GDE_HUMAN
Evidence for PS localization
Functions
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GDE_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 27.2727 | 4 | no |
| GO:0016758 | hexosyltransferase activity | 13.6364 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GDE_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 40.9091 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 36.3636 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 36.3636 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 36.3636 | 4 | no |
| GO:0009057 | macromolecule catabolic process | 36.3636 | 4 | yes |
| GO:0010646 | regulation of cell communication | 36.3636 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 31.8182 | 4 | no |
| GO:0036211 | protein modification process | 31.8182 | 4 | no |
| GO:0043412 | macromolecule modification | 31.8182 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 31.8182 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 31.8182 | 4 | no |
| GO:0032880 | regulation of protein localization | 27.2727 | 5 | no |
| GO:0051049 | regulation of transport | 27.2727 | 4 | no |
| GO:0060341 | regulation of cellular localization | 27.2727 | 4 | no |
| GO:0071702 | organic substance transport | 27.2727 | 4 | no |
| GO:0071705 | nitrogen compound transport | 27.2727 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 27.2727 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.2727 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.2727 | 5 | no |
| GO:0008104 | protein localization | 27.2727 | 4 | no |
| GO:0009966 | regulation of signal transduction | 27.2727 | 4 | no |
| GO:0010468 | regulation of gene expression | 27.2727 | 5 | no |
| GO:0015031 | protein transport | 27.2727 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.7273 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.7273 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.7273 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 22.7273 | 6 | no |
| GO:0006996 | organelle organization | 22.7273 | 4 | no |
| GO:0030162 | regulation of proteolysis | 22.7273 | 6 | no |
| GO:0015980 | energy derivation by oxidation of organic compounds | 22.7273 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 22.7273 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 22.7273 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 22.7273 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 22.7273 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.7273 | 4 | no |
| GO:0005976 | polysaccharide metabolic process | 18.1818 | 4 | yes |
| GO:0005977 | glycogen metabolic process | 18.1818 | 6 | yes |
| GO:0006073 | cellular glucan metabolic process | 18.1818 | 5 | yes |
| GO:0006112 | energy reserve metabolic process | 18.1818 | 5 | yes |
| GO:0014070 | response to organic cyclic compound | 18.1818 | 4 | yes |
| GO:0031667 | response to nutrient levels | 18.1818 | 4 | yes |
| GO:0044042 | glucan metabolic process | 18.1818 | 5 | yes |
| GO:0044264 | cellular polysaccharide metabolic process | 18.1818 | 4 | yes |
| GO:0000272 | polysaccharide catabolic process | 13.6364 | 5 | yes |
| GO:0005980 | glycogen catabolic process | 13.6364 | 6 | yes |
| GO:0009251 | glucan catabolic process | 13.6364 | 6 | yes |
| GO:0016052 | carbohydrate catabolic process | 13.6364 | 4 | yes |
| GO:0033993 | response to lipid | 13.6364 | 4 | yes |
| GO:0044247 | cellular polysaccharide catabolic process | 13.6364 | 5 | yes |
| GO:0044275 | cellular carbohydrate catabolic process | 13.6364 | 4 | yes |
| GO:0000271 | polysaccharide biosynthetic process | 9.0909 | 5 | yes |
| GO:0005978 | glycogen biosynthetic process | 9.0909 | 7 | yes |
| GO:0009059 | macromolecule biosynthetic process | 9.0909 | 4 | yes |
| GO:0009250 | glucan biosynthetic process | 9.0909 | 6 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 9.0909 | 4 | yes |
| GO:0031960 | response to corticosteroid | 9.0909 | 5 | yes |
| GO:0033692 | cellular polysaccharide biosynthetic process | 9.0909 | 5 | yes |
| GO:0034637 | cellular carbohydrate biosynthetic process | 9.0909 | 4 | yes |
| GO:0034645 | cellular macromolecule biosynthetic process | 9.0909 | 4 | yes |
| GO:0048545 | response to steroid hormone | 9.0909 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NHLC1_HUMAN | [view interactions] | Low throughput | no | no |
| UVRAG_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RASF5_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB2_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| PPR3B_HUMAN | [view interactions] | High throughput | no | yes |
| STBD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAD3_HUMAN | [view interactions] | High throughput | no | yes |
| M3K6_HUMAN | [view interactions] | High throughput | no | yes |
| PHKG2_HUMAN | [view interactions] | High throughput | no | no |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| AAKG1_HUMAN | [view interactions] | High throughput | no | no |
| CDK5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FASTK_HUMAN | [view interactions] | High throughput | no | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXA2_HUMAN | [view interactions] | High throughput | no | no |
| ACSL1_HUMAN | [view interactions] | High throughput | no | no |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASB3_HUMAN | [view interactions] | High throughput | no | yes |
| ASB15_HUMAN | [view interactions] | High throughput | no | no |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN126_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TNS2_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| ARI2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| PYGB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLYG2_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| LGUL_HUMAN | [view interactions] | High throughput | no | yes |
| TKFC_HUMAN | [view interactions] | High throughput | no | no |
| BCAT1_HUMAN | [view interactions] | High throughput | no | no |
| TRUA_HUMAN | [view interactions] | High throughput | no | yes |
| GDN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SP100_HUMAN | [view interactions] | High throughput | no | no |
| VPS25_HUMAN | [view interactions] | High throughput | no | yes |
| PURA2_HUMAN | [view interactions] | High throughput | no | yes |
| ASPC1_HUMAN | [view interactions] | High throughput | no | yes |
| DEOC_HUMAN | [view interactions] | High throughput | no | no |
| GARS_HUMAN | [view interactions] | High throughput | no | yes |
| HXK4_HUMAN | [view interactions] | High throughput | no | yes |
| KHK_HUMAN | [view interactions] | High throughput | no | no |
| MA2B1_HUMAN | [view interactions] | High throughput | no | yes |
| MCFD2_HUMAN | [view interactions] | High throughput | no | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| PSB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| SPT20_HUMAN | [view interactions] | High throughput | no | yes |
| ST1E1_HUMAN | [view interactions] | High throughput | no | no |
| TM1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| NNRD_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSH1_HUMAN | [view interactions] | High throughput | no | yes |
| GRHPR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PYGL_HUMAN | [view interactions] | Computational | no | yes |
| LYAG_HUMAN | [view interactions] | Computational | no | yes |
| ENPP3_HUMAN | [view interactions] | Computational | no | no |
| MGAL_HUMAN | [view interactions] | Computational | no | no |
| PYGM_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SGPL1_HUMAN | [view interactions] | Computational | no | yes |
| GYS2_HUMAN | [view interactions] | Computational | no | no |
| MGA_HUMAN | [view interactions] | Computational | no | no |
| SCN9A_HUMAN | [view interactions] | Computational | no | yes |
| NOP53_HUMAN | [view interactions] | Computational | no | yes |
| MPV17_HUMAN | [view interactions] | Computational | no | no |
| GLGB_HUMAN | [view interactions] | Computational | no | yes |
| PGM2L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GYS1_HUMAN | [view interactions] | Computational | no | yes |
| AMY2B_HUMAN | [view interactions] | Computational | no | no |
| UGPA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PGM2_HUMAN | [view interactions] | Computational | no | no |
| GLYG_HUMAN | [view interactions] | Computational | no | yes |