HECW2_HUMAN
Evidence for PS localization
Functions
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 1191 | Arg | Gln | Neurodevelopmentaldisorderwithhypotonia,seizures,andabsentlanguage(NDHSAL) | - |
| 1193 | Phe | Val | Neurodevelopmentaldisorderwithhypotonia,seizures,andabsentlanguage(NDHSAL) | - |
| 1330 | Arg | Trp | Neurodevelopmentaldisorderwithhypotonia,seizures,andabsentlanguage(NDHSAL) | - |
| 1445 | Glu | Gly | Neurodevelopmentaldisorderwithhypotonia,seizures,andabsentlanguage(NDHSAL) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in HECW2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 22.8070 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.8070 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.8070 | 4 | no |
| GO:0004842 | ubiquitin-protein transferase activity | 7.0175 | 4 | yes |
| GO:0061630 | ubiquitin protein ligase activity | 7.0175 | 5 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 7.0175 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HECW2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 49.1228 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.6140 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 45.6140 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 40.3509 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 40.3509 | 4 | yes |
| GO:0010646 | regulation of cell communication | 38.5965 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.8421 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 36.8421 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 35.0877 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 33.3333 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.5789 | 5 | yes |
| GO:0006996 | organelle organization | 29.8246 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.0702 | 5 | yes |
| GO:0036211 | protein modification process | 26.3158 | 4 | yes |
| GO:0043412 | macromolecule modification | 26.3158 | 4 | yes |
| GO:0051049 | regulation of transport | 26.3158 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 26.3158 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.3158 | 5 | no |
| GO:0033043 | regulation of organelle organization | 24.5614 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 24.5614 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 22.8070 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 22.8070 | 4 | no |
| GO:0010468 | regulation of gene expression | 22.8070 | 5 | no |
| GO:0008104 | protein localization | 22.8070 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.0526 | 6 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 21.0526 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 21.0526 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 21.0526 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 19.2982 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 19.2982 | 5 | yes |
| GO:0051726 | regulation of cell cycle | 19.2982 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 19.2982 | 6 | yes |
| GO:0010564 | regulation of cell cycle process | 17.5439 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 17.5439 | 7 | yes |
| GO:0051051 | negative regulation of transport | 17.5439 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 15.7895 | 4 | yes |
| GO:0034762 | regulation of transmembrane transport | 14.0351 | 4 | yes |
| GO:0043269 | regulation of ion transport | 14.0351 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 12.2807 | 5 | yes |
| GO:0034763 | negative regulation of transmembrane transport | 12.2807 | 5 | yes |
| GO:0034765 | regulation of ion transmembrane transport | 12.2807 | 5 | yes |
| GO:0043271 | negative regulation of ion transport | 12.2807 | 5 | yes |
| GO:0050773 | regulation of dendrite development | 12.2807 | 4 | yes |
| GO:0006508 | proteolysis | 10.5263 | 4 | yes |
| GO:0010959 | regulation of metal ion transport | 10.5263 | 6 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 10.5263 | 4 | yes |
| GO:0032410 | negative regulation of transporter activity | 10.5263 | 4 | yes |
| GO:0032412 | regulation of ion transmembrane transporter activity | 10.5263 | 5 | yes |
| GO:0032413 | negative regulation of ion transmembrane transporter activity | 10.5263 | 5 | yes |
| GO:0034766 | negative regulation of ion transmembrane transport | 10.5263 | 6 | yes |
| GO:0042176 | regulation of protein catabolic process | 10.5263 | 5 | yes |
| GO:1904062 | regulation of cation transmembrane transport | 10.5263 | 6 | yes |
| GO:1904063 | negative regulation of cation transmembrane transport | 10.5263 | 7 | yes |
| GO:0009057 | macromolecule catabolic process | 8.7719 | 4 | yes |
| GO:0016567 | protein ubiquitination | 8.7719 | 7 | yes |
| GO:0032446 | protein modification by small protein conjugation | 8.7719 | 6 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 8.7719 | 4 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 8.7719 | 6 | yes |
| GO:0048814 | regulation of dendrite morphogenesis | 8.7719 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 8.7719 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 8.7719 | 5 | yes |
| GO:0000209 | protein polyubiquitination | 7.0175 | 8 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 7.0175 | 7 | yes |
| GO:0007346 | regulation of mitotic cell cycle | 7.0175 | 5 | yes |
| GO:0010498 | proteasomal protein catabolic process | 7.0175 | 5 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 7.0175 | 6 | yes |
| GO:0030163 | protein catabolic process | 7.0175 | 4 | yes |
| GO:0033044 | regulation of chromosome organization | 7.0175 | 6 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.0175 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 7.0175 | 5 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 7.0175 | 4 | yes |
| GO:0002028 | regulation of sodium ion transport | 5.2632 | 7 | yes |
| GO:0010766 | negative regulation of sodium ion transport | 5.2632 | 6 | yes |
| GO:0051983 | regulation of chromosome segregation | 5.2632 | 4 | yes |
| GO:1901987 | regulation of cell cycle phase transition | 5.2632 | 6 | yes |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 5.2632 | 6 | yes |
| GO:1902305 | regulation of sodium ion transmembrane transport | 5.2632 | 7 | yes |
| GO:1902306 | negative regulation of sodium ion transmembrane transport | 5.2632 | 7 | yes |
| GO:1905818 | regulation of chromosome separation | 5.2632 | 5 | yes |
| GO:2000649 | regulation of sodium ion transmembrane transporter activity | 5.2632 | 6 | yes |
| GO:2000650 | negative regulation of sodium ion transmembrane transporter activity | 5.2632 | 6 | yes |
| GO:0010965 | regulation of mitotic sister chromatid separation | 3.5088 | 6 | yes |
| GO:0030071 | regulation of mitotic metaphase/anaphase transition | 3.5088 | 7 | yes |
| GO:0033045 | regulation of sister chromatid segregation | 3.5088 | 5 | yes |
| GO:1902099 | regulation of metaphase/anaphase transition of cell cycle | 3.5088 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in HECW2_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 5.2632 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 5.2632 | 5 | no |
| DOID:114 | heart disease | 5.2632 | 3 | no |
| DOID:2843 | long QT syndrome | 3.5088 | 6 | no |
| DOID:65 | connective tissue disease | 3.5088 | 3 | no |
| DOID:0050776 | non-syndromic X-linked intellectual disability | 3.5088 | 6 | no |
| DOID:0050889 | non-syndromic intellectual disability | 3.5088 | 5 | no |
| DOID:0060038 | specific developmental disorder | 3.5088 | 3 | no |
| DOID:1059 | intellectual disability | 3.5088 | 4 | no |
| DOID:331 | central nervous system disease | 3.5088 | 3 | no |
| DOID:936 | brain disease | 3.5088 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LMNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBX3_HUMAN | [view interactions] | Low throughput | no | yes |
| P73_HUMAN | [view interactions] | Low throughput | no | no |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| FZR1_HUMAN | [view interactions] | Low throughput | no | no |
| AMOT_HUMAN | [view interactions] | Low throughput | no | no |
| AMOL2_HUMAN | [view interactions] | Low throughput | no | no |
| CBX1_HUMAN | [view interactions] | Low throughput | no | yes |
| CBX5_HUMAN | [view interactions] | Low throughput | no | yes |
| PCNA_HUMAN | [view interactions] | Low throughput | no | no |
| LMNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AMOL1_HUMAN | [view interactions] | Low throughput | no | no |
| UB2D3_HUMAN | [view interactions] | Low throughput | no | yes |
| UB2L3_HUMAN | [view interactions] | Low throughput | no | yes |
| RCL1_HUMAN | [view interactions] | High throughput | no | no |
| SO4C1_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEIOB_HUMAN | [view interactions] | High throughput | no | no |
| F133B_HUMAN | [view interactions] | High throughput | no | no |
| MA7D1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MORC2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALKB5_HUMAN | [view interactions] | High throughput | no | yes |
| ASTE1_HUMAN | [view interactions] | High throughput | no | no |
| SRPK1_HUMAN | [view interactions] | High throughput | no | yes |
| S35E1_HUMAN | [view interactions] | High throughput | no | yes |
| RU2B_HUMAN | [view interactions] | High throughput | no | yes |
| APC4_HUMAN | [view interactions] | High throughput | no | yes |
| CABIN_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RING1_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LACRT_HUMAN | [view interactions] | High throughput | no | no |
| CHTOP_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCAP_HUMAN | [view interactions] | High throughput | no | yes |
| KMT2A_HUMAN | [view interactions] | High throughput | no | yes |
| SPNDC_HUMAN | [view interactions] | High throughput | no | yes |
| GPAM1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMB1_HUMAN | [view interactions] | High throughput | no | yes |
| LAR4B_HUMAN | [view interactions] | High throughput | no | yes |
| MED16_HUMAN | [view interactions] | High throughput | no | yes |
| MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PXDN_HUMAN | [view interactions] | High throughput | no | no |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| PKCB1_HUMAN | [view interactions] | High throughput | no | yes |
| PYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| TAAR2_HUMAN | [view interactions] | High throughput | no | no |
| U3IP2_HUMAN | [view interactions] | High throughput | no | yes |
| VP33B_HUMAN | [view interactions] | High throughput | no | yes |
| ZMAT4_HUMAN | [view interactions] | High throughput | no | yes |
| ZN207_HUMAN | [view interactions] | High throughput | no | yes |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| MORC4_HUMAN | [view interactions] | High throughput | no | no |
| MAZ_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
| TRM2A_HUMAN | [view interactions] | High throughput | no | yes |
| ACL6A_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC1_HUMAN | [view interactions] | High throughput | no | yes |
| CATIN_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS7_HUMAN | [view interactions] | High throughput | no | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NO40_HUMAN | [view interactions] | High throughput | no | yes |
| PHC2_HUMAN | [view interactions] | High throughput | no | yes |
| FRG1_HUMAN | [view interactions] | High throughput | no | yes |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| APC5_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDC16_HUMAN | [view interactions] | High throughput | no | yes |
| CDYL_HUMAN | [view interactions] | High throughput | no | yes |
| F120A_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BGAT_HUMAN | [view interactions] | High throughput | no | no |
| MED12_HUMAN | [view interactions] | High throughput | no | yes |
| MCES_HUMAN | [view interactions] | High throughput | no | yes |
| NELFA_HUMAN | [view interactions] | High throughput | no | yes |
| NOSIP_HUMAN | [view interactions] | High throughput | no | yes |
| PWP2_HUMAN | [view interactions] | High throughput | no | no |
| PHF6_HUMAN | [view interactions] | High throughput | no | yes |
| PI51A_HUMAN | [view interactions] | High throughput | no | yes |
| DHX36_HUMAN | [view interactions] | High throughput | no | yes |
| LS14A_HUMAN | [view interactions] | High throughput | no | yes |
| POP1_HUMAN | [view interactions] | High throughput | no | no |
| MRM3_HUMAN | [view interactions] | High throughput | no | yes |
| SRS10_HUMAN | [view interactions] | High throughput | no | yes |
| CHK1_HUMAN | [view interactions] | High throughput | no | no |
| PKN2_HUMAN | [view interactions] | High throughput | no | yes |
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| SPHK2_HUMAN | [view interactions] | High throughput | no | no |
| SMHD1_HUMAN | [view interactions] | High throughput | no | yes |
| TAF5L_HUMAN | [view interactions] | High throughput | no | no |
| WDR36_HUMAN | [view interactions] | High throughput | no | yes |
| WBP11_HUMAN | [view interactions] | High throughput | no | yes |
| ZN638_HUMAN | [view interactions] | High throughput | no | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| XRN1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP5_HUMAN | [view interactions] | High throughput | no | yes |
| ASCC3_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AFF4_HUMAN | [view interactions] | High throughput | no | yes |
| APC1_HUMAN | [view interactions] | High throughput | no | no |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD6_HUMAN | [view interactions] | High throughput | no | yes |
| CAR14_HUMAN | [view interactions] | High throughput | no | no |
| CNO10_HUMAN | [view interactions] | High throughput | no | yes |
| CENPF_HUMAN | [view interactions] | High throughput | no | no |
| CEP55_HUMAN | [view interactions] | High throughput | no | yes |
| KGP1_HUMAN | [view interactions] | High throughput | no | yes |
| HUS1_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTF3_HUMAN | [view interactions] | High throughput | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCRU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRTC2_HUMAN | [view interactions] | High throughput | no | yes |
| CCNA1_HUMAN | [view interactions] | High throughput | no | no |
| CCNK_HUMAN | [view interactions] | High throughput | no | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCNL5_HUMAN | [view interactions] | High throughput | no | yes |
| DRS7B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSBP_HUMAN | [view interactions] | High throughput | no | yes |
| KIN17_HUMAN | [view interactions] | High throughput | no | no |
| RPB2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYSF_HUMAN | [view interactions] | High throughput | no | no |
| EP400_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTH_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3J_HUMAN | [view interactions] | High throughput | no | yes |
| ECM1_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP20H_HUMAN | [view interactions] | High throughput | no | yes |
| SHCAF_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG7_HUMAN | [view interactions] | High throughput | no | no |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| GATD1_HUMAN | [view interactions] | High throughput | no | no |
| GLCI1_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENR1_HUMAN | [view interactions] | High throughput | no | yes |
| HM20A_HUMAN | [view interactions] | High throughput | no | yes |
| KAT2A_HUMAN | [view interactions] | High throughput | no | no |
| ANR65_HUMAN | [view interactions] | High throughput | no | no |
| HROB_HUMAN | [view interactions] | High throughput | no | yes |
| INT4_HUMAN | [view interactions] | High throughput | no | yes |
| E2AK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMC1_HUMAN | [view interactions] | High throughput | no | yes |
| AVL9_HUMAN | [view interactions] | High throughput | no | yes |
| LMBL3_HUMAN | [view interactions] | High throughput | no | yes |
| ACSL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLUR2_HUMAN | [view interactions] | High throughput | no | no |
| LYNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GMPPA_HUMAN | [view interactions] | High throughput | no | no |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| MAP11_HUMAN | [view interactions] | High throughput | no | yes |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| MILK1_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1S_HUMAN | [view interactions] | High throughput | no | no |
| TOM34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAD5_HUMAN | [view interactions] | High throughput | no | no |
| MOB1A_HUMAN | [view interactions] | High throughput | no | yes |
| ESCO1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR5_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP5_HUMAN | [view interactions] | High throughput | no | no |
| NCOA5_HUMAN | [view interactions] | High throughput | no | yes |
| SEH1_HUMAN | [view interactions] | High throughput | no | no |
| NTPCR_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC1_HUMAN | [view interactions] | High throughput | no | no |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PX11B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PM34_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHF3_HUMAN | [view interactions] | High throughput | no | yes |
| EGFLA_HUMAN | [view interactions] | High throughput | no | no |
| PA1B2_HUMAN | [view interactions] | High throughput | no | yes |
| KAT8_HUMAN | [view interactions] | High throughput | no | no |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| PSB3_HUMAN | [view interactions] | High throughput | no | yes |
| PSB7_HUMAN | [view interactions] | High throughput | no | yes |
| ANGE2_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LS14B_HUMAN | [view interactions] | High throughput | no | yes |
| PB1_HUMAN | [view interactions] | High throughput | no | yes |
| S10AE_HUMAN | [view interactions] | High throughput | no | no |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| MOS_HUMAN | [view interactions] | High throughput | no | no |
| F1892_HUMAN | [view interactions] | High throughput | no | yes |
| PNPH_HUMAN | [view interactions] | High throughput | no | no |
| FXL15_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| LITAF_HUMAN | [view interactions] | High throughput | no | yes |
| RB15B_HUMAN | [view interactions] | High throughput | no | yes |
| TMM51_HUMAN | [view interactions] | High throughput | no | yes |
| RSPH9_HUMAN | [view interactions] | High throughput | no | no |
| ARRD3_HUMAN | [view interactions] | High throughput | no | no |
| RADIL_HUMAN | [view interactions] | High throughput | no | no |
| WBP1_HUMAN | [view interactions] | High throughput | no | yes |
| REN3B_HUMAN | [view interactions] | High throughput | no | yes |
| ARRD1_HUMAN | [view interactions] | High throughput | no | yes |
| RTL9_HUMAN | [view interactions] | High throughput | no | no |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| RNAS4_HUMAN | [view interactions] | High throughput | no | no |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A4_HUMAN | [view interactions] | High throughput | no | yes |
| ELOA2_HUMAN | [view interactions] | High throughput | no | yes |
| CTR9_HUMAN | [view interactions] | High throughput | no | yes |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| HECW1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCAPE_HUMAN | [view interactions] | High throughput | no | yes |
| RAI1_HUMAN | [view interactions] | High throughput | no | yes |
| SRBD1_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCML2_HUMAN | [view interactions] | High throughput | no | no |
| INCE_HUMAN | [view interactions] | High throughput | no | no |
| SPAST_HUMAN | [view interactions] | High throughput | no | yes |
| DIDO1_HUMAN | [view interactions] | High throughput | no | yes |
| TALD3_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| AP2A_HUMAN | [view interactions] | High throughput | no | no |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| SP2_HUMAN | [view interactions] | High throughput | no | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAD2B_HUMAN | [view interactions] | High throughput | no | yes |
| GGCT_HUMAN | [view interactions] | High throughput | no | yes |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| DUS3L_HUMAN | [view interactions] | High throughput | no | yes |
| KDM4D_HUMAN | [view interactions] | High throughput | no | yes |
| TSC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEP1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| F120B_HUMAN | [view interactions] | High throughput | no | yes |
| UBP21_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| MIO_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YETS4_HUMAN | [view interactions] | High throughput | no | no |
| RAD54_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB9_HUMAN | [view interactions] | High throughput | no | no |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3H3_HUMAN | [view interactions] | High throughput | no | yes |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| Z3H7B_HUMAN | [view interactions] | High throughput | no | no |
| YTHD3_HUMAN | [view interactions] | High throughput | no | no |
| ZN579_HUMAN | [view interactions] | High throughput | no | yes |
| CDT1_HUMAN | [view interactions] | High throughput | no | yes |
| ZF64B_HUMAN | [view interactions] | High throughput | no | no |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAB3_HUMAN | [view interactions] | High throughput | no | no |
| CBX4_HUMAN | [view interactions] | High throughput | no | yes |
| ZSWM6_HUMAN | [view interactions] | High throughput | no | no |
| ENAH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZP3_HUMAN | [view interactions] | High throughput | no | no |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| F189B_HUMAN | [view interactions] | High throughput | no | no |
| ZZZ3_HUMAN | [view interactions] | High throughput | no | yes |
| LRAD4_HUMAN | [view interactions] | High throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN14_HUMAN | [view interactions] | High throughput | no | yes |
| NSE4A_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRIM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAMD1_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| DMAP1_HUMAN | [view interactions] | High throughput | no | yes |
| NPL4_HUMAN | [view interactions] | High throughput | no | yes |
| RPOM_HUMAN | [view interactions] | High throughput | no | yes |
| XIRP2_HUMAN | [view interactions] | High throughput | no | no |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| TM174_HUMAN | [view interactions] | High throughput | no | no |
| RBM28_HUMAN | [view interactions] | High throughput | no | yes |
| TMED7_HUMAN | [view interactions] | High throughput | no | yes |
| SPB12_HUMAN | [view interactions] | High throughput | no | no |
| M4A10_HUMAN | [view interactions] | High throughput | no | no |
| CHAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LRP3_HUMAN | [view interactions] | High throughput | no | no |
| DOPD_HUMAN | [view interactions] | High throughput | no | yes |
| TMG1_HUMAN | [view interactions] | High throughput | no | no |
| ERCC6_HUMAN | [view interactions] | High throughput | no | no |
| IDD_HUMAN | [view interactions] | High throughput | no | no |
| TIRR_HUMAN | [view interactions] | High throughput | no | no |
| CUED1_HUMAN | [view interactions] | High throughput | no | yes |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| ILDR1_HUMAN | [view interactions] | High throughput | no | no |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| WIZ_HUMAN | [view interactions] | High throughput | no | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDC20_HUMAN | [view interactions] | High throughput | no | no |
| APT_HUMAN | [view interactions] | High throughput | no | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBIP1_HUMAN | [view interactions] | High throughput | no | yes |