Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TM1L2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Probable role in protein transport. May regulate growth factor-induced mitogenic signaling. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in TM1L2_HUMAN
GO:0019900 kinase binding 32.1429 4 yes
GO:0019901 protein kinase binding 28.5714 5 yes
GO:0003723 RNA binding 25.0000 4 no
GO:0043169 cation binding 25.0000 4 no
GO:0046872 metal ion binding 25.0000 5 no
GO:0003779 actin binding 21.4286 4 no
GO:0043130 ubiquitin binding 14.2857 4 yes
GO:0035091 phosphatidylinositol binding 7.1429 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in TM1L2_HUMAN
GO:0048522 positive regulation of cellular process 60.7143 4 no
GO:0060255 regulation of macromolecule metabolic process 53.5714 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0051049 regulation of transport 50.0000 4 no
GO:0048523 negative regulation of cellular process 46.4286 4 yes
GO:0051128 regulation of cellular component organization 46.4286 4 yes
GO:0008104 protein localization 42.8571 4 yes
GO:0010646 regulation of cell communication 42.8571 4 no
GO:0031323 regulation of cellular metabolic process 39.2857 4 no
GO:0051246 regulation of protein metabolic process 39.2857 5 no
GO:0009893 positive regulation of metabolic process 39.2857 4 no
GO:0051726 regulation of cell cycle 35.7143 4 yes
GO:0071702 organic substance transport 35.7143 4 yes
GO:0071705 nitrogen compound transport 35.7143 4 yes
GO:0009892 negative regulation of metabolic process 35.7143 4 no
GO:0010605 negative regulation of macromolecule metabolic process 35.7143 5 no
GO:0009966 regulation of signal transduction 35.7143 4 no
GO:0015031 protein transport 32.1429 4 yes
GO:0031324 negative regulation of cellular metabolic process 32.1429 5 no
GO:0051050 positive regulation of transport 32.1429 4 no
GO:0010604 positive regulation of macromolecule metabolic process 32.1429 5 no
GO:0051247 positive regulation of protein metabolic process 32.1429 6 no
GO:1902531 regulation of intracellular signal transduction 32.1429 5 no
GO:0010564 regulation of cell cycle process 28.5714 5 yes
GO:0009057 macromolecule catabolic process 28.5714 4 no
GO:0006886 intracellular protein transport 28.5714 4 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0034762 regulation of transmembrane transport 28.5714 4 no
GO:0009889 regulation of biosynthetic process 25.0000 4 no
GO:0098657 import into cell 25.0000 4 no
GO:0022607 cellular component assembly 25.0000 4 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0010959 regulation of metal ion transport 25.0000 6 no
GO:0031325 positive regulation of cellular metabolic process 25.0000 5 no
GO:0043269 regulation of monoatomic ion transport 25.0000 5 no
GO:0009967 positive regulation of signal transduction 25.0000 5 no
GO:0048584 positive regulation of response to stimulus 25.0000 4 no
GO:0010556 regulation of macromolecule biosynthetic process 21.4286 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.4286 5 no
GO:0031326 regulation of cellular biosynthetic process 21.4286 5 no
GO:0036211 protein modification process 21.4286 4 no
GO:0043412 macromolecule modification 21.4286 4 no
GO:0051252 regulation of RNA metabolic process 21.4286 5 no
GO:0006508 proteolysis 21.4286 4 no
GO:0006996 organelle organization 21.4286 4 no
GO:0019941 modification-dependent protein catabolic process 21.4286 6 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0043632 modification-dependent macromolecule catabolic process 21.4286 5 no
GO:0051603 proteolysis involved in protein catabolic process 21.4286 5 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0001934 positive regulation of protein phosphorylation 21.4286 8 no
GO:0010038 response to metal ion 21.4286 4 no
GO:0010562 positive regulation of phosphorus metabolic process 21.4286 6 no
GO:0019220 regulation of phosphate metabolic process 21.4286 6 no
GO:0034765 regulation of monoatomic ion transmembrane transport 21.4286 5 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0043549 regulation of kinase activity 21.4286 5 no
GO:0045859 regulation of protein kinase activity 21.4286 6 no
GO:0045937 positive regulation of phosphate metabolic process 21.4286 7 no
GO:0051174 regulation of phosphorus metabolic process 21.4286 5 no
GO:0051248 negative regulation of protein metabolic process 21.4286 6 no
GO:0051338 regulation of transferase activity 21.4286 4 no
GO:1904062 regulation of monoatomic cation transmembrane transport 21.4286 6 no
GO:0022898 regulation of transmembrane transporter activity 21.4286 4 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 21.4286 5 no
GO:0033043 regulation of organelle organization 17.8571 5 yes
GO:0007346 regulation of mitotic cell cycle 7.1429 5 yes
GO:0051129 negative regulation of cellular component organization 7.1429 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MYO6_HUMAN [view entry] [view interactions] Low throughput yes no
TOLIP_HUMAN [view entry] [view interactions] Low throughput yes yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
LAPM5_HUMAN [view interactions] High throughput no yes
NDUA6_HUMAN [view interactions] High throughput no no
CUED1_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
GIPC1_HUMAN [view entry] [view interactions] High throughput yes yes
WBP2_HUMAN [view interactions] High throughput no yes
FAM9B_HUMAN [view interactions] High throughput no no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
SZRD1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
DZIP3_HUMAN [view interactions] High throughput no yes
RIGI_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
UBQL2_HUMAN [view interactions] High throughput no yes
CREB1_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
OVOL2_HUMAN [view interactions] High throughput no no
BAP1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
SAHH2_HUMAN [view entry] [view interactions] High throughput yes yes
LAGE3_HUMAN [view interactions] High throughput no yes
IGBP1_HUMAN [view interactions] High throughput no yes
ST1A1_HUMAN [view interactions] High throughput no no
RCN1_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
S10A4_HUMAN [view entry] [view interactions] High throughput yes no
DEST_HUMAN [view entry] [view interactions] High throughput yes yes
DFFA_HUMAN [view interactions] High throughput no yes
SAE2_HUMAN [view interactions] High throughput no yes
S10A6_HUMAN [view interactions] High throughput no yes
SRXN1_HUMAN [view interactions] High throughput no no
SERPH_HUMAN [view interactions] High throughput no no
GDE_HUMAN [view entry] [view interactions] High throughput yes no
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
UBE2N_HUMAN [view entry] [view interactions] High throughput yes yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
DBLOH_HUMAN [view interactions] High throughput no no
RN183_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CXD3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
PTN23_HUMAN [view entry] [view interactions] High throughput yes yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no