BAIP2_HUMAN
Evidence for PS localization
Functions
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002442 | LIG_PDZ_Class_1 | LIG | 516 | 521 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in BAIP2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 34.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 33.0000 | 4 | no |
| GO:0019900 | kinase binding | 32.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 32.0000 | 4 | no |
| GO:0019901 | protein kinase binding | 26.0000 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 23.0000 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.0000 | 5 | no |
| GO:0005524 | ATP binding | 21.0000 | 5 | no |
| GO:0016301 | kinase activity | 21.0000 | 4 | no |
| GO:0045296 | cadherin binding | 16.0000 | 4 | yes |
| GO:0030165 | PDZ domain binding | 5.0000 | 4 | yes |
| GO:0001221 | transcription coregulator binding | 3.0000 | 4 | yes |
| GO:0098631 | cell adhesion mediator activity | 2.0000 | 4 | yes |
| GO:0098632 | cell-cell adhesion mediator activity | 2.0000 | 5 | yes |
| GO:0098641 | cadherin binding involved in cell-cell adhesion | 2.0000 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in BAIP2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 77.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 68.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 63.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 62.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 62.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 61.0000 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 60.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 60.0000 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 55.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 55.0000 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 50.0000 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 48.0000 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 47.0000 | 6 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 46.0000 | 5 | no |
| GO:0022607 | cellular component assembly | 45.0000 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 44.0000 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 44.0000 | 5 | no |
| GO:0030030 | cell projection organization | 42.0000 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 41.0000 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 41.0000 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 40.0000 | 6 | no |
| GO:0010468 | regulation of gene expression | 40.0000 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 39.0000 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 39.0000 | 5 | no |
| GO:0006996 | organelle organization | 39.0000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 39.0000 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 38.0000 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 37.0000 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 37.0000 | 6 | no |
| GO:0051049 | regulation of transport | 37.0000 | 4 | no |
| GO:0008104 | protein localization | 37.0000 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 37.0000 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 37.0000 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 36.0000 | 7 | no |
| GO:1902531 | regulation of intracellular signal transduction | 36.0000 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 35.0000 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 34.0000 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 33.0000 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 33.0000 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 32.0000 | 7 | no |
| GO:0043085 | positive regulation of catalytic activity | 32.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 32.0000 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 32.0000 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 32.0000 | 7 | yes |
| GO:0009889 | regulation of biosynthetic process | 31.0000 | 4 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 31.0000 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 31.0000 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 30.0000 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 30.0000 | 7 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 30.0000 | 5 | no |
| GO:0031346 | positive regulation of cell projection organization | 30.0000 | 6 | yes |
| GO:0051094 | positive regulation of developmental process | 29.0000 | 4 | yes |
| GO:0030334 | regulation of cell migration | 29.0000 | 5 | no |
| GO:2000145 | regulation of cell motility | 29.0000 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 29.0000 | 7 | no |
| GO:0042327 | positive regulation of phosphorylation | 29.0000 | 8 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.0000 | 5 | no |
| GO:0007010 | cytoskeleton organization | 29.0000 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 28.0000 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 28.0000 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 28.0000 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 28.0000 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 28.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.0000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.0000 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.0000 | 5 | no |
| GO:0036211 | protein modification process | 27.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 27.0000 | 4 | no |
| GO:0031175 | neuron projection development | 27.0000 | 6 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 27.0000 | 5 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 26.0000 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 26.0000 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 26.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.0000 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 26.0000 | 6 | yes |
| GO:0097435 | supramolecular fiber organization | 25.0000 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 25.0000 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 25.0000 | 8 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 25.0000 | 4 | yes |
| GO:0060284 | regulation of cell development | 24.0000 | 5 | yes |
| GO:0110053 | regulation of actin filament organization | 24.0000 | 6 | yes |
| GO:0043549 | regulation of kinase activity | 24.0000 | 5 | no |
| GO:0008284 | positive regulation of cell population proliferation | 24.0000 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 24.0000 | 4 | no |
| GO:0051960 | regulation of nervous system development | 23.0000 | 5 | yes |
| GO:0032880 | regulation of protein localization | 23.0000 | 5 | no |
| GO:0051347 | positive regulation of transferase activity | 23.0000 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 23.0000 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.0000 | 4 | no |
| GO:0080134 | regulation of response to stress | 23.0000 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.0000 | 4 | no |
| GO:0034330 | cell junction organization | 23.0000 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 23.0000 | 5 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 22.0000 | 7 | yes |
| GO:0051129 | negative regulation of cellular component organization | 22.0000 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.0000 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.0000 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.0000 | 6 | no |
| GO:0010941 | regulation of cell death | 22.0000 | 4 | no |
| GO:0043269 | regulation of ion transport | 22.0000 | 5 | no |
| GO:0007015 | actin filament organization | 22.0000 | 5 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 22.0000 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 21.0000 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 21.0000 | 6 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 21.0000 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 21.0000 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 21.0000 | 6 | no |
| GO:0051336 | regulation of hydrolase activity | 21.0000 | 4 | no |
| GO:0030335 | positive regulation of cell migration | 21.0000 | 6 | no |
| GO:0040017 | positive regulation of locomotion | 21.0000 | 4 | no |
| GO:0043408 | regulation of MAPK cascade | 21.0000 | 6 | no |
| GO:2000147 | positive regulation of cell motility | 21.0000 | 5 | no |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 21.0000 | 5 | yes |
| GO:0032990 | cell part morphogenesis | 21.0000 | 4 | yes |
| GO:0048858 | cell projection morphogenesis | 21.0000 | 5 | yes |
| GO:1901699 | cellular response to nitrogen compound | 20.0000 | 4 | yes |
| GO:0022604 | regulation of cell morphogenesis | 20.0000 | 5 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 19.0000 | 4 | yes |
| GO:0048812 | neuron projection morphogenesis | 19.0000 | 7 | yes |
| GO:0050767 | regulation of neurogenesis | 19.0000 | 6 | yes |
| GO:0010720 | positive regulation of cell development | 18.0000 | 6 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 18.0000 | 5 | yes |
| GO:0050808 | synapse organization | 17.0000 | 5 | yes |
| GO:0070848 | response to growth factor | 17.0000 | 4 | yes |
| GO:0044057 | regulation of system process | 16.0000 | 4 | yes |
| GO:0051962 | positive regulation of nervous system development | 15.0000 | 5 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 15.0000 | 5 | yes |
| GO:0032271 | regulation of protein polymerization | 15.0000 | 6 | yes |
| GO:0050769 | positive regulation of neurogenesis | 14.0000 | 6 | yes |
| GO:0061024 | membrane organization | 14.0000 | 4 | yes |
| GO:0010976 | positive regulation of neuron projection development | 14.0000 | 7 | yes |
| GO:0008360 | regulation of cell shape | 13.0000 | 6 | yes |
| GO:0032535 | regulation of cellular component size | 13.0000 | 4 | yes |
| GO:0050773 | regulation of dendrite development | 12.0000 | 4 | yes |
| GO:0099175 | regulation of postsynapse organization | 12.0000 | 6 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 12.0000 | 6 | yes |
| GO:0008064 | regulation of actin polymerization or depolymerization | 11.0000 | 6 | yes |
| GO:0030832 | regulation of actin filament length | 11.0000 | 5 | yes |
| GO:0030833 | regulation of actin filament polymerization | 11.0000 | 7 | yes |
| GO:0032273 | positive regulation of protein polymerization | 11.0000 | 7 | yes |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 10.0000 | 6 | yes |
| GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 10.0000 | 7 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 9.0000 | 5 | yes |
| GO:0007409 | axonogenesis | 9.0000 | 8 | yes |
| GO:0031644 | regulation of nervous system process | 9.0000 | 5 | yes |
| GO:0048814 | regulation of dendrite morphogenesis | 9.0000 | 5 | yes |
| GO:0060998 | regulation of dendritic spine development | 8.0000 | 4 | yes |
| GO:2000249 | regulation of actin cytoskeleton reorganization | 8.0000 | 6 | yes |
| GO:0030838 | positive regulation of actin filament polymerization | 8.0000 | 7 | yes |
| GO:0060999 | positive regulation of dendritic spine development | 7.0000 | 5 | yes |
| GO:0099563 | modification of synaptic structure | 7.0000 | 6 | yes |
| GO:1902414 | protein localization to cell junction | 7.0000 | 5 | yes |
| GO:1905244 | regulation of modification of synaptic structure | 7.0000 | 6 | yes |
| GO:2000251 | positive regulation of actin cytoskeleton reorganization | 7.0000 | 7 | yes |
| GO:0098815 | modulation of excitatory postsynaptic potential | 6.0000 | 4 | yes |
| GO:2000463 | positive regulation of excitatory postsynaptic potential | 6.0000 | 5 | yes |
| GO:0050775 | positive regulation of dendrite morphogenesis | 5.0000 | 6 | yes |
| GO:0071364 | cellular response to epidermal growth factor stimulus | 5.0000 | 4 | yes |
| GO:0099159 | regulation of modification of postsynaptic structure | 5.0000 | 7 | yes |
| GO:0007420 | brain development | 5.0000 | 4 | yes |
| GO:0035418 | protein localization to synapse | 5.0000 | 6 | yes |
| GO:0051017 | actin filament bundle assembly | 4.0000 | 5 | yes |
| GO:0061003 | positive regulation of dendritic spine morphogenesis | 4.0000 | 6 | yes |
| GO:0061572 | actin filament bundle organization | 4.0000 | 6 | yes |
| GO:1905274 | regulation of modification of postsynaptic actin cytoskeleton | 4.0000 | 8 | yes |
| GO:0008286 | insulin receptor signaling pathway | 4.0000 | 6 | yes |
| GO:0043200 | response to amino acid | 4.0000 | 4 | yes |
| GO:0051764 | actin crosslink formation | 3.0000 | 6 | yes |
| GO:0007009 | plasma membrane organization | 3.0000 | 5 | yes |
| GO:0071229 | cellular response to acid chemical | 2.0000 | 4 | yes |
| GO:0071230 | cellular response to amino acid stimulus | 2.0000 | 5 | yes |
| GO:0099564 | modification of synaptic structure, modulating synaptic transmission | 2.0000 | 7 | yes |
| GO:1902065 | response to L-glutamate | 2.0000 | 5 | yes |
| GO:1905232 | cellular response to L-glutamate | 2.0000 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in BAIP2_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.0000 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MARK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATN1_HUMAN | [view interactions] | Low throughput | no | yes |
| LIN7B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI1_HUMAN | [view interactions] | Low throughput | no | no |
| ABI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDZD2_HUMAN | [view interactions] | Low throughput | no | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DIAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KANK1_HUMAN | [view interactions] | Low throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ESPN_HUMAN | [view interactions] | Low throughput | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CNKR3_HUMAN | [view interactions] | Low throughput | no | yes |
| SHAN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| INADL_HUMAN | [view interactions] | Low throughput | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GID4_HUMAN | [view interactions] | High throughput | no | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| SRRT_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |
| ES8L1_HUMAN | [view interactions] | High throughput | no | no |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
| VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CF132_HUMAN | [view interactions] | High throughput | no | no |
| PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL3_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8A_HUMAN | [view interactions] | High throughput | no | no |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
| TPC11_HUMAN | [view interactions] | High throughput | no | no |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VASP_HUMAN | [view interactions] | High throughput | no | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| PBX2_HUMAN | [view interactions] | High throughput | no | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIL2_HUMAN | [view interactions] | High throughput | no | yes |
| CHMP6_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFIP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFB1M_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DECR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H15_HUMAN | [view interactions] | High throughput | no | no |
| NRDC_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRR13_HUMAN | [view interactions] | High throughput | no | yes |
| CS025_HUMAN | [view interactions] | High throughput | no | no |
| SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
| ERG28_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDM2_HUMAN | [view interactions] | High throughput | no | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROR1_HUMAN | [view interactions] | High throughput | no | no |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI13B_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT21_HUMAN | [view interactions] | High throughput | no | yes |
| RAB3I_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBX5_HUMAN | [view interactions] | High throughput | no | no |
| SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXD8_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1522_HUMAN | [view interactions] | High throughput | no | yes |
| MPZL1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM26_HUMAN | [view interactions] | High throughput | no | yes |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHRF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ABI3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| WASF3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TIAM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DIAP3_HUMAN | [view interactions] | Computational | no | no |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| WASP_HUMAN | [view interactions] | Computational | no | yes |