KCNJ2_HUMAN
Evidence for PS localization
Functions
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 67 | Arg | Trp | LongQTsyndrome7(LQT7) | - |
| 71 | Asp | Val | LongQTsyndrome7(LQT7) | - |
| 186 | Pro | Leu | LongQTsyndrome7(LQT7) | - |
| 216 | Asn | His | LongQTsyndrome7(LQT7) | - |
| 218 | Arg | Trp | LongQTsyndrome7(LQT7) | - |
| 300 | Gly | Val | LongQTsyndrome7(LQT7) | - |
| 302 | Val | Met | LongQTsyndrome7(LQT7) | - |
| 172 | Asp | Asn | ShortQTsyndrome3(SQT3) | - |
| 54 | Cys | Phe | LongQTsyndrome7(LQT7) | - |
| 75 | Thr | Arg | LongQTsyndrome7(LQT7) | - |
| 93 | Val | Ile | Atrialfibrillation,familial,9(ATFB9) | - |
| 305 | Thr | Pro | LongQTsyndrome7(LQT7) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in KCNJ2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 26.7442 | 4 | yes |
| GO:0043169 | cation binding | 23.2558 | 4 | no |
| GO:0046872 | metal ion binding | 23.2558 | 5 | no |
| GO:0000166 | nucleotide binding | 22.0930 | 4 | no |
| GO:0005524 | ATP binding | 20.9302 | 5 | no |
| GO:0017076 | purine nucleotide binding | 20.9302 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 20.9302 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 20.9302 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.9302 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.9302 | 4 | no |
| GO:0035091 | phosphatidylinositol binding | 12.7907 | 4 | yes |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 8.1395 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 8.1395 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 8.1395 | 5 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 6.9767 | 5 | yes |
| GO:1902936 | phosphatidylinositol bisphosphate binding | 6.9767 | 6 | yes |
| GO:0005216 | monoatomic ion channel activity | 4.6512 | 4 | yes |
| GO:0005261 | monoatomic cation channel activity | 4.6512 | 5 | yes |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | 4.6512 | 5 | yes |
| GO:0015267 | channel activity | 4.6512 | 4 | yes |
| GO:0015276 | ligand-gated monoatomic ion channel activity | 4.6512 | 5 | yes |
| GO:0022834 | ligand-gated channel activity | 4.6512 | 6 | yes |
| GO:0022836 | gated channel activity | 4.6512 | 5 | yes |
| GO:0099094 | ligand-gated monoatomic cation channel activity | 4.6512 | 6 | yes |
| GO:0005242 | inward rectifier potassium channel activity | 3.4884 | 7 | yes |
| GO:0005244 | voltage-gated monoatomic ion channel activity | 3.4884 | 5 | yes |
| GO:0005249 | voltage-gated potassium channel activity | 3.4884 | 7 | yes |
| GO:0005267 | potassium channel activity | 3.4884 | 6 | yes |
| GO:0015079 | potassium ion transmembrane transporter activity | 3.4884 | 6 | yes |
| GO:0022832 | voltage-gated channel activity | 3.4884 | 6 | yes |
| GO:0022843 | voltage-gated monoatomic cation channel activity | 3.4884 | 6 | yes |
| GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | 2.3256 | 8 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in KCNJ2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.4651 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 48.8372 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 46.5116 | 4 | no |
| GO:0008104 | protein localization | 45.3488 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 44.1860 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.0233 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 39.5349 | 4 | no |
| GO:0051049 | regulation of transport | 37.2093 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 37.2093 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 34.8837 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 34.8837 | 5 | no |
| GO:0023056 | positive regulation of signaling | 33.7209 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.7209 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.7209 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 32.5581 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 32.5581 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.3953 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 31.3953 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 30.2326 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.2326 | 5 | no |
| GO:0022607 | cellular component assembly | 29.0698 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 29.0698 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 27.9070 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.5814 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 25.5814 | 5 | no |
| GO:0071702 | organic substance transport | 25.5814 | 4 | no |
| GO:0072657 | protein localization to membrane | 25.5814 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 24.4186 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.4186 | 4 | no |
| GO:0032880 | regulation of protein localization | 24.4186 | 5 | no |
| GO:0060341 | regulation of cellular localization | 24.4186 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.4186 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.2558 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.2558 | 4 | no |
| GO:0015031 | protein transport | 23.2558 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 23.2558 | 4 | no |
| GO:0051050 | positive regulation of transport | 22.0930 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.0930 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 22.0930 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 22.0930 | 4 | no |
| GO:0043412 | macromolecule modification | 22.0930 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.0930 | 4 | no |
| GO:0006996 | organelle organization | 22.0930 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 22.0930 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 20.9302 | 5 | no |
| GO:0030030 | cell projection organization | 20.9302 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.9302 | 6 | no |
| GO:0036211 | protein modification process | 20.9302 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 20.9302 | 4 | no |
| GO:1990778 | protein localization to cell periphery | 20.9302 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.9302 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 20.9302 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 20.9302 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.9302 | 5 | no |
| GO:0034762 | regulation of transmembrane transport | 18.6047 | 4 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 16.2791 | 5 | yes |
| GO:0010959 | regulation of metal ion transport | 15.1163 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 15.1163 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 13.9535 | 5 | yes |
| GO:0006811 | monoatomic ion transport | 12.7907 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 12.7907 | 5 | yes |
| GO:0030001 | metal ion transport | 12.7907 | 6 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 12.7907 | 5 | yes |
| GO:0044057 | regulation of system process | 12.7907 | 4 | yes |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 11.6279 | 6 | yes |
| GO:0090257 | regulation of muscle system process | 10.4651 | 5 | yes |
| GO:0098657 | import into cell | 10.4651 | 4 | yes |
| GO:0043270 | positive regulation of monoatomic ion transport | 9.3023 | 5 | yes |
| GO:0098655 | monoatomic cation transmembrane transport | 9.3023 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 9.3023 | 4 | yes |
| GO:0006873 | intracellular monoatomic ion homeostasis | 8.1395 | 4 | yes |
| GO:0008016 | regulation of heart contraction | 8.1395 | 6 | yes |
| GO:0030003 | intracellular monoatomic cation homeostasis | 8.1395 | 5 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 8.1395 | 5 | yes |
| GO:0055080 | monoatomic cation homeostasis | 8.1395 | 4 | yes |
| GO:1903522 | regulation of blood circulation | 8.1395 | 5 | yes |
| GO:0006937 | regulation of muscle contraction | 6.9767 | 6 | yes |
| GO:0032970 | regulation of actin filament-based process | 6.9767 | 4 | yes |
| GO:0006942 | regulation of striated muscle contraction | 5.8140 | 7 | yes |
| GO:0055117 | regulation of cardiac muscle contraction | 5.8140 | 7 | yes |
| GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 4.6512 | 6 | yes |
| GO:0043266 | regulation of potassium ion transport | 4.6512 | 7 | yes |
| GO:0043268 | positive regulation of potassium ion transport | 4.6512 | 6 | yes |
| GO:0071260 | cellular response to mechanical stimulus | 4.6512 | 4 | yes |
| GO:0086004 | regulation of cardiac muscle cell contraction | 4.6512 | 6 | yes |
| GO:0098659 | inorganic cation import across plasma membrane | 4.6512 | 5 | yes |
| GO:0099587 | inorganic ion import across plasma membrane | 4.6512 | 4 | yes |
| GO:1901379 | regulation of potassium ion transmembrane transport | 4.6512 | 7 | yes |
| GO:1903115 | regulation of actin filament-based movement | 4.6512 | 5 | yes |
| GO:1904064 | positive regulation of cation transmembrane transport | 4.6512 | 7 | yes |
| GO:0006813 | potassium ion transport | 3.4884 | 7 | yes |
| GO:0051259 | protein complex oligomerization | 3.4884 | 6 | yes |
| GO:0051260 | protein homooligomerization | 3.4884 | 7 | yes |
| GO:0061337 | cardiac conduction | 3.4884 | 7 | yes |
| GO:0071805 | potassium ion transmembrane transport | 3.4884 | 5 | yes |
| GO:0086091 | regulation of heart rate by cardiac conduction | 3.4884 | 4 | yes |
| GO:1901381 | positive regulation of potassium ion transmembrane transport | 3.4884 | 7 | yes |
| GO:1990573 | potassium ion import across plasma membrane | 3.4884 | 6 | yes |
| GO:0001508 | action potential | 2.3256 | 4 | yes |
| GO:0014819 | regulation of skeletal muscle contraction | 2.3256 | 8 | yes |
| GO:0014861 | regulation of skeletal muscle contraction via regulation of action potential | 2.3256 | 4 | yes |
| GO:0015693 | magnesium ion transport | 2.3256 | 7 | yes |
| GO:0030007 | intracellular potassium ion homeostasis | 2.3256 | 5 | yes |
| GO:0051262 | protein tetramerization | 2.3256 | 7 | yes |
| GO:0051289 | protein homotetramerization | 2.3256 | 8 | yes |
| GO:0051899 | membrane depolarization | 2.3256 | 4 | yes |
| GO:0055075 | potassium ion homeostasis | 2.3256 | 4 | yes |
| GO:0055119 | relaxation of cardiac muscle | 2.3256 | 5 | yes |
| GO:0060075 | regulation of resting membrane potential | 2.3256 | 4 | yes |
| GO:0086001 | cardiac muscle cell action potential | 2.3256 | 5 | yes |
| GO:0086002 | cardiac muscle cell action potential involved in contraction | 2.3256 | 6 | yes |
| GO:0086009 | membrane repolarization | 2.3256 | 4 | yes |
| GO:0086010 | membrane depolarization during action potential | 2.3256 | 5 | yes |
| GO:0086011 | membrane repolarization during action potential | 2.3256 | 5 | yes |
| GO:0086012 | membrane depolarization during cardiac muscle cell action potential | 2.3256 | 6 | yes |
| GO:0086013 | membrane repolarization during cardiac muscle cell action potential | 2.3256 | 6 | yes |
| GO:0090075 | relaxation of muscle | 2.3256 | 4 | yes |
| GO:0090076 | relaxation of skeletal muscle | 2.3256 | 5 | yes |
| GO:0099622 | cardiac muscle cell membrane repolarization | 2.3256 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNJ2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FLNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCN5A_HUMAN | [view interactions] | Low throughput | no | no |
| KAPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRAK2_HUMAN | [view interactions] | Low throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAV3_HUMAN | [view interactions] | Low throughput | no | no |
| IL16_HUMAN | [view interactions] | High throughput | no | no |
| SC22A_HUMAN | [view interactions] | High throughput | no | no |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AR13B_HUMAN | [view interactions] | High throughput | no | yes |
| KCJ18_HUMAN | [view interactions] | High throughput | no | no |
| KCJ15_HUMAN | [view interactions] | High throughput | no | yes |
| CAHD1_HUMAN | [view interactions] | High throughput | no | no |
| S19A1_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCAP_HUMAN | [view interactions] | High throughput | no | yes |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S20A2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFY16_HUMAN | [view interactions] | High throughput | no | yes |
| ZFYV9_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT5_HUMAN | [view interactions] | High throughput | no | yes |
| SRP54_HUMAN | [view interactions] | High throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPY4_HUMAN | [view interactions] | High throughput | no | yes |
| STAM1_HUMAN | [view interactions] | High throughput | no | yes |
| S12A4_HUMAN | [view interactions] | High throughput | no | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| S12A6_HUMAN | [view interactions] | High throughput | no | yes |
| NMT1_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NACA2_HUMAN | [view interactions] | High throughput | no | no |
| K319L_HUMAN | [view interactions] | High throughput | no | yes |
| NACAM_HUMAN | [view interactions] | High throughput | no | no |
| ZN622_HUMAN | [view interactions] | High throughput | no | yes |
| TM1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| MPRI_HUMAN | [view interactions] | High throughput | no | yes |
| KCNJ8_HUMAN | [view interactions] | High throughput | no | yes |
| GGA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNS_HUMAN | [view interactions] | High throughput | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP13B_HUMAN | [view interactions] | High throughput | no | no |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1AR_HUMAN | [view interactions] | High throughput | no | yes |
| BT3L4_HUMAN | [view interactions] | High throughput | no | yes |
| ELAP2_HUMAN | [view interactions] | High throughput | no | no |
| GGA1_HUMAN | [view interactions] | High throughput | no | yes |
| TRIPB_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM214_HUMAN | [view interactions] | High throughput | no | no |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA35_HUMAN | [view interactions] | High throughput | no | yes |
| NAA15_HUMAN | [view interactions] | High throughput | no | yes |
| UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEN3_HUMAN | [view interactions] | High throughput | no | yes |
| PSD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLRT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI26B_HUMAN | [view interactions] | High throughput | no | yes |
| DCBD1_HUMAN | [view interactions] | High throughput | no | no |
| PALS2_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGQ_HUMAN | [view interactions] | High throughput | no | yes |
| EFNB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAR6B_HUMAN | [view interactions] | High throughput | no | no |
| KI26A_HUMAN | [view interactions] | High throughput | no | no |
| PRRT4_HUMAN | [view interactions] | High throughput | no | no |
| FARP2_HUMAN | [view interactions] | High throughput | no | yes |
| LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JAM1_HUMAN | [view interactions] | High throughput | no | yes |
| DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KC1G2_HUMAN | [view interactions] | High throughput | no | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITAV_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
| GRIN3_HUMAN | [view interactions] | High throughput | no | yes |
| ANR26_HUMAN | [view interactions] | High throughput | no | yes |
| PLD1_HUMAN | [view interactions] | High throughput | no | no |
| EFR3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAI14_HUMAN | [view interactions] | High throughput | no | yes |
| SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA3_HUMAN | [view interactions] | High throughput | no | yes |
| ITA6_HUMAN | [view interactions] | High throughput | no | yes |
| FA83B_HUMAN | [view interactions] | High throughput | no | no |
| AGRL1_HUMAN | [view interactions] | High throughput | no | no |
| NIBA2_HUMAN | [view interactions] | High throughput | no | no |
| MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PALM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MALD2_HUMAN | [view interactions] | High throughput | no | yes |
| EFR3B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITA2_HUMAN | [view interactions] | High throughput | no | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA1_HUMAN | [view interactions] | High throughput | no | yes |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPZL1_HUMAN | [view interactions] | High throughput | no | yes |
| JAM3_HUMAN | [view interactions] | High throughput | no | no |
| CBARP_HUMAN | [view interactions] | High throughput | no | no |
| F1711_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BORG5_HUMAN | [view interactions] | High throughput | no | yes |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| CD166_HUMAN | [view interactions] | High throughput | no | no |
| FRS2_HUMAN | [view interactions] | High throughput | no | no |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S39AA_HUMAN | [view interactions] | High throughput | no | no |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C2C4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NOTC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILDR2_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASIC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPHB4_HUMAN | [view interactions] | High throughput | no | yes |
| S39A6_HUMAN | [view interactions] | High throughput | no | yes |
| RELL1_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| TMM51_HUMAN | [view interactions] | High throughput | no | yes |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLVC1_HUMAN | [view interactions] | High throughput | no | yes |
| UNC5B_HUMAN | [view interactions] | High throughput | no | yes |
| CTR1_HUMAN | [view interactions] | High throughput | no | no |
| LSR_HUMAN | [view interactions] | High throughput | no | yes |
| UNC5C_HUMAN | [view interactions] | High throughput | no | no |
| THSD1_HUMAN | [view interactions] | High throughput | no | no |
| KCNJ4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLPP3_HUMAN | [view interactions] | High throughput | no | no |
| CNNM3_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S39AE_HUMAN | [view interactions] | High throughput | no | yes |
| NECT2_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| CEIP2_HUMAN | [view interactions] | High throughput | no | yes |
| S12A7_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| DEP1B_HUMAN | [view interactions] | High throughput | no | yes |
| ADAM9_HUMAN | [view interactions] | High throughput | no | no |
| S38A2_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F171B_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSC2_HUMAN | [view interactions] | High throughput | no | no |
| SHB_HUMAN | [view interactions] | High throughput | no | yes |
| SDC3_HUMAN | [view interactions] | High throughput | no | yes |
| STK38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMPB_HUMAN | [view interactions] | High throughput | no | yes |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LFG1_HUMAN | [view interactions] | High throughput | no | yes |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| FILA2_HUMAN | [view interactions] | High throughput | no | no |
| UBE4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MA1B1_HUMAN | [view interactions] | High throughput | no | yes |
| CO3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CND1_HUMAN | [view interactions] | High throughput | no | yes |
| DCD_HUMAN | [view interactions] | High throughput | no | no |
| HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
| ROCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |