 5.0000 7 yes
GO:1902893 regulation of miRNA transcription 5.0000 7 yes
GO:1902895 positive regulation of miRNA transcription 5.0000 8 yes
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5.0000 5 yes
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 5.0000 6 yes
GO:1904018 positive regulation of vasculature development 5.0000 5 yes
GO:2000628 regulation of miRNA metabolic process 5.0000 6 yes
GO:2000630 positive regulation of miRNA metabolic process 5.0000 7 yes
GO:0001938 positive regulation of endothelial cell proliferation 5.0000 7 yes
GO:0006109 regulation of carbohydrate metabolic process 5.0000 5 yes
GO:0006606 protein import into nucleus 5.0000 5 yes
GO:0006913 nucleocytoplasmic transport 5.0000 5 yes
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 5.0000 5 yes
GO:0007399 nervous system development 5.0000 4 yes
GO:0008593 regulation of Notch signaling pathway 5.0000 5 yes
GO:0010675 regulation of cellular carbohydrate metabolic process 5.0000 5 yes
GO:0032680 regulation of tumor necrosis factor production 5.0000 6 yes
GO:0032760 positive regulation of tumor necrosis factor production 5.0000 7 yes
GO:0040014 regulation of multicellular organism growth 5.0000 4 yes
GO:0043467 regulation of generation of precursor metabolites and energy 5.0000 5 yes
GO:0045766 positive regulation of angiogenesis 5.0000 6 yes
GO:0060148 positive regulation of post-transcriptional gene silencing 4.0000 4 yes
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT 4.0000 7 yes
GO:0062014 negative regulation of small molecule metabolic process 4.0000 5 yes
GO:0070102 interleukin-6-mediated signaling pathway 4.0000 5 yes
GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 4.0000 6 yes
GO:0097659 nucleic acid-templated transcription 4.0000 6 yes
GO:0097696 receptor signaling pathway via STAT 4.0000 4 yes
GO:1900370 positive regulation of post-transcriptional gene silencing by RNA 4.0000 5 yes
GO:1903798 regulation of miRNA maturation 4.0000 7 yes
GO:2000637 positive regulation of miRNA-mediated gene silencing 4.0000 6 yes
GO:0006351 DNA-templated transcription 4.0000 7 yes
GO:0007179 transforming growth factor beta receptor signaling pathway 4.0000 6 yes
GO:0007259 receptor signaling pathway via JAK-STAT 4.0000 5 yes
GO:0032651 regulation of interleukin-1 beta production 4.0000 6 yes
GO:0032652 regulation of interleukin-1 production 4.0000 5 yes
GO:0032675 regulation of interleukin-6 production 4.0000 5 yes
GO:0032731 positive regulation of interleukin-1 beta production 4.0000 7 yes
GO:0032732 positive regulation of interleukin-1 production 4.0000 6 yes
GO:0032755 positive regulation of interleukin-6 production 4.0000 6 yes
GO:0032774 RNA biosynthetic process 4.0000 5 yes
GO:0045639 positive regulation of myeloid cell differentiation 4.0000 6 yes
GO:0045646 regulation of erythrocyte differentiation 4.0000 6 yes
GO:0050795 regulation of behavior 3.0000 4 yes
GO:0060149 negative regulation of post-transcriptional gene silencing 3.0000 4 yes
GO:0060965 negative regulation of miRNA-mediated gene silencing 3.0000 6 yes
GO:0060967 negative regulation of gene silencing by RNA 3.0000 4 yes
GO:1900369 negative regulation of post-transcriptional gene silencing by RNA 3.0000 5 yes
GO:1905562 regulation of vascular endothelial cell proliferation 3.0000 7 yes
GO:1905564 positive regulation of vascular endothelial cell proliferation 3.0000 8 yes
GO:2000736 regulation of stem cell differentiation 3.0000 5 yes
GO:0002295 T-helper cell lineage commitment 3.0000 7 yes
GO:0002360 T cell lineage commitment 3.0000 4 yes
GO:0002363 alpha-beta T cell lineage commitment 3.0000 5 yes
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.0000 4 yes
GO:0016071 mRNA metabolic process 3.0000 6 yes
GO:0032677 regulation of interleukin-8 production 3.0000 5 yes
GO:0032757 positive regulation of interleukin-8 production 3.0000 6 yes
GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 3.0000 5 yes
GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 3.0000 6 yes
GO:0045648 positive regulation of erythrocyte differentiation 3.0000 7 yes
GO:0045747 positive regulation of Notch signaling pathway 3.0000 6 yes
GO:0045980 negative regulation of nucleotide metabolic process 2.0000 6 yes
GO:0046530 photoreceptor cell differentiation 2.0000 5 yes
GO:0060019 radial glial cell differentiation 2.0000 5 yes
GO:0060259 regulation of feeding behavior 2.0000 5 yes
GO:0072538 T-helper 17 type immune response 2.0000 5 yes
GO:0072540 T-helper 17 cell lineage commitment 2.0000 8 yes
GO:1900015 regulation of cytokine production involved in inflammatory response 2.0000 5 yes
GO:1900017 positive regulation of cytokine production involved in inflammatory response 2.0000 6 yes
GO:1900542 regulation of purine nucleotide metabolic process 2.0000 6 yes
GO:1900543 negative regulation of purine nucleotide metabolic process 2.0000 7 yes
GO:1903578 regulation of ATP metabolic process 2.0000 7 yes
GO:1903579 negative regulation of ATP metabolic process 2.0000 8 yes
GO:1903799 negative regulation of miRNA maturation 2.0000 7 yes
GO:1904683 regulation of metalloendopeptidase activity 2.0000 7 yes
GO:1904685 positive regulation of metalloendopeptidase activity 2.0000 8 yes
GO:1905048 regulation of metallopeptidase activity 2.0000 6 yes
GO:1905050 positive regulation of metallopeptidase activity 2.0000 7 yes
GO:2000634 regulation of primary miRNA processing 2.0000 8 yes
GO:2000635 negative regulation of primary miRNA processing 2.0000 8 yes
GO:2000737 negative regulation of stem cell differentiation 2.0000 6 yes
GO:2001222 regulation of neuron migration 2.0000 6 yes
GO:2001223 negative regulation of neuron migration 2.0000 7 yes
GO:0001754 eye photoreceptor cell differentiation 2.0000 6 yes
GO:0006110 regulation of glycolytic process 2.0000 6 yes
GO:0006140 regulation of nucleotide metabolic process 2.0000 5 yes
GO:0006366 transcription by RNA polymerase II 2.0000 8 yes
GO:0009299 mRNA transcription 2.0000 7 yes
GO:0010677 negative regulation of cellular carbohydrate metabolic process 2.0000 6 yes
GO:0032653 regulation of interleukin-10 production 2.0000 5 yes
GO:0032733 positive regulation of interleukin-10 production 2.0000 6 yes
GO:0033210 leptin-mediated signaling pathway 2.0000 5 yes
GO:0042755 eating behavior 2.0000 4 yes
GO:0042789 mRNA transcription by RNA polymerase II 2.0000 8 yes
GO:0043470 regulation of carbohydrate catabolic process 2.0000 5 yes
GO:0044320 cellular response to leptin stimulus 2.0000 5 yes
GO:0044321 response to leptin 2.0000 4 yes
GO:0045820 negative regulation of glycolytic process 2.0000 6 yes
GO:0045912 negative regulation of carbohydrate metabolic process 2.0000 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in STAT3_HUMAN
DOID:612 primary immunodeficiency disease 4.0000 3 yes
DOID:0050686 organ system cancer 4.0000 3 no
DOID:0080545 hyper IgE syndrome 2.0000 6 yes
DOID:2115 B cell deficiency 2.0000 4 yes
DOID:2959 hyperimmunoglobulin syndrome 2.0000 5 yes
DOID:3261 hyper IgE recurrent infection syndrome 1 2.0000 7 yes
DOID:0050155 sensory system disease 2.0000 3 no
DOID:0060038 specific developmental disorder 2.0000 3 no
DOID:1059 intellectual disability 2.0000 4 no
DOID:10595 Charcot-Marie-Tooth disease 2.0000 6 no
DOID:440 neuromuscular disease 2.0000 5 no
DOID:574 peripheral nervous system disease 2.0000 3 no
DOID:870 neuropathy 2.0000 4 no
DOID:331 central nervous system disease 2.0000 3 no
DOID:0050700 cardiomyopathy 2.0000 4 no
DOID:0060036 intrinsic cardiomyopathy 2.0000 5 no
DOID:114 heart disease 2.0000 3 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TSHR_HUMAN [view interactions] Low throughput no no
CRYAB_HUMAN [view entry] [view interactions] Low throughput yes no
HNF1A_HUMAN [view interactions] Low throughput no no
PDIA3_HUMAN [view entry] [view interactions] Low throughput yes yes
IL6RA_HUMAN [view interactions] Low throughput no no
G45IP_HUMAN [view interactions] Low throughput no yes
E2AK2_HUMAN [view entry] [view interactions] Low throughput yes yes
RBM8A_HUMAN [view interactions] Low throughput no yes
CCR5_HUMAN [view interactions] Low throughput no no
KSYK_HUMAN [view interactions] Low throughput no no
HIF1A_HUMAN [view interactions] Low throughput no no
MET_HUMAN [view interactions] Low throughput no yes
BCL3_HUMAN [view interactions] Low throughput no yes
DNMT1_HUMAN [view interactions] Low throughput no no
RB_HUMAN [view interactions] Low throughput no yes
FGR_HUMAN [view interactions] Low throughput no no
HDAC3_HUMAN [view interactions] Low throughput no yes
PCBP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CEBPB_HUMAN [view interactions] Low throughput no no
FGFR1_HUMAN [view interactions] Low throughput no yes
FGFR2_HUMAN [view interactions] Low throughput no yes
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
TMF1_HUMAN [view interactions] Low throughput no yes
SIAH1_HUMAN [view interactions] Low throughput no yes
SIR1_HUMAN [view interactions] Low throughput no yes
RUNX2_HUMAN [view interactions] Low throughput no no
JAK3_HUMAN [view interactions] Low throughput no no
BHE40_HUMAN [view interactions] Low throughput no yes
STAT3_HUMAN [view entry] [view interactions] Low throughput yes yes
CD44_HUMAN [view interactions] Low throughput no yes
IRAK1_HUMAN [view interactions] Low throughput no yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAF6_HUMAN [view interactions] Low throughput no yes
ZFHX3_HUMAN [view interactions] Low throughput no yes
PIAS3_HUMAN [view interactions] Low throughput no yes
APEX1_HUMAN [view interactions] Low throughput no yes
FER_HUMAN [view interactions] Low throughput no yes
TIF1B_HUMAN [view interactions] Low throughput no yes
HES1_HUMAN [view interactions] Low throughput no no
HES5_HUMAN [view interactions] Low throughput no yes
ZN467_HUMAN [view interactions] Low throughput no no
CYLD_HUMAN [view entry] [view interactions] Low throughput yes yes
SIN3A_HUMAN [view interactions] Low throughput no yes
BRD4_HUMAN [view interactions] Low throughput no yes
CSN5_HUMAN [view interactions] Low throughput no yes
I22R1_HUMAN [view interactions] Low throughput no no
HIC1_HUMAN [view interactions] Low throughput no no
UBP22_HUMAN [view interactions] Low throughput no yes
IKBZ_HUMAN [view interactions] Low throughput no no
GA45A_HUMAN [view interactions] Low throughput no no
ECHM_HUMAN [view interactions] Low throughput no yes
DAPK3_HUMAN [view interactions] Low throughput no yes
NFKB2_HUMAN [view interactions] Low throughput no yes
NLK_HUMAN [view interactions] Low throughput no yes
DAXX_HUMAN [view interactions] Low throughput no yes
IMA5_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
CTR9_HUMAN [view interactions] Low throughput no yes
SH2B1_HUMAN [view interactions] Low throughput no yes
TBXT_HUMAN [view interactions] Low throughput no no
SETD7_HUMAN [view interactions] Low throughput no yes
KDM1A_HUMAN [view interactions] Low throughput no yes
ENPL_HUMAN [view entry] [view interactions] Low throughput yes yes
STMN1_HUMAN [view interactions] Low throughput no yes
MAGC2_HUMAN [view interactions] Low throughput no no
COP1_HUMAN [view interactions] Low throughput no no
ZDH19_HUMAN [view interactions] Low throughput no no
CREB1_HUMAN [view interactions] Low throughput no yes
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
STAT1_HUMAN [view entry] [view interactions] Low throughput yes no
JAK1_HUMAN [view interactions] Low throughput no yes
KHDR1_HUMAN [view interactions] Low throughput no yes
RET_HUMAN [view interactions] Low throughput no yes
ERBB2_HUMAN [view entry] [view interactions] Low throughput yes no
CSF3R_HUMAN [view interactions] Low throughput no yes
TCPG_HUMAN [view entry] [view interactions] Low throughput yes yes
CRTC2_HUMAN [view interactions] Low throughput no yes
M3K7_HUMAN [view interactions] Low throughput no yes
CRTC3_HUMAN [view interactions] Low throughput no no
IL6RB_HUMAN [view interactions] Low throughput no no
ANXA2_HUMAN [view entry] [view interactions] Low throughput yes no
NMI_HUMAN [view interactions] Low throughput no yes
EGFR_HUMAN [view interactions] Low throughput no no
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
HDAC6_HUMAN [view interactions] Low throughput no yes
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPA_HUMAN [view interactions] Low throughput no yes
PTPRT_HUMAN [view entry] [view interactions] Low throughput yes yes
PRDX2_HUMAN [view entry] [view interactions] Low throughput yes yes
THIO_HUMAN [view interactions] Low throughput no yes
TIF1A_HUMAN [view interactions] Low throughput no yes
MK13_HUMAN [view interactions] Low throughput no yes
MYOF_HUMAN [view interactions] Low throughput no yes
MK08_HUMAN [view interactions] Low throughput no yes
KAT2B_HUMAN [view interactions] Low throughput no yes
GOLP3_HUMAN [view interactions] Low throughput no no
OCAD1_HUMAN [view interactions] Low throughput no yes
OCAD2_HUMAN [view interactions] Low throughput no yes
K1C17_HUMAN [view interactions] Low throughput no no
IL3RB_HUMAN [view interactions] Low throughput no no
TRI59_HUMAN [view interactions] Low throughput no no
UBP28_HUMAN [view interactions] Low throughput no yes
TMUB1_HUMAN [view entry] [view interactions] Low throughput yes yes
WWP2_HUMAN [view interactions] Low throughput no no
GLI1_HUMAN [view interactions] Low throughput no no
SOCS3_HUMAN [view interactions] Low throughput no yes
TNAP3_HUMAN [view interactions] Low throughput no yes
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKB_HUMAN [view interactions] Low throughput no yes
TAB3_HUMAN [view interactions] Low throughput no yes
LYN_HUMAN [view entry] [view interactions] Low throughput yes no
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
SOX1_HUMAN [view interactions] Low throughput no no
DIRA3_HUMAN [view interactions] Low throughput no yes
HDAC1_HUMAN [view interactions] Low throughput no no
PRGR_HUMAN [view interactions] Low throughput no no
SP1_HUMAN [view interactions] Low throughput no yes
SUZ12_HUMAN [view interactions] Low throughput no no
EZH2_HUMAN [view interactions] Low throughput no no
CDK6_HUMAN [view interactions] Low throughput no yes
FGFR3_HUMAN [view interactions] Low throughput no yes
HDAC8_HUMAN [view interactions] Low throughput no yes
FZD2_HUMAN [view interactions] Low throughput no no
IL23R_HUMAN [view interactions] Low throughput no yes
FOXP3_HUMAN [view interactions] Low throughput no no
CDK9_HUMAN [view interactions] Low throughput no yes
SMCA4_HUMAN [view interactions] Low throughput no yes
ROCK2_HUMAN [view entry] [view interactions] Low throughput yes yes
JAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
MARH8_HUMAN [view interactions] Low throughput no no
MP2K3_HUMAN [view entry] [view interactions] Low throughput yes yes
MDM2_HUMAN [view interactions] Low throughput no yes
RPR1B_HUMAN [view interactions] Low throughput no yes
KAT2A_HUMAN [view interactions] Low throughput no no
IL2RB_HUMAN [view interactions] Low throughput no no
GTF2I_HUMAN [view interactions] Low throughput no yes
GHR_HUMAN [view interactions] Low throughput no yes
HCK_HUMAN [view entry] [view interactions] Low throughput yes no
RAD_HUMAN [view interactions] Low throughput no yes
KS6A1_HUMAN [view interactions] Low throughput no yes
KS6A3_HUMAN [view entry] [view interactions] Low throughput yes yes
TWST1_HUMAN [view interactions] Low throughput no no
IRF4_HUMAN [view interactions] Low throughput no no
RELB_HUMAN [view interactions] Low throughput no yes
CAH9_HUMAN [view interactions] Low throughput no no
VEGFA_HUMAN [view entry] [view interactions] Low throughput yes yes
PGK1_HUMAN [view entry] [view interactions] Low throughput yes yes
MMP1_HUMAN [view interactions] Low throughput no no
MMP2_HUMAN [view interactions] Low throughput no no
PTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
RRAS2_HUMAN [view interactions] Low throughput no yes
CEP70_HUMAN [view interactions] Low throughput no yes
REN3A_HUMAN [view interactions] Low throughput no yes
CSF1R_HUMAN [view interactions] Low throughput no yes
BMX_HUMAN [view interactions] Low throughput no no
INGR1_HUMAN [view interactions] Low throughput no no
FRK_HUMAN [view interactions] Low throughput no no
RFA2_HUMAN [view interactions] Low throughput no yes
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN1_HUMAN [view interactions] Low throughput no yes
HDAC2_HUMAN [view interactions] Low throughput no yes
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
CDN1A_HUMAN [view interactions] Low throughput no no
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
NFKB1_HUMAN [view interactions] Low throughput no yes
IRAK3_HUMAN [view interactions] Low throughput no yes
ATD3A_HUMAN [view entry] [view interactions] Low throughput yes yes
ELP2_HUMAN [view interactions] Low throughput no yes
RAC1_HUMAN [view entry] [view interactions] Low throughput yes no
JUN_HUMAN [view interactions] Low throughput no yes
PELP1_HUMAN [view interactions] Low throughput no yes
SOCS7_HUMAN [view interactions] Low throughput no yes
ESR1_HUMAN [view interactions] Low throughput no no
FBXW7_HUMAN [view interactions] Low throughput no yes
EPHA5_HUMAN [view interactions] Low throughput no no
CIP4_HUMAN [view interactions] Low throughput no no
ANDR_HUMAN [view interactions] Low throughput no no
MYOD1_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
EP300_HUMAN [view interactions] Low throughput no yes
CBP_HUMAN [view interactions] Low throughput no yes
SMAD1_HUMAN [view interactions] Low throughput no yes
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
IL1AP_HUMAN [view entry] [view interactions] Low throughput yes yes
FES_HUMAN [view entry] [view interactions] Low throughput yes no
NCOA1_HUMAN [view interactions] Low throughput no yes
PTN2_HUMAN [view interactions] Low throughput no yes
CCND1_HUMAN [view interactions] Low throughput no yes
HSPB1_HUMAN [view entry] [view interactions] Low throughput yes no
HS90A_HUMAN [view entry] [view interactions] Low throughput yes yes
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
PML_HUMAN [view interactions] Low throughput no yes
INAR1_HUMAN [view interactions] Low throughput no yes
BANK1_HUMAN [view interactions] High throughput no no
CP110_HUMAN [view interactions] High throughput no yes
FHL2_HUMAN [view interactions] High throughput no yes
AMBP_HUMAN [view interactions] High throughput no no
BICD1_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
CPNS1_HUMAN [view interactions] High throughput no yes
CAN1_HUMAN [view entry] [view interactions] High throughput yes yes
ECH1_HUMAN [view interactions] High throughput no yes
ZEP1_HUMAN [view interactions] High throughput no yes
HLAA_HUMAN [view interactions] High throughput no no
NR4A1_HUMAN [view interactions] High throughput no yes
LAMB2_HUMAN [view interactions] High throughput no yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
2AAB_HUMAN [view interactions] High throughput no yes
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
SIAH2_HUMAN [view interactions] High throughput no no
SORCN_HUMAN [view entry] [view interactions] High throughput yes yes
ST2A1_HUMAN [view interactions] High throughput no no
SCAFB_HUMAN [view interactions] High throughput no yes
RT31_HUMAN [view interactions] High throughput no yes
SPY1_HUMAN [view interactions] High throughput no yes
BCKD_HUMAN [view entry] [view interactions] High throughput yes yes
ZNRD2_HUMAN [view interactions] High throughput no yes
COR1A_HUMAN [view entry] [view interactions] High throughput yes no
FOG2_HUMAN [view interactions] High throughput no yes
ARFP2_HUMAN [view interactions] High throughput no no
GNL3_HUMAN [view interactions] High throughput no yes
SRRT_HUMAN [view interactions] High throughput no yes
SP20H_HUMAN [view interactions] High throughput no yes
OGDHL_HUMAN [view entry] [view interactions] High throughput yes yes
ERBIN_HUMAN [view entry] [view interactions] High throughput yes yes
NIF3L_HUMAN [view interactions] High throughput no yes
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
MORC4_HUMAN [view interactions] High throughput no no
CE120_HUMAN [view interactions] High throughput no no
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
ASXL1_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
CAP7_HUMAN [view interactions] High throughput no no
CCG2_HUMAN [view entry] [view interactions] High throughput yes no
NXPH2_HUMAN [view interactions] High throughput no no
DD19B_HUMAN [view interactions] High throughput no yes
TIRAP_HUMAN [view interactions] High throughput no no
XRP2_HUMAN [view entry] [view interactions] High throughput yes no
TRPV5_HUMAN [view interactions] High throughput no no
WRP73_HUMAN [view interactions] High throughput no no
TCAL1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
ABCG1_HUMAN [view interactions] High throughput no yes
MTG8R_HUMAN [view interactions] High throughput no yes
NUDC1_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
CDK15_HUMAN [view interactions] High throughput no no
LRC32_HUMAN [view interactions] High throughput no no
I20RA_HUMAN [view interactions] High throughput no no
NF2L2_HUMAN [view interactions] High throughput no yes
TB22B_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
PACC1_HUMAN [view interactions] High throughput no no
SYJ2B_HUMAN [view entry] [view interactions] High throughput yes no
MBLC2_HUMAN [view interactions] High throughput no yes
VASN_HUMAN [view interactions] High throughput no yes
C3AR_HUMAN [view interactions] High throughput no no
PVR_HUMAN [view interactions] High throughput no yes
DLK2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
DDR1_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
DUT_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
TRI11_HUMAN [view interactions] High throughput no yes
GAB2_HUMAN [view interactions] High throughput no yes
PRP4B_HUMAN [view interactions] High throughput no yes
TBC9B_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
WDR1_HUMAN [view entry] [view interactions] High throughput yes yes
ZAP70_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
BCR_HUMAN [view entry] [view interactions] High throughput yes yes
STAT2_HUMAN [view interactions] High throughput no yes
UBXN1_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
PRPS1_HUMAN [view entry] [view interactions] High throughput yes no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
IFIH1_HUMAN [view interactions] High throughput no yes
TEX2_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
HOT_HUMAN [view interactions] High throughput no no
HNRPF_HUMAN [view interactions] High throughput no yes
NFS1_HUMAN [view interactions] High throughput no yes
LEG2_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
LAT_HUMAN [view interactions] High throughput no no
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
S2536_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
BAF_HUMAN [view entry] [view interactions] High throughput yes yes
AKT3_HUMAN [view interactions] High throughput no yes
DHE3_HUMAN [view entry] [view interactions] High throughput yes yes
NPC1_HUMAN [view interactions] High throughput no yes
LG3BP_HUMAN [view interactions] High throughput no no
EIF3F_HUMAN [view interactions] High throughput no yes
SYNE2_HUMAN [view interactions] High throughput no no
HNRL1_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
PO2F1_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
PHAG1_HUMAN [view interactions] High throughput no yes
COMP_HUMAN [view interactions] High throughput no no
GLPA_HUMAN [view interactions] High throughput no no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
SPSB4_HUMAN [view interactions] High throughput no no
HECD1_HUMAN [view interactions] High throughput no yes
OR2A4_HUMAN [view interactions] High throughput no no
2ABB_HUMAN [view interactions] High throughput no yes
SEM4C_HUMAN [view entry] [view interactions] High throughput yes no
STX17_HUMAN [view interactions] High throughput no yes
RN115_HUMAN [view interactions] High throughput no yes
CR021_HUMAN [view interactions] High throughput no no
EFMT3_HUMAN [view interactions] High throughput no no
SARAF_HUMAN [view interactions] High throughput no no
PRTN3_HUMAN [view interactions] High throughput no no
PHF11_HUMAN [view interactions] High throughput no no
MBNL1_HUMAN [view interactions] High throughput no yes
PLCA_HUMAN [view interactions] High throughput no yes
EKI2_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
SSBP2_HUMAN [view interactions] High throughput no yes
CCR1_HUMAN [view interactions] High throughput no no
GPR45_HUMAN [view interactions] High throughput no no
EFNB1_HUMAN [view interactions] High throughput no yes
PIGT_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
MMTA2_HUMAN [view interactions] High throughput no yes
SSUH2_HUMAN [view interactions] High throughput no no
M3K13_HUMAN [view interactions] High throughput no yes
RBGP1_HUMAN [view interactions] High throughput no yes
WDFY3_HUMAN [view interactions] High throughput no yes
F117B_HUMAN [view interactions] High throughput no no
TASO2_HUMAN [view interactions] High throughput no yes
RBCC1_HUMAN [view interactions] High throughput no no
MAPK2_HUMAN [view interactions] High throughput no yes
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
ZN281_HUMAN [view interactions] High throughput no no
I22R2_HUMAN [view interactions] High throughput no no
HESX1_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CCD87_HUMAN [view interactions] High throughput no no
SH22A_HUMAN [view interactions] High throughput no no
T4S19_HUMAN [view interactions] High throughput no no
P55G_HUMAN [view interactions] High throughput no yes
GSTCD_HUMAN [view interactions] High throughput no yes
PAQR7_HUMAN [view interactions] High throughput no yes
ZN829_HUMAN [view interactions] High throughput no no
LASP1_HUMAN [view entry] [view interactions] High throughput yes yes
KR107_HUMAN [view interactions] High throughput no no
CAH8_HUMAN [view interactions] High throughput no no
CBL_HUMAN [view interactions] High throughput no yes
NACAD_HUMAN [view interactions] High throughput no yes
KLF15_HUMAN [view interactions] High throughput no yes
BATF3_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
CNDP2_HUMAN [view entry] [view interactions] High throughput yes yes
CTF18_HUMAN [view interactions] High throughput no no
OFCC1_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
TDG_HUMAN [view interactions] High throughput no yes
PA1B2_HUMAN [view interactions] High throughput no yes
LC7L2_HUMAN [view interactions] High throughput no yes
PSMG3_HUMAN [view interactions] High throughput no yes
MNDA_HUMAN [view interactions] High throughput no no
ARFP1_HUMAN [view interactions] High throughput no no
ATF3_HUMAN [view interactions] High throughput no yes
NS1BP_HUMAN [view interactions] High throughput no yes
RBTN2_HUMAN [view interactions] High throughput no yes
MSH2_HUMAN [view interactions] High throughput no yes
BLK_HUMAN [view interactions] High throughput no no
PUS7_HUMAN [view interactions] High throughput no yes
IMDH2_HUMAN [view interactions] High throughput no yes
TBC15_HUMAN [view interactions] High throughput no yes
CREST_HUMAN [view interactions] High throughput no yes
TBCD_HUMAN [view entry] [view interactions] High throughput yes no
STAT6_HUMAN [view interactions] High throughput no yes
IDE_HUMAN [view interactions] High throughput no yes
HXC11_HUMAN [view interactions] High throughput no no
NFYB_HUMAN [view interactions] High throughput no yes
PHS2_HUMAN [view interactions] High throughput no yes
YJEN3_HUMAN [view interactions] High throughput no yes
Z3H7A_HUMAN [view interactions] High throughput no no
STK4_HUMAN [view interactions] High throughput no yes
GBF1_HUMAN [view interactions] High throughput no yes
KIF27_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
LRRF2_HUMAN [view interactions] High throughput no yes
ATG5_HUMAN [view interactions] High throughput no no
AR26L_HUMAN [view interactions] High throughput no no
NAA40_HUMAN [view interactions] High throughput no no
PA24A_HUMAN [view entry] [view interactions] High throughput yes yes
OPTN_HUMAN [view interactions] High throughput no yes
HIF1N_HUMAN [view interactions] High throughput no yes
PGFRB_HUMAN [view interactions] High throughput no yes
PGFRA_HUMAN [view interactions] High throughput no no
STA5B_HUMAN [view interactions] High throughput no yes
RAD50_HUMAN [view interactions] High throughput no yes
SYLC_HUMAN [view interactions] High throughput no yes
HAUS4_HUMAN [view interactions] High throughput no yes
ARFG1_HUMAN [view interactions] High throughput no no
RFLB_HUMAN [view interactions] High throughput no yes
LRC49_HUMAN [view interactions] High throughput no no
TPGS1_HUMAN [view interactions] High throughput no no
COPA_HUMAN [view entry] [view interactions] High throughput yes yes
COPB_HUMAN [view interactions] High throughput no yes
NUP62_HUMAN [view interactions] High throughput no yes
COPB2_HUMAN [view entry] [view interactions] High throughput yes yes
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
RGPD1_HUMAN [view interactions] High throughput no no
SRP72_HUMAN [view interactions] High throughput no yes
COPE_HUMAN [view interactions] High throughput no yes
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
UBC9_HUMAN [view interactions] High throughput no yes
PO6F1_HUMAN [view interactions] High throughput no no
BRWD1_HUMAN [view interactions] High throughput no yes
DOK2_HUMAN [view interactions] High throughput no no
DOK3_HUMAN [view interactions] High throughput no no
MPZL1_HUMAN [view interactions] High throughput no yes
NUFP2_HUMAN [view interactions] High throughput no no
VPS39_HUMAN [view entry] [view interactions] High throughput yes no
ABL2_HUMAN [view entry] [view interactions] High throughput yes yes
DTNA_HUMAN [view entry] [view interactions] High throughput yes yes
P85A_HUMAN [view interactions] High throughput no yes
P85B_HUMAN [view interactions] High throughput no yes
PPARD_HUMAN [view interactions] High throughput no yes
3BP2_HUMAN [view interactions] High throughput no yes
NXT2_HUMAN [view interactions] High throughput no yes
ZN557_HUMAN [view interactions] High throughput no no
P121A_HUMAN [view interactions] High throughput no yes
HAX1_HUMAN [view interactions] High throughput no no
K2C1_HUMAN [view interactions] High throughput no no
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
TNFA_HUMAN [view interactions] Computational no no
PIAS2_HUMAN [view interactions] Computational no yes
MMP3_HUMAN [view interactions] Computational no no
PRLR_HUMAN [view interactions] Computational no no
SOCS4_HUMAN [view interactions] Computational no yes
LMO4_HUMAN [view interactions] Computational no yes
LN28A_HUMAN [view interactions] Computational no no
BCL2_HUMAN [view interactions] Computational no no
HGF_HUMAN [view interactions] Computational no yes
PO5F1_HUMAN [view interactions] Computational no yes
TOM20_HUMAN [view entry] [view interactions] Computational yes yes
CXL10_HUMAN [view interactions] Computational no no
I12R1_HUMAN [view interactions] Computational no no
AKT1_HUMAN [view entry] [view interactions] Computational yes yes
KLF4_HUMAN [view interactions] Computational no no
IL18R_HUMAN [view interactions] Computational no yes
BECN1_HUMAN [view interactions] Computational no yes
IL2_HUMAN [view interactions] Computational no no
STA5A_HUMAN [view interactions] Computational no no
TNFL6_HUMAN [view interactions] Computational no yes
NTF3_HUMAN [view interactions] Computational no no
SALL4_HUMAN [view interactions] Computational no no
IL13_HUMAN [view interactions] Computational no no
CASP3_HUMAN [view interactions] Computational no yes
PGH2_HUMAN [view interactions] Computational no no
NTRK3_HUMAN [view entry] [view interactions] Computational yes yes
NFAC1_HUMAN [view interactions] Computational no no
KIT_HUMAN [view interactions] Computational no no
RORG_HUMAN [view interactions] Computational no no
IL21R_HUMAN [view interactions] Computational no no
NTF4_HUMAN [view interactions] Computational no no
CCL3_HUMAN [view interactions] Computational no no
CCL22_HUMAN [view interactions] Computational no no
IL10_HUMAN [view interactions] Computational no no
FGFR4_HUMAN [view interactions] Computational no no
FLT3_HUMAN [view interactions] Computational no no
SDC2_HUMAN [view interactions] Computational no yes
PRL_HUMAN [view interactions] Computational no no
MYCD_HUMAN [view interactions] Computational no yes
I10R2_HUMAN [view interactions] Computational no no
LPPRC_HUMAN [view entry] [view interactions] Computational yes yes
IRF1_HUMAN [view interactions] Computational no yes
IL1R1_HUMAN [view interactions] Computational no no
IL18_HUMAN [view interactions] Computational no yes
I27RA_HUMAN [view interactions] Computational no no
PK3CA_HUMAN [view entry] [view interactions] Computational yes yes
CD80_HUMAN [view interactions] Computational no no
ONCM_HUMAN [view interactions] Computational no no
MP2K1_HUMAN [view entry] [view interactions] Computational yes yes
PPIF_HUMAN [view interactions] Computational no no
IRF9_HUMAN [view interactions] Computational no yes
IMA3_HUMAN [view interactions] Computational no yes
CSF3_HUMAN [view interactions] Computational no no
IL1B_HUMAN [view interactions] Computational no no
TNR1B_HUMAN [view interactions] Computational no no
RHOU_HUMAN [view interactions] Computational no no
SAA1_HUMAN [view interactions] Computational no no