RTN4_HUMAN
Evidence for PS localization
Functions
Regulates cardiomyocyte apoptosis upon hypoxic conditions . With isoform B, inhibits BACE1 activity and amyloid precursor protein processing (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RTN4_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 29.3333 | 4 | no |
| GO:0000166 | nucleotide binding | 28.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 27.3333 | 5 | no |
| GO:0043169 | cation binding | 26.6667 | 4 | yes |
| GO:0046872 | metal ion binding | 25.3333 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 24.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.0000 | 4 | no |
| GO:0003723 | RNA binding | 16.6667 | 4 | yes |
| GO:0045296 | cadherin binding | 16.0000 | 4 | yes |
| GO:0042803 | protein homodimerization activity | 10.0000 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 9.3333 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 9.3333 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RTN4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 44.6667 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 43.3333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 42.6667 | 4 | yes |
| GO:0008104 | protein localization | 40.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 39.3333 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 38.6667 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 38.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 38.0000 | 4 | yes |
| GO:0006996 | organelle organization | 34.6667 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.6667 | 5 | yes |
| GO:0022607 | cellular component assembly | 34.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 32.6667 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 32.0000 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 32.0000 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 31.3333 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 30.6667 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.0000 | 5 | yes |
| GO:0071702 | organic substance transport | 29.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 29.3333 | 6 | yes |
| GO:0009892 | negative regulation of metabolic process | 28.0000 | 4 | yes |
| GO:0051049 | regulation of transport | 27.3333 | 4 | no |
| GO:0071705 | nitrogen compound transport | 26.6667 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.0000 | 4 | yes |
| GO:0043067 | regulation of programmed cell death | 25.3333 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 24.6667 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 24.0000 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 24.0000 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 24.0000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.0000 | 6 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.3333 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 23.3333 | 4 | yes |
| GO:0015031 | protein transport | 22.6667 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.6667 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.6667 | 5 | yes |
| GO:0030030 | cell projection organization | 22.0000 | 4 | yes |
| GO:0043933 | protein-containing complex organization | 22.0000 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 21.3333 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.3333 | 6 | yes |
| GO:0032880 | regulation of protein localization | 21.3333 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 21.3333 | 6 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.6667 | 6 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 20.6667 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 20.6667 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.6667 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 19.3333 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 18.0000 | 4 | yes |
| GO:0080134 | regulation of response to stress | 18.0000 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 16.6667 | 5 | yes |
| GO:0061024 | membrane organization | 16.6667 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 16.6667 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 16.6667 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 16.0000 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 16.0000 | 4 | yes |
| GO:0060284 | regulation of cell development | 16.0000 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 15.3333 | 6 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 15.3333 | 6 | yes |
| GO:0010628 | positive regulation of gene expression | 14.6667 | 7 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 14.6667 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 14.6667 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 14.0000 | 4 | yes |
| GO:0030334 | regulation of cell migration | 14.0000 | 5 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 14.0000 | 6 | yes |
| GO:2000145 | regulation of cell motility | 14.0000 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 13.3333 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 12.6667 | 4 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 12.6667 | 5 | yes |
| GO:0031175 | neuron projection development | 12.6667 | 6 | yes |
| GO:0032101 | regulation of response to external stimulus | 12.6667 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 12.0000 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 11.3333 | 7 | yes |
| GO:0001817 | regulation of cytokine production | 10.6667 | 4 | yes |
| GO:0050776 | regulation of immune response | 10.6667 | 4 | yes |
| GO:0006915 | apoptotic process | 10.0000 | 4 | yes |
| GO:0033365 | protein localization to organelle | 10.0000 | 5 | yes |
| GO:0051960 | regulation of nervous system development | 10.0000 | 5 | yes |
| GO:0001558 | regulation of cell growth | 9.3333 | 4 | yes |
| GO:0001819 | positive regulation of cytokine production | 9.3333 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 9.3333 | 6 | yes |
| GO:0031347 | regulation of defense response | 9.3333 | 5 | yes |
| GO:0040017 | positive regulation of locomotion | 9.3333 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 9.3333 | 6 | yes |
| GO:0050778 | positive regulation of immune response | 9.3333 | 5 | yes |
| GO:2000147 | positive regulation of cell motility | 9.3333 | 5 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 8.6667 | 4 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 8.6667 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 8.6667 | 4 | yes |
| GO:0045088 | regulation of innate immune response | 8.0000 | 5 | yes |
| GO:0030182 | neuron differentiation | 7.3333 | 4 | yes |
| GO:0031349 | positive regulation of defense response | 7.3333 | 5 | yes |
| GO:0048638 | regulation of developmental growth | 7.3333 | 4 | yes |
| GO:0002833 | positive regulation of response to biotic stimulus | 6.6667 | 5 | yes |
| GO:0007029 | endoplasmic reticulum organization | 6.6667 | 5 | yes |
| GO:0010721 | negative regulation of cell development | 6.6667 | 6 | yes |
| GO:0045089 | positive regulation of innate immune response | 6.6667 | 6 | yes |
| GO:0045596 | negative regulation of cell differentiation | 6.6667 | 5 | yes |
| GO:0036293 | response to decreased oxygen levels | 6.0000 | 4 | yes |
| GO:0050821 | protein stabilization | 6.0000 | 4 | yes |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 6.0000 | 6 | yes |
| GO:0002697 | regulation of immune effector process | 5.3333 | 4 | yes |
| GO:0002699 | positive regulation of immune effector process | 5.3333 | 5 | yes |
| GO:0010632 | regulation of epithelial cell migration | 5.3333 | 4 | yes |
| GO:0050678 | regulation of epithelial cell proliferation | 5.3333 | 5 | yes |
| GO:0071786 | endoplasmic reticulum tubular network organization | 5.3333 | 6 | yes |
| GO:1901342 | regulation of vasculature development | 5.3333 | 5 | yes |
| GO:0030308 | negative regulation of cell growth | 4.6667 | 5 | yes |
| GO:0030516 | regulation of axon extension | 4.6667 | 5 | yes |
| GO:0031345 | negative regulation of cell projection organization | 4.6667 | 6 | yes |
| GO:0045765 | regulation of angiogenesis | 4.6667 | 5 | yes |
| GO:0045926 | negative regulation of growth | 4.6667 | 4 | yes |
| GO:0050768 | negative regulation of neurogenesis | 4.6667 | 6 | yes |
| GO:0051961 | negative regulation of nervous system development | 4.6667 | 5 | yes |
| GO:0061387 | regulation of extent of cell growth | 4.6667 | 5 | yes |
| GO:0062207 | regulation of pattern recognition receptor signaling pathway | 4.6667 | 5 | yes |
| GO:0002685 | regulation of leukocyte migration | 4.0000 | 4 | yes |
| GO:0002687 | positive regulation of leukocyte migration | 4.0000 | 5 | yes |
| GO:0002700 | regulation of production of molecular mediator of immune response | 4.0000 | 5 | yes |
| GO:0002702 | positive regulation of production of molecular mediator of immune response | 4.0000 | 6 | yes |
| GO:0007420 | brain development | 4.0000 | 4 | yes |
| GO:0010634 | positive regulation of epithelial cell migration | 4.0000 | 5 | yes |
| GO:0010977 | negative regulation of neuron projection development | 4.0000 | 7 | yes |
| GO:0036294 | cellular response to decreased oxygen levels | 4.0000 | 5 | yes |
| GO:0039531 | regulation of cytoplasmic pattern recognition receptor signaling pathway | 4.0000 | 6 | yes |
| GO:0050679 | positive regulation of epithelial cell proliferation | 4.0000 | 6 | yes |
| GO:0050770 | regulation of axonogenesis | 4.0000 | 5 | yes |
| GO:0051057 | positive regulation of small GTPase mediated signal transduction | 4.0000 | 7 | yes |
| GO:0051896 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 4.0000 | 6 | yes |
| GO:0062208 | positive regulation of pattern recognition receptor signaling pathway | 4.0000 | 6 | yes |
| GO:0071453 | cellular response to oxygen levels | 4.0000 | 4 | yes |
| GO:0071456 | cellular response to hypoxia | 4.0000 | 4 | yes |
| GO:0090158 | endoplasmic reticulum membrane organization | 4.0000 | 5 | yes |
| GO:0002718 | regulation of cytokine production involved in immune response | 3.3333 | 5 | yes |
| GO:0002720 | positive regulation of cytokine production involved in immune response | 3.3333 | 6 | yes |
| GO:0034248 | regulation of amide metabolic process | 3.3333 | 4 | yes |
| GO:0045766 | positive regulation of angiogenesis | 3.3333 | 6 | yes |
| GO:0050771 | negative regulation of axonogenesis | 3.3333 | 6 | yes |
| GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 3.3333 | 7 | yes |
| GO:0071675 | regulation of mononuclear cell migration | 3.3333 | 5 | yes |
| GO:0071677 | positive regulation of mononuclear cell migration | 3.3333 | 6 | yes |
| GO:1904018 | positive regulation of vasculature development | 3.3333 | 5 | yes |
| GO:0021885 | forebrain cell migration | 2.6667 | 4 | yes |
| GO:0022029 | telencephalon cell migration | 2.6667 | 5 | yes |
| GO:0030517 | negative regulation of axon extension | 2.6667 | 6 | yes |
| GO:0034249 | negative regulation of amide metabolic process | 2.6667 | 5 | yes |
| GO:0048640 | negative regulation of developmental growth | 2.6667 | 5 | yes |
| GO:0060688 | regulation of morphogenesis of a branching structure | 2.6667 | 4 | yes |
| GO:0071787 | endoplasmic reticulum tubular network formation | 2.6667 | 5 | yes |
| GO:1902003 | regulation of amyloid-beta formation | 2.6667 | 5 | yes |
| GO:1902430 | negative regulation of amyloid-beta formation | 2.6667 | 6 | yes |
| GO:1902991 | regulation of amyloid precursor protein catabolic process | 2.6667 | 6 | yes |
| GO:1902992 | negative regulation of amyloid precursor protein catabolic process | 2.6667 | 7 | yes |
| GO:1990809 | endoplasmic reticulum tubular network membrane organization | 2.6667 | 6 | yes |
| GO:0001570 | vasculogenesis | 2.0000 | 4 | yes |
| GO:0001837 | epithelial to mesenchymal transition | 2.0000 | 5 | yes |
| GO:0006997 | nucleus organization | 2.0000 | 5 | yes |
| GO:0021795 | cerebral cortex cell migration | 2.0000 | 6 | yes |
| GO:0022009 | central nervous system vasculogenesis | 2.0000 | 5 | yes |
| GO:0035020 | regulation of Rac protein signal transduction | 2.0000 | 7 | yes |
| GO:0046931 | pore complex assembly | 2.0000 | 6 | yes |
| GO:0048762 | mesenchymal cell differentiation | 2.0000 | 4 | yes |
| GO:0061462 | protein localization to lysosome | 2.0000 | 7 | yes |
| GO:0072665 | protein localization to vacuole | 2.0000 | 6 | yes |
| GO:1901184 | regulation of ERBB signaling pathway | 2.0000 | 5 | yes |
| GO:0006999 | nuclear pore organization | 1.3333 | 5 | yes |
| GO:0007413 | axonal fasciculation | 1.3333 | 4 | yes |
| GO:0008347 | glial cell migration | 1.3333 | 4 | yes |
| GO:0010935 | regulation of macrophage cytokine production | 1.3333 | 6 | yes |
| GO:0021799 | cerebral cortex radially oriented cell migration | 1.3333 | 7 | yes |
| GO:0021801 | cerebral cortex radial glia-guided migration | 1.3333 | 6 | yes |
| GO:0022030 | telencephalon glial cell migration | 1.3333 | 5 | yes |
| GO:0033599 | regulation of mammary gland epithelial cell proliferation | 1.3333 | 6 | yes |
| GO:0033601 | positive regulation of mammary gland epithelial cell proliferation | 1.3333 | 5 | yes |
| GO:0034163 | regulation of toll-like receptor 9 signaling pathway | 1.3333 | 7 | yes |
| GO:0034165 | positive regulation of toll-like receptor 9 signaling pathway | 1.3333 | 7 | yes |
| GO:0035022 | positive regulation of Rac protein signal transduction | 1.3333 | 8 | yes |
| GO:0035441 | cell migration involved in vasculogenesis | 1.3333 | 4 | yes |
| GO:0051292 | nuclear pore complex assembly | 1.3333 | 6 | yes |
| GO:0060317 | cardiac epithelial to mesenchymal transition | 1.3333 | 6 | yes |
| GO:0060907 | positive regulation of macrophage cytokine production | 1.3333 | 7 | yes |
| GO:0061081 | positive regulation of myeloid leukocyte cytokine production involved in immune response | 1.3333 | 7 | yes |
| GO:0090156 | intracellular sphingolipid homeostasis | 1.3333 | 4 | yes |
| GO:0106030 | neuron projection fasciculation | 1.3333 | 7 | yes |
| GO:1901186 | positive regulation of ERBB signaling pathway | 1.3333 | 6 | yes |
| GO:1902622 | regulation of neutrophil migration | 1.3333 | 5 | yes |
| GO:1902624 | positive regulation of neutrophil migration | 1.3333 | 6 | yes |
| GO:1905521 | regulation of macrophage migration | 1.3333 | 6 | yes |
| GO:1905523 | positive regulation of macrophage migration | 1.3333 | 7 | yes |
| GO:1905550 | regulation of protein localization to endoplasmic reticulum | 1.3333 | 6 | yes |
| GO:1905552 | positive regulation of protein localization to endoplasmic reticulum | 1.3333 | 6 | yes |
| GO:1905578 | regulation of ERBB3 signaling pathway | 1.3333 | 6 | yes |
| GO:1905580 | positive regulation of ERBB3 signaling pathway | 1.3333 | 7 | yes |
| GO:1905651 | regulation of artery morphogenesis | 1.3333 | 5 | yes |
| GO:1905653 | positive regulation of artery morphogenesis | 1.3333 | 5 | yes |
| GO:2000172 | regulation of branching morphogenesis of a nerve | 1.3333 | 5 | yes |
| GO:2000345 | regulation of hepatocyte proliferation | 1.3333 | 6 | yes |
| GO:2000347 | positive regulation of hepatocyte proliferation | 1.3333 | 7 | yes |
| GO:2001212 | regulation of vasculogenesis | 1.3333 | 5 | yes |
| GO:2001213 | negative regulation of vasculogenesis | 1.3333 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BCL2_HUMAN | [view interactions] | Low throughput | no | no |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
| NECD_HUMAN | [view interactions] | Low throughput | no | no |
| CNTP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RT4I1_HUMAN | [view interactions] | Low throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WWP1_HUMAN | [view interactions] | Low throughput | no | yes |
| RTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BACE1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITAV_HUMAN | [view interactions] | Low throughput | no | yes |
| ITA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| S1PR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ATLA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RTN4R_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HS74L_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LIRB2_HUMAN | [view interactions] | Low throughput | no | no |
| LIRB3_HUMAN | [view interactions] | Low throughput | no | no |
| LIRB5_HUMAN | [view interactions] | Low throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| MEP1B_HUMAN | [view interactions] | High throughput | no | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMT1A_HUMAN | [view interactions] | High throughput | no | no |
| ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| S15A4_HUMAN | [view interactions] | High throughput | no | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX4_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POTE1_HUMAN | [view interactions] | High throughput | no | no |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| PLRKT_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| CLN8_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P5F1B_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRX1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| SPAST_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGCZ_HUMAN | [view interactions] | High throughput | no | no |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| TBL2_HUMAN | [view interactions] | High throughput | no | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPD2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIAO1_HUMAN | [view interactions] | High throughput | no | yes |
| HSDL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| TMT1B_HUMAN | [view interactions] | High throughput | no | no |
| F241A_HUMAN | [view interactions] | High throughput | no | yes |
| RTN2_HUMAN | [view interactions] | High throughput | no | no |
| TMM43_HUMAN | [view interactions] | High throughput | no | no |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| SCAM1_HUMAN | [view interactions] | High throughput | no | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| SCAM2_HUMAN | [view interactions] | High throughput | no | no |
| PRAF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F210B_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| AT1B2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM128_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF1_HUMAN | [view interactions] | High throughput | no | yes |
| TM208_HUMAN | [view interactions] | High throughput | no | yes |
| ZPLD1_HUMAN | [view interactions] | High throughput | no | no |
| FPR2_HUMAN | [view interactions] | High throughput | no | yes |
| VSIG1_HUMAN | [view interactions] | High throughput | no | no |
| TM222_HUMAN | [view interactions] | High throughput | no | no |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| DIESL_HUMAN | [view interactions] | High throughput | no | yes |
| GP161_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| TMM88_HUMAN | [view interactions] | High throughput | no | yes |
| T4S5_HUMAN | [view interactions] | High throughput | no | no |
| CKLF5_HUMAN | [view interactions] | High throughput | no | yes |
| GPV_HUMAN | [view interactions] | High throughput | no | no |
| TM169_HUMAN | [view interactions] | High throughput | no | yes |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| S22A4_HUMAN | [view interactions] | High throughput | no | yes |
| LPAR6_HUMAN | [view interactions] | High throughput | no | no |
| HPPD_HUMAN | [view interactions] | High throughput | no | no |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SVOPL_HUMAN | [view interactions] | High throughput | no | no |
| ITA6_HUMAN | [view interactions] | High throughput | no | yes |
| NK3R_HUMAN | [view interactions] | High throughput | no | no |
| MALL_HUMAN | [view interactions] | High throughput | no | no |
| TM9S1_HUMAN | [view interactions] | High throughput | no | yes |
| DHC24_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| PILRB_HUMAN | [view interactions] | High throughput | no | yes |
| NSMA_HUMAN | [view interactions] | High throughput | no | yes |
| TEX2_HUMAN | [view interactions] | High throughput | no | yes |
| F241B_HUMAN | [view interactions] | High throughput | no | yes |
| MOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| LETM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OAT_HUMAN | [view interactions] | High throughput | no | yes |
| HYEP_HUMAN | [view interactions] | High throughput | no | no |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| CF047_HUMAN | [view interactions] | High throughput | no | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EI24_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| COX5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REEP4_HUMAN | [view interactions] | High throughput | no | no |
| CP51A_HUMAN | [view interactions] | High throughput | no | no |
| HCDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPIL1_HUMAN | [view interactions] | High throughput | no | no |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCL3_HUMAN | [view interactions] | High throughput | no | no |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| RDH11_HUMAN | [view interactions] | High throughput | no | no |
| CLMN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DOCK6_HUMAN | [view interactions] | High throughput | no | yes |
| RAB21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHRS7_HUMAN | [view interactions] | High throughput | no | yes |
| ABHDA_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| ATLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUF2_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX15_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMA4_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| DPB1_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| ATLA3_HUMAN | [view interactions] | High throughput | no | no |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIM43_HUMAN | [view interactions] | High throughput | no | no |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| RYR3_HUMAN | [view interactions] | High throughput | no | no |
| CIRBP_HUMAN | [view interactions] | High throughput | no | no |
| LPIN3_HUMAN | [view interactions] | High throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHRF2_HUMAN | [view interactions] | High throughput | no | no |
| PRDX4_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM65_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DIC_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IBP7_HUMAN | [view interactions] | High throughput | no | no |
| PTN5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10AG_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| DERL2_HUMAN | [view interactions] | High throughput | no | yes |
| DDX46_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| GRHPR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| WASC4_HUMAN | [view interactions] | High throughput | no | yes |
| SIR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SBNO1_HUMAN | [view interactions] | High throughput | no | yes |
| SSRG_HUMAN | [view interactions] | High throughput | no | yes |
| SNX2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| APMAP_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| SYT16_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3G_HUMAN | [view interactions] | High throughput | no | yes |
| ZFY21_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN2_HUMAN | [view interactions] | High throughput | no | no |
| AR6P1_HUMAN | [view interactions] | High throughput | no | yes |
| TCOF_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| SPG21_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| CERT_HUMAN | [view interactions] | High throughput | no | yes |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| PRR13_HUMAN | [view interactions] | High throughput | no | yes |
| PTH2_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH4_HUMAN | [view interactions] | High throughput | no | no |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| RHDF2_HUMAN | [view interactions] | High throughput | no | yes |
| RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| RB33A_HUMAN | [view interactions] | High throughput | no | no |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| 5HT2C_HUMAN | [view interactions] | High throughput | no | no |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BKRB1_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR4_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| CLTR2_HUMAN | [view interactions] | High throughput | no | no |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| GPR35_HUMAN | [view interactions] | High throughput | no | no |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |