Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DPYL5_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May have a function in neuronal differentiation and/or axon growth. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DPYL5_HUMAN
GO:0015631 tubulin binding 28.0000 4 yes
GO:0019900 kinase binding 24.0000 4 no
GO:0017076 purine nucleotide binding 24.0000 4 no
GO:0032555 purine ribonucleotide binding 24.0000 4 no
GO:0035639 purine ribonucleoside triphosphate binding 24.0000 4 no
GO:0008017 microtubule binding 20.0000 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DPYL5_HUMAN
GO:0048522 positive regulation of cellular process 68.0000 4 no
GO:0051128 regulation of cellular component organization 64.0000 4 no
GO:0010646 regulation of cell communication 48.0000 4 no
GO:0048523 negative regulation of cellular process 48.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 48.0000 4 no
GO:0030030 cell projection organization 44.0000 4 yes
GO:0120036 plasma membrane bounded cell projection organization 44.0000 5 yes
GO:0051171 regulation of nitrogen compound metabolic process 44.0000 4 no
GO:0080090 regulation of primary metabolic process 44.0000 4 no
GO:0071310 cellular response to organic substance 44.0000 4 no
GO:0009893 positive regulation of metabolic process 40.0000 4 no
GO:0009966 regulation of signal transduction 40.0000 4 no
GO:0051049 regulation of transport 40.0000 4 no
GO:0051246 regulation of protein metabolic process 40.0000 5 no
GO:0008104 protein localization 40.0000 4 no
GO:0051130 positive regulation of cellular component organization 40.0000 5 no
GO:0031175 neuron projection development 36.0000 6 yes
GO:0010604 positive regulation of macromolecule metabolic process 36.0000 5 no
GO:0031323 regulation of cellular metabolic process 36.0000 4 no
GO:0044087 regulation of cellular component biogenesis 36.0000 4 no
GO:0010468 regulation of gene expression 32.0000 5 no
GO:0010941 regulation of cell death 32.0000 4 no
GO:0042981 regulation of apoptotic process 32.0000 6 no
GO:0043067 regulation of programmed cell death 32.0000 5 no
GO:0051050 positive regulation of transport 32.0000 4 no
GO:0031344 regulation of cell projection organization 32.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 32.0000 6 no
GO:0006996 organelle organization 32.0000 4 no
GO:0009889 regulation of biosynthetic process 28.0000 4 no
GO:0009892 negative regulation of metabolic process 28.0000 4 no
GO:0009968 negative regulation of signal transduction 28.0000 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.0000 5 no
GO:0010648 negative regulation of cell communication 28.0000 5 no
GO:0023057 negative regulation of signaling 28.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 28.0000 5 no
GO:0031399 regulation of protein modification process 28.0000 6 no
GO:0048585 negative regulation of response to stimulus 28.0000 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 28.0000 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 28.0000 5 no
GO:0032880 regulation of protein localization 28.0000 5 no
GO:0060341 regulation of cellular localization 28.0000 4 no
GO:0022607 cellular component assembly 28.0000 4 no
GO:0051129 negative regulation of cellular component organization 28.0000 5 no
GO:0010556 regulation of macromolecule biosynthetic process 24.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 24.0000 5 no
GO:0043066 negative regulation of apoptotic process 24.0000 7 no
GO:0043069 negative regulation of programmed cell death 24.0000 6 no
GO:0051247 positive regulation of protein metabolic process 24.0000 6 no
GO:0060548 negative regulation of cell death 24.0000 5 no
GO:1902531 regulation of intracellular signal transduction 24.0000 5 no
GO:0015031 protein transport 24.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 24.0000 5 no
GO:0071702 organic substance transport 24.0000 4 no
GO:0071705 nitrogen compound transport 24.0000 4 no
GO:0031346 positive regulation of cell projection organization 24.0000 6 no
GO:0050804 modulation of chemical synaptic transmission 24.0000 5 no
GO:0099177 regulation of trans-synaptic signaling 24.0000 4 no
GO:0043933 protein-containing complex organization 24.0000 4 no
GO:0007399 nervous system development 20.0000 4 yes
GO:0097485 neuron projection guidance 20.0000 7 yes
GO:0007411 axon guidance 16.0000 8 yes

Disease

Term Name % Distance from top the of the tree Annotated in DPYL5_HUMAN
DOID:331 central nervous system disease 8.0000 3 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DPYL5_HUMAN [view entry] [view interactions] Low throughput yes yes
DPYS_HUMAN [view interactions] Low throughput no no
DPYL2_HUMAN [view entry] [view interactions] Low throughput yes yes
DPYL3_HUMAN [view entry] [view interactions] Low throughput yes yes
HAX1_HUMAN [view interactions] High throughput no no
DGUOK_HUMAN [view interactions] High throughput no yes
KTU_HUMAN [view interactions] High throughput no yes
FGL1_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
TAFA3_HUMAN [view interactions] High throughput no no
GLYC_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
VRK1_HUMAN [view interactions] High throughput no yes
MGDP1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
CHD4_HUMAN [view interactions] High throughput no yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
MMAB_HUMAN [view interactions] High throughput no yes
LRC41_HUMAN [view interactions] High throughput no no
CUL9_HUMAN [view interactions] High throughput no no
AP2D_HUMAN [view interactions] High throughput no no
ANTR2_HUMAN [view interactions] High throughput no no
CARM1_HUMAN [view interactions] High throughput no yes
PYRD_HUMAN [view interactions] High throughput no yes
ACTC_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
NUFP1_HUMAN [view interactions] High throughput no yes
TF2LY_HUMAN [view interactions] High throughput no no
LONF2_HUMAN [view interactions] High throughput no yes
SHIP2_HUMAN [view interactions] High throughput no yes
DPYL4_HUMAN [view entry] [view interactions] High throughput yes yes
KLDC3_HUMAN [view interactions] High throughput no yes
LEG7_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
SYDM_HUMAN [view interactions] High throughput no yes
CF161_HUMAN [view interactions] High throughput no yes
CASP6_HUMAN [view interactions] High throughput no no
FGFR3_HUMAN [view interactions] High throughput no yes
NMDE3_HUMAN [view entry] [view interactions] High throughput yes no
GELS_HUMAN [view entry] [view interactions] High throughput yes no
HIP1_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
PEX1_HUMAN [view interactions] High throughput no no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
KLF11_HUMAN [view interactions] High throughput no no
RNF11_HUMAN [view interactions] High throughput no yes
UBQL1_HUMAN [view interactions] High throughput no yes
COQ8A_HUMAN [view interactions] High throughput no no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
RAB36_HUMAN [view interactions] High throughput no no
RB40C_HUMAN [view interactions] High throughput no no
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
ARMC1_HUMAN [view interactions] High throughput no yes
PNMA2_HUMAN [view interactions] Computational no yes
FES_HUMAN [view entry] [view interactions] Computational yes no
SC6A5_HUMAN [view interactions] Computational no no
LGI1_HUMAN [view entry] [view interactions] Computational yes no
GSK3B_HUMAN [view entry] [view interactions] Computational yes yes
AMPH_HUMAN [view entry] [view interactions] Computational yes yes