SNX27_HUMAN
Evidence for PS localization
Functions
Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNX27_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 25.4237 | 4 | no |
| GO:0035091 | phosphatidylinositol binding | 8.4746 | 4 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 5.0847 | 5 | yes |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | 3.3898 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNX27_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.2373 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.7627 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 41.5254 | 4 | no |
| GO:0010646 | regulation of cell communication | 36.4407 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 36.4407 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 36.4407 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 36.4407 | 4 | no |
| GO:0022607 | cellular component assembly | 35.5932 | 4 | no |
| GO:0009966 | regulation of signal transduction | 34.7458 | 4 | no |
| GO:0008104 | protein localization | 34.7458 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 33.8983 | 4 | no |
| GO:0006996 | organelle organization | 31.3559 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 29.6610 | 5 | no |
| GO:0051049 | regulation of transport | 28.8136 | 4 | no |
| GO:0071702 | organic substance transport | 28.8136 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 27.9661 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.1186 | 5 | no |
| GO:0071705 | nitrogen compound transport | 26.2712 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 25.4237 | 4 | yes |
| GO:0010468 | regulation of gene expression | 25.4237 | 5 | no |
| GO:0033043 | regulation of organelle organization | 24.5763 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 24.5763 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.7288 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.7288 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.7288 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.7288 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 23.7288 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.7288 | 5 | no |
| GO:0015031 | protein transport | 23.7288 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 23.7288 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 23.7288 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 22.8814 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.8814 | 4 | no |
| GO:0009894 | regulation of catabolic process | 22.8814 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.0339 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 21.1864 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.1864 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.1864 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 20.3390 | 5 | no |
| GO:0006886 | intracellular protein transport | 17.7966 | 4 | yes |
| GO:0016197 | endosomal transport | 13.5593 | 4 | yes |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 8.4746 | 4 | yes |
| GO:0007034 | vacuolar transport | 6.7797 | 4 | yes |
| GO:0007041 | lysosomal transport | 6.7797 | 5 | yes |
| GO:0032456 | endocytic recycling | 6.7797 | 5 | yes |
| GO:0008333 | endosome to lysosome transport | 4.2373 | 5 | yes |
| GO:0001767 | establishment of lymphocyte polarity | 1.6949 | 4 | yes |
| GO:0001770 | establishment of natural killer cell polarity | 1.6949 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SNX27_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 5.0847 | 3 | no |
| DOID:1289 | neurodegenerative disease | 4.2373 | 4 | no |
| DOID:231 | motor neuron disease | 2.5424 | 5 | no |
| DOID:936 | brain disease | 2.5424 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.6949 | 3 | no |
| DOID:12377 | spinal muscular atrophy | 1.6949 | 6 | no |
| DOID:332 | amyotrophic lateral sclerosis | 1.6949 | 6 | no |
| DOID:0050701 | electroclinical syndrome | 1.6949 | 6 | no |
| DOID:0112202 | developmental and epileptic encephalopathy | 1.6949 | 7 | no |
| DOID:1826 | epilepsy | 1.6949 | 5 | no |
| DOID:0050890 | synucleinopathy | 1.6949 | 5 | no |
| DOID:14330 | Parkinsons disease | 1.6949 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KCNJ9_HUMAN | [view interactions] | Low throughput | no | yes |
| PTH1R_HUMAN | [view interactions] | Low throughput | no | no |
| LRC3B_HUMAN | [view interactions] | Low throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | Low throughput | no | yes |
| EEA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MRP4_HUMAN | [view interactions] | Low throughput | no | no |
| INSR_HUMAN | [view interactions] | Low throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OTUL_HUMAN | [view interactions] | Low throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DGKZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GTR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LYAM3_HUMAN | [view interactions] | Low throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GOLP3_HUMAN | [view interactions] | High throughput | no | no |
| GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| GPX8_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF3C5_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKAP2_HUMAN | [view interactions] | High throughput | no | no |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC8_HUMAN | [view interactions] | High throughput | no | yes |
| SNX2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HTR5A_HUMAN | [view interactions] | High throughput | no | no |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| HTR5B_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HM20B_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN5_HUMAN | [view interactions] | High throughput | no | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| HTSF1_HUMAN | [view interactions] | High throughput | no | yes |
| GILT_HUMAN | [view interactions] | High throughput | no | no |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| IPO8_HUMAN | [view interactions] | High throughput | no | no |
| PHLP2_HUMAN | [view interactions] | High throughput | no | yes |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JAK1_HUMAN | [view interactions] | High throughput | no | yes |
| TRPM7_HUMAN | [view interactions] | High throughput | no | no |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| KBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| TIGD6_HUMAN | [view interactions] | High throughput | no | no |
| KCTD2_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD5_HUMAN | [view interactions] | High throughput | no | no |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLGT3_HUMAN | [view interactions] | High throughput | no | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC5_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| WASC4_HUMAN | [view interactions] | High throughput | no | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF22_HUMAN | [view interactions] | High throughput | no | no |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| KIF3C_HUMAN | [view interactions] | High throughput | no | no |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| SH2B3_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| LIX1L_HUMAN | [view interactions] | High throughput | no | no |
| SLIK6_HUMAN | [view interactions] | High throughput | no | yes |
| LMBD2_HUMAN | [view interactions] | High throughput | no | yes |
| SHF_HUMAN | [view interactions] | High throughput | no | no |
| AGRL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
| STAP1_HUMAN | [view interactions] | High throughput | no | no |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| STAP2_HUMAN | [view interactions] | High throughput | no | yes |
| LSM3_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LSM7_HUMAN | [view interactions] | High throughput | no | yes |
| STAT2_HUMAN | [view interactions] | High throughput | no | yes |
| LTBP1_HUMAN | [view interactions] | High throughput | no | no |
| STAT6_HUMAN | [view interactions] | High throughput | no | yes |
| MA2B1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT4_HUMAN | [view interactions] | High throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| TNS2_HUMAN | [view interactions] | High throughput | no | no |
| MK12_HUMAN | [view interactions] | High throughput | no | no |
| TYK2_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| TXK_HUMAN | [view interactions] | High throughput | no | no |
| SIN1_HUMAN | [view interactions] | High throughput | no | yes |
| TENS3_HUMAN | [view interactions] | High throughput | no | no |
| MAPK5_HUMAN | [view interactions] | High throughput | no | yes |
| PTHD1_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| MGAP_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF1_HUMAN | [view interactions] | High throughput | no | yes |
| MICA3_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MICU2_HUMAN | [view interactions] | High throughput | no | yes |
| AKT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRTFA_HUMAN | [view interactions] | High throughput | no | yes |
| BPL1_HUMAN | [view interactions] | High throughput | no | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| PLPL3_HUMAN | [view interactions] | High throughput | no | no |
| MOB1A_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| MPP9_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| RM16_HUMAN | [view interactions] | High throughput | no | yes |
| PIBF1_HUMAN | [view interactions] | High throughput | no | yes |
| RT27_HUMAN | [view interactions] | High throughput | no | yes |
| MSRB2_HUMAN | [view interactions] | High throughput | no | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTM1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMRC_HUMAN | [view interactions] | High throughput | no | yes |
| MB12A_HUMAN | [view interactions] | High throughput | no | yes |
| VP26B_HUMAN | [view interactions] | High throughput | no | yes |
| MYCBP_HUMAN | [view interactions] | High throughput | no | yes |
| RASF1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK16_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG8_HUMAN | [view interactions] | High throughput | no | yes |
| USB1_HUMAN | [view interactions] | High throughput | no | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOA1_HUMAN | [view interactions] | High throughput | no | no |
| NLGNX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDS1_HUMAN | [view interactions] | High throughput | no | yes |
| NOC4L_HUMAN | [view interactions] | High throughput | no | no |
| CERU_HUMAN | [view interactions] | High throughput | no | no |
| PSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CO3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BPIA1_HUMAN | [view interactions] | High throughput | no | no |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| CO4A_HUMAN | [view interactions] | High throughput | no | no |
| NUCB1_HUMAN | [view interactions] | High throughput | no | yes |
| TRFL_HUMAN | [view interactions] | High throughput | no | no |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| PROL4_HUMAN | [view interactions] | High throughput | no | no |
| NUP85_HUMAN | [view interactions] | High throughput | no | yes |
| FIG4_HUMAN | [view interactions] | High throughput | no | yes |
| NYAP2_HUMAN | [view interactions] | High throughput | no | no |
| A1AT_HUMAN | [view interactions] | High throughput | no | no |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| PIGR_HUMAN | [view interactions] | High throughput | no | no |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LACRT_HUMAN | [view interactions] | High throughput | no | no |
| PDE8B_HUMAN | [view interactions] | High throughput | no | no |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| PDGFA_HUMAN | [view interactions] | High throughput | no | yes |
| FIBA_HUMAN | [view interactions] | High throughput | no | no |
| F262_HUMAN | [view interactions] | High throughput | no | no |
| FIBG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| FETUA_HUMAN | [view interactions] | High throughput | no | no |
| 6PGL_HUMAN | [view interactions] | High throughput | no | yes |
| SG2A1_HUMAN | [view interactions] | High throughput | no | no |
| PHLA3_HUMAN | [view interactions] | High throughput | no | yes |
| LRC36_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| GP156_HUMAN | [view interactions] | High throughput | no | no |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| MRAP2_HUMAN | [view interactions] | High throughput | no | no |
| PI51A_HUMAN | [view interactions] | High throughput | no | yes |
| BPIB1_HUMAN | [view interactions] | High throughput | no | no |
| PITH1_HUMAN | [view interactions] | High throughput | no | yes |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| NGAL_HUMAN | [view interactions] | High throughput | no | no |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRSR2_HUMAN | [view interactions] | High throughput | no | yes |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG1H_HUMAN | [view interactions] | High throughput | no | no |
| PLCB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| PLD1_HUMAN | [view interactions] | High throughput | no | no |
| TAFA3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA2_HUMAN | [view interactions] | High throughput | no | no |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| CYTN_HUMAN | [view interactions] | High throughput | no | no |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| DMBT1_HUMAN | [view interactions] | High throughput | no | no |
| DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
| TTHY_HUMAN | [view interactions] | High throughput | no | no |
| RPP29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZG16B_HUMAN | [view interactions] | High throughput | no | no |
| PPHLN_HUMAN | [view interactions] | High throughput | no | yes |
| IGJ_HUMAN | [view interactions] | High throughput | no | no |
| PPIL2_HUMAN | [view interactions] | High throughput | no | yes |
| KNG1_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SG1D1_HUMAN | [view interactions] | High throughput | no | no |
| PP4C_HUMAN | [view interactions] | High throughput | no | yes |
| CRDL1_HUMAN | [view interactions] | High throughput | no | no |
| PP4R2_HUMAN | [view interactions] | High throughput | no | yes |
| IGLL5_HUMAN | [view interactions] | High throughput | no | no |
| PRCC_HUMAN | [view interactions] | High throughput | no | yes |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| LYSC_HUMAN | [view interactions] | High throughput | no | no |
| PKRI1_HUMAN | [view interactions] | High throughput | no | no |
| LCN1_HUMAN | [view interactions] | High throughput | no | no |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| CYTS_HUMAN | [view interactions] | High throughput | no | no |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPGF6_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM10_HUMAN | [view interactions] | High throughput | no | yes |
| RBM5_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| RBM6_HUMAN | [view interactions] | High throughput | no | yes |
| ATP7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| ORN_HUMAN | [view interactions] | High throughput | no | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| STEA3_HUMAN | [view interactions] | High throughput | no | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| KDIS_HUMAN | [view interactions] | High throughput | no | yes |
| ROCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPP30_HUMAN | [view interactions] | High throughput | no | yes |
| MARH1_HUMAN | [view interactions] | High throughput | no | yes |
| RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCL25_HUMAN | [view interactions] | High throughput | no | no |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPXN4_HUMAN | [view interactions] | High throughput | no | no |
| RWD2B_HUMAN | [view interactions] | High throughput | no | no |
| TMM74_HUMAN | [view interactions] | High throughput | no | no |
| S10AG_HUMAN | [view interactions] | High throughput | no | no |
| Z512B_HUMAN | [view interactions] | High throughput | no | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APOA2_HUMAN | [view interactions] | High throughput | no | no |
| SCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVA1B_HUMAN | [view interactions] | High throughput | no | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| CC018_HUMAN | [view interactions] | High throughput | no | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| VTDB_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| TANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24B_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
| CART_HUMAN | [view interactions] | High throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F124A_HUMAN | [view interactions] | High throughput | no | no |
| SHKB1_HUMAN | [view interactions] | High throughput | no | yes |
| GREM2_HUMAN | [view interactions] | High throughput | no | no |
| S12A4_HUMAN | [view interactions] | High throughput | no | yes |
| TGM1_HUMAN | [view interactions] | High throughput | no | no |
| MOT1_HUMAN | [view interactions] | High throughput | no | no |
| KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF1A_HUMAN | [view interactions] | High throughput | no | no |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| CSN9_HUMAN | [view interactions] | High throughput | no | yes |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NK3R_HUMAN | [view interactions] | High throughput | no | no |
| SLIK5_HUMAN | [view interactions] | High throughput | no | no |
| PDD2L_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD2_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP1_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
| SMYD3_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAAS_HUMAN | [view interactions] | High throughput | no | yes |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCA7_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABTB2_HUMAN | [view interactions] | High throughput | no | yes |
| SPIN3_HUMAN | [view interactions] | High throughput | no | yes |
| ACAP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPIN4_HUMAN | [view interactions] | High throughput | no | no |
| ADDA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| AFTIN_HUMAN | [view interactions] | High throughput | no | yes |
| SRS10_HUMAN | [view interactions] | High throughput | no | yes |
| SPEB_HUMAN | [view interactions] | High throughput | no | no |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHDC1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| STK19_HUMAN | [view interactions] | High throughput | no | no |
| AKA10_HUMAN | [view interactions] | High throughput | no | no |
| STK38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR27_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| SYNJ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR50_HUMAN | [view interactions] | High throughput | no | no |
| TAB2_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| TAB3_HUMAN | [view interactions] | High throughput | no | yes |
| ANO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M1_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD5_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEAN2_HUMAN | [view interactions] | High throughput | no | no |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BGH3_HUMAN | [view interactions] | High throughput | no | no |
| RHG42_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR1_HUMAN | [view interactions] | High throughput | no | no |
| ARI1A_HUMAN | [view interactions] | High throughput | no | yes |
| THEM6_HUMAN | [view interactions] | High throughput | no | no |
| ARI5B_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASND1_HUMAN | [view interactions] | High throughput | no | yes |
| TLL2_HUMAN | [view interactions] | High throughput | no | no |
| ATAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM209_HUMAN | [view interactions] | High throughput | no | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| TM45A_HUMAN | [view interactions] | High throughput | no | no |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF7_HUMAN | [view interactions] | High throughput | no | yes |
| SPF27_HUMAN | [view interactions] | High throughput | no | yes |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| BCL10_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
| BRCC3_HUMAN | [view interactions] | High throughput | no | no |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| SEN34_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| TTC17_HUMAN | [view interactions] | High throughput | no | yes |
| BT3L4_HUMAN | [view interactions] | High throughput | no | yes |
| TTC7A_HUMAN | [view interactions] | High throughput | no | yes |
| BUD13_HUMAN | [view interactions] | High throughput | no | yes |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPNDC_HUMAN | [view interactions] | High throughput | no | yes |
| UB2E1_HUMAN | [view interactions] | High throughput | no | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| MTL26_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| C1R_HUMAN | [view interactions] | High throughput | no | no |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CF298_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE024_HUMAN | [view interactions] | High throughput | no | yes |
| UBP25_HUMAN | [view interactions] | High throughput | no | yes |
| CH033_HUMAN | [view interactions] | High throughput | no | yes |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| US6NL_HUMAN | [view interactions] | High throughput | no | yes |
| CAMP3_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VANG1_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| CCD34_HUMAN | [view interactions] | High throughput | no | no |
| WAPL_HUMAN | [view interactions] | High throughput | no | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| CCZ1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |
| CDKA1_HUMAN | [view interactions] | High throughput | no | yes |
| XIAP_HUMAN | [view interactions] | High throughput | no | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPA_HUMAN | [view interactions] | High throughput | no | yes |
| CEBPZ_HUMAN | [view interactions] | High throughput | no | no |
| XPR1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPU_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHSS2_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB5_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC3HD_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| ZFAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN639_HUMAN | [view interactions] | High throughput | no | yes |
| CO5A3_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| KC1G2_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CWC22_HUMAN | [view interactions] | High throughput | no | yes |
| F10C1_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP16_HUMAN | [view interactions] | High throughput | no | yes |
| AGO2_HUMAN | [view interactions] | High throughput | no | yes |
| DHX40_HUMAN | [view interactions] | High throughput | no | yes |
| ERCC5_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBED1_HUMAN | [view interactions] | High throughput | no | yes |
| DPP2_HUMAN | [view interactions] | High throughput | no | yes |
| NUCB2_HUMAN | [view interactions] | High throughput | no | yes |
| DTL_HUMAN | [view interactions] | High throughput | no | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F7_HUMAN | [view interactions] | High throughput | no | no |
| K0930_HUMAN | [view interactions] | High throughput | no | yes |
| EHD2_HUMAN | [view interactions] | High throughput | no | no |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| P3H2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| TAB1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOF1_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERC6L_HUMAN | [view interactions] | High throughput | no | yes |
| MARC2_HUMAN | [view interactions] | High throughput | no | no |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| AMERL_HUMAN | [view interactions] | High throughput | no | no |
| EVI5_HUMAN | [view interactions] | High throughput | no | yes |
| CA043_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODR4_HUMAN | [view interactions] | High throughput | no | yes |
| ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WAC2C_HUMAN | [view interactions] | High throughput | no | yes |
| S4A7_HUMAN | [view interactions] | High throughput | no | no |
| RIPR1_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FA83B_HUMAN | [view interactions] | High throughput | no | no |
| SPIN1_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF8_HUMAN | [view interactions] | High throughput | no | yes |
| CIA2B_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FBX3_HUMAN | [view interactions] | High throughput | no | no |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| FCSD2_HUMAN | [view interactions] | High throughput | no | no |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| FEZ2_HUMAN | [view interactions] | High throughput | no | yes |
| WASH1_HUMAN | [view interactions] | High throughput | no | yes |
| FNBP1_HUMAN | [view interactions] | High throughput | no | yes |
| WIPI3_HUMAN | [view interactions] | High throughput | no | no |
| FBP1L_HUMAN | [view interactions] | High throughput | no | yes |
| VPS29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXP4_HUMAN | [view interactions] | High throughput | no | yes |
| GATD1_HUMAN | [view interactions] | High throughput | no | no |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |
| GKAP1_HUMAN | [view interactions] | High throughput | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNX12_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| WASP_HUMAN | [view interactions] | Computational | no | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SORL_HUMAN | [view interactions] | Computational | no | yes |