GIPC1_HUMAN
Evidence for PS localization
Functions
May be involved in G protein-linked signaling. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GIPC1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 24.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.0000 | 4 | no |
| GO:0019900 | kinase binding | 22.0000 | 4 | no |
| GO:0046872 | metal ion binding | 22.0000 | 4 | no |
| GO:0003779 | actin binding | 18.0000 | 4 | yes |
| GO:0045296 | cadherin binding | 12.0000 | 4 | yes |
| GO:0017022 | myosin binding | 4.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GIPC1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 58.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 58.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 52.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 48.0000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 46.0000 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 46.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 42.0000 | 4 | yes |
| GO:0008104 | protein localization | 40.0000 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 40.0000 | 4 | yes |
| GO:0051049 | regulation of transport | 36.0000 | 4 | yes |
| GO:0071702 | organic substance transport | 36.0000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 36.0000 | 5 | no |
| GO:0030334 | regulation of cell migration | 34.0000 | 5 | no |
| GO:2000145 | regulation of cell motility | 34.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.0000 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 30.0000 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.0000 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 30.0000 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 30.0000 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.0000 | 5 | no |
| GO:0022607 | cellular component assembly | 30.0000 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 30.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 30.0000 | 5 | no |
| GO:0010941 | regulation of cell death | 30.0000 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.0000 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 28.0000 | 5 | yes |
| GO:0015031 | protein transport | 28.0000 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 28.0000 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 28.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 28.0000 | 5 | yes |
| GO:0051726 | regulation of cell cycle | 28.0000 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 28.0000 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 28.0000 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 28.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.0000 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 26.0000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.0000 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.0000 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 24.0000 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 24.0000 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 24.0000 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0000 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 24.0000 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.0000 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 24.0000 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.0000 | 5 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 24.0000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.0000 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 24.0000 | 6 | no |
| GO:0006886 | intracellular protein transport | 22.0000 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 22.0000 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 22.0000 | 6 | no |
| GO:0016192 | vesicle-mediated transport | 22.0000 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.0000 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.0000 | 6 | no |
| GO:0051050 | positive regulation of transport | 22.0000 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 22.0000 | 4 | no |
| GO:0006996 | organelle organization | 22.0000 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.0000 | 6 | no |
| GO:0051493 | regulation of cytoskeleton organization | 22.0000 | 6 | no |
| GO:0010564 | regulation of cell cycle process | 20.0000 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.0000 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 18.0000 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 18.0000 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 18.0000 | 6 | yes |
| GO:0051046 | regulation of secretion | 18.0000 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 16.0000 | 6 | yes |
| GO:1903530 | regulation of secretion by cell | 16.0000 | 4 | yes |
| GO:0042176 | regulation of protein catabolic process | 14.0000 | 5 | yes |
| GO:0099537 | trans-synaptic signaling | 14.0000 | 4 | yes |
| GO:0001667 | ameboidal-type cell migration | 12.0000 | 4 | yes |
| GO:0006811 | ion transport | 12.0000 | 4 | yes |
| GO:0007268 | chemical synaptic transmission | 12.0000 | 6 | yes |
| GO:0015849 | organic acid transport | 12.0000 | 5 | yes |
| GO:0017157 | regulation of exocytosis | 12.0000 | 5 | yes |
| GO:0031329 | regulation of cellular catabolic process | 12.0000 | 5 | yes |
| GO:0034097 | response to cytokine | 12.0000 | 4 | yes |
| GO:0046903 | secretion | 12.0000 | 4 | yes |
| GO:0051588 | regulation of neurotransmitter transport | 12.0000 | 5 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 12.0000 | 5 | yes |
| GO:1903305 | regulation of regulated secretory pathway | 12.0000 | 6 | yes |
| GO:0006820 | anion transport | 10.0000 | 5 | yes |
| GO:0015711 | organic anion transport | 10.0000 | 5 | yes |
| GO:0030162 | regulation of proteolysis | 10.0000 | 6 | yes |
| GO:0045787 | positive regulation of cell cycle | 10.0000 | 5 | yes |
| GO:0046928 | regulation of neurotransmitter secretion | 10.0000 | 4 | yes |
| GO:0046942 | carboxylic acid transport | 10.0000 | 6 | yes |
| GO:0071345 | cellular response to cytokine stimulus | 10.0000 | 5 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 10.0000 | 4 | yes |
| GO:2000300 | regulation of synaptic vesicle exocytosis | 10.0000 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 8.0000 | 5 | yes |
| GO:0031330 | negative regulation of cellular catabolic process | 8.0000 | 6 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 8.0000 | 7 | yes |
| GO:0032465 | regulation of cytokinesis | 8.0000 | 5 | yes |
| GO:0032467 | positive regulation of cytokinesis | 8.0000 | 6 | yes |
| GO:0045861 | negative regulation of proteolysis | 8.0000 | 7 | yes |
| GO:0051302 | regulation of cell division | 8.0000 | 4 | yes |
| GO:0051781 | positive regulation of cell division | 8.0000 | 5 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 8.0000 | 6 | yes |
| GO:0090068 | positive regulation of cell cycle process | 8.0000 | 6 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 8.0000 | 7 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 8.0000 | 6 | yes |
| GO:0006605 | protein targeting | 6.0000 | 5 | yes |
| GO:0006835 | dicarboxylic acid transport | 6.0000 | 7 | yes |
| GO:0006865 | amino acid transport | 6.0000 | 5 | yes |
| GO:0010631 | epithelial cell migration | 6.0000 | 5 | yes |
| GO:0014047 | glutamate secretion | 6.0000 | 4 | yes |
| GO:0015800 | acidic amino acid transport | 6.0000 | 6 | yes |
| GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 6.0000 | 8 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 6.0000 | 6 | yes |
| GO:0043455 | regulation of secondary metabolic process | 6.0000 | 4 | yes |
| GO:0043542 | endothelial cell migration | 6.0000 | 6 | yes |
| GO:0048021 | regulation of melanin biosynthetic process | 6.0000 | 6 | yes |
| GO:0048023 | positive regulation of melanin biosynthetic process | 6.0000 | 7 | yes |
| GO:0090092 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 6.0000 | 5 | yes |
| GO:1900376 | regulation of secondary metabolite biosynthetic process | 6.0000 | 5 | yes |
| GO:1900378 | positive regulation of secondary metabolite biosynthetic process | 6.0000 | 6 | yes |
| GO:1901799 | negative regulation of proteasomal protein catabolic process | 6.0000 | 7 | yes |
| GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | 6.0000 | 8 | yes |
| GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 6.0000 | 7 | yes |
| GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway | 4.0000 | 6 | yes |
| GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway | 4.0000 | 6 | yes |
| GO:0090100 | positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 4.0000 | 6 | yes |
| GO:0098760 | response to interleukin-7 | 4.0000 | 5 | yes |
| GO:0098761 | cellular response to interleukin-7 | 4.0000 | 6 | yes |
| GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus | 4.0000 | 5 | yes |
| GO:1903846 | positive regulation of cellular response to transforming growth factor beta stimulus | 4.0000 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in GIPC1_HUMAN |
|---|---|---|---|---|
| DOID:37 | skin disease | 4.0000 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PKHG5_HUMAN | [view interactions] | Low throughput | no | yes |
| MYO6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARHGC_HUMAN | [view interactions] | Low throughput | no | yes |
| TGBR3_HUMAN | [view interactions] | Low throughput | no | yes |
| BCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TYRP1_HUMAN | [view interactions] | Low throughput | no | no |
| SH3B4_HUMAN | [view interactions] | Low throughput | no | yes |
| SCN7A_HUMAN | [view interactions] | Low throughput | no | no |
| LSHR_HUMAN | [view interactions] | Low throughput | no | no |
| DRD3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ITA6_HUMAN | [view interactions] | Low throughput | no | yes |
| ITA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| C1QR1_HUMAN | [view interactions] | Low throughput | no | no |
| CAR10_HUMAN | [view interactions] | Low throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | Low throughput | no | yes |
| LPAR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LPAR2_HUMAN | [view interactions] | Low throughput | no | yes |
| PLXD1_HUMAN | [view interactions] | Low throughput | no | yes |
| ADRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRP2_HUMAN | [view interactions] | Low throughput | no | no |
| NTRK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TPBG_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS19_HUMAN | [view interactions] | Low throughput | no | yes |
| GTR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYH6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KIF1B_HUMAN | [view interactions] | Low throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SEM4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDIT3_HUMAN | [view interactions] | High throughput | no | yes |
| PKHG6_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
| SSRD_HUMAN | [view interactions] | High throughput | no | yes |
| PDXD1_HUMAN | [view interactions] | High throughput | no | no |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
| NUP93_HUMAN | [view interactions] | High throughput | no | yes |
| SYMC_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA2_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| LRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRP8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RNF41_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIPC2_HUMAN | [view interactions] | High throughput | no | yes |
| DP13B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIPC3_HUMAN | [view interactions] | High throughput | no | no |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGME1_HUMAN | [view interactions] | High throughput | no | yes |
| KLH13_HUMAN | [view interactions] | High throughput | no | no |
| KLHL9_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| GGA1_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCL_HUMAN | [view interactions] | High throughput | no | yes |
| BID_HUMAN | [view interactions] | High throughput | no | no |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAMP3_HUMAN | [view interactions] | High throughput | no | no |
| CELF1_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| GULP1_HUMAN | [view interactions] | High throughput | no | no |
| SI1L3_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| STRN3_HUMAN | [view interactions] | High throughput | no | yes |
| FMNL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOCN_HUMAN | [view interactions] | High throughput | no | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRMD6_HUMAN | [view interactions] | High throughput | no | no |
| TOM1_HUMAN | [view interactions] | High throughput | no | yes |
| FBP1L_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN408_HUMAN | [view interactions] | High throughput | no | no |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYLT1_HUMAN | [view interactions] | Computational | no | no |
| DRD2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GDIR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VGFR2_HUMAN | [view interactions] | Computational | no | no |
| NGF_HUMAN | [view interactions] | Computational | no | no |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DYN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |