SNX27_HUMAN
Evidence for PS localization
Functions
Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNX27_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 26.9231 | 4 | no |
| GO:0046872 | metal ion binding | 26.1538 | 5 | no |
| GO:0035091 | phosphatidylinositol binding | 6.1538 | 4 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 2.3077 | 5 | yes |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | 1.5385 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNX27_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.3846 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 46.1538 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 42.3077 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 39.2308 | 4 | no |
| GO:0010646 | regulation of cell communication | 38.4615 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 36.9231 | 4 | no |
| GO:0022607 | cellular component assembly | 36.1538 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.1538 | 4 | no |
| GO:0008104 | protein localization | 35.3846 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 35.3846 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 30.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 30.0000 | 4 | no |
| GO:0006996 | organelle organization | 30.0000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.4615 | 5 | no |
| GO:0010468 | regulation of gene expression | 27.6923 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.6923 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 27.6923 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.9231 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.1538 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.3846 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 24.6154 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.6154 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.6154 | 5 | no |
| GO:0071702 | organic substance transport | 23.8462 | 4 | yes |
| GO:0051049 | regulation of transport | 23.8462 | 4 | no |
| GO:0009894 | regulation of catabolic process | 23.0769 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.0769 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 22.3077 | 4 | no |
| GO:0033043 | regulation of organelle organization | 22.3077 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 22.3077 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.3077 | 4 | no |
| GO:0071705 | nitrogen compound transport | 21.5385 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 21.5385 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.5385 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.7692 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.7692 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.7692 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.7692 | 4 | no |
| GO:0043933 | protein-containing complex organization | 20.7692 | 4 | no |
| GO:0015031 | protein transport | 17.6923 | 4 | yes |
| GO:0006886 | intracellular protein transport | 13.0769 | 4 | yes |
| GO:0007034 | vacuolar transport | 8.4615 | 4 | yes |
| GO:0007041 | lysosomal transport | 8.4615 | 5 | yes |
| GO:0032456 | endocytic recycling | 5.3846 | 4 | yes |
| GO:0001767 | establishment of lymphocyte polarity | 1.5385 | 4 | yes |
| GO:0001770 | establishment of natural killer cell polarity | 1.5385 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LYAM3_HUMAN | [view interactions] | Low throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | Low throughput | no | yes |
| KCNJ9_HUMAN | [view interactions] | Low throughput | no | yes |
| PTH1R_HUMAN | [view interactions] | Low throughput | no | no |
| LRC3B_HUMAN | [view interactions] | Low throughput | no | yes |
| ACE2_HUMAN | [view interactions] | Low throughput | no | no |
| EEA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MRP4_HUMAN | [view interactions] | Low throughput | no | no |
| INSR_HUMAN | [view interactions] | Low throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OTUL_HUMAN | [view interactions] | Low throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DGKZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GTR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDKA1_HUMAN | [view interactions] | High throughput | no | yes |
| XIAP_HUMAN | [view interactions] | High throughput | no | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPA_HUMAN | [view interactions] | High throughput | no | yes |
| CEBPZ_HUMAN | [view interactions] | High throughput | no | no |
| S53A1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPU_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHSS2_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB5_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC3HD_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| ZFAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN639_HUMAN | [view interactions] | High throughput | no | yes |
| CO5A3_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| KC1G2_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CWC22_HUMAN | [view interactions] | High throughput | no | yes |
| F10C1_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP16_HUMAN | [view interactions] | High throughput | no | yes |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX40_HUMAN | [view interactions] | High throughput | no | yes |
| ERCC5_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBED1_HUMAN | [view interactions] | High throughput | no | yes |
| DPP2_HUMAN | [view interactions] | High throughput | no | yes |
| NUCB2_HUMAN | [view interactions] | High throughput | no | yes |
| DTL_HUMAN | [view interactions] | High throughput | no | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F7_HUMAN | [view interactions] | High throughput | no | no |
| K0930_HUMAN | [view interactions] | High throughput | no | yes |
| EHD2_HUMAN | [view interactions] | High throughput | no | no |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| P3H2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| TAB1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOF1_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERC6L_HUMAN | [view interactions] | High throughput | no | yes |
| MARC2_HUMAN | [view interactions] | High throughput | no | no |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| AMERL_HUMAN | [view interactions] | High throughput | no | no |
| EVI5_HUMAN | [view interactions] | High throughput | no | yes |
| CA043_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODR4_HUMAN | [view interactions] | High throughput | no | yes |
| ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WAC2C_HUMAN | [view interactions] | High throughput | no | yes |
| S4A7_HUMAN | [view interactions] | High throughput | no | no |
| RIPR1_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FA83B_HUMAN | [view interactions] | High throughput | no | no |
| SPIN1_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF8_HUMAN | [view interactions] | High throughput | no | yes |
| CIA2B_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FBX3_HUMAN | [view interactions] | High throughput | no | no |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| FCSD2_HUMAN | [view interactions] | High throughput | no | no |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| FEZ2_HUMAN | [view interactions] | High throughput | no | yes |
| WASH1_HUMAN | [view interactions] | High throughput | no | yes |
| FNBP1_HUMAN | [view interactions] | High throughput | no | yes |
| WIPI3_HUMAN | [view interactions] | High throughput | no | no |
| FBP1L_HUMAN | [view interactions] | High throughput | no | yes |
| VPS29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXP4_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GATD1_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GKAP1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| GOLP3_HUMAN | [view interactions] | High throughput | no | no |
| GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPX8_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| TF3C5_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLAK2_HUMAN | [view interactions] | High throughput | no | no |
| KS6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC8_HUMAN | [view interactions] | High throughput | no | yes |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |
| HTR5A_HUMAN | [view interactions] | High throughput | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HTR5B_HUMAN | [view interactions] | High throughput | no | yes |
| GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HM20B_HUMAN | [view interactions] | High throughput | no | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN5_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| PHLP2_HUMAN | [view interactions] | High throughput | no | yes |
| HTSF1_HUMAN | [view interactions] | High throughput | no | yes |
| SNX2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| GILT_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRFN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRPM7_HUMAN | [view interactions] | High throughput | no | no |
| IPO8_HUMAN | [view interactions] | High throughput | no | no |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIGD6_HUMAN | [view interactions] | High throughput | no | no |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| JAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCTD2_HUMAN | [view interactions] | High throughput | no | no |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD5_HUMAN | [view interactions] | High throughput | no | no |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| PLGT3_HUMAN | [view interactions] | High throughput | no | no |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| WASC5_HUMAN | [view interactions] | High throughput | no | yes |
| SH2B3_HUMAN | [view interactions] | High throughput | no | yes |
| WASC4_HUMAN | [view interactions] | High throughput | no | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| KIF22_HUMAN | [view interactions] | High throughput | no | no |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| KIF3C_HUMAN | [view interactions] | High throughput | no | no |
| SLIK6_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| SHF_HUMAN | [view interactions] | High throughput | no | no |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIX1L_HUMAN | [view interactions] | High throughput | no | no |
| STAT2_HUMAN | [view interactions] | High throughput | no | yes |
| LMBD2_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGRL1_HUMAN | [view interactions] | High throughput | no | no |
| STAP2_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STAP1_HUMAN | [view interactions] | High throughput | no | no |
| LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| STAT6_HUMAN | [view interactions] | High throughput | no | yes |
| LSM3_HUMAN | [view interactions] | High throughput | no | yes |
| TENS2_HUMAN | [view interactions] | High throughput | no | no |
| LSM7_HUMAN | [view interactions] | High throughput | no | yes |
| TENS3_HUMAN | [view interactions] | High throughput | no | no |
| LTBP1_HUMAN | [view interactions] | High throughput | no | no |
| TYK2_HUMAN | [view interactions] | High throughput | no | no |
| MA2B1_HUMAN | [view interactions] | High throughput | no | yes |
| TXK_HUMAN | [view interactions] | High throughput | no | no |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| PTHD1_HUMAN | [view interactions] | High throughput | no | no |
| MK12_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF1_HUMAN | [view interactions] | High throughput | no | yes |
| SIN1_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAPK5_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| AKT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGAP_HUMAN | [view interactions] | High throughput | no | yes |
| BPL1_HUMAN | [view interactions] | High throughput | no | yes |
| MICA3_HUMAN | [view interactions] | High throughput | no | yes |
| PLPL3_HUMAN | [view interactions] | High throughput | no | no |
| MICU2_HUMAN | [view interactions] | High throughput | no | yes |
| SYT16_HUMAN | [view interactions] | High throughput | no | yes |
| MRTFA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAXX_HUMAN | [view interactions] | High throughput | no | yes |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPIP3_HUMAN | [view interactions] | High throughput | no | yes |
| MOB1A_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| MPP9_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| RM16_HUMAN | [view interactions] | High throughput | no | yes |
| RT27_HUMAN | [view interactions] | High throughput | no | yes |
| PIBF1_HUMAN | [view interactions] | High throughput | no | yes |
| MSRB2_HUMAN | [view interactions] | High throughput | no | no |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTM1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMRC_HUMAN | [view interactions] | High throughput | no | yes |
| MB12A_HUMAN | [view interactions] | High throughput | no | yes |
| MYCBP_HUMAN | [view interactions] | High throughput | no | yes |
| VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASF1_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG8_HUMAN | [view interactions] | High throughput | no | yes |
| CDK16_HUMAN | [view interactions] | High throughput | no | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USB1_HUMAN | [view interactions] | High throughput | no | yes |
| NLGNX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOA1_HUMAN | [view interactions] | High throughput | no | no |
| NOC4L_HUMAN | [view interactions] | High throughput | no | no |
| CDS1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CERU_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CO3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| BPIA1_HUMAN | [view interactions] | High throughput | no | no |
| NUCB1_HUMAN | [view interactions] | High throughput | no | yes |
| CO4A_HUMAN | [view interactions] | High throughput | no | no |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| TRFL_HUMAN | [view interactions] | High throughput | no | no |
| NUP85_HUMAN | [view interactions] | High throughput | no | yes |
| PROL4_HUMAN | [view interactions] | High throughput | no | no |
| NYAP2_HUMAN | [view interactions] | High throughput | no | no |
| FIG4_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| A1AT_HUMAN | [view interactions] | High throughput | no | no |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIGR_HUMAN | [view interactions] | High throughput | no | no |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDE8B_HUMAN | [view interactions] | High throughput | no | no |
| LACRT_HUMAN | [view interactions] | High throughput | no | no |
| PDGFA_HUMAN | [view interactions] | High throughput | no | yes |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| F262_HUMAN | [view interactions] | High throughput | no | no |
| FIBA_HUMAN | [view interactions] | High throughput | no | no |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| FIBG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 6PGL_HUMAN | [view interactions] | High throughput | no | yes |
| FETUA_HUMAN | [view interactions] | High throughput | no | no |
| PHLA3_HUMAN | [view interactions] | High throughput | no | yes |
| SG2A1_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| LRC36_HUMAN | [view interactions] | High throughput | no | no |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| GP156_HUMAN | [view interactions] | High throughput | no | no |
| PI51A_HUMAN | [view interactions] | High throughput | no | yes |
| MRAP2_HUMAN | [view interactions] | High throughput | no | no |
| PITH1_HUMAN | [view interactions] | High throughput | no | yes |
| BPIB1_HUMAN | [view interactions] | High throughput | no | no |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NGAL_HUMAN | [view interactions] | High throughput | no | no |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| PRSR2_HUMAN | [view interactions] | High throughput | no | yes |
| PLCB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LEG1H_HUMAN | [view interactions] | High throughput | no | no |
| PLD1_HUMAN | [view interactions] | High throughput | no | no |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| PKHA2_HUMAN | [view interactions] | High throughput | no | no |
| TAFA3_HUMAN | [view interactions] | High throughput | no | no |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| CYTN_HUMAN | [view interactions] | High throughput | no | no |
| DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
| DMBT1_HUMAN | [view interactions] | High throughput | no | no |
| RPP29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTHY_HUMAN | [view interactions] | High throughput | no | no |
| PPHLN_HUMAN | [view interactions] | High throughput | no | yes |
| PAUF_HUMAN | [view interactions] | High throughput | no | no |
| PPIL2_HUMAN | [view interactions] | High throughput | no | yes |
| IGJ_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KNG1_HUMAN | [view interactions] | High throughput | no | no |
| PP4C_HUMAN | [view interactions] | High throughput | no | yes |
| SG1D1_HUMAN | [view interactions] | High throughput | no | no |
| PP4R2_HUMAN | [view interactions] | High throughput | no | yes |
| CRDL1_HUMAN | [view interactions] | High throughput | no | no |
| PRCC_HUMAN | [view interactions] | High throughput | no | yes |
| IGLL5_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| PKRI1_HUMAN | [view interactions] | High throughput | no | no |
| LYSC_HUMAN | [view interactions] | High throughput | no | no |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| LCN1_HUMAN | [view interactions] | High throughput | no | no |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| CYTS_HUMAN | [view interactions] | High throughput | no | no |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPGF6_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM10_HUMAN | [view interactions] | High throughput | no | yes |
| RBM5_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| RBM6_HUMAN | [view interactions] | High throughput | no | yes |
| ATP7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| ORN_HUMAN | [view interactions] | High throughput | no | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| STEA3_HUMAN | [view interactions] | High throughput | no | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| KDIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPP30_HUMAN | [view interactions] | High throughput | no | yes |
| MARH1_HUMAN | [view interactions] | High throughput | no | yes |
| RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCL25_HUMAN | [view interactions] | High throughput | no | no |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPXN4_HUMAN | [view interactions] | High throughput | no | no |
| RWD2B_HUMAN | [view interactions] | High throughput | no | no |
| TMM74_HUMAN | [view interactions] | High throughput | no | no |
| S10AG_HUMAN | [view interactions] | High throughput | no | no |
| Z512B_HUMAN | [view interactions] | High throughput | no | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APOA2_HUMAN | [view interactions] | High throughput | no | no |
| SCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVA1B_HUMAN | [view interactions] | High throughput | no | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| CC018_HUMAN | [view interactions] | High throughput | no | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| VTDB_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| TANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24B_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
| CART_HUMAN | [view interactions] | High throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F124A_HUMAN | [view interactions] | High throughput | no | no |
| SHKB1_HUMAN | [view interactions] | High throughput | no | yes |
| GREM2_HUMAN | [view interactions] | High throughput | no | no |
| S12A4_HUMAN | [view interactions] | High throughput | no | yes |
| TGM1_HUMAN | [view interactions] | High throughput | no | no |
| MOT1_HUMAN | [view interactions] | High throughput | no | no |
| KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF1A_HUMAN | [view interactions] | High throughput | no | no |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| CSN9_HUMAN | [view interactions] | High throughput | no | yes |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NK3R_HUMAN | [view interactions] | High throughput | no | no |
| SLIK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDD2L_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD2_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP1_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
| SMYD3_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAAS_HUMAN | [view interactions] | High throughput | no | yes |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCA7_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABTB2_HUMAN | [view interactions] | High throughput | no | yes |
| SPIN3_HUMAN | [view interactions] | High throughput | no | yes |
| ACAP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPIN4_HUMAN | [view interactions] | High throughput | no | no |
| ADDA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| AFTIN_HUMAN | [view interactions] | High throughput | no | yes |
| SRS10_HUMAN | [view interactions] | High throughput | no | yes |
| GDAH_HUMAN | [view interactions] | High throughput | no | no |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHDC1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| STK19_HUMAN | [view interactions] | High throughput | no | no |
| AKA10_HUMAN | [view interactions] | High throughput | no | no |
| STK38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR27_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| SYNJ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR50_HUMAN | [view interactions] | High throughput | no | no |
| TAB2_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| TAB3_HUMAN | [view interactions] | High throughput | no | yes |
| ANO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCD5_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEAN2_HUMAN | [view interactions] | High throughput | no | no |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BGH3_HUMAN | [view interactions] | High throughput | no | no |
| RHG42_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR1_HUMAN | [view interactions] | High throughput | no | no |
| ARI1A_HUMAN | [view interactions] | High throughput | no | yes |
| THEM6_HUMAN | [view interactions] | High throughput | no | no |
| ARI5B_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASND1_HUMAN | [view interactions] | High throughput | no | yes |
| TLL2_HUMAN | [view interactions] | High throughput | no | no |
| ATAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM209_HUMAN | [view interactions] | High throughput | no | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| TM45A_HUMAN | [view interactions] | High throughput | no | no |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF7_HUMAN | [view interactions] | High throughput | no | yes |
| SPF27_HUMAN | [view interactions] | High throughput | no | yes |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| BCL10_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
| BRCC3_HUMAN | [view interactions] | High throughput | no | no |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| SEN34_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| TTC17_HUMAN | [view interactions] | High throughput | no | yes |
| BT3L4_HUMAN | [view interactions] | High throughput | no | yes |
| TTC7A_HUMAN | [view interactions] | High throughput | no | yes |
| BUD13_HUMAN | [view interactions] | High throughput | no | yes |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPNDC_HUMAN | [view interactions] | High throughput | no | yes |
| UB2E1_HUMAN | [view interactions] | High throughput | no | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTL26_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| C1R_HUMAN | [view interactions] | High throughput | no | no |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CF298_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE024_HUMAN | [view interactions] | High throughput | no | yes |
| UBP25_HUMAN | [view interactions] | High throughput | no | yes |
| CH033_HUMAN | [view interactions] | High throughput | no | yes |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| US6NL_HUMAN | [view interactions] | High throughput | no | yes |
| CAMP3_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VANG1_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| CCD34_HUMAN | [view interactions] | High throughput | no | no |
| WAPL_HUMAN | [view interactions] | High throughput | no | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| CCZ1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |