DP13A_HUMAN
Evidence for PS localization
Functions
Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism (PubMed, PubMed, PubMed, PubMed, PubMed). Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex (PubMed). Functions as a positive regulator of innate immune response via activation of AKT1 signaling pathway by forming a complex with APPL1 and PIK3R1 . Inhibits Fc-gamma receptor-mediated phagocytosis through PI3K/Akt signaling in macrophages . Regulates TLR4 signaling in activated macrophages . Involved in trafficking of the TGFBR1 from the endosomes to the nucleus via microtubules in a TRAF6-dependent manner (PubMed). Plays a role in cell metabolism by regulating adiponecting and insulin signaling pathways (PubMed, PubMed, PubMed). Required for fibroblast migration through HGF cell signaling . Positive regulator of beta-catenin/TCF-dependent transcription through direct interaction with RUVBL2/reptin resulting in the relief of RUVBL2-mediated repression of beta-catenin/TCF target genes by modulating the interactions within the beta-catenin-reptin-HDAC complex (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002063 | LIG_OCRL_FandH_1 | LIG | 403 | 415 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DP13A_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 34.8485 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 34.8485 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.8485 | 4 | no |
| GO:0019900 | kinase binding | 24.2424 | 4 | yes |
| GO:0019901 | protein kinase binding | 24.2424 | 5 | yes |
| GO:0046872 | metal ion binding | 22.7273 | 4 | no |
| GO:0005524 | ATP binding | 22.7273 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 22.7273 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.7273 | 5 | no |
| GO:0042803 | protein homodimerization activity | 15.1515 | 4 | yes |
| GO:0035091 | phosphatidylinositol binding | 12.1212 | 4 | yes |
| GO:0015631 | tubulin binding | 10.6061 | 4 | yes |
| GO:0043422 | protein kinase B binding | 3.0303 | 6 | yes |
| GO:0048487 | beta-tubulin binding | 3.0303 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DP13A_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 68.1818 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 62.1212 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 57.5758 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 57.5758 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 56.0606 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 54.5455 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.5455 | 4 | yes |
| GO:0010646 | regulation of cell communication | 53.0303 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 51.5152 | 4 | yes |
| GO:0008104 | protein localization | 48.4848 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 46.9697 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 46.9697 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 43.9394 | 5 | no |
| GO:0010468 | regulation of gene expression | 42.4242 | 5 | yes |
| GO:0071702 | organic substance transport | 40.9091 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 40.9091 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 40.9091 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 40.9091 | 5 | yes |
| GO:0051049 | regulation of transport | 37.8788 | 4 | yes |
| GO:0015031 | protein transport | 37.8788 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 36.3636 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 36.3636 | 5 | yes |
| GO:0010941 | regulation of cell death | 34.8485 | 4 | no |
| GO:0006886 | intracellular protein transport | 34.8485 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
| GO:0031399 | regulation of protein modification process | 33.3333 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.8182 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 31.8182 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.8182 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.8182 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.3030 | 5 | yes |
| GO:0006996 | organelle organization | 30.3030 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 30.3030 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 30.3030 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 30.3030 | 4 | no |
| GO:0071310 | cellular response to organic substance | 28.7879 | 4 | yes |
| GO:0022607 | cellular component assembly | 28.7879 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.7879 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.7879 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.7879 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 28.7879 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 28.7879 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.7879 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 28.7879 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 28.7879 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.7879 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 27.2727 | 4 | no |
| GO:0051050 | positive regulation of transport | 25.7576 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 25.7576 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 25.7576 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.7576 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 25.7576 | 7 | no |
| GO:0033043 | regulation of organelle organization | 25.7576 | 5 | no |
| GO:0060341 | regulation of cellular localization | 24.2424 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 24.2424 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.2424 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 24.2424 | 7 | no |
| GO:2000026 | regulation of multicellular organismal development | 24.2424 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.7273 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.7273 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.7273 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.7273 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 22.7273 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.7273 | 7 | no |
| GO:0051094 | positive regulation of developmental process | 22.7273 | 4 | no |
| GO:0060284 | regulation of cell development | 22.7273 | 5 | no |
| GO:0060548 | negative regulation of cell death | 22.7273 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.7273 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.7273 | 6 | yes |
| GO:0034762 | regulation of transmembrane transport | 22.7273 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 22.7273 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 21.2121 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 21.2121 | 5 | no |
| GO:0030030 | cell projection organization | 21.2121 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 21.2121 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 21.2121 | 7 | no |
| GO:0051338 | regulation of transferase activity | 21.2121 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 21.2121 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 21.2121 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 21.2121 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 21.2121 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 19.6970 | 4 | yes |
| GO:0032880 | regulation of protein localization | 19.6970 | 5 | yes |
| GO:0080134 | regulation of response to stress | 18.1818 | 4 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 18.1818 | 4 | yes |
| GO:2000145 | regulation of cell motility | 16.6667 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 16.6667 | 5 | yes |
| GO:0010628 | positive regulation of gene expression | 16.6667 | 6 | yes |
| GO:0030334 | regulation of cell migration | 16.6667 | 5 | yes |
| GO:0070848 | response to growth factor | 15.1515 | 4 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 15.1515 | 5 | yes |
| GO:0051051 | negative regulation of transport | 13.6364 | 4 | yes |
| GO:0010564 | regulation of cell cycle process | 13.6364 | 5 | yes |
| GO:0030100 | regulation of endocytosis | 13.6364 | 5 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 13.6364 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 12.1212 | 4 | yes |
| GO:0033365 | protein localization to organelle | 12.1212 | 5 | yes |
| GO:1905475 | regulation of protein localization to membrane | 10.6061 | 6 | yes |
| GO:0001817 | regulation of cytokine production | 10.6061 | 4 | yes |
| GO:0007346 | regulation of mitotic cell cycle | 10.6061 | 5 | yes |
| GO:0050776 | regulation of immune response | 10.6061 | 4 | yes |
| GO:0051169 | nuclear transport | 9.0909 | 4 | yes |
| GO:0006913 | nucleocytoplasmic transport | 9.0909 | 5 | yes |
| GO:0008286 | insulin receptor signaling pathway | 9.0909 | 6 | yes |
| GO:0034504 | protein localization to nucleus | 9.0909 | 6 | yes |
| GO:0045807 | positive regulation of endocytosis | 9.0909 | 5 | yes |
| GO:0051170 | import into nucleus | 7.5758 | 6 | yes |
| GO:0072594 | establishment of protein localization to organelle | 7.5758 | 4 | yes |
| GO:1901987 | regulation of cell cycle phase transition | 7.5758 | 6 | yes |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 7.5758 | 6 | yes |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 7.5758 | 7 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 7.5758 | 6 | yes |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 7.5758 | 7 | yes |
| GO:0001819 | positive regulation of cytokine production | 7.5758 | 5 | yes |
| GO:0002683 | negative regulation of immune system process | 7.5758 | 4 | yes |
| GO:0006606 | protein import into nucleus | 7.5758 | 5 | yes |
| GO:0010827 | regulation of glucose transmembrane transport | 7.5758 | 5 | yes |
| GO:0046324 | regulation of glucose import | 7.5758 | 6 | yes |
| GO:1903076 | regulation of protein localization to plasma membrane | 6.0606 | 7 | yes |
| GO:0002697 | regulation of immune effector process | 6.0606 | 4 | yes |
| GO:0010762 | regulation of fibroblast migration | 6.0606 | 6 | yes |
| GO:0010828 | positive regulation of glucose transmembrane transport | 6.0606 | 6 | yes |
| GO:0019221 | cytokine-mediated signaling pathway | 6.0606 | 4 | yes |
| GO:0035728 | response to hepatocyte growth factor | 6.0606 | 5 | yes |
| GO:0035729 | cellular response to hepatocyte growth factor stimulus | 6.0606 | 6 | yes |
| GO:0046326 | positive regulation of glucose import | 6.0606 | 7 | yes |
| GO:0050764 | regulation of phagocytosis | 6.0606 | 5 | yes |
| GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway | 4.5455 | 5 | yes |
| GO:0062207 | regulation of pattern recognition receptor signaling pathway | 4.5455 | 5 | yes |
| GO:1900015 | regulation of cytokine production involved in inflammatory response | 4.5455 | 5 | yes |
| GO:1900376 | regulation of secondary metabolite biosynthetic process | 4.5455 | 5 | yes |
| GO:1900378 | positive regulation of secondary metabolite biosynthetic process | 4.5455 | 6 | yes |
| GO:1905301 | regulation of macropinocytosis | 4.5455 | 7 | yes |
| GO:1905303 | positive regulation of macropinocytosis | 4.5455 | 7 | yes |
| GO:1905449 | regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | 4.5455 | 5 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 4.5455 | 4 | yes |
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 4.5455 | 5 | yes |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 4.5455 | 6 | yes |
| GO:0031347 | regulation of defense response | 4.5455 | 5 | yes |
| GO:0033211 | adiponectin-activated signaling pathway | 4.5455 | 4 | yes |
| GO:0034121 | regulation of toll-like receptor signaling pathway | 4.5455 | 6 | yes |
| GO:0034143 | regulation of toll-like receptor 4 signaling pathway | 4.5455 | 7 | yes |
| GO:0043455 | regulation of secondary metabolic process | 4.5455 | 4 | yes |
| GO:0045088 | regulation of innate immune response | 4.5455 | 5 | yes |
| GO:0048021 | regulation of melanin biosynthetic process | 4.5455 | 6 | yes |
| GO:0048023 | positive regulation of melanin biosynthetic process | 4.5455 | 7 | yes |
| GO:0048548 | regulation of pinocytosis | 4.5455 | 6 | yes |
| GO:0048549 | positive regulation of pinocytosis | 4.5455 | 6 | yes |
| GO:1900017 | positive regulation of cytokine production involved in inflammatory response | 3.0303 | 6 | yes |
| GO:1905450 | negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | 3.0303 | 6 | yes |
| GO:0002698 | negative regulation of immune effector process | 3.0303 | 5 | yes |
| GO:0050765 | negative regulation of phagocytosis | 3.0303 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DP13A_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 4.5455 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 4.5455 | 5 | no |
| DOID:114 | heart disease | 4.5455 | 3 | no |
| DOID:331 | central nervous system disease | 4.5455 | 3 | no |
| DOID:12377 | spinal muscular atrophy | 3.0303 | 6 | no |
| DOID:1289 | neurodegenerative disease | 3.0303 | 4 | no |
| DOID:231 | motor neuron disease | 3.0303 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PAQR1_HUMAN | [view interactions] | Low throughput | no | no |
| DP13A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DP13B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HDAC2_HUMAN | [view interactions] | Low throughput | no | yes |
| HDAC3_HUMAN | [view interactions] | Low throughput | no | yes |
| PAQR2_HUMAN | [view interactions] | Low throughput | no | yes |
| RAB21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTA2_HUMAN | [view interactions] | Low throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| OCRL_HUMAN | [view interactions] | Low throughput | no | yes |
| P66B_HUMAN | [view interactions] | Low throughput | no | yes |
| MBD3_HUMAN | [view interactions] | Low throughput | no | yes |
| RBBP4_HUMAN | [view interactions] | Low throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | Low throughput | no | no |
| EGF_HUMAN | [view interactions] | Low throughput | no | no |
| LRP2_HUMAN | [view interactions] | Low throughput | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TGFA1_HUMAN | [view interactions] | Low throughput | no | no |
| AKT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DCC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FSHR_HUMAN | [view interactions] | Low throughput | no | no |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | Low throughput | no | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LPAR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REBL1_HUMAN | [view interactions] | High throughput | no | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| F167A_HUMAN | [view interactions] | High throughput | no | yes |
| TPC2_HUMAN | [view interactions] | High throughput | no | no |
| ZN830_HUMAN | [view interactions] | High throughput | no | yes |
| GIPC2_HUMAN | [view interactions] | High throughput | no | yes |
| I5P2_HUMAN | [view interactions] | High throughput | no | yes |
| RB22A_HUMAN | [view interactions] | High throughput | no | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| CKLF4_HUMAN | [view interactions] | High throughput | no | yes |
| RTCB_HUMAN | [view interactions] | High throughput | no | yes |
| KLF15_HUMAN | [view interactions] | High throughput | no | yes |
| BATF3_HUMAN | [view interactions] | High throughput | no | no |
| SH22A_HUMAN | [view interactions] | High throughput | no | no |
| IN80E_HUMAN | [view interactions] | High throughput | no | yes |
| ZN829_HUMAN | [view interactions] | High throughput | no | no |
| DOK7_HUMAN | [view interactions] | High throughput | no | yes |
| CBLB_HUMAN | [view interactions] | High throughput | no | yes |
| ID1_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SCAPE_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| SYFM_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA9_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| MEOX1_HUMAN | [view interactions] | High throughput | no | no |
| MTND_HUMAN | [view interactions] | High throughput | no | yes |
| PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| GDE_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANKR1_HUMAN | [view interactions] | High throughput | no | no |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DACT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC3_HUMAN | [view interactions] | High throughput | no | no |
| DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIPC_HUMAN | [view interactions] | High throughput | no | no |
| LUC7L_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH3_HUMAN | [view interactions] | High throughput | no | no |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| C1T9A_HUMAN | [view interactions] | High throughput | no | no |
| DYSF_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RXRB_HUMAN | [view interactions] | High throughput | no | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K1_HUMAN | [view interactions] | High throughput | no | yes |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| EPHA5_HUMAN | [view interactions] | High throughput | no | no |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIFCL_HUMAN | [view interactions] | High throughput | no | yes |
| BRWD1_HUMAN | [view interactions] | High throughput | no | yes |
| DOK3_HUMAN | [view interactions] | High throughput | no | no |
| MAGC3_HUMAN | [view interactions] | High throughput | no | no |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHAF1_HUMAN | [view interactions] | High throughput | no | yes |
| KLHL2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| NRSN1_HUMAN | [view interactions] | High throughput | no | yes |
| RP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| DTX3L_HUMAN | [view interactions] | High throughput | no | yes |
| M4A10_HUMAN | [view interactions] | High throughput | no | no |
| GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AQP9_HUMAN | [view interactions] | High throughput | no | no |
| F133A_HUMAN | [view interactions] | High throughput | no | no |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAMP3_HUMAN | [view interactions] | High throughput | no | no |
| MARF1_HUMAN | [view interactions] | High throughput | no | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL14E_HUMAN | [view interactions] | High throughput | no | yes |
| ARL3_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPC11_HUMAN | [view interactions] | High throughput | no | no |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| RELCH_HUMAN | [view interactions] | High throughput | no | yes |
| TTC4_HUMAN | [view interactions] | High throughput | no | yes |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| CASP9_HUMAN | [view interactions] | Computational | no | yes |
| ADIPO_HUMAN | [view interactions] | Computational | no | no |