Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EFNB3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

(Microbial infection) Acts as a receptor for nipah virus and hendra virus. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in EFNB3_HUMAN
GO:0043168 anion binding 40.0000 4 no
GO:0043169 cation binding 36.0000 4 no
GO:0046872 metal ion binding 36.0000 5 no
GO:0019900 kinase binding 36.0000 4 no
GO:0000166 nucleotide binding 32.0000 4 no
GO:0017076 purine nucleotide binding 32.0000 5 no
GO:0032555 purine ribonucleotide binding 32.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 32.0000 4 no
GO:0019901 protein kinase binding 28.0000 5 no
GO:0016301 kinase activity 24.0000 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 20.0000 4 yes
GO:0046875 ephrin receptor binding 16.0000 4 yes
GO:0004713 protein tyrosine kinase activity 12.0000 4 yes
GO:0004714 transmembrane receptor protein tyrosine kinase activity 12.0000 5 yes
GO:0005003 ephrin receptor activity 12.0000 6 yes
GO:0005005 transmembrane-ephrin receptor activity 12.0000 7 yes
GO:0019199 transmembrane receptor protein kinase activity 12.0000 4 yes
GO:0001618 virus receptor activity 8.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in EFNB3_HUMAN
GO:0048522 positive regulation of cellular process 80.0000 4 yes
GO:0010646 regulation of cell communication 68.0000 4 yes
GO:0048523 negative regulation of cellular process 60.0000 4 yes
GO:0051128 regulation of cellular component organization 60.0000 4 yes
GO:0031323 regulation of cellular metabolic process 56.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 56.0000 4 no
GO:0051130 positive regulation of cellular component organization 52.0000 5 yes
GO:0080090 regulation of primary metabolic process 52.0000 4 no
GO:0009966 regulation of signal transduction 52.0000 4 no
GO:1902531 regulation of intracellular signal transduction 48.0000 5 no
GO:0009893 positive regulation of metabolic process 44.0000 4 no
GO:0010562 positive regulation of phosphorus metabolic process 44.0000 6 no
GO:0019220 regulation of phosphate metabolic process 44.0000 6 no
GO:0031325 positive regulation of cellular metabolic process 44.0000 5 no
GO:0042325 regulation of phosphorylation 44.0000 7 no
GO:0042327 positive regulation of phosphorylation 44.0000 8 no
GO:0045937 positive regulation of phosphate metabolic process 44.0000 7 no
GO:0051174 regulation of phosphorus metabolic process 44.0000 5 no
GO:0050804 modulation of chemical synaptic transmission 40.0000 5 yes
GO:0099177 regulation of trans-synaptic signaling 40.0000 4 yes
GO:0001932 regulation of protein phosphorylation 40.0000 7 no
GO:0001934 positive regulation of protein phosphorylation 40.0000 8 no
GO:0009889 regulation of biosynthetic process 40.0000 4 no
GO:0010556 regulation of macromolecule biosynthetic process 40.0000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 40.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 40.0000 5 no
GO:0031399 regulation of protein modification process 40.0000 6 no
GO:0031401 positive regulation of protein modification process 40.0000 7 no
GO:0051246 regulation of protein metabolic process 40.0000 5 no
GO:0051247 positive regulation of protein metabolic process 40.0000 6 no
GO:0051049 regulation of transport 40.0000 4 no
GO:0010647 positive regulation of cell communication 40.0000 5 yes
GO:0023056 positive regulation of signaling 40.0000 4 yes
GO:0030030 cell projection organization 40.0000 4 yes
GO:0120036 plasma membrane bounded cell projection organization 36.0000 5 yes
GO:0010468 regulation of gene expression 36.0000 6 no
GO:0043085 positive regulation of catalytic activity 36.0000 4 no
GO:0051338 regulation of transferase activity 36.0000 4 no
GO:0051347 positive regulation of transferase activity 36.0000 5 no
GO:0042127 regulation of cell population proliferation 36.0000 4 no
GO:0141124 intracellular signaling cassette 36.0000 4 no
GO:0022603 regulation of anatomical structure morphogenesis 36.0000 4 yes
GO:0031344 regulation of cell projection organization 36.0000 5 yes
GO:0045595 regulation of cell differentiation 36.0000 4 yes
GO:0051240 positive regulation of multicellular organismal process 32.0000 4 yes
GO:0051960 regulation of nervous system development 32.0000 5 yes
GO:2000026 regulation of multicellular organismal development 32.0000 4 yes
GO:0033674 positive regulation of kinase activity 32.0000 6 no
GO:0043549 regulation of kinase activity 32.0000 5 no
GO:0045859 regulation of protein kinase activity 32.0000 6 no
GO:0045860 positive regulation of protein kinase activity 32.0000 7 no
GO:0008284 positive regulation of cell population proliferation 32.0000 5 no
GO:0009892 negative regulation of metabolic process 32.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 32.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 32.0000 5 no
GO:0048584 positive regulation of response to stimulus 32.0000 4 no
GO:0051050 positive regulation of transport 32.0000 4 no
GO:0050767 regulation of neurogenesis 28.0000 6 yes
GO:0051129 negative regulation of cellular component organization 28.0000 5 yes
GO:0060284 regulation of cell development 28.0000 5 yes
GO:0099536 synaptic signaling 28.0000 4 yes
GO:0099537 trans-synaptic signaling 28.0000 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.0000 6 yes
GO:0006996 organelle organization 28.0000 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.0000 5 no
GO:0051094 positive regulation of developmental process 28.0000 4 no
GO:0043408 regulation of MAPK cascade 28.0000 6 no
GO:0009967 positive regulation of signal transduction 28.0000 5 no
GO:0008104 protein localization 28.0000 4 no
GO:0034762 regulation of transmembrane transport 28.0000 4 no
GO:0044057 regulation of system process 28.0000 4 no
GO:0022607 cellular component assembly 28.0000 4 no
GO:0031175 neuron projection development 28.0000 6 yes
GO:0050807 regulation of synapse organization 24.0000 5 yes
GO:0051093 negative regulation of developmental process 24.0000 4 yes
GO:0097485 neuron projection guidance 24.0000 7 yes
GO:0006355 regulation of DNA-templated transcription 24.0000 7 no
GO:0022604 regulation of cell morphogenesis 24.0000 5 no
GO:0031346 positive regulation of cell projection organization 24.0000 6 no
GO:0051252 regulation of RNA metabolic process 24.0000 5 no
GO:2001141 regulation of RNA biosynthetic process 24.0000 6 no
GO:0006796 phosphate-containing compound metabolic process 24.0000 4 no
GO:0016310 phosphorylation 24.0000 5 no
GO:0051726 regulation of cell cycle 24.0000 4 no
GO:0022898 regulation of transmembrane transporter activity 24.0000 4 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 24.0000 5 no
GO:0034765 regulation of monoatomic ion transmembrane transport 24.0000 5 no
GO:0043269 regulation of monoatomic ion transport 24.0000 5 no
GO:0043270 positive regulation of monoatomic ion transport 24.0000 5 no
GO:0072657 protein localization to membrane 24.0000 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 24.0000 4 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 24.0000 5 yes
GO:0007411 axon guidance 24.0000 8 yes
GO:0010975 regulation of neuron projection development 24.0000 7 yes
GO:0044087 regulation of cellular component biogenesis 24.0000 4 yes
GO:0045596 negative regulation of cell differentiation 24.0000 5 yes
GO:0050806 positive regulation of synaptic transmission 20.0000 5 yes
GO:0051241 negative regulation of multicellular organismal process 20.0000 4 yes
GO:0050770 regulation of axonogenesis 16.0000 5 yes
GO:0002684 positive regulation of immune system process 16.0000 4 yes
GO:0007399 nervous system development 16.0000 4 yes
GO:0010977 negative regulation of neuron projection development 16.0000 7 yes
GO:0030155 regulation of cell adhesion 16.0000 4 yes
GO:0031345 negative regulation of cell projection organization 16.0000 6 yes
GO:0050768 negative regulation of neurogenesis 12.0000 6 yes
GO:0050771 negative regulation of axonogenesis 12.0000 6 yes
GO:0050863 regulation of T cell activation 12.0000 6 yes
GO:0050865 regulation of cell activation 12.0000 4 yes
GO:0051249 regulation of lymphocyte activation 12.0000 5 yes
GO:0051961 negative regulation of nervous system development 12.0000 5 yes
GO:0090659 walking behavior 12.0000 4 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 12.0000 6 yes
GO:0002694 regulation of leukocyte activation 12.0000 4 yes
GO:0007628 adult walking behavior 12.0000 5 yes
GO:0008344 adult locomotory behavior 12.0000 4 yes
GO:0010721 negative regulation of cell development 12.0000 6 yes
GO:0022407 regulation of cell-cell adhesion 12.0000 5 yes
GO:0045785 positive regulation of cell adhesion 12.0000 5 yes
GO:0048013 ephrin receptor signaling pathway 12.0000 6 yes
GO:0050867 positive regulation of cell activation 8.0000 5 yes
GO:0050870 positive regulation of T cell activation 8.0000 7 yes
GO:0051251 positive regulation of lymphocyte activation 8.0000 6 yes
GO:0051963 regulation of synapse assembly 8.0000 6 yes
GO:0099174 regulation of presynapse organization 8.0000 6 yes
GO:0099545 trans-synaptic signaling by trans-synaptic complex 8.0000 6 yes
GO:0099550 trans-synaptic signaling, modulating synaptic transmission 8.0000 6 yes
GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission 8.0000 7 yes
GO:1901888 regulation of cell junction assembly 8.0000 5 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 8.0000 7 yes
GO:1905606 regulation of presynapse assembly 8.0000 7 yes
GO:1905608 positive regulation of presynapse assembly 8.0000 6 yes
GO:0002696 positive regulation of leukocyte activation 8.0000 5 yes
GO:0016198 axon choice point recognition 8.0000 4 yes
GO:0022409 positive regulation of cell-cell adhesion 8.0000 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
EPHA4_HUMAN [view entry] [view interactions] Low throughput yes yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
VLDLR_HUMAN [view interactions] Low throughput no yes
LRP8_HUMAN [view entry] [view interactions] Low throughput yes no
RELN_HUMAN [view entry] [view interactions] Low throughput yes no
DAB1_HUMAN [view interactions] Low throughput no yes
SDCB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PARD3_HUMAN [view interactions] Low throughput no yes
GRIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
EPHB3_HUMAN [view interactions] Low throughput no yes
RHBL2_HUMAN [view interactions] Low throughput no yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
EFNB3_HUMAN [view entry] [view interactions] Low throughput yes yes
DPA1_HUMAN [view interactions] High throughput no yes
DEN11_HUMAN [view interactions] High throughput no yes
TCAF2_HUMAN [view interactions] High throughput no no
RA51C_HUMAN [view interactions] High throughput no no
LEG1_HUMAN [view interactions] High throughput no yes
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
TBB8_HUMAN [view interactions] High throughput no no
MPP7_HUMAN [view entry] [view interactions] High throughput yes no
PKN3_HUMAN [view interactions] High throughput no yes
DEN6A_HUMAN [view interactions] High throughput no yes
PLCD3_HUMAN [view entry] [view interactions] High throughput yes yes
EVI5L_HUMAN [view interactions] High throughput no yes
THUM3_HUMAN [view interactions] High throughput no yes
TNFL8_HUMAN [view interactions] High throughput no no
GLU2B_HUMAN [view interactions] High throughput no yes
F221B_HUMAN [view interactions] High throughput no no
P2RX7_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
ELOC_HUMAN [view interactions] High throughput no no
AATF_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
TB22A_HUMAN [view interactions] High throughput no yes
RGS3_HUMAN [view interactions] High throughput no no
DLG1_HUMAN [view entry] [view interactions] High throughput yes yes
RTEL1_HUMAN [view interactions] High throughput no no
CDYL_HUMAN [view interactions] High throughput no yes
TRI11_HUMAN [view interactions] High throughput no yes
IGSF8_HUMAN [view entry] [view interactions] High throughput yes no
FACD2_HUMAN [view interactions] High throughput no no
NAGAB_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP30_HUMAN [view interactions] High throughput no yes
MTMR8_HUMAN [view interactions] High throughput no no
F234A_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view entry] [view interactions] High throughput yes no
NHLC3_HUMAN [view interactions] High throughput no yes
FUCO2_HUMAN [view interactions] High throughput no no
MTMR1_HUMAN [view interactions] High throughput no yes
CLC4A_HUMAN [view interactions] High throughput no no
TBB4B_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
HCST_HUMAN [view interactions] High throughput no no
CALL3_HUMAN [view interactions] High throughput no yes
MAGA8_HUMAN [view interactions] High throughput no no