WFS1_HUMAN
Evidence for PS localization
Functions
Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (PubMed). Negatively regulates the ER stress response and positively regulates the stability of V-ATPase subunits ATP6V1A and ATP1B1 by preventing their degradation through an unknown proteasome-independent mechanism (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000574 | MOD_N-GLC_1 | MOD | 27 | 32 | - |
| ELMI000575 | MOD_N-GLC_1 | MOD | 334 | 339 | - |
| ELMI000576 | MOD_N-GLC_1 | MOD | 499 | 504 | - |
| ELMI000577 | MOD_N-GLC_1 | MOD | 660 | 665 | - |
| ELMI000578 | MOD_N-GLC_1 | MOD | 745 | 750 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in WFS1_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 27.9412 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.5294 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0588 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.0588 | 4 | no |
| GO:0031625 | ubiquitin protein ligase binding | 7.3529 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 7.3529 | 4 | yes |
| GO:0051117 | ATPase binding | 2.9412 | 4 | yes |
| GO:0140297 | DNA-binding transcription factor binding | 2.9412 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in WFS1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 44.1176 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 36.7647 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 36.7647 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 33.8235 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 33.8235 | 4 | yes |
| GO:0010646 | regulation of cell communication | 32.3529 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 32.3529 | 4 | yes |
| GO:0051049 | regulation of transport | 32.3529 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 32.3529 | 4 | no |
| GO:0006996 | organelle organization | 30.8824 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 27.9412 | 4 | yes |
| GO:0008104 | protein localization | 27.9412 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.4706 | 5 | yes |
| GO:0022607 | cellular component assembly | 26.4706 | 4 | no |
| GO:0009966 | regulation of signal transduction | 25.0000 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.0000 | 5 | yes |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 23.5294 | 5 | yes |
| GO:0051050 | positive regulation of transport | 23.5294 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 23.5294 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 23.5294 | 5 | no |
| GO:0071705 | nitrogen compound transport | 22.0588 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 20.5882 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 20.5882 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.5882 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 20.5882 | 5 | yes |
| GO:0015031 | protein transport | 20.5882 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 20.5882 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 19.1176 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 19.1176 | 6 | yes |
| GO:0043269 | regulation of ion transport | 19.1176 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 19.1176 | 6 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 19.1176 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 17.6471 | 6 | yes |
| GO:0010243 | response to organonitrogen compound | 17.6471 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 17.6471 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 17.6471 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 17.6471 | 7 | yes |
| GO:0051252 | regulation of RNA metabolic process | 17.6471 | 5 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 17.6471 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 17.6471 | 6 | yes |
| GO:0010941 | regulation of cell death | 16.1765 | 4 | yes |
| GO:0048878 | chemical homeostasis | 16.1765 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 16.1765 | 5 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 14.7059 | 7 | yes |
| GO:0006873 | cellular ion homeostasis | 14.7059 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 14.7059 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 14.7059 | 4 | yes |
| GO:0030003 | cellular cation homeostasis | 14.7059 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 14.7059 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 14.7059 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 14.7059 | 4 | yes |
| GO:0050801 | ion homeostasis | 14.7059 | 5 | yes |
| GO:0055080 | cation homeostasis | 14.7059 | 6 | yes |
| GO:0098771 | inorganic ion homeostasis | 14.7059 | 6 | yes |
| GO:0006874 | cellular calcium ion homeostasis | 13.2353 | 7 | yes |
| GO:0006875 | cellular metal ion homeostasis | 13.2353 | 6 | yes |
| GO:0009968 | negative regulation of signal transduction | 13.2353 | 5 | yes |
| GO:0010959 | regulation of metal ion transport | 13.2353 | 6 | yes |
| GO:0043270 | positive regulation of ion transport | 13.2353 | 5 | yes |
| GO:0055065 | metal ion homeostasis | 13.2353 | 7 | yes |
| GO:0055074 | calcium ion homeostasis | 13.2353 | 8 | yes |
| GO:0060548 | negative regulation of cell death | 13.2353 | 5 | yes |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 13.2353 | 6 | yes |
| GO:0072507 | divalent inorganic cation homeostasis | 13.2353 | 7 | yes |
| GO:0009057 | macromolecule catabolic process | 11.7647 | 4 | yes |
| GO:0051924 | regulation of calcium ion transport | 11.7647 | 7 | yes |
| GO:0080134 | regulation of response to stress | 11.7647 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 11.7647 | 4 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 10.2941 | 5 | yes |
| GO:0030163 | protein catabolic process | 10.2941 | 4 | yes |
| GO:0043066 | negative regulation of apoptotic process | 10.2941 | 7 | yes |
| GO:0043069 | negative regulation of programmed cell death | 10.2941 | 6 | yes |
| GO:0045927 | positive regulation of growth | 10.2941 | 4 | yes |
| GO:0080135 | regulation of cellular response to stress | 10.2941 | 4 | yes |
| GO:0006508 | proteolysis | 8.8235 | 4 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 8.8235 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 8.8235 | 6 | yes |
| GO:0034976 | response to endoplasmic reticulum stress | 8.8235 | 4 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 8.8235 | 7 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 8.8235 | 6 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 8.8235 | 6 | yes |
| GO:0051928 | positive regulation of calcium ion transport | 8.8235 | 6 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 8.8235 | 6 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 8.8235 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 8.8235 | 8 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 7.3529 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 7.3529 | 5 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 7.3529 | 4 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 7.3529 | 5 | yes |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 5.8824 | 8 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 5.8824 | 7 | yes |
| GO:0010498 | proteasomal protein catabolic process | 5.8824 | 5 | yes |
| GO:0030433 | ubiquitin-dependent ERAD pathway | 5.8824 | 6 | yes |
| GO:0031396 | regulation of protein ubiquitination | 5.8824 | 8 | yes |
| GO:0032469 | endoplasmic reticulum calcium ion homeostasis | 5.8824 | 8 | yes |
| GO:0036503 | ERAD pathway | 5.8824 | 5 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 5.8824 | 6 | yes |
| GO:0050821 | protein stabilization | 5.8824 | 4 | yes |
| GO:1901214 | regulation of neuron death | 5.8824 | 5 | yes |
| GO:1901215 | negative regulation of neuron death | 5.8824 | 6 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 5.8824 | 7 | yes |
| GO:0033500 | carbohydrate homeostasis | 4.4118 | 5 | yes |
| GO:0042593 | glucose homeostasis | 4.4118 | 6 | yes |
| GO:0043523 | regulation of neuron apoptotic process | 4.4118 | 6 | yes |
| GO:0051604 | protein maturation | 4.4118 | 4 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 4.4118 | 5 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 4.4118 | 6 | yes |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 4.4118 | 6 | yes |
| GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 4.4118 | 7 | yes |
| GO:0001822 | kidney development | 2.9412 | 4 | yes |
| GO:0007600 | sensory perception | 2.9412 | 4 | yes |
| GO:0031398 | positive regulation of protein ubiquitination | 2.9412 | 9 | yes |
| GO:0043524 | negative regulation of neuron apoptotic process | 2.9412 | 7 | yes |
| GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 2.9412 | 8 | yes |
| GO:1905897 | regulation of response to endoplasmic reticulum stress | 2.9412 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in WFS1_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 4.4118 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 4.4118 | 5 | no |
| DOID:114 | heart disease | 4.4118 | 3 | no |
| DOID:0050155 | sensory system disease | 2.9412 | 3 | yes |
| DOID:0050563 | nonsyndromic deafness | 2.9412 | 5 | yes |
| DOID:2742 | auditory system disease | 2.9412 | 4 | yes |
| DOID:0060038 | specific developmental disorder | 2.9412 | 3 | no |
| DOID:1059 | intellectual disability | 2.9412 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.9412 | 6 | no |
| DOID:440 | neuromuscular disease | 2.9412 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.9412 | 3 | no |
| DOID:870 | neuropathy | 2.9412 | 4 | no |
| DOID:331 | central nervous system disease | 2.9412 | 3 | no |
| DOID:2843 | long QT syndrome | 2.9412 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| AT1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AT2A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SMUF1_HUMAN | [view interactions] | Low throughput | no | yes |
| ATF6A_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA5_HUMAN | [view interactions] | Low throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | Low throughput | no | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| PLPR1_HUMAN | [view interactions] | High throughput | no | no |
| PALMD_HUMAN | [view interactions] | High throughput | no | no |
| ESRP1_HUMAN | [view interactions] | High throughput | no | yes |
| ERC6L_HUMAN | [view interactions] | High throughput | no | yes |
| FBX42_HUMAN | [view interactions] | High throughput | no | yes |
| GFOD1_HUMAN | [view interactions] | High throughput | no | yes |
| MS18A_HUMAN | [view interactions] | High throughput | no | yes |
| PELO_HUMAN | [view interactions] | High throughput | no | yes |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| NCLN_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZF64B_HUMAN | [view interactions] | High throughput | no | no |
| G2E3_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| GGA2B_HUMAN | [view interactions] | High throughput | no | no |
| SMU1_HUMAN | [view interactions] | High throughput | no | yes |
| NUFP2_HUMAN | [view interactions] | High throughput | no | no |
| KCC1G_HUMAN | [view interactions] | High throughput | no | no |
| BRME1_HUMAN | [view interactions] | High throughput | no | yes |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| ASHWN_HUMAN | [view interactions] | High throughput | no | yes |
| DCR1B_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| ES8L2_HUMAN | [view interactions] | High throughput | no | yes |
| RUSF1_HUMAN | [view interactions] | High throughput | no | yes |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| ABCG4_HUMAN | [view interactions] | High throughput | no | no |
| PERP_HUMAN | [view interactions] | High throughput | no | no |
| DMRTA_HUMAN | [view interactions] | High throughput | no | no |
| GPSM3_HUMAN | [view interactions] | High throughput | no | no |
| BPEC1_HUMAN | [view interactions] | High throughput | no | no |
| SPP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PHF5A_HUMAN | [view interactions] | High throughput | no | yes |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AUGN_HUMAN | [view interactions] | High throughput | no | no |
| SARNP_HUMAN | [view interactions] | High throughput | no | yes |
| CMS1_HUMAN | [view interactions] | High throughput | no | yes |
| CG050_HUMAN | [view interactions] | High throughput | no | yes |
| WDR83_HUMAN | [view interactions] | High throughput | no | yes |
| SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAF1_HUMAN | [view interactions] | High throughput | no | no |
| LOXL4_HUMAN | [view interactions] | High throughput | no | no |
| CDCA7_HUMAN | [view interactions] | High throughput | no | no |
| RN208_HUMAN | [view interactions] | High throughput | no | no |
| SPY4_HUMAN | [view interactions] | High throughput | no | yes |
| TLR10_HUMAN | [view interactions] | High throughput | no | no |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PG12A_HUMAN | [view interactions] | High throughput | no | yes |
| SYNCI_HUMAN | [view interactions] | High throughput | no | no |
| DUS16_HUMAN | [view interactions] | High throughput | no | yes |
| ZN436_HUMAN | [view interactions] | High throughput | no | yes |
| THUM2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN696_HUMAN | [view interactions] | High throughput | no | no |
| TCAL4_HUMAN | [view interactions] | High throughput | no | no |
| FAKD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZXDC_HUMAN | [view interactions] | High throughput | no | no |
| FANK1_HUMAN | [view interactions] | High throughput | no | no |
| ZN697_HUMAN | [view interactions] | High throughput | no | no |
| TCAL8_HUMAN | [view interactions] | High throughput | no | no |
| BMF_HUMAN | [view interactions] | High throughput | no | yes |
| ZCRB1_HUMAN | [view interactions] | High throughput | no | no |
| MYLK2_HUMAN | [view interactions] | High throughput | no | no |
| SPF45_HUMAN | [view interactions] | High throughput | no | yes |
| DISP1_HUMAN | [view interactions] | High throughput | no | no |
| MPND_HUMAN | [view interactions] | High throughput | no | yes |
| FBH1_HUMAN | [view interactions] | High throughput | no | no |
| ZN497_HUMAN | [view interactions] | High throughput | no | no |
| ZN670_HUMAN | [view interactions] | High throughput | no | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| CX038_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| PRUN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH048_HUMAN | [view interactions] | High throughput | no | no |
| YIPF3_HUMAN | [view interactions] | High throughput | no | yes |
| MET27_HUMAN | [view interactions] | High throughput | no | yes |
| ANTR1_HUMAN | [view interactions] | High throughput | no | no |
| IQUB_HUMAN | [view interactions] | High throughput | no | no |
| PAQR1_HUMAN | [view interactions] | High throughput | no | no |
| F117B_HUMAN | [view interactions] | High throughput | no | no |
| LCA5L_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| SHLD1_HUMAN | [view interactions] | High throughput | no | yes |
| STA5A_HUMAN | [view interactions] | High throughput | no | no |
| SRARP_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| F163A_HUMAN | [view interactions] | High throughput | no | no |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| FA98C_HUMAN | [view interactions] | High throughput | no | yes |
| AQP6_HUMAN | [view interactions] | High throughput | no | no |
| ZN524_HUMAN | [view interactions] | High throughput | no | no |
| F209A_HUMAN | [view interactions] | High throughput | no | no |
| SPAT8_HUMAN | [view interactions] | High throughput | no | no |
| CD79A_HUMAN | [view interactions] | High throughput | no | no |
| TCP1L_HUMAN | [view interactions] | High throughput | no | no |
| TRI23_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VP37A_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA8_HUMAN | [view interactions] | High throughput | no | no |
| ZN572_HUMAN | [view interactions] | High throughput | no | yes |
| ASPG_HUMAN | [view interactions] | High throughput | no | yes |
| CA216_HUMAN | [view interactions] | High throughput | no | yes |
| PLIN2_HUMAN | [view interactions] | High throughput | no | no |
| ZNF57_HUMAN | [view interactions] | High throughput | no | no |
| AQP8_HUMAN | [view interactions] | High throughput | no | no |
| ZN440_HUMAN | [view interactions] | High throughput | no | no |
| KDSR_HUMAN | [view interactions] | High throughput | no | yes |
| KT222_HUMAN | [view interactions] | High throughput | no | no |
| VATB1_HUMAN | [view interactions] | High throughput | no | no |
| BAP18_HUMAN | [view interactions] | High throughput | no | yes |
| FANCG_HUMAN | [view interactions] | High throughput | no | yes |
| ISCA2_HUMAN | [view interactions] | High throughput | no | yes |
| FABP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASCL4_HUMAN | [view interactions] | High throughput | no | no |
| EYA3_HUMAN | [view interactions] | High throughput | no | no |
| UB2J2_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TET5B_HUMAN | [view interactions] | High throughput | no | no |
| DVL3_HUMAN | [view interactions] | High throughput | no | yes |
| MR1L1_HUMAN | [view interactions] | High throughput | no | no |
| DNM3A_HUMAN | [view interactions] | High throughput | no | yes |
| LENG8_HUMAN | [view interactions] | High throughput | no | yes |
| DNSL1_HUMAN | [view interactions] | High throughput | no | yes |
| RHPN1_HUMAN | [view interactions] | High throughput | no | yes |
| TIM8A_HUMAN | [view interactions] | High throughput | no | yes |
| PGRP3_HUMAN | [view interactions] | High throughput | no | no |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| SCAM4_HUMAN | [view interactions] | High throughput | no | yes |
| CYTA_HUMAN | [view interactions] | High throughput | no | no |
| MOFA1_HUMAN | [view interactions] | High throughput | no | yes |
| COMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN791_HUMAN | [view interactions] | High throughput | no | yes |
| KCRU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRA81_HUMAN | [view interactions] | High throughput | no | no |
| KIF1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RN168_HUMAN | [view interactions] | High throughput | no | no |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S6OS1_HUMAN | [view interactions] | High throughput | no | no |
| FRIL_HUMAN | [view interactions] | High throughput | no | yes |
| MAGBI_HUMAN | [view interactions] | High throughput | no | no |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CC141_HUMAN | [view interactions] | High throughput | no | no |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| RUAS1_HUMAN | [view interactions] | High throughput | no | no |
| G6PC1_HUMAN | [view interactions] | High throughput | no | no |
| OXLA_HUMAN | [view interactions] | High throughput | no | no |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| BACD1_HUMAN | [view interactions] | High throughput | no | no |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| LNX2_HUMAN | [view interactions] | High throughput | no | yes |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRE2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K6_HUMAN | [view interactions] | High throughput | no | yes |
| TMM61_HUMAN | [view interactions] | High throughput | no | no |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| FAM9A_HUMAN | [view interactions] | High throughput | no | no |
| DPOLB_HUMAN | [view interactions] | High throughput | no | yes |
| ZN366_HUMAN | [view interactions] | High throughput | no | yes |
| PER1_HUMAN | [view interactions] | High throughput | no | no |
| VSX2_HUMAN | [view interactions] | High throughput | no | no |
| PABP3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN774_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| KR197_HUMAN | [view interactions] | High throughput | no | no |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| KR133_HUMAN | [view interactions] | High throughput | no | no |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| H3C_HUMAN | [view interactions] | High throughput | no | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LHX8_HUMAN | [view interactions] | High throughput | no | no |
| LCAT_HUMAN | [view interactions] | High throughput | no | no |
| FAM74_HUMAN | [view interactions] | High throughput | no | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEX19_HUMAN | [view interactions] | High throughput | no | no |
| STT3A_HUMAN | [view interactions] | High throughput | no | yes |
| IQCF2_HUMAN | [view interactions] | High throughput | no | no |
| KT33B_HUMAN | [view interactions] | High throughput | no | no |
| F111B_HUMAN | [view interactions] | High throughput | no | no |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| GP141_HUMAN | [view interactions] | High throughput | no | no |
| IBP4_HUMAN | [view interactions] | High throughput | no | no |
| LCE2A_HUMAN | [view interactions] | High throughput | no | no |
| IG2R_HUMAN | [view interactions] | High throughput | no | no |
| LCE1B_HUMAN | [view interactions] | High throughput | no | no |
| DNJC4_HUMAN | [view interactions] | High throughput | no | yes |
| SAMD7_HUMAN | [view interactions] | High throughput | no | no |
| HXK3_HUMAN | [view interactions] | High throughput | no | no |
| PKHG7_HUMAN | [view interactions] | High throughput | no | no |
| UBE2K_HUMAN | [view interactions] | High throughput | no | yes |
| SYCE3_HUMAN | [view interactions] | High throughput | no | no |
| HHEX_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLI4_HUMAN | [view interactions] | High throughput | no | no |
| CENPR_HUMAN | [view interactions] | High throughput | no | yes |
| ISK2_HUMAN | [view interactions] | High throughput | no | no |
| DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DEN2B_HUMAN | [view interactions] | High throughput | no | yes |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKIL_HUMAN | [view interactions] | High throughput | no | yes |
| LT4R2_HUMAN | [view interactions] | High throughput | no | no |
| LYAM2_HUMAN | [view interactions] | High throughput | no | no |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| SDC2_HUMAN | [view interactions] | High throughput | no | yes |
| CLC11_HUMAN | [view interactions] | High throughput | no | no |
| TARG1_HUMAN | [view interactions] | High throughput | no | no |
| S100P_HUMAN | [view interactions] | High throughput | no | no |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS15A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYPD3_HUMAN | [view interactions] | High throughput | no | no |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| P2RX2_HUMAN | [view interactions] | High throughput | no | no |
| PSMD5_HUMAN | [view interactions] | High throughput | no | yes |
| UB2L6_HUMAN | [view interactions] | High throughput | no | no |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H31_HUMAN | [view interactions] | High throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ZN239_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| FOSL1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| GPAN1_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BSND_HUMAN | [view interactions] | High throughput | no | no |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| ZN225_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| ZSC9_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| ZKSC8_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| ZSC26_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| ZN138_HUMAN | [view interactions] | High throughput | no | no |
| CKLF5_HUMAN | [view interactions] | High throughput | no | yes |
| ZN124_HUMAN | [view interactions] | High throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYY1_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| CLGN_HUMAN | [view interactions] | High throughput | no | no |
| TNNI3_HUMAN | [view interactions] | High throughput | no | no |
| TTMP_HUMAN | [view interactions] | High throughput | no | no |
| TDG_HUMAN | [view interactions] | High throughput | no | yes |
| EFNA4_HUMAN | [view interactions] | High throughput | no | no |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNPC3_HUMAN | [view interactions] | High throughput | no | no |
| TNR9_HUMAN | [view interactions] | High throughput | no | no |
| NALD2_HUMAN | [view interactions] | High throughput | no | yes |
| PBIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRDL_HUMAN | [view interactions] | High throughput | no | yes |
| CD3E_HUMAN | [view interactions] | High throughput | no | no |
| NR1D2_HUMAN | [view interactions] | High throughput | no | yes |
| AA2BR_HUMAN | [view interactions] | High throughput | no | no |
| RNF10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
| KLK8_HUMAN | [view interactions] | High throughput | no | no |
| K0408_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| PUM1_HUMAN | [view interactions] | High throughput | no | yes |
| GPR84_HUMAN | [view interactions] | High throughput | no | no |
| EPN4_HUMAN | [view interactions] | High throughput | no | yes |
| STR3N_HUMAN | [view interactions] | High throughput | no | yes |
| IF2P_HUMAN | [view interactions] | High throughput | no | yes |
| OPALI_HUMAN | [view interactions] | High throughput | no | yes |
| FEZ2_HUMAN | [view interactions] | High throughput | no | yes |
| RAMP3_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| T184A_HUMAN | [view interactions] | High throughput | no | no |
| TBPL1_HUMAN | [view interactions] | High throughput | no | yes |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| CRIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM72_HUMAN | [view interactions] | High throughput | no | no |
| CSN2_HUMAN | [view interactions] | High throughput | no | yes |
| TMEM9_HUMAN | [view interactions] | High throughput | no | no |
| RB11B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P2RY8_HUMAN | [view interactions] | High throughput | no | no |
| CCNE2_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| MOT7_HUMAN | [view interactions] | High throughput | no | no |
| TM231_HUMAN | [view interactions] | High throughput | no | yes |
| S13A2_HUMAN | [view interactions] | High throughput | no | no |
| GP173_HUMAN | [view interactions] | High throughput | no | no |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| HUMMR_HUMAN | [view interactions] | High throughput | no | yes |
| I18RA_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| JMJD7_HUMAN | [view interactions] | High throughput | no | yes |
| DHC24_HUMAN | [view interactions] | High throughput | no | yes |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| C5AR1_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3F_HUMAN | [view interactions] | High throughput | no | yes |
| ACKR2_HUMAN | [view interactions] | High throughput | no | no |
| CITE2_HUMAN | [view interactions] | High throughput | no | yes |
| TYOBP_HUMAN | [view interactions] | High throughput | no | no |
| RXLT1_HUMAN | [view interactions] | High throughput | no | no |
| VIPR2_HUMAN | [view interactions] | High throughput | no | no |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| TI17B_HUMAN | [view interactions] | High throughput | no | no |
| CY24A_HUMAN | [view interactions] | High throughput | no | no |
| KCMB2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| UBAC1_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX2_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMF2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APC13_HUMAN | [view interactions] | High throughput | no | no |
| TBL2_HUMAN | [view interactions] | High throughput | no | no |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAP_HUMAN | [view interactions] | High throughput | no | yes |
| HYPM_HUMAN | [view interactions] | High throughput | no | no |
| CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| B2L13_HUMAN | [view interactions] | High throughput | no | no |
| GNA11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLC1_HUMAN | [view interactions] | High throughput | no | no |
| CLCA1_HUMAN | [view interactions] | High throughput | no | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LPIN1_HUMAN | [view interactions] | High throughput | no | no |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| SEPT6_HUMAN | [view interactions] | High throughput | no | yes |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| TCF25_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLIK3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| GALT6_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| NUDT4_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESM1_HUMAN | [view interactions] | High throughput | no | no |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| SERC3_HUMAN | [view interactions] | High throughput | no | yes |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| MS3L1_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| YIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| RAI2_HUMAN | [view interactions] | High throughput | no | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| CNPY3_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPC6_HUMAN | [view interactions] | High throughput | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| BATF_HUMAN | [view interactions] | High throughput | no | no |
| FBLN5_HUMAN | [view interactions] | High throughput | no | no |
| UB2E3_HUMAN | [view interactions] | High throughput | no | yes |
| C1D_HUMAN | [view interactions] | High throughput | no | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| EDRF1_HUMAN | [view interactions] | High throughput | no | no |
| LHX6_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FBX4_HUMAN | [view interactions] | High throughput | no | no |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| CIA2B_HUMAN | [view interactions] | High throughput | no | yes |
| GPHRB_HUMAN | [view interactions] | High throughput | no | no |
| RT17_HUMAN | [view interactions] | High throughput | no | yes |
| KLF3_HUMAN | [view interactions] | High throughput | no | yes |
| ING4_HUMAN | [view interactions] | High throughput | no | no |
| KAD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLRS_HUMAN | [view interactions] | High throughput | no | no |
| NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
| KLF15_HUMAN | [view interactions] | High throughput | no | yes |
| KLH20_HUMAN | [view interactions] | High throughput | no | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| ATF6B_HUMAN | [view interactions] | Computational | no | yes |
| TM38A_HUMAN | [view interactions] | Computational | no | yes |
| ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| XBP1_HUMAN | [view interactions] | Computational | no | no |
| CISD2_HUMAN | [view interactions] | Computational | no | yes |