CHIP_HUMAN
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at Lys-41, Lys-61 and Lys-81, thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and promotes ubiquitin-mediated protein degradation (PubMed). Negatively regulates the suppressive function of regulatory T-cells (Treg) during inflammation by mediating the ubiquitination and degradation of FOXP3 in a HSPA1A/B-dependent manner (PubMed). Likely mediates polyubiquitination and downregulates plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Negatively regulates TGF-beta signaling by modulating the basal level of SMAD3 via ubiquitin-mediated degradation (PubMed). May regulate myosin assembly in striated muscles together with UBE4B and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (PubMed). Mediates ubiquitination of RIPK3 leading to its subsequent proteasome-dependent degradation (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in CHIP_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 36.2637 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 34.0659 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 32.9670 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 30.7692 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 28.5714 | 5 | no |
GO:0005524 | ATP binding | 27.4725 | 5 | no |
GO:0046872 | metal ion binding | 21.9780 | 4 | no |
GO:0019900 | kinase binding | 20.8791 | 4 | yes |
GO:0003723 | RNA binding | 20.3297 | 4 | no |
GO:0031625 | ubiquitin protein ligase binding | 19.2308 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 19.2308 | 4 | yes |
GO:0042803 | protein homodimerization activity | 9.8901 | 4 | yes |
GO:0001664 | G protein-coupled receptor binding | 7.6923 | 4 | yes |
GO:0048156 | tau protein binding | 6.5934 | 4 | yes |
GO:0004842 | ubiquitin-protein transferase activity | 6.0440 | 4 | yes |
GO:0030544 | Hsp70 protein binding | 5.4945 | 4 | yes |
GO:0051879 | Hsp90 protein binding | 3.2967 | 4 | yes |
GO:0061630 | ubiquitin protein ligase activity | 2.7473 | 5 | yes |
GO:0061659 | ubiquitin-like protein ligase activity | 2.7473 | 4 | yes |
GO:0030911 | TPR domain binding | 2.1978 | 4 | yes |
GO:0034450 | ubiquitin-ubiquitin ligase activity | 1.6484 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in CHIP_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 63.1868 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 63.1868 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 62.0879 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 62.0879 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 57.1429 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 48.9011 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 48.3516 | 4 | yes |
GO:0010646 | regulation of cell communication | 47.8022 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 46.7033 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 46.1538 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 44.5055 | 5 | yes |
GO:0009966 | regulation of signal transduction | 43.9560 | 4 | yes |
GO:0010468 | regulation of gene expression | 42.3077 | 5 | no |
GO:0051128 | regulation of cellular component organization | 42.3077 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.1099 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 40.1099 | 5 | yes |
GO:0009889 | regulation of biosynthetic process | 39.5604 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 39.5604 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 37.9121 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 36.2637 | 6 | yes |
GO:0006996 | organelle organization | 36.2637 | 4 | no |
GO:0010941 | regulation of cell death | 34.6154 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 33.5165 | 5 | no |
GO:0042981 | regulation of apoptotic process | 33.5165 | 6 | no |
GO:0043067 | regulation of programmed cell death | 33.5165 | 5 | no |
GO:0031399 | regulation of protein modification process | 33.5165 | 6 | yes |
GO:0036211 | protein modification process | 33.5165 | 4 | yes |
GO:0043412 | macromolecule modification | 33.5165 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 32.9670 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 32.9670 | 5 | no |
GO:0071310 | cellular response to organic substance | 32.4176 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 32.4176 | 4 | no |
GO:0051049 | regulation of transport | 32.4176 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 31.8681 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 30.7692 | 6 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 30.7692 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 30.7692 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 30.7692 | 6 | no |
GO:0010647 | positive regulation of cell communication | 28.5714 | 5 | no |
GO:0023056 | positive regulation of signaling | 28.5714 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 28.0220 | 5 | no |
GO:0080134 | regulation of response to stress | 26.9231 | 4 | no |
GO:0022607 | cellular component assembly | 26.9231 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 26.3736 | 5 | no |
GO:0008104 | protein localization | 25.8242 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 25.8242 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 25.8242 | 5 | no |
GO:0010648 | negative regulation of cell communication | 25.8242 | 5 | yes |
GO:0023057 | negative regulation of signaling | 25.8242 | 4 | yes |
GO:0031401 | positive regulation of protein modification process | 25.2747 | 7 | yes |
GO:0044087 | regulation of cellular component biogenesis | 25.2747 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 25.2747 | 4 | yes |
GO:0051050 | positive regulation of transport | 24.7253 | 4 | no |
GO:0009894 | regulation of catabolic process | 24.7253 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 24.7253 | 4 | yes |
GO:0051248 | negative regulation of protein metabolic process | 24.1758 | 6 | no |
GO:0009968 | negative regulation of signal transduction | 23.6264 | 5 | yes |
GO:0030162 | regulation of proteolysis | 23.6264 | 6 | yes |
GO:0051130 | positive regulation of cellular component organization | 23.6264 | 5 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 23.0769 | 4 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.0769 | 6 | no |
GO:0009891 | positive regulation of biosynthetic process | 22.5275 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 22.5275 | 6 | no |
GO:0042325 | regulation of phosphorylation | 22.5275 | 7 | no |
GO:0010243 | response to organonitrogen compound | 22.5275 | 4 | yes |
GO:0060548 | negative regulation of cell death | 21.9780 | 5 | no |
GO:0051338 | regulation of transferase activity | 21.4286 | 4 | yes |
GO:0060341 | regulation of cellular localization | 21.4286 | 4 | no |
GO:0071702 | organic substance transport | 21.4286 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 21.4286 | 4 | no |
GO:0033043 | regulation of organelle organization | 21.4286 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 21.4286 | 7 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.8791 | 6 | no |
GO:0071705 | nitrogen compound transport | 20.8791 | 4 | no |
GO:0051336 | regulation of hydrolase activity | 20.8791 | 4 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 20.3297 | 6 | no |
GO:0043066 | negative regulation of apoptotic process | 20.3297 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 20.3297 | 6 | no |
GO:0080135 | regulation of cellular response to stress | 20.3297 | 4 | no |
GO:0009057 | macromolecule catabolic process | 20.3297 | 4 | yes |
GO:0090304 | nucleic acid metabolic process | 19.2308 | 4 | yes |
GO:0031329 | regulation of cellular catabolic process | 19.2308 | 5 | yes |
GO:0044265 | cellular macromolecule catabolic process | 17.0330 | 4 | yes |
GO:0051347 | positive regulation of transferase activity | 16.4835 | 5 | yes |
GO:1903320 | regulation of protein modification by small protein conjugation or removal | 16.4835 | 7 | yes |
GO:0006508 | proteolysis | 16.4835 | 4 | yes |
GO:0042176 | regulation of protein catabolic process | 15.9341 | 5 | yes |
GO:0045862 | positive regulation of proteolysis | 15.9341 | 7 | yes |
GO:0009896 | positive regulation of catabolic process | 15.3846 | 5 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 15.3846 | 5 | yes |
GO:0051603 | proteolysis involved in protein catabolic process | 14.8352 | 5 | yes |
GO:0070647 | protein modification by small protein conjugation or removal | 14.8352 | 5 | yes |
GO:0019941 | modification-dependent protein catabolic process | 14.8352 | 6 | yes |
GO:0031396 | regulation of protein ubiquitination | 14.8352 | 8 | yes |
GO:0043632 | modification-dependent macromolecule catabolic process | 14.8352 | 5 | yes |
GO:1901565 | organonitrogen compound catabolic process | 14.2857 | 4 | yes |
GO:0032446 | protein modification by small protein conjugation | 13.7363 | 6 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 13.7363 | 5 | yes |
GO:0016567 | protein ubiquitination | 13.1868 | 7 | yes |
GO:0006511 | ubiquitin-dependent protein catabolic process | 12.6374 | 7 | yes |
GO:0030163 | protein catabolic process | 12.6374 | 4 | yes |
GO:1903050 | regulation of proteolysis involved in protein catabolic process | 12.0879 | 7 | yes |
GO:0031331 | positive regulation of cellular catabolic process | 12.0879 | 6 | yes |
GO:0061136 | regulation of proteasomal protein catabolic process | 10.4396 | 6 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 9.8901 | 4 | yes |
GO:0010498 | proteasomal protein catabolic process | 9.8901 | 5 | yes |
GO:0031334 | positive regulation of protein-containing complex assembly | 9.8901 | 6 | yes |
GO:0043393 | regulation of protein binding | 9.8901 | 4 | yes |
GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 9.3407 | 6 | yes |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 9.3407 | 6 | yes |
GO:0045732 | positive regulation of protein catabolic process | 9.3407 | 6 | yes |
GO:0006259 | DNA metabolic process | 8.7912 | 4 | yes |
GO:0006974 | cellular response to DNA damage stimulus | 8.7912 | 4 | yes |
GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 8.2418 | 8 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 8.2418 | 5 | yes |
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 7.6923 | 7 | yes |
GO:0035967 | cellular response to topologically incorrect protein | 7.6923 | 4 | yes |
GO:1901800 | positive regulation of proteasomal protein catabolic process | 7.1429 | 7 | yes |
GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 7.1429 | 8 | yes |
GO:0034976 | response to endoplasmic reticulum stress | 7.1429 | 4 | yes |
GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 6.5934 | 7 | yes |
GO:0031398 | positive regulation of protein ubiquitination | 6.5934 | 9 | yes |
GO:0034605 | cellular response to heat | 6.5934 | 4 | yes |
GO:0036293 | response to decreased oxygen levels | 6.5934 | 4 | yes |
GO:0000209 | protein polyubiquitination | 6.0440 | 8 | yes |
GO:0019216 | regulation of lipid metabolic process | 6.0440 | 5 | yes |
GO:0051100 | negative regulation of binding | 6.0440 | 4 | yes |
GO:0006281 | DNA repair | 5.4945 | 5 | yes |
GO:0032091 | negative regulation of protein binding | 5.4945 | 5 | yes |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 5.4945 | 8 | yes |
GO:0036503 | ERAD pathway | 5.4945 | 5 | yes |
GO:0071453 | cellular response to oxygen levels | 4.9451 | 4 | yes |
GO:0030433 | ubiquitin-dependent ERAD pathway | 4.9451 | 6 | yes |
GO:0036294 | cellular response to decreased oxygen levels | 4.9451 | 5 | yes |
GO:0051438 | regulation of ubiquitin-protein transferase activity | 4.3956 | 5 | yes |
GO:0090287 | regulation of cellular response to growth factor stimulus | 4.3956 | 4 | yes |
GO:0070534 | protein K63-linked ubiquitination | 3.8462 | 9 | yes |
GO:0071456 | cellular response to hypoxia | 3.8462 | 4 | yes |
GO:0090092 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 3.8462 | 5 | yes |
GO:0038127 | ERBB signaling pathway | 3.8462 | 6 | yes |
GO:0051604 | protein maturation | 3.2967 | 4 | yes |
GO:0061684 | chaperone-mediated autophagy | 2.7473 | 4 | yes |
GO:0090101 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 2.7473 | 6 | yes |
GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus | 2.7473 | 5 | yes |
GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway | 2.7473 | 6 | yes |
GO:0051443 | positive regulation of ubiquitin-protein transferase activity | 2.1978 | 6 | yes |
GO:0006515 | protein quality control for misfolded or incompletely synthesized proteins | 2.1978 | 6 | yes |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 2.1978 | 7 | yes |
GO:0051865 | protein autoubiquitination | 1.6484 | 8 | yes |
GO:0019218 | regulation of steroid metabolic process | 1.6484 | 6 | yes |
GO:0038128 | ERBB2 signaling pathway | 1.6484 | 7 | yes |
GO:0051788 | response to misfolded protein | 1.0989 | 4 | yes |
GO:0071218 | cellular response to misfolded protein | 1.0989 | 5 | yes |
GO:0090034 | regulation of chaperone-mediated protein complex assembly | 1.0989 | 6 | yes |
GO:0090035 | positive regulation of chaperone-mediated protein complex assembly | 1.0989 | 7 | yes |
GO:0030579 | ubiquitin-dependent SMAD protein catabolic process | 1.0989 | 8 | yes |
GO:0031943 | regulation of glucocorticoid metabolic process | 1.0989 | 5 | yes |
GO:0032350 | regulation of hormone metabolic process | 1.0989 | 4 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in CHIP_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 3.8462 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 3.8462 | 5 | no |
DOID:114 | heart disease | 3.8462 | 3 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 3.2967 | 6 | no |
DOID:440 | neuromuscular disease | 3.2967 | 5 | no |
DOID:574 | peripheral nervous system disease | 3.2967 | 3 | no |
DOID:870 | neuropathy | 3.2967 | 4 | no |
DOID:1289 | neurodegenerative disease | 2.7473 | 4 | no |
DOID:331 | central nervous system disease | 2.7473 | 3 | no |
DOID:0050686 | organ system cancer | 2.1978 | 3 | no |
DOID:12930 | dilated cardiomyopathy | 2.1978 | 6 | no |
DOID:2843 | long QT syndrome | 1.6484 | 6 | no |
DOID:12377 | spinal muscular atrophy | 1.6484 | 6 | no |
DOID:231 | motor neuron disease | 1.6484 | 5 | no |
DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.6484 | 7 | no |
DOID:0080000 | muscular disease | 1.6484 | 3 | no |
DOID:423 | myopathy | 1.6484 | 5 | no |
DOID:66 | muscle tissue disease | 1.6484 | 4 | no |
DOID:0050542 | Charcot-Marie-Tooth disease type X | 1.0989 | 7 | no |
DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 1.0989 | 7 | no |
DOID:0111206 | distal hereditary motor neuronopathy type 2 | 1.0989 | 8 | no |
DOID:120 | female reproductive organ cancer | 1.0989 | 5 | no |
DOID:193 | reproductive organ cancer | 1.0989 | 4 | no |
DOID:6457 | Cowden syndrome | 1.0989 | 3 | no |
DOID:0050890 | synucleinopathy | 1.0989 | 5 | no |
DOID:0060894 | early-onset Parkinsons disease | 1.0989 | 7 | no |
DOID:14330 | Parkinsons disease | 1.0989 | 6 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
MEN1_HUMAN | [view interactions] | Low throughput | no | yes |
FBX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P73_HUMAN | [view interactions] | Low throughput | no | no |
ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PSMD4_HUMAN | [view interactions] | Low throughput | no | yes |
RUNX1_HUMAN | [view interactions] | Low throughput | no | yes |
FOXO1_HUMAN | [view interactions] | Low throughput | no | yes |
GCYB1_HUMAN | [view interactions] | Low throughput | no | yes |
MAST1_HUMAN | [view interactions] | Low throughput | no | yes |
GCYA1_HUMAN | [view interactions] | Low throughput | no | yes |
CYBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DAXX_HUMAN | [view interactions] | Low throughput | no | yes |
ACVR1_HUMAN | [view interactions] | Low throughput | no | yes |
ERR1_HUMAN | [view interactions] | Low throughput | no | yes |
SMAD5_HUMAN | [view interactions] | Low throughput | no | no |
BMAL1_HUMAN | [view interactions] | Low throughput | no | yes |
NQO1_HUMAN | [view interactions] | Low throughput | no | no |
CLOCK_HUMAN | [view interactions] | Low throughput | no | yes |
IRF1_HUMAN | [view interactions] | Low throughput | no | yes |
ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
TLR4_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
NRK_HUMAN | [view interactions] | Low throughput | no | no |
KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MYCD_HUMAN | [view interactions] | Low throughput | no | yes |
HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SMAD4_HUMAN | [view interactions] | Low throughput | no | yes |
SGK1_HUMAN | [view interactions] | Low throughput | no | yes |
CD4_HUMAN | [view interactions] | Low throughput | no | no |
DRD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
V2R_HUMAN | [view interactions] | Low throughput | no | no |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TFE2_HUMAN | [view interactions] | Low throughput | no | no |
CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
SKP2_HUMAN | [view interactions] | Low throughput | no | yes |
MYC_HUMAN | [view interactions] | Low throughput | no | yes |
TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
APR_HUMAN | [view interactions] | Low throughput | no | yes |
GHR_HUMAN | [view interactions] | Low throughput | no | yes |
PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UB2D3_HUMAN | [view interactions] | Low throughput | no | yes |
ATLA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DNJA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MZF1_HUMAN | [view interactions] | Low throughput | no | yes |
CREM_HUMAN | [view interactions] | Low throughput | no | no |
MK07_HUMAN | [view interactions] | Low throughput | no | yes |
NHLC1_HUMAN | [view interactions] | Low throughput | no | no |
SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
MKKS_HUMAN | [view interactions] | Low throughput | no | yes |
IREB2_HUMAN | [view interactions] | Low throughput | no | no |
HPBP1_HUMAN | [view interactions] | Low throughput | no | yes |
OTUD3_HUMAN | [view interactions] | Low throughput | no | yes |
PSMD1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PSA3_HUMAN | [view interactions] | Low throughput | no | no |
HS71B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MIF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DPM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TERT_HUMAN | [view interactions] | Low throughput | no | no |
IKZF1_HUMAN | [view interactions] | Low throughput | no | no |
UB2Q1_HUMAN | [view interactions] | Low throughput | no | no |
CFTR_HUMAN | [view interactions] | Low throughput | no | no |
ATCAY_HUMAN | [view interactions] | Low throughput | no | no |
DNJC5_HUMAN | [view interactions] | Low throughput | no | yes |
NOS2_HUMAN | [view interactions] | Low throughput | no | yes |
M3K2_HUMAN | [view interactions] | Low throughput | no | yes |
MET_HUMAN | [view interactions] | Low throughput | no | yes |
HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SMG5_HUMAN | [view interactions] | Low throughput | no | no |
HSF1_HUMAN | [view interactions] | Low throughput | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HSP76_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
NOX5_HUMAN | [view interactions] | Low throughput | no | no |
ILK_HUMAN | [view interactions] | Low throughput | no | no |
CAR11_HUMAN | [view interactions] | Low throughput | no | no |
M3K7_HUMAN | [view interactions] | Low throughput | no | yes |
BAG1_HUMAN | [view interactions] | Low throughput | no | yes |
IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
BAG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MALT1_HUMAN | [view interactions] | Low throughput | no | no |
BAG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
S10A2_HUMAN | [view interactions] | Low throughput | no | no |
S10A6_HUMAN | [view interactions] | Low throughput | no | yes |
S100P_HUMAN | [view interactions] | Low throughput | no | no |
OLA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTBP2_HUMAN | [view interactions] | Low throughput | no | no |
LIMS1_HUMAN | [view interactions] | Low throughput | no | yes |
UBE2N_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNH2_HUMAN | [view interactions] | Low throughput | no | no |
DNJB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IL4RA_HUMAN | [view interactions] | Low throughput | no | no |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
CIP2A_HUMAN | [view interactions] | Low throughput | no | yes |
PA2G4_HUMAN | [view interactions] | Low throughput | no | yes |
PROF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
INO80_HUMAN | [view interactions] | Low throughput | no | no |
P63_HUMAN | [view interactions] | Low throughput | no | no |
TRIM6_HUMAN | [view interactions] | Low throughput | no | no |
NUCG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ESR2_HUMAN | [view interactions] | Low throughput | no | no |
M3K11_HUMAN | [view interactions] | Low throughput | no | yes |
FOXP3_HUMAN | [view interactions] | Low throughput | no | no |
ERN1_HUMAN | [view interactions] | Low throughput | no | yes |
RFOX3_HUMAN | [view interactions] | Low throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ROA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ATGA1_HUMAN | [view interactions] | Low throughput | no | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
MCF2_HUMAN | [view interactions] | Low throughput | no | no |
ABC3G_HUMAN | [view interactions] | Low throughput | no | no |
ANM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CP3A4_HUMAN | [view interactions] | Low throughput | no | no |
P53_HUMAN | [view interactions] | Low throughput | no | no |
XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
UB2V1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
UB2E2_HUMAN | [view interactions] | Low throughput | no | yes |
SP7_HUMAN | [view interactions] | Low throughput | no | no |
FBX27_HUMAN | [view interactions] | Low throughput | no | yes |
NLRP3_HUMAN | [view interactions] | Low throughput | no | yes |
SMAD2_HUMAN | [view interactions] | Low throughput | no | yes |
UBP19_HUMAN | [view interactions] | Low throughput | no | no |
UB2E1_HUMAN | [view interactions] | Low throughput | no | yes |
BACE1_HUMAN | [view interactions] | Low throughput | no | yes |
UB2E3_HUMAN | [view interactions] | Low throughput | no | yes |
CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBE2W_HUMAN | [view interactions] | Low throughput | no | yes |
AIFM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IF5A1_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
M3K21_HUMAN | [view interactions] | Low throughput | no | yes |
UFO_HUMAN | [view interactions] | Low throughput | no | no |
UB2D4_HUMAN | [view interactions] | Low throughput | no | yes |
KCNA5_HUMAN | [view interactions] | Low throughput | no | no |
CASP6_HUMAN | [view interactions] | Low throughput | no | no |
TITIN_HUMAN | [view interactions] | Low throughput | no | no |
HIPK2_HUMAN | [view interactions] | Low throughput | no | yes |
DPOLB_HUMAN | [view interactions] | Low throughput | no | yes |
PARP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLC1B_HUMAN | [view interactions] | Low throughput | no | no |
CP2E1_HUMAN | [view interactions] | Low throughput | no | no |
PPARG_HUMAN | [view interactions] | Low throughput | no | yes |
JOS1_HUMAN | [view interactions] | Low throughput | no | no |
JOS2_HUMAN | [view interactions] | Low throughput | no | no |
RFX1_HUMAN | [view interactions] | Low throughput | no | yes |
NOTC1_HUMAN | [view interactions] | Low throughput | no | yes |
ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP21_HUMAN | [view interactions] | Low throughput | no | no |
ADRM1_HUMAN | [view interactions] | Low throughput | no | yes |
PRS7_HUMAN | [view interactions] | Low throughput | no | yes |
UN45B_HUMAN | [view interactions] | Low throughput | no | no |
RHDF2_HUMAN | [view interactions] | Low throughput | no | yes |
SENP3_HUMAN | [view interactions] | Low throughput | no | yes |
2AAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CDN1A_HUMAN | [view interactions] | Low throughput | no | no |
BAG5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SC6A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AQP2_HUMAN | [view interactions] | Low throughput | no | no |
TPD52_HUMAN | [view interactions] | Low throughput | no | yes |
SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
UB2L3_HUMAN | [view interactions] | Low throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
M3K14_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
CFLAR_HUMAN | [view interactions] | Low throughput | no | yes |
EZH2_HUMAN | [view interactions] | Low throughput | no | no |
RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
STK11_HUMAN | [view interactions] | Low throughput | no | yes |
INSR_HUMAN | [view interactions] | Low throughput | no | yes |
TF_HUMAN | [view interactions] | Low throughput | no | no |
SIR6_HUMAN | [view interactions] | Low throughput | no | yes |
PABP2_HUMAN | [view interactions] | Low throughput | no | yes |
BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
PLK1_HUMAN | [view interactions] | Low throughput | no | yes |
HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
TFEB_HUMAN | [view interactions] | Low throughput | no | no |
PSMD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRP75_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KMT2E_HUMAN | [view interactions] | Low throughput | no | no |
UBA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DDX58_HUMAN | [view interactions] | Low throughput | no | yes |
UB2D2_HUMAN | [view interactions] | Low throughput | no | yes |
AL1L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PO5F1_HUMAN | [view interactions] | Low throughput | no | yes |
HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DNJB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RUNX2_HUMAN | [view interactions] | Low throughput | no | no |
SMAD1_HUMAN | [view interactions] | Low throughput | no | yes |
DAAF4_HUMAN | [view interactions] | Low throughput | no | yes |
ANDR_HUMAN | [view interactions] | Low throughput | no | no |
UBX2A_HUMAN | [view interactions] | Low throughput | no | no |
DDIAS_HUMAN | [view interactions] | Low throughput | no | no |
SNAI1_HUMAN | [view interactions] | Low throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GCYA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TAL1_HUMAN | [view interactions] | Low throughput | no | no |
M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
AHR_HUMAN | [view interactions] | Low throughput | no | yes |
ATX1_HUMAN | [view interactions] | Low throughput | no | yes |
RON_HUMAN | [view interactions] | Low throughput | no | yes |
TERA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SNPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IF4E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLAT_HUMAN | [view interactions] | Low throughput | no | yes |
AIMP2_HUMAN | [view interactions] | Low throughput | no | yes |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
IRS4_HUMAN | [view interactions] | Low throughput | no | no |
KC1G2_HUMAN | [view interactions] | Low throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FADD_HUMAN | [view interactions] | Low throughput | no | yes |
PARK7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SODC_HUMAN | [view interactions] | Low throughput | no | yes |
PAR10_HUMAN | [view interactions] | Low throughput | no | yes |
BMP7_HUMAN | [view interactions] | High throughput | no | no |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
DDX60_HUMAN | [view interactions] | High throughput | no | no |
TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
HPSE_HUMAN | [view interactions] | High throughput | no | no |
PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
TERF2_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRD8_HUMAN | [view interactions] | High throughput | no | yes |
CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
CIC_HUMAN | [view interactions] | High throughput | no | yes |
BRD4_HUMAN | [view interactions] | High throughput | no | yes |
CFAD_HUMAN | [view interactions] | High throughput | no | no |
TLR9_HUMAN | [view interactions] | High throughput | no | no |
FNDC5_HUMAN | [view interactions] | High throughput | no | no |
DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA4_HUMAN | [view interactions] | High throughput | no | yes |
DJB12_HUMAN | [view interactions] | High throughput | no | yes |
EPAS1_HUMAN | [view interactions] | High throughput | no | no |
DJB14_HUMAN | [view interactions] | High throughput | no | yes |
DNJB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB5_HUMAN | [view interactions] | High throughput | no | yes |
DNJB8_HUMAN | [view interactions] | High throughput | no | no |
DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DJC12_HUMAN | [view interactions] | High throughput | no | yes |
DJC16_HUMAN | [view interactions] | High throughput | no | no |
DJC18_HUMAN | [view interactions] | High throughput | no | yes |
DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJB11_HUMAN | [view interactions] | High throughput | no | yes |
KDF1_HUMAN | [view interactions] | High throughput | no | yes |
RIN3_HUMAN | [view interactions] | High throughput | no | yes |
MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
MARH4_HUMAN | [view interactions] | High throughput | no | yes |
PSB2_HUMAN | [view interactions] | High throughput | no | yes |
PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UFL1_HUMAN | [view interactions] | High throughput | no | yes |
PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ABCG2_HUMAN | [view interactions] | High throughput | no | no |
SKA3_HUMAN | [view interactions] | High throughput | no | no |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
URGCP_HUMAN | [view interactions] | High throughput | no | yes |
KHDC1_HUMAN | [view interactions] | High throughput | no | no |
PKHO1_HUMAN | [view interactions] | High throughput | no | no |
TLE2_HUMAN | [view interactions] | High throughput | no | yes |
HORM2_HUMAN | [view interactions] | High throughput | no | no |
ELP4_HUMAN | [view interactions] | High throughput | no | yes |
PLD2_HUMAN | [view interactions] | High throughput | no | yes |
MCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX10_HUMAN | [view interactions] | High throughput | no | no |
L2GL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRGR_HUMAN | [view interactions] | High throughput | no | no |
NOD2_HUMAN | [view interactions] | High throughput | no | yes |
TEAD3_HUMAN | [view interactions] | High throughput | no | no |
TEBP_HUMAN | [view interactions] | High throughput | no | yes |
PI3R6_HUMAN | [view interactions] | High throughput | no | yes |
K0100_HUMAN | [view interactions] | High throughput | no | yes |
PACRG_HUMAN | [view interactions] | High throughput | no | no |
AP5Z1_HUMAN | [view interactions] | High throughput | no | yes |
NANOG_HUMAN | [view interactions] | High throughput | no | no |
VP13B_HUMAN | [view interactions] | High throughput | no | no |
NANP8_HUMAN | [view interactions] | High throughput | no | no |
NOXO1_HUMAN | [view interactions] | High throughput | no | no |
CP2W1_HUMAN | [view interactions] | High throughput | no | no |
KLH33_HUMAN | [view interactions] | High throughput | no | yes |
FA12_HUMAN | [view interactions] | High throughput | no | no |
BAG4_HUMAN | [view interactions] | High throughput | no | yes |
PTN18_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
AL3B1_HUMAN | [view interactions] | High throughput | no | yes |
CD37L_HUMAN | [view interactions] | High throughput | no | yes |
KCNQ4_HUMAN | [view interactions] | High throughput | no | yes |
T185A_HUMAN | [view interactions] | High throughput | no | no |
NADE_HUMAN | [view interactions] | High throughput | no | yes |
PLPL5_HUMAN | [view interactions] | High throughput | no | no |
HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LOXL4_HUMAN | [view interactions] | High throughput | no | no |
MLF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADCY3_HUMAN | [view interactions] | High throughput | no | yes |
S12A3_HUMAN | [view interactions] | High throughput | no | no |
INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
VWA2_HUMAN | [view interactions] | High throughput | no | no |
HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DYR1B_HUMAN | [view interactions] | High throughput | no | no |
TRI68_HUMAN | [view interactions] | High throughput | no | yes |
TXLNG_HUMAN | [view interactions] | High throughput | no | no |
KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
SOLH1_HUMAN | [view interactions] | High throughput | no | no |
HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
KCNC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MK06_HUMAN | [view interactions] | High throughput | no | yes |
S61A1_HUMAN | [view interactions] | High throughput | no | no |
CC038_HUMAN | [view interactions] | High throughput | no | yes |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
NPAS1_HUMAN | [view interactions] | High throughput | no | no |
LST8_HUMAN | [view interactions] | High throughput | no | yes |
ARAF_HUMAN | [view interactions] | High throughput | no | yes |
ASB4_HUMAN | [view interactions] | High throughput | no | no |
ARC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
ASB10_HUMAN | [view interactions] | High throughput | no | no |
LEF1_HUMAN | [view interactions] | High throughput | no | no |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMR1A_HUMAN | [view interactions] | High throughput | no | no |
FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGO1_HUMAN | [view interactions] | High throughput | no | no |
NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
KLH29_HUMAN | [view interactions] | High throughput | no | yes |
TOM40_HUMAN | [view interactions] | High throughput | no | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
JAK3_HUMAN | [view interactions] | High throughput | no | no |
DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
CATL1_HUMAN | [view interactions] | High throughput | no | yes |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNAI2_HUMAN | [view interactions] | High throughput | no | yes |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
KSR2_HUMAN | [view interactions] | High throughput | no | yes |
PCSK9_HUMAN | [view interactions] | High throughput | no | no |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
MTA70_HUMAN | [view interactions] | High throughput | no | no |
NEK4_HUMAN | [view interactions] | High throughput | no | yes |
PELI3_HUMAN | [view interactions] | High throughput | no | yes |
CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJC17_HUMAN | [view interactions] | High throughput | no | yes |
L2GL2_HUMAN | [view interactions] | High throughput | no | yes |
FITM2_HUMAN | [view interactions] | High throughput | no | no |
HMGN3_HUMAN | [view interactions] | High throughput | no | yes |
KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
ACD_HUMAN | [view interactions] | High throughput | no | no |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPM_HUMAN | [view interactions] | High throughput | no | no |
TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOS_HUMAN | [view interactions] | High throughput | no | no |
KSR1_HUMAN | [view interactions] | High throughput | no | yes |
ERG_HUMAN | [view interactions] | High throughput | no | yes |
KAPCG_HUMAN | [view interactions] | High throughput | no | no |
UBX10_HUMAN | [view interactions] | High throughput | no | yes |
MK04_HUMAN | [view interactions] | High throughput | no | no |
ACHA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UB2V2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GRK6_HUMAN | [view interactions] | High throughput | no | yes |
OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
CLK3_HUMAN | [view interactions] | High throughput | no | yes |
CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K9_HUMAN | [view interactions] | High throughput | no | yes |
PDK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYLK_HUMAN | [view interactions] | High throughput | no | no |
PKDCC_HUMAN | [view interactions] | High throughput | no | no |
PKN3_HUMAN | [view interactions] | High throughput | no | yes |
WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
CDK4_HUMAN | [view interactions] | High throughput | no | no |
ADCK1_HUMAN | [view interactions] | High throughput | no | no |
PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEK8_HUMAN | [view interactions] | High throughput | no | yes |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
CDK20_HUMAN | [view interactions] | High throughput | no | yes |
FLCN_HUMAN | [view interactions] | High throughput | no | yes |
ANKK1_HUMAN | [view interactions] | High throughput | no | no |
KLH34_HUMAN | [view interactions] | High throughput | no | no |
MYO3B_HUMAN | [view interactions] | High throughput | no | yes |
S27A3_HUMAN | [view interactions] | High throughput | no | no |
KPSH2_HUMAN | [view interactions] | High throughput | no | no |
ABH15_HUMAN | [view interactions] | High throughput | no | yes |
E2AK1_HUMAN | [view interactions] | High throughput | no | yes |
TELT_HUMAN | [view interactions] | High throughput | no | no |
RD23B_HUMAN | [view interactions] | High throughput | no | yes |
TSSK1_HUMAN | [view interactions] | High throughput | no | no |
NAT16_HUMAN | [view interactions] | High throughput | no | no |
SRXN1_HUMAN | [view interactions] | High throughput | no | no |
STRAB_HUMAN | [view interactions] | High throughput | no | no |
P4HA2_HUMAN | [view interactions] | High throughput | no | no |
SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYRK4_HUMAN | [view interactions] | High throughput | no | no |
TYSD1_HUMAN | [view interactions] | High throughput | no | yes |
SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNRK_HUMAN | [view interactions] | High throughput | no | yes |
KCND2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ST1A1_HUMAN | [view interactions] | High throughput | no | no |
LATS2_HUMAN | [view interactions] | High throughput | no | yes |
KLDC2_HUMAN | [view interactions] | High throughput | no | yes |
NUBP2_HUMAN | [view interactions] | High throughput | no | yes |
AAKG3_HUMAN | [view interactions] | High throughput | no | no |
DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STAM1_HUMAN | [view interactions] | High throughput | no | yes |
SIK3_HUMAN | [view interactions] | High throughput | no | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
SC24A_HUMAN | [view interactions] | High throughput | no | no |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CD81_HUMAN | [view interactions] | High throughput | no | no |
TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MITF_HUMAN | [view interactions] | High throughput | no | no |
PRP19_HUMAN | [view interactions] | High throughput | no | yes |
NOE3_HUMAN | [view interactions] | High throughput | no | no |
RHG17_HUMAN | [view interactions] | High throughput | no | no |
UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
THIOM_HUMAN | [view interactions] | High throughput | no | yes |
BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RUSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDK6_HUMAN | [view interactions] | High throughput | no | yes |
CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCL28_HUMAN | [view interactions] | High throughput | no | yes |
FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
TRI14_HUMAN | [view interactions] | High throughput | no | yes |
E2F8_HUMAN | [view interactions] | High throughput | no | yes |
FOSL2_HUMAN | [view interactions] | High throughput | no | yes |
DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RGS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GCNT4_HUMAN | [view interactions] | High throughput | no | yes |
DC1I1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
A2MG_HUMAN | [view interactions] | High throughput | no | yes |
GPSM2_HUMAN | [view interactions] | High throughput | no | yes |
ENTR1_HUMAN | [view interactions] | High throughput | no | no |
AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LAMB2_HUMAN | [view interactions] | High throughput | no | yes |
TDRD3_HUMAN | [view interactions] | High throughput | no | yes |
GLE1_HUMAN | [view interactions] | High throughput | no | yes |
RM19_HUMAN | [view interactions] | High throughput | no | yes |
HAX1_HUMAN | [view interactions] | High throughput | no | no |
GRN_HUMAN | [view interactions] | High throughput | no | no |
OTX1_HUMAN | [view interactions] | High throughput | no | no |
MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PERM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MERL_HUMAN | [view interactions] | High throughput | no | yes |
ITF2_HUMAN | [view interactions] | High throughput | no | yes |
ANC2_HUMAN | [view interactions] | High throughput | no | no |
TNR16_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
COIL_HUMAN | [view interactions] | High throughput | no | yes |
ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VPS4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXAR_HUMAN | [view interactions] | High throughput | no | yes |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AAAS_HUMAN | [view interactions] | High throughput | no | yes |
DYR2_HUMAN | [view interactions] | High throughput | no | yes |
RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GALA_HUMAN | [view interactions] | High throughput | no | no |
RHG33_HUMAN | [view interactions] | High throughput | no | yes |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AT11C_HUMAN | [view interactions] | High throughput | no | no |
LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
CYH1_HUMAN | [view interactions] | High throughput | no | no |
BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CENPU_HUMAN | [view interactions] | High throughput | no | no |
NU155_HUMAN | [view interactions] | High throughput | no | yes |
FKBP6_HUMAN | [view interactions] | High throughput | no | no |
CNBP_HUMAN | [view interactions] | High throughput | no | no |
PEX14_HUMAN | [view interactions] | High throughput | no | yes |
DJC25_HUMAN | [view interactions] | High throughput | no | yes |
RPB3_HUMAN | [view interactions] | High throughput | no | yes |
RCN2_HUMAN | [view interactions] | High throughput | no | yes |
DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IF6_HUMAN | [view interactions] | High throughput | no | yes |
PXMP2_HUMAN | [view interactions] | High throughput | no | no |
NCAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F193A_HUMAN | [view interactions] | High throughput | no | yes |
BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
ACE2_HUMAN | [view interactions] | High throughput | no | no |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
HELB_HUMAN | [view interactions] | High throughput | no | no |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CISD2_HUMAN | [view interactions] | High throughput | no | yes |
HSDL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HACL2_HUMAN | [view interactions] | High throughput | no | yes |
KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
INT5_HUMAN | [view interactions] | High throughput | no | no |
EM55_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KIFC3_HUMAN | [view interactions] | High throughput | no | no |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIFC1_HUMAN | [view interactions] | High throughput | no | yes |
M3K3_HUMAN | [view interactions] | High throughput | no | no |
MSI2H_HUMAN | [view interactions] | High throughput | no | yes |
PRC2B_HUMAN | [view interactions] | High throughput | no | no |
RL26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHKG2_HUMAN | [view interactions] | High throughput | no | no |
RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPSF3_HUMAN | [view interactions] | High throughput | no | yes |
RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KDM4B_HUMAN | [view interactions] | High throughput | no | no |
RTF2_HUMAN | [view interactions] | High throughput | no | yes |
REC8_HUMAN | [view interactions] | High throughput | no | yes |
SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
SP110_HUMAN | [view interactions] | High throughput | no | no |
SP1_HUMAN | [view interactions] | High throughput | no | yes |
CI072_HUMAN | [view interactions] | High throughput | no | no |
TAF6_HUMAN | [view interactions] | High throughput | no | no |
LRRK1_HUMAN | [view interactions] | High throughput | no | yes |
TOPB1_HUMAN | [view interactions] | High throughput | no | yes |
MFHA1_HUMAN | [view interactions] | High throughput | no | yes |
UBP2L_HUMAN | [view interactions] | High throughput | no | yes |
TERF1_HUMAN | [view interactions] | High throughput | no | no |
VKOR1_HUMAN | [view interactions] | High throughput | no | yes |
POTE1_HUMAN | [view interactions] | High throughput | no | no |
DC2I2_HUMAN | [view interactions] | High throughput | no | yes |
WDR83_HUMAN | [view interactions] | High throughput | no | yes |
TET3_HUMAN | [view interactions] | High throughput | no | yes |
YIF1B_HUMAN | [view interactions] | High throughput | no | yes |
FBX24_HUMAN | [view interactions] | High throughput | no | no |
MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERCC3_HUMAN | [view interactions] | High throughput | no | yes |
TGFB1_HUMAN | [view interactions] | High throughput | no | no |
MCM5_HUMAN | [view interactions] | High throughput | no | no |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
CLCN2_HUMAN | [view interactions] | High throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NAL12_HUMAN | [view interactions] | High throughput | no | yes |
HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
SIM2_HUMAN | [view interactions] | High throughput | no | yes |
NPRL2_HUMAN | [view interactions] | High throughput | no | yes |
HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
KLH38_HUMAN | [view interactions] | High throughput | no | no |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
FX4L6_HUMAN | [view interactions] | High throughput | no | no |
RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
EIPR1_HUMAN | [view interactions] | High throughput | no | yes |
PRP8_HUMAN | [view interactions] | High throughput | no | yes |
TFDP3_HUMAN | [view interactions] | High throughput | no | no |
UBP49_HUMAN | [view interactions] | High throughput | no | yes |
HUS1B_HUMAN | [view interactions] | High throughput | no | no |
CTCFL_HUMAN | [view interactions] | High throughput | no | no |
SMRD2_HUMAN | [view interactions] | High throughput | no | no |
UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MLF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
HACD3_HUMAN | [view interactions] | High throughput | no | yes |
SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSF2_HUMAN | [view interactions] | High throughput | no | no |
HAVR1_HUMAN | [view interactions] | High throughput | no | yes |
DYN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WWOX_HUMAN | [view interactions] | High throughput | no | yes |
STIL_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
MOONR_HUMAN | [view interactions] | High throughput | no | yes |
LBN_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AL9A1_HUMAN | [view interactions] | High throughput | no | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAN2_HUMAN | [view interactions] | High throughput | no | no |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TINF2_HUMAN | [view interactions] | High throughput | no | no |
DX39B_HUMAN | [view interactions] | High throughput | no | no |
G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MPRI_HUMAN | [view interactions] | High throughput | no | yes |
TGFR1_HUMAN | [view interactions] | High throughput | no | no |
LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMR1B_HUMAN | [view interactions] | High throughput | no | no |
LEG1_HUMAN | [view interactions] | High throughput | no | yes |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPYM_HUMAN | [view interactions] | High throughput | no | yes |
GPR37_HUMAN | [view interactions] | High throughput | no | no |
PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STMN2_HUMAN | [view interactions] | High throughput | no | no |
VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT38_HUMAN | [view interactions] | High throughput | no | no |
CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FAF1_HUMAN | [view interactions] | High throughput | no | yes |
UBE2B_HUMAN | [view interactions] | Computational | no | no |
ERBIN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
UBE2A_HUMAN | [view interactions] | Computational | no | no |
RNF5_HUMAN | [view interactions] | Computational | no | yes |
UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RIPK1_HUMAN | [view interactions] | Computational | no | yes |
BTAF1_HUMAN | [view interactions] | Computational | no | no |
UBE4A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
HSPB8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |