EFNB3_HUMAN
(Microbial infection) Acts as a receptor for nipah virus and hendra virus. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EFNB3_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 42.1053 | 4 | no |
GO:0019901 | protein kinase binding | 42.1053 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 39.4737 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 39.4737 | 4 | no |
GO:0017076 | purine nucleotide binding | 39.4737 | 4 | no |
GO:0016301 | kinase activity | 28.9474 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 26.3158 | 4 | yes |
GO:0046875 | ephrin receptor binding | 23.6842 | 4 | yes |
GO:0032559 | adenyl ribonucleotide binding | 21.0526 | 5 | no |
GO:0046872 | metal ion binding | 21.0526 | 4 | no |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 21.0526 | 4 | no |
GO:0005524 | ATP binding | 21.0526 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 21.0526 | 5 | no |
GO:0004713 | protein tyrosine kinase activity | 18.4211 | 4 | yes |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 13.1579 | 5 | yes |
GO:0005003 | ephrin receptor activity | 13.1579 | 6 | yes |
GO:0005005 | transmembrane-ephrin receptor activity | 13.1579 | 7 | yes |
GO:0019199 | transmembrane receptor protein kinase activity | 13.1579 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EFNB3_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 78.9474 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 68.4211 | 4 | yes |
GO:0010646 | regulation of cell communication | 68.4211 | 4 | no |
GO:0051128 | regulation of cellular component organization | 65.7895 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 65.7895 | 4 | no |
GO:0009966 | regulation of signal transduction | 63.1579 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 63.1579 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 63.1579 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 63.1579 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 60.5263 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 57.8947 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 57.8947 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 55.2632 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 55.2632 | 6 | no |
GO:0042325 | regulation of phosphorylation | 55.2632 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 55.2632 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 52.6316 | 7 | no |
GO:0031399 | regulation of protein modification process | 52.6316 | 6 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 52.6316 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 52.6316 | 5 | no |
GO:0030030 | cell projection organization | 50.0000 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 50.0000 | 5 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 47.3684 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 47.3684 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 47.3684 | 7 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 44.7368 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 44.7368 | 6 | no |
GO:0051338 | regulation of transferase activity | 44.7368 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 42.1053 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 42.1053 | 5 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 42.1053 | 8 | no |
GO:0031401 | positive regulation of protein modification process | 42.1053 | 7 | no |
GO:0043085 | positive regulation of catalytic activity | 42.1053 | 4 | no |
GO:0043549 | regulation of kinase activity | 42.1053 | 5 | no |
GO:0051049 | regulation of transport | 42.1053 | 4 | no |
GO:0010468 | regulation of gene expression | 42.1053 | 5 | no |
GO:0006996 | organelle organization | 42.1053 | 4 | no |
GO:0051347 | positive regulation of transferase activity | 39.4737 | 5 | no |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 36.8421 | 4 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 36.8421 | 5 | yes |
GO:0031175 | neuron projection development | 36.8421 | 6 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 36.8421 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 36.8421 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 36.8421 | 5 | no |
GO:0010647 | positive regulation of cell communication | 36.8421 | 5 | no |
GO:0023056 | positive regulation of signaling | 36.8421 | 4 | no |
GO:0033674 | positive regulation of kinase activity | 36.8421 | 6 | no |
GO:0042127 | regulation of cell population proliferation | 36.8421 | 4 | no |
GO:0043408 | regulation of MAPK cascade | 36.8421 | 6 | no |
GO:0045859 | regulation of protein kinase activity | 36.8421 | 6 | no |
GO:0033043 | regulation of organelle organization | 36.8421 | 5 | no |
GO:0045595 | regulation of cell differentiation | 34.2105 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 34.2105 | 4 | no |
GO:0080134 | regulation of response to stress | 34.2105 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 34.2105 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 34.2105 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.2105 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 34.2105 | 5 | no |
GO:0051129 | negative regulation of cellular component organization | 31.5789 | 5 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 31.5789 | 4 | no |
GO:0008284 | positive regulation of cell population proliferation | 31.5789 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 31.5789 | 5 | no |
GO:0016310 | phosphorylation | 31.5789 | 5 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 31.5789 | 5 | no |
GO:0022607 | cellular component assembly | 31.5789 | 4 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 31.5789 | 5 | no |
GO:0051050 | positive regulation of transport | 31.5789 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.5789 | 5 | no |
GO:0007010 | cytoskeleton organization | 31.5789 | 5 | no |
GO:0016192 | vesicle-mediated transport | 31.5789 | 4 | no |
GO:0030155 | regulation of cell adhesion | 28.9474 | 4 | yes |
GO:0006468 | protein phosphorylation | 28.9474 | 5 | no |
GO:0031346 | positive regulation of cell projection organization | 28.9474 | 6 | no |
GO:0036211 | protein modification process | 28.9474 | 4 | no |
GO:0043412 | macromolecule modification | 28.9474 | 4 | no |
GO:0045860 | positive regulation of protein kinase activity | 28.9474 | 7 | no |
GO:0051094 | positive regulation of developmental process | 28.9474 | 4 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 28.9474 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 28.9474 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 28.9474 | 6 | no |
GO:0010638 | positive regulation of organelle organization | 28.9474 | 6 | no |
GO:0032970 | regulation of actin filament-based process | 28.9474 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 28.9474 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 28.9474 | 6 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 28.9474 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 28.9474 | 6 | no |
GO:0048013 | ephrin receptor signaling pathway | 26.3158 | 6 | yes |
GO:0060284 | regulation of cell development | 26.3158 | 5 | yes |
GO:0022604 | regulation of cell morphogenesis | 26.3158 | 5 | no |
GO:0030334 | regulation of cell migration | 26.3158 | 5 | no |
GO:0050804 | modulation of chemical synaptic transmission | 26.3158 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 26.3158 | 4 | no |
GO:2000145 | regulation of cell motility | 26.3158 | 4 | no |
GO:0008104 | protein localization | 26.3158 | 4 | no |
GO:0010941 | regulation of cell death | 26.3158 | 4 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 26.3158 | 5 | no |
GO:0042981 | regulation of apoptotic process | 26.3158 | 6 | no |
GO:0043067 | regulation of programmed cell death | 26.3158 | 5 | no |
GO:0060627 | regulation of vesicle-mediated transport | 26.3158 | 4 | no |
GO:0060341 | regulation of cellular localization | 26.3158 | 4 | no |
GO:0002684 | positive regulation of immune system process | 23.6842 | 4 | yes |
GO:0010975 | regulation of neuron projection development | 23.6842 | 7 | yes |
GO:2000026 | regulation of multicellular organismal development | 23.6842 | 4 | yes |
GO:0030335 | positive regulation of cell migration | 23.6842 | 6 | no |
GO:0032101 | regulation of response to external stimulus | 23.6842 | 4 | no |
GO:0040017 | positive regulation of locomotion | 23.6842 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 23.6842 | 6 | no |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 23.6842 | 7 | no |
GO:0071310 | cellular response to organic substance | 23.6842 | 4 | no |
GO:2000147 | positive regulation of cell motility | 23.6842 | 5 | no |
GO:0007411 | axon guidance | 21.0526 | 8 | yes |
GO:0045785 | positive regulation of cell adhesion | 21.0526 | 5 | yes |
GO:0051093 | negative regulation of developmental process | 21.0526 | 4 | yes |
GO:0051960 | regulation of nervous system development | 21.0526 | 5 | yes |
GO:0097485 | neuron projection guidance | 21.0526 | 7 | yes |
GO:0099537 | trans-synaptic signaling | 21.0526 | 4 | yes |
GO:0043410 | positive regulation of MAPK cascade | 21.0526 | 7 | no |
GO:0045597 | positive regulation of cell differentiation | 21.0526 | 5 | no |
GO:0051336 | regulation of hydrolase activity | 21.0526 | 4 | no |
GO:0071900 | regulation of protein serine/threonine kinase activity | 21.0526 | 7 | no |
GO:0071902 | positive regulation of protein serine/threonine kinase activity | 21.0526 | 8 | no |
GO:0080135 | regulation of cellular response to stress | 21.0526 | 4 | no |
GO:0043254 | regulation of protein-containing complex assembly | 21.0526 | 5 | no |
GO:0051726 | regulation of cell cycle | 21.0526 | 4 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.0526 | 6 | no |
GO:0051495 | positive regulation of cytoskeleton organization | 21.0526 | 7 | no |
GO:0110053 | regulation of actin filament organization | 21.0526 | 6 | no |
GO:1902903 | regulation of supramolecular fiber organization | 21.0526 | 5 | no |
GO:0030100 | regulation of endocytosis | 21.0526 | 5 | no |
GO:0032880 | regulation of protein localization | 21.0526 | 5 | no |
GO:0045596 | negative regulation of cell differentiation | 18.4211 | 5 | yes |
GO:0050767 | regulation of neurogenesis | 18.4211 | 6 | yes |
GO:0050770 | regulation of axonogenesis | 18.4211 | 5 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 18.4211 | 4 | yes |
GO:0002694 | regulation of leukocyte activation | 15.7895 | 4 | yes |
GO:0007399 | nervous system development | 15.7895 | 4 | yes |
GO:0022407 | regulation of cell-cell adhesion | 15.7895 | 5 | yes |
GO:0050865 | regulation of cell activation | 15.7895 | 4 | yes |
GO:0051249 | regulation of lymphocyte activation | 15.7895 | 5 | yes |
GO:0002696 | positive regulation of leukocyte activation | 13.1579 | 5 | yes |
GO:0010977 | negative regulation of neuron projection development | 13.1579 | 7 | yes |
GO:0031345 | negative regulation of cell projection organization | 13.1579 | 6 | yes |
GO:0050863 | regulation of T cell activation | 13.1579 | 6 | yes |
GO:0050867 | positive regulation of cell activation | 13.1579 | 5 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 13.1579 | 6 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 13.1579 | 6 | yes |
GO:0010721 | negative regulation of cell development | 10.5263 | 6 | yes |
GO:0022409 | positive regulation of cell-cell adhesion | 10.5263 | 6 | yes |
GO:0050768 | negative regulation of neurogenesis | 10.5263 | 6 | yes |
GO:0050771 | negative regulation of axonogenesis | 10.5263 | 6 | yes |
GO:0050870 | positive regulation of T cell activation | 10.5263 | 7 | yes |
GO:0051961 | negative regulation of nervous system development | 10.5263 | 5 | yes |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 10.5263 | 7 | yes |
GO:0007628 | adult walking behavior | 7.8947 | 5 | yes |
GO:0008344 | adult locomotory behavior | 7.8947 | 4 | yes |
GO:0090659 | walking behavior | 7.8947 | 4 | yes |
GO:0099545 | trans-synaptic signaling by trans-synaptic complex | 7.8947 | 5 | yes |
GO:0099550 | trans-synaptic signaling, modulating synaptic transmission | 7.8947 | 5 | yes |
GO:0099557 | trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission | 7.8947 | 6 | yes |
GO:0016198 | axon choice point recognition | 5.2632 | 4 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in EFNB3_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 7.8947 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 7.8947 | 5 | no |
DOID:114 | heart disease | 7.8947 | 3 | no |
DOID:2843 | long QT syndrome | 7.8947 | 6 | no |
DOID:10273 | heart conduction disease | 5.2632 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
EPHA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VLDLR_HUMAN | [view interactions] | Low throughput | no | yes |
DAB1_HUMAN | [view interactions] | Low throughput | no | yes |
LRP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RELN_HUMAN | [view interactions] | Low throughput | no | no |
SDCB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EPHB3_HUMAN | [view interactions] | Low throughput | no | yes |
RHBL2_HUMAN | [view interactions] | Low throughput | no | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EFNB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DPA1_HUMAN | [view interactions] | High throughput | no | yes |
RA51C_HUMAN | [view interactions] | High throughput | no | no |
THUM3_HUMAN | [view interactions] | High throughput | no | yes |
EVI5L_HUMAN | [view interactions] | High throughput | no | yes |
PLCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEN6A_HUMAN | [view interactions] | High throughput | no | yes |
PKN3_HUMAN | [view interactions] | High throughput | no | yes |
MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TBB8_HUMAN | [view interactions] | High throughput | no | no |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LEG1_HUMAN | [view interactions] | High throughput | no | yes |
TCAF2_HUMAN | [view interactions] | High throughput | no | no |
DEN11_HUMAN | [view interactions] | High throughput | no | yes |
TNFL8_HUMAN | [view interactions] | High throughput | no | no |
GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
F221B_HUMAN | [view interactions] | High throughput | no | no |
P2RX7_HUMAN | [view interactions] | High throughput | no | yes |
ELOC_HUMAN | [view interactions] | High throughput | no | no |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AATF_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TB22A_HUMAN | [view interactions] | High throughput | no | yes |
RGS3_HUMAN | [view interactions] | High throughput | no | no |
DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RTEL1_HUMAN | [view interactions] | High throughput | no | no |
CDYL_HUMAN | [view interactions] | High throughput | no | yes |
TRI11_HUMAN | [view interactions] | High throughput | no | yes |
IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
NAGAB_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP30_HUMAN | [view interactions] | High throughput | no | yes |
MTMR8_HUMAN | [view interactions] | High throughput | no | no |
F234A_HUMAN | [view interactions] | High throughput | no | yes |
RYK_HUMAN | [view interactions] | High throughput | no | no |
NHLC3_HUMAN | [view interactions] | High throughput | no | yes |
FUCO2_HUMAN | [view interactions] | High throughput | no | no |
MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
CLC4A_HUMAN | [view interactions] | High throughput | no | no |
TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HCST_HUMAN | [view interactions] | High throughput | no | no |
CALL3_HUMAN | [view interactions] | High throughput | no | yes |
MAGA8_HUMAN | [view interactions] | High throughput | no | no |
EPHB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EPHA3_HUMAN | [view interactions] | Computational | no | yes |
SH3G2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EPHA1_HUMAN | [view interactions] | Computational | no | yes |
EPHB1_HUMAN | [view interactions] | Computational | no | no |
RASA1_HUMAN | [view interactions] | Computational | no | yes |
ITSN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EPHB4_HUMAN | [view interactions] | Computational | no | yes |
SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EPHA7_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MMP9_HUMAN | [view interactions] | Computational | no | no |
EPHAA_HUMAN | [view interactions] | Computational | no | yes |
NCK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MMP2_HUMAN | [view interactions] | Computational | no | no |
CRK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GRB7_HUMAN | [view interactions] | Computational | no | no |
PAXI_HUMAN | [view interactions] | Computational | no | yes |
ML12A_HUMAN | [view interactions] | Computational | no | no |
PAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KALRN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MP2K1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WASL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EFNB1_HUMAN | [view interactions] | Computational | no | yes |
EPHA8_HUMAN | [view interactions] | Computational | no | no |
EPHA2_HUMAN | [view interactions] | Computational | no | no |
RRAS_HUMAN | [view interactions] | Computational | no | yes |