Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DLG1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Essential multidomain scaffolding protein required for normal development . Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI001310 DEG_SCF_TRCP1_1 DEG 597 602 -
ELMI003253 MOD_CDK_SPxK_1 MOD 155 161 -
ELMI003254 MOD_CDK_SPxK_1 MOD 440 446 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DLG1_HUMAN
GO:0017076 purine nucleotide binding 27.1523 4 no
GO:0032555 purine ribonucleotide binding 27.1523 4 no
GO:0035639 purine ribonucleoside triphosphate binding 26.4901 4 no
GO:0019900 kinase binding 23.1788 4 yes
GO:0019901 protein kinase binding 21.1921 5 yes
GO:0016301 kinase activity 13.9073 4 yes
GO:0045296 cadherin binding 9.2715 4 yes
GO:0019902 phosphatase binding 6.6225 4 yes
GO:0016791 phosphatase activity 4.6358 5 yes
GO:0042578 phosphoric ester hydrolase activity 4.6358 4 yes
GO:0097016 L27 domain binding 3.3113 4 yes
GO:0004385 guanylate kinase activity 2.6490 6 yes
GO:0016776 phosphotransferase activity, phosphate group as acceptor 2.6490 4 yes
GO:0019205 nucleobase-containing compound kinase activity 2.6490 5 yes
GO:0050145 nucleoside monophosphate kinase activity 2.6490 5 yes
GO:0015459 potassium channel regulator activity 1.9868 4 yes
GO:0098879 structural constituent of postsynaptic specialization 1.9868 4 yes
GO:0098919 structural constituent of postsynaptic density 1.9868 5 yes
GO:0031434 mitogen-activated protein kinase kinase binding 1.3245 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DLG1_HUMAN
GO:0048522 positive regulation of cellular process 64.9007 4 yes
GO:0010646 regulation of cell communication 59.6026 4 yes
GO:0009966 regulation of signal transduction 46.3576 4 yes
GO:0051128 regulation of cellular component organization 41.7219 4 yes
GO:0051049 regulation of transport 39.7351 4 yes
GO:0060255 regulation of macromolecule metabolic process 39.0728 4 yes
GO:0008104 protein localization 39.0728 4 yes
GO:0048523 negative regulation of cellular process 38.4106 4 yes
GO:0050804 modulation of chemical synaptic transmission 36.4238 5 no
GO:0099177 regulation of trans-synaptic signaling 36.4238 4 no
GO:0022607 cellular component assembly 36.4238 4 yes
GO:0080090 regulation of primary metabolic process 35.7616 4 yes
GO:0009893 positive regulation of metabolic process 35.0993 4 yes
GO:0031323 regulation of cellular metabolic process 34.4371 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 33.1126 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 32.4503 5 yes
GO:0023056 positive regulation of signaling 31.1258 4 no
GO:0006996 organelle organization 31.1258 4 yes
GO:0010647 positive regulation of cell communication 30.4636 5 no
GO:0051246 regulation of protein metabolic process 29.8013 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 29.1391 5 yes
GO:0031325 positive regulation of cellular metabolic process 27.8146 5 yes
GO:0060341 regulation of cellular localization 26.4901 4 yes
GO:1902531 regulation of intracellular signal transduction 26.4901 5 yes
GO:0030030 cell projection organization 26.4901 4 no
GO:0051247 positive regulation of protein metabolic process 25.8278 6 yes
GO:0043085 positive regulation of catalytic activity 24.5033 4 yes
GO:0051174 regulation of phosphorus metabolic process 24.5033 5 yes
GO:0048584 positive regulation of response to stimulus 24.5033 4 no
GO:0019220 regulation of phosphate metabolic process 24.5033 6 yes
GO:0032880 regulation of protein localization 23.8411 5 yes
GO:0042325 regulation of phosphorylation 23.8411 7 yes
GO:0016192 vesicle-mediated transport 23.8411 4 no
GO:0031399 regulation of protein modification process 23.8411 6 yes
GO:0010468 regulation of gene expression 23.1788 5 yes
GO:0051130 positive regulation of cellular component organization 22.5166 5 yes
GO:0071702 organic substance transport 22.5166 4 no
GO:0120036 plasma membrane bounded cell projection organization 22.5166 5 no
GO:0010941 regulation of cell death 22.5166 4 no
GO:0042127 regulation of cell population proliferation 21.8543 4 yes
GO:0043269 regulation of ion transport 21.8543 5 yes
GO:0001932 regulation of protein phosphorylation 21.8543 7 yes
GO:0071705 nitrogen compound transport 21.1921 4 no
GO:0031344 regulation of cell projection organization 21.1921 5 no
GO:0042981 regulation of apoptotic process 21.1921 6 no
GO:0043067 regulation of programmed cell death 21.1921 5 no
GO:0031401 positive regulation of protein modification process 21.1921 7 yes
GO:0033043 regulation of organelle organization 20.5298 5 yes
GO:0009967 positive regulation of signal transduction 20.5298 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 20.5298 6 no
GO:0007010 cytoskeleton organization 20.5298 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 20.5298 4 yes
GO:0042327 positive regulation of phosphorylation 19.8675 8 yes
GO:0045937 positive regulation of phosphate metabolic process 19.8675 7 yes
GO:0051050 positive regulation of transport 19.8675 4 yes
GO:0072657 protein localization to membrane 19.8675 4 yes
GO:0009892 negative regulation of metabolic process 19.8675 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 19.8675 6 yes
GO:0010648 negative regulation of cell communication 19.8675 5 yes
GO:0023057 negative regulation of signaling 19.8675 4 yes
GO:0034330 cell junction organization 19.2053 4 yes
GO:0044057 regulation of system process 19.2053 4 yes
GO:0044087 regulation of cellular component biogenesis 18.5430 4 yes
GO:0051338 regulation of transferase activity 18.5430 4 yes
GO:2000026 regulation of multicellular organismal development 18.5430 4 yes
GO:0001934 positive regulation of protein phosphorylation 18.5430 8 yes
GO:0010605 negative regulation of macromolecule metabolic process 18.5430 5 yes
GO:0043549 regulation of kinase activity 17.8808 5 yes
GO:0099537 trans-synaptic signaling 17.8808 4 yes
GO:0030155 regulation of cell adhesion 17.8808 4 yes
GO:0098916 anterograde trans-synaptic signaling 17.2185 5 yes
GO:0007268 chemical synaptic transmission 17.2185 6 yes
GO:0034762 regulation of transmembrane transport 16.5563 4 yes
GO:0034765 regulation of ion transmembrane transport 16.5563 5 yes
GO:1903829 positive regulation of protein localization 16.5563 5 yes
GO:0009889 regulation of biosynthetic process 16.5563 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 16.5563 5 yes
GO:0048585 negative regulation of response to stimulus 15.8940 4 yes
GO:0051347 positive regulation of transferase activity 15.8940 5 yes
GO:0031326 regulation of cellular biosynthetic process 15.8940 5 yes
GO:0033674 positive regulation of kinase activity 14.5695 6 yes
GO:0043408 regulation of MAPK cascade 14.5695 6 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 14.5695 5 yes
GO:0051252 regulation of RNA metabolic process 14.5695 5 yes
GO:1905475 regulation of protein localization to membrane 14.5695 6 yes
GO:1990778 protein localization to cell periphery 14.5695 5 yes
GO:0008284 positive regulation of cell population proliferation 14.5695 5 yes
GO:0009968 negative regulation of signal transduction 14.5695 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 14.5695 5 yes
GO:0034329 cell junction assembly 13.9073 5 yes
GO:0045859 regulation of protein kinase activity 13.9073 6 yes
GO:0051960 regulation of nervous system development 13.9073 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 13.9073 7 yes
GO:2001141 regulation of RNA biosynthetic process 13.9073 6 yes
GO:0006355 regulation of DNA-templated transcription 13.9073 6 yes
GO:0031324 negative regulation of cellular metabolic process 13.9073 5 yes
GO:0051493 regulation of cytoskeleton organization 13.2450 6 yes
GO:0080134 regulation of response to stress 13.2450 4 yes
GO:0032970 regulation of actin filament-based process 12.5828 4 yes
GO:0044089 positive regulation of cellular component biogenesis 12.5828 5 yes
GO:0061024 membrane organization 12.5828 4 yes
GO:0097435 supramolecular fiber organization 12.5828 4 yes
GO:1904062 regulation of cation transmembrane transport 12.5828 6 yes
GO:0032956 regulation of actin cytoskeleton organization 11.9205 5 yes
GO:1904375 regulation of protein localization to cell periphery 11.9205 6 yes
GO:0033365 protein localization to organelle 11.2583 5 yes
GO:0045860 positive regulation of protein kinase activity 11.2583 7 yes
GO:0051726 regulation of cell cycle 11.2583 4 yes
GO:0008285 negative regulation of cell population proliferation 11.2583 5 yes
GO:0045216 cell-cell junction organization 10.5960 5 yes
GO:0007015 actin filament organization 10.5960 5 yes
GO:0010638 positive regulation of organelle organization 10.5960 6 yes
GO:0010959 regulation of metal ion transport 10.5960 6 yes
GO:0022604 regulation of cell morphogenesis 10.5960 5 yes
GO:0050865 regulation of cell activation 9.9338 4 yes
GO:0080135 regulation of cellular response to stress 9.9338 4 yes
GO:1905477 positive regulation of protein localization to membrane 9.9338 6 yes
GO:0002694 regulation of leukocyte activation 9.9338 4 yes
GO:0022407 regulation of cell-cell adhesion 9.9338 5 yes
GO:0050863 regulation of T cell activation 9.2715 6 yes
GO:0051249 regulation of lymphocyte activation 9.2715 5 yes
GO:1902414 protein localization to cell junction 9.2715 5 yes
GO:1902903 regulation of supramolecular fiber organization 9.2715 5 yes
GO:0022898 regulation of transmembrane transporter activity 9.2715 4 yes
GO:0030865 cortical cytoskeleton organization 9.2715 6 yes
GO:0032412 regulation of ion transmembrane transporter activity 9.2715 5 yes
GO:0032535 regulation of cellular component size 8.6093 4 yes
GO:0035418 protein localization to synapse 8.6093 6 yes
GO:0043113 receptor clustering 8.6093 5 yes
GO:0043270 positive regulation of ion transport 8.6093 5 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 8.6093 7 yes
GO:1902532 negative regulation of intracellular signal transduction 8.6093 6 yes
GO:1904377 positive regulation of protein localization to cell periphery 8.6093 6 yes
GO:2001257 regulation of cation channel activity 8.6093 6 yes
GO:0110053 regulation of actin filament organization 7.9470 6 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 7.9470 6 yes
GO:0002009 morphogenesis of an epithelium 7.9470 4 yes
GO:0007162 negative regulation of cell adhesion 7.9470 5 yes
GO:0010564 regulation of cell cycle process 7.9470 5 yes
GO:0035088 establishment or maintenance of apical/basal cell polarity 7.2848 4 yes
GO:0043254 regulation of protein-containing complex assembly 7.2848 5 yes
GO:0070302 regulation of stress-activated protein kinase signaling cascade 7.2848 5 yes
GO:1903076 regulation of protein localization to plasma membrane 7.2848 7 yes
GO:0006357 regulation of transcription by RNA polymerase II 7.2848 7 yes
GO:0007043 cell-cell junction assembly 7.2848 6 yes
GO:0008360 regulation of cell shape 7.2848 6 yes
GO:0032872 regulation of stress-activated MAPK cascade 6.6225 6 yes
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 6.6225 5 yes
GO:0051495 positive regulation of cytoskeleton organization 6.6225 7 yes
GO:0062237 protein localization to postsynapse 6.6225 7 yes
GO:0072659 protein localization to plasma membrane 6.6225 5 yes
GO:1903078 positive regulation of protein localization to plasma membrane 6.6225 7 yes
GO:1903522 regulation of blood circulation 6.6225 5 yes
GO:1903539 protein localization to postsynaptic membrane 6.6225 5 yes
GO:0002683 negative regulation of immune system process 6.6225 4 yes
GO:0007346 regulation of mitotic cell cycle 6.6225 5 yes
GO:0050678 regulation of epithelial cell proliferation 5.9603 5 yes
GO:0009890 negative regulation of biosynthetic process 5.9603 5 yes
GO:0031334 positive regulation of protein-containing complex assembly 5.9603 6 yes
GO:0043409 negative regulation of MAPK cascade 5.2980 7 yes
GO:0045786 negative regulation of cell cycle 5.2980 5 yes
GO:1901987 regulation of cell cycle phase transition 5.2980 6 yes
GO:1902905 positive regulation of supramolecular fiber organization 5.2980 6 yes
GO:0008016 regulation of heart contraction 5.2980 6 yes
GO:0030866 cortical actin cytoskeleton organization 5.2980 4 yes
GO:0031327 negative regulation of cellular biosynthetic process 5.2980 6 yes
GO:0032944 regulation of mononuclear cell proliferation 4.6358 6 yes
GO:0043266 regulation of potassium ion transport 4.6358 7 yes
GO:0045930 negative regulation of mitotic cell cycle 4.6358 6 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 4.6358 6 yes
GO:0050670 regulation of lymphocyte proliferation 4.6358 6 yes
GO:0051253 negative regulation of RNA metabolic process 4.6358 6 yes
GO:0070373 negative regulation of ERK1 and ERK2 cascade 4.6358 8 yes
GO:0070663 regulation of leukocyte proliferation 4.6358 5 yes
GO:1901990 regulation of mitotic cell cycle phase transition 4.6358 6 yes
GO:0008064 regulation of actin polymerization or depolymerization 4.6358 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 4.6358 6 yes
GO:0030832 regulation of actin filament length 4.6358 5 yes
GO:0032147 activation of protein kinase activity 4.6358 8 yes
GO:0042129 regulation of T cell proliferation 3.9735 7 yes
GO:0045892 negative regulation of DNA-templated transcription 3.9735 7 yes
GO:0051896 regulation of protein kinase B signaling 3.9735 6 yes
GO:0060537 muscle tissue development 3.9735 4 yes
GO:1901379 regulation of potassium ion transmembrane transport 3.9735 7 yes
GO:1902473 regulation of protein localization to synapse 3.9735 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 3.9735 7 yes
GO:1902806 regulation of cell cycle G1/S phase transition 3.9735 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 3.9735 8 yes
GO:0006936 muscle contraction 3.9735 4 yes
GO:0031122 cytoplasmic microtubule organization 3.9735 4 yes
GO:0032271 regulation of protein polymerization 3.9735 6 yes
GO:0032273 positive regulation of protein polymerization 3.9735 7 yes
GO:0032873 negative regulation of stress-activated MAPK cascade 3.3113 7 yes
GO:0032945 negative regulation of mononuclear cell proliferation 3.3113 7 yes
GO:0042110 T cell activation 3.3113 4 yes
GO:0043268 positive regulation of potassium ion transport 3.3113 6 yes
GO:0048754 branching morphogenesis of an epithelial tube 3.3113 4 yes
GO:0050672 negative regulation of lymphocyte proliferation 3.3113 7 yes
GO:0050680 negative regulation of epithelial cell proliferation 3.3113 6 yes
GO:0050866 negative regulation of cell activation 3.3113 5 yes
GO:0051250 negative regulation of lymphocyte activation 3.3113 6 yes
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3.3113 6 yes
GO:0070664 negative regulation of leukocyte proliferation 3.3113 6 yes
GO:0090257 regulation of muscle system process 3.3113 5 yes
GO:0099633 protein localization to postsynaptic specialization membrane 3.3113 6 yes
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 3.3113 4 yes
GO:1901988 negative regulation of cell cycle phase transition 3.3113 7 yes
GO:1901991 negative regulation of mitotic cell cycle phase transition 3.3113 7 yes
GO:1902807 negative regulation of cell cycle G1/S phase transition 3.3113 8 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 3.3113 7 yes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3.3113 8 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 3.3113 8 yes
GO:0002695 negative regulation of leukocyte activation 3.3113 5 yes
GO:0010948 negative regulation of cell cycle process 3.3113 6 yes
GO:0022408 negative regulation of cell-cell adhesion 3.3113 6 yes
GO:0030833 regulation of actin filament polymerization 3.3113 7 yes
GO:0030838 positive regulation of actin filament polymerization 3.3113 7 yes
GO:0031641 regulation of myelination 3.3113 4 yes
GO:0042130 negative regulation of T cell proliferation 2.6490 8 yes
GO:0050868 negative regulation of T cell activation 2.6490 7 yes
GO:0070830 bicellular tight junction assembly 2.6490 8 yes
GO:0120192 tight junction assembly 2.6490 7 yes
GO:0120193 tight junction organization 2.6490 6 yes
GO:1900744 regulation of p38MAPK cascade 2.6490 7 yes
GO:1901016 regulation of potassium ion transmembrane transporter activity 2.6490 6 yes
GO:1903038 negative regulation of leukocyte cell-cell adhesion 2.6490 7 yes
GO:1903753 negative regulation of p38MAPK cascade 2.6490 8 yes
GO:0006937 regulation of muscle contraction 2.6490 6 yes
GO:0006939 smooth muscle contraction 2.6490 5 yes
GO:0030953 astral microtubule organization 2.6490 4 yes
GO:0042982 amyloid precursor protein metabolic process 1.9868 4 yes
GO:0043622 cortical microtubule organization 1.9868 5 yes
GO:0048562 embryonic organ morphogenesis 1.9868 4 yes
GO:0048704 embryonic skeletal system morphogenesis 1.9868 5 yes
GO:0048705 skeletal system morphogenesis 1.9868 4 yes
GO:0051660 establishment of centrosome localization 1.9868 4 yes
GO:0051898 negative regulation of protein kinase B signaling 1.9868 7 yes
GO:0055117 regulation of cardiac muscle contraction 1.9868 7 yes
GO:0086004 regulation of cardiac muscle cell contraction 1.9868 6 yes
GO:1902305 regulation of sodium ion transmembrane transport 1.9868 7 yes
GO:1903115 regulation of actin filament-based movement 1.9868 5 yes
GO:0001658 branching involved in ureteric bud morphogenesis 1.9868 5 yes
GO:0002028 regulation of sodium ion transport 1.9868 7 yes
GO:0006942 regulation of striated muscle contraction 1.9868 7 yes
GO:0031579 membrane raft organization 1.9868 5 yes
GO:0048745 smooth muscle tissue development 1.3245 5 yes
GO:0098901 regulation of cardiac muscle cell action potential 1.3245 4 yes
GO:0098911 regulation of ventricular cardiac muscle cell action potential 1.3245 5 yes
GO:1903286 regulation of potassium ion import 1.3245 8 yes
GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1.3245 7 yes
GO:1903764 regulation of potassium ion export across plasma membrane 1.3245 8 yes
GO:0001771 immunological synapse formation 1.3245 4 yes
GO:0001935 endothelial cell proliferation 1.3245 4 yes
GO:0014821 phasic smooth muscle contraction 1.3245 6 yes
GO:0030432 peristalsis 1.3245 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in DLG1_HUMAN
DOID:331 central nervous system disease 4.6358 3 no
DOID:1289 neurodegenerative disease 2.6490 4 no
DOID:114 heart disease 1.9868 3 no
DOID:936 brain disease 1.9868 4 no
DOID:440 neuromuscular disease 1.9868 5 no
DOID:574 peripheral nervous system disease 1.9868 3 no
DOID:870 neuropathy 1.9868 4 no
DOID:0050700 cardiomyopathy 1.3245 4 no
DOID:0060036 intrinsic cardiomyopathy 1.3245 5 no
DOID:10273 heart conduction disease 1.3245 4 no
DOID:0050753 cerebellar ataxia 1.3245 6 no
DOID:0050951 hereditary ataxia 1.3245 5 no
DOID:0060038 specific developmental disorder 1.3245 3 no
DOID:1059 intellectual disability 1.3245 4 no
DOID:0111962 combined immunodeficiency 1.3245 4 no
DOID:612 primary immunodeficiency disease 1.3245 3 no
DOID:0050701 electroclinical syndrome 1.3245 6 no
DOID:1826 epilepsy 1.3245 5 no
DOID:3635 congenital myasthenic syndrome 1.3245 7 no
DOID:439 neuromuscular junction disease 1.3245 6 no
DOID:0050686 organ system cancer 1.3245 3 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
5HT2A_HUMAN [view entry] [view interactions] Low throughput yes yes
SSR1_HUMAN [view interactions] Low throughput no no
EPB41_HUMAN [view entry] [view interactions] Low throughput yes no
AT2B4_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNJ6_HUMAN [view interactions] Low throughput no no
UBE3A_HUMAN [view interactions] Low throughput no yes
CXB1_HUMAN [view interactions] Low throughput no yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
GUAD_HUMAN [view interactions] Low throughput no yes
KCNA5_HUMAN [view interactions] Low throughput no no
SCN5A_HUMAN [view interactions] Low throughput no no
NMDE2_HUMAN [view entry] [view interactions] Low throughput yes no
SHSA9_HUMAN [view entry] [view interactions] Low throughput yes no
ERBB4_HUMAN [view entry] [view interactions] Low throughput yes yes
IQEC3_HUMAN [view entry] [view interactions] Low throughput yes no
GRIA2_HUMAN [view entry] [view interactions] Low throughput yes yes
MYO6_HUMAN [view entry] [view interactions] Low throughput yes no
CSMD2_HUMAN [view interactions] Low throughput no no
KIF1B_HUMAN [view interactions] Low throughput no yes
TANC2_HUMAN [view entry] [view interactions] Low throughput yes yes
ANO9_HUMAN [view interactions] Low throughput no yes
LRP4_HUMAN [view entry] [view interactions] Low throughput yes yes
ARHG8_HUMAN [view interactions] Low throughput no yes
CLTR2_HUMAN [view interactions] Low throughput no no
CRIPT_HUMAN [view entry] [view interactions] Low throughput yes no
AGRA2_HUMAN [view interactions] Low throughput no no
KCNA4_HUMAN [view entry] [view interactions] Low throughput yes yes
KCJ12_HUMAN [view interactions] Low throughput no no
ADA10_HUMAN [view entry] [view interactions] Low throughput yes yes
ADRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] Low throughput yes no
TOPK_HUMAN [view interactions] Low throughput no no
LRFN2_HUMAN [view entry] [view interactions] Low throughput yes yes
LRFN1_HUMAN [view entry] [view interactions] Low throughput yes no
AT2B2_HUMAN [view entry] [view interactions] Low throughput yes yes
BAIP2_HUMAN [view entry] [view interactions] Low throughput yes yes
DGKZ_HUMAN [view entry] [view interactions] Low throughput yes yes
MP2K2_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNA3_HUMAN [view entry] [view interactions] Low throughput yes no
ADA17_HUMAN [view interactions] Low throughput no yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
GPSM2_HUMAN [view interactions] Low throughput no yes
SCN7A_HUMAN [view interactions] Low throughput no no
FBW1A_HUMAN [view interactions] Low throughput no yes
CRFR1_HUMAN [view interactions] Low throughput no yes
MAP1A_HUMAN [view entry] [view interactions] Low throughput yes yes
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
LCK_HUMAN [view entry] [view interactions] Low throughput yes no
KCNJ2_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNJ4_HUMAN [view entry] [view interactions] Low throughput yes no
GCYA2_HUMAN [view entry] [view interactions] Low throughput yes yes
NRCAM_HUMAN [view entry] [view interactions] Low throughput yes no
DGKI_HUMAN [view entry] [view interactions] Low throughput yes no
CSKP_HUMAN [view entry] [view interactions] Low throughput yes yes
KI13B_HUMAN [view interactions] Low throughput no yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
MK12_HUMAN [view interactions] Low throughput no no
APC_HUMAN [view entry] [view interactions] Low throughput yes no
NMDE1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRID2_HUMAN [view entry] [view interactions] Low throughput yes no
CRCM_HUMAN [view interactions] Low throughput no no
KS6A2_HUMAN [view interactions] Low throughput no yes
TANC1_HUMAN [view entry] [view interactions] Low throughput yes yes
EZRI_HUMAN [view entry] [view interactions] Low throughput yes no
IQEC2_HUMAN [view entry] [view interactions] Low throughput yes no
TJAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
LRRC1_HUMAN [view interactions] Low throughput no yes
TGFA_HUMAN [view interactions] Low throughput no yes
KCC2A_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTN2_HUMAN [view entry] [view interactions] Low throughput yes yes
CCG2_HUMAN [view entry] [view interactions] Low throughput yes no
GRIK2_HUMAN [view entry] [view interactions] Low throughput yes yes
AKAP5_HUMAN [view entry] [view interactions] Low throughput yes yes
CTNA1_HUMAN [view entry] [view interactions] Low throughput yes yes
MPP3_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG2_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
MARH2_HUMAN [view interactions] Low throughput no yes
NMDZ1_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNC1_HUMAN [view entry] [view interactions] Low throughput yes yes
MK14_HUMAN [view interactions] Low throughput no yes
CAV3_HUMAN [view interactions] Low throughput no no
DUS10_HUMAN [view entry] [view interactions] High throughput yes yes
MTMR2_HUMAN [view entry] [view interactions] High throughput yes no
CTBP2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
MAFB_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
FA20C_HUMAN [view interactions] High throughput no no
MKRN2_HUMAN [view interactions] High throughput no yes
CERS2_HUMAN [view interactions] High throughput no no
COPT1_HUMAN [view interactions] High throughput no no
SPAT2_HUMAN [view interactions] High throughput no yes
LIN7B_HUMAN [view entry] [view interactions] High throughput yes no
EFC11_HUMAN [view interactions] High throughput no no
TULP4_HUMAN [view interactions] High throughput no yes
ATS1_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOC_HUMAN [view interactions] High throughput no no
RHOD_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RND1_HUMAN [view interactions] High throughput no no
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PSPC1_HUMAN [view interactions] High throughput no yes
SRP09_HUMAN [view interactions] High throughput no no
CSK_HUMAN [view interactions] High throughput no yes
KHDR1_HUMAN [view interactions] High throughput no yes
AGRB1_HUMAN [view entry] [view interactions] High throughput yes no
CADM1_HUMAN [view entry] [view interactions] High throughput yes no
E41L2_HUMAN [view entry] [view interactions] High throughput yes yes
PI42B_HUMAN [view entry] [view interactions] High throughput yes no
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
PALS2_HUMAN [view interactions] High throughput no yes
GCYB1_HUMAN [view interactions] High throughput no yes
KCJ10_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
DNJ5B_HUMAN [view interactions] High throughput no no
DNJC5_HUMAN [view interactions] High throughput no yes
HS12A_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
B3GA1_HUMAN [view interactions] High throughput no yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
CXAR_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
CTND2_HUMAN [view entry] [view interactions] High throughput yes no
AFAD_HUMAN [view interactions] High throughput no yes
NXPE2_HUMAN [view interactions] High throughput no no
OCLN_HUMAN [view interactions] High throughput no no
RBP1_HUMAN [view entry] [view interactions] High throughput yes yes
PARD3_HUMAN [view interactions] High throughput no yes
EXOC4_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RASF6_HUMAN [view interactions] High throughput no yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
FRPD4_HUMAN [view entry] [view interactions] High throughput yes no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
SO1C1_HUMAN [view interactions] High throughput no no
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
PRR5_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
RNF12_HUMAN [view interactions] High throughput no yes
STX6_HUMAN [view interactions] High throughput no yes
PKP4_HUMAN [view entry] [view interactions] High throughput yes yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
IQEC1_HUMAN [view entry] [view interactions] High throughput yes yes
ZFPL1_HUMAN [view interactions] High throughput no yes
ZSC30_HUMAN [view interactions] High throughput no yes
UFO_HUMAN [view interactions] High throughput no no
PL8L1_HUMAN [view interactions] High throughput no no
DCNL1_HUMAN [view interactions] High throughput no yes
F163A_HUMAN [view interactions] High throughput no no
MARH3_HUMAN [view interactions] High throughput no no
SHSA7_HUMAN [view entry] [view interactions] High throughput yes no
F163B_HUMAN [view interactions] High throughput no yes
TBX15_HUMAN [view interactions] High throughput no yes
AGRA3_HUMAN [view interactions] High throughput no yes
AGRA1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP4_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP3_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP2_HUMAN [view entry] [view interactions] High throughput yes no
AMOT_HUMAN [view interactions] High throughput no no
LIN7A_HUMAN [view entry] [view interactions] High throughput yes yes
ZMYM1_HUMAN [view interactions] High throughput no no
RN146_HUMAN [view interactions] High throughput no yes
ARHGG_HUMAN [view interactions] High throughput no yes
ARHGQ_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
HNRPU_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
PRP4B_HUMAN [view interactions] High throughput no yes
PTHD1_HUMAN [view interactions] High throughput no no
ASAP1_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
AXIN1_HUMAN [view interactions] High throughput no yes
PK3CA_HUMAN [view entry] [view interactions] High throughput yes yes
P85A_HUMAN [view interactions] High throughput no yes
P85B_HUMAN [view interactions] High throughput no yes
CNKR2_HUMAN [view entry] [view interactions] High throughput yes no
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
FZD1_HUMAN [view interactions] High throughput no yes
FZD4_HUMAN [view interactions] High throughput no yes
FZD7_HUMAN [view interactions] High throughput no yes
M3K3_HUMAN [view interactions] High throughput no no
MAS_HUMAN [view interactions] High throughput no no
ADA1D_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TMM17_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view interactions] High throughput no yes
PTPRE_HUMAN [view interactions] High throughput no no
EPHA4_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA5_HUMAN [view interactions] High throughput no no
EPHA7_HUMAN [view entry] [view interactions] High throughput yes no
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
ADA22_HUMAN [view entry] [view interactions] High throughput yes no
ANO2_HUMAN [view interactions] High throughput no no
NMDE3_HUMAN [view entry] [view interactions] High throughput yes no
EVI5_HUMAN [view interactions] High throughput no yes
CAHM3_HUMAN [view interactions] High throughput no no
S14L3_HUMAN [view interactions] High throughput no no
MOT4_HUMAN [view entry] [view interactions] High throughput yes yes
VANG2_HUMAN [view interactions] High throughput no no
VANG1_HUMAN [view interactions] High throughput no no
HTR5B_HUMAN [view interactions] High throughput no yes
MTMR1_HUMAN [view interactions] High throughput no yes
NMDE4_HUMAN [view entry] [view interactions] High throughput yes yes
RAPSN_HUMAN [view entry] [view interactions] High throughput yes no
PABP2_HUMAN [view interactions] High throughput no yes
LRR3C_HUMAN [view interactions] High throughput no no
CD1D_HUMAN [view interactions] High throughput no yes
RT34_HUMAN [view interactions] High throughput no yes
SSBP2_HUMAN [view interactions] High throughput no yes
TPBGL_HUMAN [view interactions] High throughput no no
5HT2C_HUMAN [view interactions] High throughput no no
EAA3_HUMAN [view entry] [view interactions] High throughput yes yes
KCJ18_HUMAN [view interactions] High throughput no no
T178A_HUMAN [view interactions] High throughput no no
DB116_HUMAN [view interactions] High throughput no no
LIN7C_HUMAN [view entry] [view interactions] High throughput yes yes
APBA1_HUMAN [view interactions] High throughput no no
CBL_HUMAN [view interactions] High throughput no yes
ZAP70_HUMAN [view interactions] High throughput no no
WASP_HUMAN [view interactions] High throughput no yes
HUWE1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
DLG3_HUMAN [view entry] [view interactions] High throughput yes yes
KI26B_HUMAN [view interactions] High throughput no yes
MPP2_HUMAN [view entry] [view interactions] High throughput yes yes
EFNB3_HUMAN [view entry] [view interactions] High throughput yes yes
CXB7_HUMAN [view interactions] High throughput no no
PRDM1_HUMAN [view interactions] High throughput no yes
GPC5B_HUMAN [view entry] [view interactions] High throughput yes no
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
KIBRA_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
ESR2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
R144A_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
SCRIB_HUMAN [view entry] [view interactions] Computational yes no
MK11_HUMAN [view interactions] Computational no yes
CCG4_HUMAN [view entry] [view interactions] Computational yes no
KCND2_HUMAN [view entry] [view interactions] Computational yes yes
PAR6A_HUMAN [view interactions] Computational no yes
E41L1_HUMAN [view entry] [view interactions] Computational yes yes
GRIA3_HUMAN [view entry] [view interactions] Computational yes yes
PANX1_HUMAN [view interactions] Computational no no
SRC_HUMAN [view entry] [view interactions] Computational yes no
L2GL2_HUMAN [view interactions] Computational no yes
KIF17_HUMAN [view interactions] Computational no no
L2GL1_HUMAN [view entry] [view interactions] Computational yes yes
GRIA4_HUMAN [view entry] [view interactions] Computational yes no
MK13_HUMAN [view interactions] Computational no yes
CCG3_HUMAN [view entry] [view interactions] Computational yes no
NCALD_HUMAN [view entry] [view interactions] Computational yes yes
PICK1_HUMAN [view entry] [view interactions] Computational yes yes
KSR1_HUMAN [view interactions] Computational no yes
GRIK5_HUMAN [view entry] [view interactions] Computational yes no
CCG8_HUMAN [view entry] [view interactions] Computational yes no
KPCZ_HUMAN [view entry] [view interactions] Computational yes yes
MDM2_HUMAN [view interactions] Computational no yes
MPP7_HUMAN [view entry] [view interactions] Computational yes no
KCND3_HUMAN [view entry] [view interactions] Computational yes yes
CTND1_HUMAN [view entry] [view interactions] Computational yes no