DLG1_HUMAN
Essential multidomain scaffolding protein required for normal development . Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001310 | DEG_SCF_TRCP1_1 | DEG | 597 | 602 | - |
ELMI003253 | MOD_CDK_SPxK_1 | MOD | 155 | 161 | - |
ELMI003254 | MOD_CDK_SPxK_1 | MOD | 440 | 446 | - |
ELMI001310 | DEG_SCF_TRCP1_1 | DEG | 597 | 602 | - |
ELMI003253 | MOD_CDK_SPxK_1 | MOD | 155 | 161 | - |
ELMI003254 | MOD_CDK_SPxK_1 | MOD | 440 | 446 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in DLG1_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 32.6667 | 4 | no |
GO:0000166 | nucleotide binding | 28.0000 | 4 | no |
GO:0017076 | purine nucleotide binding | 27.3333 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 27.3333 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 26.6667 | 4 | no |
GO:0019900 | kinase binding | 22.0000 | 4 | yes |
GO:0016301 | kinase activity | 12.6667 | 4 | yes |
GO:0045296 | cadherin binding | 8.0000 | 4 | yes |
GO:0019902 | phosphatase binding | 6.6667 | 4 | yes |
GO:0016791 | phosphatase activity | 4.6667 | 5 | yes |
GO:0042578 | phosphoric ester hydrolase activity | 4.6667 | 4 | yes |
GO:0097016 | L27 domain binding | 3.3333 | 4 | yes |
GO:0099106 | ion channel regulator activity | 3.3333 | 4 | yes |
GO:0004385 | guanylate kinase activity | 2.6667 | 6 | yes |
GO:0016776 | phosphotransferase activity, phosphate group as acceptor | 2.6667 | 4 | yes |
GO:0019205 | nucleobase-containing compound kinase activity | 2.6667 | 5 | yes |
GO:0050145 | nucleoside monophosphate kinase activity | 2.6667 | 5 | yes |
GO:0098879 | structural constituent of postsynaptic specialization | 2.0000 | 4 | yes |
GO:0015459 | potassium channel regulator activity | 1.3333 | 5 | yes |
GO:0098919 | structural constituent of postsynaptic density | 1.3333 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in DLG1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 66.0000 | 4 | yes |
GO:0010646 | regulation of cell communication | 59.3333 | 4 | yes |
GO:0009966 | regulation of signal transduction | 46.0000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 44.0000 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 42.0000 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 40.6667 | 4 | yes |
GO:0008104 | protein localization | 39.3333 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 38.0000 | 4 | yes |
GO:0022607 | cellular component assembly | 37.3333 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 36.0000 | 4 | yes |
GO:0051049 | regulation of transport | 33.3333 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
GO:0010647 | positive regulation of cell communication | 33.3333 | 5 | no |
GO:0023056 | positive regulation of signaling | 33.3333 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 32.0000 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 32.0000 | 4 | no |
GO:0006996 | organelle organization | 32.0000 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 31.3333 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 30.6667 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 30.0000 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 29.3333 | 5 | no |
GO:0060341 | regulation of cellular localization | 28.6667 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 28.0000 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 27.3333 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 27.3333 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 26.6667 | 5 | yes |
GO:0009967 | positive regulation of signal transduction | 26.0000 | 5 | no |
GO:0010468 | regulation of gene expression | 26.0000 | 6 | yes |
GO:0032880 | regulation of protein localization | 24.6667 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 24.6667 | 5 | yes |
GO:0030030 | cell projection organization | 24.0000 | 4 | no |
GO:0031399 | regulation of protein modification process | 24.0000 | 6 | no |
GO:0042127 | regulation of cell population proliferation | 23.3333 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 23.3333 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 23.3333 | 6 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.6667 | 6 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.0000 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 21.3333 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 21.3333 | 4 | no |
GO:0033043 | regulation of organelle organization | 20.6667 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 20.6667 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 20.6667 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 20.6667 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.0000 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 20.0000 | 5 | yes |
GO:0023057 | negative regulation of signaling | 19.3333 | 4 | yes |
GO:0034330 | cell junction organization | 19.3333 | 4 | yes |
GO:0072657 | protein localization to membrane | 19.3333 | 4 | yes |
GO:0141124 | intracellular signaling cassette | 19.3333 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 19.3333 | 5 | yes |
GO:0007010 | cytoskeleton organization | 18.6667 | 5 | yes |
GO:0099536 | synaptic signaling | 18.0000 | 4 | yes |
GO:0099537 | trans-synaptic signaling | 18.0000 | 5 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 17.3333 | 5 | yes |
GO:0043933 | protein-containing complex organization | 17.3333 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 17.3333 | 4 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 17.3333 | 6 | yes |
GO:0007268 | chemical synaptic transmission | 17.3333 | 7 | yes |
GO:0030155 | regulation of cell adhesion | 16.6667 | 4 | yes |
GO:0043269 | regulation of monoatomic ion transport | 16.6667 | 5 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 16.6667 | 4 | yes |
GO:1903829 | positive regulation of protein localization | 16.6667 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 16.0000 | 5 | yes |
GO:0044057 | regulation of system process | 16.0000 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 16.0000 | 5 | yes |
GO:0051050 | positive regulation of transport | 15.3333 | 4 | yes |
GO:0051960 | regulation of nervous system development | 15.3333 | 5 | yes |
GO:0065003 | protein-containing complex assembly | 15.3333 | 5 | yes |
GO:0008284 | positive regulation of cell population proliferation | 15.3333 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 14.6667 | 4 | yes |
GO:0051252 | regulation of RNA metabolic process | 14.6667 | 5 | yes |
GO:0034329 | cell junction assembly | 14.0000 | 5 | yes |
GO:0043408 | regulation of MAPK cascade | 14.0000 | 6 | yes |
GO:1990778 | protein localization to cell periphery | 14.0000 | 5 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 14.0000 | 6 | yes |
GO:0006355 | regulation of DNA-templated transcription | 14.0000 | 7 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 13.3333 | 5 | yes |
GO:0051493 | regulation of cytoskeleton organization | 13.3333 | 6 | yes |
GO:0061024 | membrane organization | 13.3333 | 4 | yes |
GO:1905475 | regulation of protein localization to membrane | 13.3333 | 6 | yes |
GO:0034765 | regulation of monoatomic ion transmembrane transport | 12.6667 | 5 | yes |
GO:0051726 | regulation of cell cycle | 12.6667 | 4 | yes |
GO:0009890 | negative regulation of biosynthetic process | 12.6667 | 5 | yes |
GO:0031327 | negative regulation of cellular biosynthetic process | 12.0000 | 6 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 12.0000 | 6 | yes |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 12.0000 | 6 | yes |
GO:0033365 | protein localization to organelle | 11.3333 | 5 | yes |
GO:0097435 | supramolecular fiber organization | 11.3333 | 4 | yes |
GO:0008285 | negative regulation of cell population proliferation | 11.3333 | 5 | yes |
GO:0010959 | regulation of metal ion transport | 11.3333 | 6 | yes |
GO:0032970 | regulation of actin filament-based process | 10.6667 | 4 | yes |
GO:1902903 | regulation of supramolecular fiber organization | 10.6667 | 5 | yes |
GO:1904062 | regulation of monoatomic cation transmembrane transport | 10.6667 | 6 | yes |
GO:0010638 | positive regulation of organelle organization | 10.6667 | 6 | yes |
GO:0032956 | regulation of actin cytoskeleton organization | 10.0000 | 5 | yes |
GO:0045216 | cell-cell junction organization | 10.0000 | 5 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 10.0000 | 6 | yes |
GO:1905477 | positive regulation of protein localization to membrane | 10.0000 | 6 | yes |
GO:0010564 | regulation of cell cycle process | 10.0000 | 5 | yes |
GO:0032535 | regulation of cellular component size | 9.3333 | 4 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 9.3333 | 6 | yes |
GO:0022407 | regulation of cell-cell adhesion | 8.6667 | 5 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 8.6667 | 8 | yes |
GO:0007015 | actin filament organization | 8.6667 | 5 | yes |
GO:0035418 | protein localization to synapse | 8.0000 | 6 | yes |
GO:0051495 | positive regulation of cytoskeleton organization | 8.0000 | 7 | yes |
GO:0110053 | regulation of actin filament organization | 8.0000 | 6 | yes |
GO:1902414 | protein localization to cell junction | 8.0000 | 5 | yes |
GO:0007043 | cell-cell junction assembly | 8.0000 | 6 | yes |
GO:0022604 | regulation of cell morphogenesis | 7.3333 | 5 | yes |
GO:0035088 | establishment or maintenance of apical/basal cell polarity | 7.3333 | 4 | yes |
GO:0043113 | receptor clustering | 7.3333 | 5 | yes |
GO:0043270 | positive regulation of monoatomic ion transport | 7.3333 | 5 | yes |
GO:0050863 | regulation of T cell activation | 7.3333 | 6 | yes |
GO:0050865 | regulation of cell activation | 7.3333 | 4 | yes |
GO:0051249 | regulation of lymphocyte activation | 7.3333 | 5 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 7.3333 | 7 | yes |
GO:1902905 | positive regulation of supramolecular fiber organization | 7.3333 | 6 | yes |
GO:1903076 | regulation of protein localization to plasma membrane | 7.3333 | 7 | yes |
GO:0002009 | morphogenesis of an epithelium | 7.3333 | 4 | yes |
GO:0002694 | regulation of leukocyte activation | 7.3333 | 4 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 6.6667 | 5 | yes |
GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 6.6667 | 5 | yes |
GO:0072659 | protein localization to plasma membrane | 6.6667 | 5 | yes |
GO:1903078 | positive regulation of protein localization to plasma membrane | 6.6667 | 7 | yes |
GO:0007162 | negative regulation of cell adhesion | 6.6667 | 5 | yes |
GO:0030865 | cortical cytoskeleton organization | 6.0000 | 6 | yes |
GO:0051896 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 6.0000 | 6 | yes |
GO:0062237 | protein localization to postsynapse | 6.0000 | 7 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 6.0000 | 6 | yes |
GO:1903522 | regulation of blood circulation | 6.0000 | 5 | yes |
GO:1903539 | protein localization to postsynaptic membrane | 6.0000 | 5 | yes |
GO:0007346 | regulation of mitotic cell cycle | 6.0000 | 5 | yes |
GO:0022898 | regulation of transmembrane transporter activity | 5.3333 | 4 | yes |
GO:0031334 | positive regulation of protein-containing complex assembly | 5.3333 | 6 | yes |
GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 5.3333 | 5 | yes |
GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 5.3333 | 5 | yes |
GO:0050678 | regulation of epithelial cell proliferation | 5.3333 | 5 | yes |
GO:0051253 | negative regulation of RNA metabolic process | 5.3333 | 6 | yes |
GO:1901987 | regulation of cell cycle phase transition | 5.3333 | 6 | yes |
GO:0002683 | negative regulation of immune system process | 5.3333 | 4 | yes |
GO:0032271 | regulation of protein polymerization | 4.6667 | 6 | yes |
GO:0032273 | positive regulation of protein polymerization | 4.6667 | 7 | yes |
GO:0043266 | regulation of potassium ion transport | 4.6667 | 7 | yes |
GO:0043409 | negative regulation of MAPK cascade | 4.6667 | 7 | yes |
GO:0045786 | negative regulation of cell cycle | 4.6667 | 5 | yes |
GO:0045892 | negative regulation of DNA-templated transcription | 4.6667 | 8 | yes |
GO:1901990 | regulation of mitotic cell cycle phase transition | 4.6667 | 6 | yes |
GO:1902679 | negative regulation of RNA biosynthetic process | 4.6667 | 7 | yes |
GO:0000122 | negative regulation of transcription by RNA polymerase II | 4.6667 | 9 | yes |
GO:0008016 | regulation of heart contraction | 4.6667 | 6 | yes |
GO:0030832 | regulation of actin filament length | 4.0000 | 5 | yes |
GO:0030866 | cortical actin cytoskeleton organization | 4.0000 | 4 | yes |
GO:0031122 | cytoplasmic microtubule organization | 4.0000 | 4 | yes |
GO:0032944 | regulation of mononuclear cell proliferation | 4.0000 | 6 | yes |
GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | 4.0000 | 5 | yes |
GO:0045930 | negative regulation of mitotic cell cycle | 4.0000 | 6 | yes |
GO:0050670 | regulation of lymphocyte proliferation | 4.0000 | 6 | yes |
GO:0070373 | negative regulation of ERK1 and ERK2 cascade | 4.0000 | 8 | yes |
GO:0070663 | regulation of leukocyte proliferation | 4.0000 | 5 | yes |
GO:0099633 | protein localization to postsynaptic specialization membrane | 4.0000 | 6 | yes |
GO:0099645 | neurotransmitter receptor localization to postsynaptic specialization membrane | 4.0000 | 4 | yes |
GO:1901379 | regulation of potassium ion transmembrane transport | 4.0000 | 7 | yes |
GO:1902806 | regulation of cell cycle G1/S phase transition | 4.0000 | 7 | yes |
GO:0008064 | regulation of actin polymerization or depolymerization | 4.0000 | 6 | yes |
GO:0042110 | T cell activation | 3.3333 | 4 | yes |
GO:0042129 | regulation of T cell proliferation | 3.3333 | 7 | yes |
GO:0043268 | positive regulation of potassium ion transport | 3.3333 | 6 | yes |
GO:0051258 | protein polymerization | 3.3333 | 6 | yes |
GO:0060537 | muscle tissue development | 3.3333 | 4 | yes |
GO:0090257 | regulation of muscle system process | 3.3333 | 5 | yes |
GO:1901988 | negative regulation of cell cycle phase transition | 3.3333 | 7 | yes |
GO:1901991 | negative regulation of mitotic cell cycle phase transition | 3.3333 | 7 | yes |
GO:1902473 | regulation of protein localization to synapse | 3.3333 | 6 | yes |
GO:1902807 | negative regulation of cell cycle G1/S phase transition | 3.3333 | 8 | yes |
GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 3.3333 | 7 | yes |
GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 3.3333 | 8 | yes |
GO:2001257 | regulation of cation channel activity | 3.3333 | 6 | yes |
GO:0006936 | muscle contraction | 3.3333 | 4 | yes |
GO:0010948 | negative regulation of cell cycle process | 3.3333 | 6 | yes |
GO:0022408 | negative regulation of cell-cell adhesion | 2.6667 | 6 | yes |
GO:0030833 | regulation of actin filament polymerization | 2.6667 | 7 | yes |
GO:0030838 | positive regulation of actin filament polymerization | 2.6667 | 7 | yes |
GO:0030953 | astral microtubule organization | 2.6667 | 4 | yes |
GO:0031641 | regulation of myelination | 2.6667 | 4 | yes |
GO:0032945 | negative regulation of mononuclear cell proliferation | 2.6667 | 7 | yes |
GO:0048754 | branching morphogenesis of an epithelial tube | 2.6667 | 4 | yes |
GO:0050672 | negative regulation of lymphocyte proliferation | 2.6667 | 7 | yes |
GO:0050680 | negative regulation of epithelial cell proliferation | 2.6667 | 6 | yes |
GO:0050866 | negative regulation of cell activation | 2.6667 | 5 | yes |
GO:0051250 | negative regulation of lymphocyte activation | 2.6667 | 6 | yes |
GO:0070664 | negative regulation of leukocyte proliferation | 2.6667 | 6 | yes |
GO:0070830 | bicellular tight junction assembly | 2.6667 | 8 | yes |
GO:0120192 | tight junction assembly | 2.6667 | 7 | yes |
GO:0120193 | tight junction organization | 2.6667 | 6 | yes |
GO:1900744 | regulation of p38MAPK cascade | 2.6667 | 7 | yes |
GO:1903753 | negative regulation of p38MAPK cascade | 2.6667 | 8 | yes |
GO:0002695 | negative regulation of leukocyte activation | 2.6667 | 5 | yes |
GO:0006937 | regulation of muscle contraction | 2.6667 | 6 | yes |
GO:0006939 | smooth muscle contraction | 2.6667 | 5 | yes |
GO:0008154 | actin polymerization or depolymerization | 2.6667 | 6 | yes |
GO:0030041 | actin filament polymerization | 2.0000 | 7 | yes |
GO:0031579 | membrane raft organization | 2.0000 | 5 | yes |
GO:0032943 | mononuclear cell proliferation | 2.0000 | 4 | yes |
GO:0042098 | T cell proliferation | 2.0000 | 5 | yes |
GO:0042130 | negative regulation of T cell proliferation | 2.0000 | 8 | yes |
GO:0042982 | amyloid precursor protein metabolic process | 2.0000 | 4 | yes |
GO:0043622 | cortical microtubule organization | 2.0000 | 5 | yes |
GO:0046651 | lymphocyte proliferation | 2.0000 | 4 | yes |
GO:0048562 | embryonic organ morphogenesis | 2.0000 | 4 | yes |
GO:0048704 | embryonic skeletal system morphogenesis | 2.0000 | 5 | yes |
GO:0048705 | skeletal system morphogenesis | 2.0000 | 4 | yes |
GO:0050868 | negative regulation of T cell activation | 2.0000 | 7 | yes |
GO:0051660 | establishment of centrosome localization | 2.0000 | 4 | yes |
GO:0051898 | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 2.0000 | 7 | yes |
GO:0055117 | regulation of cardiac muscle contraction | 2.0000 | 7 | yes |
GO:0086004 | regulation of cardiac muscle cell contraction | 2.0000 | 6 | yes |
GO:1901016 | regulation of potassium ion transmembrane transporter activity | 2.0000 | 6 | yes |
GO:1902305 | regulation of sodium ion transmembrane transport | 2.0000 | 7 | yes |
GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 2.0000 | 7 | yes |
GO:1903115 | regulation of actin filament-based movement | 2.0000 | 5 | yes |
GO:0001658 | branching involved in ureteric bud morphogenesis | 2.0000 | 5 | yes |
GO:0002028 | regulation of sodium ion transport | 2.0000 | 7 | yes |
GO:0006942 | regulation of striated muscle contraction | 2.0000 | 7 | yes |
GO:0030432 | peristalsis | 1.3333 | 7 | yes |
GO:0048745 | smooth muscle tissue development | 1.3333 | 5 | yes |
GO:0098901 | regulation of cardiac muscle cell action potential | 1.3333 | 4 | yes |
GO:0098911 | regulation of ventricular cardiac muscle cell action potential | 1.3333 | 5 | yes |
GO:1903286 | regulation of potassium ion import | 1.3333 | 8 | yes |
GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | 1.3333 | 7 | yes |
GO:1903764 | regulation of potassium ion export across plasma membrane | 1.3333 | 8 | yes |
GO:0001771 | immunological synapse formation | 1.3333 | 4 | yes |
GO:0001935 | endothelial cell proliferation | 1.3333 | 4 | yes |
GO:0014821 | phasic smooth muscle contraction | 1.3333 | 6 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
ERBB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KIF1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ANO9_HUMAN | [view interactions] | Low throughput | no | yes |
ARHG8_HUMAN | [view interactions] | Low throughput | no | yes |
CLTR2_HUMAN | [view interactions] | Low throughput | no | no |
CRIPT_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AGRA2_HUMAN | [view interactions] | Low throughput | no | no |
KCNA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCJ12_HUMAN | [view interactions] | Low throughput | no | no |
ADA10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ADRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TOPK_HUMAN | [view interactions] | Low throughput | no | no |
LRFN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRFN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AT2B2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DGKZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MP2K2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHSA9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DSCAM_HUMAN | [view interactions] | Low throughput | no | yes |
IQEC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRID2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRIA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSMD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ADA17_HUMAN | [view interactions] | Low throughput | no | yes |
TANC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRP4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GPSM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SCN7A_HUMAN | [view interactions] | Low throughput | no | no |
FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
CRFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MAP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LCK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KCNJ2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNJ4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GCYA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NRCAM_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DGKI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KI13B_HUMAN | [view interactions] | Low throughput | no | yes |
DLG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RL40_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK12_HUMAN | [view interactions] | Low throughput | no | no |
APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNJ6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CRCM_HUMAN | [view interactions] | Low throughput | no | no |
KS6A2_HUMAN | [view interactions] | Low throughput | no | yes |
TANC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IQEC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TJAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRRC1_HUMAN | [view interactions] | Low throughput | no | yes |
TGFA_HUMAN | [view interactions] | Low throughput | no | yes |
KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ACTN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRIK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MPP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARH2_HUMAN | [view interactions] | Low throughput | no | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK14_HUMAN | [view interactions] | Low throughput | no | yes |
CAV3_HUMAN | [view interactions] | Low throughput | no | no |
5HT2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SSR1_HUMAN | [view interactions] | Low throughput | no | no |
GBG13_HUMAN | [view interactions] | Low throughput | no | no |
EPB41_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AT2B4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBE3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CXB1_HUMAN | [view interactions] | Low throughput | no | yes |
DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNA5_HUMAN | [view interactions] | Low throughput | no | no |
SCN5A_HUMAN | [view interactions] | Low throughput | no | no |
NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ZSC30_HUMAN | [view interactions] | High throughput | no | yes |
FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PL8L1_HUMAN | [view interactions] | High throughput | no | no |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXD3_HUMAN | [view interactions] | High throughput | no | no |
DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
F163A_HUMAN | [view interactions] | High throughput | no | no |
LAMP3_HUMAN | [view interactions] | High throughput | no | no |
MARH3_HUMAN | [view interactions] | High throughput | no | no |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F163B_HUMAN | [view interactions] | High throughput | no | yes |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
TBX15_HUMAN | [view interactions] | High throughput | no | yes |
RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGRA3_HUMAN | [view interactions] | High throughput | no | yes |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STX6_HUMAN | [view interactions] | High throughput | no | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
DLGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UFO_HUMAN | [view interactions] | High throughput | no | no |
DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
AR13B_HUMAN | [view interactions] | High throughput | no | yes |
ARL14_HUMAN | [view interactions] | High throughput | no | no |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
RAB25_HUMAN | [view interactions] | High throughput | no | no |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHSA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZMYM1_HUMAN | [view interactions] | High throughput | no | no |
RN146_HUMAN | [view interactions] | High throughput | no | yes |
ARHGG_HUMAN | [view interactions] | High throughput | no | yes |
ARHGQ_HUMAN | [view interactions] | High throughput | no | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
PTHD1_HUMAN | [view interactions] | High throughput | no | no |
ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
P85A_HUMAN | [view interactions] | High throughput | no | yes |
CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
FZD1_HUMAN | [view interactions] | High throughput | no | yes |
FZD4_HUMAN | [view interactions] | High throughput | no | yes |
FZD7_HUMAN | [view interactions] | High throughput | no | yes |
M3K3_HUMAN | [view interactions] | High throughput | no | no |
MAS_HUMAN | [view interactions] | High throughput | no | no |
ADA1D_HUMAN | [view interactions] | High throughput | no | no |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
UBS3A_HUMAN | [view interactions] | High throughput | no | no |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTPRE_HUMAN | [view interactions] | High throughput | no | no |
EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EPHA5_HUMAN | [view interactions] | High throughput | no | no |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZSWM7_HUMAN | [view interactions] | High throughput | no | no |
SWAP1_HUMAN | [view interactions] | High throughput | no | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ANO2_HUMAN | [view interactions] | High throughput | no | no |
NMDE3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EVI5_HUMAN | [view interactions] | High throughput | no | yes |
S14L3_HUMAN | [view interactions] | High throughput | no | no |
CAHM3_HUMAN | [view interactions] | High throughput | no | no |
VANG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MOT4_HUMAN | [view interactions] | High throughput | no | yes |
VANG1_HUMAN | [view interactions] | High throughput | no | no |
HTR5B_HUMAN | [view interactions] | High throughput | no | yes |
MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
RAPSN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NMDE4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRR3C_HUMAN | [view interactions] | High throughput | no | no |
PABP2_HUMAN | [view interactions] | High throughput | no | yes |
CD1D_HUMAN | [view interactions] | High throughput | no | yes |
T178A_HUMAN | [view interactions] | High throughput | no | no |
KCJ18_HUMAN | [view interactions] | High throughput | no | no |
EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
5HT2C_HUMAN | [view interactions] | High throughput | no | no |
TPBGL_HUMAN | [view interactions] | High throughput | no | no |
SSBP2_HUMAN | [view interactions] | High throughput | no | yes |
RT34_HUMAN | [view interactions] | High throughput | no | yes |
DB116_HUMAN | [view interactions] | High throughput | no | no |
LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APBA1_HUMAN | [view interactions] | High throughput | no | no |
CBL_HUMAN | [view interactions] | High throughput | no | yes |
ZAP70_HUMAN | [view interactions] | High throughput | no | no |
WASP_HUMAN | [view interactions] | High throughput | no | yes |
HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
KI26B_HUMAN | [view interactions] | High throughput | no | yes |
MPP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFNB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXB7_HUMAN | [view interactions] | High throughput | no | no |
PRDM1_HUMAN | [view interactions] | High throughput | no | yes |
GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIBRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
R144A_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DUS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTMR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTBP2_HUMAN | [view interactions] | High throughput | no | no |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
MAFB_HUMAN | [view interactions] | High throughput | no | yes |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FA20C_HUMAN | [view interactions] | High throughput | no | no |
MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
COPT1_HUMAN | [view interactions] | High throughput | no | no |
SPAT2_HUMAN | [view interactions] | High throughput | no | yes |
LIN7B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EFC11_HUMAN | [view interactions] | High throughput | no | no |
TULP4_HUMAN | [view interactions] | High throughput | no | yes |
ATS1_HUMAN | [view interactions] | High throughput | no | no |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
RHOU_HUMAN | [view interactions] | High throughput | no | no |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
RND2_HUMAN | [view interactions] | High throughput | no | no |
RND3_HUMAN | [view interactions] | High throughput | no | no |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
RHOD_HUMAN | [view interactions] | High throughput | no | no |
RHOV_HUMAN | [view interactions] | High throughput | no | no |
RND1_HUMAN | [view interactions] | High throughput | no | no |
LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
SRP09_HUMAN | [view interactions] | High throughput | no | no |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLD4_HUMAN | [view interactions] | High throughput | no | yes |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MIDN_HUMAN | [view interactions] | High throughput | no | no |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
CSK_HUMAN | [view interactions] | High throughput | no | yes |
KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
AGRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CADM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PI42B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PALS2_HUMAN | [view interactions] | High throughput | no | yes |
GCYB1_HUMAN | [view interactions] | High throughput | no | yes |
KCJ10_HUMAN | [view interactions] | High throughput | no | no |
BGAL_HUMAN | [view interactions] | High throughput | no | yes |
IRS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CARL1_HUMAN | [view interactions] | High throughput | no | yes |
PRRC1_HUMAN | [view interactions] | High throughput | no | yes |
NUP50_HUMAN | [view interactions] | High throughput | no | yes |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NXPE2_HUMAN | [view interactions] | High throughput | no | no |
DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASF6_HUMAN | [view interactions] | High throughput | no | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRPD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
SO1C1_HUMAN | [view interactions] | High throughput | no | no |
CK052_HUMAN | [view interactions] | High throughput | no | no |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRR5_HUMAN | [view interactions] | High throughput | no | yes |
CXAR_HUMAN | [view interactions] | High throughput | no | yes |
RNF12_HUMAN | [view interactions] | High throughput | no | yes |
DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41LA_HUMAN | [view interactions] | High throughput | no | yes |