Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

COPB2_HUMAN

This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner . [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in COPB2_HUMAN
GO:0017076 purine nucleotide binding 27.9070 4 no
GO:0032555 purine ribonucleotide binding 27.9070 4 no
GO:0035639 purine ribonucleoside triphosphate binding 27.9070 4 no
GO:0003723 RNA binding 23.2558 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in COPB2_HUMAN
GO:0008104 protein localization 47.6744 4 yes
GO:0048522 positive regulation of cellular process 46.5116 4 no
GO:0071702 organic substance transport 44.1860 4 yes
GO:0031323 regulation of cellular metabolic process 43.0233 4 no
GO:0060255 regulation of macromolecule metabolic process 41.8605 4 no
GO:0080090 regulation of primary metabolic process 41.8605 4 no
GO:0071705 nitrogen compound transport 40.6977 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 40.6977 4 no
GO:0048523 negative regulation of cellular process 38.3721 4 no
GO:0015031 protein transport 36.0465 4 yes
GO:0010646 regulation of cell communication 36.0465 4 no
GO:0006996 organelle organization 33.7209 4 no
GO:0009893 positive regulation of metabolic process 32.5581 4 no
GO:0051128 regulation of cellular component organization 32.5581 4 no
GO:0009966 regulation of signal transduction 31.3953 4 no
GO:0006886 intracellular protein transport 30.2326 4 yes
GO:0010468 regulation of gene expression 27.9070 5 no
GO:0010604 positive regulation of macromolecule metabolic process 27.9070 5 no
GO:0051246 regulation of protein metabolic process 26.7442 5 no
GO:0016192 vesicle-mediated transport 25.5814 4 yes
GO:0009889 regulation of biosynthetic process 25.5814 4 no
GO:0009892 negative regulation of metabolic process 25.5814 4 no
GO:0031326 regulation of cellular biosynthetic process 25.5814 5 no
GO:0031325 positive regulation of cellular metabolic process 24.4186 5 no
GO:0023056 positive regulation of signaling 23.2558 4 no
GO:0033043 regulation of organelle organization 23.2558 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 23.2558 5 no
GO:0010556 regulation of macromolecule biosynthetic process 22.0930 5 no
GO:0010647 positive regulation of cell communication 22.0930 5 no
GO:0031324 negative regulation of cellular metabolic process 22.0930 5 no
GO:1902531 regulation of intracellular signal transduction 22.0930 5 no
GO:0010605 negative regulation of macromolecule metabolic process 20.9302 5 no
GO:0043412 macromolecule modification 20.9302 4 no
GO:0048193 Golgi vesicle transport 16.2791 5 yes
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 12.7907 4 yes
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 10.4651 6 yes
GO:0006891 intra-Golgi vesicle-mediated transport 4.6512 6 yes
GO:1901998 toxin transport 3.4884 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in COPB2_HUMAN
DOID:1289 neurodegenerative disease 2.3256 4 no
DOID:331 central nervous system disease 2.3256 3 no
DOID:0070281 primary autosomal recessive microcephaly 19 2.3256 6 yes
DOID:0070296 primary autosomal recessive microcephaly 2.3256 5 yes
DOID:0070297 primary microcephaly 2.3256 4 yes
DOID:10907 microcephaly 2.3256 3 yes
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RGS4_HUMAN [view interactions] Low throughput no no
COPE_HUMAN [view interactions] Low throughput no yes
COPB_HUMAN [view interactions] Low throughput no yes
MSRA_HUMAN [view interactions] Low throughput no no
KPCE_HUMAN [view entry] [view interactions] Low throughput yes yes
COPB2_HUMAN [view entry] [view interactions] Low throughput yes yes
COPD_HUMAN [view entry] [view interactions] Low throughput yes yes
COPZ1_HUMAN [view interactions] Low throughput no no
SCYL1_HUMAN [view interactions] Low throughput no yes
COPA_HUMAN [view entry] [view interactions] Low throughput yes yes
COPG1_HUMAN [view interactions] Low throughput no yes
GORAB_HUMAN [view interactions] Low throughput no yes
RGS2_HUMAN [view interactions] Low throughput no no
GIPC1_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
RTCA_HUMAN [view interactions] High throughput no yes
TOM70_HUMAN [view interactions] High throughput no yes
CDK4_HUMAN [view interactions] High throughput no no
HYOU1_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
CIAO1_HUMAN [view interactions] High throughput no yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
GSTK1_HUMAN [view entry] [view interactions] High throughput yes yes
PDIA6_HUMAN [view entry] [view interactions] High throughput yes yes
NDRG1_HUMAN [view entry] [view interactions] High throughput yes yes
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
SNW1_HUMAN [view interactions] High throughput no yes
RL27_HUMAN [view entry] [view interactions] High throughput yes yes
CDC5L_HUMAN [view interactions] High throughput no yes
SC23A_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
ZW10_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
NBAS_HUMAN [view interactions] High throughput no yes
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
RINT1_HUMAN [view interactions] High throughput no yes
CXAR_HUMAN [view interactions] High throughput no yes
MFHA1_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
CNTRL_HUMAN [view interactions] High throughput no yes
ELOV5_HUMAN [view interactions] High throughput no yes
CETN2_HUMAN [view interactions] High throughput no yes
MET7A_HUMAN [view interactions] High throughput no no
CEP19_HUMAN [view interactions] High throughput no no
SSRA_HUMAN [view entry] [view interactions] High throughput yes yes
TM237_HUMAN [view interactions] High throughput no no
STX4_HUMAN [view entry] [view interactions] High throughput yes no
NECD_HUMAN [view interactions] High throughput no no
STX6_HUMAN [view interactions] High throughput no yes
STAT3_HUMAN [view entry] [view interactions] High throughput yes yes
ZFPL1_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA7_HUMAN [view entry] [view interactions] High throughput yes no
EPHA8_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
VGFR3_HUMAN [view interactions] High throughput no yes
INSR_HUMAN [view interactions] High throughput no yes
MUSK_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
STYK1_HUMAN [view interactions] High throughput no yes
MCPH1_HUMAN [view interactions] High throughput no yes
NELFD_HUMAN [view interactions] High throughput no yes
DDA1_HUMAN [view interactions] High throughput no yes
HDAC5_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
COPG2_HUMAN [view interactions] High throughput no yes
LMAN1_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
FOXP3_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
STB5L_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
KCJ10_HUMAN [view interactions] High throughput no no
UNK_HUMAN [view interactions] High throughput no yes
RN126_HUMAN [view interactions] High throughput no yes
F210A_HUMAN [view interactions] High throughput no yes
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
RAD18_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
EDEM3_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
CDK9_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TPTE_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
RNF31_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
GLP1R_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
PKHA2_HUMAN [view interactions] High throughput no no
TGFR2_HUMAN [view interactions] High throughput no no
TM41B_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
S15A3_HUMAN [view interactions] High throughput no yes
MPIP1_HUMAN [view interactions] High throughput no no
MATR3_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
ARGAL_HUMAN [view interactions] High throughput no yes
DEP1B_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
INSI2_HUMAN [view interactions] High throughput no yes
FA20C_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
APR_HUMAN [view interactions] High throughput no yes
ISG15_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
ZBTB2_HUMAN [view interactions] High throughput no yes
COPZ2_HUMAN [view interactions] High throughput no no
SEC62_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
AGO2_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
SURF4_HUMAN [view interactions] High throughput no yes
RALY_HUMAN [view interactions] High throughput no yes
DHRS3_HUMAN [view interactions] High throughput no yes
RER1_HUMAN [view interactions] High throughput no yes
RAB18_HUMAN [view entry] [view interactions] High throughput yes yes
CGT_HUMAN [view interactions] High throughput no no
NSDHL_HUMAN [view interactions] High throughput no yes
TBCC_HUMAN [view interactions] High throughput no yes
VAS1_HUMAN [view interactions] High throughput no yes
DHB12_HUMAN [view entry] [view interactions] High throughput yes yes
SUGP2_HUMAN [view interactions] High throughput no yes
DHB11_HUMAN [view interactions] High throughput no yes
CISD2_HUMAN [view interactions] High throughput no yes
LCLT1_HUMAN [view interactions] High throughput no no
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
REEP5_HUMAN [view entry] [view interactions] High throughput yes yes
ARF5_HUMAN [view entry] [view interactions] High throughput yes no
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
SIM11_HUMAN [view interactions] High throughput no no
LBR_HUMAN [view interactions] High throughput no yes
SEPT2_HUMAN [view interactions] High throughput no no
RB3GP_HUMAN [view entry] [view interactions] High throughput yes yes
NONO_HUMAN [view interactions] High throughput no yes
RCN1_HUMAN [view interactions] High throughput no yes
ILF3_HUMAN [view interactions] High throughput no yes
PRDX4_HUMAN [view interactions] High throughput no yes
SUN2_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
APMAP_HUMAN [view interactions] High throughput no yes
AGO3_HUMAN [view interactions] High throughput no yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
TMX2_HUMAN [view interactions] High throughput no yes
DHRS7_HUMAN [view interactions] High throughput no yes
TMED5_HUMAN [view interactions] High throughput no yes
TX264_HUMAN [view interactions] High throughput no no
ASTRA_HUMAN [view interactions] High throughput no no
ERGI1_HUMAN [view interactions] High throughput no yes
CCD47_HUMAN [view interactions] High throughput no yes
RM24_HUMAN [view interactions] High throughput no yes
CLMN_HUMAN [view entry] [view interactions] High throughput yes no
RDH11_HUMAN [view interactions] High throughput no no
ATLA2_HUMAN [view entry] [view interactions] High throughput yes yes
ATLA1_HUMAN [view entry] [view interactions] High throughput yes yes
SCFD1_HUMAN [view entry] [view interactions] High throughput yes yes
RBGPR_HUMAN [view entry] [view interactions] High throughput yes yes
CPVL_HUMAN [view interactions] High throughput no no
NDC1_HUMAN [view interactions] High throughput no yes
ERP44_HUMAN [view interactions] High throughput no yes
ESYT1_HUMAN [view entry] [view interactions] High throughput yes yes
OSBL8_HUMAN [view interactions] High throughput no yes
ATLA3_HUMAN [view interactions] High throughput no no
SEPT7_HUMAN [view entry] [view interactions] High throughput yes yes
SEP11_HUMAN [view entry] [view interactions] High throughput yes yes
PSD3_HUMAN [view entry] [view interactions] High throughput yes yes
REEP4_HUMAN [view interactions] High throughput no no
LRCH3_HUMAN [view interactions] High throughput no yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
ZDHC3_HUMAN [view interactions] High throughput no yes
LST8_HUMAN [view interactions] High throughput no yes
AR6P1_HUMAN [view interactions] High throughput no yes
SEPT5_HUMAN [view interactions] High throughput no no
CC115_HUMAN [view interactions] High throughput no no
TMM33_HUMAN [view entry] [view interactions] High throughput yes yes
PTBP1_HUMAN [view interactions] High throughput no no
CBAR1_HUMAN [view interactions] High throughput no no
CP51A_HUMAN [view interactions] High throughput no no
MICA2_HUMAN [view interactions] High throughput no yes
MYEF2_HUMAN [view interactions] High throughput no no
ZN326_HUMAN [view interactions] High throughput no yes
DHC24_HUMAN [view interactions] High throughput no yes
VIP2_HUMAN [view interactions] High throughput no yes
EPT1_HUMAN [view interactions] High throughput no yes
MCM8_HUMAN [view interactions] High throughput no no
ESYT2_HUMAN [view entry] [view interactions] High throughput yes yes
SLMAP_HUMAN [view entry] [view interactions] High throughput yes yes
ITCH_HUMAN [view interactions] High throughput no yes
DSRAD_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC6_HUMAN [view entry] [view interactions] High throughput yes yes
HACL2_HUMAN [view interactions] High throughput no yes
SEPT3_HUMAN [view interactions] High throughput no no
SEPT6_HUMAN [view interactions] High throughput no yes
PRAF2_HUMAN [view entry] [view interactions] High throughput yes yes
SEPT8_HUMAN [view interactions] High throughput no no
INAR1_HUMAN [view interactions] High throughput no yes
ARF4_HUMAN [view entry] [view interactions] High throughput yes no
NFKB1_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
UBA5_HUMAN [view interactions] High throughput no yes
ITA6_HUMAN [view interactions] High throughput no yes
NUDC1_HUMAN [view interactions] High throughput no no
LKHA4_HUMAN [view interactions] High throughput no yes
HNRPC_HUMAN [view interactions] High throughput no yes
SAC1_HUMAN [view entry] [view interactions] High throughput yes yes
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
ATPD_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
UVRAG_HUMAN [view interactions] High throughput no yes
SERPH_HUMAN [view interactions] High throughput no no
HERC2_HUMAN [view interactions] High throughput no yes
AL7A1_HUMAN [view entry] [view interactions] High throughput yes no
PRD16_HUMAN [view interactions] High throughput no no
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
MECOM_HUMAN [view interactions] High throughput no yes
EI24_HUMAN [view interactions] High throughput no yes
PAK4_HUMAN [view interactions] High throughput no yes
HNRDL_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
GDPD1_HUMAN [view interactions] High throughput no no
RIN3_HUMAN [view interactions] High throughput no yes
RTN2_HUMAN [view interactions] High throughput no no
MOT11_HUMAN [view interactions] High throughput no no
KDSR_HUMAN [view interactions] High throughput no yes
PPM1G_HUMAN [view interactions] High throughput no no
ACSL3_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
PTBP3_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA2_HUMAN [view interactions] High throughput no yes
ENDD1_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
RTN3_HUMAN [view entry] [view interactions] High throughput yes yes
KDM1A_HUMAN [view interactions] High throughput no yes
CYB5_HUMAN [view interactions] High throughput no no
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
RENR_HUMAN [view entry] [view interactions] High throughput yes yes
TGON2_HUMAN [view interactions] High throughput no yes
STAM2_HUMAN [view interactions] High throughput no yes
HG2A_HUMAN [view interactions] High throughput no yes
ERLN1_HUMAN [view entry] [view interactions] High throughput yes yes
P2RY6_HUMAN [view interactions] High throughput no no
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
UN93B_HUMAN [view interactions] High throughput no yes
NOLC1_HUMAN [view interactions] High throughput no yes
PACE1_HUMAN [view interactions] High throughput no yes
OST4_HUMAN [view interactions] High throughput no no
KS6B2_HUMAN [view interactions] High throughput no yes
SPTC1_HUMAN [view interactions] High throughput no yes
SIK3_HUMAN [view interactions] High throughput no yes
ATG3_HUMAN [view interactions] High throughput no yes
SG196_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
TMEDA_HUMAN [view interactions] High throughput no yes
RIT1_HUMAN [view interactions] High throughput no yes
TMED9_HUMAN [view interactions] High throughput no yes
WBP2_HUMAN [view interactions] High throughput no yes
ROS1_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view interactions] High throughput no yes
BRF2_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CRCM_HUMAN [view interactions] High throughput no no
KLC4_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
RUFY1_HUMAN [view interactions] High throughput no yes
T22D1_HUMAN [view interactions] High throughput no no
TELO2_HUMAN [view interactions] High throughput no yes
TR10D_HUMAN [view interactions] High throughput no no
TTI1_HUMAN [view interactions] High throughput no yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
CIP4_HUMAN [view interactions] High throughput no no
MAGA6_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
SC23B_HUMAN [view interactions] Computational no yes
SYEP_HUMAN [view interactions] Computational no yes
STX18_HUMAN [view interactions] Computational no yes
ARFG3_HUMAN [view entry] [view interactions] Computational yes no
GOGB1_HUMAN [view entry] [view interactions] Computational yes yes
DIK2A_HUMAN [view interactions] Computational no yes
TMED7_HUMAN [view interactions] Computational no yes
ARF1_HUMAN [view entry] [view interactions] Computational yes yes
ARF3_HUMAN [view entry] [view interactions] Computational yes no
ERD21_HUMAN [view interactions] Computational no yes
ARFG2_HUMAN [view entry] [view interactions] Computational yes yes
BET1_HUMAN [view interactions] Computational no no
ARFG1_HUMAN [view interactions] Computational no no
USO1_HUMAN [view entry] [view interactions] Computational yes yes
SEC13_HUMAN [view entry] [view interactions] Computational yes yes